aspirin has been researched along with indomethacin in 2229 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1615 (72.45) | 18.7374 |
| 1990's | 314 (14.09) | 18.2507 |
| 2000's | 195 (8.75) | 29.6817 |
| 2010's | 95 (4.26) | 24.3611 |
| 2020's | 10 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, RL; Lanza, T; Pessolano, AA; Risley, EA; Shen, TY; Van Arman, CG; Witzel, B | 1 |
| Crowley, HJ; Dalton, C; Fahrenholtz, KE; Germane, N; Silverzweig, MZ; Simko, BA | 1 |
| Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE | 1 |
| Corleto, LA; Knaus, EE; Redda, K | 1 |
| Banner, BL; Cohen, N; Lopresti, RJ | 1 |
| Duru, S; Erdogan, H; Palaska, E; Safak, C; Sunal, R | 1 |
| Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM | 1 |
| Hall, SE; Han, WC; Harris, DN; Haslanger, MF; Ogletree, ML | 1 |
| Lazer, ES; Matteo, MR; Possanza, GJ | 1 |
| Feller, DR; Kamanna, VS; Kim, SK; Kim, SU; McCreery, RL; Newman, HA; Romstedt, KJ; Sternitzke, KD; Tehim, AK; Witiak, DT | 1 |
| Cherkofsky, SC; Gregory, WA; Haber, SB; Hewes, WE; Leadbetter, MR; Sharpe, TR; Smith, DH; Whitney, JG | 1 |
| Sancilio, LF; Sleevi, MC; Walsh, DA | 1 |
| Schiatti, P; Selva, D; Toja, E | 1 |
| Gries, J; König, H; Kretzschmar, R; Kunze, J; Lebkücher, R; Lehmann, HD; Lenke, D; Thyes, M | 1 |
| Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ | 1 |
| Corleto, LA; Knaus, EE; Yeung, JM | 2 |
| DiPasquale, G; Fabian, AC; Genzer, JD; Kasulanis, CF; Lindo, N; Lutomski, C; Schwartz, ML; Shavel, J; Sircar, JC; Zinnes, H | 1 |
| Copeland, RA; Covington, M; Trzaskos, JM; Wilkerson, WW | 1 |
| Adam, G; Bizot-Espiard, JG; Caignard, DH; Flouzat, C; Guillaumet, G; Jamoneau, P; Pfeiffer, B; Renard, P; Viaud, MC | 1 |
| Galbraith, W; Gans-Brangs, K; Grubb, M; Hewes, WE; Jaffee, B; Kenney, JP; Kerr, J; Wilkerson, WW; Wong, N | 1 |
| Bohlin, L; Farah, M; Ogundaini, A; Perera, P; Samuelsson, G | 1 |
| Fang, SC; Hsu, MF; Ko, FN; Lin, CN; Lin, HC; Lu, CM; Shieh, BJ; Teng, CM; Wang, JP | 1 |
| Chen, CC; Hsin, WC; Huang, YL; Ko, FN; Ou, JC; Teng, CM | 1 |
| Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
| Bohlin, L; el-Seedi, H; Noreen, Y; Perera, P | 1 |
| Hopper, AT; Witiak, DT; Ziemniak, J | 1 |
| Chan, BS; Lu, R; Schuster, VL | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chilmonczyk, Z; Cybulski, J; Dubis, AT; Kaliszan, R; Lachowska, B; Lozowicka, B; Petrusewicz, J; Poplawski, J; Siluk, D; Strzałkowska, M; Witkowski, S | 1 |
| Hour, MJ; Huang, LJ; Ko, TC; Kuo, SC; Lee, KH; Lien, JC; Teng, CM | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Arihara, S; Inoue, M; Matsumoto, H; Matsumoto, Y; Miyataka, H; Sakakibara, C; Yoshikawa, K | 1 |
| Knaus, EE; Praveen Rao, PN; Velázquez, C | 1 |
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Gust, R; Kircher, B; Langer, T; Ott, I; Schumacher, P; Schuster, D; Wiglenda, T | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Akaho, E; Ali, HI; Kakuta, H; Oda, H; Oshiki, T; Sasaki, K; Sugimoto, Y; Tai, A; Takamatsu, K; Zheng, X | 1 |
| Ertan, M; Küpeli, E; Tozkoparan, B; Yeşilada, E | 1 |
| Chiang, SZ; Hsieh, PW; Hwang, TL; Wu, CC; Wu, CI; Wu, YC | 1 |
| Blobaum, AL; Marnett, LJ | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Citro, ML; Keefer, LK; Knaus, EE; Praveen Rao, PN; Velázquez, CA | 1 |
| Aktay, G; Gökhan-Kelekçi, N; Göktaş, O; Işik, S; Kiliç, E; Köysal, Y; Ozalp, M; Salgin-Gökşen, U | 1 |
| Bilgin, AA; Gökhan-Kelekçi, N; Kendi, E; Küpeli, E; Ozgen, O; Salgin, U; Uçar, G; Yabanoğlu, S; Yeşilada, A; Yeşilada, E | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ray, SM; Sharma, M | 2 |
| El-Enany, MM; El-Gazzar, AR; Mahmoud, MN | 1 |
| Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM | 1 |
| Abdel-Hafez, ShH | 1 |
| Chen, QH; Citro, ML; Keefer, LK; Knaus, EE; Velázquez, CA | 1 |
| Harada, S; Kakuta, H; Oda, H; Sasaki, K; Sugimoto, Y; Tai, A; Zheng, X | 1 |
| Chiang, SZ; Hsieh, PW; Lo, YC; Shih, YT; Wu, CC; Wu, YC | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Aridoss, G; Jeong, YT; Kabilan, S; Parthiban, P; Prakash, M; Ramachandran, R | 1 |
| El-Gazzar, AB; Hafez, HN | 1 |
| el-Gazzar, AB; Hafez, HN; Nawwar, GA | 1 |
| Begum, A; Choudhary, MI; Lontsi, D; Mbazoa, CD; Ngninzeko, FN; Ngoumfo, RM; Ngounou, GE; Qadir, MI; Tchamadeu, CV | 1 |
| Abdellatif, KR; Chowdhury, MA; Das, D; Dong, Y; Knaus, EE; Suresh, MR; Velázquez, CA; Yu, G | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Gökçe, M; Küpeli, E; Utku, S | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Aktay, G; Aytaç, SP; Göktaş, O; Kaynak, FB; Tozkoparan, B; Unüvar, S | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| El-Gazzar, AR; Hafez, HN; Nawwar, GA | 1 |
| Gaba, M; Gaba, P; Sharma, V; Singh, D; Singh, S | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ambreen, N; Choudhary, MI; Jalil, S; Khan, KM; Mughal, UR; Perveen, S | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| El Gendy, MA; Jain, S; Jurasz, P; Kashfi, K; Tran, S; Velázquez-Martínez, CA | 1 |
| Ballabeni, V; Barocelli, E; Brullo, C; Bruno, O; Cichero, E; Domenichini, G; Flammini, L; Fossa, P; Giorgio, C; Rocca, M; Saccani, F | 1 |
| Bhardwaj, A; Huang, Z; Kaur, J; Knaus, EE | 1 |
| Gust, R; Huang, W; Liu, W; Qian, H; Zhang, H; Zhang, T; Zhou, J; Zhu, H | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Banoglu, E; Çalışkan, B; Çiftçi, M; Levent, S; Özkan, Y; Ünver, H; Yenicesu, I | 1 |
| Bruno, A; Dovizio, M; Lavecchia, A; Malerba, P; Marcantoni, E; Patrignani, P; Perrone, MG; Scilimati, A; Simone, L; Tacconelli, S; Vitale, P | 1 |
| Capim, SL; Dos Santos, GC; Gonçalves, GM; Marinho, BG; Vasconcellos, ML | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bhatti, R; Kaur, M; Sharma, S; Singh, A; Singh, P | 1 |
| Abe, H; Arisawa, M; Ito, M; Ito, Y; Kasaya, Y; Obata, T; Sasaki, T; Shuto, S; Yamano, A | 1 |
| Alfei, S; Ballabeni, V; Barocelli, E; Bertoni, S; Di Braccio, M; Flammini, L; Giorgio, C; Grossi, G; Tognolini, M | 1 |
| Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C | 1 |
| Cabral, LM; Castro, HC; Craik, CS; de Souza, AMT; Dias, LRS; Lourenço, AL; Mello, JFR; Muri, EMF; Rodrigues, CR; Saito, MS; Salvador, RRS; Sathler, PC; Silva, LA; Vera, MAF | 1 |
| Kongsaeree, P; Lhinhatrakool, T; Prabpai, S; Seeka, C; Sutthivaiyakit, S; Tewtrakul, S | 1 |
| Janeba, Z; Jansa, P; Kalčic, F; Kolman, V; Zídek, Z | 1 |
| Abdel-Maksoud, MS; Ali, EMH; Oh, CH | 1 |
| Chen, LZ; Huang, X; Jiao, MM; Liu, MM; Liu, XH; Shi, JB; Tang, WJ; Wang, BS | 1 |
| Abid, OU; Ahmad, A; Ahmad, S; Ayaz, M; Hussain, F; Jan, MS; Mahmood, F; Rashid, U; Sadiq, A; Ullah, F | 1 |
| Chen, R; Guo, Z; Han, X; Wang, S; Xu, Y; Yang, Y; Zhu, Q | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Abbatiello, ER; Kaminsky, M; Weisbroth, S | 1 |
| Allouche, G; Dray, F; Ruff, F | 1 |
| Khalili-Varasteh, H; Legros, J; Rosner, I | 1 |
| Béguin, F | 1 |
| Crocker, AD; Willavoys, SP | 1 |
| Kamikawa, Y; Shimo, Y | 1 |
| Collins, AJ; Crook, D; Rose, AJ | 1 |
| Haslock, I | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 2 |
| Jobin, F | 2 |
| Van Nueten, JM | 1 |
| Boyle, E; Freeman, PC; Goudie, AC; Mangan, FR; Thomson, M | 1 |
| Benzoni, J; Deraedt, R; Jouquey, S; Peterfalvi, M | 1 |
| El-Sabban, F; Rosenblum, WI | 3 |
| Bertoni, MP; De Gaetano, G; Roncaglioni, MC; Tonolli, MC | 1 |
| Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T | 1 |
| Halpern, LM | 2 |
| Bekemeier, H; Giessler, AJ; Vogel, E | 1 |
| Bennett, A; Curwain, BP | 1 |
| Huskisson, EC | 1 |
| Akimoto, T; Saito, T; Tachizawa, H; Tsukada, W | 1 |
| Huston, GJ | 2 |
| Hayden, LJ; Thomas, G; West, GB | 1 |
| Whittle, BJ | 3 |
| Warne, PJ; West, GB | 1 |
| Gruetter, DY; Ignarro, LJ | 1 |
| Brooks, PM; Dick, WC; Sharma, JN; Zeitlin, IJ | 2 |
| Bleys, J; De Wilde, A; van Bogaert, A | 1 |
| Turner, P | 1 |
| Karambasis, T; Mountokalakis, T | 1 |
| Buisseret, PD; Heinzelmann, DI; Lessof, MH; Youlten, LF | 1 |
| Bernstein, BH; Hanson, V; Hicks, R; Kent, JT; King, K; Kornreich, H; Singsen, BH | 1 |
| Ljunggren, B | 1 |
| Kawai, K; Kuzuna, S; Morimoto, S | 1 |
| Bhat, SG; Hayaishi, O; Yamamoto, S; Yoshimoto, T | 1 |
| Nozu, K | 1 |
| Vargaftig, BB | 2 |
| Girit, EZ; Kay, JE; Phillips, CA | 1 |
| Gafni, Y; Raz, A; Schwartzman, M | 1 |
| Brooks, PM | 1 |
| Chand, S; Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ | 1 |
| Inamasu, M; Morita, T; Sasaki, Y; Shinjo, A | 1 |
| Bailey, JM; Bryant, RW | 1 |
| Shoyab, M | 1 |
| Collins, AC; George, FR | 1 |
| Cuatrecasas, P; McConnell, RT; Siegel, MI | 1 |
| Castrucci, G; Ciabattoni, G; De Salvo, A; Parachini, M; Patrono, C; Pinca, E; Pugliese, F; Satta, MA | 1 |
| Cockbill, SR; Heptinstall, S; Taylor, PM | 1 |
| Kabayashi, I; Mori, M; Tonooka, N; Tsuyusaki, K | 1 |
| Martelli, NA | 1 |
| Aurell, M; Hansson, L; Rudin, A; Westberg, G | 1 |
| Leffler, CW; Passmore, JC | 1 |
| Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ | 3 |
| Cha, CJ; Clowes, GH; Henry, WL; Salomon, JC | 1 |
| Kupor, LR; Lowance, DC; McPhaul, JJ | 1 |
| Vogel, HG | 1 |
| Boneu-Valmalette, A; Bugat, R; Combes, PF; David, JF | 1 |
| Abiko, Y; Ito, K; Otsuka, R; Takiguchi, H | 1 |
| Nieminen, L; Raekallio, J | 1 |
| Baker, JW; Coombes, RC; Ford, HT; Gazet, JC; Nash, AG; Neville, AM; Powles, JT | 1 |
| Akbar, M; Burke, G; Park, S; Richman, R; Yu, S | 1 |
| Bauminger, S; Koch, Y; Naor, Z; Zor, U | 1 |
| Boeynaems, JM; Dumont, JE; Van Sande, J | 1 |
| Neufeld, AH; Page, ED | 1 |
| Levine, L; McGuire, MB; Robinson, DR | 1 |
| Castracane, VD; Shaikh, AA; Tankenow, LF | 1 |
| Stancíková, M; Trnavský, K | 1 |
| Couropmitree, C; Feldman, D | 1 |
| Bonta, IL; Vincent, JE; Zijlstra, FJ | 1 |
| Charbonnel, B | 1 |
| Guignot, B; Pelletier, M; Prost, G; Tolot, F | 1 |
| Lands, WE; Majerus, PW; Rome, LH; Roth, GJ | 1 |
| Haslam, RJ | 1 |
| Dowsett, M; Eastman, AR; Easty, DM; Easty, GC; Neville, AM; Powles, TJ | 1 |
| Zurier, RB | 1 |
| Champion, S; Haye, B; Jacquemin, C | 2 |
| Koch, R; Naor, Z; Zor, U | 1 |
| Barden, N; Bergeron, L; Betteridge, A | 1 |
| Gurevich, MA; Iankovskaia, MO; Odinokova, VA; Paleev, NR; Surovikina, MS | 2 |
| George, DT; Mapes, CA; Sobocinski, PZ | 1 |
| Hamet, P; Oates, JA; Potts, JT; Segre, GV; Seyberth, HW; Sweetman, BJ | 1 |
| Hamamdzić, M; Malik, KU | 1 |
| Carr, DW; Gerrard, JM; Glass, DB; Goldberg, ND; Townsend, D; White, JG | 1 |
| Shier, WT | 1 |
| Claesson, HE; Hammarström, S; Lindgren, JA | 2 |
| Dowsett, M; Easty, DM; Easty, GC; Gazet, JC; Neville, AM; Powles, TJ | 1 |
| Berl, T; Czaczkes, W; Horowitz, J; Raz, A; Wald, H | 1 |
| Antoni, FA; Nagy, K; Siklós, P; Spät, A; Szirányi, K | 1 |
| Aberg, G; Andersson, RG; Brattsand, R; Ericsson, E; Lundholm, L | 1 |
| Austen, KF; Goetzl, EJ; Schoepflin, GS | 1 |
| Faure, G; Gaucher, A; Netter, P; Royer, RJ; Tamisier, JN | 1 |
| Davis, BB; Herman, CA; Joshi, S; Mattammal, MB; Zenser, TV | 1 |
| Hayasaka, S; Sears, M | 1 |
| Su, C; Su, MO; Tsuru, H | 1 |
| Boss, GR; Seegmiller, JE | 1 |
| Mehta, J; Simchowitz, L; Spilberg, I | 1 |
| Brinckerhoff, CE; Fahey, JV; Harris, ED; McMillan, RM | 2 |
| Cavagnini, F; Di Landro, A; Invitti, C; Maraschini, C; Pinto, ML | 1 |
| Ferber, RH; Parrish, SL; Vigdahl, RL | 1 |
| Newton, AA | 1 |
| Krzanowski, JJ; Polson, JB; Szentivanyi, A | 1 |
| Waitzman, MB | 1 |
| Paterson, CA; Pfister, RR | 1 |
| Mosler, KH | 1 |
| Linka, F; Mosler, KH | 1 |
| Aylward, M; Maddock, J; Parker, RJ; Wheeldon, R | 1 |
| Collins, A,; Crook, D | 1 |
| Cameron, JS; Clark, WF; George, CR | 1 |
| McKnight, IS; Temple, DM | 1 |
| Bell, MA; Brooks, PM; Buchanan, WW; Mason, DI | 1 |
| Brune, K; Graf, P; Rainsford, KD | 1 |
| Bonta, IL; Bult, H | 1 |
| Rich, WJ | 1 |
| Rainsford, KD | 4 |
| Egan, RW; Gale, PH; Kuehl, FA; VandenHeuvel, WJ | 1 |
| Brown, KA; Collins, AJ | 1 |
| Menguy, R | 2 |
| Bertolotto, M; Brida di Priò, S; Cottafava, F; Moni, L | 1 |
| Hollingworth, RM; Holsapple, MP; Pfister, WR; Yim, GK | 1 |
| Kunin, CM; Proctor, RA | 1 |
| Evens, RP | 1 |
| Cummings, NA; Harris, DC | 1 |
| Mowat, AG | 1 |
| Chevrier, MM; Dumeur, G; Hertz, F; Lwoff, JM | 1 |
| Bourel, M; Catheline, M; Delbary, A; Durand, B; Le Treut, A; Pawlotsky, Y | 1 |
| Given, KM; Green, D; Rossi, EC; Ts'ao, C; Whipple, JP | 1 |
| Roe, RL | 2 |
| Buchanan, GR; Handin, RI; Levine, PH; Martin, V; Scoon, K | 1 |
| Chand, N; Eyre, P | 1 |
| Cazenave, JP; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Reimers, HJ | 1 |
| Fletcher, JR; Ramwell, PW | 2 |
| Eakins, KE | 1 |
| Aromaa, U; Asp, K | 1 |
| Bettin, KM; Schlievert, PM; Watson, DW | 1 |
| Adkinson, NF; Kordansky, D; Norman, PS; Rosenthal, RR | 1 |
| Kajanoja, P | 1 |
| Karim, SM | 1 |
| Bouhuys, A; Kreisman, H; Schachter, EN | 1 |
| Bourgain, RH | 1 |
| Astoin, M; Castes, M; Lynch, NR; Salomon, JC | 1 |
| Bartel, J | 1 |
| Dyck, WP | 1 |
| Gothoni, G; Rejholec, V; Tokola, O; Vapaatalo, H | 1 |
| Reinicke, C; Vesel, G | 1 |
| Meier-Sydow, J; Mitrou, PS | 1 |
| Landgraf, R; Landgraf-Leurs, MM | 1 |
| Ahnfelt-Rønne, I; Arrigoni-Martelli, E | 1 |
| Chen, M; Robertson, RP | 1 |
| Sacerdoti, G; Severino, R | 1 |
| Novo, S; Strano, A | 1 |
| Gerrard, JM; Rao, GH; White, JG | 1 |
| Del Beccaro, EJ; Heggers, JP; Robson, MC | 2 |
| Cuthbert, J; Saeed, SA | 1 |
| Duffy, J; Estrada, RG; Gold, KD; Person, DA; Sharp, JT | 1 |
| Majerus, PW; Roth, GJ; Shen, TY; Stanford, N | 1 |
| Glenn, TM; Wilkerson, RD | 1 |
| Collins, AJ; Crook, D | 1 |
| Bowden, RE; Gill, JR; Keiser, HR; Radfar, N; Taylor, AA | 1 |
| Dipalma, JR | 1 |
| Boutwell, RK; Rice, HM; Verma, AK | 1 |
| Maclouf, J; Rigaud, M; Sors, H | 1 |
| Vane, JR | 2 |
| Dusting, GJ; Moncada, S; Mullane, KM; Salmon, JA; Vane, JR | 1 |
| Asano, M; Hidaka, H | 1 |
| Franzini, P | 1 |
| Williams, RC | 1 |
| Albers, JW; Itskovitz, HD; Kochar, MS | 1 |
| Ciammaichella, A | 1 |
| Csendes, A; Defilippi, C; Pantoja, JL; Valenzuela, JE | 1 |
| Bergamaschi, M; Ceserani, R; Pierucci, L; Pogliani, E; Spelta, A | 1 |
| Nesheim, B | 1 |
| Spisani, S; Traniello, S; Vanzini, G | 1 |
| Barbieri, EJ; Rosenbaum, ES | 1 |
| Becker, EL; O'Flaherty, JT; Showell, HJ; Ward, PA | 2 |
| Kawamoto, H; Komatsu, H; Kubota, T; Yamada, T | 1 |
| Huidobro-Toro, JP; Way, EL | 1 |
| Latour, JG; Leger-Gauthier, C | 1 |
| Ishikawa, Y; Wada, T | 1 |
| Anderson, WH; Krzanowski, JJ; Polson, JB; Szentivanyi, A | 1 |
| Bokoch, GM; Reed, PW | 1 |
| Collier, HO; McDonald-Gibson, WJ | 1 |
| Walker, R; Wilson, KA | 1 |
| Chen, TT; Lanza, FL; Nelson, RS; Rack, MF; Royer, GL; Seckman, CE | 1 |
| Sasaki, H | 1 |
| Ally, AI; Cunnane, SC; Horrobin, DF; Karmali, RA; Karmazyn, M; Manku, MS; Morgan, RO; Oka, M | 1 |
| Kauppila, A; Puolakka, J; Ylikorkala, O | 1 |
| Ciccolunghi, SN; Reddrop, R; Schubiger, BI | 1 |
| Eaglestein, WH; Ginsberg, LD; Mertz, PM | 1 |
| Naik, SR; Sattur, PB; Sheth, UK | 1 |
| Ohtsuki, H; Okabe, S; Tabata, K | 1 |
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| Carl-McGrath, S; Chen, J; Ebert, MP; Gu, P; Hoffmann, J; Kubisch, C; Malfertheiner, P; Röcken, C; Schäfer, C; Treiber, G | 1 |
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| Augustyniak, ME; Cochran, ED; Ellis, JL; Fang, X; Garvey, DS; Janero, DR; Letts, LG; Martino, AM; Melim, TL; Murty, MG; Richardson, SK; Schroeder, JD; Selig, WM; Trocha, AM; Wexler, RS; Wey, SJ; Young, DV; Zemtseva, IS; Zifcak, BM | 1 |
| Elsas, MI; Elsas, PX; Kanaoka, Y; Lam, BK; Mendonça-Sales, SC; Queto, T | 1 |
| El-Gazzar, AR; Hafez, HN; Hussein, HA | 1 |
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| Harrison, JS; Jamshidi, F; Studzinski, GP; Wang, X; Zhang, J | 1 |
| Johri, RK; Khajuria, A; Khajuria, RK; Qazi, GN; Singh, J; Singh, S; Taneja, SC | 1 |
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| Dai, Q; Li, EL; Shen, GF; Wu, SM; Xiao, SD; Zhang, YJ; Zhu, HY | 1 |
| Hadjipavlou-Litina, D; Kokotos, G; Magrioti, V; Makriyannis, A; Naxakis, G | 1 |
| Araújo, JR; Gonçalves, P; Martel, F; Pinho, MJ | 1 |
| Abrahão, A; Castro, P; Cavalcante, MC; Dos Reis, LC; Koatz, VL; Nasser, H; Porto, LC; Quintas, LE; Rezende, DC; Riça, I; Valença, SS | 1 |
| Imamura, S; Ito, K; Momma, K; Nakanishi, T; Sugiyama, K; Sun, F; Toyoshima, K | 1 |
| Colak, MS; Gökçe, M; Küpeli, E; Sahin, MF | 1 |
| Kock, JL; Kriel, WM; Leeuw, NJ; Ncango, DM; Pohl, CH; Swart, CW; van Wyk, PW | 1 |
| Ishar, MP; Paneerselvam, P; Raj, T; Rather, BA; Reddy, A; Sivakumar, S | 1 |
| Buerke, M; Chen, L; Frister, A; Hofmann, B; Lautenschläger, M; Loppnow, H; Luther, T; Müller-Werdan, U; Rose-John, S; Schlitt, A; Silber, RE; Song, N; Werdan, K; Zhang, L | 1 |
| Catteau, J; Hennebert, C; Hennebert, O; Laudenbach, V; Legros, H; Leroux, P; Marret, S | 1 |
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| Brzozowski, T; Konturek, SJ; Kwiecien, S; Mazurkiewicz-Janik, M; Pajdo, R; Pawlik, M; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z | 1 |
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| Chen, W; Cherukuri, MK; Flores-Santana, W; Gorczynski, MJ; King, SB; Mitchell, JB; Moody, T; Shoman, ME; Thetford, A; Velázquez, C; Wink, DA | 1 |
| Ahmad, M; Fatima, N; Imran, H; Rahman, A; Rehman, Z; Sohail, T; Yaqeen, Z | 1 |
| Fujino, H; Kato, T; Kawashima, T; Murayama, T; Oyama, S | 1 |
| Chang, CH; Chen, YC; Fan, SC; Huang, CH; Liu, C; Tsai, AL; Wu, CC | 1 |
| Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH | 1 |
| Avril, S; Bronger, H; Cerny, C; Kiechle, M; Kraeft, S; Schmitt, M; Schwarz-Boeger, U; Stöckel, A | 1 |
| Dejucq-Rainsford, N; Desdoits-Lethimonier, C; Jégou, B; Kristensen, DM; Le Fol, V; Leffers, H; Lesné, L | 1 |
| Aliaga, ME; Lopez-Alarcón, C; Sandoval-Acuña, C; Speisky, H | 1 |
| Asanuma, M; Kikkawa, Y; Kimoto, N; Miyazaki, I; Miyoshi, K; Murakami, S; Takeshima, M | 1 |
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| Chen, M; Dai, K; Zhang, J; Zhang, M; Zhang, W; Zhao, L | 1 |
| Bebawy, M; Haghi, M; Mamlouk, M; Mamlouk, S; Mulay, V; Traini, D; Young, PM | 1 |
| Donovan, M; Femino, JE; Fredericks, D; George, M; Lack, WD; Nepola, J; Petersen, E; Smucker, J | 1 |
| Dimaline, R; Dockray, GJ; Kenny, S; Lyons, S; Moore, AR; Murugesan, SV; Pritchard, DM; Steele, I; Tiszlavicz, L; Varro, A | 1 |
| Hirasawa, N; Kotake, D | 1 |
| Albert, O; Bensalah, K; Dejucq-Rainsford, N; Desdoits-Lethimonier, C; Guillé, F; Jégou, B; Legrand, A; Lesné, L | 1 |
| Geibel, JP; Geibel, P; Kaur, S; Kohut, DL; Roginiel, AC; Saleh, AM; Singh, H; Weber, T | 1 |
| Birincioglu, M; Demir, O; Demirci, B; Dost, T | 1 |
| Dong, L; Jurban, BJ; Sharma, NP; Smith, WL | 1 |
| Balaguer, P; Ben Maamar, M; Chevrier, C; Coiffec, I; Dejucq-Rainsford, N; Desdoits-Lethimonier, C; Jégou, B; Kristensen, DM; Lavoué, V; Mazaud-Guittot, S; Nicolas Nicolaz, C; Poulain, P | 1 |
| Bezzi, P; Cali, C; Lopatar, J; Petrelli, F; Pucci, L | 1 |
| Du, L; Jin, Y; Li, M; Liu, B; Zhu, W; Zuo, J | 1 |
| de Graaf, IA; Groothuis, GM; Niu, X; van der Bij, HA | 1 |
| Alabed, S; Burls, A; Cabello, JB; Irving, GJ; Qintar, M | 1 |
| Abraham-Nordling, M; Håkansson, N; Hjern, F; Mahmood, MW; Wolk, A | 1 |
| Ahamed, SK; Billah, MM; Hassan, MM; Hossain, MS; Moghal, MM; Raju, GS; Rana, SM | 1 |
| Patai, Á; Patai, ÁV; Solymosi, N | 1 |
| Kim, MJ; Rangasamy, S; Shim, Y; Song, JM | 1 |
| Aguilar, MI; Benítez, WV; Bye, R; Calzada, F; Colín, A; Ríos-Gómez, R | 1 |
| Cai, HZ; Sun, GJ; Wang, SK; Yang, LG; Yin, H | 1 |
| Antonov, VG; Butov, SN; Krutetskaia, NI; Krutetskaia, ZI; Kurilova, LS; Naumova, AA | 1 |
| Bucolo, C; Drago, F; Modica, MN; Pittalà, V; Romano, GL; Romeo, G; Salerno, L; Salomone, S; Siracusa, MA | 1 |
| Bie, S; Jiang, Z; Wang, P; Zhang, F; Zhong, T; Zuo, B | 1 |
| Cipollone, F; Creemers, EE; de Ronde, MW; Halliani, A; Kok, MG; Mandolini, C; Meijers, JC; Moerland, PD; Nieuwland, R; Pinto-Sietsma, SJ; Sondermeijer, BM | 1 |
| Jang, IS; Nakamura, M | 1 |
| Dusilová, A; Jansa, P; Kmoníčková, E; Kverka, M; Zídek, Z | 1 |
| Hamaguchi, T; Inagaki, Y; Inoue, S; Iwakawa, S; Okada, M; Tatsumi, A | 1 |
| Choi, KH; Chung, MW; Lee, HJ; Park, JH; Um, SY | 1 |
| Duncton, MA; Singh, R | 1 |
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| Agrawal, R; Assaiya, A; Banerjee, T; Jain, N; Kumar, A; Manivannan, E; Mufti, I; Parmar, HS; Tiwari, S | 1 |
| Yanaka, A | 1 |
| Hernandez-Gonzalez, L; López Juan, MG; Majluf-Cruz, A; Martinez, M; Mayoral-Andrade, G; Perez Campos Mayoral, C; Perez-Campos Mayoral, E; Pérez-Campos, E; Pérez-Campos-Mayoral, L; Pérez-Santiago, AD; Rocha-Núñez, A; Zenteno, E | 1 |
| Hamaguchi, T; Inoue, S; Iwakawa, S; Tatsumi, A | 1 |
| Fujita, T; Kumamoto, E; Mizuta, K; Suzuki, R | 1 |
| Govindaswami, B; Jegatheesan, P; Narasimhan, SR; Nudelman, M | 1 |
| D'Amico, D; Grazzi, L; Grignani, E; Raggi, A; Sansone, E | 1 |
| Ibi, K; Imai, K; Kihara, T; Nejishima, H; Ogawa, H; Senshu, M; Takeda, Y; Yonezawa, Y | 1 |
| Bibire, N; Buron, F; Panainte, A; Profire, L; Routier, S; Sava, A | 1 |
| Brox, R; Hackstein, H | 1 |
| Alexandre-Moreira, MS; Aparecida-Silva, C; Barreiro, EJ; Bispo Júnior, W; da Silva Monteiro, CE; da Silva, TF; de Queiroz, AC; Lima, LM; Zapata-Sudo, G | 1 |
| Affuso, F; Bellavite, P; Fazio, S; McCullough, PA; Pandolfi, S; Zanolin, E | 1 |
| Kowalczyk, A; Kuźmycz, O; Stączek, P | 1 |
| Encío, I; Plano, D; Ramos-Inza, S; Raza, A; Sanmartín, C; Sharma, AK | 1 |
| Díaz-Velis, L; Garrido, G; Garrido-Suárez, BB; Garrido-Valdes, M; Valdes-Gonzalez, M | 1 |
124 review(s) available for aspirin and indomethacin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Structural and functional basis of cyclooxygenase inhibition.
Topics: Animals; Cardiovascular System; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Kinetics; Models, Molecular; Protein Conformation; Risk Assessment | 2007 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Inflammation; Neoplasms; Pyrimidines; Structure-Activity Relationship | 2019 |
[Blood platelets and cardiovascular diseases. IV. Platelet-inhibiting drugs and antithrombotic agents].
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Analgesics; Anti-Inflammatory Agents; Arteriosclerosis; Aspirin; Blood Coagulation; Blood Platelets; Cardiovascular Diseases; Dipyridamole; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; In Vitro Techniques; Indomethacin; Oxyphenbutazone; Phenylbutazone; Platelet Adhesiveness; Platelet Aggregation; Sulfinpyrazone; Thromboembolism; Time Factors | 1976 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin | 1977 |
Drug treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Gold Sodium Thiomalate; Humans; Immunosuppressive Agents; Indomethacin; Penicillamine; Phenylbutazone; Propionates | 1978 |
Vascular reactivity to angiotensin II in human pregnancy.
Topics: Adolescent; Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Volume; Dogs; Female; Haplorhini; Hemoglobin, Sickle; Hemoglobinopathies; Humans; Hypertension; Indomethacin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Prostaglandin Antagonists; Prostaglandins E | 1978 |
[Interactions of salicylates and other nonsteroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Drug Interactions; Fenoprofen; Humans; Indomethacin; Phenylbutazone; Rats; Salicylates | 1977 |
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Indomethacin; Kidney; Kidney Calculi; Kidney Diseases; Lead Poisoning; Lymphoproliferative Disorders; Myeloproliferative Disorders; Phenylbutazone; Platelet Aggregation; Probenecid; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrazinamide; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Uricosuric Agents | 1979 |
Proposed metabolic dysfunctions in diabetic microthromboses and microangiopathy.
Topics: Alprostadil; Aspirin; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dinoprost; Dinoprostone; Humans; Indomethacin; Models, Biological; Platelet Aggregation; Prostaglandins; Prostaglandins E; Prostaglandins F; Thromboxane A2 | 1979 |
[Clinical pharmacology in obstetrics: regulation of the uterus].
Topics: Adrenergic beta-Agonists; Aspirin; Ergotamine; Female; Humans; Indomethacin; Methylergonovine; Obstetric Labor Complications; Obstetric Labor, Premature; Oxytocics; Oxytocin; Papaverine; Pregnancy; Pregnancy Complications; Prostaglandins; Uterine Contraction; Uterus | 1975 |
The role of platelets in glomerulonephritis.
Topics: Adenosine; Antidepressive Agents; Aspirin; Blood Platelets; Complement System Proteins; Endothelium; Glomerulonephritis; Hemostasis; Heparin; Histamine H1 Antagonists; Humans; Immunity; Immunoglobulins; Indomethacin; Kidney Diseases; Meclofenamic Acid; Mopidamol; Phagocytosis; Phenylbutazone; Platelet Aggregation; Prostaglandins; Pyrimidines; Sulfinpyrazone; Tranquilizing Agents; Warfarin | 1975 |
Drug therapy in rheumatic diseases.
Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans; Ibuprofen; Indomethacin; Levamisole; Naproxen; Penicillamine; Phenylbutazone; Rheumatic Diseases; Tolmetin | 1977 |
Nonsteroidal anti-inflammatory drugs: a review. New applications in hypersensitivity reactions of cattle and horses.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Arthritis; Ascariasis; Aspirin; Cattle; Cattle Diseases; Diethylcarbamazine; Guinea Pigs; Horse Diseases; Horses; Hypersensitivity; Indomethacin; Inflammation; Kinins; Leukocytes; Meclofenamic Acid; Phagocytosis; Phenylbutazone; Pneumonia, Atypical Interstitial, of Cattle; Prostaglandin Antagonists; SRS-A | 1977 |
Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier.
Topics: Animals; Aqueous Humor; Aspirin; Blood; Capillary Permeability; Eye; Humans; Indomethacin; Intraocular Pressure; Mechlorethamine; Prostaglandins; Proteins; Rabbits; Uveitis | 1977 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prostaglandin Antagonists; Salicylates; Sheep | 1978 |
[Drug therapy of patent ductus arteriosus in premature and newborn infants].
Topics: Apnea; Aspirin; Chloroquine; Digitalis Glycosides; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases | 1978 |
[Treatment of auto-immune diseases with special reference to their pulmonary manifestations (author's transl)].
Topics: Adrenal Cortex Hormones; Anti-Glomerular Basement Membrane Disease; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Autoimmune Diseases; Collagen Diseases; Humans; Immunosuppressive Agents; Indomethacin; Medicine; Patient Care Team; Pulmonary Fibrosis; Specialization | 1979 |
[Autoimmunity and ocular pathology: critical review].
Topics: Adrenal Cortex Hormones; Arthritis, Reactive; Aspirin; Autoimmune Diseases; Connective Tissue Diseases; Eye Diseases; Gout; Humans; Immunosuppressive Agents; Indomethacin; Ophthalmia, Sympathetic; Rheumatic Diseases; Uveitis; Uveomeningoencephalitic Syndrome | 1979 |
[Prospects of antiaggregant therapy in prevention of atherosclerosis].
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Arteriosclerosis; Aspirin; Blood Coagulation Disorders; Dipyridamole; Epoprostenol; Humans; Hyperlipidemias; Indomethacin; Papaverine; Platelet Aggregation; Prostaglandins; Prostaglandins, Synthetic; Sulfinpyrazone; Xanthines | 1979 |
Vitamin E and platelets: cooperative interactions with nitroblue tetrazolium on inhibition of adhesion, aggregation and secretion.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Microscopy, Electron; Nitroblue Tetrazolium; Platelet Adhesiveness; Platelet Aggregation; Tetrazolium Salts; Thrombin; Vitamin E | 1979 |
Recent aspects of prostaglandin biosynthesis: a review.
Topics: Amino Acids; Animals; Aspirin; Epoprostenol; Fatty Acids, Unsaturated; Feedback; Glutathione Reductase; Humans; Indomethacin; Isomerases; Lipoxygenase; Peroxidases; Phenylbutazone; Phospholipases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane-A Synthase | 1977 |
Inhibitors of prostaglandin, prostacyclin, and thromboxane synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Indomethacin; Muscle Contraction; Prostaglandins; Thromboxane-A Synthase; Thromboxanes; Uterus | 1978 |
The role of the mucosal barrier in drug-induced gastric ulceration and erosions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ethanol; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Hematemesis; Humans; Indomethacin; Nicotine; Occult Blood; Peptic Ulcer; Permeability; Phenylbutazone; Smoking; Stimulation, Chemical; Stomach Ulcer | 1976 |
Prostaglandins and precursors in platelet function.
Topics: Adenosine Diphosphate; Arachidonic Acids; Aspirin; Biotransformation; Blood Platelets; Humans; In Vitro Techniques; Indomethacin; Malondialdehyde; Peroxides; Platelet Aggregation; Prostaglandins; Serotonin; Species Specificity; Thrombin | 1975 |
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Fenoprofen; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; Oxyphenbutazone; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Tolmetin | 1976 |
Rheumatoid arthritis: an overview.
Topics: Adult; Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Female; Gold; Humans; Ibuprofen; Indomethacin; Lupus Erythematosus, Systemic; Male; Osteoarthritis; Phenylbutazone; Radiography | 1976 |
Analgesics and the stomach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indomethacin; Male; Oxyphenbutazone; Peptic Ulcer; Phenylbutazone; Rheumatic Diseases; Salicylates; Stomach Diseases; Stomach Ulcer | 1976 |
Vascular smooth muscle and prostaglandins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Aorta; Aspirin; Epinephrine; Indomethacin; Magnesium; Muscle Contraction; Muscle, Smooth; Portal Vein; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins A; Rats | 1976 |
Principles and applications of manipulation of prostaglandin synthesis in pregnancy.
Topics: Aspirin; Diet; Dietary Fats; Epoprostenol; Fatty Acids, Unsaturated; Female; Humans; Indomethacin; Platelet Aggregation; Pregnancy; Pregnancy Complications; Prostaglandins; Thromboxane A2 | 1992 |
Epithelial renewal in protection and repair of gastroduodenal mucosa.
Topics: Adrenal Cortex Hormones; Aspirin; Epithelium; Ethanol; Gastric Mucosa; Humans; Indomethacin; Prostaglandins; Regeneration | 1991 |
[Indomethacin as a modulator of the activity of natural killer cells (a review of the literature)].
Topics: Adjuvants, Immunologic; Animals; Aspirin; Cells, Cultured; Drug Synergism; Humans; Indomethacin; Killer Cells, Natural; Neoplasms; Neoplasms, Experimental; Prostaglandin Antagonists | 1990 |
The mast cell as a primary effector cell in the pathogenesis of asthma.
Topics: Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Eosinophils; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Leukotriene B4; Mast Cells; Neutrophils; Pulmonary Alveoli; SRS-A | 1986 |
[Hypersensitivity to aspirin and other non-steroidal anti- inflammatory agents--the methods of detecting the hypersensitivity and the development of the state of tolerance].
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Drug Tolerance; Humans; Indomethacin; Skin Tests; Urticaria | 1989 |
Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function.
Topics: Anti-Inflammatory Agents; Aspirin; Epoprostenol; Fenoprofen; Glafenine; Glomerular Filtration Rate; Glomerulonephritis; Humans; Indomethacin; Kidney; Nephritis, Interstitial; Nephrotic Syndrome; Phenacetin; Phenylbutazone; Prostaglandins; Regional Blood Flow; Renin-Angiotensin System; T-Lymphocytes | 1985 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Control of polyunsaturated acids in tissue lipids.
Topics: Acrodermatitis; alpha-Linolenic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Child; Crohn Disease; Cystic Fibrosis; DDT; Dicofol; Ethanol; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Humans; Ichthyosis; Indomethacin; Isomerism; Linoleic Acid; Linoleic Acids; Linolenic Acids; Lipid Metabolism; Lipolysis; Liver Cirrhosis, Alcoholic; Models, Chemical; Myocardial Infarction; Protein-Energy Malnutrition; Reye Syndrome; Structure-Activity Relationship | 1986 |
Prostaglandins and other metabolites of arachidonic acid. An overview for the otolaryngologist.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Humans; Hypersensitivity; Indomethacin; Inflammation; Leukotriene A4; Lipoxygenase; Neoplasms; Phospholipases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxanes | 1985 |
[Gastric mucosa barrier and the effect of non-steroidal anti-inflammatory agents and corticosteroid hormones on the gastric and duodenal mucosa].
Topics: Animals; Aspirin; Duodenum; Gastric Mucosa; Glucocorticoids; Humans; Indomethacin; Intestinal Mucosa; Peptic Ulcer | 1988 |
Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Drug Eruptions; Humans; Ibuprofen; Indomethacin; ortho-Aminobenzoates; Piroxicam; Propionates; Pruritus; Pyrazoles; Pyrazolones; Salicylates; Skin; Skin Diseases; Stevens-Johnson Syndrome; Thiazines | 1985 |
[Derivatives of arachidonic acid. II. Medical perspectives].
Topics: Aspirin; Dinoprostone; Ductus Arteriosus, Patent; Humans; Immunity, Cellular; Indomethacin; Leukocytes; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E | 1986 |
Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Platelets; Drug Evaluation; Drug Interactions; Humans; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Kinetics; Naproxen; Osteoarthritis; Pain; Propionates; Prostaglandins; Rheumatic Diseases; Tissue Distribution | 1985 |
Prevention of cecitis in hamsters by certain prostaglandins.
Topics: Animals; Aspirin; Castor Oil; Cecal Diseases; Clindamycin; Cricetinae; Indomethacin; Inflammation; Magnesium Sulfate; Oils; Peanut Oil; Plant Oils; Prostaglandins, Synthetic; Sodium Salicylate | 1985 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colitis; Digestive System; Esophagus; Female; Humans; Ibuprofen; Indomethacin; Liver; Male; Middle Aged; Pancreatitis; Phenylbutazone; Propionates; Sialadenitis | 1985 |
Modern management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Counseling; Delayed-Action Preparations; Hospitalization; Humans; Indomethacin; Pain; Physical Therapy Modalities; Prognosis | 1985 |
[Effect of some drugs in the development and exacerbation of gastric and duodenal ulcer].
Topics: Adrenocorticotropic Hormone; Aspirin; Caffeine; Catecholamines; Duodenal Ulcer; Fluorouracil; Glucocorticoids; Histamine; Humans; Hypoglycemic Agents; Indomethacin; Parasympathomimetics; Phenylbutazone; Quinolines; Reserpine; Stomach Ulcer | 1974 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine; Exercise Therapy; Fever; Gold; Heart Failure; Home Care Services; Humans; Hypersensitivity; Indomethacin; Joints; Leukemia; Lupus Erythematosus, Systemic; Myocarditis; Pericarditis; Phenylbutazone; Prednisone; Prognosis; Purpura; Radiography; Rubella; Serum Sickness; Skin Manifestations; Splints; Synovial Fluid; Synovitis; Uveitis, Anterior; Vascular Diseases | 1971 |
[Gastric mucin].
Topics: Aspirin; Epithelial Cells; Epithelium; Gastric Juice; Gastric Mucins; Gastric Mucosa; Glycoproteins; Glycosaminoglycans; Granulation Tissue; Humans; Hydrogen-Ion Concentration; Indomethacin; Mucoproteins; Peptic Ulcer; Phenylbutazone; Regeneration | 1972 |
Gastric mucus and the gastric mucous barrier. A review.
Topics: Adrenocorticotropic Hormone; Aspirin; Eating; Fasting; Gastric Mucosa; Gastritis; Histamine; Humans; Hydrogen-Ion Concentration; Indomethacin; Mucus; Parathyroid Hormone; Peptic Ulcer; Phenylbutazone; Serotonin; Sympathetic Nervous System; Vagus Nerve | 1969 |
[Effect of some antirheumatic agents on the gastric mucous membrane].
Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dogs; Drug Hypersensitivity; Duodenal Ulcer; Esophageal Diseases; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Glucocorticoids; Humans; Hydrocortisone; Indomethacin; Intestinal Mucosa; Osteoarthritis; Penicillins; Phenylbutazone; Prednisolone; Rats; Rheumatic Diseases; Salicylates; Sodium Salicylate; Stomach Diseases; Stomach Ulcer; Streptomycin | 1971 |
Prostaglandins and cancer: an update.
Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; HeLa Cells; Humans; Hypercalcemia; In Vitro Techniques; Indomethacin; Neoplasms; Neoplasms, Experimental; Prostaglandins; Radioimmunoassay; Sarcoma; Thyroid Neoplasms | 1974 |
Medical management of the patient with arthritis.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Aspirin; Chondrocalcinosis; Colchicine; Drainage; Gold; Gout; Humans; Inclusion Bodies; Indomethacin; Mucins; Osteoarthritis; Phenylbutazone; Rest; Synovial Fluid; Uric Acid | 1974 |
[Biochemical mechanisms of the action of non-steroid anti-inflammatory agents (literature review)].
Topics: Adenosine Triphosphate; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Carboxy-Lyases; Chloroquine; Chymotrypsin; Glucose-6-Phosphate Isomerase; Histamine; Histidine; Indomethacin; Kallidin; Kinins; Lactates; Mefenamic Acid; Oxidative Phosphorylation; Peptide Hydrolases; Phenacetin; Phenylbutazone; Quinolines; Rats; Sodium Salicylate | 1972 |
The use of radioisotopes in normal and diseased joints.
Topics: Arthritis; Aspirin; Chromium Isotopes; Gold Isotopes; Histamine; Histamine H1 Antagonists; Humans; Indomethacin; Injections, Intra-Articular; Injections, Intravenous; Isoproterenol; Joint Diseases; Placebos; Prednisolone; Propranolol; Radioisotopes; Radionuclide Imaging; Regional Blood Flow; Serum Albumin, Radio-Iodinated; Sodium Isotopes; Synovial Membrane; Technetium; Xenon | 1972 |
Non-narcotic analgesics--their use and abuse.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Dextropropoxyphene; Drug Synergism; Flufenamic Acid; Humans; Indomethacin; Mefenamic Acid; Methotrimeprazine; Orphenadrine; Oxyphenbutazone; Pentazocine; Phenacetin; Phenylbutazone; Propionates; Tablets | 1972 |
The pathogenesis of asthma.
Topics: Acetaminophen; Adult; Affective Symptoms; Air Pollution; Aspirin; Asthma; Autonomic Nervous System; Cold Temperature; Dust; Humans; Indomethacin; Receptors, Adrenergic; Receptors, Cholinergic; Respiratory Tract Infections; Smoke; Sodium Salicylate; Sports | 1974 |
Prostaglandin E2 synthesis in human epidermis and its inhibition by unsaturated fatty acids.
Topics: Animals; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Deficiency Diseases; Fatty Acids, Essential; Fatty Acids, Unsaturated; Humans; Indomethacin; Linolenic Acids; Microsomes; Prostaglandins; Rats; Skin; Skin Diseases; Steroids; Structure-Activity Relationship; Subcellular Fractions | 1974 |
[Polymyalgia rheumatica (comprehensive review)].
Topics: Age Factors; Aspirin; Blood Protein Electrophoresis; Blood Sedimentation; Diagnosis, Differential; Giant Cell Arteritis; Humans; Indomethacin; Polymyalgia Rheumatica; Prednisone; Respiratory Tract Diseases; Vascular Diseases | 1973 |
[Clinical use of non-steroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Migration Inhibition; Chemotaxis; Collagen Diseases; Disease Models, Animal; Flufenamic Acid; Humans; Immunoglobulins; Indomethacin; Inflammation; Leukocytes; Mefenamic Acid; Phagocytosis; Synovial Fluid | 1974 |
Inhibition of prostaglandin biosynthesis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cats; Cattle; Depression, Chemical; Dogs; Fatty Acids; Fever; Guinea Pigs; Humans; Indomethacin; Inflammation; Mice; Microsomes; Mixed Function Oxygenases; Organ Specificity; Oxygen Consumption; Pain; Prostaglandins; Rabbits; Rats | 1974 |
Pharmacological properties of naproxen.
Topics: Administration, Oral; Administration, Topical; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Forssman Antigen; Granuloma; Guinea Pigs; Hydrocortisone; Indomethacin; Methyl Ethers; Morphine; Naphthalenes; Otitis; Phenylbutazone; Propionates; Rats; Respiration | 1973 |
Juvenile rheumatoid arthritis.
Topics: Antibodies, Antinuclear; Antimalarials; Arthritis, Juvenile; Aspirin; Blood Sedimentation; Child; Complement System Proteins; Cortisone; Diagnosis, Differential; Female; Gold; Humans; Immunoglobulins; Indomethacin; Latex Fixation Tests; Lupus Erythematosus, Systemic; Phenylbutazone | 1974 |
Letter: Prostaglandins and catecholamines in gonadotropin secretion.
Topics: Animals; Aspirin; Blood Platelets; Catecholamines; Depression, Chemical; Dopamine; Female; Gonadotropins; Humans; Hypothalamus; Indomethacin; Luteinizing Hormone; Ovary; Ovulation; Phenoxybenzamine; Pituitary Gland; Progesterone; Prostaglandins; Rabbits; Radioimmunoassay; Rats; Stimulation, Chemical; Uterus | 1974 |
Prostaglandins in the control of ovulation, corpus luteum function, and parturition.
Topics: Animals; Aspirin; Corpus Luteum; Cricetinae; Estrogens; Female; Haplorhini; Humans; Hysterectomy; Indomethacin; Labor, Induced; Luteinizing Hormone; Ovulation; Pregnancy; Progesterone; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Sheep | 1973 |
A critical appraisal of therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Aspirin; Flufenamic Acid; Gold; Humans; Indomethacin; Mefenamic Acid; Phenylbutazone; Physical and Rehabilitation Medicine | 1968 |
Advances in the treatment of rheumatic disorders.
Topics: Alkylating Agents; Allopurinol; Analgesics; Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Arthroplasty; Aspirin; Gold; Gout; Humans; Immunosuppressive Agents; Indomethacin; Phenacetin; Polymyalgia Rheumatica; Prednisolone; Prednisone; Rheumatic Fever; Synovitis | 1968 |
Ankylosing spondylitis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Humans; Indomethacin; Male; Phenylbutazone; Physical Examination; Physical Therapy Modalities; Radiography; Spondylitis, Ankylosing | 1970 |
Rheumatoid arthritis. Medical management.
Topics: Arthritis, Rheumatoid; Aspirin; Diet; Gold; Humans; Hydrocortisone; Immunosuppressive Agents; Indomethacin; Phenylbutazone; Physical Therapy Modalities; Prednisolone; Prednisone; Rest; Splints | 1970 |
Ibuprofen. A review.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Dyspepsia; Humans; Indomethacin; Osteoarthritis; Peptic Ulcer; Propionates | 1971 |
[Present position of the toxicology of drugs].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amantadine; Aminopterin; Animals; Animals, Newborn; Aspirin; Carcinogens; Codeine; Dogs; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fertility; Haplorhini; Humans; Indomethacin; Male; Meclizine; Methods; Mice; Morphine; Mutation; Nalidixic Acid; Neoplasms; Neoplasms, Experimental; Pharmacogenetics; Pregnancy; Pregnancy Complications; Rabbits; Rats; Reproduction; Sex Factors; Statistics as Topic; Time Factors | 1970 |
Prostaglandins and aspirin.
Topics: Aspirin; Depression, Chemical; Drug Antagonism; Humans; Indomethacin; Prostaglandin Antagonists; Prostaglandins | 1971 |
Drug treatment of allergic gastroenteritis.
Topics: Adult; Allergens; Antibody-Producing Cells; Antidiarrheals; Antigen-Antibody Reactions; Aspirin; Diarrhea; Digestive System; Female; Food Hypersensitivity; Gastroenteritis; Humans; Immunoglobulin E; Indomethacin; Mast Cells; Models, Biological; Prostaglandins; Sulfasalazine | 1980 |
Pharmacologic problems in shock research.
Topics: Adrenergic alpha-Antagonists; Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Indomethacin; Shock | 1983 |
Adjuvant drug therapy for decompression sickness: a review.
Topics: Adrenal Cortex Hormones; Animals; Anti-Arrhythmia Agents; Aspirin; Bronchodilator Agents; Coumarins; Cyproheptadine; Decompression Sickness; Dextrans; Diazepam; Dipyridamole; Fluid Therapy; Heparin; Humans; Indomethacin; Levodopa; Niacin; Vasoconstrictor Agents; Vasodilator Agents | 1982 |
Chemistry, measurement, and clinical significance of platelet specific proteins.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Cerebrovascular Disorders; Coronary Disease; Cytoplasmic Granules; Diabetes Mellitus; Heart Valve Diseases; Humans; Indomethacin; Kidney; Molecular Weight; Peptides; Platelet Factor 4; Radioimmunoassay; Thrombophlebitis; Vascular Diseases | 1982 |
Pharmacology of platelet-affecting drugs.
Topics: Animals; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Female; Heparin; Humans; Indomethacin; Male; Papio; Phospholipases; Platelet Adhesiveness; Platelet Function Tests; Rabbits; Sulfinpyrazone; Thrombin; Thromboembolism; Thrombosis; Thromboxane-A Synthase; Vasoconstriction; Ventricular Fibrillation | 1980 |
Control of vascular responsiveness during human pregnancy.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hypertension; Indomethacin; Muscle, Smooth, Vascular; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Prostaglandins; Theophylline | 1980 |
Review: prostaglandins in diarrheal states.
Topics: Aspirin; Bacterial Infections; Child; Cholera Toxin; Colonic Diseases; Cyclic AMP; Diarrhea; Dinoprostone; Female; Humans; Indomethacin; Pregnancy; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E | 1981 |
Prostaglandins and nonsteroidal antiinflammatory drugs in dysmenorrhea.
Topics: Anti-Inflammatory Agents; Aspirin; Contraceptives, Oral; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Phenylpropionates; Prostaglandins | 1983 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone | 1983 |
Nonsteroidal anti-inflammatory agents: species differences in pharmacodynamics.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Indomethacin; Kinetics; Meclofenamic Acid; Phenylbutazone; Species Specificity; Veterinary Medicine | 1983 |
Gastroduodenal damage due to drugs, alcohol and smoking.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal Hemorrhage; Glucocorticoids; Humans; Indomethacin; Intestinal Mucosa; Peptic Ulcer; Phenylbutazone; Recurrence; Smoking | 1984 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract].
Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases | 1984 |
Mechanisms of action: aspirin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes | 1983 |
Novel anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Carboxylic Acids; Dapsone; Humans; Immunity; Indomethacin; Prostaglandin Antagonists; Rats; Tilorone | 1984 |
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac | 1981 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Cellular and molecular mechanism(s) of coronary flow regulation by adenosine.
Topics: Adenine Nucleotides; Adenosine; Animals; Aspirin; Carotid Arteries; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Hydrogen-Ion Concentration; Hypoxia; Indomethacin; Molecular Biology; Myocardium; Phosphates; Potassium; Prostaglandins; Receptors, Drug; Vasodilator Agents | 1980 |
Preterm parturition. Prostaglandin synthetase inhibitors.
Topics: Amniotic Fluid; Animals; Aspirin; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Flufenamic Acid; Guinea Pigs; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Labor, Obstetric; Macaca mulatta; Obstetric Labor, Premature; Pregnancy; Rats; Sheep; Uterine Contraction | 1981 |
[Control of implantation in rats and sows by peroral administration of prostaglandin synthetase inhibitors. 1. Theoretical aspects of control of implantation in swine].
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drug Implants; Embryo Implantation; Estrogens; Female; Indomethacin; Progesterone; Prostaglandins F; Rats; Swine | 1981 |
Prostaglandins, slow-reacting substances (leukotrienes) and the lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchi; Epoprostenol; Guinea Pigs; Humans; Indomethacin; Infant, Newborn; Lung; Lung Diseases, Obstructive; Prostaglandin-Endoperoxide Synthases; Prostaglandins; SRS-A; Thromboxanes | 1981 |
Current status of the etiology and management of dysmenorrhea in adolescence.
Topics: Adolescent; Aspirin; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Ovulation; Prostaglandin Antagonists; Prostaglandins; Uterine Contraction | 1982 |
Drug therapy: nonsteroidal antiinflammatory drugs (first of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Child; Drug Tolerance; Female; Gastric Mucosa; Gastritis; Humans; Indomethacin; Infant, Newborn; Inflammation; Kidney; Kinetics; Liver; Maternal-Fetal Exchange; Pregnancy; Prostaglandins; Salicylates; Stomach Ulcer | 1980 |
[The most common drugs considered harmful to the stomach, Clinical and endoscopic studies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Dyspepsia; Female; Gastric Juice; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Indomethacin; Male; Middle Aged; Peptic Ulcer; Phenylbutazone; Prostaglandins; Reserpine; Stomach; Stomach Diseases | 1980 |
Drug-induced peptic ulcer and upper gastrointestinal bleeding.
Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Aspirin; Diuretics; Emepronium; Female; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Middle Aged; Peptic Ulcer; Phenylbutazone; Potassium Chloride; Smoking; Spironolactone | 1980 |
Prostaglandins, macrophages, and immunity.
Topics: Arachidonic Acids; Aspirin; Cell Division; Cell Separation; Epoprostenol; Immunity, Cellular; Indomethacin; Inflammation; Lymphocytes; Lymphokines; Macrophages; Prostaglandins; Prostaglandins E; Thromboxane A2 | 1980 |
Adverse reactions of aspirin and related drugs.
Topics: Aspirin; Bronchial Spasm; Drug Hypersensitivity; Humans; Ibuprofen; Indomethacin; Prostaglandins; Urticaria | 1981 |
Acute effects of aspirin and acetaminophen on renal function.
Topics: Acetaminophen; Aspirin; Humans; Indomethacin; Kidney; Kidney Failure, Chronic; Liver Cirrhosis; Lupus Erythematosus, Systemic; Prostaglandins | 1981 |
Prostaglandins and the alpha-cell.
Topics: Albuterol; Animals; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Furosemide; Glucagon; Guinea Pigs; Humans; Indomethacin; Islets of Langerhans; Kinetics; Propranolol; Prostaglandins; Prostaglandins E; Rats | 1981 |
Prostaglandin inhibition and myocardial infarct size.
Topics: Acute Disease; Animals; Aspirin; Coronary Disease; Humans; Ibuprofen; Indomethacin; Models, Biological; Myocardial Infarction; Prognosis; Prostaglandin Antagonists; Prostaglandins | 1981 |
Combination use of nonsteroidal antiinflammatory drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Kinetics; Rats | 1981 |
Advances in treating cystoid macular edema.
Topics: Aspirin; Cryosurgery; Humans; Indomethacin; Light Coagulation; Macular Degeneration; Prostaglandins; Vitreous Body | 1981 |
Hyperuricemia and gout.
Topics: Allopurinol; Arthritis; Aspirin; Colchicine; Diuretics; Gout; Gout Suppressants; Humans; Indomethacin; Phenylbutazone; Uric Acid | 1982 |
The neurological basis of fever.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Fever; Humans; Indomethacin; Prostaglandins; Pyrogens | 1996 |
[Morphology of gastric mucosa lesions induced by nonsteroidal anti-inflammatory agents].
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Division; Gastric Mucosa; Gastritis, Atrophic; Humans; Indomethacin; Risk Factors | 1996 |
Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cerebral Hemorrhage; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Female; Hemorrhage; Humans; Indomethacin; Male; Mice; Middle Aged; Models, Biological; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rats | 1996 |
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage; Humans; Indomethacin; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Polycythemia Vera; Splenomegaly; Thermography; Thrombocytosis; Thrombosis | 1996 |
Use of carprofen for the treatment of pain and inflammation in dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles | 1997 |
[Neutrophil-endothelium interaction].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Adhesion; Cell Adhesion Molecules; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Gastric Mucosa; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Microcirculation; Neutrophils; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
[Reactive oxygen species and free radical reactions are involved in the pathogenesis of non-steroidal anti-inflammatory drugs-induced gastric mucosal injury].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Free Radicals; Gastric Mucosa; Humans; Indomethacin; Neutrophil Activation; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2002 |
Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins.
Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indomethacin; Intracranial Arteriosclerosis; Randomized Controlled Trials as Topic; Treatment Outcome; Vasculitis, Central Nervous System | 2004 |
Effects of cyclooxygenase inhibition on the gastrointestinal tract.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Etodolac; Gastrointestinal Tract; Humans; Indomethacin; Naproxen; Species Specificity | 2006 |
[Novel pharmacological effects of NSAIDs and their molecular mechanism].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Dinoprostone; Humans; Indomethacin; Neoplasms; Receptors, Prostaglandin E, EP4 Subtype; Stomach Ulcer | 2012 |
Pharmacogenetics of nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Humans; Ibuprofen; Indomethacin; Pharmacogenetics; Pyrazoles; Sulfonamides | 2012 |
Colchicine for pericarditis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colchicine; Humans; Ibuprofen; Indomethacin; Pericarditis; Randomized Controlled Trials as Topic; Recurrence | 2014 |
Phytochemicals enhance antioxidant enzyme expression to protect against NSAID-induced oxidative damage of the gastrointestinal mucosa.
Topics: Angiogenesis Inducing Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Aspirin; Diclofenac; Flavonoids; Gastric Mucosa; Gastrointestinal Tract; Humans; Indomethacin; Inflammation; Ketoprofen; Oxidative Stress; Phytochemicals; Protective Agents | 2017 |
Role of Sulforaphane in Protection of Gastrointestinal Tract Against H. pylori and NSAID-Induced Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis; Gastrointestinal Tract; Helicobacter Infections; Helicobacter pylori; Humans; Indomethacin; Intestinal Mucosa; Isothiocyanates; Mice; Oxidative Stress; Sulfoxides | 2017 |
Prevention of Prematurity: Advances and Opportunities.
Topics: Anti-Infective Agents; Aspirin; Cerclage, Cervical; Cesarean Section; Female; Humans; Indomethacin; Labor, Induced; Magnesium Sulfate; Nifedipine; Pharmacogenetics; Platelet Aggregation Inhibitors; Preconception Care; Pregnancy; Premature Birth; Progesterone; Progestins; Reproductive Techniques, Assisted; Smoking Cessation; Tocolytic Agents | 2018 |
Is Medication Overuse Drug Specific or Not? Data from a Review of Published Literature and from an Original Study on Italian MOH Patients.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disability Evaluation; Female; Headache Disorders, Secondary; Humans; Indomethacin; Italy; Male; Middle Aged; Migraine Disorders; Recurrence; Tramadol; Tryptamines | 2018 |
Gastroprotective Role of Fruit Extracts in Gastric Damage Induced by Non-Steroidal Anti-Inflammatory Drugs: A Systematic Review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Aspirin; Fruit; Gastric Mucosa; Indomethacin; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer | 2023 |
134 trial(s) available for aspirin and indomethacin
| Article | Year |
|---|---|
Long-term effects of alclofenac.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Penicillamine; Phenylacetates; Time Factors | 1976 |
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
The effects of aspirin, ethanol, indomethacin and 9alpha-fludrocortisone on buccal mucosal potential difference.
Topics: Adult; Aspirin; Cheek; Ethanol; Fludrocortisone; Humans; Hydrogen-Ion Concentration; Indomethacin; Membrane Potentials; Middle Aged; Mouth Mucosa; Pressure; Salivation; Stomatitis, Aphthous; Temperature | 1978 |
Prostaglandin-synthesis inhibitors in prophylaxis of food intolerance.
Topics: Acute Disease; Adult; Animals; Aspirin; Bivalvia; Chickens; Clinical Trials as Topic; Dairy Products; Eggs; Female; Food Hypersensitivity; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Male; Meat; Middle Aged; Prostaglandins E; Prostaglandins F; Swine; Zea mays | 1978 |
[Reduction of the effects of indomethacin by aspirin. Value of measurement of the articular index and sigma ESR].
Topics: Adult; Aspirin; Blood Sedimentation; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hematocrit; Humans; Indomethacin; Male; Middle Aged; Pain; Placebos; Rheumatic Diseases; Time Factors | 1977 |
The effect of a new non-steroidal anti-inflammatory agent, sulindac, on platelet function.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzylidene Compounds; Blood Platelets; Chromatography, Affinity; Clinical Trials as Topic; Humans; Indenes; Indomethacin; Platelet Aggregation; Serotonin | 1977 |
The effects of "anti-platelet" drugs on bleeding time and platelet aggregation in normal human subjects.
Topics: Aspirin; Blood Coagulation; Chlorpromazine; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Female; Fibrinolytic Agents; Guaifenesin; Humans; Indomethacin; Male; Platelet Aggregation; Time Factors | 1977 |
A comparison of naproxen, indomethacin and acetylsalicylic acid in pain after varicose vein surgery.
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Indomethacin; Middle Aged; Naproxen; Pain, Postoperative; Varicose Veins | 1978 |
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Middle Aged; Phenylbutazone; Placebos; Respiratory Function Tests; Sodium Salicylate; Spirometry; Tartrazine | 1978 |
Indomethacin in the treatment of primary dysmenorrhoea.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Indomethacin; Placebos; Time Factors | 1978 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prostaglandin Antagonists; Salicylates; Sheep | 1978 |
Prostaglandin-synthesis inhibition and exercise bronchospasm.
Topics: Aspirin; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; Indomethacin; Physical Exertion; Placebos; Prostaglandin Antagonists | 1978 |
Tolfenamic acid in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; ortho-Aminobenzoates; Phenylbutazone; Prednisone; Time Factors | 1979 |
[Pharmacokinetic interactions between nonsteroid antirheumatism agents].
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Indomethacin; Kinetics; Phenylbutazone | 1979 |
The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study.
Topics: Adult; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; Placebos | 1979 |
Prostaglandin biosynthesis inhibitors and endometriosis.
Topics: Aspirin; Double-Blind Method; Dysmenorrhea; Endometriosis; Female; Humans; Indomethacin; ortho-Aminobenzoates; Pelvic Neoplasms; Placebos; Prostaglandin Antagonists | 1979 |
Ultraviolet irradiation-induced inflammation: effects of steroid and nonsteroid anti-inflammatory agents.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Drug Evaluation; Drug Therapy, Combination; Erythema; Female; Humans; Indomethacin; Male; Skin Diseases; Ultraviolet Rays | 1979 |
Quantifications of the major urinary metabolite of the E prostaglandins by mass spectrometry: evaluation of the method's application to clinical studies.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Child; Child, Preschool; Chromatography, Gas; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Mass Spectrometry; Middle Aged; Prostaglandins E; Sex Factors | 1976 |
A new (?) Clinical headache entity "chronic paroxysmal hemicrania" 2.
Topics: Affective Symptoms; Aspirin; Cerebrovascular Circulation; Chronic Disease; Clinical Trials as Topic; Cornea; Diagnosis, Differential; Female; Headache; Histamine; Humans; Indomethacin; Ketoprofen; Kininogens; Kinins; Middle Aged; Migraine Disorders; Prednisone; Prostaglandins E | 1976 |
Ketoprofen - clinical efficacy.
Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Gout; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Placebos; Sciatica; Spondylitis, Ankylosing | 1976 |
Clinical and objective assessments of naproxen through 5 years of clinical experience.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chronic Disease; Clinical Trials as Topic; Female; Follow-Up Studies; Gout; Humans; Indomethacin; Long-Term Care; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Placebos; Polymyalgia Rheumatica | 1975 |
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, Combination; Ergotamine; Headache; Histamine; Humans; Indomethacin; Metergoline; Methysergide; Migraine Disorders; Pizotyline; Prochlorperazine; Reserpine; Retrospective Studies; Urea | 1975 |
The effect of aspirin and indomethacin on the TRH response in man.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Male; Pituitary Gland; Prolactin; Prostaglandins A; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1976 |
Effects of acetylsalicylic acid and indomethacin on growth hormone secretion in man.
Topics: Adult; Aspirin; Blood Glucose; Fatty Acids, Nonesterified; Female; Growth Hormone; Humans; Indomethacin; Male; Middle Aged; Placebos; Prostaglandins | 1977 |
[Side effects following ingestion of non-steroid anti-inflammatory agents].
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Hallucinations; Humans; Indomethacin; Joint Diseases; Mefenamic Acid; Middle Aged; Placebos; Pyrazines | 1975 |
[Clinical experiences with Voltaren a new nonsteroid antirheumatic agent].
Topics: Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Drug Evaluation; Drug Tolerance; Humans; Indomethacin; Nausea; Phenylacetates | 1975 |
Indomethacin--aspirin interaction: a clinical appraisal.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Interactions; Humans; Indomethacin; Inflammation; Middle Aged; Placebos | 1975 |
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Fluorobenzenes; Flurbiprofen; Humans; Indomethacin; Mefenamic Acid; Pain; Phenylpropionates; Placebos; Prednisone; Propionates | 1975 |
The levels of serum growth hormone and immunoreactive insulin after administration of antipyretic analgetics.
Topics: Adolescent; Adult; Aspirin; Blood Glucose; Clinical Trials as Topic; Growth Hormone; Humans; Indomethacin; Insulin; Male; Phenylbutazone; Placebos; Time Factors | 1975 |
A comparison of micro-encapsulated aspirin and indomethacin in the treatment of rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Capsules; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Indomethacin; Male; Middle Aged | 1975 |
Therapeutic effectiveness of paracetamol in rheumatoid arthritis.
Topics: Acetaminophen; Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Female; Humans; Indomethacin; Infant, Newborn; Placebos; Prednisone; Pregnancy | 1975 |
Antiplatelet drugs and generation of thrombin in clotting blood.
Topics: Adult; Aspirin; Blood Coagulation; Female; Fibrinopeptide A; Humans; In Vitro Techniques; Indomethacin; Kinetics; Male; Mathematics; Methacrylates; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors; Skin; Thrombin; Thromboxane-A Synthase; Ticlopidine | 1992 |
Protective activity of inhaled nonsteroidal antiinflammatory drugs on bronchial responsiveness to ultrasonically nebulized water.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchi; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Indomethacin; Male; Middle Aged; Ultrasonics; Water | 1992 |
A new topical treatment for acute herpetic neuralgia and post-herpetic neuralgia: the aspirin/diethyl ether mixture. An open-label study plus a double-blind controlled clinical trial.
Topics: Acute Disease; Administration, Topical; Adult; Aged; Aspirin; Diclofenac; Double-Blind Method; Drug Combinations; Ether; Female; Follow-Up Studies; Herpes Zoster; Humans; Indomethacin; Male; Middle Aged; Neuralgia; Skin Diseases | 1992 |
Different interactions of platelets with arterial and venous coronary bypass vessels.
Topics: Apyrase; Arginine; Aspirin; Blood Platelets; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Isometric Contraction; Ketanserin; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Platelet Aggregation; Saphenous Vein; Thromboxane A2 | 1991 |
Processing and statistical analysis of laser Doppler data applied to the assessment of systemic anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dermatitis, Contact; Female; Humans; Indomethacin; Male; Nicotinic Acids; Propionates; Skin; Vasodilation | 1991 |
Analgesic and antiinflammatory effects of glucamethacin (a nonsteroidal antiinflammatory analgesic) after the removal of impacted third molars.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Double-Blind Method; Edema; Female; Humans; Indomethacin; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Tooth, Impacted; Trismus | 1990 |
Prevention of non-steroidal anti-inflammatory agents induced acute gastric mucosal lesions by carbonic anhydrase inhibitors. An endoscopic study.
Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Phenylbutazone; Random Allocation; Stomach Ulcer | 1989 |
Randomized trial of recombinant alpha 2b-interferon with or without indomethacin in patients with metastatic malignant melanoma.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Female; Humans; Indomethacin; Interferon Type I; Killer Cells, Natural; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Random Allocation; Recombinant Proteins | 1989 |
Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Cyclooxygenase Inhibitors; Hemostasis; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase | 1987 |
Inhibition of arachidonic acid metabolism in the perinatal period: pharmacology, clinical application, and potential adverse effects.
Topics: Administration, Oral; Arachidonic Acid; Arachidonic Acids; Aspirin; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus, Patent; Female; Hemodynamics; Humans; Indomethacin; Maternal-Fetal Exchange; Obstetric Labor, Premature; Platelet Aggregation; Pregnancy; Pulmonary Circulation; Random Allocation; Uterine Contraction | 1986 |
[Stomach tolerance of nonsteroidal antirheumatic drugs: comparative endoscopic study].
Topics: Adult; Alprostadil; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Gastroscopy; Humans; Indomethacin; Misoprostol; Omeprazole; Prostaglandins E; Ranitidine; Rioprostil; Stomach Ulcer | 1987 |
Effect in man of aspirin, standard indomethacin, and sustained release indomethacin preparations on gastric bleeding.
Topics: Adolescent; Adult; Aspirin; Delayed-Action Preparations; Female; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Orosomucoid | 1988 |
Piroxicam in acute musculoskeletal disorders and sports injuries.
Topics: Activities of Daily Living; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Athletic Injuries; Bone Diseases; Child; Clinical Trials as Topic; Humans; Indomethacin; Middle Aged; Muscular Diseases; Naproxen; Pain; Piroxicam | 1988 |
[Comparative, double blind study of the analgesic and anti-inflammatory activity of glucamethacin (Indicin), aspirin and placebo in oral surgery].
Topics: Adult; Aspirin; Double-Blind Method; Female; Humans; Indomethacin; Male; Molar, Third; Pain, Postoperative; Tooth Extraction; Tooth, Impacted | 1987 |
Diphenpyramide: a review of its pharmacology and anti-inflammatory effects.
Topics: Absorption; Acetamides; Administration, Oral; Adolescent; Adult; Aged; Animals; Arthritis; Aspirin; Biotransformation; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Infant; Kinetics; Male; Middle Aged; Muscular Diseases; Phenylbutazone; Platelet Aggregation | 1986 |
A comparison of the incidence of peptic ulceration for fenbufen, indomethacin and aspirin treated patients compared with the general population.
Topics: Actuarial Analysis; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Information Systems; Peptic Ulcer; Phenylbutyrates; Propionates; Risk; Time Factors; United States | 1986 |
International experience with diclofenac in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
The effect of acetyl salicylic acid and indomethacin on cell proliferation kinetics in the human gastric mucosa.
Topics: Adult; Aspirin; Cell Differentiation; Double-Blind Method; Female; Gastric Fundus; Gastric Mucosa; Humans; Indomethacin; Kinetics; Male; Pyloric Antrum | 1987 |
Protective effect of sucralfate against aspirin-induced damage to the human gastric mucosa.
Topics: Aspirin; Drug Evaluation; Drug Interactions; Gastric Mucosa; Gastroscopy; Humans; Indomethacin; Random Allocation; Sucralfate | 1987 |
Gastric irritation of oxaprozin, a new nonsteroidal, antiinflammatory drug, in comparison to acetylsalicylic acid and indomethacin: a gastric potential difference analysis.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis; Humans; Indomethacin; Male; Membrane Potentials; Oxaprozin; Propionates; Random Allocation | 1987 |
[Effect of FCE 20,700, an effective oral prostaglandin E2 analog on the human gastric mucosa epithelium].
Topics: Administration, Oral; Adult; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Epithelium; Gastric Acid; Gastric Mucosa; Gastroscopy; Humans; Indomethacin; Male; Membrane Potentials; Pentagastrin; Prostaglandins E, Synthetic; Random Allocation | 1986 |
Clinical perspectives in rheumatology: a review of three common forms of arthritis and results of United States trials with isoxicam.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Osteoarthritis; Piroxicam; Spondylitis, Ankylosing; Thiazines | 1985 |
Evaluation of the safety of isoxicam.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Gastrointestinal Diseases; Hip Joint; Humans; Indomethacin; Joint Diseases; Knee Joint; Middle Aged; Piroxicam; Safety; Thiazines | 1985 |
Double-blind preference and compliance multicentre study in osteoarthritis: once-a-day treatment.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration Schedule; Humans; Indomethacin; Indoprofen; Ketoprofen; Middle Aged; Naproxen; Osteoarthritis; Pain; Patient Compliance; Piroxicam; Thiazines | 1985 |
Effects of indomethacin on systemic and coronary hemodynamics in patients with coronary artery disease.
Topics: Adult; Aspirin; Blood Pressure; Coronary Circulation; Coronary Disease; Cyclooxygenase Inhibitors; Female; Heart Rate; Hemodynamics; Humans; Indomethacin; Male; Middle Aged; Prostaglandins; Vascular Resistance | 1985 |
Aspirin, indomethacin and dazoxiben do not affect the fibrinolytic activation induced by venous occlusion.
Topics: Aspirin; Double-Blind Method; Fibrinolysis; Humans; Imidazoles; Indomethacin; Male; Prostaglandins; Serum Globulins; Tissue Plasminogen Activator; Vascular Diseases; Veins | 1985 |
Effect of aspirin and indomethacin on exercise-induced changes in blood pressure and limb blood flow in normal volunteers.
Topics: Adult; Aspirin; Blood Pressure; Double-Blind Method; Extremities; Forearm; Humans; Indomethacin; Leg; Male; Physical Exertion; Regional Blood Flow; Time Factors | 1985 |
Prostaglandins and nicotinate-provoked increase in cutaneous blood flow.
Topics: Administration, Oral; Administration, Topical; Adult; Aspirin; Double-Blind Method; Doxepin; Drug Interactions; Erythema; Female; Humans; Ibuprofen; Indomethacin; Male; Nicotinic Acids; Prostaglandins; Random Allocation; Skin; Structure-Activity Relationship; Vasodilation | 1985 |
Evaluation of indomethacin by a controlled, cross-over technique in 30 patients with ankylosing spondylitis.
Topics: Alkaline Phosphatase; Anemia, Hypochromic; Aspartate Aminotransferases; Aspirin; Central Nervous System Diseases; Clinical Trials as Topic; Drug Eruptions; Drug Hypersensitivity; gamma-Globulins; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Phenylbutazone; Placebos; Spondylitis, Ankylosing; Steroids; Vertigo | 1967 |
Treatment of juvenile rheumatoid arthritis -- a world survey.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Australia; Clinical Trials as Topic; Drug Therapy, Combination; Egypt; Europe; Fever; Gold Sodium Thiomalate; Humans; Immunosuppressive Agents; Indomethacin; Japan; New Zealand; Phenylbutazone; Surveys and Questionnaires; Synovectomy; United States | 1974 |
[Anti-inflammatory treatment of lumbago?].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Back Pain; Female; Humans; Indomethacin; Male; Middle Aged; Placebos | 1970 |
Mefenamic acid in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged; ortho-Aminobenzoates; Phenylbutazone; Placebos; Prednisolone | 1967 |
An analgesic combination.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Drug Combinations; Family Practice; Female; Humans; Indomethacin; Male; Middle Aged; Rheumatic Diseases | 1973 |
Effect of concurrent administration of aspirin and indomethacin on serum concentrations.
Topics: Administration, Oral; Adult; Analysis of Variance; Aspirin; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Methods; Salicylates; Spectrometry, Fluorescence; Suppositories; Time Factors | 1974 |
Evaluation of the therapeutic potential of ketoprofen in rheumatoid arthritis.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzophenones; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Indomethacin; Phenylpropionates; Placebos; Prednisone; Propionates; Statistics as Topic | 1974 |
A multicentre trial of Voltaren in the treatment of rheumatoid Arthritis.
Topics: Adult; Aged; Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Aged; Phenylacetates; Placebos | 1974 |
A profile of the physiological disposition and gastro-intestinal effects of fenoprofen in man.
Topics: Administration, Oral; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Biotransformation; Child; Clinical Trials as Topic; Drug Interactions; Gastrointestinal Diseases; Humans; Indomethacin; Injections, Intravenous; Phenobarbital; Phenyl Ethers; Phenylpropionates; Placebos; Protein Binding; Rats | 1974 |
[Do parenterally administered anti-prostaglandins have an action on the ocular pressure?].
Topics: Acetazolamide; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Intraocular Pressure; Placebos; Prostaglandin Antagonists; Salicylates; Sodium Salicylate | 1972 |
Effect of several drugs on gastric potential difference in man.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Drug Combinations; Drug Synergism; Ethanol; Female; Gastric Mucosa; Humans; Indomethacin; Male; Membrane Potentials; Phenylbutazone; Prednisone | 1974 |
Knee joint temperatures during the use of anti-inflammatory drugs.
Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Body Temperature; Depression, Chemical; Humans; Hydrocortisone; Indomethacin; Injections, Intra-Articular; Knee Joint; Phenylbutazone; Stimulation, Chemical; Temperature; Thermography | 1974 |
Indomethacin and acetylsalicylic acid in the treatment of osteoarthritis of the hips and knees.
Topics: Aged; Aspirin; Clinical Trials as Topic; Hip Joint; Humans; Indomethacin; Knee Joint; Male; Middle Aged; Osteoarthritis | 1969 |
Indomethacin in the management of erythema nodosum leprosum--a double-blind controlled trial.
Topics: Adolescent; Adult; Aspirin; Chloroquine; Clinical Trials as Topic; Erythema Nodosum; Humans; Indomethacin; Leprosy; Prednisolone | 1969 |
Assessment of clinical methods of evaluation and isotope techniques in analgesic trials in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Placebos; Radioisotopes; Technetium; Xenon | 1970 |
Statistical approach to indices of disease activity in rheumatoid arthritis.
Topics: Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as Topic; Fatigue; Humans; Indomethacin; Methods; Movement; Pain; Phenylbutazone; Placebos; Statistics as Topic | 1971 |
Ibuprofen. A review.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Dyspepsia; Humans; Indomethacin; Osteoarthritis; Peptic Ulcer; Propionates | 1971 |
Modification by drugs of urinary fibrin/fibrinogen degradation products in glomerulonephritis.
Topics: Adolescent; Adult; Aged; Aspirin; Child; Creatinine; Female; Fibrin; Fibrinogen; Glomerulonephritis; Humans; Indomethacin; Kidney Glomerulus; Male; Middle Aged; Plasminogen; Prednisone; Proteinuria; Time Factors; Urea | 1972 |
Indomethacin in in-patient treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Humans; Indomethacin; Male | 1966 |
Relative efficacy of indomethacin and acetylsalicylic acid in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Aged | 1967 |
Effect of drugs on urate binding to plasma proteins.
Topics: Adult; Allopurinol; Arthritis; Aspirin; Blood Proteins; Chromatography, DEAE-Cellulose; Colchicine; Female; Gout; Humans; Indomethacin; Male; Phenylbutazone; Probenecid; Protein Binding; Sulfinpyrazone; Uric Acid | 1969 |
Effect of non-steroidal anti-inflammatory drugs on osteoarthritis of the knee. With special reference to PSP clearance as an indicator.
Topics: Aspirin; Humans; Indomethacin; Inflammation; Knee Joint; Osteoarthritis; Phenylbutazone; Physical Therapy Modalities; Time Factors | 1970 |
Influence of indometacin and acetylsalicylic acid on the therapeutic effectiveness of talinolol in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Indomethacin; Male; Middle Aged; Propanolamines | 1984 |
Prostaglandins and endometriosis.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Clinical Trials as Topic; Endometriosis; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Piroxicam vs. aspirin and indomethacin: efficacy, safety, and compliance in osteoarthritis and rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Humans; Indomethacin; Osteoarthritis; Patient Compliance; Piroxicam; Thiazines | 1983 |
Overview of efficacy of fenbufen in rheumatoid arthritis and osteoarthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Osteoarthritis; Phenylbutyrates; Placebos; Propionates; Risk; Time Factors | 1983 |
Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Epoprostenol; Female; Humans; Indomethacin; Ovarian Neoplasms; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Effects of indomethacin, sulindac, naproxen, aspirin, and paracetamol in treated hypertensive patients.
Topics: Acetaminophen; Aldosterone; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hypertension; Indenes; Indomethacin; Naproxen; Placebos; Random Allocation; Renin; Sodium; Sulindac; Time Factors | 1984 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Regional Blood Flow; Thiazines | 1983 |
Asthma relieved by acetylsalicylic acid and nonsteroid anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Dipyrone; Female; Forced Expiratory Volume; Humans; Indomethacin; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazolones; Respiratory Function Tests | 1984 |
Medicines of choice in low back pain.
Topics: Acetaminophen; Aspirin; Back Pain; Dextropropoxyphene; Female; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged; Phenylbutazone | 1980 |
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac | 1981 |
Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Buffers; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged; Naproxen; Time Factors; Tolmetin | 1984 |
Diflunisal protects human gastric mucosa against damage by indomethacin.
Topics: Adult; Aspirin; Diflunisal; Dinoprostone; Female; Gastric Mucosa; Humans; Indomethacin; Male; Membrane Potentials; Prostaglandins E; Salicylates | 1983 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Protective effect of acetaminophen against aspirin- and ethanol-induced damage to the human gastric mucosa.
Topics: Acetaminophen; Administration, Oral; Adult; Aspirin; Drug Evaluation; Ethanol; Female; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Indomethacin; Ion Exchange; Male; Potentiometry; Prostaglandin Antagonists; Sodium; Time Factors | 1984 |
Non-steroidal anti-inflammatory drugs and blood pressure.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Blood Pressure Determination; Body Weight; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Plasma Volume; Posture; Random Allocation; Renin | 1982 |
Influence of indomethacin and aspirin on the vesicosphincteric dynamics of prostatectomized patients.
Topics: Aspirin; Cyclooxygenase Inhibitors; Humans; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostatectomy; Urethra; Urinary Bladder; Urodynamics | 1982 |
Effect of antiinflammatory drugs on the phagocytic activity of peripheral blood monocytes.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Female; Flufenamic Acid; Humans; Indomethacin; Listeria monocytogenes; Male; Middle Aged; Monocytes; Phagocytosis; Phenylbutazone; Sulindac | 1982 |
Indomethacin but not aspirin increases plasma lithium ion levels.
Topics: Adult; Aspirin; Creatinine; Delayed-Action Preparations; Drug Interactions; Female; Humans; Indomethacin; Kidney; Lithium; Potassium; Prostaglandins E; Sodium | 1983 |
[Stomach tolerance of non-steroid anti-rheumatic agents. Studies on gastric irritation caused by carprofen in comparison with acetylsalicyclic acid, indomethacin, piroxicam, and diclofenac].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Diclofenac; Gastric Mucosa; Humans; Indomethacin; Male; Phenylacetates; Piroxicam; Thiazines | 1982 |
Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Indomethacin; Melena; Naproxen; Propionates; Prostaglandins; Sulindac; Time Factors | 1980 |
Meclofenamate sodium (meclomen) a new antiarthritic agent.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Meclofenamic Acid; ortho-Aminobenzoates; Osteoarthritis | 1980 |
Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Arteries; Aspirin; Clinical Trials as Topic; Coronary Circulation; Coronary Vessels; Double-Blind Method; Female; Humans; Indomethacin; Ischemia; Male; Middle Aged; Recurrence; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors; Veins | 1981 |
Additive clinical effect of indomethacin suppositories during salicylate therapy in rheumatoid patients.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Prostaglandins F; Suppositories | 1981 |
A comparison of the effects of HP 549 (Isoxepac), indomethacin and acetylsalicylic acid (Aspirin) on gastric mucosa in man.
Topics: Acetates; Adult; Aspirin; Clinical Trials as Topic; Dibenzoxepins; Double-Blind Method; Female; Gastric Mucosa; Gastritis; Gastroscopy; Humans; Indomethacin; Male | 1981 |
Activated osteoarthrosis (osteoarthritis) and its treatment with indomethacin and benoxaprofen: a double-blind crossover study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Propionates | 1982 |
Night-time indomethacin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Indomethacin; Middle Aged | 1982 |
Therapy of symptomatic pericarditis after myocardial infarction: retrospective and prospective studies of aspirin, indomethacin, prednisone, and spontaneous resolution.
Topics: Adult; Aged; Aspirin; Dextropropoxyphene; Female; Humans; Indomethacin; Male; Middle Aged; Myocardial Infarction; Pericarditis; Prednisone; Prospective Studies; Retrospective Studies; Time Factors | 1981 |
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Double-Blind Method; Drug Synergism; Female; Forced Expiratory Volume; Furosemide; Humans; Indomethacin; Lysine; Male; Middle Aged | 1993 |
[Antipyretic effect of indomethacin vs aspirin in fever of tumor origin].
Topics: Aspirin; Body Temperature; Female; Fever; Humans; Indomethacin; Male; Middle Aged; Neoplasms | 1993 |
Cyclooxygenase inhibitors acetylsalicylic acid and indomethacin do not affect capsaicin-induced neurogenic inflammation in human skin.
Topics: Adult; Aspirin; Blood Flow Velocity; Capsaicin; Cyclooxygenase Inhibitors; Dermatitis, Contact; Double-Blind Method; Female; Humans; Indomethacin; Male; Prostaglandins; Skin | 1993 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Hungary; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Risk Factors; Sweden; United States | 1993 |
Aspirin versus indomethacin treatment of patent ductus arteriosus in preterm infants with respiratory distress syndrome.
Topics: Aspirin; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Logistic Models; Prospective Studies; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 1995 |
Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skin.
Topics: Acidosis; Administration, Topical; Adult; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Humans; Indomethacin; Injections, Intradermal; Isotonic Solutions; Male; Middle Aged; Palliative Care; Pressure; Salicylates; Salicylic Acid; Skin Diseases | 1995 |
Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Indomethacin; Lung; Lysine; Male; Middle Aged; Osmolar Concentration; Sodium Salicylate; Sulfites | 1996 |
Topical aspirin/diethyl ether mixture versus indomethacin and diclofenac/diethyl ether mixtures for acute herpetic neuralgia and postherpetic neuralgia: a double-blind crossover placebo-controlled study.
Topics: Acute Disease; Administration, Cutaneous; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Double-Blind Method; Ether; Female; Herpes Zoster Oticus; Humans; Indomethacin; Male; Middle Aged; Neuralgia; Pain Measurement; Solvents | 1996 |
Comparative study of the efficacy of lysine acetylsalicylate, indomethacin and pethidine in acute renal colic.
Topics: Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colic; Double-Blind Method; Female; Humans; Indomethacin; Kidney Diseases; Lysine; Male; Meperidine; Middle Aged; Pain Measurement; Time Factors | 1996 |
Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cimetidine; Cross-Over Studies; Double-Blind Method; Duodenal Ulcer; Female; Fibroblast Growth Factor 2; Humans; Indomethacin; Male; Models, Biological; Recurrence; Stomach Ulcer | 1997 |
Prevention of heterotopic ossification after total hip replacement. A prospective, randomised study using acetylsalicylic acid, indomethacin and fractional or single-dose irradiation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Hip Prosthesis; Humans; Indomethacin; Male; Middle Aged; Ossification, Heterotopic; Postoperative Complications; Postoperative Period; Prospective Studies; Radiotherapy Dosage | 1997 |
[Heterotopic ossifications].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthrography; Arthroplasty, Replacement, Hip; Aspirin; Combined Modality Therapy; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indomethacin; Male; Middle Aged; Ossification, Heterotopic; Postoperative Complications; Prospective Studies; Radiotherapy Dosage; Risk Factors | 1997 |
Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Indomethacin; Lysine; Male; Sodium Salicylate | 1999 |
[Antihypertensive effect of enalapril and lisinopril administered in combination with nonsteroid anti-inflammatory agents].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Drug Antagonism; Enalapril; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Lisinopril; Male; Middle Aged; Osteochondritis | 2001 |
UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Double-Blind Method; Drug Combinations; Erythema; Female; Histamine H1 Antagonists; Humans; Indomethacin; Interleukin-1; Interleukin-6; Keratinocytes; Skin; Sunburn; Time Factors; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2001 |
Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Aspirin; Blood Platelets; Citrulline; Cyclooxygenase Inhibitors; Drug Administration Schedule; Female; Humans; Indomethacin; Isoproterenol; Male; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors | 2003 |
Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Coronary Artery Bypass; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Activation; Humans; Indomethacin; Isoenzymes; Membrane Proteins; P-Selectin; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyridines; Thromboxane-A Synthase; Thromboxanes; Time Factors | 2003 |
The renal effects of the addition of low-dose aspirin to COX-2 selective and nonselective antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Blood Pressure; Celecoxib; Clinical Chemistry Tests; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Indomethacin; Kidney; Kidney Function Tests; Middle Aged; Pyrazoles; Sulfonamides | 2006 |
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Aspirin; Betamethasone; Birth Weight; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus, Patent; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Kidney; Metabolic Clearance Rate; Postmenopause; Pregnancy; Time Factors; Vancomycin | 2006 |
Mechanisms of adrenosensitivity in capsaicin induced hyperalgesia.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsaicin; Cholinergic Agents; Cross-Over Studies; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Hyperalgesia; Indomethacin; Iontophoresis; Male; Neurons, Afferent; Nociceptors; Norepinephrine; Pain; Prostaglandins; Sodium Chloride; Vasodilation | 2007 |
Indomethacin has a potent antiviral activity against SARS coronavirus.
Topics: Animals; Antiviral Agents; Aspirin; Cell Line; Chlorocebus aethiops; Coronavirus Infections; Coronavirus, Canine; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Feces; Humans; Indomethacin; Interferon-alpha; Ribavirin; RNA, Viral; Severe acute respiratory syndrome-related coronavirus; Virus Replication | 2006 |
Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.
Topics: Aspirin; Atorvastatin; Cell Separation; Coculture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Heptanoic Acids; HMGB1 Protein; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indomethacin; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyrroles; Recombinant Proteins; Simvastatin; STAT3 Transcription Factor; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Does rectal indomethacin given for prevention of post-ERCP pancreatitis increase bleeding after biliary endoscopic sphincterotomy or cardiovascular mortality?: Post hoc analysis using prospective clinical trial data.
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cholangiopancreatography, Endoscopic Retrograde; Clopidogrel; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Pancreatitis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Sphincterotomy, Endoscopic; Ticlopidine | 2014 |
1976 other study(ies) available for aspirin and indomethacin
| Article | Year |
|---|---|
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Lethal Dose 50; Mice; Pyridines; Rats; Structure-Activity Relationship | 1978 |
3-Phenyl-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]indole-2-carbonitrile, a potent inhibitor of prostaglandin synthetase and of platelet aggregation.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Diarrhea; Humans; In Vitro Techniques; Indomethacin; Lethal Dose 50; Mice; Nitriles; Platelet Aggregation; Prostaglandins F; Rats | 1979 |
Novel analgesic-antiinflammatory salicylates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship | 1978 |
Syntheses of N-substituted 2(3,4)-pyridylcarboxylic acid hydrazides with analgesic and antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Hydrazines; Male; Mice; Pyridines; Rats; Structure-Activity Relationship | 1979 |
Analgesic activity of novel spiro heterocycles. 2-Amino-7-oxa-3-thia-1-azaspiro[5,5]undec-1-enes and related compounds.
Topics: Analgesics; Animals; Female; Inflammation; Lethal Dose 50; Male; Mice; Quinones; Rats; Reaction Time; Spiro Compounds; Structure-Activity Relationship | 1978 |
Synthesis of 3-(2-pyridylethyl)benzoxazolinone derivatives: potent analgesic and antiinflammatory compounds inhibiting prostaglandin E2.
Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoxazoles; Dinoprostone; Edema; Female; Indomethacin; Mice; Molecular Structure; Pyridines; Stomach Ulcer; Structure-Activity Relationship | 1992 |
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats | 1989 |
9,11-Epoxy-9-homo-14-oxaprosta-5-enoic acid derivatives. Novel inhibitors of fatty acid cyclooxygenase.
Topics: Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Humans; Indomethacin; Molecular Conformation; Platelet Aggregation; Prostaglandins, Synthetic; Structure-Activity Relationship | 1986 |
Benzimidazole derivatives with atypical antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Benzimidazoles; Carrageenan; Cyclooxygenase Inhibitors; Edema; Exocytosis; Humans; Lysosomes; Male; Neutrophils; Rats; Rats, Inbred Lew; Structure-Activity Relationship | 1987 |
Synthetic aci-reductones: 3,4-dihydroxy-2H-1-benzopyran-2-ones and their cis- and trans-4a,5,6,7,8,8a-hexahydro diastereomers. Antiaggregatory, antilipidemic, and redox properties compared to those of the 4-substituted 2-hydroxytetronic acids.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Blood Platelets; Chemical Phenomena; Chemistry; Cholesterol; Coumarins; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Male; Oxidation-Reduction; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Structure-Activity Relationship; Triglycerides | 1988 |
Preparation and antiarthritic and analgesic activity of 4,5-diaryl-2-(substituted thio)-1H-imidazoles and their sulfoxides and sulfones.
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena; Chemistry; Female; Imidazoles; Indomethacin; Male; Mice; Phenylbutazone; Rats; Rats, Inbred Lew; Structure-Activity Relationship; Sulfones; Sulfoxides | 1985 |
Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena; Chemistry; Disease Models, Animal; Indicators and Reagents; Indomethacin; Phenylalanine; Pleurisy; Rats; Structure-Activity Relationship | 1984 |
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclinical; Edema; Granuloma; Imidazoles; Indicators and Reagents; Male; Naphthalenes; Pain; Rats; Stomach Ulcer; Structure-Activity Relationship | 1984 |
6-Aryl-4,5-dihydro-3(2H)-pyridazinones. A new class of compounds with platelet aggregation inhibiting and hypotensive activities.
Topics: Animals; Aspirin; Blood Pressure; Dihydralazine; Humans; Platelet Aggregation; Pyridazines; Rats | 1983 |
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles | 1981 |
Synthesis of N-(carbonylamino)-1,2,3,6-tetrahydropyridines with analgesic, antiinflammatory, and hyperglycemic activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Glucose; Chemical Phenomena; Chemistry; Female; Male; Mice; Pyridines; Rats; Rats, Inbred Strains | 1982 |
Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides. Potent nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Isoxazoles; Male; Oxazoles; Piroxicam; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines | 1982 |
Synthesis of N-[[(substituted-phenyl)carbonyl]amino]-1,2,3,6-tetrahydropyridines with analgesic and hyperglycemic activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Glucose; Chemical Phenomena; Chemistry; Female; Hypoglycemic Agents; Male; Mice; Pyridines; Rats; Rats, Inbred Strains; Solubility | 1982 |
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Pyrroles; Rats; Structure-Activity Relationship | 1995 |
N-substituted oxazolo[5,4-b]pyridin-2(1H)-ones: a new class of non-opiate antinociceptive agents.
Topics: Analgesics; Animals; Behavior, Animal; Male; Mice; Oxazoles; Pyridines; Rats; Rats, Wistar | 1995 |
Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; Drug Tolerance; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1994 |
Isolation of two new antiinflammatory biflavanoids from Sarcophyte piriei.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Exocytosis; Flavanones; Flavonoids; Glycosides; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Microsomes; Plants, Medicinal; Platelet Activating Factor; Prostaglandins; Somalia; Spectrometry, Mass, Fast Atom Bombardment | 1996 |
Novel antiplatelet constituents from formosan moraceous plants.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Flavonoids; Humans; In Vitro Techniques; Plants, Medicinal; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Taiwan | 1996 |
Antiplatelet arylnaphthalide lignans from Justicia procumbens.
Topics: Animals; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Naphthalenes; Nephelometry and Turbidimetry; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry, Infrared | 1996 |
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
Two new isoflavones from Ceiba pentandra and their effect on cyclooxygenase-catalyzed prostaglandin biosynthesis.
Topics: Animals; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Glucosides; Isoenzymes; Isoflavones; Magnetic Resonance Spectroscopy; Plant Epidermis; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1998 |
Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid.
Topics: Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line, Transformed; Cell Nucleus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Indicators and Reagents; Isoenzymes; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Malondialdehyde; Membrane Proteins; Models, Molecular; Molecular Conformation; Molecular Structure; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship | 1998 |
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Complementary; HeLa Cells; Humans; Kidney; Molecular Sequence Data; p-Aminohippuric Acid; Protein Kinase C; Rats; Substrate Specificity; Tissue Distribution | 1999 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo).
Topics: Allylbenzene Derivatives; Animals; Anisoles; Fibrinolytic Agents; Humans; Hypolipidemic Agents; In Vitro Techniques; Lung; Male; Mice; Platelet Aggregation; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Thromboembolism | 2000 |
Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents.
Topics: Alkanes; Arachidonic Acid; Collagen; Combinatorial Chemistry Techniques; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinolines; Structure-Activity Relationship; Thrombin | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid | 2002 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Lanostane triterpenoids and triterpene glycosides from the fruit body of Fomitopsis pinicola and their inhibitory activity against COX-1 and COX-2.
Topics: Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fruiting Bodies, Fungal; Japan; Lanosterol; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polyporaceae; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Triterpenes | 2005 |
Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azo Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Esters; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Prodrugs; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Rats; Stomach Ulcer; Structure-Activity Relationship | 2005 |
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Synthesis and pharmacological evaluation of 1H-imidazoles as ligands for the estrogen receptor and cytotoxic inhibitors of the cyclooxygenase.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Humans; Imidazoles; Models, Molecular; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.
Topics: Analgesics; Anilides; Animals; Benzenesulfonates; Carrageenan; Colorimetry; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Edema; Gastric Mucosa; Indicators and Reagents; Indomethacin; Kinetics; Male; Mice; Molecular Conformation; Rats; Sheep; Stomach Ulcer; Structure-Activity Relationship | 2007 |
Preparation of 5-aryl-3-alkylthio-l,2,4-triazoles and corresponding sulfones with antiinflammatory-analgesic activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Mice; Molecular Structure; Stomach Ulcer; Sulfones; Triazoles | 2007 |
The evaluation and structure-activity relationships of 2-benzoylaminobenzoic esters and their analogues as anti-inflammatory and anti-platelet aggregation agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Benzoates; Esters; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteinase Inhibitory Proteins, Secretory; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Superoxides | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Methylation; Molecular Structure; Nitric Oxide; Oleic Acid; Oxygen; Rats; Sheep; Stomach Ulcer; Structure-Activity Relationship | 2007 |
1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzoxazoles; Crystallography, X-Ray; Edema; Hindlimb; Hydrazones; Methylation; Mice; Microbial Viability; Models, Molecular; Molecular Structure; Semicarbazides; Structure-Activity Relationship; Thiadiazoles; Triazoles | 2007 |
A new therapeutic approach in Alzheimer disease: some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics.
Topics: Alzheimer Disease; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Hindlimb; Hydrogen Bonding; Isoenzymes; Mice; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity.
Topics: Acetates; Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Indenes; Inflammation; Proadifen; Rats; Ulcer | 2008 |
Aromatic amide derivatives of 5,6-dimethoxy-2,3-dihydro-1H-inden(-1-yl)acetic acid as anti-inflammatory agents free of ulcerogenic liability.
Topics: Acetates; Amides; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Edema; Enzyme Inhibitors; Indenes; Male; Mice; Molecular Structure; Rats; Ulcer | 2007 |
Synthesis, analgesic, anti-inflammatory, and antimicrobial activity of some novel pyrimido[4,5-b]quinolin-4-ones.
Topics: Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Quinolines | 2008 |
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software | 2008 |
Selenium containing heterocycles: synthesis, anti-inflammatory, analgesic and anti-microbial activities of some new 4-cyanopyridazine-3(2H)selenone derivatives.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Drug Design; Fungi; Heterocyclic Compounds; Inflammation; Lethal Dose 50; Mice; Organoselenium Compounds; Rats | 2008 |
Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azo Compounds; Carrageenan; Drug Design; Edema; Indomethacin; Molecular Structure; Nitric Oxide; Nitric Oxide Donors; Prodrugs; Pyrrolidines; Rats; Stomach Ulcer | 2008 |
Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor.
Topics: Aminopyridines; Animals; Benzamides; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Molecular Structure; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Stomach | 2008 |
Synthesis and anti-platelet evaluation of 2-benzoylaminobenzoate analogs.
Topics: Aminobenzoates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Structure-Activity Relationship | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Bacteria; Drug Evaluation, Preclinical; Fungi; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Piperidines; Spectrum Analysis; Structure-Activity Relationship | 2009 |
Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities.
Topics: Alternaria; Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacillus cereus; Fusarium; Indomethacin; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Salmonella typhi; Structure-Activity Relationship; Thiophenes | 2008 |
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Carrageenan; Drug Discovery; Edema; Female; Lipid Peroxidation; Male; Mice; Microwaves; Nucleosides; Quinolines; Rats | 2009 |
Inhibitory effect of macabarterin, a polyoxygenated ellagitannin from Macaranga barteri, on human neutrophil respiratory burst activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cameroon; Ellagic Acid; Euphorbiaceae; Glycosides; Humans; Hydrolyzable Tannins; Molecular Structure; Neutrophils; Plant Bark; Respiratory Burst | 2008 |
Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Drug Design; Humans; Ibuprofen; Indomethacin; Nitric Oxide; Nitric Oxide Donors; Prodrugs; Rats; Sheep | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Synthesis and analgesic and anti-inflammatory activities 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(p-substituted/nonsubstituted benzal)hydrazone derivatives.
Topics: Abdominal Pain; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Hydrazones; Inflammation; Male; Mice; Pain Measurement; Pyridazines; Structure-Activity Relationship | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Female; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Pain Measurement; Thiadiazines; Triazoles; Ulcer | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Synthesis, biological and medicinal significance of S-glycosido-thieno[2,3-d]-pyrimidines as new anti-inflammatory and analgesic agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Magnetic Resonance Spectroscopy; Male; Mice; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2010 |
Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Carrageenan; Edema; Male; Mice; Rats; Ulcer | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
3-Formylchromones: potential antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromones; Cyclooxygenase Inhibitors; Edema; Female; Inflammation; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Respiratory Burst; Xanthine; Xanthine Oxidase | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Humans; Ibuprofen; Indomethacin; Nitric Oxide; Nitric Oxide Donors; Peptic Ulcer; Phenylethyl Alcohol; Prodrugs; Rats; Recombinant Proteins; Structure-Activity Relationship | 2012 |
Synthesis of new 5,6-dihydrobenzo[h]quinazoline 2,4-diamino substituted and antiplatelet/antiphlogistic activities evaluation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Dose-Response Relationship, Drug; Drug Design; Edema; Guinea Pigs; Mice; Models, Molecular; Molecular Structure; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Quinazolines; Rats; Stereoisomerism; Structure-Activity Relationship | 2012 |
N-1 and C-3 substituted indole Schiff bases as selective COX-2 inhibitors: synthesis and biological evaluation.
Topics: Animals; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Humans; Indoles; Indomethacin; Kinetics; Models, Molecular; Recombinant Proteins; Schiff Bases; Sheep; Solutions; Structure-Activity Relationship | 2012 |
Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Biological Assay; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclization; Disease Models, Animal; Drug Design; Female; Humans; Inhibitory Concentration 50; Mice; Pyrimidines; Thiourea | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation.
Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Structure-Activity Relationship | 2013 |
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors.
Topics: Animals; Blood Platelets; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Female; Fibrinolytic Agents; Furans; Humans; Isoxazoles; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Structure-Activity Relationship; Thromboxane A2 | 2013 |
High analgesic and anti-inflammatory in vivo activities of six new hybrids NSAIAs tetrahydropyran derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Mice; Molecular Structure; Motor Activity; Pyrans | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chromones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Indoles; Mice; Models, Molecular; Molecular Structure; Pain; Pain Measurement; Pyrazoles; Structure-Activity Relationship | 2014 |
Indomethacin Analogues that Enhance Doxorubicin Cytotoxicity in Multidrug Resistant Cells without Cox Inhibitory Activity.
Topics: | 2011 |
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-
Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Dose-Response Relationship, Drug; Edema; Guinea Pigs; Locomotion; Mice; Naphthyridines; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles | 2014 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents.
Topics: | 2015 |
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship | 2017 |
Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.
Topics: Benzylidene Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Hydrazines; Molecular Docking Simulation; Molecular Structure; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Structure-Activity Relationship | 2017 |
Anti-inflammatory 12,20-Epoxypregnane and 11,12-seco-Pregnane Glycosides from the Stems of Hoya kerrii.
Topics: Animals; Anti-Inflammatory Agents; Apocynaceae; Crystallography, X-Ray; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glycosides; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Mice; Molecular Conformation; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Nuclear Magnetic Resonance, Biomolecular; Plant Stems; Pregnanes; Thailand | 2017 |
Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biosynthetic Pathways; Cells, Cultured; Dinoprostone; Mice, Inbred C57BL; Pyrimidines; Structure-Activity Relationship | 2018 |
Novel Pyrazolo[4,3- d]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Crystallography, X-Ray; Dimerization; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Molecular Conformation; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Pyridines; Rats; RAW 264.7 Cells; Structure-Activity Relationship | 2019 |
Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Carrageenan; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Design; Edema; Enzyme Inhibitors; Female; Humans; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Pyrrolidines; Structure-Activity Relationship | 2020 |
A practical synthesis of amino limonin/deoxylimonin derivatives as effective mitigators against inflammation and nociception.
Topics: | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.
Topics: Animals; Aspirin; Epididymis; Indomethacin; Male; Mice; Organ Size; Prostaglandins E; Seminal Vesicles; Sertoli Cells; Spermatocytes; Spermatogenesis; Spermatogonia; Testis | 1975 |
Letter: Synthesis of prostaglandins durin anaphlaxis in guinea pig lung.
Topics: Anaphylaxis; Animals; Aspirin; Cyclic AMP; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indomethacin; Lung; Prostaglandins | 1976 |
Benorylate interaction with indomethacin and phenylbutazone.
Topics: Animals; Arthritis; Aspirin; Drug Interactions; Drug Synergism; Fever; Indomethacin; Male; Phenylbutazone; Rats; Salicylates; Time Factors | 1976 |
[Prevention of premature labor].
Topics: Adrenergic beta-Agonists; Aspirin; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Rheumatic Diseases; Verapamil | 1975 |
Possible involvement of prostaglandins in the contractile action of bradykinin on rat terminal ileum.
Topics: Animals; Aspirin; Bradykinin; Ileum; Indomethacin; Male; Muscle Contraction; Prostaglandins; Rats | 1976 |
Mediation of prostaglandin E2 in the biphasic response to ATP of the isolated tracheal muscle of guinea-pigs.
Topics: Adenosine Triphosphate; Animals; Aspirin; Drug Interactions; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Polyphloretin Phosphate; Prostaglandins E; Trachea | 1976 |
A comparison of the effect of flurbiprofen on prostaglandin synthetase from human rheumatoid synovium and enzymatically active animal tissues.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Indomethacin; Kidney Medulla; Male; Mixed Function Oxygenases; Propionates; Rabbits; Seminal Vesicles; Synovial Membrane | 1976 |
Antagonism of arachidonic acid hydroperoxide on isolated gastrointestinal tissues as a measure of the inhibition of prostaglandin biosynthesis.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Biological Assay; Bradykinin; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Peroxides; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Serotonin Antagonists; Thiophenes | 1976 |
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema; Female; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Niflumic Acid; Peptic Ulcer; Prostaglandins E; Pyrroles; Rats | 1976 |
Inhibition of prostaglandin biosynthesis by non-narcotic analgesic drugs.
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Depression, Chemical; Glafenine; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mice; ortho-Aminobenzoates; Prostaglandins; Quinolines; Rabbits; Rats | 1976 |
Platelet aggregation in the cerebral microcirculation: effect of aspirin and other agents.
Topics: Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Capillaries; Cerebral Arteries; Cerebrovascular Circulation; Disseminated Intravascular Coagulation; Heparin; Hydrogen-Ion Concentration; Indomethacin; Male; Mice; Mice, Inbred ICR; Microcirculation; Platelet Aggregation; Vascular Resistance | 1977 |
Ditazole and platelets. I. Effect of ditazole on human platelet function in vitro.
Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Tests; Carbon Radioisotopes; Humans; Indomethacin; Oxazoles; Platelet Aggregation; Serotonin; Thrombelastography | 1977 |
Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers.
Topics: Administration, Oral; Animals; Aspirin; Carbachol; Depression, Chemical; Disease Models, Animal; Duodenal Ulcer; Gastric Juice; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; Imidazoles; Indomethacin; Infusions, Parenteral; Ligation; Male; Pylorus; Rats; Reserpine; Serotonin; Stomach Ulcer; Stress, Physiological | 1977 |
Analgesic drugs in the management of pain.
Topics: Analgesics; Anti-Anxiety Agents; Aspirin; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Methadone; Morphine; Oxycodone; Pain; Pain, Intractable; Pentazocine; Pyrazoles | 1977 |
Influence of MAO-inhibitors, neuroleptics, morphine, mescaline, divascan, aconitine, and pyrogenes on prostaglandin-biosynthesis.
Topics: Aconitine; Aconitum; Adrenochrome; Animals; Antipsychotic Agents; Aspirin; Chlorpromazine; Colchicine; Epinephrine; Female; Haloperidol; Harmaline; In Vitro Techniques; Indolequinones; Indomethacin; Kidney Medulla; Male; Mescaline; Monoamine Oxidase Inhibitors; Morphine; Phenelzine; Phenylhydrazines; Prostaglandins; Pyrogens; Rabbits; Reserpine; Semicarbazones | 1977 |
Effects of aspirin-like drugs on canine gastric mucosal blood flow and acid secretion.
Topics: Acetaminophen; Animals; Aspirin; Dogs; Female; Gastric Mucosa; Indomethacin; Muscle Contraction; Muscle, Smooth; Pentagastrin; Prostaglandins E; Prostaglandins F; Regional Blood Flow; Salicylates | 1977 |
Prostaglandin synthetase systems in rat and rabbit renal medulla and inhibition by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kidney; Kidney Medulla; Male; Microsomes; Phenylbutazone; Prostaglandins E; Prostaglandins F; Rabbits; Rats | 1977 |
Inhibitors of gastric lesions in the rat.
Topics: Animals; Aspirin; Disease Models, Animal; Female; Glutamine; Histamine Antagonists; Indomethacin; Ligation; Pylorus; Rats; Salicylates; Stomach Ulcer; Stress, Physiological | 1978 |
Potential endogenous inhibitor of prostaglandin synthetase in plasma: failure to inhibit cyclo-oxygenase in platelets and the gastric mucosa.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dexamethasone; Gastric Mucosa; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation; Rats | 1978 |
Inhibition of leucocyte migration by salicylates and indomethacin.
Topics: Animals; Aspirin; Cell Movement; In Vitro Techniques; Indomethacin; Leukocytes; Male; Pleura; Rats; Salicylates; Time Factors | 1978 |
Arachidonic acid activation of guinea pig lung guanylate cyclase by two independent mechanisms.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dithiothreitol; Enzyme Activation; Fatty Acids, Unsaturated; Guanylate Cyclase; Guinea Pigs; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Lung; Male; Meclofenamic Acid; Microsomes; Phospholipases A; Phospholipases A2 | 1979 |
Raised plasma kininogen levels in rheumatoid patients-response to therapy with monsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Alpha-Globulins; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Female; Humans; Indomethacin; Kininogens; Male; Middle Aged; Pain; Serum Albumin; Time Factors | 1976 |
Absence of a prostaglandinic mediator in the lateral hypothalamic cardio-vascular inhibition.
Topics: Animals; Aspirin; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Electric Stimulation; Hypothalamus; Indomethacin; Paraventricular Hypothalamic Nucleus; Prostaglandins; Prostaglandins E | 1976 |
Schizophrenia as a prostaglandin deficiency disease.
Topics: Aspirin; Depression, Chemical; Humans; Indomethacin; Prostaglandins; Schizophrenia | 1977 |
Aspirin and renal function.
Topics: Adolescent; Adult; Aspirin; Female; Humans; Indomethacin; Kidney; Kidney Function Tests; Male; Middle Aged | 1977 |
Reflex neurovascular dystrophy in childhood.
Topics: Adolescent; Age Factors; Arm; Aspirin; Child; Exercise Therapy; Female; Humans; Indomethacin; Leg; Male; Reflex Sympathetic Dystrophy | 1978 |
Inhibition of ultraviolet and phototoxic dermatitis in the mouse.
Topics: Animals; Aspirin; Betamethasone; Chlorpromazine; Dermatitis; Female; Indomethacin; Mice; Photosensitivity Disorders; Spectrophotometry; Ultraviolet Rays | 1978 |
Anti-inflammatory drugs and tumour growth.
Topics: Animals; Aspirin; Bone Neoplasms; Carcinogens; Drug Evaluation; Humans; Indomethacin; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Prostaglandin Antagonists; Prostaglandins E; Rats | 1979 |
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin.
Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone | 1979 |
Solubilization and partial purification of prostaglandin endoperoxide synthetase of rabbit kidney medulla.
Topics: Animals; Arachidonic Acids; Aspirin; Hemoglobins; Indomethacin; Isomerases; Kidney; Kidney Medulla; Microsomes; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins H; Rabbits; Serotonin; Solubility; Sulfhydryl Reagents; Tryptophan | 1978 |
Flurbiprofen: highly potent inhibitor of prostaglandin synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Ibuprofen; Indomethacin; Male; Microsomes; Oxygen Consumption; Phenylbutazone; Propionates; Prostaglandins E; Seminal Vesicles | 1978 |
The inhibition of cyclo-oxygenase of rabbit platelets by aspirin is prevented by salicylic acid and by phenanthrolines.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dithiothreitol; In Vitro Techniques; Indomethacin; Phenanthrolines; Platelet Aggregation; Rabbits; Salicylates; Thromboxane A2; Time Factors | 1978 |
Changes in intracellular prostaglandin content during activation of lymphocytes by phytohaemagglutinin.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Indomethacin; Lymphocyte Activation; Lymphocytes; Phenylbutazone; Phytohemagglutinins; Prostaglandins; Prostaglandins E; Prostaglandins F; Swine | 1978 |
Prostaglandin biosynthesis in rabbit kidney medulla: inhibition in-vitro vs. in-vivo by aspirin, indomethacin and meclofenamic acid.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Indomethacin; Kidney Medulla; Meclofenamic Acid; ortho-Aminobenzoates; Prostaglandins; Rabbits; Time Factors | 1978 |
In vitro effect of the coronary vasodilator diltiazem on human and rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Benzazepines; Blood Platelets; Calcium; Collagen; Diltiazem; Egtazic Acid; Humans; Indomethacin; Male; Platelet Aggregation; Rabbits; Vasodilator Agents | 1978 |
Isolation of a new lipoxygenase metabolite of arachidonic acid, 8. 11, 12-trihydroxy-5,9,14-eicosatrienoic acid from human platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Chemical Phenomena; Chemistry; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase | 1979 |
Effects of prostaglandins and some anti-inflammatory drugs on the binding of 7,12-dimethylbenz[alpha]anthracene to the DNA of murine epidermal cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Aspirin; Benz(a)Anthracenes; Cells, Cultured; DNA; Flufenamic Acid; Fluocinolone Acetonide; Indomethacin; Mice; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Skin | 1979 |
Prostaglandin synthetase inhibitors antagonize the depressant effects of ethanol.
Topics: Acetaminophen; Animals; Aspirin; Behavior, Animal; Butanols; Chloral Hydrate; Cyclooxygenase Inhibitors; Ethanol; Flufenamic Acid; Indomethacin; Male; Mefenamic Acid; Mice; Pentobarbital; Sleep | 1979 |
Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Lipoxygenase Inhibitors; Peroxidases; Salicylates; Thrombin | 1979 |
Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Indomethacin; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 1979 |
A comparison of the abilities of acetylsalicylic acid, flurbiprofen and indomethacin to inhibit the release reaction and prostaglandin synthesis in human blood platelets.
Topics: Aspirin; Blood Platelets; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Propionates; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Time Factors | 1979 |
Potentiation by indomethacin of TRH-induced TSH secretion in the rat.
Topics: Animals; Aspirin; Drug Synergism; Indomethacin; Male; Rats; Thyroidectomy; Thyrotropin; Thyrotropin-Releasing Hormone | 1979 |
Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Female; Humans; Indomethacin; Injections, Intravenous; Male; Middle Aged | 1979 |
Effect of Sar1-ala8-angiotensin II on blood pressure and renin in Bartter's syndrome, before and after treatment with prostaglandin synthetase inhibitors.
Topics: Adolescent; Adult; Angiotensin II; Aspirin; Bartter Syndrome; Blood Pressure; Cyclooxygenase Inhibitors; Electrolytes; Female; Humans; Hyperaldosteronism; Indomethacin; Male; Prostaglandins; Renin; Saralasin | 1979 |
Contribution of prostaglandins to the regulation of pulmonary vascular resistance in adult cats and dogs.
Topics: Animals; Arachidonic Acids; Aspirin; Cats; Cyclooxygenase Inhibitors; Dogs; Hypoxia; Indomethacin; Meclofenamic Acid; Prostaglandins F; Pulmonary Veins; Vascular Resistance | 1979 |
Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy.
Topics: Angiotensin II; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Infusions, Parenteral; Pregnancy; Pregnancy Complications, Cardiovascular | 1978 |
Collagen synthesis and prostaglandin inhibition in burns.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Collagen; Dinoprostone; Indomethacin; Rats; Rats, Inbred Strains | 1978 |
Single and multiple drug therapy in autologous immune complex nephritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Basement Membrane; Complement C3; Cyclophosphamide; Cyproheptadine; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Immune Complex Diseases; Immunoglobulin G; Immunosuppressive Agents; Indomethacin; Kidney Glomerulus; Male; Methylprednisolone; Proteinuria; Rats | 1976 |
Mechanical and chemical properties of various connective tissue organs in rats as influenced by non-steroidal antirheumatic drugs.
Topics: Animals; Aspirin; Biomechanical Phenomena; Bone and Bones; Cartilage; Collagen; Connective Tissue; Granuloma; Indomethacin; Phenylbutazone; Rats; Skin; Tendons; Tensile Strength | 1977 |
[Kinetics of I-131 fibrinogen in cancer patients: pharmacological approach].
Topics: Aspirin; Blood Coagulation; Fibrinogen; Fibrinolytic Agents; Heparin; Indomethacin; Iodine Radioisotopes; Kinetics; Neoplasms; Platelet Aggregation; Prednisone; Pyridines; Thiophenes | 1977 |
Effect of indomethacin on Ca2+-stimulated adenosine triphosphatase in the microsomes of rat submandibular gland.
Topics: Animals; Aspirin; Calcium; Calcium-Transporting ATPases; Indomethacin; Microsomes; Rats; Submandibular Gland | 1979 |
On the enzymatic response to injury and its mediators.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Burns; Indomethacin; Inflammation; Male; Mefenamic Acid; Prostaglandin-Endoperoxide Synthases; Rats; Skin; Wounds and Injuries | 1979 |
Agents affecting osteolysis in patients with breast cancer.
Topics: Anti-Inflammatory Agents; Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Female; Flurbiprofen; Humans; Indomethacin; Osteolysis; Plicamycin; Time Factors | 1979 |
Regulation of thyroid ornithine ornithine decarboxylase (ODC) by thyrotropin. I. The rat.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Carboxy-Lyases; Colchicine; Cyclic AMP; Indomethacin; Kinetics; Male; Naproxen; Organ Size; Ornithine Decarboxylase; Phenylbutazone; Prostaglandins E; Putrescine; Rats; Thyroid Gland; Thyrotropin; Time Factors; Triiodothyronine; Vinblastine | 1975 |
Action of luteinizing hormone-releasing hormone and synthesis of prostaglandin in the pituitary gland.
Topics: Animals; Aspirin; Cyclic AMP; Depression, Chemical; Flufenamic Acid; Gonadotropin-Releasing Hormone; Indomethacin; Luteinizing Hormone; Male; Pituitary Gland; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Stimulation, Chemical | 1975 |
Blocking of dog thyroid secretion in vitro by inhibitors of prostaglandin synthesis.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Aspirin; Cyclic AMP; Dogs; In Vitro Techniques; Indomethacin; Iodides; Iodine Radioisotopes; Kinetics; Lactates; Prostaglandin Antagonists; Prostaglandins; Secretory Rate; Thyroid Gland; Thyrotropin | 1975 |
Regulation of adrenergic neuromuscular transmission in the rabbit iris.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Calcium; Cocaine; Electric Stimulation; In Vitro Techniques; Indomethacin; Iris; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Tyramine | 1975 |
Prostaglandins in the rheumatic diseases.
Topics: Arthritis, Rheumatoid; Aspirin; Bone Resorption; Cell Line; Colchicine; Cyclic AMP; Flufenamic Acid; Indomethacin; Organ Culture Techniques; Osteoarthritis; Prostaglandins; Prostaglandins E; Prostaglandins F; Synovial Fluid; Synovial Membrane | 1975 |
The effect of inhibition of prostaglandin synthesis on ovarian hypertrophy in the rat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Aspirin; Body Weight; Castration; Female; Gonadotropins, Equine; Indomethacin; Organ Size; Ovary; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats | 1975 |
[Effect of non-steroid antirheumatic drugs on the activity of collagenase].
Topics: Anti-Inflammatory Agents; Aspirin; Chloroquine; Flufenamic Acid; Humans; In Vitro Techniques; Indomethacin; Microbial Collagenase; Phenylbutazone | 1975 |
Intrinsic mineralocorticoid agonist activity of some nonsteroidal anti-inflammatory drugs. A postulated mechanism for sodium retention.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Binding Sites; Binding, Competitive; Cytosol; Indomethacin; Kidney; Male; Mineralocorticoids; Oxyphenbutazone; Phenylbutazone; Rats; Receptors, Cell Surface; Sodium; Sodium Salicylate | 1976 |
The effect of non-steroid anti-inflammatory drugs, dibutyryl cyclic 3',5'-adenosine monophosphate and phosphodiesterase inhibitors on platelet aggregation and the platelet release reaction in normal and essential fatty acid deficient rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bucladesine; Caffeine; Depression, Chemical; Dipyridamole; Fatty Acids, Essential; Indomethacin; Papaverine; Phosphodiesterase Inhibitors; Platelet Aggregation; Rats | 1975 |
[Prostaglandins and reproduction].
Topics: Animals; Aspirin; Corpus Luteum; Cricetinae; Cyclic AMP; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Indomethacin; Luteinizing Hormone; Male; Mice; Ovary; Ovulation; Pregnancy; Progesterone; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Rats; Reproduction; Sheep; Spermatogenesis; Spermatozoa | 1975 |
[Multiple manifestations of intolerance of a combination of anti-inflammatory drugs. Role of phenylbutazone].
Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Duodenal Ulcer; Erythema; Female; Humans; Indomethacin; Jaundice; Middle Aged; Phenylbutazone; Purpura, Thrombocytopenic | 1975 |
Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins.
Topics: Acetylation; Aspirin; Ditiocarb; Enzyme Activation; Indomethacin; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1976 |
Roles of cyclic nucleotides in platelet function.
Topics: Acetylcholine; Adenosine Diphosphate; Adenylyl Cyclases; Arginine Vasopressin; Aspirin; Blood Platelets; Calcium; Carbachol; Collagen; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Papaverine; Platelet Aggregation; Prostaglandins E | 1975 |
Prostaglandin mediation of collagenase-induced bone resorption.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Culture Techniques; Indomethacin; Mice; Microbial Collagenase; Prostaglandins | 1976 |
Prostaglandin release from human polymorphonuclear leukocytes.
Topics: Aspirin; Bucladesine; Humans; Indomethacin; Inflammation; Neutrophils; Phagocytosis; Prostaglandins; Prostaglandins E; Prostaglandins F; Zymosan | 1976 |
Stimulation by TSH of prostaglandin synthesis in pig thyroid.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Cyclic AMP; Enzyme Activation; Indomethacin; Lipase; Phosphatidylcholines; Phosphatidylinositols; Phospholipases; Phospholipids; Prostaglandins; Swine; Thyroid Gland; Thyrotropin; Triglycerides | 1976 |
Differential effects of prostaglandin synthetase inhibitors on prostaglandin E2 binding and on prostaglandin- or cholera toxin-induced cyclic AMP accumulation in the rabbit uterus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aspirin; Bacterial Toxins; Cyclic AMP; Female; Flufenamic Acid; Indomethacin; Phosphoric Diester Hydrolases; Prostaglandins E; Rabbits; Receptors, Prostaglandin; Uterus; Vibrio cholerae; Xanthines | 1976 |
Effects of prostaglandin synthetase inhibitors and prostaglandin precursors on anterior pituitary cyclic AMP and hormone secretion.
Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acids; Aspirin; Cyclic AMP; Fatty Acids, Unsaturated; Gonadotropin-Releasing Hormone; Growth Hormone; Indomethacin; Luteinizing Hormone; Pituitary Gland; Pituitary Gland, Anterior; Thyrotropin | 1976 |
[Effect of antikinin agents on the course of experimental myocarditis].
Topics: Aminocaproates; Animals; Aprotinin; Aspirin; Drug Evaluation; Drug Therapy, Combination; Indomethacin; Kallikreins; Kinins; Lysine Carboxypeptidase; Myocarditis; Peptidyl-Dipeptidase A; Pyridinolcarbamate; Rabbits | 1976 |
Possible relation of prostaglandins to PMN-derived mediators of host metabolic responses to inflammation.
Topics: Amino Acids; Animals; Aspirin; Biological Assay; Bucladesine; Cells, Cultured; Cyclic GMP; Cyclooxygenase Inhibitors; Indomethacin; Inflammation; Leukocyte Count; Mixed Function Oxygenases; Morphine; Neutrophils; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Zinc | 1977 |
Characterization of the group of patients with the hypercalcemia of cancer who respond to treatment with prostaglandin synthesis inhibitors.
Topics: Aspirin; Calcium; Cyclic AMP; Humans; Hypercalcemia; Hyperparathyroidism; Indomethacin; Neoplasm Metastasis; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Prostaglandin Antagonists; Prostaglandins E | 1976 |
Prostaglandins in adrenergic transmission of isolated perfused rat pancreas.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Arteries; Aspirin; Electric Stimulation; Indomethacin; Male; Meclofenamic Acid; Norepinephrine; Pancreas; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Sympathetic Nervous System; Synaptic Transmission; Vasomotor System | 1977 |
The involvement of prostaglandin endoperoxide formation in the elevation of cyclic GMP levels during platelet aggregation.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Humans; Indomethacin; Peroxides; Platelet Aggregation; Prostaglandins | 1977 |
Inhibition of acyl coenzyme A:lysolecithin acyltransferases by local anesthetics, detergents and inhibitors of cyclic nucleotide phosphodiesterases.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyltransferases; Anesthetics, Local; Animals; Aspirin; Cell Line; Detergents; Gastric Mucosa; Indomethacin; Liver; Mice; Myocardium; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rabbits; Rats | 1977 |
Prostaglandin E2 production in 3T3 cells transformed by polyoma virus raises the intracellular adenosine 3':5'-monophosphate levels.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Indomethacin; Kinetics; Polyomavirus; Prostaglandins E | 1977 |
In vitro osteolysis by human breast tumours.
Topics: Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Female; Humans; In Vitro Techniques; Indomethacin; Microbial Collagenase; Neoplasm Metastasis; Osteolysis; Prostaglandins | 1977 |
[Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits].
Topics: Aminocaproic Acid; Animals; Aprotinin; Aspirin; Heart; Hypersensitivity; Indomethacin; Kininogens; Kinins; Lysine Carboxypeptidase; Myocarditis; Myocardium; Peptidyl-Dipeptidase A; Pyridinolcarbamate; Rabbits | 1976 |
Prostaglandin synthesis inhibition and the action of vasopressin: studies in man and rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Animals; Aspirin; Diuresis; Glomerular Filtration Rate; Humans; Indomethacin; Kidney; Male; Natriuresis; Potassium; Prostaglandins; Rats; Vasopressins | 1977 |
Effect of prostaglandin synthetase inhibitors of basal and ACTH-stimulated steroid synthesis by separated adrenocortical zones.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Aspirin; Corticosterone; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rats | 1977 |
Inhibition of prostaglandin synthesis in mouse 3T3 fibroblasts and human platelets by substituted phenols.
Topics: Animals; Aspirin; Blood Platelets; Cresols; Cyclic AMP; Fibroblasts; Humans; Indomethacin; Mice; Phenols; Platelet Aggregation; Prostaglandins; Serotonin | 1977 |
Studies on the mechanism of flush induced by nicotinic acid.
Topics: Animals; Aspirin; Cyclic AMP; Cyclooxygenase Inhibitors; Drug Interactions; Ear, External; Female; Guinea Pigs; Hyperemia; Indomethacin; Male; Nicotinic Acids; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Skin Temperature | 1977 |
The predominant contribution of platelets to baseline and ascorbate-stimulated increments in cyclic GMP in human mononuclear leukocyte preparations.
Topics: Ascorbic Acid; Aspirin; Blood Platelets; Carrier Proteins; Cyclic GMP; Humans; Indomethacin; Monocytes; Radioimmunoassay | 1978 |
Effect of acetaminophen on prostaglandin E2 and prostaglandin F2alpha synthesis in the renal inner medulla of rat.
Topics: Acetaminophen; Animals; Arachidonic Acids; Aspirin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Kidney Medulla; Prostaglandins E; Prostaglandins F; Rats | 1978 |
Effects of epinephrine, indomethacin, acetylsalicyclic acid, dexamethasone, and cyclic AMP on the in vitro activity of lysosomal hyaluronidase from the rabbit iris.
Topics: Acid Phosphatase; Animals; Aspirin; Cattle; Cyclic AMP; Dexamethasone; Epinephrine; Hyaluronoglucosaminidase; In Vitro Techniques; Indomethacin; Iris; Lysosomes; Male; Rabbits; Testis | 1978 |
Effects of adenosine triphosphate and prostaglandins on vascular adrenergic transmission.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Aspirin; Blood Vessels; Female; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction | 1978 |
Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs.
Topics: 6-Aminonicotinamide; Anti-Inflammatory Agents; Antimetabolites; Aspirin; Aurothioglucose; Chemotaxis, Leukocyte; Deoxyglucose; Dose-Response Relationship, Drug; Ethylmaleimide; Free Radicals; Glycolysis; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Iodoacetates; Neutrophils; Ouabain; Oxygen; Phenylbutazone; Superoxides | 1979 |
Collagenase production by synovial fibroblasts treated with phorbol myristate acetate.
Topics: Animals; Aspirin; Carbon Radioisotopes; Cell Count; Cells, Cultured; Cyclic AMP; DNA; Fibroblasts; Indomethacin; L-Lactate Dehydrogenase; Leucine; Microbial Collagenase; Models, Biological; Phorbols; Prostaglandins E; Protein Binding; Protein Biosynthesis; Rabbits; Radioimmunoassay; Synovial Membrane; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tritium | 1979 |
Effect of two prostaglandin synthesis inhibitors, indomethacin and acetylsalicylic acid, on plasma ACTH and cortisol levels in man.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Aspirin; Blood Glucose; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Indomethacin; Insulin; Middle Aged; Pituitary-Adrenal System; Prostaglandins | 1979 |
Evaluation of antiinflammatory and antithrombotic drugs in pulmonary and arterial thrombosis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anti-Inflammatory Agents; Arterial Occlusive Diseases; Aspirin; Benzophenones; Carotid Arteries; Cattle; Dipyridamole; Drug Evaluation; Fibrinolytic Agents; Humans; Imidazoles; Indoles; Indomethacin; Lung Diseases, Obstructive; Male; Mice; Platelet Aggregation; Prostaglandins; Pyridines; Quinazolines; Rats; Sulfinpyrazone; Sulfonamides; Suloctidil; Thiophenes | 1979 |
Inhibitors of prostaglandin synthesis as inhibitors of herpes simplex virus replication.
Topics: Animals; Aspirin; DNA Replication; DNA, Viral; Flufenamic Acid; Indomethacin; Mefenamic Acid; Mice; Prostaglandin Antagonists; Prostaglandins; Simplexvirus; Virus Replication | 1979 |
Divergent effects of prostaglandin synthesis inhibitors on pulmonary cyclic 3', 5'-adenosine monophosphate and cyclic 3', 5'-guanosine monophosphate levels in untreated and histamine sensitized mice.
Topics: Animals; Aspirin; Cyclic AMP; Cyclic GMP; Female; Histamine; Indomethacin; Lung; Mice; Mice, Inbred ICR; Pertussis Vaccine; Prostaglandins | 1979 |
Prostaglandin-like activity in the aqueous humor following alkali burns.
Topics: Alkalies; Animals; Aqueous Humor; Aspirin; Blood Pressure; Burns, Chemical; Hydrogen-Ion Concentration; Hydrolysis; Indomethacin; Intraocular Pressure; Prostaglandins; Rabbits; Sodium Hydroxide; Time Factors | 1975 |
The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Drug Therapy, Combination; Female; Humans; Indomethacin; Isoproterenol; Muscle Contraction; Obstetric Labor, Premature; Oxytocin; Papaverine; Parasympatholytics; Pregnancy; Prostaglandin Antagonists; Rats; Uterus; Verapamil | 1975 |
A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Drug Therapy, Combination; Female; Gold Sodium Thiomalate; Haptoglobins; Humans; Indomethacin; Male; Middle Aged; Penicillamine; Phenylacetates; Tryptophan | 1975 |
Prostaglandin synthetase activity from human rheumatoid synovial tissue and its inhibition by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cattle; Depression, Chemical; Flurbiprofen; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Kidney Medulla; Male; Microsomes; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Rabbits; Seminal Vesicles; Synovial Membrane | 1975 |
Effects of brain trauma on undamaged cerebral microvessels.
Topics: Animals; Aspirin; Brain; Brain Injuries; Indomethacin; Mice; Microcirculation; Platelet Aggregation | 1977 |
Actions of anti-inflammatory drugs on smooth muscle.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Humans; In Vitro Techniques; Indomethacin; Muscle, Smooth; Myocardial Contraction; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins | 1977 |
Interactions of anti-rheumatic drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Furosemide; Humans; Indomethacin; Phenobarbital | 1977 |
A pharmacokinetic approach to the understanding of therapeutic effects and side effects of salicylates.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Gastric Mucosa; Humans; Indomethacin; Kidney; Phenylbutazone; Salicylates; Stomach; Tissue Distribution | 1977 |
Effects of anti-inflammatory drugs on the carrageenin-induced hind paw inflammation of rats deprived of endogenous precursors of prostaglandins.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Dexamethasone; Fatty Acids, Essential; Indomethacin; Inflammation; Male; Organ Size; Prostaglandins; Rats | 1977 |
Prevention of postoperative ocular hypertension by prostaglandin inhibitors.
Topics: Aspirin; Cataract Extraction; Depression, Chemical; Humans; Indomethacin; Intraocular Pressure; Postoperative Complications; Prostaglandin Antagonists | 1977 |
Prostaglandins and the development of gastric mucosal damage by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Gastric Mucosa; Humans; Indomethacin; Mucus; Prostaglandins; Prostaglandins E; Rats | 1979 |
Peroxidase reactions during prostaglandin biosynthesis and their relationship to inflammation.
Topics: Animals; Arachidonic Acids; Aspirin; Indomethacin; Inflammation; Male; Mass Spectrometry; Peroxidases; Prostaglandins; Seminal Vesicles; Sheep | 1979 |
Action of nonsteroidal, anti-inflammatory drugs on human and rat peripheral leucocyte migration in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Migration Inhibition; Cell Movement; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Leukocytes; Phenylbutazone; Rats; Sodium Salicylate | 1977 |
Gastric mucosal injury from common drugs.
Topics: Adrenal Cortex Hormones; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Indomethacin; Phenylbutazone; Stomach Diseases; Stomach Ulcer | 1978 |
[Immunological aspects of rheumatoid arthritis].
Topics: Adolescent; Antibodies, Antinuclear; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; B-Lymphocytes; Child; Child, Preschool; Female; Hemagglutination Tests; Humans; Immunoglobulins; Indomethacin; Latex Fixation Tests; Lymphocytes; Male; Methylprednisolone; Rheumatoid Factor; Rosette Formation; T-Lymphocytes | 1978 |
Prostaglandin synthesis inhibited by formamidine pesticides.
Topics: Amidines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Chlorphenamidine; In Vitro Techniques; Indomethacin; Insecticides; Male; Microsomes; Prostaglandins; Prostaglandins E; Rats; Seminal Vesicles; Toluidines | 1978 |
Salicylate-induced enzymuria: comparison with other anti-inflammatory agents.
Topics: Acetaminophen; Acetylglucosaminidase; Adult; Anti-Inflammatory Agents; Aspirin; Gold; Hexosaminidases; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Diseases; Lysosomes; Rheumatic Diseases; Salicylates | 1978 |
Antirheumatic agents.
Topics: Adrenal Cortex Hormones; Antimalarials; Aspirin; Azathioprine; Chloroquine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Indomethacin; Penicillamine; Phenylbutazone; Phenylpropionates; Rheumatic Diseases; Salicylates; Sulindac; Tolmetin | 1979 |
Non-steroidal anti-inflammatory drugs: use in rheumatic diseases.
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Indomethacin; Phenylbutazone; Rheumatic Diseases | 1979 |
Drug treatment of arthritis in the elderly.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Immunosuppressive Agents; Indomethacin; Levamisole; Penicillamine; Phenylbutazone; Propionates; Salicylates | 1979 |
The antipyretic effect of UP 517-03 in the rabbit.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Body Temperature; Endotoxins; Indans; Indenes; Indomethacin; Male; Propionates; Rabbits; Salmonella | 1979 |
Mechanisms of platelet shape change, aggregation, and release induced by collagen, thrombin, or A23,187.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Collagen; Creatine Kinase; Dose-Response Relationship, Drug; Humans; Indomethacin; Malondialdehyde; Phosphocreatine; Platelet Aggregation; Rabbits; Serotonin; Thrombin | 1977 |
Modification, by aspirin and indomethacin, of the haemodynamic and prostaglandin releasing effects of E. coli endotoxin in the dog.
Topics: Animals; Aspirin; Blood Cell Count; Blood Platelets; Dogs; Drug Interactions; Endotoxins; Escherichia coli; Hemodynamics; Indomethacin; Male; Prostaglandins F; Time Factors | 1977 |
Effect of antipyretics on group A streptococcal pyrogenic exotoxin fever production and ability to enhance lethal endotoxin shock.
Topics: Animals; Aspirin; Cortisone; Drug Synergism; Endotoxins; Exotoxins; Fever; Indomethacin; Prostaglandins; Rabbits; Streptococcus pyogenes | 1978 |
The effect of indomethacin and ASA on in vivo induced white platelet arterial thrombus formation.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Epoprostenol; Indomethacin; Male; Mesenteric Arteries; Prostaglandins G; Prostaglandins H; Rats; Time Factors | 1978 |
Mechanism of inhibition of tumour growth by aspirin and indomethacin.
Topics: Animals; Antibodies, Neoplasm; Aspirin; Female; Fibrosarcoma; Hemolytic Plaque Technique; Immunosuppressive Agents; Indomethacin; Male; Mice; Sarcoma, Experimental | 1978 |
Pathophysiologic considerations in peptic ulcer disease.
Topics: ABO Blood-Group System; Adrenal Cortex Hormones; Aspirin; Bicarbonates; Environment; Female; Gastric Juice; Gastric Mucosa; Gastroesophageal Reflux; Humans; Indomethacin; Pancreas; Pepsin A; Peptic Ulcer; Pregnancy | 1979 |
The prostaglandins system and insulin release. Studies with the isolated perfused rat pancreas.
Topics: Animals; Aspirin; Furosemide; Glucose; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Quinacrine; Rats | 1979 |
Rabbit lung microsomes: a rapid method for assaying simultaneously drug effects on thromboxane and prostacyclin synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Burimamide; Dipyridamole; Epoprostenol; Hydralazine; Imidazoles; Indomethacin; Lung; Microsomes; Prostaglandins; Rabbits; Thromboxanes | 1979 |
Effects of prostaglandin synthesis inhibitors on human insulin secretion and carbohydrates tolerance.
Topics: Adult; Aspirin; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Humans; Ibuprofen; Indomethacin; Insulin; Insulin Secretion; Male; Middle Aged; Prostaglandin Antagonists; Prostaglandins E; Secretory Rate; Sodium Salicylate | 1979 |
Preventing the prostaglandin effect on dermal ischemia in the burn wound.
Topics: Animals; Aspirin; Burns; Female; Guinea Pigs; Indomethacin; Ischemia; Methylprednisolone; Prostaglandin Antagonists; Skin | 1978 |
On the mode of action and biochemical properties of anti-inflammatory drugs-II.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Glutathione; Hydroquinones; Indomethacin; Male; Mixed Function Oxygenases; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles | 1977 |
Relationship between multicentric reticulohistiocytosis and tuberculosis.
Topics: Arthritis; Aspirin; Diagnosis, Differential; Female; Humans; Indomethacin; Lymph Nodes; Lymphatic Diseases; Middle Aged; Mycobacterium tuberculosis; Tuberculosis, Lymph Node | 1977 |
Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin.
Topics: Acetylation; Aspirin; Binding Sites; Drug Synergism; Indomethacin; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Protein Binding | 1977 |
Influence of nonsteroidal anti-inflammatory drugs on ouabain toxicity.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Aspirin; Cyclooxygenase Inhibitors; Dogs; Female; Ibuprofen; Indomethacin; Male; Ouabain; Prostaglandin Antagonists; Tachycardia; Ventricular Fibrillation | 1977 |
Comparison of effects of aspirin and indomethacin on human platelet prostaglandin synthetase.
Topics: Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Male; Microsomes; Prostaglandin-Endoperoxide Synthases | 1977 |
Prostaglandin synthetase inhibitors in Bartter's syndrome. Effect on immunoreactive prostaglandin E excretion.
Topics: Adolescent; Adult; Aldosterone; Aspirin; Bartter Syndrome; Blood Pressure; Child; Cyclooxygenase Inhibitors; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Kidney; Middle Aged; Prostaglandins E; Renin | 1978 |
Pharmacology of the ductus arteriosus.
Topics: Aspirin; Chloroquine; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Pregnancy; Prostaglandins E; Pulmonary Circulation; Receptors, Prostaglandin | 1978 |
Prostaglandins and skin tumor promotion: inhibition of tumor promoter-induced ornithine decarboxylase activity in epidermis by inhibitors of prostaglandin synthesis.
Topics: Animals; Aspirin; Carboxy-Lyases; Cyclooxygenase Inhibitors; Enzyme Induction; Female; Flufenamic Acid; Indomethacin; Mice; Ornithine Decarboxylase; Phorbols; Prostaglandins E; Prostaglandins F; Skin; Tetradecanoylphorbol Acetate | 1977 |
Biotransformation and cardiovascular effects of arachidonic acid in the dog.
Topics: Animals; Arachidonic Acids; Aspirin; Biotransformation; Dogs; Female; Hemodynamics; Indomethacin; Male; Prostaglandins H; Thromboxane A2 | 1979 |
Contractile response of isolated rabbit aortic strips to unsaturated fatty acid peroxides.
Topics: Animals; Aorta, Thoracic; Aspirin; Atropine; Diphenhydramine; Drug Interactions; Fatty Acids, Unsaturated; Female; In Vitro Techniques; Indomethacin; Male; Methysergide; Peroxides; Phentolamine; Rabbits; Vasoconstriction | 1979 |
[Interactions and side-effects of non-steroid anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Drug Interactions; Drug Synergism; Humans; Indomethacin; Phenylbutazone; Salicylates | 1979 |
The effect of prostaglandins on the dermal microcirculation after burning, and the inhibition of the effect by specific pharmacological agents.
Topics: Animals; Aspirin; Burns; Female; Guinea Pigs; Indomethacin; Methylprednisolone; Microcirculation; Nicotinic Acids; Prostaglandin Antagonists; Prostaglandins; Skin | 1979 |
Rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Immunosuppressive Agents; Indomethacin; Joint Prosthesis; Lymphocytes; Penicillamine; Plasmapheresis; Pyrazoles; Synovectomy | 1979 |
Treatment of orthostatic hypotension with indomethacin.
Topics: Aspirin; Drug Evaluation; Humans; Hypotension, Orthostatic; Indomethacin | 1979 |
[Current status of vascular diseases and their treatment].
Topics: Arteriosclerosis; Aspirin; Clofibrate; Humans; Indomethacin; Sulfinpyrazone; Vasodilator Agents | 1979 |
Nonsteroidal antiinflammatory drugs: effect on pyloric sphincter and duodenogastric reflux.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Duodenum; Electrophysiology; Gastric Mucosa; Indomethacin; Phenylbutazone; Pressure; Pylorus | 1979 |
Indobufen, a new inhibitor of platelet aggregation. Studies in guinea pigs.
Topics: Animals; Aspirin; Blood Platelets; Blood Specimen Collection; Dipyridamole; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Isoindoles; Phenylbutyrates; Platelet Aggregation; Prostaglandins; Prothrombin Time; Serotonin; Thrombin; Thromboxane A2; Time Factors | 1979 |
[Antagonist of prostaglandin synthesis in the treatment of dysmenorrhea].
Topics: Aspirin; Dysmenorrhea; Female; Humans; Indomethacin; Naproxen; Prostaglandin Antagonists | 1979 |
Inhibition of human leucocytes locomotion by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Neutrophils; Salicylates | 1979 |
Inhibition by aspirin of gastrointestinal toxicity induced by indomethacin in polyarthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Indomethacin; Intestine, Small; Lethal Dose 50; Male; Rats; Stomach | 1979 |
A possible role of arachidonic acid in human neutrophil aggregation and degranulation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Aspirin; Cell Movement; Cytoplasmic Granules; Humans; In Vitro Techniques; Indomethacin; Neutrophils | 1979 |
Drugs for dysmenorrhea.
Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbuphine; Naproxen; Time Factors | 1979 |
Studies on the effects of anti-inflammatory action of benzoyl-hydrotropic acid (ketoprofen) and other drugs, with special reference to prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Foot; Indomethacin; Ketoprofen; Male; Phenylpropionates; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats | 1979 |
Studies on the hyperthermic response of beta-endorphin in mice.
Topics: Analgesics; Animals; Aspirin; Body Temperature; Cations, Divalent; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalins; Environment; Indomethacin; Mice; Mice, Inbred ICR; Morphine; Naloxone; Time Factors | 1979 |
Vascular responsiveness to pressor agents during human pregnancy.
Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregnancy; Pregnancy Complications, Hematologic; Renin; Sickle Cell Trait; Theophylline; Vasomotor System | 1979 |
Prostaglandins in the pathogenesis of the generalized Shwartzman reaction.
Topics: Animals; Aspirin; Bradykinin; Cortisone; Endotoxins; Female; Indomethacin; Male; Pregnancy; Prostaglandins; Prostaglandins A; Prostaglandins E; Rabbits; Rats; Salmonella typhi; Shwartzman Phenomenon | 1979 |
Escape from sodium and potassium retaining actions of aspirin-like drugs used in a patient with Bartter's syndrome.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Prostaglandins; Sodium; Spironolactone | 1979 |
Characteristics of histamine tachyphylaxis in canine tracheal smooth muscle.
Topics: Acetylcholine; Airway Resistance; Animals; Aspirin; Autonomic Agents; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Indomethacin; Male; Mefenamic Acid; Muscle, Smooth; Oxyphenbutazone; Prostaglandins; Tachyphylaxis; Time Factors; Trachea | 1979 |
Role of arachidonic acid derivatives in neutrophil aggregation: a hypothesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Buffers; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Indomethacin; Neutrophils; Phenylalanine; Prostaglandin Antagonists | 1979 |
Inhibition of the neutrophil oxidative response to a chemotactic peptide by inhibitors of arachidonic acid oxygenation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antimycin A; Arachidonic Acids; Aspirin; Chemotaxis; Cytochalasin B; Digitonin; Dipeptides; Fatty Acids, Unsaturated; Guinea Pigs; Indomethacin; Kinetics; Methionine; N-Formylmethionine; Neutrophils; Oxygen Consumption | 1979 |
Paracetamol potentiates acetylsalicylate in inhibiting prostaglandin synthesis.
Topics: Acetaminophen; Animals; Aspirin; Cricetinae; Depression, Chemical; Drug Synergism; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Muscle Tonus; Prostaglandins; Rats; Seminal Vesicles | 1979 |
Prostaglandins and the contractile action of bradykinin on the longitudinal muscle of rat isolated ileum.
Topics: Animals; Aspirin; Bradykinin; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats | 1979 |
[A clinical study of pathophysiological feature of "Bartter's syndrome" (author's transl)].
Topics: Adult; Angiotensin II; Aspirin; Bartter Syndrome; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Electrolytes; Female; Humans; Hyperaldosteronism; Hypokalemia; Ibuprofen; Indomethacin; Infant; Male; Renin; Water-Electrolyte Balance | 1979 |
Changes in coronary vascular resistance associated with prolonged hypoxia in isolated rat hearts: a possible role of prostaglandins.
Topics: Aging; Animals; Aspirin; Chloroquine; Coronary Circulation; Coronary Disease; In Vitro Techniques; Indomethacin; Male; Procaine; Propranolol; Prostaglandins; Rats; Time Factors; Vascular Resistance | 1979 |
Comparisons of tolerability findings in international clinical trials.
Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Tests; Humans; Ibuprofen; Indomethacin; International Cooperation; Naproxen; Phenylacetates; Time Factors | 1979 |
Studies on two new derivatives of N-aralkyl-O-ethoxybenzamides: Part III-pharmacological & biochemical studies on their anti-arthritic activity in rat.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzamides; Connective Tissue; Indomethacin; Male; Phenylbutazone; Rats | 1979 |
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Digestive System; Ibuprofen; Indomethacin; Irritants; Male; Phenylbutazone; Rats; Stomach Ulcer; Thiazoles | 1979 |
Synthesis and anti-inflammatory properties of some pyrrolo(1H,3H)[3,4-d]pyrimidin-2-ones and pyrrolo(1H,6H)[3,4-d]pyrimidin-2-ones.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Female; Indomethacin; Male; Mice; Pyrimidinones; Pyrroles; Rats | 1979 |
Medical treatment of the ductus arteriosus.
Topics: Animals; Aspirin; Coronary Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetal Heart; Formaldehyde; Heart Defects, Congenital; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Oxygen; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Sheep | 1977 |
[Pharmacological studies of 2-(5H-(1)benzopyrano[2,3-b]pyridin-7-yl)propionic acid (Y-8004). (3) Its interaction with anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Edema; Hydrocortisone; Indomethacin; Lethal Dose 50; Male; Phenylbutazone; Prednisolone; Propionates; Pyridines; Rats | 1977 |
Prostaglandins and myoblast fusion.
Topics: Animals; Aspirin; Cell Fusion; Chick Embryo; Dose-Response Relationship, Drug; Indomethacin; Muscles; Prostaglandins E | 1977 |
In vivo inhibition of prostaglandin synthesis in rabbit kidney by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Dose-Response Relationship, Drug; Indomethacin; Injections, Intravenous; Kidney; Kidney Medulla; Male; Naproxen; Prostaglandins E; Prostaglandins F; Rabbits; Time Factors | 1978 |
Enhancement of natural and antibody-dependent lymphocyte cytotoxicity by drugs which inhibit prostaglandin production by tumor target cells.
Topics: Antibody-Dependent Cell Cytotoxicity; Aspirin; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Humans; Indomethacin; Lymphocytes; Neoplasms, Experimental; Prostaglandin Antagonists; Thiazoles; Time Factors | 1978 |
PDAs, prostaglandins, and RLF.
Topics: Aspirin; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Pregnancy; Prostaglandins E; Retinopathy of Prematurity | 1978 |
Indomethacin-induced asthma in aspirin-sensitive patients.
Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin | 1977 |
Platelet effects of arachidonic acid in dog blood. I. Lack of involvement of cyclo-oxygenase in the in vivo situation.
Topics: Adenosine Diphosphate; Ancrod; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Indomethacin; Linoleic Acids; Male; Oxygenases; Platelet Aggregation; Prostaglandins E; Pyrogallol; Thrombin; Thrombocytopenia | 1977 |
[Role of prostaglandins in blood pressure regulation].
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Vessels; Diet; Epinephrine; Female; Hypertension; Indomethacin; Male; Norepinephrine; Prostaglandin Antagonists; Prostaglandins E; Rabbits; Rats; Sodium Chloride | 1977 |
Tumor-mediated immunosuppression: prevention by inhibitors of prostaglandin synthesis.
Topics: Animals; Antibody Formation; Aspirin; Cell Line; Erythrocytes; Flufenamic Acid; Immunosuppression Therapy; Indomethacin; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Prostaglandin Antagonists; Spleen | 1977 |
[Indomethacin-induced asthma (author's transl)].
Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin; Male; Middle Aged | 1977 |
Influence of indomethacin and aspirin on the contractile effects of prostaglandin F2alpha (PGF2alpha) at different Ca++ concentrations (experiments on guinea-pig ileum).
Topics: Animals; Aspirin; Calcium; Cations, Divalent; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Time Factors | 1977 |
Epidermal antihyperplastic effects of contact antiphlogistics.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bufexamac; Fluocinolone Acetonide; Guinea Pigs; Hydrocortisone; Hyperplasia; Indazoles; Indomethacin; Oxyphenbutazone; Palmitates; Phenylbutazone; Skin | 1978 |
Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Depression, Chemical; Granuloma; Hydrocortisone; In Vitro Techniques; Indomethacin; Male; Prostaglandins F; Rats; Thromboxane B2; Thromboxanes | 1978 |
Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoxazines; Drug Evaluation, Preclinical; Edema; Hydrocortisone; Indomethacin; Isoxazoles; Male; Oxazines; Phenylbutazone; Rats; Salicylates | 1978 |
[Platelet-inhibiting drugs].
Topics: Anti-Bacterial Agents; Aspirin; Dextrans; Dipyridamole; Hemorrhage; Humans; Indomethacin; Platelet Aggregation; Sulfinpyrazone; Thrombosis | 1978 |
[The metabolic regulation of the retinal blood flow and the role of prostaglandins (author's transl)].
Topics: Animals; Arterioles; Aspirin; Histamine; Hypercapnia; Hypoxia; Indomethacin; Prostaglandins E; Regional Blood Flow; Retina; Retinal Vessels; Vasodilation | 1978 |
In vivo method for quantitation for anti-platelet potency of drugs.
Topics: Animals; Aspirin; Blood Coagulation; Cats; Fibrinolytic Agents; In Vitro Techniques; Indoles; Indomethacin; Platelet Aggregation; Pyridines; Rabbits; Time Factors | 1978 |
[Still's disease (juvenile chronic polyarthritis) in adulthood].
Topics: Adolescent; Adult; Age Factors; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Male | 1978 |
Sigma SR, a new method of measuring erythrocyte sedimentation rate. Its value in studying the action and interactions of non-steroidal anti-inflammatory agents.
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Sedimentation; Body Temperature; Drug Interactions; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1978 |
Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors.
Topics: Animals; Ascaris; Aspirin; Asthma; Dogs; Hypersensitivity; Hypoxia; Indomethacin; Lung; Oxygen; Prostaglandin Antagonists; Vasoconstriction | 1978 |
[Effect of aspirin and indomethacin on changes caused by Pateurella multocida toxins in calves].
Topics: Animals; Aspirin; Bacterial Toxins; Cattle; Female; Indomethacin; Male; Pasteurella; Poisoning | 1978 |
Management of premature labor.
Topics: Aspirin; Bed Rest; Betamethasone; Estrogens; Ethanol; Female; Fetal Membranes, Premature Rupture; Glucocorticoids; Humans; Hydroxyprogesterones; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Isoxsuprine; Magnesium Sulfate; Obstetric Labor, Premature; Oxytocin; Pregnancy; Progesterone; Prostaglandins; Respiratory Distress Syndrome, Newborn | 1978 |
Influence of aspirin and indomethacin on variability of alveolar hypoxic vasoconstriction.
Topics: Animals; Aspirin; Dogs; Hypoxia; In Vitro Techniques; Indomethacin; Nitrogen; Oxygen; Pulmonary Alveoli; Respiration; Vasoconstriction | 1978 |
Prostaglandin the osmoregulatory role of prolactin in a teleost.
Topics: Animals; Aspirin; Chlorides; Fishes; Indomethacin; Prolactin; Prostaglandins; Prostaglandins E; Water-Electrolyte Balance | 1978 |
Stimulation of microsomal prostaglandin synthesis by a vasoactive material isolated from blood plasma.
Topics: Animals; Arachidonic Acids; Aspirin; Depression, Chemical; Drug Synergism; Epinephrine; Hemin; Indomethacin; Kidney Medulla; Male; Microsomes; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Rabbits; Stimulation, Chemical; Tryptophan; Vasoconstrictor Agents | 1978 |
Studies on the role of prostaglandins in the regulation of retinal blood flow.
Topics: Animals; Arterioles; Aspirin; Fluorescein Angiography; Hypercapnia; Hypoxia; Indomethacin; Prostaglandins E; Regional Blood Flow; Retinal Artery; Swine; Vasodilation | 1978 |
Reduction by indomethacin of the degeneration increase in outflow facility after superior cervical ganglionectomy in the rabbit.
Topics: Animals; Aqueous Humor; Aspirin; Eye; Ganglia, Autonomic; Indomethacin; Intraocular Pressure; Male; Rabbits; Suppositories | 1978 |
[Gastrointestinal diseases caused by drugs, especially by anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Dogs; Gastrointestinal Diseases; Indomethacin; Peptic Ulcer; Rats | 1978 |
Influence of surgical sympathectomy on gastric secretion and ulceration in rats.
Topics: Acetates; Animals; Aspirin; Digestive System; Gastric Juice; Indomethacin; Male; Rats; Reserpine; Serotonin; Stomach Ulcer; Stress, Physiological; Sympathectomy | 1978 |
Platelet aggregation and vasoconstriction in undamaged microvessels on cerebral surface adjacent to brain traumatized by a penetrating needle.
Topics: Animals; Arterioles; Aspirin; Brain Injuries; Dipyridamole; Indomethacin; Male; Mice; Pia Mater; Platelet Aggregation; Vasoconstriction | 1978 |
[Asthmatic reaction provoked by non-steroid antirheumatics. With special attention to cross reactions with acetylsalicylic acid].
Topics: Adult; Age Factors; Aged; Aspirin; Denmark; Drug Hypersensitivity; Drug Interactions; Female; Humans; Indomethacin; Male; Middle Aged; Sex Factors | 1978 |
[Effect of acetylsalicylic acid and indomethacin on lipid metabolism].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Arthritis, Rheumatoid; Aspirin; Female; Humans; Indomethacin; Lipid Metabolism; Male; Middle Aged | 1978 |
Effects of cold or restraint on incidence of gastric ulceration induced in rats by ulcerogenic drugs.
Topics: Animals; Aspirin; Cimetidine; Cold Temperature; Female; Histamine; Indomethacin; Male; Phenylbutazone; Rats; Restraint, Physical; Stomach Ulcer; Time Factors | 1978 |
Inhibitory effect of tiaramide on ADP-induced aggregation in rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Aspirin; Benzothiazoles; Indomethacin; Piperazines; Platelet Aggregation; Rabbits; Thiazoles | 1978 |
Pharmacological alterations in the clotting mechanism: use in microvascular surgery.
Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Chlorpromazine; Dextrans; Drug Combinations; Fibrinolysis; Fibrinolytic Agents; Hemostasis; Heparin; Humans; Indomethacin; Microsurgery; Platelet Adhesiveness; Platelet Aggregation; Poloxalene; Rabbits; Reserpine; Vascular Surgical Procedures | 1978 |
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Phenylbutazone | 1978 |
Aspirin- and indomethacin-induced ulcers and their antagonism by antihistamines.
Topics: Animals; Aspirin; Cold Temperature; Corticosterone; Histamine Antagonists; Indomethacin; Male; Rats; Restraint, Physical; Stomach Ulcer; Stress, Physiological; Time Factors | 1978 |
[Irritative activity of antiinflammatory agents, betamethasone 17-valerate, beclomethasone 17, 21-dipropionate, betamethasone 17, 21-dipropionate, or indomethacin on the gastrointestinal tract in rats and dogs (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Beclomethasone; Betamethasone; Betamethasone Valerate; Chronic Disease; Digestive System; Dogs; Indomethacin; Irritants; Male; Rats; Stomach Ulcer | 1978 |
[Comparative studies on gastrointestinal damage induced by non-steroidal anti-inflammatory drugs in rats (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Male; Phenylbutazone; Rats; Stomach Ulcer | 1978 |
Analysis of the bradykinin response in dogs and its antagonism by analgesic drugs.
Topics: Analgesics; Animals; Aspirin; Bradykinin; Dextroamphetamine; Dogs; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Meperidine; Methadone; Phenylbutazone | 1978 |
Prostaglandin mediated relaxation of coronary artery strips under hypoxia.
Topics: Acetylcholine; Animals; Aspirin; Cattle; Coronary Vessels; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxygen; Potassium Chloride; Prostaglandins; Vasoconstriction; Vasodilation | 1978 |
Inhibition of prostaglandin synthesis in rat brain.
Topics: Acetaminophen; Animals; Aspirin; Brain; Diclofenac; Dose-Response Relationship, Drug; Indomethacin; Male; Naproxen; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rats; Time Factors | 1978 |
Distention ulcer as a model for testing of drugs for ulcerogenic side effects.
Topics: Animals; Aspirin; Disease Models, Animal; Hydrochloric Acid; Indomethacin; Male; Rats; Stomach; Stomach Ulcer; Stress, Physiological; Time Factors | 1978 |
[Rheumatoid disease in children. Current acquisitions and considerations of the pediatrist].
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Chloroquine; Cyclophosphamide; Drug Therapy, Combination; Female; Gold; Humans; Indomethacin; Male; Penicillamine; Phenylbutazone; Wissler's Syndrome | 1978 |
Problem of patent ductus arteriosus in premature infants.
Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; Heart Rate; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Oxygen; Pulmonary Circulation; Respiratory Distress Syndrome, Newborn; Vascular Resistance | 1978 |
Ketoprofen experiences.
Topics: Aspirin; Humans; Indomethacin; Ketoprofen; Phenylbutazone; Phenylpropionates | 1978 |
Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors.
Topics: Aspirin; Asthma; Fenoprofen; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged | 1978 |
Effects of concomitant aspirin administration on the pharmacokinetics of indomethacin in man.
Topics: Adult; Aspirin; Biotransformation; Drug Interactions; Half-Life; Humans; Indomethacin; Intestinal Absorption; Kinetics; Male; Salicylates; Statistics as Topic; Tissue Distribution | 1978 |
Indomethacin and lysine acetylsalicylate in rats with autologous nephrotoxic serum nephritis. Biochemical and morphological studies.
Topics: Animals; Aspirin; Basement Membrane; Disease Models, Animal; Female; Glomerulonephritis; Immune Sera; Indomethacin; Kidney Glomerulus; Lysine; Proteinuria; Rabbits; Rats | 1978 |
Relationship between inhibition of prostaglandin beta-oxidation and deenergization of mitochondrial membranes.
Topics: Animals; Aspirin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlorpromazine; Dinitrophenols; Imipramine; Indomethacin; Mitochondria, Liver; Mitochondrial Swelling; Oxidation-Reduction; Oxidative Phosphorylation; Prostaglandins E; Rats; Salicylates | 1978 |
The effect of acetylsalicylic acid and indomethacin on rabbit platelet adherence to collagen and the subendothelium in the presence of a low or high hematocrit.
Topics: Animals; Aorta, Thoracic; Aspirin; Collagen; Endothelium; Hematocrit; Indomethacin; Platelet Adhesiveness; Rabbits | 1978 |
Possible role of arachidonic acid and its metabolites in mediator release from rat mast cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Aspirin; Cattle; Fatty Acids, Nonesterified; Histamine; Indomethacin; Kinetics; Male; Mast Cells; Rats; Serum Albumin, Bovine | 1979 |
The effects of aspirin and indomethacin on the ocular response to circulating bacterial endotoxin in the rabbit.
Topics: Animals; Aspirin; Disease Models, Animal; Dogs; Endotoxins; Escherichia coli; Eye; Female; Indomethacin; Male; Prostaglandins; Rabbits; Uveitis, Anterior | 1976 |
[Effect of acetylsalicylic acid on experimentally induced endotoxin reactions in swine].
Topics: Animals; Aspirin; Drug Interactions; Endotoxins; Escherichia coli; Indomethacin; Shock, Septic; Swine; Swine Diseases | 1976 |
Correlation between anti-inflammatory properties and inhibition of prostaglandin biosynthesis in vitro.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Cyclooxygenase Inhibitors; Depression, Chemical; In Vitro Techniques; Indomethacin; Male; Microsomes; Prostaglandin Antagonists; Prostaglandins; Rats; Seminal Vesicles | 1975 |
The significance of inhibition of prostaglandin synthesis in the selection of non-steroidal anti-inflammatory agents.
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Cyclooxygenase Inhibitors; Edema; Flufenamic Acid; Indomethacin; Male; Mefenamic Acid; Oxyphenbutazone; Phenylacetates; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Rats; Structure-Activity Relationship | 1975 |
Rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Cyclophosphamide; Female; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Ibuprofen; Immunosuppressive Agents; Indomethacin; Middle Aged; Phenylbutazone; Physical Therapy Modalities; Prednisolone; Referral and Consultation | 1975 |
Acetylation of prostaglandin synthase by aspirin.
Topics: Acetylation; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Chemical Phenomena; Chemistry; Fatty Acids, Nonesterified; Humans; Indomethacin; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Molecular Weight; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles | 1975 |
Radioimmunoassay of main urinary metabolite of prostaglandin F2alpha.
Topics: Animals; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Depression, Chemical; Flufenamic Acid; Immune Sera; Indomethacin; Prostaglandins F; Rabbits; Radioimmunoassay; Rats; Time Factors | 1975 |
Prostaglandin synthetase systems of rabbit tissues and their inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Female; Flufenamic Acid; In Vitro Techniques; Indomethacin; Microsomes; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Rabbits | 1976 |
Potentiation of the anti-inflammatory and analgesic activity of aspirin by caffeine in the rat.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Caffeine; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Indomethacin; Inflammation; Male; Phenylbutazone; Rats; Salicylates | 1976 |
Suppression of thyrotropic hormone secretion by prostaglandin synthesis inhibitors.
Topics: Animals; Aspirin; Feedback; Female; Indomethacin; Pituitary Gland; Prostaglandin Antagonists; Prostaglandins; Rats; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone | 1976 |
Alteration of canine renal vascular response to hemorrhage by inhibitors of prostaglandin synthesis.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Depression, Chemical; Dogs; Hemorrhage; Hypotension; Indomethacin; Kidney; Microspheres; Mixed Function Oxygenases; Prostaglandin Antagonists; Prostaglandins; Regional Blood Flow | 1976 |
Prostaglandins and the hemodynamic course of endotoxin shock.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Disease Models, Animal; Haplorhini; Hemodynamics; Indomethacin; Lung; Male; Papio; Prostaglandins E; Prostaglandins F; Shock, Septic; Time Factors | 1976 |
Inhibitory effects of various drugs on dual asthmatic responses in wheat flour-sensitive subjects.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Cromolyn Sodium; Diethylcarbamazine; Flour; Forced Expiratory Volume; Humans; Indomethacin; Male; Prednisolone; Time Factors; Triprolidine; Triticum | 1976 |
Anti-inflammatory drugs, prostaglandins and leucocyte migration.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Exudates and Transudates; Female; Indomethacin; Leukocytes; Phenylbutazone; Plasma; Prostaglandins; Rats | 1976 |
Prostaglandin synthetase activity from human rheumatoid synovial microsomes. Effect of 'aspirin-like' drug therapy.
Topics: Adult; Aged; Arachidonic Acids; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Synovial Membrane | 1976 |
The effect of anti-inflammatory agents on human synovial fibroblast prostaglandin synthetase.
Topics: Anti-Inflammatory Agents; Aspirin; Catecholamines; Cells, Cultured; Edetic Acid; Fibroblasts; Gold; Humans; Hydrocortisone; Indicators and Reagents; Indomethacin; Methods; Mixed Function Oxygenases; Penicillamine; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Sulfhydryl Compounds; Synovial Membrane | 1976 |
Inhibition of prostaglandin biosynthesis by tolfenamic acid in vitro.
Topics: Animals; Arachidonic Acids; Aspirin; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Female; Indomethacin; Kidney; Kidney Medulla; Male; Microsomes; ortho-Aminobenzoates; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rabbits | 1976 |
Antiinflammatory agents and inhibition of ocular prostaglandin synthetase.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Conjunctiva; Cyclooxygenase Inhibitors; Epinephrine; Eye Diseases; Glutathione; Hydroquinones; Indomethacin; Inflammation; Iris; Kidney Medulla; Male; Microsomes; Mixed Function Oxygenases; Prostaglandins E; Rabbits; Seminal Vesicles; Sheep | 1976 |
Inhibition of prostaglandin synthetase by tolmetin (Tolectin, McN-2559), a new non-steroidal anti-inflammatory agent.
Topics: Animals; Aspirin; Cattle; Cyclooxygenase Inhibitors; Indomethacin; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Prostaglandins E; Pyrroles; Seminal Vesicles; Structure-Activity Relationship; Tolmetin | 1976 |
[The effect of prostaglandin F2alpha on pregnancy in rats and attempts to counteract its abortifacient action].
Topics: Abortifacient Agents; Animals; Aspirin; Dose-Response Relationship, Drug; Female; Gestational Age; Indomethacin; Pregnancy; Progesterone; Prostaglandins F; Rats | 1976 |
Design of a new prostaglandin synthetase inhibitors in a group of N-(2-carboxyphenyl)phenoxyacetamides and their antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Cyclooxygenase Inhibitors; Glycolates; In Vitro Techniques; Indomethacin; Mixed Function Oxygenases; Phenoxyacetates; Protein Binding; Rats; Serum Albumin; Structure-Activity Relationship | 1976 |
Comparative evaluation of the inhibitory effects of aspirin-like drugs on prostaglandin production by human platelets and synovial tissue.
Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Female; Fenoprofen; Humans; Hydrocortisone; Indomethacin; Kinetics; Male; Middle Aged; Mixed Function Oxygenases; Phenylpropionates; Prostaglandins F; Synovial Membrane | 1976 |
The biosynthesis of prostaglandins by brain tissue in vitro.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetaminophen; Adrenochrome; Animals; Arachidonic Acids; Aspirin; Cats; Cerebral Cortex; Cyclooxygenase Inhibitors; Dopamine; Humans; In Vitro Techniques; Indomethacin; Norepinephrine; Prostaglandins E; Prostaglandins F; Rats; Species Specificity | 1976 |
Inhibition by drugs of the stimulation of prostaglandin biosynthesis induced by apomorphine.
Topics: Animals; Antidepressive Agents; Antiemetics; Apomorphine; Aspirin; Cattle; Cell-Free System; Cyclooxygenase Inhibitors; Ergotamine; Indomethacin; Male; Prostaglandins; Seminal Vesicles | 1976 |
Effect of concurrent administration of aspirin, indomethacin or hydrocortisone with gold sodium thiomalate against adjuvant-induced arthritis in the rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Blood Sedimentation; Drug Therapy, Combination; Gold; Gold Sodium Thiomalate; Hydrocortisone; Indomethacin; Male; Mycobacterium tuberculosis; Rats; Time Factors | 1976 |
Ductal manipulation--a note of caution.
Topics: Aspirin; Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Oxygen; Prostaglandins E; Prostaglandins F | 1977 |
Breakthrough in treatment of patent ductus arteriosus.
Topics: Aspirin; Chloroquine; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Prostaglandins; Prostaglandins F | 1977 |
[Indications for pharmacological treatment of children with rheumatoid arthritis and an evaluation of therapeutic results].
Topics: Adrenal Cortex Hormones; Age Factors; Arthritis, Juvenile; Aspirin; Child; Drug Evaluation; Gold; Humans; Immunosuppressive Agents; Indomethacin | 1977 |
Vasoconstrictor response to arachidonic acid in the isolated hind limb of the dog.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Dogs; Drug Interactions; Female; Hindlimb; Indomethacin; Male; Norepinephrine; Phentolamine; Prostaglandins E; Prostaglandins F; Vasomotor System | 1977 |
[Antiphiogistic drugs. Sudies on the pharmocokinetics of anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Indomethacin; Injections, Intra-Articular; Phenylbutazone; Rabbits; Synovitis | 1977 |
Failure to demonstrate involvement of prostaglandins in the immune expulsion of Trichostrongylus colubriformis from the intestine of guinea pigs.
Topics: Animals; Aspirin; Guinea Pigs; Indomethacin; Intestines; Prostaglandins; Trichostrongyloidiasis; Trichostrongylosis | 1977 |
Effects of prostaglandin E2 and prostaglandin inhibitors on adrenal regeneration hypertension.
Topics: Adrenal Glands; Adrenalectomy; Animals; Aspirin; Female; Hypertension; Indomethacin; Nephrectomy; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Rats; Regeneration; Sodium Chloride | 1977 |
Actions of bradykinin on isolated cerebral and peripheral arteries.
Topics: Animals; Arteries; Aspirin; Bradykinin; Carotid Artery, External; Carotid Artery, Internal; Cats; Cerebral Arteries; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Indomethacin; Male; Methysergide; Phentolamine; Potassium; Prostaglandins E; Prostaglandins F; Rabbits; Receptors, Drug; Vasomotor System | 1977 |
Modulation of phagocytosis by and lysosomal enzyme secretion from guinea-pig neutrophils: effect of nonsteroid anti-inflammatory agents and prostaglindins.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Fenoprofen; Glucuronidase; Guinea Pigs; In Vitro Techniques; Indomethacin; Lysosomes; Naproxen; Neutrophils; Phagocytosis; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F | 1977 |
[Further studies of the action of an anti-inflammatory agent recently used in therapy].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Indomethacin; Inflammation; Phenylbutazone; Rats; Thiazoles | 1977 |
Vasodilatory action of arachidonic acid in humans following indomethacin treatment.
Topics: Arachidonic Acids; Aspirin; Drug Synergism; Forearm; Humans; Indomethacin; Male; Oleic Acids; Regional Blood Flow; Vasomotor System | 1977 |
Role of prostaglandins in alveolar hypoxic vasoconstriction.
Topics: Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Hypoxia; Indomethacin; Intubation, Intratracheal; Prostaglandins; Pulmonary Alveoli; Pulmonary Circulation; Pulmonary Ventilation; Vascular Resistance; Vasomotor System | 1977 |
Migrating action potential complex of cholera: a possible prostaglandin-induced response.
Topics: Action Potentials; Animals; Aspirin; Bacterial Toxins; Female; Gastrointestinal Motility; Ileum; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Rabbits; Vibrio cholerae | 1977 |
Effects of antiinflammatory agents on the acute response of immune synovitis in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Colchicine; Disease Models, Animal; Dose-Response Relationship, Immunologic; Glucuronidase; Indomethacin; Lysosomes; Methods; Niflumic Acid; Phenylbutazone; Prednisolone; Rabbits; Serum Albumin, Bovine; Synovitis; Triamcinolone Acetonide | 1977 |
Effect of pretreatment with antiinflammatory agents on paraquat toxicity in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Breath Tests; Cytosol; Ethane; Glutathione Peroxidase; Glutathione Reductase; Hydrocortisone; Indomethacin; Lipid Metabolism; Lung; Male; Paraquat; Peroxides; Rats; Superoxide Dismutase; Time Factors | 1977 |
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Peptic Ulcer; Phenylbutazone; Tolmetin | 1977 |
Effects of prostaglandins on the peristaltic reflex of the guinea-pig ileum.
Topics: Animals; Aspirin; Flufenamic Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Indomethacin; Peristalsis; Phenylbutazone; Prostaglandins E | 1977 |
Prostaglandin synthesis inhibition restores hypoxic pulmonary vasoconstriction.
Topics: Animals; Aspirin; Blood Pressure; Dogs; Hypoxia; Indomethacin; Prostaglandins; Pulmonary Artery; Pulmonary Circulation | 1977 |
Pharmacokinetics of salicylate and indomethacin in coeliac disease.
Topics: Adult; Aspirin; Celiac Disease; Female; Humans; Indomethacin; Kinetics; Male; Middle Aged; Salicylates; Time Factors | 1977 |
Self regulation of growth by human diploid fibroblasts via prostaglandin production.
Topics: Aspirin; Cell Division; Cell Line; Diploidy; Fibroblasts; Hydrocortisone; Indomethacin; Prostaglandins; Prostaglandins E; Prostaglandins F | 1977 |
Analogues of anthracene, phenanthrene, and benzoflavone inhibit prostaglandin biosynthesis by cells in culture.
Topics: Animals; Anthracenes; Aspirin; Cells, Cultured; Dogs; Fibroblasts; Flavonoids; Humans; Indomethacin; Mice; Molecular Conformation; Phenanthrenes; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F | 1977 |
Lack of correlation between glutathione peroxidase activities and slsceptibility to O2 toxicity in rat lungs.
Topics: Animals; Aspirin; Cytosol; Glutathione Peroxidase; Hydrocortisone; In Vitro Techniques; Indomethacin; Lung; Male; Oxygen; Peroxidases; Rats | 1977 |
Alteration of Hepatic microsomal enzyme systems and the lethal action of non-steroidal anti-arthritic drugs in acute and chronic models of inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Carrageenan; Chronic Disease; Disease Models, Animal; Indomethacin; Inflammation; Lethal Dose 50; Male; Microsomes, Liver; Phenylbutazone; Rats; Sleep; Time Factors | 1977 |
The effect of sulindac and sulindac metabolites on arachidonate-induced lethality in rabbits: effect on human, guinea pig, dog, and rat platelet activity.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Collagen; Dogs; Epinephrine; Guinea Pigs; Humans; Indenes; Indomethacin; Platelet Aggregation; Rats; Sulfides; Sulfones; Sulfoxides | 1977 |
New experimental model for the primary evaluation of topical contra-inflammatory agents.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Clobetasol; Croton Oil; Dermatitis, Contact; Drug Evaluation; Ear, External; Flumethasone; Hydrocortisone; Indomethacin; Rabbits; Salicylates; Skin | 1977 |
Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Fiber Optic Technology; Gastritis; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged | 1977 |
Arthritis of the spine: early diagnosis and management of ankylosing spondylitis.
Topics: Adult; Aged; Aspirin; Child; Diagnosis, Differential; Female; Humans; Indomethacin; Male; Middle Aged; Physical Examination; Physical Therapy Modalities; Prognosis; Spondylitis, Ankylosing | 1977 |
Investigations on prostatic adenocarcinomas in rats.
Topics: Adenocarcinoma; Anesthetics; Animals; Aspirin; Cell Line; Female; Immunotherapy; Indomethacin; Lung Neoplasms; Male; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Propionibacterium acnes; Prostatic Neoplasms; Rats; Transplantation, Homologous | 1977 |
[Skin vasoconstriction effect of contact antiphlogistics].
Topics: Anti-Inflammatory Agents; Aspirin; Bufexamac; Humans; Hydrocortisone; Indomethacin; Oxyphenbutazone; Salicylates; Skin; Vasoconstriction | 1977 |
Effect of indomethacin and aspirin on gastric blood flow and acid secretion.
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Drug Interactions; Gastric Juice; Indomethacin; Male; Microspheres; Pentagastrin; Regional Blood Flow; Stomach | 1977 |
A profile of the gastrointestinal toxicity of aspirin, indomethacin, oxaprozin, phenylbutazone, and fentiazac in arthritic and Lewis normal rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Body Weight; Gastrointestinal Diseases; Indomethacin; Intestine, Small; Male; Oxazoles; Phenylbutazone; Propionates; Rats; Stomach; Thiazoles; Time Factors | 1977 |
Prostaglandin-induced diarrhoea.
Topics: Aspirin; Child, Preschool; Diarrhea; Female; Humans; Indomethacin; Prostaglandins | 1977 |
Malondialdehyde formation as an indicator of prostaglandin production by human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Malonates; Malondialdehyde; Platelet Aggregation; Prostaglandins; Thrombin | 1976 |
Influence of nonsteroidal anti-inflammatory agents on myocardial ischemia in the cat.
Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aspirin; Blood Pressure; Cats; Coronary Disease; Coronary Vessels; Creatine Kinase; Female; Indomethacin; Liver; Lysosomes; Male; Meclofenamic Acid; Muscle Tonus; Myocardium; Papillary Muscles; Prostaglandins; Proteins | 1976 |
Oral antipyretic therapy.
Topics: Acetaminophen; Administration, Oral; Aminopyrine; Aspirin; Child; Child, Preschool; Drug Evaluation; Fever; Humans; Ibuprofen; Indomethacin; Phenylpropionates | 1976 |
Endogenous prostaglandins and mechanical tension in canine trachealis muscle.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Atropine; Carbachol; Dogs; Indomethacin; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ouabain; Phenoxybenzamine; Phentolamine; Potassium; Propranolol; Prostaglandins E; Prostaglandins F; Scopolamine; Trachea | 1976 |
Intrinsic prostaglandin release. A mediator of anoxia-induced relaxation in an isolated coronary artery preparation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arteries; Aspirin; Cattle; Coronary Vessels; Hypoxia; Indomethacin; Muscle Contraction; Muscle, Smooth; Oxygen; Partial Pressure; Prostaglandins; Secretory Rate; Time Factors | 1976 |
Dermatopharmacology of salicylic acid. III. Topical contra-inflammatory effect of salicylic acid and other drugs in animal experiments.
Topics: Administration, Topical; Animals; Aspirin; Bufexamac; Dermatitis; Flumethasone; Fluocinolone Acetonide; Guinea Pigs; Hydrocortisone; Indomethacin; Male; Phenylbutazone; Salicylates | 1976 |
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin | 1976 |
A novel relationship between plasma kininogen and rheumatoid.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Female; Humans; Indomethacin; Kininogens; Male; Middle Aged; Placebos; Time Factors | 1976 |
Activity of anti-inflammatory drugs on an experimental model of osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cartilage, Articular; Catalase; Disease Models, Animal; Glycosaminoglycans; Indomethacin; Male; Methods; Methylprednisolone; Osteoarthritis; Papain; Rabbits; Time Factors | 1976 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
Human breast tumour-induced osteolysis and prostaglandins.
Topics: Aspirin; Bone Resorption; Breast Neoplasms; Female; Humans; Indomethacin; Osteolysis; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F | 1976 |
Inhibition of platelet aggregation by acetylsalicylic acid and other inhibitors.
Topics: Administration, Oral; Adult; Animals; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Indomethacin; Male; Platelet Aggregation; Rats; Time Factors | 1976 |
Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis.
Topics: Aspirin; Depression, Chemical; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Follow-Up Studies; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Prostaglandins | 1976 |
Vascular actions of furosemide and bumetanide on the rat superior mesenteric vascular bed: interactions with prolactin and prostaglandins.
Topics: Animals; Aspirin; Bumetanide; Diuretics; Drug Interactions; Furosemide; Indomethacin; Male; Mesentery; Prolactin; Prostaglandins E; Rats; Time Factors | 1976 |
Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse.
Topics: Animals; Aspirin; Body Weight; Cell Count; Histamine; Histidine Decarboxylase; Indomethacin; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Serotonin; Transplantation, Homologous | 1976 |
Effect of bases and accelerants on the anti-inflammatory activity of topical corticosteroids.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Drug Interactions; Guinea Pigs; Hydrocortisone; Indomethacin; Salicylates; Skin; Skinfold Thickness | 1976 |
The effect of indomethacin and other anti-inflammatory drugs on the renin-angiotensin system.
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Furosemide; Glomerular Filtration Rate; Indomethacin; Kidney; Meclofenamic Acid; Prostaglandins E; Rabbits; Renin | 1976 |
Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate.
Topics: Animals; Arachidonic Acids; Arteries; Aspirin; Cattle; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Humans; Indomethacin; Linolenic Acids; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Oleic Acids; Prostaglandins E; Prostaglandins F; Vasodilator Agents | 1976 |
Indomethacin inhibits responses to all vasoconstrictors in the rat mesenteric vascular bed: restoration of responses by prostaglandin E2.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Aspirin; Blood Pressure; Calcium; Drug Interactions; Histamine; Indomethacin; Male; Mefenamic Acid; Mesenteric Arteries; Muscle Contraction; Norepinephrine; Potassium; Prostaglandins E; Rats; Serotonin; Vasoconstrictor Agents | 1976 |
Acute respiratory failure secondary to indomethacin in an aspirin-intolerant asthmatic patient.
Topics: Acute Disease; Aspirin; Asthma; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged; Respiratory Insufficiency | 1976 |
Malondialdehyde production and the release reaction in rat blood platelets: inhibition by aspirin and indomethacin ex vivo [proceedings].
Topics: Animals; Aspirin; Blood Platelets; Depression, Chemical; Indomethacin; Malonates; Malondialdehyde; Rats; Serotonin; Time Factors | 1976 |
Medical management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Chloroquine; Gold; Humans; Ibuprofen; Indomethacin; Naproxen; Occupational Therapy; Phenylbutazone; Physical Therapy Modalities | 1976 |
Radioimmunoassay for urinary metabolites of prostaglandin F2alpha.
Topics: Animals; Aspirin; Estradiol; Estrus; Female; Guinea Pigs; Humans; Hysterectomy; Immune Sera; Immunization; Indomethacin; Injections, Intravenous; Male; Pregnancy; Prostaglandins F; Rabbits; Radioimmunoassay; Time Factors | 1976 |
The effect of thrombin on the uptake and transformation of arachidonic acid by human platelets.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipids; Thrombin | 1976 |
Corpus luteum function in the ewe: effect of PGF2alpha and prostaglandin synthetase inhibitors.
Topics: Acetates; Animals; Arachidonic Acids; Aspirin; Corpus Luteum; Dexamethasone; Estrus; Female; Flufenamic Acid; Indomethacin; Luteinizing Hormone; Pregnancy; Progesterone; Prostaglandins F; Sheep; Time Factors | 1976 |
Factor VIII and human platelet aggregation. II. Characteristics of aggregation of human platelets by bovine factor VIII.
Topics: Animals; Apyrase; Aspirin; Batroxobin; Blood Coagulation; Blood Platelets; Cattle; Factor VIII; Humans; Indomethacin; Oxidation-Reduction; Platelet Aggregation; Serotonin | 1976 |
Effects of inhibitors of prostaglandin synthesis on rebound excitation of guinea-pig small bowel.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Indomethacin; Jejunum; Male; Muscle Contraction; Neurons; Prostaglandins | 1976 |
Antagonism of arachidonic acid-induced bronchoconstriction in cats by aspirin-like analgesics.
Topics: Acetaminophen; Analgesics; Animals; Arachidonic Acids; Aspirin; Bronchi; Cats; Female; Flufenamic Acid; Indomethacin; Male; Phenylbutazone | 1976 |
Anti-ulcer effects of 4'-(2-carboxyetyl) phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Cortisone; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Glucuronidase; Indomethacin; Phenylbutazone; Pylorus; Rats; Stomach Ulcer | 1976 |
Failure of indomethacin to reduce hypercalcemia in patients with breast cancer.
Topics: Aspirin; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Humans; Hydroxyproline; Hypercalcemia; Indomethacin; Neoplasm Metastasis; Parathyroid Hormone; Phosphates | 1976 |
The effect of reported prostaglandin synthetase inhibitors on estradiol-stimulated uterine prostaglandin biosynthesis in vivo in the ovariectomized rat.
Topics: Animals; Aspirin; Dronabinol; Estradiol; Female; Indomethacin; Naproxen; Organ Size; Ovary; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rats; Time Factors; Uterus | 1976 |
[Gastrointestinal hemorrhage caused by side effect of drugs].
Topics: Adult; Aged; Aspirin; Butadienes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Indomethacin; Male; Middle Aged; Peptic Ulcer; Peptic Ulcer Hemorrhage; Prednisolone; Reserpine | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans | 1976 |
Some pharmacological and toxicological studies on ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indomethacin; Inflammation; Ketoprofen; Mice; Pain; Rabbits; Rats | 1976 |
Improved survival in endotoxemia with aspirin and indomethacin pretreatment.
Topics: Animals; Aspirin; Dogs; Endotoxins; Hemodynamics; Indomethacin; Male; Shock, Septic | 1976 |
Prostaglandin E2 prevents aspirin and indomethacin damage to human gastric mucosa.
Topics: Adult; Aspirin; Gastric Mucosa; Humans; Indomethacin; Male; Prostaglandins E | 1976 |
[Various problems of drug treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Butadienes; Drug Evaluation; Humans; Ibuprofen; Indomethacin | 1976 |
Inhibiting effect of feprazone on "in vitro" human platelet aggregation.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Collagen; Humans; In Vitro Techniques; Indomethacin; Phenylbutazone; Platelet Aggregation; Salicylates | 1976 |
The effect of low concentrations of prostaglandin E1 on myoblast fusion.
Topics: Animals; Aspirin; Cell Differentiation; Cell Fusion; Chick Embryo; Indomethacin; Muscles; Prostaglandins E; Time Factors | 1976 |
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship | 1975 |
Salicylate therapy and drug interaction in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Salicylates | 1975 |
Drug interactions in the management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Phenylbutazone; Prednisolone; Protein Binding; Salicylates | 1976 |
[Letter: Antirheumatics].
Topics: Aspirin; Humans; Indomethacin; Phenylbutazone; Rheumatic Diseases | 1975 |
Sensible prescribing. The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthroplasty; Aspirin; Cryotherapy; Exercise Therapy; Humans; Hydrostatic Pressure; Immunosuppressive Agents; Indomethacin; Injections, Intra-Articular; Ketoprofen; Methylprednisolone; Oxyphenbutazone; Penicillamine; Phenylbutazone; Pressure | 1975 |
[Effect of anti-inflammatory preparations on the process of thermogenesis in blood erythrocytes].
Topics: Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chloroquine; Depression, Chemical; Energy Metabolism; Erythrocytes; Glycolysis; Humans; Indomethacin; Phenylbutazone; Prednisolone | 1975 |
Inflammatory disease and its control in rheumatic disorders.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Female; Gout; Humans; Indomethacin; Inflammation; Male; Middle Aged; Oxyphenbutazone; Phenylbutazone; Polymyalgia Rheumatica; Rheumatic Diseases; Spondylitis, Ankylosing | 1975 |
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Capillary Permeability; Codeine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythema; Female; Fever; Flurbiprofen; Guinea Pigs; Indomethacin; Inflammation; Liver Glycogen; Male; Mice; Phenylbutazone; Propionates; Rats; Spasm | 1975 |
Medical management of rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Aspirin; Cyclophosphamide; Exercise Therapy; Glucocorticoids; Gold; Humans; Indomethacin; Muscular Atrophy; Phenacetin; Phenylbutazone | 1976 |
The anti-inflammatory agents used in rheumatic disorders.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Anti-Inflammatory Agents; Antimalarials; Aspirin; Colchicine; Gold; Humans; Indomethacin; Phenylbutazone; Rheumatic Diseases; Salicylates | 1975 |
Drug-associated deaths of medical inpatients.
Topics: Adolescent; Adult; Aged; Aspirin; Azathioprine; Drug Therapy; Female; Florida; Gastrointestinal Hemorrhage; Heparin; Humans; Indomethacin; Male; Middle Aged; Prednisone | 1976 |
The anti-inflammatory and analgesic effects of norvedan a novel, non-steroidal agent.
Topics: Acetates; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Female; Indomethacin; Male; Mice; Phenylbutazone; Rats; Spasm; Thiazoles; Time Factors | 1976 |
Rheumatic diseases. 2. Therapeutic considerations.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Calcinosis; Carpal Tunnel Syndrome; Colchicine; Gout; Hip Joint; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Osteoarthritis; Phenylbutazone; Rheumatic Diseases; Spondylitis, Ankylosing; Tendinopathy | 1976 |
Gastric damage by drugs and the role of the mucosal barrier.
Topics: Animals; Aspirin; Dogs; Ethanol; Gastric Mucins; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Indomethacin; Prednisone; Sodium; Stomach Ulcer | 1976 |
[Experimental studies on the possibility of influencing mast cells in experimental carrageenin-induced rat paw edema. Histological study on the effects of some non-steroidal anti-inflammatory agents (author's transl)].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Cell Count; Edema; Indomethacin; Male; Mast Cells; Phenylbutazone; Rats | 1976 |
Bone and joint diseases in the elderly.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Age Factors; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Counseling; Diagnosis, Differential; Female; Gold; Gout; Humans; Hydroxychloroquine; Immunosuppressive Agents; Indomethacin; Male; Osteoarthritis; Osteoporosis; Penicillamine; Polymyalgia Rheumatica; Rheumatic Diseases | 1976 |
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; Humans; In Vitro Techniques; Indomethacin; Male; Mefenamic Acid; Microsomes; Middle Aged; Mixed Function Oxygenases; Nasal Polyps; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pulse; Rhinitis; Spirometry | 1975 |
Effect of the administration of antirheumatic drugs on experimental granuloma in rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cellulose; Cytidine; Granuloma; Hexosamines; Hydroxyproline; Indomethacin; Male; Nitrogen; Nucleic Acids; Phenylbutazone; Prednisolone; Proline; Rats; Sulfates; Uronic Acids | 1975 |
Letter: Aspirin sensitivity: other drugs.
Topics: Adult; Analgesics; Angioedema; Aspirin; Depression, Chemical; Drug Hypersensitivity; Female; Humans; Indomethacin; Male; Placebos; Prostaglandins; Urticaria | 1975 |
Endotoxin-induced prostaglandin E and F release in dogs.
Topics: Animals; Aorta; Aspirin; Blood Pressure; Cardiac Output; Dogs; Indomethacin; Portal Vein; Prostaglandins; Renal Veins; Shock, Septic; Time Factors; Venous Pressure | 1975 |
Effect of diftalone and other nonsteroidal anti-inflammatory agents on synthesis of prostaglandins (38560).
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Binding, Competitive; Cattle; Depression, Chemical; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; Microsomes; Phenylbutazone; Phthalazines; Prostaglandins; Pyridazines; Seminal Vesicles | 1975 |
A sensitive method for the comparative bioassay of nonsteroidal anti-inflammatory compounds in adjuvant-induced primary inflammation in the rat.
Topics: Aminopyrine; Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biological Assay; Disease Models, Animal; Dose-Response Relationship, Drug; Flufenamic Acid; Freund's Adjuvant; Indomethacin; Male; Mefenamic Acid; Phenylbutazone; Rats; Time Factors | 1975 |
The effect of drugs on implantation in rats with an intrauterine device in one horn of the uterus.
Topics: Administration, Oral; Animals; Aspirin; Copulation; Embryo Implantation; Fallopian Tubes; Female; Indomethacin; Injections, Intramuscular; Injections, Subcutaneous; Intrauterine Devices; Luteinizing Hormone; Male; Pregnancy; Progesterone; Prolactin; Prostaglandins; Rats | 1975 |
Prostaglandins, antipyretic analgesics and adrenergic stimuli on the isolated artery.
Topics: 8,11,14-Eicosatrienoic Acid; Analgesics; Animals; Arachidonic Acids; Arteries; Aspirin; Cocaine; Electric Stimulation; In Vitro Techniques; Indomethacin; Norepinephrine; Prostaglandins; Rabbits; Sympathetic Nervous System | 1975 |
Inhibition by aspirin and indomethacin of uterine hypertrophy induced by an IUD.
Topics: Animals; Aspirin; Castration; Fallopian Tubes; Female; Hydrocortisone; Hypertrophy; Indomethacin; Intrauterine Devices; Meclofenamic Acid; Organ Size; Ovary; Rats; Sutures; Uterine Diseases; Uterus | 1975 |
The aging skeleton. Osteoporosis and degenerative arthritis.
Topics: Age Factors; Aged; Aspirin; Estrogens; Female; Fracture Fixation; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Male; Osteoarthritis; Osteoporosis; Phenylbutazone; Sex Factors | 1975 |
Ocular compression and noncorticosteroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Conjunctiva; Eye Diseases; Humans; Hyperemia; Indomethacin; Injections, Intraperitoneal; Intraocular Pressure; Iris; Male; Pressure; Rabbits; Tonometry, Ocular | 1975 |
Mechanisms of concanavalin A-induced inflammation in the rat.
Topics: Animals; Aspirin; Concanavalin A; Indomethacin; Inflammation; Kinins; Male; Prostaglandins; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1975 |
Influence of prostaglandins E1, E2, and arachidonate on melanosomes in melanocytes and keratinocytes of anagen hair bulbs in vitro.
Topics: Arachidonic Acids; Aspirin; Caproates; Hair; Humans; Indomethacin; Keratins; Melanocytes; Organ Culture Techniques; Organoids; Prostaglandins E; Stearic Acids | 1975 |
The effect of a new anti-inflammatory agent, the ethoxy methyl ester of N-(2,6-dichloro-m-tolyl)-anthranilic acid (A3), on platelet behaviour "in vivo" and "in vitro".
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arterial Occlusive Diseases; Aspirin; Blood Coagulation; Blood Platelets; Dose-Response Relationship, Drug; Drug Evaluation; Ethyl Ethers; Female; In Vitro Techniques; Indomethacin; Male; Mice; ortho-Aminobenzoates; Phenylbutazone; Platelet Aggregation; Prothrombin Time; Rabbits; Rats; Thrombin; Thrombosis; Toluene | 1975 |
Choice of drugs in rheumatoid arthritis in adults.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Costs and Cost Analysis; Humans; Indomethacin | 1975 |
Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint.
Topics: Analgesia; Animals; Aspirin; Blood Pressure; Bradykinin; Carrageenan; Depression, Chemical; Dogs; Female; Indomethacin; Inflammation; Knee Joint; Lidocaine; Male; Prostaglandins; Prostaglandins E; Reflex | 1975 |
Systemic aspirin and indomethacin do not prevent the response of the monkey eye to trauma.
Topics: Animals; Aqueous Humor; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Endotoxins; Eye Injuries; Eye Proteins; Indomethacin; Intraocular Pressure; Macaca mulatta; Punctures; Shigella; Uveitis | 1975 |
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Myometrium; Phenylbutazone; Pregnancy; Pregnancy Trimester, Second; Prostaglandin Antagonists; Prostaglandins F; Rabbits; Stimulation, Chemical; Uterine Contraction; Uterus | 1975 |
Action of the anti-inflammatory agents, acetylsalicylic acid, indomethacin and fenoprofen on the gastric mucosa of dogs.
Topics: Animals; Aspirin; Calcium; Dogs; Fenoprofen; Gastric Acidity Determination; Gastric Mucosa; Indomethacin; Magnesium; Phenylpropionates; Potassium; Sodium; Time Factors | 1975 |
Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets.
Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth; Perfusion; Peroxides; Platelet Aggregation; Prostaglandins; Rabbits; Stimulation, Chemical; Thrombin | 1975 |
Increase of experimental hypertension following inhibition of prostaglandin biosynthesis.
Topics: Angiotensin II; Animals; Aspirin; Depression, Chemical; Hypertension, Renal; Indomethacin; Male; Mefenamic Acid; Prostaglandins; Rats; Renin | 1975 |
Letter: Indomethacin-aspirin interactions.
Topics: Aspirin; Drug Interactions; Humans; Indomethacin | 1975 |
Contractile responses of the guinea-pig trachea in vitro: modification by prostaglandin synthesis-inhibiting drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Anti-Inflammatory Agents; Aspirin; Barium; Depression, Chemical; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Potassium; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Salicylates; Serotonin; Trachea | 1975 |
Acute pulmonary edema and plasma kininogen consumption in the adrenaline-treated rat: inhibition by acetylsalicylic acid and resistance to salicylate and indomethacin.
Topics: Animals; Aspirin; Drug Resistance; Epinephrine; Indomethacin; Kininogens; Male; Pulmonary Edema; Rats; Salicylates | 1975 |
Effect of prostaglandin E2 on the pressor response to periarterial stimulation and norepinephrine of the isolated perfused rabbit kidney.
Topics: Animals; Aorta; Aspirin; Depression, Chemical; Drug Interactions; Electric Stimulation; Female; Indomethacin; Kidney; Ligation; Male; Muscle Contraction; Norepinephrine; Perfusion; Pressure; Prostaglandins E; Rabbits; Renal Artery; Stimulation, Chemical | 1975 |
Floctafenine, a new non-narcotic analgesic.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dextropropoxyphene; Dogs; Edema; Erythema; Female; Guinea Pigs; Indomethacin; Male; Mice; ortho-Aminobenzoates; Quinolines; Rats; Reaction Time; Stomach Ulcer | 1975 |
[Gastric ulcer induced in the rat by non-steroid anti-inflammatory agents and the synergic effect of exogenous histamine].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Synergism; Flufenamic Acid; Histamine; Indomethacin; Phenylbutazone; Rats; Stomach Ulcer | 1975 |
Chemistry and pharmacology of naproxen.
Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Fever; Granuloma; Indomethacin; Male; Mice; Naphthaleneacetic Acids; Naproxen; Phenylbutazone; Pressure; Quinones; Rats; Yeast, Dried | 1975 |
Biological properties of a new non-steroidal anti-inflammatory drug: etoclofene.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Edema; Female; Guinea Pigs; Indomethacin; Lethal Dose 50; Male; Meclofenamic Acid; Mefenamic Acid; Mice; ortho-Aminobenzoates; Phenylbutazone; Rats | 1975 |
The pulmonary vasoconstrictor response to hypoxia: effects of inhibitors of prostaglandin biosynthesis.
Topics: Animals; Aspirin; Blood Pressure; Depression, Chemical; Hypoxia; Indomethacin; Meclofenamic Acid; ortho-Aminobenzoates; Prostaglandins; Pulmonary Artery; Pulmonary Circulation; Pulmonary Veins; Rats; Stimulation, Chemical; Vascular Resistance | 1975 |
Meiosis: a prostaglandin response that is not inhibited by aspirin.
Topics: Animals; Aspirin; Electric Stimulation; Indomethacin; Miotics; Prostaglandins; Pupil; Rabbits; Time Factors | 1975 |
Effect of anti-inflammatory agents on accelerated granuloma formation in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Flufenamic Acid; Granuloma; Indomethacin; Male; Phenylbutazone; Prednisolone; Rats | 1975 |
Proceedings: Antidromic dilatation in skeletal muscle.
Topics: Animals; Aspirin; Cats; Dilatation; Evoked Potentials; Indomethacin; Muscles; Neurons; Neurons, Afferent; Spinal Nerve Roots | 1975 |
Prostaglandins as mediators of hypercalcemia associated with certain types of cancer.
Topics: Aspirin; Calcium; Humans; Hypercalcemia; Indomethacin; Male; Middle Aged; Neoplasms; Parathyroid Hormone; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E | 1975 |
Editorial: Prostaglandins, hypercalcemia and cancer.
Topics: Animals; Aspirin; Humans; Hypercalcemia; Indomethacin; Mice; Neoplasms; Prostaglandin Antagonists; Prostaglandins; Rabbits | 1975 |
Depression of taste responses by local or intravascular administration of salicylates in the rat.
Topics: Administration, Topical; Animals; Aspirin; Depression, Chemical; Indomethacin; Injections, Intra-Arterial; Injections, Intravenous; Male; Rats; Sodium Chloride; Sodium Salicylate; Taste Buds | 1975 |
Characteristic features of actinomycin D-induced paw inflammation of the rat.
Topics: Acid Phosphatase; Animals; Aspirin; Capillary Permeability; Dactinomycin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extremities; Glucuronidase; Histamine; Hydrocortisone; Indomethacin; Inflammation; Male; Rats | 1975 |
A high-speed liquid chromatographic analysis of indomethacin in plasma.
Topics: Aspirin; Chromatography, High Pressure Liquid; Flufenamic Acid; Furosemide; Indomethacin | 1975 |
Lipid A fever in cats.
Topics: Acetaminophen; Animals; Aspirin; Body Temperature; Cats; Female; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Lipids; Lipopolysaccharides; Male; Prostaglandins E; Salmonella | 1975 |
The effects of HCG, indomethacin, flufenamic acid and aspirin in the immature female rat.
Topics: Animals; Aspirin; Chorionic Gonadotropin; Female; Flufenamic Acid; Indomethacin; Organ Size; Ovary; Proteins; Rats; Uterus | 1975 |
[Advances in pneumonology. Aspirin-induced asthma].
Topics: Adult; Age Factors; Aspirin; Asthma; Depression, Chemical; Drug Hypersensitivity; Humans; Indomethacin; Middle Aged; Prostaglandins; Syndrome | 1975 |
Effects of pretreatment with anti-inflammatory drugs on ozone-induced lung damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Heparin; Hydrocortisone; Indomethacin; Male; Ozone; Prostaglandins; Pulmonary Edema; Rats | 1975 |
[Evaluation of the effectiveness of antirheumatic preparations].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Joints; Male; Meprobamate; Methods; Middle Aged; Prednisolone; Sodium Salicylate | 1975 |
[Proceedings: Case of acute idiopathic recurring pericarditis].
Topics: Acute Disease; Aspirin; Child; Cortisone; Humans; Indomethacin; Male; Pericarditis; Recurrence | 1975 |
The effect of buffered aspirin on plasma indomethacin.
Topics: Adult; Aspirin; Biological Availability; Blood Proteins; Buffers; Capsules; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Male; Protein Binding; Solubility; Tablets; Time Factors | 1975 |
Interaction of indomethacin and acetylsalicylic acid as shown by the serum concentrations of indomethacin and salicylate.
Topics: Administration, Oral; Adult; Aged; Aspirin; Drug Interactions; Female; Half-Life; Humans; Indomethacin; Male; Middle Aged; Salicylates; Suppositories | 1975 |
[Follow-up of the treatment of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Female; Follow-Up Studies; Gold; Gold Radioisotopes; Humans; Indomethacin; Male | 1975 |
Suprofen, a potent antagonist of acetic acid-induced writhing in rats.
Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indomethacin; Ketoprofen; Male; Muscle Contraction; Phenylacetates; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Rats; Spasm; Thiophenes; Tolmetin | 1975 |
Suprofen, a potent antagonist of sodium urate crystal-induced arthritis in dogs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indomethacin; Knee Joint; Male; Phenylbutazone; Phenylpropionates; Thiophenes; Time Factors; Uric Acid | 1975 |
The activity of suprofen on nystatin-induced paw oedema in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Hindlimb; Indomethacin; Male; Nystatin; Phenylbutazone; Phenylpropionates; Rats; Thiophenes; Time Factors | 1975 |
The antipyretic effect of suprofen in rats with yeast-induced fever.
Topics: Analgesics; Animals; Aspirin; Body Temperature; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fever; Indomethacin; Male; Phenylbutazone; Phenylpropionates; Rats; Thiophenes; Time Factors; Tolmetin; Yeast, Dried | 1975 |
The effects of suprofen in rats with Mycobacterium butyricum-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biometry; Body Weight; Bone and Bones; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Haptoglobins; Hindlimb; Indomethacin; Phenylbutazone; Phenylpropionates; Rats; Tarsal Joints; Thiophenes; Tolmetin | 1975 |
Gastrointestinal effects and acute toxicity of suprofen.
Topics: Animals; Antidiarrheals; Aspirin; Digestive System; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eating; Female; Guinea Pigs; Indomethacin; Ketoprofen; Lethal Dose 50; Male; Mice; Phenylacetates; Phenylpropionates; Rats; Rats, Inbred Strains; Thiophenes; Time Factors; Ulcer | 1975 |
Prostaglandin E1 high affinity binding sites of rat thymocytes. Specificity and blockade by non-steroidal antiinflammatory drugs and localization in a plasma membrane-enriched fraction.
Topics: Animals; Aspirin; Binding Sites; Binding, Competitive; Cell Membrane; Female; In Vitro Techniques; Indomethacin; Kinetics; L-Lactate Dehydrogenase; Nucleotidases; Prostaglandins E; Prostaglandins E, Synthetic; Protein Binding; Rats; Salicylates; Structure-Activity Relationship; Thymus Gland | 1976 |
Reptilase clot retraction induced by electrical stimulation.
Topics: Apyrase; Aspirin; Batroxobin; Blood Platelets; Calcium; Clot Retraction; Electric Stimulation; Humans; Indomethacin; Magnesium; Peptide Hydrolases; Potassium; Prostaglandins E; Pyruvate Kinase; Time Factors; Xanthines | 1976 |
[Methoxypropriocin in the treatment of degenerative bone disease (comparative studies)].
Topics: Aspirin; Benzydamine; Chronic Disease; Humans; Indomethacin; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Spondylitis, Ankylosing | 1976 |
Endogenous prostaglandin in guinea pig taenia coli.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Animals; Aspirin; Atropine; Carbachol; Colon; Dose-Response Relationship, Drug; Ethanol; Guinea Pigs; Indomethacin; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ouabain; Phenoxybenzamine; Phentolamine; Potassium; Propranolol; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Scopolamine | 1976 |
The influence of aspirin and indomethacin on the platelet contractile wave.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation; Prostaglandins; Thrombin | 1976 |
Synthesis of platelet-aggregating factor by human platelet microsomes.
Topics: Aspirin; Blood Coagulation Factors; Blood Platelets; Drug Stability; Fenoprofen; Humans; Indomethacin; Microsomes; Platelet Aggregation; Time Factors | 1976 |
Drugs and gastric damage.
Topics: Adrenal Cortex Hormones; Aspirin; Buffers; Caffeine; Drug Compounding; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; Indomethacin; Phenylbutazone; Reserpine; Smoking; Stomach Diseases; Stomach Ulcer | 1976 |
Samuel Hyde lecture. Polypharmacy in rheumatoid arthritis--help or hindrance?
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Protein Binding; Serum Albumin | 1976 |
Pulmonary damage following pulmonary microembolism in the dog. Effect of various types of treatment.
Topics: Animals; Aspirin; Calcium; Cyclohexanecarboxylic Acids; Dogs; Female; Indomethacin; Lung; Male; Methylprednisolone; Methysergide; Microcirculation; Phenoxybenzamine; Polyphloretin Phosphate; Pulmonary Edema; Pulmonary Embolism; Pyrilamine; Reserpine; Thrombin; Tranexamic Acid; Vascular Resistance | 1976 |
Inhibition of prostaglandin biosynthesis by SL-573.
Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Depression, Chemical; In Vitro Techniques; Indomethacin; Kinetics; Male; Microsomes; Prostaglandins; Prostaglandins E; Quinazolines; Quinazolinones; Seminal Vesicles | 1976 |
Inhibition of platelet aggregation by papaverine-like drugs: evidence for a novel mechanism of action.
Topics: Adenosine Diphosphate; Aspirin; Collagen; Epinephrine; Humans; Indomethacin; Isoproterenol; Papaverine; Phentolamine; Platelet Aggregation; Practolol; Propranolol; Tretoquinol | 1976 |
Editorial: Pain relief in minor musculoskeletal disorders.
Topics: Aspirin; Athletic Injuries; Dimethyl Sulfoxide; Humans; Indomethacin; Pain; Sprains and Strains | 1976 |
Adult-onset Still's disease.
Topics: Adult; Age Factors; Arthritis, Juvenile; Aspirin; Humans; Indomethacin; Prednisone | 1976 |
Pharmacological modulation of the endotoxin-induced increase in plasminogen activator inhibitor activity in rats.
Topics: 1-Methyl-3-isobutylxanthine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Dose-Response Relationship, Drug; Enzyme Activation; Indomethacin; Lipopolysaccharides; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar; Tissue Plasminogen Activator | 1992 |
Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo.
Topics: Animals; Aspirin; Dinoprostone; Ethanol; Ethylmaleimide; Gastric Mucins; Gastric Mucosa; Image Processing, Computer-Assisted; Indomethacin; Microscopy, Electron, Scanning; Necrosis; Ornithine Decarboxylase; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases; Tyrosine | 1992 |
Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: I. Nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Female; Humans; Indomethacin; Ketoprofen; Long-Term Care; Male; Meclofenamic Acid; Middle Aged; Private Practice; Surveys and Questionnaires | 1992 |
Comparison of the anti-inflammatory effects of topically applied aspirin and indomethacin following photocoagulation of the rabbit iris.
Topics: Administration, Topical; Animals; Aspirin; Indomethacin; Iris; Light Coagulation; Rabbits; Time Factors | 1992 |
Chemical modification of prostaglandin H synthase with diethyl pyrocarbonate.
Topics: Acetylation; Animals; Apoenzymes; Aspirin; Cyclooxygenase Inhibitors; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Glucosides; Histidine; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Male; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Sheep; Spectrophotometry; Structure-Activity Relationship | 1992 |
Disturbed lipid metabolism in diabetic coronary vessels.
Topics: Alloxan; Animals; Arachidonic Acids; Aspirin; Coronary Circulation; Coronary Vessels; Diabetes Mellitus, Experimental; Dogs; Epoprostenol; Female; Indomethacin; Male; Microcirculation; Myocardium; Norepinephrine; Phentolamine; Prazosin; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, alpha; Thromboxane A2; Vasoconstriction | 1992 |
The role of prostaglandin H synthase in 3-methylindole-induced pneumotoxicity in goat.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Goat Diseases; Goats; Indomethacin; Lung Diseases; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Skatole | 1992 |
Effect of aspirin and indomethacin on epidermal growth factor secretion in duodenal tissue fragments cultivated in vitro.
Topics: Adult; Aspirin; Cells, Cultured; Duodenum; Epidermal Growth Factor; Female; Humans; Indomethacin; Male; Middle Aged; Radioimmunoassay; Somatostatin | 1992 |
Influences of cyclooxygenase inhibitors on the cataleptic behavior induced by haloperidol in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspirin; Catalepsy; Corpus Striatum; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dopamine; Drug Interactions; Haloperidol; Hydroxyindoleacetic Acid; Indomethacin; Male; Mice; Neurotransmitter Agents; Prostaglandins; Serotonin; Tromethamine | 1992 |
Ultraviolet B dose-dependent inflammation in humans: a reflectance spectroscopic and laser Doppler flowmetric study using topical pharmacologic antagonists on irradiated skin.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Diphenhydramine; Dose-Response Relationship, Radiation; Erythema; Female; Humans; Indomethacin; Laser-Doppler Flowmetry; Middle Aged; Skin; Spectrometry, Fluorescence; Ultraviolet Rays | 1992 |
Effect of aspirin, flurbiprofen and indomethacin on porcine testicular steroidogenesis.
Topics: Animals; Aspirin; Chromatography, Gas; Flurbiprofen; Indomethacin; Male; Microsomes; Steroids; Swine; Testis; Testosterone | 1992 |
Some properties of purified Escherichia coli heat-stable enterotoxin II.
Topics: Animals; Aspirin; Bacterial Toxins; Biological Assay; Cholera Toxin; Diarrhea; Dinoprostone; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Indomethacin; Mice; Nucleotides, Cyclic; Protease Inhibitors; Time Factors | 1992 |
Potentiation by cyclooxygenase inhibitors of the release of catecholamines from the rabbit carotid body and its reversal by prostaglandin E2.
Topics: Animals; Aspirin; Carotid Body; Catecholamines; Cyclooxygenase Inhibitors; Dinoprostone; In Vitro Techniques; Indomethacin; Kinetics; Rabbits | 1992 |
Antithrombotic activity of a new pyrazine derivative determined by the mouse antithrombotic assay.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Embolization, Therapeutic; Fibrinolytic Agents; Humans; Indomethacin; Lung; Male; Mice; Platelet Aggregation; Pyrazines | 1992 |
Lack of prostaglandin effect on sodium balance and hyperreninemia in adrenalectomized rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Aspirin; Dexamethasone; Dinoprostone; Epoprostenol; Homeostasis; Indomethacin; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Renin; Sodium | 1992 |
Low concentrations of lithium and cyclooxygenase inhibitors enhance endothelin-1 (ET-1)-induced contractions in human temporal artery, but not in porcine ophthalmic artery.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelins; Humans; Indomethacin; Lithium; Naproxen; Ophthalmic Artery; Osmolar Concentration; Swine; Temporal Arteries; Vasoconstriction | 1992 |
Chemotaxis of human blood monocytes toward endothelin-1 and the influence of calcium channel blockers.
Topics: Aspirin; Calcium Channel Blockers; Chemotaxis, Leukocyte; Diltiazem; Dose-Response Relationship, Drug; Endothelins; Humans; In Vitro Techniques; Indomethacin; Kinetics; Monocytes; Neomycin; Nifedipine; Probucol; Thioctic Acid; Verapamil | 1992 |
Prostanoids modulate opioid-induced increases in cerebrospinal fluid vasopressin concentration.
Topics: Animals; Animals, Newborn; Arterioles; Aspirin; Endorphins; Female; Indomethacin; Male; Osmolar Concentration; Pia Mater; Prostaglandins; Swine; Vasodilation; Vasopressins | 1992 |
Role of prostaglandins in the testosterone-dependent wolffian duct differentiation of the fetal mouse.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Cell Differentiation; Cortisone; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Hydrocortisone; Indomethacin; Mice; Organ Culture Techniques; Testosterone; Wolffian Ducts | 1992 |
Nonessential role of leukotrienes as mediators of acute gastric mucosal injury induced by aspirin in rats.
Topics: Acute Disease; Animals; Aspirin; Gastric Mucosa; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Male; Propionates; Quinolines; Rats; Rats, Inbred Strains; Sodium Salicylate; SRS-A | 1992 |
Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 cases (1989-1990)
Topics: Accidents; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cat Diseases; Cats; Dog Diseases; Dogs; Gastrointestinal Diseases; Ibuprofen; Indomethacin; Poisoning; Retrospective Studies | 1992 |
Taurine potentiates the antiaggregatory action of aspirin and indomethacin.
Topics: Adult; Aspirin; Drug Synergism; Humans; Indomethacin; L-Lactate Dehydrogenase; Malondialdehyde; Middle Aged; Platelet Aggregation Inhibitors; Taurine | 1992 |
Dirofilaria immitis: do filarial cyclooxygenase products depress endothelium-dependent relaxation in the in vitro rat aorta?
Topics: Acetylcholine; Animals; Aorta, Thoracic; Aspirin; Dirofilaria immitis; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Prostaglandin D2; Rats; Rats, Inbred Strains; Vasodilation | 1992 |
Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Bone Matrix; Flurbiprofen; Indomethacin; Male; Osteogenesis; Piroxicam; Rats | 1992 |
Blunted hypoxic vasoconstriction in oleic acid lung injury: effect of cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Hypoxia; Indomethacin; Lung; Lung Injury; Oleic Acid; Oleic Acids; Pulmonary Circulation; Pulmonary Edema; Pulmonary Gas Exchange; Vasoconstriction | 1992 |
Cyclooxygenase inhibition aggravates pulmonary hypertension and deteriorates gas exchange in canine pulmonary embolism.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dogs; Hypertension, Pulmonary; Indomethacin; Pulmonary Circulation; Pulmonary Embolism; Pulmonary Gas Exchange | 1992 |
Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Humans; Hypoxia; In Vitro Techniques; Indomethacin; Isometric Contraction; Macaca; Male; Methacrylates; Muscle Relaxation; Muscle, Smooth, Vascular; Papaverine; Prostaglandins; Species Specificity; Superoxide Dismutase; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1992 |
Effects of indomethacin, aspirin, and acetaminophen on ethanol diuresis in rats.
Topics: Acetaminophen; Alcohol Drinking; Animals; Aspirin; Diuresis; Dose-Response Relationship, Drug; Female; Indomethacin; Prostaglandins; Rats; Rats, Inbred Strains | 1992 |
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Ethanol; Furans; Indomethacin; Male; Molecular Structure; Rats; Rats, Inbred Strains; Stomach Ulcer; Structure-Activity Relationship | 1992 |
Ionic, electrical, and secretory effects of inhibitors of arachidonic acid metabolism in mouse pancreatic beta-cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Aspirin; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Conductivity; Female; Glucose; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Insulin; Islets of Langerhans; Lipoxygenase Inhibitors; Membrane Potentials; Mice; Microelectrodes; Potassium; Potassium Channels; Radioimmunoassay; Rubidium Radioisotopes; Sodium Salicylate | 1992 |
Effects of butylated hydroxyanisole on arachidonic acid and linoleic acid metabolism in relation to gastrointestinal cell proliferation in the rat.
Topics: Animals; Arachidonic Acid; Aspirin; Butylated Hydroxyanisole; Cell Division; Digestive System; Indomethacin; Linoleic Acid; Linoleic Acids; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1992 |
Effects of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on platelet aggregation and thrombosis in experimental animals.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Bridged Bicyclo Compounds; Cyclooxygenase Inhibitors; Dogs; Electroencephalography; Female; Fibrinolytic Agents; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred ICR; Nicotinic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred Strains; Respiration; Stomach Ulcer | 1992 |
L-NMMA in brain microcirculation of mice is inhibited by blockade of cyclooxygenase and by superoxide dismutase.
Topics: Animals; Arginine; Aspirin; Blood Platelets; Cell Adhesion; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Free Radical Scavengers; Indomethacin; Male; Mice; Mice, Inbred ICR; Microcirculation; Nitroarginine; omega-N-Methylarginine; Platelet Aggregation; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1992 |
Short-term treatment with nonsteroidal antiinflammatory medications to prevent heterotopic bone formation after total hip arthroplasty. A preliminary report.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Hip Prosthesis; Humans; Indomethacin; Male; Middle Aged; Ossification, Heterotopic; Postoperative Complications; Radiography | 1992 |
Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fibre-evoked activity in the rat thalamus and spinal cord.
Topics: Afferent Pathways; Animals; Aspirin; Axons; Behavior, Animal; Female; Indomethacin; Injections, Spinal; Male; Nerve Fibers; Neurons; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Spinal Cord; Thalamus | 1992 |
An 1,2,3-triazole derivative bioisoster of a potent in vitro prostaglandin synthesis inhibitor: preparation and biological activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Indomethacin; Malondialdehyde; Prostaglandin Antagonists; Triazoles | 1992 |
Ibuprofen, indomethacin, and high-dose aspirin, but not low-dose aspirin or imidazole, inhibit CGRP elevations in plasma during endotoxicosis.
Topics: Animals; Aspirin; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endotoxins; Ibuprofen; Imidazoles; Indomethacin; Rats; Reference Values; Salmonella enteritidis; Shock, Septic | 1992 |
Up-regulation of thrombomodulin by activation of histamine H1-receptors in human umbilical-vein endothelial cells in vitro.
Topics: Antigens; Aspirin; Cells, Cultured; Endothelium, Vascular; Histamine; Humans; Indomethacin; Kinetics; Protein C; Receptors, Cell Surface; Receptors, Histamine H1; Receptors, Thrombin; RNA, Messenger; Umbilical Veins; Up-Regulation | 1991 |
The prostaglandin paradox: additive inhibition of neutrophil function by aspirin-like drugs and the prostaglandin E1 analog misoprostol.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Calcium; Cell Aggregation; Cyclic AMP; Depression, Chemical; Drug Synergism; Glucuronidase; Humans; Indomethacin; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins; Sodium Salicylate; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Regional effects of indomethacin, acetylsalicylic acid and SC-19220 on the contractility of rabbit renal pelvis (pacemaker regions and pelviureteric junction).
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Electric Stimulation; In Vitro Techniques; Indomethacin; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Tetrodotoxin; Ureter | 1991 |
Effect of calcium concentration and inhibitors on the responses of platelets stimulated with collagen: contrast between human and rabbit platelets.
Topics: Animals; Aspirin; Blood Platelets; Calcium; Cell Degranulation; Collagen; Cyclooxygenase Inhibitors; Cytosol; Humans; In Vitro Techniques; Indomethacin; Ketanserin; Kinetics; Rabbits; Thromboxane A2 | 1991 |
[The part of lysosomal enzymes in drug-induced ulcerogenesis].
Topics: Animals; Aspirin; Cathepsins; Deoxyribonucleases; Indomethacin; Lysosomes; Male; Phenylbutazone; Quinolines; Rats; Rats, Inbred Strains; Ribonucleases; Stomach; Stomach Ulcer | 1991 |
Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Histamine H1 Antagonists; Indomethacin; Male; Mast Cells; Quinolines; Ranitidine; Rats; Rats, Inbred Strains; Stomach Ulcer | 1991 |
Influence of short-chain fatty acids on vascular tone.
Topics: Animals; Aspirin; Blood Pressure; Cats; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprost; Dose-Response Relationship, Drug; Fatty Acids, Volatile; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits | 1991 |
Different effects of prostaglandins on adrenergic neurotransmission in atrial and ventricular preparations.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Electric Stimulation; Epoprostenol; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Iloprost; In Vitro Techniques; Indomethacin; Injections, Intraventricular; Prostaglandins; Sympathetic Nervous System; Synaptic Transmission | 1990 |
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma.
Topics: Adult; Aged; Aspirin; Asthma; Basophils; Cytochalasin B; Dexamethasone; Female; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Male; Middle Aged; Platelet Activating Factor | 1990 |
Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Aspirin; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cycloheximide; Epidermal Growth Factor; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Microsomes; NADP; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Ischemically sensitive abdominal visceral afferents: response to cyclooxygenase blockade.
Topics: Abdomen; Afferent Pathways; Animals; Aspirin; Cats; Cyclooxygenase Inhibitors; Gallbladder; Indomethacin; Intestines; Ischemia; Liver; Mesentery; Nerve Endings; Nerve Fibers; Nerve Fibers, Myelinated; Pancreas; Stomach | 1991 |
Role of polyamines in gastroprotection induced by epidermal growth factor.
Topics: Animals; Aspirin; Dinoprostone; Eflornithine; Epidermal Growth Factor; Ethanol; Gastric Acid; Gastric Mucosa; Indomethacin; Pepsin A; Polyamines; Rats; Rats, Inbred Strains; Stomach; Stomach Diseases; Stress, Physiological | 1991 |
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans; Indomethacin; Male; Myocardial Infarction | 1991 |
Inhibitors of arachidonic acid metabolism: effects on rat striatal dopamine release and uptake.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carrier Proteins; Corpus Striatum; Cyclooxygenase Inhibitors; Dopamine; Dopamine Plasma Membrane Transport Proteins; Estrenes; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Phospholipases A; Phospholipases A2; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2 | 1991 |
Piroxicam, indomethacin and aspirin action on a murine fibrosarcoma. Effects on tumour-associated and peritoneal macrophages.
Topics: Animals; Antigens, Differentiation; Aspirin; Fibrosarcoma; Glucuronidase; Hematocrit; Indomethacin; Leukocyte Count; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Peritoneal Cavity; Phagocytosis; Piroxicam; Receptors, Fc; Receptors, IgG; Rosette Formation | 1991 |
Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells: II. A pathway involving arachidonic acid release, prostaglandin synthesis, and cyclic AMP accumulation.
Topics: Adenosine Triphosphate; Aminophylline; Animals; Arachidonic Acids; Aspirin; Carcinoma, Squamous Cell; Cell Line; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; GTP-Binding Proteins; Humans; Indomethacin; Mice; Mitosis; Pertussis Toxin; Phospholipases A; Phospholipases A2; Prostaglandins; Protein Kinase C; Signal Transduction; Time Factors; Virulence Factors, Bordetella | 1991 |
Arachidonic acid metabolites in normal and autoimmune mice do not influence lymphocyte-high endothelial venule interactions.
Topics: Animals; Arachidonic Acids; Aspirin; Autoimmunity; Binding Sites; Dinoprostone; Indomethacin; Lymph Nodes; Lymphocytes; Mice; Mice, Inbred CBA; SRS-A; Venules | 1991 |
Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diethylcarbamazine; Ibuprofen; Indomethacin; Mice; Piroxicam; Pneumonia; Radiation Injuries, Experimental; Tetrazoles | 1991 |
Effect of inhibitors of eicosanoid synthesis upon lymphocyte proliferation.
Topics: Animals; Aspirin; Caffeic Acids; Cells, Cultured; DNA Replication; Eicosanoids; Indomethacin; Lymph Nodes; Lymphocyte Activation; Male; Masoprocol; Quinacrine; Rats; T-Lymphocytes; Thymidine | 1991 |
Differences in the effects in the newborn piglet of various nonsteroidal antiinflammatory drugs on cerebral blood flow but not on cerebrovascular prostaglandins.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebrovascular Circulation; Ibuprofen; Indomethacin; Naproxen; Prostaglandins; Swine | 1991 |
Hydrogen peroxide is an intermediate in the platelet activation cascade triggered by collagen, but not by thrombin.
Topics: Aspirin; Calcium; Catalase; Collagen; Flow Cytometry; Fluoresceins; Humans; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Platelet Activation; Platelet Aggregation; Thrombin | 1991 |
Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase.
Topics: Adrenalectomy; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Aspirin; Chromatography, High Pressure Liquid; Chromones; Humans; Indomethacin; Interleukin-1; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Recombinant Proteins; SRS-A; Stimulation, Chemical; Stomach; Time Factors | 1991 |
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.
Topics: Acetaminophen; Aspirin; Blotting, Northern; Blotting, Western; Endothelium, Vascular; Epoprostenol; Humans; Indomethacin; Interleukin-1; Kinetics; Methionine; Prostaglandin-Endoperoxide Synthases; RNA, Messenger | 1991 |
Enhancement of murine susceptibility to oral lactate dehydrogenase-elevating virus infection by non-steroidal anti-inflammatory agents, and antagonism by misoprostol.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Aspirin; Diclofenac; Female; Indomethacin; Lactate dehydrogenase-elevating virus; Mice; Mice, Inbred Strains; Misoprostol; Virus Diseases | 1991 |
Differential effects of cyclooxygenase inhibitors on the cardiovascular response to hyperosmotic mannitol.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dogs; Female; Hemodynamics; Indomethacin; Infusions, Intravenous; Male; Mannitol; Meclofenamic Acid; Myocardial Contraction; Osmolar Concentration; Rabbits | 1991 |
Regeneration of vitamin E in human platelets.
Topics: Arachidonate 12-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Humans; Indomethacin; Kinetics; Oxidation-Reduction; Solubility; Vitamin E | 1991 |
[The treatment of pressure urticaria with anti-inflammatory agents].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Pressure; Urticaria | 1991 |
Inhibition of acute inflammation in the periphery by central action of salicylates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dexamethasone; Female; Indomethacin; Inflammation; Injections, Intraperitoneal; Injections, Intraventricular; Lysine; Mice; Mice, Inbred BALB C; Sodium Salicylate | 1991 |
Evidence that interleukin-1 and lipoxygenase metabolites mediate the lethal effect of complete Freund's adjuvant in adrenalectomized rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adjuvants, Immunologic; Adrenalectomy; Animals; Aspirin; Dexamethasone; Indomethacin; Interleukin-1; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Peritoneal Cavity; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
Effects of prostaglandin E2 and cyclooxygenase inhibitors on clustering and level of nicotinic acetylcholine receptor in mouse myotubes co-cultured with spinal cord explant.
Topics: Animals; Aspirin; Cell Communication; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Indomethacin; Kinetics; Masoprocol; Mice; Mice, Inbred Strains; Muscles; Organ Culture Techniques; Platelet Activating Factor; Receptors, Nicotinic; Spinal Cord | 1991 |
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance; Female; Flufenamic Acid; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged; Phenylbutazone; Prostaglandin-Endoperoxide Synthases | 1991 |
Biochemical and pharmacological studies of the mechanism of action of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone, Actinia tenebrosa.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cardiotonic Agents; Cnidaria; Guinea Pigs; Hemolysis; Indomethacin; Invertebrate Hormones; Male; Myocardial Contraction; Peptide Hydrolases; Phospholipases A; Phospholipases A2; Sea Anemones | 1990 |
Effect of anti-inflammatory drugs on the activity of antioxidant enzymes and in vivo peroxidation products in the liver and kidney of rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Catalase; Free Radicals; Glutathione Peroxidase; Hydrocortisone; Indomethacin; Kidney; Liver; Male; Peroxides; Phenylbutazone; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1990 |
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms | 1990 |
In vivo effects of nonsteroidal antiinflammatory drugs on rat skin and synovial mast cell-induced vasopermeability.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capillary Permeability; Cimetidine; Diphenhydramine; Indomethacin; Ketoprofen; Male; Mast Cells; Rats; Rats, Inbred Strains; Skin; Synovial Membrane | 1991 |
Antisecretory and anti-ulcer effects of morphine in rats after gastric mucosal aggression.
Topics: Animals; Aspirin; Depression, Chemical; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Morphine; Mucus; Naloxone; Rats; Rats, Inbred Strains; Stomach Ulcer; Taurocholic Acid | 1991 |
Pattern of rheumatic diseases in south India. IV. Clinical profile of juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Chronic Disease; Female; Humans; Ibuprofen; India; Indomethacin; Male | 1990 |
Effects of commonly used NSAID's on gastric mucosa. A clinico-endoscopic and histopathological study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastric Mucosa; Gastritis; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Oxyphenbutazone | 1990 |
A role for intracellular histamine in collagen-induced platelet aggregation.
Topics: Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epoprostenol; Histamine; Humans; In Vitro Techniques; Indomethacin; Metabolism, Inborn Errors; Methylhistidines; Microscopy, Electron; Phosphatidylethanolamines; Platelet Aggregation; Tetradecanoylphorbol Acetate | 1990 |
A biological method for studying the interaction between platelets and vascular endothelium.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Aspirin; Blood Platelets; Endothelium, Vascular; Epoprostenol; Imidazoles; Indomethacin; Leukotrienes; Lipid Peroxides; Platelet Adhesiveness; Rabbits; Superoxide Dismutase; Thrombosis; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Contrasting effects of norepinephrine and 5-hydroxytryptamine on contractility of abdominal aorta of two kidney-two clip hypertensive rats. Effects of inhibitors of arachidonic acid metabolic enzymes.
Topics: Animals; Aorta, Abdominal; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Epoprostenol; Hypertension, Renovascular; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin; Vasoconstriction | 1990 |
Endothelium-dependent effects of cigarette smoke components on tone of porcine intrapulmonary arteries in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotiana; Nicotine; Norepinephrine; Plants, Toxic; Pulmonary Artery; Smoke; Swine | 1990 |
Increased vasoconstrictor response to noradrenaline in femoral vascular bed of diabetic dogs. Is thromboxane A2 involved?
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; Femoral Vein; Indomethacin; Male; Norepinephrine; Organ Culture Techniques; Phentolamine; Thromboxane A2; Vasoconstriction | 1990 |
In vitro capacity of various cyclooxygenase inhibitors to revert immune suppression caused by radiation therapy for breast cancer.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Ketoprofen; Lymphocyte Activation; Lysine; Meclofenamic Acid; Middle Aged; Phytohemagglutinins | 1990 |
Studies on 1,2,3-triazole derivatives as in vitro inhibitors of prostaglandin synthesis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Indomethacin; Malondialdehyde; Prostaglandin Antagonists; Triazoles | 1990 |
Systemic toxicity in mice induced by localized porphyrin photodynamic therapy.
Topics: Animals; Aspirin; Blood Cell Count; Dihematoporphyrin Ether; Dose-Response Relationship, Radiation; Female; Hematoporphyrins; Indomethacin; Melanoma, Experimental; Mice; Mice, Inbred Strains; Photochemotherapy; Skin Pigmentation; Warfarin | 1990 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Heart; Heart Ventricles; Ibuprofen; Indomethacin; Maternal-Fetal Exchange; Pericardial Effusion; Pregnancy; Rats; Rats, Inbred Strains | 1990 |
Estimation of the in vivo effect of cyclooxygenase inhibitors on prostaglandin E2 levels in mouse brain.
Topics: Abdominal Muscles; Acetaminophen; Acetylcholine; Animals; Aspirin; Brain Chemistry; Brain Stem; Cerebral Cortex; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprostone; Hypothalamus; Ibuprofen; Indomethacin; Male; Mice; Microsomes; Nociceptors; Pain Measurement; Prostaglandin-Endoperoxide Synthases | 1990 |
Signal transduction by the platelet Fc receptor.
Topics: Acetophenones; Antibodies, Monoclonal; Antigens, Differentiation; Arachidonic Acids; Aspirin; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Indomethacin; Phosphatidylinositols; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Receptors, Fc; Receptors, IgG; Signal Transduction; Thrombin; Type C Phospholipases | 1990 |
Bradykinin-induced vasoconstriction of rat mesenteric arteries precontracted with noradrenaline.
Topics: Animals; Aspirin; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Eicosanoids; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Meclofenamic Acid; Mesenteric Arteries; Norepinephrine; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction | 1990 |
Meningoencephalitis and peripheral neuropathy complicating adult Still's disease.
Topics: Adult; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Meningoencephalitis; Peripheral Nervous System Diseases; Prednisone; Uveitis | 1990 |
Nonsteroidal anti-inflammatory drugs inhibit gastric peroxidase activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Hydrogen Peroxide; Hydrogen-Ion Concentration; Indomethacin; Lactoperoxidase; Mice; Mice, Inbred BALB C; Mitochondria; Peroxidase; Phenylbutazone; Potassium Iodide; Rats; Rats, Inbred Strains | 1990 |
Effects of non-steroidal anti-inflammatory drugs on human neutrophil NADPH oxidase in both whole cell and cell-free systems.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell-Free System; Enzyme Activation; Humans; Indomethacin; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Salicylates; Salicylic Acid; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Effects of some non-steroidal anti-inflammatory drug copper complexes on polymorphonuclear leukocyte oxidative metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Copper; Free Radical Scavengers; In Vitro Techniques; Indomethacin; Luminescent Measurements; Male; Neutrophils; Oxidation-Reduction; Pleurisy; Rats; Rats, Inbred Strains; Salicylates; Superoxides | 1990 |
Correlation of gastric mucous volume with levels of five prostaglandins after gastric mucosal injuries by NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Gastric Mucosa; Indomethacin; Male; Mucus; Prostaglandins; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Prostaglandins contribute to activation of baroreceptors in rabbits. Possible paracrine influence of endothelium.
Topics: Animals; Aspirin; Carotid Sinus; Endothelium, Vascular; Epoprostenol; Indomethacin; Male; Microscopy, Electron, Scanning; Pressoreceptors; Prostaglandins; Rabbits | 1990 |
The formalin test in mice: effect of formalin concentration.
Topics: Analgesics; Animals; Aspirin; Forelimb; Formaldehyde; Indomethacin; Male; Mice; Mice, Inbred Strains; Morphine; Nociceptors; Osmolar Concentration | 1990 |
Role of eicosanoids in the ocular response to intracameral hydrogen peroxide.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Ciliary Body; Cornea; Corneal Opacity; Dexamethasone; Eicosanoids; Hydrogen Peroxide; Indomethacin; Intraocular Pressure; Iris; Masoprocol; Rabbits | 1990 |
Adenosine-5'-triphosphate-induced sinus tachycardia mediated by prostaglandin synthesis via phospholipase C in the rabbit heart.
Topics: Adenosine Triphosphate; Animals; Apamin; Aspirin; Female; Heart; Indomethacin; Male; Myocardium; Neomycin; Perfusion; Pertussis Toxin; Prostaglandins; Rabbits; Receptors, Purinergic; Tachycardia, Sinus; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Modifications by endogenous prostaglandins of angiotensin II-induced contractions in dog and monkey cerebral and mesenteric arteries.
Topics: Angiotensin II; Animals; Aspirin; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Indomethacin; Macaca; Male; Mesenteric Arteries; Prostaglandins; Thromboxane A2; Vasoconstriction | 1990 |
Non-steroidal anti-inflammatory drug-copper complex modulation of polymorphonuclear leukocyte migration.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Indomethacin; Molecular Structure; Neutrophils; Organometallic Compounds; Pleurisy; Rats; Salicylates | 1990 |
Effects of various prostaglandin synthesis inhibitors on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinogens; Cricetinae; Female; Indomethacin; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pancreatitis; Phenylbutazone | 1990 |
Regulation of polyethylene glycol 400 intestinal permeability by endogenous and exogenous prostanoids. Influence of non-steroidal anti-inflammatory drugs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Drug Interactions; Indomethacin; Intestinal Absorption; Jejunum; Male; Permeability; Polyethylene Glycols; Prostaglandins E, Synthetic; Rats; Rats, Inbred F344 | 1990 |
Mucosal protective activity of activated aluminum complex.
Topics: Aluminum Hydroxide; Animals; Antacids; Aspirin; Cysteamine; Duodenal Ulcer; Ethanol; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Ligation; Magnesium Hydroxide; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Abnormal platelet hydrogen peroxide metabolism in aspirin hypersensitivity.
Topics: Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Immunoglobulin E; In Vitro Techniques; Indomethacin; Luminescent Measurements; Platelet Activation | 1990 |
Acetaminophen hepatotoxicity: is there a role for prostaglandin synthesis?
Topics: Acetaminophen; Animals; Aspirin; Chemical and Drug Induced Liver Injury; Glutathione; Hexobarbital; Indomethacin; Liver Diseases; Male; Mice; Mice, Inbred ICR; Necrosis; Osmolar Concentration; Prostaglandins; Sleep; Solutions; Xylitol | 1990 |
Modulation of substance P-induced bronchoconstriction by lipoxygenase metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Anesthesia; Animals; Anti-Inflammatory Agents; Aspirin; Bronchi; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substance P | 1985 |
Protection of irradiated parotid by prostaglandin synthesis inhibitors.
Topics: Amylases; Animals; Aspirin; Female; Indomethacin; Necrosis; Parotid Gland; Prostaglandin Antagonists; Radiation-Protective Agents; Rats; Rats, Inbred Strains | 1986 |
Augmentation of natural killer activity by neuraminidase treatment of lymphocytes from tumor-bearing mice.
Topics: Animals; Aspirin; Cytotoxicity, Immunologic; Dinoprostone; Indomethacin; Interferons; Killer Cells, Natural; Kinetics; Liver Neoplasms, Experimental; Lymphocytes; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Neuraminidase; Prostaglandins E; Spleen; T-Lymphocytes, Cytotoxic; Vibrio cholerae | 1986 |
Induction of natural killer cell activity in mice by injection of indomethacin.
Topics: Animals; Aspirin; Cell Line; Cytotoxicity, Immunologic; Dinoprostone; Indomethacin; Interferons; Killer Cells, Natural; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Peritoneal Cavity; Prostaglandins E | 1986 |
Role in kinin in rat epinephrine pulmonary edema (REPE).
Topics: Animals; Aprotinin; Aspirin; Enzyme Activation; Epinephrine; Humans; Indomethacin; Kallikreins; Kininogens; Kinins; Male; Pulmonary Edema; Rats; Rats, Inbred Strains; Trypsin Inhibitors | 1986 |
Interference with tolerance induction in vivo by inhibitors of prostaglandin synthesis.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Aspirin; Dinoprostone; gamma-Globulins; Immune Tolerance; Indomethacin; Male; Mice; Mice, Inbred A; Prostaglandins E; T-Lymphocytes; Time Factors | 1987 |
Differentiation of alpha 1-adrenergic receptors linked to phosphatidylinositol turnover and cyclic AMP accumulation in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkylating Agents; Animals; Aspirin; Brain; Brain Mapping; Calcium; Clonidine; Cyclic AMP; In Vitro Techniques; Indomethacin; Phenethylamines; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Tetralones | 1987 |
Treatment of mice with indomethacin leads to the appearance of a 125,000 dalton plasma protein with the characteristics of an acute phase reactant.
Topics: Acute-Phase Proteins; Animals; Aspirin; Electrophoresis, Polyacrylamide Gel; Female; Indomethacin; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mycobacterium bovis; Propionibacterium acnes; Sex Factors; Sulindac | 1987 |
Heterotopic ossification with total hip endoprostheses in various models of thrombosis prophylaxis.
Topics: Aspirin; Bone and Bones; Choristoma; Dextrans; Heparin; Hip Prosthesis; Humans; Indomethacin; Oxyphenbutazone; Postoperative Complications; Prospective Studies; Random Allocation; Thrombosis | 1988 |
Comparative studies on the effect of non-steroidal anti-inflammatory drugs (NSAID) on histamine release from mast cells of the rat and guinea pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Guinea Pigs; Histamine Release; Indomethacin; Mast Cells; Piroxicam; Rats; Rats, Inbred Strains | 1988 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aspirin; Calcium; Female; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Oxygen; Partial Pressure; Pregnancy; Propionates; Reference Values; Umbilical Arteries | 1988 |
Hydrogen peroxide and methyl mercury are primary stimuli of eicosanoid release in human platelets.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Eicosanoids; Epoprostenol; Humans; Hydrogen Peroxide; Iloprost; Imidazoles; Indomethacin; Methylmercury Compounds; Platelet Aggregation; Serotonin; Thrombin | 1989 |
Influence of nonsteroid anti-inflammatory drugs on lymphocyte subpopulation and on the primary humoral response in normothermic and feverish rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Dose-Response Relationship, Drug; Fever; Indomethacin; Lymphocyte Subsets; Male; Mefenamic Acid; Rabbits | 1989 |
Contraction of the rat isolated aorta caused by Clostridium perfringens alpha toxin (phospholipase C): evidence for the involvement of arachidonic acid metabolism.
Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Bacterial Toxins; Calcium-Binding Proteins; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Thromboxane B2; Thromboxane-A Synthase; Type C Phospholipases | 1989 |
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Development; Muscle, Smooth; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Pyrilamine; Saphenous Vein | 1989 |
Different modes of inhibition of rat gastric mucosal 6-keto-PGF1 alpha production by indomethacin, aspirin and aminopyrine.
Topics: 6-Ketoprostaglandin F1 alpha; Aminopyrine; Animals; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1989 |
Inhibition of human platelet function in vitro and ex vivo by acetaminophen.
Topics: Acetaminophen; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation Inhibitors; Serotonin; Thromboxane B2 | 1989 |
Optical spectra and kinetics of reactions of prostaglandin H synthase: effects of the substrates 13-hydroperoxyoctadeca-9,11-dienoic acid, arachidonic acid, N,N,N',N'-tetramethyl-p-phenylenediamine, and phenol and of the nonsteroidal anti-inflammatory dru
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzophenones; Bromobenzenes; Indomethacin; Kinetics; Linoleic Acids; Lipid Peroxides; Male; Phenol; Phenols; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Spectrophotometry; Tetramethylphenylenediamine | 1989 |
Prostaglandins in carotid sinus enhance baroreflex in rabbits.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Pressure; Carotid Sinus; Epoprostenol; Female; In Vitro Techniques; Indomethacin; Male; Pressoreceptors; Rabbits; Reference Values; Reflex | 1989 |
The microvascular effects of photodynamic therapy: evidence for a possible role of cyclooxygenase products.
Topics: Animals; Aspirin; Indomethacin; Male; Microcirculation; Photochemotherapy; Prostaglandin-Endoperoxide Synthases; Rats; Regional Blood Flow | 1989 |
Effect of nordihydroguaiaretic acid on cultured rat and human glioma cell proliferation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Catechols; Cell Division; Cell Line; Cell Survival; DNA Replication; Glioma; Humans; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles; Rats; Tumor Cells, Cultured; Umbelliferones | 1989 |
Alveolar macrophages and eicosanoids but not neutrophils, mediate bronchoconstriction induced by FMLP in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aerosols; Animals; Aspirin; Bronchi; Cyclooxygenase Inhibitors; Eicosanoids; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase; Macrophages; Male; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Alveoli; Trachea; Vinblastine | 1989 |
Prostaglandin E1 modifies porcine cerebral arterial tone through cyclooxygenase related eicosanoid(s) release.
Topics: Animals; Aspirin; Cerebral Arteries; Eicosanoic Acids; Enzyme Inhibitors; Indomethacin; Muscle Tonus; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Swine | 1989 |
Thromboxane is produced in response to intracoronary infusions of complement C5a in pigs. Cyclooxygenase blockade does not reduce the myocardial ischemia and leukocyte accumulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Complement C5a; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Female; Indomethacin; Injections, Intra-Arterial; Leukocyte Count; Leukocytes; Male; Myocardium; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane B2; Thromboxanes | 1989 |
Effect of flunixin meglumine on prostaglandin F2 alpha synthesis and metabolism in the pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clonixin; Cyclooxygenase Inhibitors; Dinoprost; Estrus; Female; Indomethacin; Male; Mefenamic Acid; Nicotinic Acids; Swine | 1989 |
Evaluation of post-cardiopulmonary bypass Sonoclot signatures in patients taking nonsteroidal anti-inflammatory drugs.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Viscosity; Cardiopulmonary Bypass; Evaluation Studies as Topic; Fibrinogen; Humans; Ibuprofen; Indomethacin; Partial Thromboplastin Time; Platelet Count; Protamines; Prothrombin Time; Whole Blood Coagulation Time | 1989 |
The role of prostaglandins in masculine differentiation: modulation of prostaglandin levels in the differentiating genital tract of the fetal mouse.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyproterone; Cyproterone Acetate; Dinoprostone; Female; Genitalia, Female; Genitalia, Male; Gestational Age; Indomethacin; Male; Mice; Prostaglandins; Sex Differentiation; Testosterone | 1989 |
On the mechanism of aspirin asthma.
Topics: Aspirin; Asthma; Humans; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Lysine | 1989 |
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Aspirin; Cells, Cultured; Copper; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Lipoxygenase; Masoprocol; Oxidation-Reduction; Rabbits; Recombinant Proteins; Superoxide Dismutase; Superoxides | 1989 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
Prostaglandin E2 inhibits and indomethacin and aspirin enhance, A23187-stimulated leukotriene B4 synthesis by rat peritoneal macrophages.
Topics: Animals; Aspirin; Calcimycin; In Vitro Techniques; Indomethacin; Leukotriene B4; Macrophages; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Prostacyclin as a potent effector of adipose-cell differentiation.
Topics: Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Differentiation; Cell Line; Cyclic AMP; Epoprostenol; Humans; Indomethacin; Mice; Mitosis; Prostaglandins F; Prostaglandins, Synthetic; Rats | 1989 |
A sensitive in vivo platelet function test in rats based on intravenously injected collagenase.
Topics: Animals; Aspirin; Dipyridamole; Imidazoles; Indomethacin; Injections, Intravenous; Ketanserin; Microbial Collagenase; Mopidamol; Platelet Count; Platelet Function Tests; Rats; Rats, Inbred Strains | 1989 |
Gastric antisecretory and antiulcer/cytoprotective effects of 2-cyano-3-(ethylthio-3-methylthio)-2-propenoic acid methyl ester.
Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Cyanoacrylates; Ethanol; Gastric Acid; Gastric Emptying; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; In Vitro Techniques; Indomethacin; Male; Pentagastrin; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1989 |
Influence of cardioprotective cyclooxygenase and lipoxygenase inhibitors on peroxidative injury to myocardial-membrane phospholipid.
Topics: Aspirin; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipid Peroxidation; Lipid Peroxides; Lipoxygenase Inhibitors; Membrane Lipids; Myocardial Reperfusion Injury; Naproxen; Sulfinpyrazone; Superoxides; Time Factors; Xanthine Oxidase | 1989 |
UVB erythema inhibited by topically applied substances.
Topics: Administration, Topical; Adult; Aged; Aspirin; Betamethasone; Butylated Hydroxytoluene; Diphenhydramine; Erythema; Female; Humans; Hydrocortisone; Indomethacin; Male; Middle Aged; Skin; Ultraviolet Rays | 1989 |
Indirect evidence for a role of prostaglandins as second messengers of the prejunctional effect of opioids in guinea-pig ventricular preparations.
Topics: Animals; Aspirin; Dynorphins; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardial Contraction; Narcotics; Peptide Fragments; Prostaglandins; Refractory Period, Electrophysiological; Second Messenger Systems | 1989 |
Effects of cryptolepine alone and in combination with dipyridamole on a mouse model of arterial thrombosis.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Animals; Aspirin; Dipyridamole; Fibrinolytic Agents; Indole Alkaloids; Indoles; Indomethacin; Male; Mice; Quinolines | 1989 |
Effects of non-psychotropic drugs on conditioned behavior of cats.
Topics: Administration, Oral; Amantadine; Animals; Aspirin; Behavior, Animal; Cats; Conditioning, Psychological; Feeding Behavior; Female; Histamine H1 Antagonists; Indomethacin; Male; Phenoxybenzamine | 1989 |
Some properties of calcium-induced contraction in the isolated human and guinea-pig tracheal smooth muscle.
Topics: Aged; Animals; Aspirin; Calcium; Chromones; Female; Guinea Pigs; Humans; Indomethacin; Ion Channels; Male; Middle Aged; Muscle Contraction; Muscle Tonus; Muscle, Smooth; SRS-A; Trachea; Verapamil | 1985 |
The effect of indomethacin, aspirin, and ibuprofen on bone ingrowth into a porous-coated implant.
Topics: Animals; Aspirin; Bone and Bones; Chromium Alloys; Dose-Response Relationship, Drug; Femur; Ibuprofen; Indomethacin; Injections, Subcutaneous; Prostheses and Implants; Rabbits; Surface Properties; Time Factors | 1989 |
Comparison of high-performance liquid chromatography and the Abbott fluorescent polarization radioimmunoassay in the measurement of methotrexate.
Topics: Administration, Oral; Aspirin; Chromatography, High Pressure Liquid; Drug Interactions; Fluorescence Polarization; Half-Life; Humans; Indomethacin; Injections, Intravenous; Methotrexate; Radioimmunoassay; Reagent Kits, Diagnostic; Rheumatic Diseases | 1989 |
Gastroprotective activity of ginger zingiber officinale rosc., in albino rats.
Topics: Animals; Aspirin; Drugs, Chinese Herbal; Ethanol; Female; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Inbred Strains; Reserpine; Sodium Chloride; Sodium Hydroxide; Stomach Ulcer; Stress, Physiological | 1989 |
Mechanism of anti-ulcer effect of calf blood extract.
Topics: Actihaemyl; Animals; Anti-Ulcer Agents; Aspirin; Bicarbonates; Biomechanical Phenomena; Duodenum; Electrophysiology; Ethanol; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Tissue Extracts | 1989 |
Comparative acute effects of aspirin, diflunisal, ibuprofen and indomethacin on renal function in healthy man.
Topics: Adult; Aspirin; Diflunisal; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Function Tests; Male | 1989 |
Induction of platelet aggregation in vitro by microbubbles of nitrogen.
Topics: Adenosine Diphosphate; Aspirin; Drug Synergism; Epinephrine; Gases; Humans; In Vitro Techniques; Indomethacin; Ketanserin; Nitrogen; Platelet Aggregation; Serotonin; Yohimbine | 1989 |
In vitro reactivity of dog cavernous carotid artery to stretch and adrenergic stimulation.
Topics: Acetylcholine; Animals; Aspirin; Carotid Artery, Internal; Dogs; Electric Stimulation; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Serotonin; Tetrodotoxin | 1989 |
Study on the in vitro assay method for evaluating the inhibitory effect of various substances on the production of plasma kallikrein.
Topics: Aminopyrine; Aspirin; Humans; Ibuprofen; Indomethacin; Kallikreins; Ketoprofen; Kinetics; Kinins; Morphine; Pentazocine; Prekallikrein | 1989 |
Qualitative and quantitative studies on the nucleotides of intestinal mucosa.
Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Indomethacin; Intestinal Mucosa; Ischemia; Jejunum; Liver; Male; Myocardium; Nucleotides; Rats; Rats, Inbred Strains | 1989 |
[Pharmacological study of kako-bushi-matsu: analgesic action and acute toxicity].
Topics: Analgesics; Animals; Aspirin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Ibuprofen; Indomethacin; Lethal Dose 50; Male; Mice; Rats; Rats, Inbred Strains | 1989 |
[Relationships between ethanol-induced sleep and aspirin, indomethacin or PGE2 in inbred rats].
Topics: Animals; Aspirin; Dinoprostone; Ethanol; Indomethacin; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sleep | 1989 |
[Ethanol-induced discriminative stimulus properties in inbred rats with reference to aspirin, indomethacin and desipramine].
Topics: Animals; Aspirin; Desipramine; Discrimination, Psychological; Dose-Response Relationship, Drug; Indomethacin; Male; Pentobarbital; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1989 |
Effects of aspirin-like drugs on Walker 256 tumor growth and cachexia in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; Cachexia; Carcinoma 256, Walker; Cell Division; Ibuprofen; Indomethacin; Male; Neoplasm Transplantation; Prostaglandin Antagonists; Prostaglandins E; Rats | 1989 |
[Preliminary studies on phagocytosis of cultured mouse peritoneal macrophage exposed to anti-inflammatory agents].
Topics: Animals; Aspirin; Cells, Cultured; Dexamethasone; Indomethacin; Macrophages; Mice; Phagocytosis | 1989 |
[Clinical evaluation of the control of antiplatelet therapy through platelet aggregation rate on polycythemia vera associated with thrombocytosis and erythromelalgia].
Topics: Aspirin; Drug Evaluation; Erythromelalgia; Female; Fingers; Humans; Indomethacin; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polycythemia Vera; Thrombocytosis | 1989 |
A continuous monitoring of mucosal integrity and secretory activity in rat stomach: a preparation using a lucite chamber.
Topics: Animals; Aspirin; Equipment Design; Ethanol; Gastric Mucosa; Indomethacin; Male; Potentiometry; Rats; Rats, Inbred Strains; Sodium Chloride; Taurocholic Acid; Vasopressins | 1989 |
Effects of nonsteroidal antiinflammatory drugs on collagen biosynthesis of cultured chondrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage, Articular; Cells, Cultured; Chick Embryo; Collagen; Indomethacin; Propionates | 1989 |
Role of prostaglandins in alcohol teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Ethanol; Female; Indomethacin; Mice; Mice, Inbred C57BL; Pregnancy; Pregnancy, Animal; Prostaglandin Antagonists; Prostaglandins | 1989 |
Indomethacin inhibits the effects of oestrogen in the anterior pituitary gland of the rat.
Topics: Animals; Arachidonic Acids; Aspirin; Dinoprostone; Estradiol; Estrogen Antagonists; Indomethacin; Pituitary Gland, Anterior; Progesterone; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1989 |
Mechanisms of action of eperisone on isolated dog saphenous arteries and veins.
Topics: Animals; Arteries; Aspirin; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Relaxation; Muscles; Propiophenones; Regional Blood Flow; Saphenous Vein; Vasodilator Agents | 1989 |
Effect of NSAIDS on serum electrolytes and osmolality.
Topics: Animals; Aspirin; Calcium; Chlorides; Electrolytes; Hematocrit; Indomethacin; Magnesium; Osmolar Concentration; Phosphates; Potassium; Rabbits; Rats; Reference Values; Sodium | 1989 |
Effects of the novel anti-ulcer agent 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine on experimental ulcers and gastric secretion in rats.
Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Epirizole; Ethanol; Gastric Acid; Gastric Mucosa; Immersion; Indomethacin; Male; Perfusion; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological; Xanthines | 1989 |
Indomethacin and acetylsalicylic acid block neurogenic plasma protein extravasation in rat dura mater.
Topics: Animals; Aspirin; Blood Proteins; Dexamethasone; Dinoprostone; Dura Mater; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; Female; Ganglia; Indomethacin; Male; Nervous System; Rats; Rats, Inbred Strains; Technetium Tc 99m Aggregated Albumin; Trigeminal Nerve | 1989 |
The mode of action of indomethacin, aspirin and melatonin on the blockage of the first ovulation in immature rat pretreated with PMSG.
Topics: Animals; Aspirin; Chorionic Gonadotropin; Dinoprost; Female; Gonadotropins; Gonadotropins, Equine; Indomethacin; Melatonin; Ovulation; Rats; Rats, Inbred Strains | 1989 |
The differentiation of NSAIDs and prostaglandin action using a mechanical visceral pain model in the rat.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug; Indomethacin; Male; Mefenamic Acid; Pain; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Inbred Strains | 1989 |
Cytoprotective and antiulcer activities of the antacid magaldrate in the rat.
Topics: Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Aspirin; Cell Survival; Cysteamine; Dinoprostone; Ethanol; Gastric Juice; Indomethacin; Magnesium; Magnesium Hydroxide; Male; Rats; Rats, Inbred Strains; Serotonin; Stomach Ulcer; Sucralfate | 1989 |
Possible role of inhibition of glutathione S-transferase in the partial reversal of chlorambucil resistance by indomethacin in a Chinese hamster ovary cell line.
Topics: Animals; Aspirin; Cell Line; Cell Survival; Chlorambucil; Cricetinae; Cricetulus; Drug Resistance; Female; Glutathione Transferase; Immunoblotting; Indomethacin; Kinetics; Ovary | 1989 |
Possible role of prostaglandins as negative regulators in growth stimulation by tumor necrosis factor and epidermal growth factor in human fibroblasts.
Topics: Arachidonic Acids; Aspirin; Cell Division; Cell Line; Cells, Cultured; Child, Preschool; Epidermal Growth Factor; Fibroblasts; Humans; Indomethacin; Prostaglandins; Tumor Necrosis Factor-alpha | 1989 |
Effects of NSAID on collagen and proteoglycan synthesis of cultured chondrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage; Cells, Cultured; Chick Embryo; Collagen; Indomethacin; Propionates; Proteoglycans | 1989 |
Arachidonic acid and LTB4 enhance aggregation of psoriatic peripheral blood mononuclear leukocytes in vitro.
Topics: Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Aggregation; Female; Humans; In Vitro Techniques; Indomethacin; Leukotriene B4; Male; Masoprocol; Middle Aged; Monocytes; Psoriasis | 1987 |
Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils.
Topics: Aspirin; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; SRS-A | 1987 |
Influence of cyclooxygenase inhibitors and of lithium on the positive inotropic effect mediated by alpha 1-adrenoceptors in guinea-pig left atrium.
Topics: Animals; Aspirin; Calcium; Cyclooxygenase Inhibitors; Drug Interactions; Epinephrine; Guinea Pigs; In Vitro Techniques; Indomethacin; Inositol Phosphates; Lithium; Male; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, alpha; Reserpine; Sotalol; Stimulation, Chemical | 1987 |
Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses.
Topics: Animals; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Injections, Spinal; Male; Morphine; Pain; Phentolamine; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Spinal Cord; Synapses; Synaptic Transmission | 1988 |
Prostaglandins do not mediate the inhibitory effects of angiotensins II and III on autonomic neurotransmission in the rabbit vas deferens.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Angiotensin III; Animals; Aspirin; Autonomic Nervous System; Drug Synergism; Indomethacin; Male; Prostaglandins E; Rabbits; Synaptic Transmission; Vas Deferens | 1988 |
Growth hormone-releasing factor (GRF) stimulates PGE2 production in rat anterior pituitary. Evidence for a PGE2 involvement in GRF-induced GH release.
Topics: Animals; Aspirin; Dinoprostone; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Indomethacin; Male; Pituitary Gland, Anterior; Prostaglandins; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Thromboxanes | 1985 |
Effects of N-(3-[3-(1-piperidinylmethyl)phenoxy]propyl)-acetoxyacetamide hydrochloride (TZU-0460), a histamine H2-receptor antagonist, on gastric acid secretion and ulcer formation.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Cysteamine; Dogs; Gastric Acid; Histamine; Histamine H2 Antagonists; Humans; Indomethacin; Male; Pentagastrin; Rats; Rats, Inbred Strains; Reserpine; Stomach Ulcer; Stress, Psychological | 1985 |
Effect of intragastric pH, prostaglandins and prostaglandin synthesis inhibitors on the release of gastrin and somatostatin into the gastric lumen of anaesthetized rats.
Topics: Alprostadil; Animals; Aspirin; Atropine; Dinoprostone; Electric Stimulation; Gastric Mucosa; Gastrins; Hydrogen-Ion Concentration; Indomethacin; Male; Prostaglandins; Prostaglandins A; Prostaglandins E; Pyloric Antrum; Rats; Rats, Inbred Strains; Somatostatin; Vagus Nerve | 1986 |
Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Epoprostenol; Heart Atria; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Methoxamine; Myocardial Contraction; Rats; Rats, Inbred Strains; Thromboxanes | 1986 |
[Occurrence of drug reactions].
Topics: Acetaminophen; Adult; Anaphylaxis; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Emergencies; Erythromycin; Female; Glafenine; Humans; Indomethacin; Italy; Male; Penicillins; Propionates; Prospective Studies; Pyridazines; Rifampin; Urticaria; Vitamin B Complex | 1986 |
The role of pharmacologic agents in the prevention or treatment of allergic food disorders.
Topics: Administration, Oral; Adult; Aspirin; Beclomethasone; Child; Cromolyn Sodium; Dermatitis, Atopic; Food Hypersensitivity; Histamine H1 Antagonists; Humans; Ibuprofen; Indomethacin; Infant; Ketotifen; Nifedipine | 1986 |
Contractile and relaxant effects of jellyfish toxin on the vascular and intestinal tissues.
Topics: Animals; Aspirin; Cnidaria; Cnidarian Venoms; Endothelium; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Prostaglandins; Rats; Scyphozoa; Vasomotor System | 1987 |
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Dimaprit; Gastric Acid; Gastric Mucosa; Indomethacin; Ligation; Male; Muscle Contraction; Norepinephrine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Reserpine; Stomach Ulcer; Stress, Physiological; Thiourea; Yohimbine | 1987 |
[Drug therapy of dysmenorrhea].
Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Magnesium; Mefenamic Acid; Models, Biological; Naproxen; Progestins | 1988 |
[Liver regeneration and the immune system. III. Suppressor activity of splenic adherent cells activated in vivo by liver regeneration].
Topics: Animals; Aspirin; Female; Hepatectomy; Immune Tolerance; Indomethacin; Liver Regeneration; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Spleen; T-Lymphocytes, Regulatory | 1986 |
Aspirin inhibits phospholipase C.
Topics: Annexins; Aspirin; Cycloheximide; Dactinomycin; Glycoproteins; Humans; Indomethacin; Salicylates; Type C Phospholipases | 1986 |
Antipain or leupeptin in combination with aspirin or indomethacin synergistically inhibit human platelet activation by thrombin and trypsin.
Topics: Antipain; Aspirin; Blood Platelets; Drug Synergism; Humans; In Vitro Techniques; Indomethacin; Leupeptins; Oligopeptides; Thrombin; Trypsin | 1987 |
Gastric anti-ulcer and cytoprotective effect of selenium in rats.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dimaprit; Ethanol; Female; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Rats; Rats, Inbred Strains; Reserpine; Selenious Acid; Selenium; Stomach Ulcer; Thiourea | 1988 |
Pharmacological modulation of localized inflammatory reactions: the nonsteroidal anti-inflammatory drug as an adjunct to therapy.
Topics: Animals; Arthus Reaction; Aspirin; Capillary Permeability; Female; Hemorrhage; Indomethacin; Inflammation; Leukocytes; Rabbits | 1988 |
Human gamma interferon induction by staphylococcal protein A: effector cells, kinetics and the effect of prostaglandin, indomethacin, ibuprofen and aspirin.
Topics: Aspirin; Dinoprostone; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Interferon-gamma; Kinetics; Monocytes; Prostaglandins E; Prostaglandins E, Synthetic; Staphylococcal Protein A; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1988 |
Characterization of a myopathy caused by prostaglandin dysfunction.
Topics: Adenosine Triphosphatases; Animals; Aspirin; Chick Embryo; Humans; Indomethacin; Muscles; Muscular Dystrophies; Muscular Dystrophy, Animal; Prostaglandins; Prostaglandins E | 1988 |
Two distinct effects of oxygen on vascular tone in isolated porcine coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Histamine Antagonists; Indomethacin; Isoproterenol; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Oxygen; Phentolamine; Potassium Chloride; Prostaglandins; Receptors, Adrenergic, beta; Swine; Tripelennamine; Vasoconstriction | 1985 |
Human endothelial cells modulate granulocyte adherence and chemotaxis.
Topics: Aspirin; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Cyclic AMP; Cyclooxygenase Inhibitors; Endothelium; Epoprostenol; Granulocytes; Humans; Indomethacin; Time Factors; Umbilical Veins | 1985 |
Comparison of the effects of some compounds on human neutrophil degranulation and leukotriene B4 and thromboxane B2 synthesis.
Topics: Arachidonic Acids; Aspirin; Calcimycin; Humans; In Vitro Techniques; Indomethacin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylbutazone; Thromboxane B2; Thromboxanes | 1985 |
Role of prostaglandins in the activity of some cardiovascular drugs.
Topics: Angiotensin II; Antihypertensive Agents; Aspirin; Captopril; Dinoprostone; Dipyridamole; Epoprostenol; Humans; Indomethacin; Kinins; Nitroglycerin; Peptidyl-Dipeptidase A; Platelet Aggregation; Prostaglandins; Prostaglandins E; Thromboxane-A Synthase | 1985 |
Differential effect of platelet inhibitors in normal and in hypercholesterolaemic subjects.
Topics: Adult; Aspirin; Cyclic AMP; Dipyridamole; Epoprostenol; Humans; Hypercholesterolemia; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation | 1985 |
The response of human carcinoma cell lines to gamma-linolenic acid with special reference to the effects of agents which influence prostaglandin and thromboxane synthesis.
Topics: Alprostadil; Aspirin; Cell Division; Cell Line; Cell Survival; gamma-Linolenic Acid; Humans; Imidazoles; Indomethacin; Linolenic Acids; Neoplasms; Prostaglandins; Prostaglandins E; Thromboxane A2; Thromboxanes | 1985 |
Prostanoid modulation (mediation?) of certain behavioral effects of ethanol.
Topics: Alcoholism; Alprostadil; Animals; Aspirin; Brain; Ethanol; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Humans; Ibuprofen; Indomethacin; Linoleic Acids; Linolenic Acids; Male; Mice; Oenothera biennis; Plant Oils; Prostaglandins; Prostaglandins E; Prostanoic Acids; Substance Withdrawal Syndrome | 1985 |
Modes of action of aspirin-like drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Calcium; Cell Aggregation; Complement C5; Cyclic AMP; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Lymphocyte Activation; Neutrophils; Piroxicam; Prostaglandin Antagonists; Salicylates; Superoxides; Thiazines; Thromboxane A2 | 1985 |
Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Bucladesine; Carrageenan; Dinoprostone; Dipyrone; Edema; Hyperalgesia; Hyperesthesia; Indomethacin; Isoproterenol; Male; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Effects of arachidonic acid on the metabolism of eicosapentaenoic acid in washed human platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Carbon Radioisotopes; Eicosapentaenoic Acid; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Kinetics; Prostaglandins G | 1985 |
Effects of aspirin, indomethacin, and sodium salicylate on human erythrocyte membranes as detected with electron spin resonance spectroscopy.
Topics: Aspirin; Blood Coagulation; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Female; Humans; Indomethacin; Kinetics; Male; Membrane Fluidity; Salicylates; Salicylic Acid; Sex Factors; Thermodynamics | 1985 |
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Duodenum; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Heart Rate; Histamine; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Omeprazole; Peptic Ulcer; Rabbits; Rats; Stress, Physiological | 1986 |
Effects of inhibitors of arachidonic acid metabolism on intercellular adhesion of SV40-3T3 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cell Transformation, Viral; Cells, Cultured; Cyclooxygenase Inhibitors; Indomethacin; Masoprocol; Mice; Quinacrine; Simian virus 40 | 1986 |
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Enzyme Activation; Humans; Indomethacin; Isoquinolines; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Piperazines; Pyrazoles; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Indomethacin induces the suppression of plasma neutral proteinase activity in mice: possible relationship to efficacy as an anti-inflammatory drug and induction of alterations in the immune system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chlorides; Dose-Response Relationship, Drug; Endopeptidases; Female; Immune System; Indomethacin; Lipopolysaccharides; Lithium; Lithium Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasms, Experimental; Neprilysin; Peptide Hydrolases; Protease Inhibitors; Spleen | 1986 |
Angiotensin II: preferential efferent constriction?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Dogs; Female; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Punctures; Sodium Chloride; Vasoconstriction | 1986 |
Cell cycle-dependent inhibition of DNA synthesis by prostaglandin I2 in cultured rabbit aortic smooth muscle cells.
Topics: Animals; Aorta; Aspirin; Cell Cycle; Cell Division; DNA; Dose-Response Relationship, Drug; Epoprostenol; Indomethacin; Male; Muscle, Smooth, Vascular; Prostaglandins E; Rabbits; Thymidine | 1988 |
The effect of indomethacin and aspirin on alkaline phosphatase secretion and [3H]thymidine incorporation by human osteoblasts.
Topics: Alkaline Phosphatase; Aspirin; Calcitriol; Cell Survival; Cells, Cultured; Humans; Indomethacin; Insulin; Osteoblasts; Thymidine | 1988 |
Comparative mucosal protective properties of misoprostol, cimetidine, and sucralfate.
Topics: Alprostadil; Aluminum; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Ethanol; Gastric Mucosa; Indomethacin; Male; Misoprostol; Rats; Stress, Physiological; Sucralfate; Taurocholic Acid | 1986 |
Cytoprotective effect of free radical scavengers against mucosal damage produced by different antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Ascorbic Acid; Aspirin; Diclofenac; Female; Free Radicals; Gastric Mucosa; Indomethacin; Male; Penicillamine; Quinolines; Rats; Solubility; Thioctic Acid; Vitamin A; Vitamin E | 1986 |
Role of prostaglandin release in the response of tight epithelia to Ca2+ ionophores.
Topics: Animals; Aspirin; Biological Transport, Active; Calcimycin; Calcium; Chlorides; Dinoprostone; Epithelium; Ethers; Indomethacin; Ionomycin; Prostaglandins; Prostaglandins E; Rana catesbeiana; Rana pipiens; Skin; Sodium; Urinary Bladder | 1986 |
Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system.
Topics: ABO Blood-Group System; Animals; Aspirin; Blood; Cattle; Dactinomycin; Dinoprostone; Enzyme Induction; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Monocytes; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Thromboxane A2; Thromboxane B2 | 1986 |
The arachidonic acid cascade is involved in the masculinizing action of testosterone on embryonic external genitalia in mice.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cortisone; Cyproterone; Estradiol; Female; Genitalia, Female; Genitalia, Male; Indomethacin; Male; Mice; Morphogenesis; Phenytoin; Testosterone | 1986 |
Prostacyclin and steroidogenesis in goat ovarian cell types in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Estradiol; Female; Goats; In Vitro Techniques; Indomethacin; Ovary; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Steroids; Trapidil | 1986 |
Time-dependent inhibition of platelet cyclooxygenase by indomethacin is slowly reversible.
Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Kinetics; Male; Microsomes; Thromboxane B2 | 1986 |
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones | 1986 |
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Circulation; Coronary Disease; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Ibuprofen; Indomethacin; Male; Myocardial Contraction; Myocardium; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1986 |
Cyclooxygenase inhibitors promote the leukotriene C4 induced release of beta-glucuronidase from rat peritoneal macrophages: prostaglandin E2 suppresses.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Glucuronidase; Indomethacin; Kinetics; Macrophages; Male; Prostaglandins E; Rats; Rats, Inbred Strains; SRS-A | 1986 |
In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Platelet Aggregation; Pyrazoles; Sodium Salicylate; Thromboxane B2 | 1986 |
Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dogs; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotrienes; Lipid Peroxides; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine | 1986 |
Pharmacological modulation of the effects of N-formyl-L-methionyl-L-leucyl-L-phenylalanine in guinea-pigs: involvement of the arachidonic acid cascade.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Cell Count; Blood Platelets; Bronchi; Female; Guinea Pigs; Indomethacin; Lung; Male; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Pyrazoles; Thromboxane B2 | 1986 |
[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angina Pectoris; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Exercise Test; Female; Hemodynamics; Humans; Indomethacin; Male; Middle Aged; Nitroglycerin; Prostaglandins; Prostaglandins E | 1986 |
Aspirin-induced gastric injury in the rat: histologic changes and sucralfate cytoprotection.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gastric Mucosa; Indomethacin; Kinetics; Male; Rats; Rats, Inbred Strains; Sucralfate | 1987 |
Tumor necrosis factor-alpha (cachectin) stimulates bone resorption in mouse calvaria via a prostaglandin-mediated mechanism.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Calcium; Cyclooxygenase Inhibitors; Dinoprostone; Glycoproteins; Ibuprofen; Indomethacin; Mice; Organ Culture Techniques; Piroxicam; Prostaglandins E; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1987 |
Prostaglandins in the semicircular canal of the frog.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Dinoprostone; Epoprostenol; In Vitro Techniques; Indomethacin; Potassium; Prostaglandins E; Rana esculenta; Semicircular Canals; Sodium; Streptomycin | 1987 |
Effects of cyclooxygenase inhibition on pulmonary vascular responses to serotonin.
Topics: Animals; Aspirin; Blood Pressure; Capillaries; Cyclooxygenase Inhibitors; Dogs; Indomethacin; Lung; Meclofenamic Acid; Norepinephrine; ortho-Aminobenzoates; Pulmonary Artery; Pulmonary Circulation; Serotonin; Vascular Resistance | 1987 |
Prostaglandin synthesis and early biochemical events in the liver cells during the acute-phase response.
Topics: Acute-Phase Reaction; Animals; Aspirin; Dinoprost; Dinoprostone; Indomethacin; Inflammation; Liver; Male; Nucleic Acid Precursors; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; RNA Precursors; RNA, Messenger; Turpentine | 1987 |
Effects of anti-inflammatory drugs on cartilage recovery from catabolin-induced degradation.
Topics: Anti-Inflammatory Agents; Aspirin; Cartilage; Extracellular Matrix; Gold Sodium Thiomalate; Humans; Hydrocortisone; Hydroxyproline; Indomethacin; Interleukin-1; Interleukin-1beta; Proteoglycans | 1987 |
Toxicity of tumor necrosis factor is synergistic with gamma-interferon and can be reduced with cyclooxygenase inhibitors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Cyclooxygenase Inhibitors; Drug Synergism; Glycoproteins; Granulocytes; Hematopoietic Stem Cells; Indomethacin; Interferon-gamma; Intestines; Lipoxygenase Inhibitors; Liver; Lung; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Recombinant Proteins; Spleen; Tumor Necrosis Factor-alpha | 1987 |
Platelet aggregation by group B streptococci.
Topics: Aspirin; Blood Platelets; Edetic Acid; Humans; Indomethacin; L-Lactate Dehydrogenase; Platelet Aggregation; Platelet Count; Quinacrine; Serotonin; Streptococcus agalactiae | 1987 |
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Products; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pyrazoles; Trachea | 1987 |
Identification of novel arachidonic acid metabolites formed by prostaglandin H synthase.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Male; Mass Spectrometry; Microsomes; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Prostaglandins H; Seminal Vesicles; Spectrophotometry, Ultraviolet | 1987 |
[Contractile response of segments of the coronary arteries to histamine and angiotensin II in the presence of anthocyanosides of myrtillus].
Topics: Angiotensin II; Animals; Anthocyanins; Aspirin; Cattle; Coronary Vessels; Histamine Antagonists; Indomethacin; Lysine; Plants; Vasoconstriction | 1987 |
Sustained increase in the proliferation of rat colonic mucosa during chronic treatment with aspirin.
Topics: Animals; Aspirin; Cell Division; Colon; Dinoprostone; DNA; Epithelium; Female; Indomethacin; Intestinal Mucosa; Lipoxygenase; Prostaglandins E; Rats; Rats, Inbred Strains; Thymidine | 1988 |
Role of prostaglandins in blood-induced vasoconstriction of canine cerebral arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood; Cerebral Arteries; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dogs; Female; Ibuprofen; Indomethacin; Male; Meclofenamic Acid; Papaverine; Prostaglandins; Prostaglandins E; Prostaglandins F; Vasoconstriction | 1988 |
Gastric mucosal protection by new aryl sulfhydryl drugs.
Topics: Animals; Aspirin; Chronic Disease; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Female; Gastric Acid; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Pepsin A; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1988 |
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac | 1987 |
Prostaglandin synthesis by squamous carcinoma cells of head and neck, and its inhibition by non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Carcinoma, Squamous Cell; Cell Line; Dinoprostone; Facial Neoplasms; Humans; Ibuprofen; Indomethacin; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Tongue Neoplasms | 1987 |
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
The role of arachidonic acid metabolism in IL-3-induced proliferation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cell Division; Cell Line; Indomethacin; Interleukin-3; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Propionates; Pyrazoles | 1988 |
Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells.
Topics: Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Azides; Catalase; Cyclooxygenase Inhibitors; Dapsone; Humans; Hydroxylamine; Hydroxylamines; Indomethacin; Leukocytes, Mononuclear; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Chemotactic response of human neutrophils to N-acetyl chitohexaose in vitro.
Topics: Adult; Aspirin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Synergism; Humans; Indomethacin; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligosaccharides; Phospholipases A; Phospholipases A2; Prostaglandins E; Prostaglandins F | 1988 |
Increased airways responsiveness to histamine induced by platelet activating factor in the guinea-pig: possible role of lipoxygenase metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Atropine Derivatives; Bronchi; Female; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase; Male; Masoprocol; Platelet Activating Factor; Pyrazoles; Vagotomy | 1988 |
Mobilization of arachidonic acid in collagen-stimulated human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Membrane Lipids; Phosphatidic Acids; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyrazoles | 1988 |
Protective effects of the antianginal agent nicorandil on arachidonate-induced sudden death in rats: comparison with several antianginal agents and cyclooxygenase inhibitors.
Topics: Angina Pectoris; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Death, Sudden; Diltiazem; Indomethacin; Male; Mice; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Vasodilator Agents | 1985 |
The effect of fosfosal and acetylsalicylic acid on leukocyte migration and PGE2 concentration in experimentally induced acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Migration Inhibition; Dinoprostone; Indomethacin; Inflammation; Male; Neutrophils; Organophosphates; Organophosphorus Compounds; Prostaglandins E; Rats; Rats, Inbred Strains | 1988 |
Indomethacin-induced gastric antral ulcers in hamsters.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal; Gastric Acid; Indomethacin; Injections, Subcutaneous; Male; Mesocricetus; Omeprazole; Peptic Ulcer Perforation; Prostaglandins E; Stomach Ulcer; Time Factors | 1988 |
Effects of increased pulmonary vascular tone on gas exchange in canine oleic acid pulmonary edema.
Topics: Almitrine; Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Indomethacin; Lung; Oleic Acid; Oleic Acids; Oxygen; Piperazines; Pulmonary Edema; Pulmonary Gas Exchange; Vascular Resistance | 1988 |
Evidence implicating protein kinase C in exocytosis from electropermeabilized bovine chromaffin cells.
Topics: Animals; Aspirin; Binding, Competitive; Calcium; Catecholamines; Cations, Divalent; Cattle; Cell Membrane Permeability; Chromaffin System; Diglycerides; Electric Stimulation; Exocytosis; In Vitro Techniques; Indomethacin; Inositol; Kinetics; Molecular Weight; Phorbol Esters; Protein Kinase C; Substrate Specificity | 1988 |
Differential effects of oral administrations to human volunteers of acetylsalicylic acid, sodium salicylate and indomethacin on 12-hydroxyeicosatetraenoic acid formation by stimulated platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Administration, Oral; Adult; Aspirin; Blood Platelets; Drug Administration Schedule; Female; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Male; Platelet Aggregation; Sodium Salicylate; Thromboxane B2 | 1988 |
Pharmacological studies of lappaconitine. Analgesic activities.
Topics: Aconitine; Aconitum; Analgesics; Animals; Aspirin; Dose-Response Relationship, Drug; Hot Temperature; Indomethacin; Male; Mice; Morphine; Pain; Pressure; Rats; Rats, Inbred Strains; Reaction Time; Reflex | 1988 |
Effect of indomethacin, aspirin, and acetaminophen on in vitro antiviral and antiproliferative activities of recombinant human interferon-alpha 2a.
Topics: Acetaminophen; Animals; Antiviral Agents; Aspirin; Cell Division; Cell Line; Drug Interactions; Humans; Indomethacin; Interferon alpha-2; Interferon Type I; Interferon-alpha; Mice; Recombinant Proteins; Tumor Cells, Cultured | 1988 |
Improving micrograft patency.
Topics: Animals; Aspirin; Blood Vessel Prosthesis; Carotid Artery, Internal; Female; Humans; Ibuprofen; Indomethacin; Jugular Veins; Microsurgery; Platelet Aggregation Inhibitors; Polytetrafluoroethylene; Rats; Rats, Inbred Strains; Umbilical Veins; Vascular Patency | 1988 |
Inhibition of postpyrogenic increase of phagocytic and killing activity of neutrophils by nonsteroid antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Fever; In Vitro Techniques; Indomethacin; Killer Cells, Natural; Male; Mefenamic Acid; Neutrophils; Phagocytosis; Rabbits | 1988 |
Further studies on the role of the adrenals in the capsaicin-sensitive "gastric defence mechanism".
Topics: Adrenal Glands; Animals; Aspirin; Capsaicin; Drug Synergism; Ethanol; Indomethacin; Rats; Rats, Inbred Strains; Stomach Ulcer | 1988 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Male; Nifedipine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Lymphocytes infiltration induces dysfunction in autoimmune myocarditis: role of SRS-A.
Topics: Animals; Aspirin; Autoimmune Diseases; B-Lymphocytes; Dithizone; Indomethacin; Male; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocarditis; Myocardium; SRS-A; T-Lymphocytes | 1988 |
Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cycloheximide; Dexamethasone; Epidermal Growth Factor; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Naproxen; Steroids; Stomach | 1988 |
Time-course study of gastric damages in rats by anti-inflammatory drugs using a gastroscope and its quantification.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Fenoprofen; Gastric Mucosa; Gastrointestinal Hemorrhage; Indomethacin; Male; Mefenamic Acid; Peptic Ulcer; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Cell Division; Cells, Cultured; Dinoprost; Dinoprostone; Growth Inhibitors; Immunologic Techniques; Indomethacin; Interleukin-1; Mitogens; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandins; Prostaglandins E; Prostaglandins F; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Recombinant Proteins | 1988 |
Pharmacological protection against the toxicity of N-methyl-D-aspartate in immature rat cerebellar slices.
Topics: Animals; Aspartic Acid; Aspirin; Calcium Channel Blockers; Cerebellum; Female; In Vitro Techniques; Indomethacin; Kynurenic Acid; Leupeptins; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Taurine | 1987 |
A direct in vivo comparison of the inflammatory properties of human C5a and C5a des Arg in human skin.
Topics: Aspirin; Biopsy, Needle; Complement C5; Complement C5a; Complement C5a, des-Arginine; Dermatitis; Humans; Indomethacin; Piroxicam; Skin; Skin Tests | 1988 |
Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus.
Topics: Animals; Antibodies, Viral; Antibody Formation; Aspirin; Female; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Influenza A virus; Killer Cells, Natural; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Prostaglandins A, Synthetic; Virus Replication | 1988 |
Effects of tiaprofenic acid and other NSAIDs on proteoglycan metabolism in articular cartilage explants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage, Articular; Culture Techniques; Dogs; Electrophoresis, Polyacrylamide Gel; Indomethacin; Naproxen; Propionates; Proteoglycans; Sulfur Radioisotopes | 1988 |
Effect of some non-steroidal anti-inflammatory drugs on ouabain-induced arrhythmias in guinea-pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aspirin; Blood Pressure; Female; Guinea Pigs; Heart Rate; Hemodynamics; Indomethacin; Ketoprofen; Male; Ouabain | 1988 |
Effects of non-steroidal anti-inflammatory drugs on rat gastric mucosal leukotriene C4 and prostanoid release: relation to ethanol-induced injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Eicosanoic Acids; Ethanol; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains; Salicylates; SRS-A | 1988 |
Protective action of SCH 12223 against experimentally induced gastric and intestinal lesions.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; Injections, Intravenous; Intestinal Diseases; Male; Naphthyridines; Rats; Reserpine; Stomach Ulcer | 1988 |
Phosphatidylcholine peroxidation induced by Cu(II) and some Cu(II) complexes.
Topics: Ascorbic Acid; Aspirin; Cimetidine; Copper; Glycine; Indomethacin; Lipid Peroxides; NAD; Oxidation-Reduction; Phosphatidylcholines | 1988 |
[Differential effects of non-steroidal anti-inflammatory drugs on cathepsins D and E from rat spleen].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cathepsin D; Cathepsin E; Cathepsins; Flufenamic Acid; Hydrogen-Ion Concentration; Indomethacin; Isomerism; Rats; Sodium Salicylate; Spleen | 1988 |
Increased in vitro bone resorption by monocytes in the hyper-immunoglobulin E syndrome.
Topics: Aspirin; Bone Resorption; Child; Child, Preschool; Dinoprostone; Female; Humans; Hydroxyproline; Hypergammaglobulinemia; Immunoglobulin E; In Vitro Techniques; Indomethacin; Male; Monocytes; Osteoporosis; Prostaglandins E | 1988 |
[Effect of treatment with 15/R/15-methyl derivative of prostaglandin E2 on aspirin- and indomethacin-induced damage of the mucous membrane of the upper digestive tract in rheumatoid arthritis patients].
Topics: Adult; Aged; Arbaprostil; Arthritis, Rheumatoid; Aspirin; Female; Gastric Mucosa; Gastritis; Humans; Indomethacin; Male; Middle Aged; Prostaglandins E, Synthetic | 1987 |
Renal responses to angiotensin II in conscious dogs: effects of aspirin and indomethacin.
Topics: Anesthesia; Angiotensin II; Animals; Aspirin; Blood Pressure; Dogs; Electrolytes; Glomerular Filtration Rate; Indomethacin; Kidney; Renal Circulation; Urodynamics | 1987 |
[Chronic arthritis. Round table].
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Autoantibodies; Child; Humans; Indomethacin; Naproxen; Penicillamine; Rheumatoid Factor; Tolmetin | 1987 |
Analgesic activity following combined oral administration of flupirtine maleate and peripherally acting analgesics in mice and rats.
Topics: Acetaminophen; Administration, Oral; Aminopyridines; Analgesics; Animals; Aspirin; Drug Evaluation, Preclinical; Drug Synergism; Ibuprofen; Indomethacin; Male; Mice; Mice, Inbred Strains; Pain Measurement; Peripheral Nerves; Rats; Rats, Inbred Strains | 1987 |
Effect of non-steroidal anti-inflammatory drugs on fertility of male rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dinoprostone; Fertility; Indomethacin; Kinetics; Male; Naproxen; Phenylbutazone; Prostaglandins E; Rats; Rats, Inbred Strains; Semen | 1986 |
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin | 1986 |
Endogenous prostaglandins in gastric alkaline response in the rat stomach after damage.
Topics: 16,16-Dimethylprostaglandin E2; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bicarbonates; Cimetidine; Dinoprostone; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Membrane Potentials; Prostaglandins; Prostaglandins E; Rats; Taurocholic Acid | 1986 |
Phospholipids, prostaglandin E2, and proteolysis in denervated muscle.
Topics: Animals; Aspirin; Cardiolipins; Cycloheximide; Dinoprostone; Indomethacin; Lysophosphatidylcholines; Male; Muscle Denervation; Muscle Proteins; Muscles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Sphingomyelins; Tyrosine | 1986 |
The effects of metamizol on prostaglandin synthesis in man.
Topics: Alprostadil; Aminopyrine; Aspirin; Collagen; Dinoprostone; Dipyrone; Gastric Juice; Gastric Mucosa; Humans; In Vitro Techniques; Indomethacin; Kidney; Kinetics; Platelet Aggregation; Prostaglandins; Prostaglandins E; Thromboxanes | 1986 |
Discharge characteristics of receptors with fine afferents from normal and inflamed joints: influence of analgesics and prostaglandins.
Topics: Action Potentials; Afferent Pathways; Alprostadil; Animals; Arthritis; Aspirin; Cats; Dinoprostone; Indomethacin; Inflammation; Knee Joint; Movement; Neural Conduction; Nociceptors; Pain; Prostaglandins E | 1986 |
Effects of acetylsalicylic acid and indomethacin on single groups III and IV sensory units from acutely inflamed joints.
Topics: Afferent Pathways; Animals; Aspirin; Cats; Dinoprostone; Electrophysiology; Female; Indomethacin; Inflammation; Knee Joint; Male; Movement; Neural Conduction; Prostaglandins E | 1986 |
Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Humans; Ibuprofen; Indomethacin; Intestine, Small; Permeability; Prostaglandins E; Ranitidine | 1986 |
Irritative and protective activity of mild irritants in rat stomach.
Topics: Animals; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Membrane Potentials; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium Salicylate; Taurocholic Acid | 1987 |
In vitro effects of serotonin and prostaglandins on release of eggs from the ovary of the scallop, Patinopecten yessoensis.
Topics: Animals; Aspirin; Dinoprost; Dinoprostone; Dopamine; Female; Indomethacin; Methysergide; Mollusca; Ovary; Ovum; Prostaglandins E; Prostaglandins F; Serotonin; Sulpiride | 1987 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Serotonin; SRS-A; Thromboxane B2; Trachea | 1987 |
Production of an immune suppressor factor by Marek's disease lymphoblastoid cell lines.
Topics: Animals; Aspirin; Cell Line; Chickens; Dinoprostone; Indomethacin; Lymphocyte Activation; Lymphocytes; Marek Disease; Mitogens; Prostaglandins E; Spleen; Suppressor Factors, Immunologic | 1987 |
Relationship between plasma PGE2 level and changes in hemoglobin proportions during bleeding-induced anemia in adult rats.
Topics: Anemia; Animals; Aspirin; Dinoprostone; Erythropoiesis; Gene Expression Regulation; Hemoglobins; Hemorrhage; Indomethacin; Prostaglandins E; Rats; Rats, Inbred Strains | 1987 |
Serpiginous gastric erosions caused by aspirin and other nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Gastric Mucosa; Gastritis; Humans; Indomethacin; Naproxen; Radiography | 1986 |
Effect of simulated systemic administration of aspirin, salicylate, and indomethacin on amphibian gastric mucosa.
Topics: 16,16-Dimethylprostaglandin E2; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Dinoprostone; Electrophysiology; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; Indomethacin; Metiamide; Prostaglandins; Prostaglandins E; Prostaglandins F; Rana catesbeiana; Sodium Salicylate; Time Factors | 1986 |
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Gastric Acid; Granuloma; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mice; Phenylbutazone; Piroxicam; Prostaglandins; Pyrazoles; Pyrimidines; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiazines | 1986 |
[The analgesic and antipyretic effects of a non-steroidal antiinflammatory agent, EB-382, in experimental animals].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Ibuprofen; Indomethacin; Mice; Morphine; Pain; Phenylbutazone; Propionates; Rats; Rats, Inbred Strains | 1986 |
Piroxicam and gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Utilization; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Norway; Piroxicam; Prospective Studies | 1986 |
Diacylglycerol causes Ca release from the platelet dense tubular system: comparisons with Ca release caused by inositol 1,4,5-triphosphate.
Topics: Adenosine Triphosphate; Aspirin; Blood Platelets; Calcium; Diglycerides; Dose-Response Relationship, Drug; Glycerides; Humans; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Membranes; Lysophospholipids; Phosphatidic Acids; Platelet Aggregation; Saponins; Serotonin; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1987 |
Comparative studies on the gastrointestinal lesions caused by several nonsteroidal anti-inflammatory agents in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Feces; Gastric Mucosa; Gastrointestinal Hemorrhage; Ibuprofen; Indomethacin; Intestinal Mucosa; Oxaprozin; Phenylpropionates; Propionates; Rats | 1987 |
An in situ experimental model in rabbits for the study of rectal absorption.
Topics: Animals; Aspirin; Indomethacin; Insulin; Intestinal Absorption; Kinetics; Male; Rabbits; Rectum; Salicylates; Salicylic Acid; Suppositories; Time Factors | 1986 |
Cardiovascular actions of dihydralazine as modified by dietary linoleic acid.
Topics: Animals; Aorta, Abdominal; Aspirin; Blood Pressure; Dietary Fats; Dihydralazine; Epoprostenol; Fatty Acids; Female; Hydralazine; In Vitro Techniques; Indomethacin; Kidney; Linoleic Acid; Linoleic Acids; Male; Phospholipids; Pregnancy; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity | 1986 |
Effects of low doses of aspirin and dipyridamole on platelet aggregation in the dog coronary artery.
Topics: Animals; Aspirin; Coronary Circulation; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Female; Indomethacin; Male; Platelet Aggregation; Thromboxane B2 | 1987 |
Effects of insulin and prior exercise on prostaglandin release from perfused rat muscle. Evidence that prostaglandins do not mediate changes in glucose uptake.
Topics: Aminoisobutyric Acids; Animals; Aspirin; Glucose; Indomethacin; Insulin; Male; Muscles; Perfusion; Physical Exertion; Prostaglandins; Rats; Rats, Inbred Strains | 1986 |
Hormonal regulation of myoblast proliferation and myotube production in vivo: influence of prostaglandins.
Topics: Alprostadil; Animals; Aspirin; Cell Division; Cell Nucleus; Chick Embryo; Indomethacin; Mitosis; Muscles | 1987 |
Cytoprotective agents in experimental small bowel volvulus.
Topics: Alprostadil; Animals; Aspirin; Ephedrine; Ibuprofen; Indomethacin; Intestinal Obstruction; Intestine, Small; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1987 |
Failure of chronic aspirin treatment to inhibit urinary prostaglandin excretion in spontaneously hypertensive rats: comparison with indomethacin and flurbiprofen.
Topics: Animals; Aspirin; Drug Administration Schedule; Flurbiprofen; Hypertension; Indomethacin; Kidney; Male; Propionates; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
An investigation of the angry back syndrome using Trafuril.
Topics: Aspirin; Erythema; False Positive Reactions; Furans; Humans; Indomethacin; Nicotinic Acids; Patch Tests; Skin; Skin Tests | 1987 |
Effect of indomethacin and acetylsalicylic acid (ASA) on peroxidase activity of gastric mucosa of rat.
Topics: Animals; Aspirin; Female; Gastric Mucosa; Histocytochemistry; Indomethacin; Male; Peroxidases; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Aspirin, indomethacin, and tartrazine increase carotid-sinus-nerve activity and arterial blood pressure in guinea pigs.
Topics: Animals; Aspirin; Azo Compounds; Blood Pressure; Carotid Sinus; Female; Guinea Pigs; Indomethacin; Neurons; Phenylephrine; Stimulation, Chemical; Tartrazine | 1987 |
Tolerance to acetylsalicylic acid (ASA) induced in ASA-sensitive asthmatics does not depend on initial adverse reaction.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Drug Tolerance; Female; Humans; Indomethacin; Male; Middle Aged | 1987 |
[The significance of renal prostaglandins for kidney function in early childhood].
Topics: Angiotensin II; Aspirin; Child, Preschool; Creatinine; Ductus Arteriosus, Patent; Glomerular Filtration Rate; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Kidney Diseases; Kidney Function Tests; Oliguria; Prostaglandins; Prostaglandins E; Renal Circulation; Renin-Angiotensin System; Vasopressins; Water-Electrolyte Balance | 1987 |
Efficacy of sucralfate in preventing peptic ulceration induced by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Indomethacin; Male; Peptic Ulcer; Rats; Stomach Ulcer; Sucralfate | 1987 |
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombocytopenia | 1987 |
Effects of prostaglandin biosynthesis inhibitors and ouabain on duodenal mucosa and HCO3- secretion in rats.
Topics: Animals; Aspirin; Bicarbonates; Drug Interactions; Duodenum; Gastric Mucosa; Histamine; Indomethacin; Intestinal Mucosa; Male; Ouabain; Prostaglandin Antagonists; Quinacrine; Rats | 1987 |
Studies on the gastroulcerogenic effects of pylorus ligation, hypothermic restraint stress, aspirin, indomethacin and reserpine in morphine dependent rats.
Topics: Animals; Aspirin; Gastric Acid; Hypothermia; Indomethacin; Ligation; Male; Morphine Dependence; Pylorus; Rats; Reserpine; Restraint, Physical; Stomach Ulcer | 1987 |
Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases.
Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Female; Glucocorticoids; Humans; Indomethacin; Joints; Male; Middle Aged; Prognosis | 1986 |
The effect of acetylsalicylic acid and indomethacin on the catecholamine- and oxytocin-induced contractility and prostaglandin (6-keto-PGF1 alpha, PGF2 alpha)-production of human pregnant myometrial strips.
Topics: Aspirin; Epinephrine; Female; Humans; In Vitro Techniques; Indomethacin; Myometrium; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Prostaglandins F; Uterine Contraction | 1987 |
Inhibition of in vitro lysozyme release from human granulocytes and monocytes by non-steroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Granulocytes; Humans; In Vitro Techniques; Indomethacin; Monocytes; Muramidase; Naproxen | 1987 |
Chronic paroxysmal hemicrania: the first possible bilateral case.
Topics: Aged; Aspirin; Chronic Disease; Female; Humans; Indomethacin; Migraine Disorders | 1986 |
Determination of acid-neutralizing capacity in rat duodenum. Influences of 16,16-dimethyl prostaglandin E2 and nonsteroidal antiinflammatory drugs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Inflammatory Agents; Aspirin; Bicarbonates; Duodenum; Gastric Acid; Gastric Acidity Determination; Hydrogen-Ion Concentration; Indomethacin; Male; Prostaglandins E, Synthetic; Quinacrine; Rats; Rats, Inbred Strains | 1986 |
Dissociation between antinociceptive and anti-inflammatory effects of acetylsalicylic acid and indomethacin in the formalin test.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indomethacin; Inflammation; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Nociceptors | 1986 |
Mechanisms of cell association of chloroquine to leucocytes.
Topics: Aspirin; Cell Survival; Chloroquine; Humans; Hydrogen-Ion Concentration; Indomethacin; Leukocytes; Mathematics; Neutrophils; Salicylates; Salicylic Acid; Temperature; Time Factors | 1986 |
[Development of aspirin tolerance in hypersensitive persons. I. Methods of development of tolerance, aspirin refraction time and cross tolerance to other drugs].
Topics: Antipyrine; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; Indomethacin; Tachyphylaxis; Urticaria | 1986 |
[Importance of prostaglandins and cyclic nucleotides in altering thrombocyte aggregation induced by thyroxine].
Topics: Adenosine Diphosphate; Animals; Aspirin; Drug Interactions; Female; Indomethacin; Male; Nucleotides, Cyclic; Platelet Aggregation; Prostaglandins, Synthetic; Rabbits; Serotonin; Thyroxine; Time Factors | 1986 |
Antiulcer and gastroprotective effects of solon, a synthetic flavonoid derivative of sophoradin. Role of endogenous prostaglandins.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Chalcone; Chalcones; Ethanol; Female; Gastric Juice; Indomethacin; Male; Propiophenones; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1986 |
The effects of aspirin, indomethacin and their copper complexes on phospholipase activity and on lipid peroxidation in rat liver microsomes.
Topics: Animals; Aspirin; Chelating Agents; Copper; Indomethacin; Lipid Peroxides; Male; Microsomes, Liver; NADP; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Rats; Rats, Inbred Strains | 1986 |
Indomethacin and acetylsalicylic acid reduce intrapulmonary shunt in experimental pneumococcal pneumonia.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Dogs; Indomethacin; Lung; Organ Size; Oxygen; Pneumonia, Pneumococcal; Pulmonary Circulation; Pulmonary Gas Exchange | 1986 |
A possible role for endogenous prostaglandins in the electrophysiological effects of acetylstrophanthidin on isolated canine ventricular tissues.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arrhythmias, Cardiac; Aspirin; Cardiac Pacing, Artificial; Dogs; Female; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Papillary Muscles; Purkinje Fibers; Strophanthidin; Time Factors; Ventricular Function | 1986 |
Prostanoid inhibition potentiates vasoconstrictor response to acetylcholine in dog lung.
Topics: Acetylcholine; Animals; Aspirin; Blood Pressure; Dogs; Female; Indomethacin; Male; Prostaglandins; Pulmonary Circulation; Receptors, Muscarinic; Theophylline; Vascular Resistance; Vasoconstriction | 1986 |
Ulcerogenic and antiulcerogenic effects of a new antiinflammatory drug, the gamma-lactone-N-ethyl derivative of 6-[1S-(3S,4-dihydro-8-hydroxy-1H-2-benzo- pyran-1-one-3-yl)-3-methylbutylamino]-4S,5S-dihydroxy-6-oxo-3S- ammoniohexanoate, on gastrointestinal
Topics: Animals; Anti-Ulcer Agents; Aspirin; Coumarins; Gastrointestinal Motility; Indomethacin; Isocoumarins; Male; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
[Treatment of dysmenorrhea].
Topics: Adolescent; Adult; Age Factors; Aspirin; Dysmenorrhea; Female; Humans; Indomethacin | 1986 |
[Chronic paroxysmal migraine. A review and presentation of 4 new cases].
Topics: Aspirin; Chronic Disease; Diagnosis, Differential; Female; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders | 1986 |
Regulation of increase in anastomotic blood flow following pulmonary arterial occlusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterial Occlusive Diseases; Arteriovenous Anastomosis; Aspirin; Bronchi; Dogs; Indomethacin; Pulmonary Artery; Regional Blood Flow; Thromboxane B2 | 1985 |
Effect of vegetable banana powder on changes induced by ulcerogenic agents in dissolved mucosubstances of gastric juice.
Topics: Animals; Aspirin; Carbohydrates; Female; Fruit; Gastric Juice; Indomethacin; Male; Peptic Ulcer; Phenylbutazone; Prednisolone; Proteins; Rats | 1985 |
Prostaglandins or prostaglandin like substances are implicated in normal growth and development in oomycetes.
Topics: Alprostadil; Aspirin; Dinoprost; Dose-Response Relationship, Drug; Fatty Acids; Fungi; Indomethacin; Oomycetes; Prostaglandins; Prostaglandins E; Prostaglandins F | 1985 |
[Prostaglandin studies in normal subjects and in post-myocardial infarct patients].
Topics: Adult; Aspirin; Child; Dinoprost; Female; Humans; Indomethacin; Male; Myocardial Infarction; Physical Exertion; Prostaglandins F; Renin-Angiotensin System; Sulfinpyrazone | 1985 |
Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection.
Topics: Animals; Aspirin; Dinoprostone; Disease Susceptibility; Fasting; Gastric Mucosa; Indomethacin; Injections, Subcutaneous; Mice; Mice, Mutant Strains; Prostaglandins E; Pyloric Antrum; Stomach Ulcer; Stress, Physiological | 1985 |
Gastric mucosal protection by spizofurone.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Dinoprostone; Electrolytes; Ethanol; Gastric Mucosa; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1985 |
Rat's vessel wall generates an antiaggregatory substance independent of prostacyclin production.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Aspirin; Catechols; Endothelium; Female; Humans; In Vitro Techniques; Indomethacin; Masoprocol; Platelet Aggregation; Rats | 1985 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
Ulcer formation and cytoprotection by acetazolamide.
Topics: 16,16-Dimethylprostaglandin E2; Acetazolamide; Animals; Aspirin; Dinoprostone; Ethanol; Female; Gastric Mucosa; Indomethacin; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer; Time Factors | 1985 |
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cimetidine; Dogs; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Indomethacin; Male; Phenylpropionates; Pylorus; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Stomach Ulcer; Stress, Physiological; Tranexamic Acid | 1985 |
Thymus cell migration in a prostaglandin-mediated system.
Topics: Animals; Aspirin; B-Lymphocytes; Cell Movement; Cell Separation; Cytophotometry; DNA Nucleotidylexotransferase; Flow Cytometry; Idoxuridine; Indomethacin; Male; Mice; Prostaglandins; Spleen; T-Lymphocytes; Thymectomy; Thymus Gland | 1985 |
The influence of total hip replacement on hip pain and the use of analgesics.
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Dextropropoxyphene; Female; Hip Prosthesis; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Pain; Pain, Postoperative | 1985 |
Endogenous prostaglandins modulate histamine-induced contraction in canine tracheal smooth muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Chromatography, High Pressure Liquid; Dogs; Epoprostenol; Histamine; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins; Radioimmunoassay; Trachea | 1985 |
Acetyl-salicylic acid impairs insulin-mediated glucose utilization and reduces insulin clearance in healthy and non-insulin-dependent diabetic man.
Topics: Adult; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Indomethacin; Injections, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Reference Values | 1985 |
Migration of isolated rabbit lymphocytes in the course of pharmacological inhibition of pyrogenic fever.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Escherichia coli; Fever; Indomethacin; Injections, Intravenous; Lipopolysaccharides; Lymphocytes; Male; Mefenamic Acid; Rabbits | 1985 |
The effects of cyclooxygenase and lipoxygenase inhibitors on the collagen abnormalities of diabetic rats.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Female; Indomethacin; Lipoxygenase Inhibitors; Naproxen; Rats; Rats, Inbred Strains | 1985 |
Enhancement of the antiproliferative activity of human interferon by polyamine depletion.
Topics: Aspirin; Cell Division; Cell Line; Doxorubicin; Drug Synergism; Eflornithine; Humans; Indomethacin; Interferon Type I; Neoplasms; Ornithine; Polyamines; Putrescine; Tumor Stem Cell Assay | 1985 |
Formation of 11-hydroxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid in human umbilical arteries is catalyzed by cyclooxygenase.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Infant, Newborn; Masoprocol; Prostaglandin-Endoperoxide Synthases; Subcellular Fractions; Umbilical Arteries | 1985 |
Comparative in vivo inhibitory effects of nonsteroidal anti-inflammatory agents on prostaglandin synthesis in rabbit ocular tissues.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Conjunctiva; Dinoprostone; Flurbiprofen; Indomethacin; Injections, Intraperitoneal; Prostaglandins E; Rabbits; Uvea | 1985 |
[Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences].
Topics: Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Male; Prostaglandin Endoperoxides; Sodium Salicylate | 1985 |
Stimulation of calcium uptake in rat calvaria by prostacyclin.
Topics: Animals; Aspirin; Calcium; Cartilage; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Indomethacin; Rats | 1985 |
Inhibition of platelet adhesion to aortic subendothelium by indomethacin--an effect unrelated to inhibition of arachidonic acid metabolism.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Endothelium; In Vitro Techniques; Indomethacin; Platelet Adhesiveness; Rabbits | 1985 |
Differential inhibition of platelet thromboxane and lung prostacyclin production by sulphinpyrazone, acetylsalicylic acid and indomethacin by human tissues in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Humans; In Vitro Techniques; Indomethacin; Lung; Sulfinpyrazone; Thromboxane A2; Thromboxane B2 | 1985 |
Prostanoid synthesis in peripheral nerve.
Topics: Animals; Anura; Arachidonic Acid; Arachidonic Acids; Aspirin; Chromatography, Thin Layer; Electric Stimulation; Glutathione; Indomethacin; Peripheral Nerves; Prostaglandins; Rats; Sciatic Nerve | 1985 |
Prostaglandin E2 and muscle protein turnover in Pseudomonas aeruginosa sepsis.
Topics: Animals; Aspirin; Cycloheximide; Dinoprostone; Indomethacin; Male; Muscle Proteins; Muscles; Prostaglandins E; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Normalization of monocyte candidacidal deficiency by cyclooxygenase inhibitors in Hodgkin's disease.
Topics: Adolescent; Adult; Aspirin; Candida; Cells, Cultured; Child; Child, Preschool; Cyclooxygenase Inhibitors; Dinoprostone; Female; Hodgkin Disease; Humans; Indomethacin; Macrophage Activation; Male; Middle Aged; Monocytes; Phagocytosis; Prostaglandins E | 1985 |
Indomethacin and salicylate modulate effect of insulin on glucose kinetics in dogs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Glucose; Dogs; Drug Interactions; Female; Gluconeogenesis; Glucose; Indomethacin; Insulin; Kinetics; Liver; Prostaglandin Antagonists; Prostaglandins; Salicylates; Salicylic Acid; Time Factors | 1985 |
The influence of cyclo-oxygenase inhibitors on the cardiovascular effects of hydralazine in rats.
Topics: Animals; Aspirin; Blood Pressure; Body Temperature; Cyclooxygenase Inhibitors; Heart Rate; Hemodynamics; Hydralazine; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains; Vasodilation | 1985 |
Morphological alterations in cultured endothelial cells induced by arachidonic acid.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; Dinoprostone; Dose-Response Relationship, Drug; Endothelium; Fatty Acids; Female; Ibuprofen; Indomethacin; Kinetics; Male; Phospholipids; Prostaglandins E; Pulmonary Artery; SRS-A; Time Factors | 1985 |
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniques; Indomethacin; Leupeptins; Lysosomes; Muscles; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Proteins; Quinacrine; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Dinoprost; Dinoprostone; Epoprostenol; Guinea Pigs; Ibuprofen; Indomethacin; Ligation; Male; Ouabain; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Time Factors | 1985 |
Suppression of cellular immunity to Listeria monocytogenes by activated macrophages: mediation by prostaglandins.
Topics: Alprostadil; Animals; Aspirin; Cell Adhesion; Female; Immunity, Cellular; Immunosuppression Therapy; Indomethacin; Listeria monocytogenes; Listeriosis; Macrophage Activation; Macrophages; Mice; Prostaglandins; Prostaglandins E | 1985 |
Differential effects of aspirin and indomethacin on platelet and leukocyte thromboxane A2 formation.
Topics: Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Thromboxanes | 1985 |
Modulation by drugs of leukotriene and prostaglandin production from mouse peritoneal macrophages.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetaminophen; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Dinoprostone; Dipyrone; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins E; Pyrazoles; Pyrazolones; SRS-A | 1985 |
Polymorphonuclear leukocyte: arachidonate edema.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Catalase; Catechols; Endothelium; Epoprostenol; Humans; In Vitro Techniques; Indomethacin; Masoprocol; Neutrophils; Papaverine; Perfusion; Physiology; Pulmonary Edema; Rabbits; Serum Albumin, Bovine | 1985 |
Dopamine-induced potentiation of the contractile response to arachidonic acid in guinea-pig aorta.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Corticosterone; Dopamine; Drug Synergism; Guinea Pigs; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine | 1985 |
Interaction of non-steroidal anti-inflammatory drugs on platelet cyclo-oxygenase and lipoxygenase activity.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Kinetics; Lipoxygenase; Models, Biological; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone | 1985 |
Cardiovascular changes due to premature closure of the ductus arteriosus: a mathematical model.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Ductus Arteriosus; Hemodynamics; Indomethacin; Models, Cardiovascular; Pulmonary Circulation; Sheep; Vascular Resistance | 1985 |
Prostaglandin-related bone resorption in cultured neonatal mouse calvaria: evaluation of biopotency of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Bone Resorption; Cells, Cultured; Indomethacin; Mice; Mice, Inbred Strains; Parathyroid Hormone; Prostaglandins; Thrombin | 1985 |
In vivo modulation of leukotaxis by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Chemotaxis, Leukocyte; Female; Flurbiprofen; Ibuprofen; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Rabbits | 1985 |
Liberation of prostaglandin-like substances from the isolated coronary artery in presence of angiotensin and of 4-methylesculetin.
Topics: Angiotensin II; Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Drug Interactions; In Vitro Techniques; Indomethacin; Lysine; Muscle, Smooth, Vascular; Prostaglandins; Scopoletin; Umbelliferones | 1985 |
Structural damage and changes in eicosanoid metabolites in the gastric mucosa of rats and pigs induced by anti-inflammatory drugs of varying ulcerogenicity.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diflunisal; Gastric Mucosa; Indomethacin; Membrane Potentials; Microscopy, Electron; Phenylacetates; Piroxicam; Propionates; Prostaglandins; Rats; Stomach Ulcer; Sulindac; Swine; Thiazines | 1986 |
European experience with flurbiprofen. A new analgesic/anti-inflammatory agent.
Topics: Aspirin; Drug Evaluation; Europe; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Propionates | 1986 |
Effect of high doses of aspirin on pulmonary hemodynamics and lung water.
Topics: Animals; Aspirin; Blood Pressure; Blood Volume; Body Water; Dogs; Female; Hemodynamics; Indomethacin; Lung; Male; Meclofenamic Acid; Pulmonary Circulation | 1985 |
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperkalemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Nephritis, Interstitial | 1985 |
Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia.
Topics: Adult; Aged; Analgesics; Arteries; Arterioles; Arteritis; Aspirin; Blood Platelets; Erythromelalgia; Female; Humans; Indomethacin; Male; Malondialdehyde; Middle Aged; Polycythemia Vera; Skin; Thrombocytosis; Thrombosis | 1985 |
Antihemostatic and antithrombotic effects of capsaicin in comparison with aspirin and indomethacin.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Capsaicin; Hemostasis; Indomethacin; Mice; Mice, Inbred ICR; Platelet Aggregation; Thromboembolism; Thrombosis | 1985 |
Airway hysteresis in normal subjects and individuals with chronic airflow obstruction.
Topics: Adult; Airway Resistance; Ascorbic Acid; Aspirin; Bronchi; Female; Humans; Indomethacin; Lung Compliance; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Ventilation; Time Factors; Total Lung Capacity | 1985 |
Lack of effect of prostaglandin inhibition on calcium excretion in normal volunteers.
Topics: Adult; Aspirin; Calcium; Creatinine; Humans; Indomethacin; Ketoprofen; Male; Prostaglandin Antagonists; Sodium | 1985 |
[Acetylsalicylic acid and indomethacin in the treatment of idiopathic orthostatic hypotension and Shy-Drager's syndrome].
Topics: Aged; Aspirin; Autonomic Nervous System Diseases; Female; Humans; Hypotension, Orthostatic; Indomethacin; Male; Shy-Drager Syndrome | 1985 |
Aspirin inhibition of 1 alpha-hydroxyvitamin D3 or parathyroid hormone induced hypercalcemia in vivo in rats. A mechanism independent of prostaglandin biosynthesis inhibition.
Topics: Animals; Aspirin; Calcium; Hydroxycholecalciferols; Indomethacin; Intestinal Absorption; Male; Parathyroid Hormone; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Inbred Strains | 1985 |
In vitro comparison of the efficacy of cyclooxygenase inhibitors on the adult versus neonatal platelet.
Topics: Adult; Aspirin; Blood Platelets; Female; Fetal Blood; Humans; Indomethacin; Infant, Newborn; Male; Thrombin; Thromboxane B2 | 1985 |
Effects of some anti-inflammatory drugs on 12 blood constituents: protocol for the study of in vivo effects of drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Chemical Analysis; Blood Urea Nitrogen; Cholesterol; Creatinine; Diclofenac; Humans; Ibuprofen; Indomethacin; Iron; Ketoprofen; Prospective Studies; Retrospective Studies; Serum Albumin; Time Factors; Triglycerides; Uric Acid | 1985 |
Sodium-salicylate in contrast with acetylsalicylic acid prevents gastric antral and intestinal ulcers produced by indomethacin in the refed rat.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Eating; Female; Indomethacin; Intestinal Diseases; Pyloric Antrum; Rats; Rats, Inbred Strains; Sodium Salicylate; Stomach Ulcer; Ulcer | 1985 |
Effect of some anti-inflammatory drugs on FMLP-induced chemotaxis and random migration of rat polymorphonuclear leucocytes.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; In Vitro Techniques; Indomethacin; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Inbred Strains | 1985 |
Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms.
Topics: Acetaminophen; Alcohol Drinking; Analgesics; Anti-Inflammatory Agents; Aspirin; Chronic Disease; Female; Humans; Indomethacin; Male; Risk; Smoking; Stomach Ulcer | 1985 |
Functional and biochemical characterization of immunologically derived equine platelet-activating factor.
Topics: Animals; Antigens, Helminth; Ascaris; Aspirin; Blood Platelets; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Horses; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Leukocytes; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1985 |
[Collapse of the blood-aqueous humor barrier following laser injury--preventive pharmacotherapy with prostaglandin inhibitors].
Topics: Animals; Aqueous Humor; Aspirin; Blood Proteins; Capillary Permeability; Dexamethasone; Dose-Response Relationship, Drug; Indomethacin; Iris; Laser Therapy; Lasers; Prostaglandin Antagonists; Rabbits | 1985 |
Inhibition of prostaglandin synthesis produces a muscular dystrophy-like myopathy.
Topics: Alprostadil; Animals; Aspirin; Chick Embryo; Indomethacin; Muscles; Muscular Diseases; Muscular Dystrophies; Myofibrils; Prostaglandin Antagonists; Prostaglandins E | 1985 |
16,16-Dimethyl prostaglandin E2 suppresses the increases in the proliferative activity of rat colonic epithelium induced by indomethacin and aspirin.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Autoradiography; Cell Division; Cell Membrane; Colon; DNA; Drug Antagonism; Epithelium; Female; Indomethacin; Intestinal Mucosa; Microscopy, Electron; Ornithine Decarboxylase; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Thymidine | 1985 |
Antihemostatic and antithrombotic effects of XC386.
Topics: Animals; Aspirin; Blood Coagulation; Hematocrit; Heparin; Indomethacin; Mice; Platelet Aggregation; Pyrazoles; Shock, Septic; Thrombosis; Time Factors | 1985 |
Heparin-induced platelet aggregation is inhibited by antagonists of the thromboxane pathway.
Topics: Aspirin; Bleeding Time; Heparin; Heparin Antagonists; Humans; Indomethacin; Platelet Aggregation; Prostanoic Acids; Thromboxanes | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin | 1985 |
The effect of antiinflammatory drugs on plasma fibronectin.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Fibronectins; Indomethacin; Male; Phenylbutazone; Rats; Rats, Inbred Strains | 1985 |
[In vitro effects of non-steroidal anti-inflammatory drugs on production of oxygen radicals evaluated by the chemiluminescent response of polymorphonuclear leukocytes].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cell Membrane; Diclofenac; Free Radicals; Humans; Indomethacin; Luminescent Measurements; Neutrophils; Oxygen; Piroxicam; Thiazines; Zymosan | 1985 |
Possible indomethacin-aminoglycoside interaction in preterm infants.
Topics: Aminoglycosides; Animals; Aspirin; Drug Interactions; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Rats | 1985 |
Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers.
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Chronic Disease; Cysteamine; Dogs; Duodenal Ulcer; Female; Gastric Acid; Guinea Pigs; Histamine; Hot Temperature; Indomethacin; Male; Physical Exertion; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1985 |
Cytoprotective and antisecretory properties of a non-diarrheogenic and non-uterotonic prostacyclin analog: U-68,215.
Topics: Alprostadil; Animals; Anti-Ulcer Agents; Aspirin; Bleeding Time; Blood Pressure; Digestive System; Dogs; Embryo Implantation; Epoprostenol; Female; Gastric Juice; Indomethacin; Intestines; Platelet Aggregation; Rats; Rats, Inbred Strains; Stomach; Uterine Contraction | 1985 |
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Osteoarthritis; Sulindac; Tolmetin | 1985 |
Relative toxicities of several nonsteroidal antiinflammatory compounds in primary cultures of rat hepatocytes.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; L-Lactate Dehydrogenase; Liver; Propionates; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Effects of intracerebroventricular bombesin on gastric ulcers and gastric glycoproteins in rats.
Topics: Animals; Aspirin; Bombesin; Chromatography, Gel; Gastric Acid; Gastric Mucosa; Glycoproteins; Indomethacin; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1985 |
Aspirin-like drugs and prostaglandins.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Fever; Humans; Indomethacin; Injections, Spinal; Prostaglandin Antagonists; Prostaglandins; Sodium Salicylate | 1971 |
Inhibition of prostaglandin release and the control of threatened abortion.
Topics: Abortion, Threatened; Aspirin; Blood Platelets; Female; Humans; Indomethacin; Lung; Obstetric Labor Complications; Pregnancy; Prostaglandin Antagonists; Prostaglandins; Spleen | 1971 |
Gastrointestinal bleeding: a possible association with ibuprofen.
Topics: Acetaminophen; Aminopyrine; Analgesics; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Child; Dextropropoxyphene; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Mefenamic Acid; ortho-Aminobenzoates; Phenylacetates; Phenylbutazone; Platelet Adhesiveness; Propionates; Toluene | 1972 |
Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys.
Topics: Acetamides; Animals; Anticholesteremic Agents; Antipyrine; Aspirin; Blood Proteins; Carbon Isotopes; Chlorothiazide; Clofibrate; Dicumarol; Digitoxin; Drug Interactions; Fluorine; Glycolates; Half-Life; Haplorhini; Humans; Hypolipidemic Agents; Indomethacin; Macaca; Phenothiazines; Phenylbutazone; Salicylates; Warfarin | 1972 |
Pain in haemophilia.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemophilia A; Humans; Indomethacin; Male; Pain; Phenylbutazone; Suppositories | 1973 |
Anti-metastatic effect of aspirin.
Topics: Animals; Aspirin; Bone Neoplasms; Bone Resorption; Carcinoma 256, Walker; Indomethacin; Lysosomes; Neoplasm Metastasis; Rats | 1973 |
Anti-metastatic effect of aspirin.
Topics: Animals; Aspirin; Bone Neoplasms; Bone Resorption; In Vitro Techniques; Indomethacin; Mice; Neoplasm Metastasis; Prostaglandins | 1973 |
Indomethacin in breast cancer.
Topics: Aged; Animals; Aspirin; Breast Neoplasms; Female; Humans; Indomethacin; Mice; Rats | 1973 |
Inhibition of protein aggregation by vitamin E and selenium.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Cattle; Freund's Adjuvant; gamma-Globulins; Hot Temperature; Humans; Hydrocortisone; In Vitro Techniques; Indomethacin; Phenylbutazone; Rats; Selenium; Serum Albumin, Bovine; Vitamin E | 1974 |
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depression, Chemical; Dicumarol; Erythrocytes; Fibrinolysis; Flufenamic Acid; Hemolysis; Humans; Hypotonic Solutions; In Vitro Techniques; Indomethacin; Inflammation; Mefenamic Acid; Oxyphenbutazone; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Pyrazoles; Receptors, Drug; Structure-Activity Relationship | 1972 |
Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs.
Topics: Angiotensin II; Animals; Aorta; Arachidonic Acids; Arachis; Aspirin; Bradykinin; Guinea Pigs; Half-Life; Histamine Release; In Vitro Techniques; Indomethacin; Injections, Intra-Arterial; Linolenic Acids; Lung; Male; Muscle Contraction; Oils; Ovalbumin; Particle Size; Prostaglandins; Rabbits; Rats; Vasoconstrictor Agents | 1973 |
Prostaglandins and in vitro TSH-dependent iodide binding by rat thyroid glands.
Topics: Animals; Aspirin; Glucose; Indomethacin; Iodides; Male; Oxidation-Reduction; Prostaglandins; Protein Binding; Rats; Stimulation, Chemical; Thyroid Function Tests; Thyroid Gland; Thyrotropin | 1974 |
A study of prostaglandins and prostaglandin antagonists in relation to anaphylaxis in calves.
Topics: Anaphylaxis; Animals; Aspirin; Blood Pressure; Bradykinin; Cattle; Dibenzoxazepines; Diethylcarbamazine; Dose-Response Relationship, Drug; gamma-Globulins; Histamine; Horses; Hydrazines; Indomethacin; Male; Perfusion; Phenylbutazone; Polyphloretin Phosphate; Prostaglandin Antagonists; Prostaglandins; Serotonin | 1974 |
Formation of a factor increasing vascular permeability during electrical stimulation of the saphenous nerve in rats.
Topics: Acetylcholine; Animals; Aspirin; Bradykinin; Capillary Permeability; Carboxypeptidases; Chymotrypsin; Dialysis; Electric Stimulation; Histamine; Indomethacin; Kininogens; Kinins; Leg; Male; Neurons; Perfusion; Prostaglandins; Proteins; Rats; Serotonin; Staining and Labeling; Substance P; Trypsin | 1974 |
Gastric mucosal damage induced by non-steroid anti-inflammatory agents in rats of different ages.
Topics: Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Body Weight; Dose-Response Relationship, Drug; Edema; Flufenamic Acid; Gastric Mucosa; Indomethacin; Phenylbutazone; Quinolines; Rats | 1972 |
Inhibition of vasopressin-stimulated water transport across the isolated toad bladder.
Topics: Animals; Aspirin; Biochemistry; Biological Transport; Bufo marinus; Chromatography, Thin Layer; In Vitro Techniques; Indomethacin; Kinetics; Sodium; Sodium Chloride; Stimulation, Chemical; Theophylline; Tissue Extracts; Urinary Bladder; Vasopressins; Water | 1973 |
Pharmacological analysis of the acute inflammatory process induced in the rat's paw by local injection of carrageenin and by heating.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Burns; Carrageenan; Edema; Histamine H1 Antagonists; Indomethacin; Inflammation; Male; Perfusion; Permeability; Rats; Serotonin Antagonists; Time Factors | 1973 |
Total and free-plasma tryptophan concentrations in rheumatoid disease.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Estrogens; Female; Humans; Indomethacin; Male; Middle Aged; Piperazines; Prednisolone; Protein Binding; Tryptophan; Ultrafiltration | 1973 |
Inhibition by non-steroidal anti-inflammatory agents of the release of rabbit aorta contracting substance and prostaglandins from chopped guinea-pig lungs.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aspirin; Female; Flufenamic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Phenylbutazone; Physical Stimulation; Prostaglandin Antagonists; Prostaglandins; Rabbits; Sodium Salicylate; Stomach | 1974 |
Influence of adrenergic drugs on prostaglandin E release from the dog kidney,.
Topics: Adrenergic alpha-Agonists; Animals; Aspirin; Dogs; Epinephrine; Female; Indomethacin; Isoproterenol; Kidney; Male; Norepinephrine; Perfusion; Phenoxybenzamine; Prostaglandins; Radioimmunoassay; Regional Blood Flow | 1974 |
Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. II) Protective activity against drug-induced experimental ulcers.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hydrocortisone; Imidazoles; Indomethacin; Parasympatholytics; Phenylbutazone; Pyridines; Rats; Stomach Ulcer | 1974 |
Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. IV) Enhancement of gastric mucus production in different experimental models.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cold Temperature; Gastric Mucins; Gastric Mucosa; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Immobilization; Indomethacin; Parasympatholytics; Peptic Ulcer; Phenylbutazone; Pyridines; Rats; Stomach; Stomach Ulcer; Stress, Physiological | 1974 |
Effect of anti-inflammatory agents on platelets.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Codeine; Dextropropoxyphene; Gentisates; Humans; Indomethacin; ortho-Aminobenzoates; Oxyphenbutazone; Phenacetin; Phenylacetates; Phenylbutazone; Sodium Salicylate | 1968 |
Symptomatic control of fever in lymphoma and leukemia.
Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Aspirin; Female; Fever; Hodgkin Disease; Humans; Indomethacin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Palliative Care; Prednisone | 1969 |
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Edema; Enzyme Activation; Female; Flufenamic Acid; Granuloma; Guinea Pigs; Histamine Release; Hot Temperature; Hydrocortisone; Immune Sera; Indomethacin; Injections, Intramuscular; Kaolin; Male; Peptide Hydrolases; Phenylbutazone; Rats; Serotonin; Serratia; Time Factors | 1969 |
Prostaglandin synthesis, inhibition, and intraocular pressure.
Topics: Animals; Aqueous Humor; Arachidonic Acids; Ascorbic Acid; Aspirin; Dose-Response Relationship, Drug; Indomethacin; Intraocular Pressure; Prostaglandin Antagonists; Prostaglandins; Proteins; Rabbits; Time Factors; Tonometry, Ocular | 1973 |
Biosynthesis of prostaglandin E 2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs.
Topics: Arachidonic Acids; Aspirin; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Dexamethasone; Edetic Acid; Fatty Acids, Unsaturated; Humans; Indomethacin; Kinetics; Microsomes; Prostaglandins; Skin; Subcellular Fractions; Time Factors; Triamcinolone Acetonide | 1973 |
The effect of disodium cromoglycate and PGF2 alpha on acute cutaneous reactions of the guinea pig and rat.
Topics: Animals; Aspirin; Cromolyn Sodium; Guinea Pigs; Indomethacin; Injections, Intradermal; ortho-Aminobenzoates; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Phospholipases; Prostaglandins; Rats; Toluene | 1973 |
Prostaglandin regulation of airway smooth muscle tone.
Topics: Acetylcholine; Animals; Aspirin; Biological Assay; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandin Antagonists; Prostaglandins; Rats; Stomach; Trachea | 1973 |
Enhancement of metabolic coronary dilatation by aspirin-like substances by suppression of prostaglandin feedback control?
Topics: Animals; Aspirin; Calcium; Coronary Vessels; Feedback; Heart Rate; Indomethacin; Infusions, Parenteral; Male; Norepinephrine; Prostaglandin Antagonists; Prostaglandins; Rats; Regional Blood Flow; Vasodilator Agents | 1973 |
Correlations between pathological changes in the hind paws of rats with adjuvant arthritis and their response to anti-inflammatory and analgesic drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Body Temperature; Body Weight; Dextropropoxyphene; Disease Models, Animal; Foot; Indomethacin; Male; Mycobacterium tuberculosis; Rats; Time Factors | 1973 |
Prostaglandins, calcium metabolism and cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Cells, Cultured; Fatty Acids, Unsaturated; Fibrosarcoma; Hydroxycholecalciferols; Hypercalcemia; Immunoassay; Indomethacin; Mice; Parathyroid Hormone; Prostaglandin Antagonists; Prostaglandins; Sarcoma, Experimental; Tritium | 1974 |
The prophylactic and therapeutic effects of gold sodium thiomalate against adjuvant-induced polyarthritis in rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Aspirin; Blood Sedimentation; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Gold Sodium Thiomalate; Hydrocortisone; Indomethacin; Male; Mycobacterium tuberculosis; Rats; Time Factors | 1973 |
Editorial: Prostaglandins--tour d'horizon.
Topics: Abortion, Induced; Aspirin; Female; Humans; Indomethacin; Kidney; Natriuresis; Phenylbutazone; Pregnancy; Prostaglandin Antagonists; Prostaglandins; Uterus | 1974 |
Drugs which inhibit prostaglandin biosynthesis.
Topics: Acetaminophen; Antioxidants; Arachidonic Acids; Aspirin; Blood Platelets; Dronabinol; Fatty Acids; Hypertension; Indomethacin; Kinetics; Metals; Microsomes; Mixed Function Oxygenases; Oxidoreductases; Prostaglandin Antagonists; Prostaglandins; Salicylates; Species Specificity; Structure-Activity Relationship; Subcellular Fractions; Terminology as Topic; Time Factors | 1974 |
Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro.
Topics: Acetylcholine; Animals; Aspirin; Bradykinin; Cattle; Depression, Chemical; Diethylcarbamazine; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; ortho-Aminobenzoates; Phenylbutazone; Phloretin; Prostaglandin Antagonists; Prostaglandins; Pulmonary Veins; Serotonin; Stimulation, Chemical; Toluene | 1974 |
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Borohydrides; Carbon Radioisotopes; Chromatography, Thin Layer; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Mass Spectrometry; Oxygenases; Peroxides; Platelet Aggregation; Prostaglandins | 1974 |
Prostaglandin synthetase system--resolution into oxygenase and isomerase components.
Topics: Animals; Aspirin; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Ethylene Glycols; Fatty Acids, Unsaturated; Glutathione; Haplorhini; Hemoglobins; Indomethacin; Isomerases; Male; Microsomes; Multienzyme Complexes; Oxidation-Reduction; Oxygenases; Peroxides; Polysorbates; Prostaglandins; Seminal Vesicles; Tin; Tryptophan | 1974 |
[Studies on anti-inflammatory agents. XVII. Effects of 2-amino-3-ethoyxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (Y-3642) hydrochoride on oxidative phosphorylation, swelling and adenosine triphosphatase of rat liver mitochondria].
Topics: Adenosine Triphosphatases; Animals; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; In Vitro Techniques; Indomethacin; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Phenylacetates; Phenylbutazone; Pyridines; Rats; Stimulation, Chemical; Thiophenes | 1971 |
Effect of anti-inflammatory compounds on actomyosin-adenosinetriphosphate interaction.
Topics: Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Aspirin; Benzene Derivatives; Calcium; Chemical Phenomena; Chemical Precipitation; Chemistry; Chlorine; Chloromercuribenzoates; Densitometry; Enzyme Activation; Flufenamic Acid; Hydrolysis; Indomethacin; Light; Magnesium; Mefenamic Acid; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Organomercury Compounds; Phenols; Phenylacetates; Phenylbutazone; Propionates; Rabbits; Salicylates; Scattering, Radiation | 1970 |
[Influence of various drugs on the tissue permeability. 6. Effect of anti-inflammatory drugs on quantitative changes in connective tissue components in inflamed tissues of filter paper-implanted rats].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Barbiturates; Benzyl Compounds; Connective Tissue; Cyclohexanes; Dexamethasone; Dimethylamines; Female; Flufenamic Acid; Glycosaminoglycans; Hexosamines; Hydroxyproline; Indazoles; Indomethacin; Inflammation; Neuraminic Acids; Phenylbutazone; Prednisolone; Rats; Time Factors; Uronic Acids | 1973 |
Method of treatment of rheumatoid arthritis in different countries.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chloroquine; Dimethyl Sulfoxide; England; Europe; Flufenamic Acid; Gold; Humans; Indomethacin; Injections, Intra-Articular; Japan; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Prednisolone; Salicylates; South America; United States | 1966 |
Hazards of drugs for rheumatoid arthritis.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Analgesics; Arthritis, Rheumatoid; Aspirin; Indomethacin; Oxyphenbutazone; Phenylbutazone; Steroids | 1967 |
Effect of gold salts and other drugs on the release and activity of lysosomal hydrolases.
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Cathepsins; Depression, Chemical; Glucuronidase; Gold; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Hydrolases; In Vitro Techniques; Indomethacin; Knee Joint; Liver; Lysosomes; Osteoarthritis; Phenylbutazone; Phosphoric Monoester Hydrolases; Rabbits; Sulfhydryl Compounds; Synovial Fluid | 1968 |
Isolation of the anti-inflammatory principles from Achillea millefolium (Compositae).
Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Aspirin; Chromatography; Colorimetry; Dexamethasone; Edema; Electrophoresis, Disc; Female; Hydrocortisone; Indomethacin; Methods; Mice; Phenylbutazone; Plants, Medicinal | 1969 |
Ingibition of elastase and collagenase by anti-inflammatory drugs.
Topics: Aminocaproates; Anti-Inflammatory Agents; Aspirin; Butyrates; Cortisone; Dexamethasone; Flufenamic Acid; Indomethacin; Microbial Collagenase; Pancreatic Elastase; Phenylbutazone | 1970 |
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Dextrans; Dimethyl Sulfoxide; Disease Models, Animal; Edema; Flufenamic Acid; Formaldehyde; Granuloma; Indomethacin; Inflammation; Kaolin; Male; Mefenamic Acid; Ovalbumin; Oxyphenbutazone; Phenylbutazone; Prednisolone; Rats; Sodium Salicylate; Trypsin | 1971 |
Endogenous prostaglandins modulate lipolytic processes in adipose tissue.
Topics: Acetates; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Aspirin; Cyclic AMP; Cyclopentanes; Dibenzoxazepines; Dicarboxylic Acids; Epinephrine; Fatty Acids; Hydrazines; In Vitro Techniques; Indomethacin; Lipid Metabolism; Prostaglandin Antagonists; Prostaglandins; Rats; Theophylline | 1971 |
Nongouty crystal deposit arthritis.
Topics: Adrenocorticotropic Hormone; Aspirin; Bursitis; Chondrocalcinosis; Colchicine; Heart Failure; Humans; Hyperparathyroidism; Indomethacin; Phenylbutazone; Synovial Fluid; Tendinopathy; Uric Acid | 1971 |
Use of adsorbents in enhancement of drug dissolution. I.
Topics: Absorption; Aspirin; Chemistry, Pharmaceutical; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Lactose; Pharmaceutical Preparations; Silicon Dioxide; Solubility; Starch | 1972 |
Use of adsorbents in enhancement of drug dissolution. II.
Topics: Adsorption; Aspirin; Chromatography, Thin Layer; Crystallography; Diffusion; Indomethacin; Infrared Rays; Pharmaceutical Preparations; Radiation; Reserpine; Silicon Dioxide; Solubility; Spectrum Analysis; Temperature; Thermography; Ultraviolet Rays | 1972 |
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
Topics: Acetates; Animals; Aspirin; Carcinoma, Hepatocellular; Complement System Proteins; Dogs; Histamine; Humans; Hydrogen-Ion Concentration; Immune Sera; In Vitro Techniques; Indomethacin; Lipids; Liver; Liver Neoplasms; Mice; Muscle Contraction; Muscles; Neoplasms, Experimental; Prostaglandin Antagonists; Prostaglandins; Rats; Stomach; Time Factors | 1973 |
Control by TSH of a phospholipase A 2 activity, a limiting factor in the biosynthesis of prostaglandins in the thyroid.
Topics: Acetates; Adenylyl Cyclases; Animals; Arachidonic Acids; Aspirin; Carbon Isotopes; Chromatography, Thin Layer; Cyclic AMP; In Vitro Techniques; Indomethacin; Phosphatidylinositols; Phospholipases; Phospholipids; Prostaglandins; Stimulation, Chemical; Swine; Thyroid Gland; Thyrotropin | 1973 |
Cholera enterotoxin: failure of anti-inflammatory agents to prevent cyclic AMP accumulation.
Topics: Aspirin; Cyclic AMP; Enterotoxins; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Vibrio | 1973 |
Inhibition of functional vasodilatation and prostaglandin formation in rabbit adipose tissue by indomethacin and aspirin.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Aspirin; Blood Flow Velocity; Blood Pressure; Depression, Chemical; Fatty Acids, Nonesterified; Ileum; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rabbits; Time Factors; Vasodilator Agents | 1973 |
[Qualitative changes in prostaglandins in kidneys of normotonic and hypertonic animals under the effect of aspirin-like preparations].
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Hypertension; Indomethacin; Prostaglandins; Rats; Secretory Rate | 1972 |
Effect of anti-inflammatory drugs on the binding of calcium to cellular membranes in various human and guinea-pig tissues.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Aspirin; Binding Sites; Calcium; Electron Transport Complex IV; Endothelium; Flufenamic Acid; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Membranes; Mitochondria, Muscle; Muscle, Smooth; Phenylacetates; Phenylbutazone; Umbilical Cord | 1973 |
Prostaglandins and the thyroid gland.
Topics: Adenylyl Cyclases; Animals; Aspirin; Carbon Radioisotopes; Cattle; Cyclic AMP; Dogs; Glucose; In Vitro Techniques; Indomethacin; Phospholipids; Phosphorus; Phosphorus Radioisotopes; Prostaglandin Antagonists; Prostaglandins; Stimulation, Chemical; Thyroid Gland; Thyrotropin | 1974 |
Effects of prostaglandin E1, ethanol and TSH on the adenylate cyclase activity of beef thyroid plasma membranes and cyclic AMP content of dog thyroid slices.
Topics: Adenylyl Cyclases; Animals; Aspirin; Cattle; Cell Membrane; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Ethanol; Glucose; Indomethacin; Prostaglandins; Rats; Thyroid Gland; Thyrotropin | 1974 |
Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices.
Topics: Acetylcholine; Angiotensin II; Animals; Aspirin; Bradykinin; Culture Techniques; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Indomethacin; Isoproterenol; Lung; Peptides; Promethazine; Stimulation, Chemical; Theophylline | 1973 |
Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin.
Topics: Adenylyl Cyclases; Animals; Aspirin; Cholera; Cyclic AMP; Drug Synergism; Enterotoxins; Enzyme Activation; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Intestinal Secretions; Prostaglandins; Rabbits; Theophylline; Time Factors; Vibrio cholerae | 1974 |
Effect of nonsteroidal antiinflammatory drugs on plasma protein-thyroxine interaction.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Barbiturates; Binding Sites; Blood Proteins; Cyclohexanes; Feces; Flufenamic Acid; Indomethacin; Iodine; Iodine Radioisotopes; Male; Mefenamic Acid; Mesylates; Muscles; Oxyphenbutazone; Phenylacetates; Phenylbutazone; Protein Binding; Rats; Resins, Plant; Sodium Salicylate; Thyroid Gland; Thyroidectomy; Thyroxine | 1974 |
Effects of prostaglandins, cyclic AMP, seminal plasma, indomethacin, and other factors on oviposition in the Japanese quail, Coturnix coturnix japonica.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Cattle; Coturnix; Drug Synergism; Female; Horses; Humans; Indomethacin; Linoleic Acids; Male; Oviposition; Poultry; Propylene Glycols; Prostaglandins; Quail; Radioimmunoassay; Semen; Swine; Theophylline; Turkeys | 1974 |
Inhibition of human leucocyte collagenase by some drugs used in the therapy of rheumatic diseases.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Collagen; Cyclophosphamide; Electrophoresis, Polyacrylamide Gel; Flufenamic Acid; Gold; Humans; Hydrocortisone; Hydrolysis; Hydroxyproline; In Vitro Techniques; Indomethacin; Leukocytes; Microbial Collagenase; Phenylbutazone; Protein Denaturation; Thiosulfates; Trypsin | 1974 |
The effects of some anti-inflammatory drugs on the acute-phase proteins in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Adult; Analgesics; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; C-Reactive Protein; Fibrinogen; Glucocorticoids; Haptoglobins; Humans; Indomethacin; Prednisone | 1973 |
Relaxation of retracted clots: a thrombelastographic study.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Clot Retraction; Cyclic AMP; Humans; Indomethacin; Papaverine; Prostaglandins; Pyrimidines; Theophylline; Thrombelastography | 1974 |
Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid (Wy-23,049)--comparison with acetylsalicylic acid.
Topics: Acrylates; Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Chlorobenzenes; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Lysine; Platelet Adhesiveness; Platelet Aggregation; Polymers; Prostaglandins; Rats; Rats, Inbred Strains; Thiazoles; Time Factors | 1974 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Flufenamic Acid; Gold; Humans; Immunosuppressive Agents; Indomethacin; Lupus Erythematosus, Systemic; Mefenamic Acid; Osteoarthritis; Oxyphenbutazone; Phenylbutazone; Polymyalgia Rheumatica; Prednisolone; Prednisone; Psoriasis; Rheumatic Diseases; Spondylitis, Ankylosing; Stomach Ulcer | 1974 |
Evaluation of the potential of gastric ulceration after administration of certain drugs.
Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Aspirin; Chlorpromazine; Cortisone; Desoxycorticosterone; Diphenhydramine; Female; Indomethacin; Male; Phenylbutazone; Prednisone; Procaine; Quaternary Ammonium Compounds; Rats; Reserpine; Stomach Ulcer; Tetracaine | 1967 |
Bradykinin induced bronchoconstriction in guinea pigs and its modification by various agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Bradykinin; Bronchi; Chlorpromazine; Drug Antagonism; Drug Synergism; Ethanolamines; Female; Guinea Pigs; Histamine; Indomethacin; Male; Methysergide; Oxyphenbutazone; Phenacetin; Phenoxybenzamine; Phenylbutazone; Sulfinpyrazone; Tripelennamine | 1967 |
Alleviation of the leg abnormality in zinc-deficient chicks by histamine and by various anti-arthritic agents.
Topics: Amine Oxidase (Copper-Containing); Animals; Arthritis; Aspirin; Chickens; Congenital Abnormalities; Cortisone; Deficiency Diseases; Diet; Gold; Guanidines; Histamine; Histamine H1 Antagonists; Indomethacin; Leg; Phenylbutazone; Zinc | 1968 |
Interaction of aspirin with nonsteroidal anti-inflammatory drugs in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Drug Antagonism; Edema; Indomethacin; Male; Phenylbutazone; Rats | 1968 |
The effect of acetylsalicylic acid, phenylbutazone and indomethacin on the binding of 11-hydroxysteroids to plasma proteins in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Blood Proteins; Fluorometry; Humans; Hydrocortisone; Indomethacin; Phenylbutazone; Protein Binding; Spectrophotometry | 1968 |
The effect of anti-inflammatory drugs on the protein-binding of 11-hydroxysteroids in human plasma in vitro.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Female; Humans; Indomethacin; Oxyphenbutazone; Peptides; Phenylacetates; Phenylbutazone; Pregnancy; Protein Binding; Serum Albumin | 1969 |
Effects of some anti-inflammatory drugs on capillary permeability of the gastric mucosa in the rat.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Coloring Agents; Cortisone; Gastric Juice; Gastric Mucosa; Hydrogen-Ion Concentration; Indicators and Reagents; Indomethacin; Male; Phenylbutazone; Plant Extracts; Plasma Volume; Quinolines; Rats; Stomach | 1969 |
Modification of the Randall-Selitto analgesic apparatus.
Topics: Analgesics; Animals; Aspirin; Atmospheric Pressure; Dextropropoxyphene; Indomethacin; Methods; Morphine; Pharmacology; Phenylbutazone; Rats | 1969 |
The inhibitory effect of non-steroidal anti-inflammatory agents on aggregation of red cells in vitro.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Sedimentation; Dextrans; Erythrocytes; Female; Fibrinogen; Flufenamic Acid; Gelatin; Glucocorticoids; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Male; Mefenamic Acid; Phenylbutazone; Rats; Salicylates | 1970 |
The effects of anti-inflammatory drugs on the protein-binding of [1,2-3H] cortisol in human plasma in vitro.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Humans; Hydrocortisone; Indomethacin; Oxyphenbutazone; Phenylacetates; Protein Binding; Tritium | 1971 |
Effects of some drugs on capillary permeability in the anaphylaxis of the mouse.
Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Aprotinin; Aspirin; Body Temperature; Capillary Permeability; Chloroquine; Chlorpromazine; Cortisone; Cyclizine; Depression, Chemical; Desensitization, Immunologic; Diphenhydramine; Epinephrine; Female; Glycyrrhiza; Histamine H1 Antagonists; Indomethacin; Mice; Oxyphenbutazone; Phenylbutazone; Plants, Medicinal; Promethazine; Rectum; Reserpine; Splenectomy; Triprolidine | 1971 |
Prostaglandins and anti-inflammatory drugs in the dog knee joint.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Indomethacin; Inflammation; Knee Joint; Phenylbutazone; Prostaglandin Antagonists; Synovitis | 1972 |
Non-steroidal anti-inflammatory drugs and leucocyte emigration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dextrans; Flufenamic Acid; Indomethacin; Leukocytes; Male; Phenylbutazone; Pleurisy; Rats | 1972 |
A modification of rat adjuvant arthritis for testing antirheumatic drugs.
Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Dexamethasone; Disease Models, Animal; Female; Flufenamic Acid; Gold; Hydrocortisone; Indomethacin; Inflammation; Phenylbutazone; Prednisolone; Rats; Thiomalates | 1972 |
Proceedings: Lipid A and prostaglandin.
Topics: Acetaminophen; Animals; Aspirin; Cats; Endotoxins; Fever; Indomethacin; Lipids; Prostaglandins | 1974 |
Quantitation of thermography in arthritis using multi-isothermal analysis. II. Effect of nonsteroidal anti-inflammatory therapy on the thermographic index.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Arthritis, Rheumatoid; Aspirin; Foot; Gout; Hand; Humans; Indomethacin; Injections, Intra-Articular; Knee; Prednisolone; Salicylates; Thermography | 1974 |
Release from washed platelets induced by strontium ions and calcium ions: indications for two different mechanisms of action.
Topics: Adenine Nucleotides; Aspirin; Blood Platelets; Calcium; Cyproheptadine; Glycolysis; Humans; Indomethacin; Mitochondria; Models, Biological; Oxygen Consumption; Serotonin; Strontium; Thrombin; Tritium | 1974 |
Light emission during the action of prostaglandin synthetase.
Topics: Animals; Arachidonic Acids; Aspirin; Carotenoids; Catalase; Cattle; Half-Life; Indomethacin; Kinetics; Luminescent Measurements; Male; Microsomes; Mixed Function Oxygenases; Multienzyme Complexes; Oxygen Consumption; Photochemistry; Prostaglandins; Seminal Vesicles; Sheep; Subcellular Fractions; Sulfhydryl Compounds; Superoxide Dismutase; Time Factors | 1974 |
Adenosine triphosphate-induced contractile process in rat lymphocytes and its inhibition by anti-inflammatory agents.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Indomethacin; Lymphocytes; Phenylbutazone; Rats | 1974 |
Determination of the therapeutic mean effective doses of several anti-inflammatory agents in adjuvant arthritic rats.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dose-Response Relationship, Drug; Freund's Adjuvant; Hydrocortisone; Indomethacin; Male; Mefenamic Acid; Phenylbutazone; Prednisolone; Rats; Time Factors | 1974 |
Pain in osteoarthrosis.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Cartilage Diseases; Exercise Therapy; Hip; Humans; Immobilization; Indomethacin; Inflammation; Joints; Knee; Movement; Osteoarthritis; Oxyphenbutazone; Pain; Phenylbutazone; Rheumatoid Factor; Sexual Behavior; Stress, Psychological | 1974 |
A comparison of the inhibitory activity of compounds on ocular prostaglandin biosynthesis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Cell Fractionation; Ciliary Body; Conjunctiva; Dexamethasone; Eye; Female; In Vitro Techniques; Indoles; Indomethacin; Iris; Male; Microsomes; Mixed Function Oxygenases; Multienzyme Complexes; Oxyphenbutazone; Phenylbutazone; Phenylpropionates; Propionates; Prostaglandins; Pyrroles; Rabbits; Tissue Extracts | 1974 |
Carrageenin hyperthermia in rats.
Topics: Animals; Aspirin; Body Temperature; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fever; Hindlimb; Indomethacin; Models, Biological; Phenylbutazone; Prostaglandins; Rats | 1974 |
Prostaglandins in synovial inflammatory disease.
Topics: Arthritis; Aspirin; Hemophilia A; Humans; Indomethacin; Inflammation; Prostaglandins; Synovial Fluid | 1974 |
[Acid phosphatase of the blood serum in rheumatism].
Topics: Acid Phosphatase; Adult; Aspirin; Female; Humans; Indomethacin; Male; Prednisolone; Rheumatic Heart Disease | 1974 |
[Current aspects of treatment and prevention of rheumatic fever in children].
Topics: Aminopyrine; Aspirin; Benzoates; Child; Chloroquine; Humans; Immunosuppressive Agents; Indomethacin; Phenylpropionates; Rheumatic Fever; Steroids | 1974 |
[Incidence of thrombosis and the status of coagulation in ischaemic heart disease].
Topics: Acute Disease; Aspirin; Blood Coagulation; Chronic Disease; Coronary Disease; Depression, Chemical; Humans; Indomethacin; Myocardial Infarction; Phenylbutazone; Platelet Adhesiveness; Platelet Aggregation; Sulfinpyrazone | 1974 |
Blood platelets and the inflammatory process.
Topics: Aspirin; Blood Platelets; Blood Proteins; Capillary Permeability; Hemostasis; Histamine; Humans; Indomethacin; Inflammation; Molecular Weight; Platelet Aggregation; Prostaglandins; Serotonin; Thrombin; Thrombosis | 1974 |
Adverse reactions to non-steroidal antirheumatic drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liver Injury; Gastrointestinal Diseases; Gold; Hematologic Diseases; Humans; Indomethacin; Liver; Naphthaleneacetic Acids; Oxyphenbutazone; Penicillamine; Phenacetin; Phenyl Ethers; Phenylacetates; Phenylbutazone; Propionates; Registries; United Kingdom | 1974 |
Prostaglandin production by human epidermal cells in vitro: a model for studying pharmacologic inhibition of prostaglandin synthesis.
Topics: Aspirin; Cells, Cultured; Cross Reactions; Humans; Indomethacin; Prostaglandins; Radioimmunoassay; Skin | 1974 |
Inhibition by indomethacin and aspirin of 15-hydroxyprostaglandin dehydrogenase in vitro.
Topics: Alcohol Oxidoreductases; Animals; Aspirin; Cattle; Chromatography, Gel; Chromatography, Thin Layer; In Vitro Techniques; Indomethacin; Isoelectric Focusing; Lung; Prostaglandins | 1974 |
Alterations in platelet aggregation associated with adjuvant arthritis in rats.
Topics: Adenosine Diphosphate; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Collagen; Disease Models, Animal; Female; Fibrinogen; Indomethacin; Mycobacterium; Phenylbutazone; Platelet Adhesiveness; Platelet Aggregation; Rats; Time Factors | 1974 |
The effect of antiinflammatory drugs on the blood coagulation system.
Topics: Anti-Inflammatory Agents; Apazone; Aspirin; Blood Coagulation; Blood Platelets; Chloroquine; Cortisone; Gold; Humans; Indomethacin; Niflumic Acid; Penicillamine; Pyrazoles | 1974 |
][A new method for screening of analgesics applied to heat induced inflammatory pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats | 1974 |
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Evaluation, Preclinical; Edema; Female; Fever; Granuloma; Indomethacin; Male; Mice; Pain; Phenylbutazone; Phthalazines; Pyridazines; Rabbits; Rats | 1974 |
Effects of anti-inflammatory drugs on prostaglandin biosynthesis.
Topics: Acetaminophen; Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Azathioprine; Benzoates; Biological Assay; Clofibrate; Dexamethasone; Dogs; Edema; Fludrocortisone; Hydrocortisone; In Vitro Techniques; Indomethacin; Mefenamic Acid; Oxygenases; Phenylbutazone; Prostaglandins; Rats; Spleen; Triamcinolone Acetonide | 1972 |
Enzyme release from guinea-pig polymorphonuclear leucocyte lysosomes inhibited in vitro by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Cyclophosphamide; Depression, Chemical; Flufenamic Acid; Galactosidases; Glucuronidase; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Indomethacin; Leukocytes; Lysosomes; Methotrexate; Phenylbutazone; Sulfatases | 1972 |
Platelet aggregation induced by arachidonic acid is accompanied by release of potential inflammatory mediators distinct from PGE2 and PGF2.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Biological Assay; Blood Platelets; Clofibrate; Glycerol; Indomethacin; Inflammation; Phenylbutazone; Platelet Adhesiveness; Prostaglandins; Tissue Extracts; Vasoconstrictor Agents | 1973 |
Prostaglandins reverse inhibition of electrically-induced contractions of guinea pig ileum by morphine, indomethacin and acetylsalicylic acid.
Topics: Animals; Aspirin; Binding, Competitive; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Morphine; Muscle Contraction; Muscles; Prostaglandins; Receptors, Drug | 1973 |
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Fatty Acids, Unsaturated; Fatty Alcohols; Humans; Indomethacin; Peroxides; Platelet Aggregation; Prostaglandins; Thrombin | 1974 |
Drug treatment of connective tissue disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Azathioprine; Chloroquine; Collagen Diseases; Cyclophosphamide; Gold; Humans; Immunosuppressive Agents; Indomethacin; Penicillamine; Phenacetin; Phenylbutazone | 1974 |
[Analgesics in dentistry].
Topics: Acetanilides; Agranulocytosis; Analgesics; Anesthesia, Dental; Aspirin; Blood Coagulation; Caffeine; Codeine; Drug Combinations; Flufenamic Acid; Gastrointestinal Hemorrhage; Heterocyclic Compounds; Humans; Indomethacin; Mefenamic Acid; Morphinans; Mouth Diseases; ortho-Aminobenzoates; Phenacetin | 1972 |
Analgesics and non-steroid anti-inflammatory agents in rheumatic disease.
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bone Neoplasms; Gout; Humans; Indomethacin; Osteoarthritis; Oxyphenbutazone; Phenylbutazone; Rheumatic Diseases; Spondylitis, Ankylosing | 1972 |
Which drugs for which rheumatic disorder?
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Gold; Gout; Humans; Indomethacin; Lupus Erythematosus, Systemic; Osteoarthritis; Phenylbutazone; Prednisolone; Pyrazoles; Rheumatic Diseases; Spondylitis, Ankylosing | 1972 |
Gastric mucosal damage by anti-inflammatory drugs.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diffusion; Gastric Mucins; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Humans; Hydrogen; Hydrogen-Ion Concentration; Indomethacin; Phenylbutazone; Stomach Ulcer; Tablets, Enteric-Coated | 1972 |
Effects of the non-steroidal antiphlogistics on the gastric mucosal barrier and hexosamine content in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Transport; Carboxylic Acids; Chlorine; Cyclohexanes; Depression, Chemical; Gastric Mucosa; Hexosamines; Hydrogen; Indenes; Indomethacin; Male; Phenylacetates; Phenylbutazone; Potassium; Rats; Sodium; Stimulation, Chemical; Stomach Ulcer; Stress, Physiological | 1972 |
[Ulcers of the gastroduodenal tract due to drugs. Apropos of a personal experience].
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Aspirin; Duodenal Ulcer; Female; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Middle Aged; Phenylbutazone; Stomach Ulcer | 1972 |
Chondrocalcinosis articularis (pseudogout syndrome).
Topics: Adrenal Cortex Hormones; Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Calcinosis; Calcium Phosphates; Cartilage, Articular; Chondrocalcinosis; Colchicine; Crystallization; Diagnosis, Differential; Female; Gout; Humans; Indomethacin; Joint Diseases; Male; Middle Aged; Phenylbutazone; Radiography; Synovial Fluid; Uric Acid | 1973 |
[The treatment of chronic inflammatory rheumatism].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Collagen Diseases; Gold; Hot Temperature; Humans; Immunosuppressive Agents; Indomethacin; Phenylbutazone; Physician-Patient Relations; Psychotherapy; Rheumatic Diseases; Spondylitis, Ankylosing; Streptococcal Infections; Synovectomy | 1973 |
Preventive and curative effects of non-steroidal anti-inflammatory drugs on experimental peritoneal inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Capillary Permeability; Coloring Agents; Indomethacin; Male; Mefenamic Acid; Mice; Peritonitis; Phenylacetates; Phenylbutazone; Proteins | 1973 |
[Effect of aspirin and indomethacin on human gastric mucosa].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Gastric Mucosa; Humans; Indomethacin; Middle Aged; Rheumatic Diseases | 1973 |
Naproxen. Proceedings from an International Medical Symposium presented by Syntex Corporation 7-8 May 1973, Geneva, Switzerland.
Topics: Adolescent; Adult; Aged; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Drug Evaluation, Preclinical; Female; Gout; Humans; Indomethacin; Male; Methyl Ethers; Middle Aged; Naphthalenes; Osteoarthritis; Pain, Postoperative; Pregnancy; Propionates; Rheumatic Diseases; Spondylitis, Ankylosing | 1973 |
Observations on drug prescribing in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Drug Prescriptions; Dyspepsia; Family Practice; Female; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Scotland | 1974 |
Prevention of antiinflammatory drug-induced gastric lesions in rats by Abbott-29590.
Topics: Analgesics; Animals; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Gastric Juice; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Phenylbutazone; Premedication; Pyridines; Rats; Thiazines; Time Factors | 1974 |
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esophagoscopy; Gastritis; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Gastroscopy; Glycols; Humans; Indomethacin; ortho-Aminobenzoates; Phenylbutazone; Pyrazoles; Quinolines; Salicylates; Stomach Ulcer | 1974 |
Pharmacology of a new non-steroidal anti-inflammatory agent 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one (W-2395).
Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoxazines; Blood Pressure; Carrageenan; Diuretics; Edema; Electroencephalography; Gastrointestinal Hemorrhage; Heart Rate; Indomethacin; Male; Oxazines; Oxazoles; Phenylbutazone; Rats; Stomach Ulcer | 1974 |
Gastrointestinal blood loss caused by tolmetin, aspirin, and indomethacin.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Benzoates; Chromium Radioisotopes; Diet; Female; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Melena; Pyrroles; Time Factors | 1974 |
Letter to the editor: Non steroid anti-inflammatory drugs and pregnancy.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Female; Fetus; Homeostasis; Humans; Indomethacin; Mixed Function Oxygenases; Multienzyme Complexes; Postpartum Hemorrhage; Pregnancy; Prostaglandin Antagonists; Time Factors | 1974 |
Antagonism of cholera enterotoxin by anti-inflammatory agents in the rat.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Body Weight; Cholera; Dexamethasone; Disease Models, Animal; Enterotoxins; Ethacrynic Acid; Female; Indomethacin; Injections, Subcutaneous; Phenylbutazone; Prednisolone; Rats; Rats, Inbred Strains; Sodium Salicylate | 1972 |
Studies on phagocytosis. II. The effect of nonsteroidal anti-inflammatory drugs on phagocytosis and on urate crystal-induced canine joint inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Carbon Isotopes; Dogs; Dose-Response Relationship, Drug; Foreign-Body Reaction; Indomethacin; Inflammation; Injections, Intra-Articular; Injections, Intravenous; Joint Diseases; Kinetics; Leukocytes; Phagocytosis; Phenylbutazone; Rabbits; Serum Albumin, Radio-Iodinated; Starch; Uric Acid | 1972 |
Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol).
Topics: Acetaminophen; Animals; Aspirin; Brain; Dogs; In Vitro Techniques; Indomethacin; Ligases; Prostaglandins; Rabbits; Spleen | 1972 |
Aspirin and indomethacin prolong parturition in rats: evidence that prostaglandins contribute to expulsion of fetus.
Topics: Administration, Oral; Animals; Aspirin; Biological Assay; Chickens; Chromatography, Thin Layer; Female; Fetal Death; Gestational Age; Indomethacin; Muscle Contraction; Obstetric Labor Complications; Postpartum Hemorrhage; Pregnancy; Prostaglandins; Rats; Uterus | 1972 |
Delay of parturition in the rat by anti-inflammatory agents which inhibit the biosynthesis of prostaglandins.
Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Cortisone; Depression, Chemical; Female; Fetal Death; Gestational Age; Indomethacin; Injections, Intraperitoneal; Obstetric Labor Complications; Obstetric Labor, Premature; Pregnancy; Prostaglandins; Rats; Thiazoles | 1972 |
Effect of synthetic gonadotrophin-releasing hormone (Gn-RH) on ovulation blockade by aspirin and indomethacin.
Topics: Adrenal Glands; Animals; Aspirin; Depression, Chemical; Drug Interactions; Female; Gonadotropins, Equine; Hypothalamus; Indomethacin; Luteinizing Hormone; Organ Size; Ovulation; Ovum; Phenobarbital; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Prostaglandins; Radioimmunoassay; Rats; Time Factors; Uterus | 1972 |
Hemodynamic effects of small amounts of endotoxin in the bovine.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Cattle; Endotoxins; Escherichia coli; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Indomethacin; Oxygen; Pulmonary Circulation; Time Factors | 1973 |
Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats.
Topics: Acetaminophen; Animals; Aspirin; Body Temperature; Cats; Cerebral Ventricles; Chromatography, Thin Layer; Cisterna Magna; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Prostaglandins; Pyrogens; Shigella dysenteriae | 1973 |
Proceedings: The usefulness of homologous pairs of rabbit skin grafts for studying the pharmacology of anti-rheumatic agents.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Fluocinolone Acetonide; Indomethacin; Organ Size; Phenylbutazone; Rabbits; Skin Transplantation; Transplantation, Homologous | 1974 |
Interaction between 'sensitized lymphocytes' and antigen in vitro. V. Vascular permeability induced by skin-reactive factor.
Topics: Aminocaproates; Animals; Antigens; Aprotinin; Aspirin; Blood Coagulation Tests; Capillary Permeability; Cell Migration Inhibition; Cells, Cultured; Esters; Guinea Pigs; Heparin; Hydrocortisone; Immunization; Indomethacin; Inflammation; Isoflurophate; Kymography; Lymph Nodes; Lymphocytes; Mercuribenzoates; Muscle, Smooth; Mycobacterium tuberculosis; Phenylbutazone; Protamines; Skin Tests; Thiocarbamates; Triprolidine; Trypsin Inhibitors | 1972 |
Inhibitors of Forssman guinea pig "anaphylaxis".
Topics: Aminophylline; Anaphylaxis; Animals; Antibody Formation; Aspirin; Blood Pressure; Carrageenan; Cromolyn Sodium; Female; Forssman Antigen; Guinea Pigs; Histamine; Immune Sera; Indomethacin; Lung; Male; Phenylephrine; Pressure; Rabbits; Serotonin | 1973 |
Studies on the mode of action of non-steroid anti-inflammatory drugs.
Topics: Animals; Aspirin; Cell Movement; Disease Models, Animal; Indomethacin; Inflammation; Leukocytes; Mefenamic Acid; Phenylbutazone; Prostaglandins; Rats; Time Factors | 1972 |
[Optimal therapy for rheumatoid arthritis in the Peoples' Republic of Poland].
Topics: Arthritis, Rheumatoid; Aspirin; Cyclophosphamide; Gold; Health Resorts; Humans; Indomethacin; Penicillamine; Phenylbutazone; Poland; Prednisone; State Medicine; Time Factors | 1972 |
Inhibition of prostaglandin synthesis in man.
Topics: Aspirin; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Deuterium; Female; Humans; Hydroxylamines; Indomethacin; Male; Mass Spectrometry; Prostaglandins; Sex Factors; Sodium Salicylate; Tritium | 1972 |
Platelet factor-4--properties and clinical significance.
Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Fibrin; Freezing; Glomerulonephritis; Heparin Antagonists; Humans; Indomethacin; Microcirculation; Serotonin | 1972 |
[Therapy of chronic polyarthritis. 2].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Betamethasone; Dexamethasone; Flufenamic Acid; Humans; Indomethacin; Methylprednisolone; Oxyphenbutazone; Paramethasone; Phenylbutazone; Prednisolone; Prednisone; Triamcinolone | 1972 |
The prostaglandins: biology and biochemistry.
Topics: Aspirin; Blood Platelets; Bone and Bones; Cardiovascular System; Digestive System; Eye; Fatty Acids, Essential; Female; Humans; Indomethacin; Kidney; Lung; Male; Ovary; Prostaglandins; Semen; Skin; Uterus | 1972 |
Induced optical activity following the binding of warfarin, indomethacin, 4-hydroxycoumarin and salicylic acid to human serum albumin.
Topics: Aspirin; Binding Sites; Circular Dichroism; Coumarins; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Protein Binding; Salicylates; Serum Albumin; Warfarin | 1972 |
A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents.
Topics: Adrenochrome; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Cattle; Cyclization; Fatty Acids, Unsaturated; Flufenamic Acid; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Indomethacin; Male; Mefenamic Acid; Multienzyme Complexes; Naphthols; Oxygenases; Phenylbutazone; Propionates; Prostaglandins; Seminal Vesicles; Spectrophotometry | 1972 |
Aspirin and indomethacin abolish thyrotropin-induced increase in thyroid cell prostaglandins.
Topics: Animals; Aspirin; Cattle; Immune Sera; In Vitro Techniques; Indomethacin; Prostaglandins; Rabbits; Radioimmunoassay; Stimulation, Chemical; Thyroid Gland; Thyrotropin | 1972 |
[Gastric erosions and ulcerations in gastritis caused by drugs].
Topics: Aminopyrine; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastritis; Gastroscopy; Glucocorticoids; Humans; Indomethacin; Penicillins; Phenylbutazone; Stomach Ulcer; Suppositories | 1972 |
Adverse reaction profiles of drug eruptions.
Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Erythema Multiforme; Humans; Indomethacin; International Cooperation; Oxyphenbutazone; Oxytetracycline; Phenylbutazone; Photosensitivity Disorders; Skin Diseases; Stevens-Johnson Syndrome; Tetracycline; World Health Organization | 1972 |
Ovulation blockade by aspirin or indomethacin--in vivo evidence for a role of prostaglandin in gonadotrophin secretion.
Topics: Animals; Aspirin; Biological Assay; Cattle; Cross Reactions; Depression, Chemical; Female; Gonadotropins, Equine; Hypothalamus; Immune Sera; Indomethacin; Luteinizing Hormone; Organ Size; Ovulation; Pituitary Gland; Prostaglandins; Rabbits; Radioimmunoassay; Rats; Serum Albumin, Bovine; Time Factors; Uterus | 1972 |
The Berry Lecture. Studies of the gastric mucosal barrier--its relevance to clinical gastric disease.
Topics: Animals; Aspirin; Dogs; Epithelium; Female; Gastric Mucins; Gastric Mucosa; Gastritis; Humans; Hydrogen; Hypotension; Indomethacin; Lithium; Middle Aged; Permeability; Prednisolone; Rabbits; Stomach Ulcer; Stress, Physiological; Taurocholic Acid | 1972 |
Influence of some drugs on platelet aggregation: a study in hypertensive patients.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Blood Cell Count; Blood Coagulation; Blood Platelets; Dimethylamines; Dipyridamole; Humans; Hypertension; In Vitro Techniques; Indazoles; Indomethacin; Phenylbutazone; Platelet Adhesiveness; Reserpine; Thrombosis; Time Factors | 1972 |
Effect of non-steroid anti-inflammatory drugs on prostaglandin biosynthesis by skin.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Female; In Vitro Techniques; Indomethacin; Inflammation; Prostaglandins; Rats; Skin | 1973 |
Interactions between prostaglandin E 1 and calcium at the level of the mitochondrial membrane.
Topics: Animals; Aspirin; Calcium; Calcium Isotopes; Drug Interactions; Energy Transfer; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Manganese; Membranes; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Prostaglandins; Rats; Strontium; Time Factors; Tritium | 1973 |
Aspirin and indomethacin: effect on instillation-abortion time of mid-trimester hypertonic saline induced abortion.
Topics: Abortion, Induced; Adult; Amniotic Fluid; Aspirin; Depression, Chemical; Drug Interactions; Female; Humans; Hypertonic Solutions; Indomethacin; Oxytocin; Pregnancy; Punctures; Sodium Chloride; Time Factors | 1973 |
Analgesics and other drugs for relief of pain.
Topics: Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Indomethacin; Methadone; Morphine; Narcotics; Pain; Pentazocine; Pyrazoles; Salicylates; Substance-Related Disorders | 1973 |
Displacement of thiopental from plasma proteins by nonsteroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Binding, Competitive; Blood Proteins; Carbon Isotopes; Indomethacin; Male; Mefenamic Acid; Naphthaleneacetic Acids; Phenylbutazone; Protein Binding; Rabbits; Rats; Sleep; Thiopental; Time Factors; Ultrafiltration | 1973 |
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
Topics: Animals; Aspirin; Blood; Complement System Proteins; Dogs; Histamine; Humans; In Vitro Techniques; Indomethacin; Mice; Neoplasms; Prostaglandins; Rats | 1973 |
Delayed manifestation of ultraviolet reaction in the guinea-pig caused by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Body Weight; Erythema; Guinea Pigs; Indomethacin; Permeability; Phenylbutazone; Prednisolone; Radiation Effects; Skin; Skin Absorption; Time Factors; Ultraviolet Rays | 1973 |
Effect of steroidal and nonsteroidal anti-inflammatory compounds in a milkweed-sap-induced rat pedal edema.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Chlorpromazine; Cyproheptadine; Dexamethasone; Dose-Response Relationship, Drug; Edema; Enterobacteriaceae; Hindlimb; Hydrocortisone; Indomethacin; Male; Phenylbutazone; Plant Extracts; Plants; Promethazine; Rats; Time Factors | 1973 |
[Bronchial asthma, a side effect of indomethacin which can be avoided].
Topics: Adult; Aspirin; Asthma; Humans; Indomethacin; Male; Nasal Polyps | 1973 |
Non-steroidal anti-inflammatory drugs: effects on the utilization of glucose and production of lactic acid in tissue culture.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Barbiturates; Cells, Cultured; Chick Embryo; Flufenamic Acid; Glucose; Indomethacin; Lactates; Mefenamic Acid; Phenylbutazone | 1973 |
Duration of inhibition of platelet prostaglandin formation and aggregation by ingested aspirin or indomethacin.
Topics: Adult; Aspirin; Blood Platelets; Depression, Chemical; Epinephrine; Humans; Indomethacin; Platelet Adhesiveness; Prostaglandins; Time Factors | 1973 |
Indomethacin and aspirin inhibition of prostaglandin E2 synthesis by sheep seminal vesicles microsome powder.
Topics: Animals; Arachidonic Acids; Aspirin; Chromatography, Thin Layer; Depression, Chemical; In Vitro Techniques; Indomethacin; Male; Microsomes; Powders; Prostaglandins; Seminal Vesicles; Sheep; Tritium | 1973 |
[Influence of various drugs on the tissue permeability. 7. Effect of anti-inflammatory drugs on the changes in mucopolysaccharase activity in inflamed tissues of filter paper-implanted rats].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Enzyme Activation; Female; Flufenamic Acid; Glucuronidase; Glycoside Hydrolases; Hexosaminidases; Indomethacin; Inflammation; Muramidase; Phenylbutazone; Prednisolone; Rats; Time Factors | 1973 |
Tinnitus as an indication of therapeutic serum salicylate levels.
Topics: Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Audiometry; Drug Tolerance; Humans; Indomethacin; Middle Aged; Salicylates; Spectrophotometry; Time Factors; Tinnitus | 1973 |
Effect of nonsteroid anti-inflammatory and antipyretic drugs on prostaglandin biosynthesis by human skin.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Chloroquine; Culture Media; Female; Humans; In Vitro Techniques; Indomethacin; Prostaglandins; Skin; Tritium | 1973 |
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors | 1973 |
The antihypertensive action of arachidonic acid in the spontaneous hypertensive rat and its antagonism by anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Blood Pressure; Heart Rate; Indomethacin; Male; Phenylbutazone; Prostaglandins; Rats | 1973 |
The inhibition by aspirin and indomethacin of osteolytic tumor deposits and hypercalcaemia in rats with Walker tumour, and its possible application to human breast cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Calcium Radioisotopes; Carcinoma 256, Walker; Female; Humans; Hydrogen-Ion Concentration; Hypercalcemia; Indomethacin; Lactates; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Time Factors | 1973 |
[Gold therapy and agranulocytosis].
Topics: Adult; Agranulocytosis; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzyl Compounds; Collagen; Dimethylamines; Erythrocytes; Female; Gold; Half-Life; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Indazoles; Indomethacin; Male; Mice; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Synovial Fluid; Thiosulfates; Triaziquone | 1973 |
Aspirin and other cross-reacting small chemicals in known aspirin intolerant patients.
Topics: Analgesics; Antioxidants; Aspirin; Asthma; Blood Coagulation; Cross Reactions; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Tolerance; Humans; Hypnotics and Sedatives; Indomethacin; Pharmaceutic Aids; Phenacetin; Rhinitis; Urticaria | 1973 |
The treatment of gout.
Topics: Acute Disease; Allopurinol; Aspirin; Colchicine; Drug Therapy, Combination; Gout; Indomethacin; Phenylbutazone; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1973 |
The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A potent non-steroidal anti-inflammatory drug.
Topics: Acetaminophen; Adjuvants, Immunologic; Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Sedimentation; Carrageenan; Erythrocytes; Fluorine; Indomethacin; Mycobacterium; Propionates; Rats; Time Factors; Yeasts | 1973 |
[Anti-complement activity in vitro and in vivo of some non-steroid anti-inflammatory drugs].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Complement Inactivator Proteins; Flufenamic Acid; Hemolysis; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Rabbits | 1973 |
[Indomethacin in complex treatment of infectious nonspecific polyarthritis in children].
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Butadienes; Child; Child, Preschool; Drug Therapy, Combination; Humans; Hydrocortisone; Indomethacin | 1973 |
[Pharmacological studies of N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F1). 3. Interaction with proteins].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Benzyl Compounds; Blood Proteins; Cell Membrane; Chemical Phenomena; Chemistry; Erythrocytes; Female; Flufenamic Acid; Guinea Pigs; Hemolysis; Indazoles; Indomethacin; Male; Mefenamic Acid; Mice; Phenylbutazone; Phenylenediamines; Protease Inhibitors; Protein Binding; Protein Denaturation; Pyrazoles; Pyridoxal Phosphate; Rats; Serum Albumin, Bovine | 1973 |
[Interaction of antirheumatic agents with proteolytic enzymes].
Topics: Analgesics; Aspirin; Chloroquine; Chymotrypsin; In Vitro Techniques; Indomethacin; Phenylbutazone; Prednisolone; Trypsin Inhibitors | 1973 |
[Drug-induced gastritis].
Topics: Aminopyrine; Anti-Bacterial Agents; Anticoagulants; Aspirin; Biopsy; Gastric Mucosa; Gastritis; Humans; Indomethacin; Phenylbutazone; Reserpine; Sulfonamides | 1973 |
[Childhood rheumatoid arthritis with an acute course].
Topics: Acute Disease; Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Female; Gold; Humans; Immunoglobulin A; Immunoglobulin M; Indomethacin; Infant; Male; Rheumatoid Factor | 1973 |
Back diffusion of hydrogen ions across gastric mucosa of patients with gastric ulcer and rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Biological Transport, Active; Cell Membrane Permeability; Chlorides; Diffusion; Female; Gastric Mucosa; Humans; Hydrogen; Hydrogen-Ion Concentration; Indomethacin; Male; Middle Aged; Osmolar Concentration; Potassium; Prednisone; Sodium; Stomach Ulcer; Wound Healing | 1974 |
An enzymatic mechanism for the antithrombotic and antihemostatic actions of aspirin.
Topics: Arachidonic Acids; Aspirin; Blood Coagulation Factors; Blood Platelets; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Indomethacin; Mixed Function Oxygenases; Platelet Adhesiveness; Prostaglandins | 1974 |
Studies of anti-inflammatory drugs and aliphatic alcohols on antral mucosa.
Topics: 1-Propanol; Alcohols; Animals; Anti-Inflammatory Agents; Aspirin; Biological Transport, Active; Butanols; Chlorides; Cortisone; Dogs; Ethanol; Gastric Mucosa; Glucose; Hydrogen-Ion Concentration; Hypertonic Solutions; Indomethacin; Membrane Potentials; Methanol; Phenylbutazone; Potassium; Pyloric Antrum; Sodium | 1974 |
Inhibition of the lymphocyte-mediated cytotoxic reaction by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cytotoxicity Tests, Immunologic; Hydrocortisone; Immunity, Cellular; In Vitro Techniques; Indomethacin; Lymphocytes; Male; Phenylbutazone; Rats | 1974 |
Indomethacin estimation in plasma and serum by electron capture gas chromatography.
Topics: Aspirin; Chemical Phenomena; Chemistry; Chromatography, Gas; Drug Interactions; Electrons; Humans; Indomethacin; Methods | 1974 |
The influence of psychotropic drugs on prostaglandin biosynthesis.
Topics: Animals; Antidepressive Agents; Aspirin; Carbon Radioisotopes; Cell-Free System; Chlorpromazine; Chromatography, Thin Layer; Depression, Chemical; Desipramine; Doxepin; Guinea Pigs; Indomethacin; Lung; Methods; Pargyline; Phenelzine; Promazine; Prostaglandins; Tranylcypromine | 1974 |
Reiter's syndrome.
Topics: Adult; Africa; Arthritis, Reactive; Asia; Aspirin; Child, Preschool; Diagnosis, Differential; Dysentery, Bacillary; Enteritis; Europe; Female; Gonorrhea; Humans; Indomethacin; Male; Radiography; Skin Diseases; Steroids; Synovitis; Urinary Tract Infections | 1974 |
[On pharmacological clinical studies of the effectiveness of non-steroid anti-inflammatory agents in rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Evaluation Studies as Topic; Humans; Indomethacin; Phenylbutazone | 1974 |
Upper gastrointestinal disease in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arizona; Arthritis, Rheumatoid; Aspirin; Drug Therapy, Combination; Duodenal Ulcer; Female; Gastric Juice; Gold; Humans; Hydrogen-Ion Concentration; Indomethacin; Male; Middle Aged; Peptic Ulcer; Phenylbutazone; Sex Factors; Stomach Ulcer | 1974 |
[Antiphlogistic pharmacotherapy with non-steroid drugs].
Topics: Aminopyrine; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Indomethacin; Phenylbutazone | 1974 |
Treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chloroquine; Cyclophosphamide; Female; Gold; Humans; Hydroxychloroquine; Indomethacin; Male; Middle Aged; Phenylbutazone; Physical Therapy Modalities; Rest | 1974 |
Letter: Indomethacin, aspirin, and urticaria.
Topics: Adult; Aspirin; Humans; Indomethacin; Male; Spondylitis, Ankylosing; Urticaria | 1974 |
Release of neutral protease and beta-glucuronidase from human neutrophils in the presence of cartilage treated with various immunologic reactants.
Topics: Allopurinol; Arthritis, Rheumatoid; Aspirin; Cartilage; Chloroquine; Colchicine; Factor VIII; Glucuronidase; Hot Temperature; Humans; Immunoglobulin G; Indomethacin; Iodine Radioisotopes; L-Lactate Dehydrogenase; Methylprednisolone; Neutrophils; Peptide Hydrolases; Probenecid; Protein Denaturation; Sulfur Radioisotopes; Synovial Fluid; Triamcinolone Acetonide; Vinblastine | 1974 |
The binding of urate to plasma proteins.
Topics: Allopurinol; Aspirin; Binding Sites; Blood Proteins; Colchicine; Dialysis; Evaluation Studies as Topic; Gout; Humans; Hydrogen-Ion Concentration; Indomethacin; Kidney Diseases; Kinetics; Methods; Osmolar Concentration; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Solubility; Sulfinpyrazone; Temperature; Time Factors; Uric Acid | 1974 |
Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts.
Topics: Animals; Aspirin; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Heart; Hydrogen-Ion Concentration; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Prostaglandins; Rabbits; Rats; Receptors, Adrenergic | 1974 |
The effects of various naturally occurring cannabinoids on hypotonic-hyperthermic lysis of rat erythrocytes.
Topics: Animals; Aspirin; Cannabis; Cell Membrane; Dose-Response Relationship, Drug; Dronabinol; Erythrocytes; Hemolysis; Hot Temperature; In Vitro Techniques; Indomethacin; Osmolar Concentration; Phenylbutazone; Rats | 1974 |
Inhibition of sheep vesicular gland oxygenase by unsaturated fatty acids from skin of essential fatty acid deficient rats.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Chromatography, Thin Layer; Fatty Acids, Essential; Fatty Acids, Unsaturated; Indomethacin; Male; Oxygen Consumption; Oxygenases; Prostaglandins; Rats; Seminal Vesicles; Sheep; Skin; Time Factors | 1974 |
Effect of nonsteroidal anti-inflammatory drugs in endotoxin shock.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Depression, Chemical; Dogs; Endotoxins; Escherichia coli; Indomethacin; Kinins; Phenylbutazone; Shock, Septic | 1968 |
[Effect of some anti-inflammatory drugs on the ATP-content and cell proliferation of neoplastic mast cells in vitro].
Topics: Adenosine Triphosphate; Amides; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Benzimidazoles; Benzoates; Cell Division; Chloroquine; Culture Techniques; Depression, Chemical; Dinitrophenols; Indomethacin; Mast-Cell Sarcoma; Methotrexate; Naphthalenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Salicylamides; Sodium Salicylate; Stimulation, Chemical | 1968 |
Effects in vivo and in vitro of nonsteroidal anti-inflammatory drugs on (rat stomach) histidine decarboxylase.
Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Carboxy-Lyases; Fasting; Female; Flufenamic Acid; Hydroxylamines; Indomethacin; Male; Mast-Cell Sarcoma; Mice; Phenylbutazone; Rats; Stomach | 1969 |
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Azaguanine; Azathioprine; Bacteria; Benzimidazoles; Depression, Chemical; Edema; Enterococcus faecalis; Flufenamic Acid; Fungi; Indomethacin; Lactobacillus; Mefenamic Acid; Mercaptopurine; Oxyphenbutazone; Phenylbutazone; Purines; Pyrimethamine; Rats; Riboflavin; Salicylates; Staphylococcus; Tetracycline; Thioguanine | 1970 |
Analgetic drugs--the mild analgetics.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Analgesics; Aspirin; Codeine; Dextropropoxyphene; Hemorrhage; Humans; Indomethacin; Morphinans; Pain; Phenacetin; Phenylbutazone; Substance-Related Disorders | 1972 |
Anti-inflammatory and other properties of 2,3-dihydrol-1-H-pyridino-(2,3- b) (1,4)-thiazine-2-one; ABBott-29590.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dogs; Edema; Fever; Gastric Mucosa; Guinea Pigs; Indomethacin; Ketones; Lethal Dose 50; Male; Mice; Motor Activity; Muscle, Smooth; Phenylbutazone; Pyridines; Rats; Thiazines | 1972 |
[Therapeutic trends in osteoarthrosis].
Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Aspirin; Calcium; Humans; Indomethacin; Osteoarthritis; Physical Therapy Modalities | 1972 |
Effect of anti-arthritic drugs on sulfhydryl reactivity of rat serum.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoates; Chemical Phenomena; Chemistry; Ethylmaleimide; Gold; Indomethacin; Kinetics; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Salts; Spectrophotometry; Sulfhydryl Compounds; Time Factors | 1972 |
The inhibition of goldthioglucose and bipiperidyl mustard-induced hypothalamic lesions by anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atropine; Chlorpromazine; Glucose; Gold; Heparin; Hydrocortisone; Indomethacin; Male; Mice; Mustard Compounds; Pyrogallol; Salicylates; Sodium Chloride | 1972 |
Lysosome membrane stabilization in vivo: effects of steroidal and nonsteroidal anti-inflammatory drugs on the integrity of rat liver lysosomes.
Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Chlorpheniramine; Chlorpromazine; Cyclophosphamide; Dextropropoxyphene; Flufenamic Acid; Glucosidases; Hydrocortisone; In Vitro Techniques; Indomethacin; Kinetics; Liver; Lysosomes; Mefenamic Acid; Membranes; Osmotic Fragility; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats; Steroids; Vitamin A | 1972 |
Antipyretics.
Topics: Acetaminophen; Analgesics; Aspirin; Child; Health Education; Humans; Indomethacin; Mefenamic Acid; Pediatrics; Phenacetin; Salicylamides; Seizures; Substance-Related Disorders | 1972 |
Relationship between inhibition of prostaglandin synthesis and drug efficacy: support for the current theory on mode of action of aspirin-like drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Carbon Isotopes; Cattle; Chromatography, Thin Layer; Indomethacin; Male; Microsomes; Naphthalenes; Propionates; Prostaglandins; Seminal Vesicles; Stereoisomerism | 1972 |
Evaluation of vulneray activity by an open wound procedure in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Ascorbic Acid; Aspirin; Depression, Chemical; Female; Hydrocortisone; Indomethacin; Male; Oxandrolone; Phenylbutazone; Rats; Skin; Stimulation, Chemical; Testosterone; Vitamin A; Wound Healing; Zinc | 1972 |
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid; Glucocorticoids; Granuloma; Indomethacin; Lethal Dose 50; Male; Mice; Phenylbutazone; Pyrroles; Rats; Rats, Inbred Strains; Triamcinolone Acetonide | 1972 |
Prostaglandin production by mouse fibrosarcoma cells in culture: inhibition by indomethacin and aspirin.
Topics: Adrenal Glands; Animals; Antigens; Aspirin; Borohydrides; Clone Cells; Culture Media; Fibroblasts; Fibrosarcoma; HeLa Cells; Humans; Hydrogen-Ion Concentration; Immune Sera; Indomethacin; Mice; Models, Biological; Neuroblastoma; Neuroglia; Prostaglandins; Radioimmunoassay; Rats; Tritium | 1972 |
In vitro effect of anti-inflammatory agents on phagocytosis and bacterial killing by human neutrophilic leukocytes.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; Humans; Hydrocortisone; Indomethacin; Mefenamic Acid; Neutrophils; Phagocytosis; Phenacetin; Phenylbutazone; Staphylococcus; Stimulation, Chemical | 1972 |
Release of lysosomal enzymes in experimental inflammations: effects of anti-inflammatory drugs.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Carrageenan; Dexamethasone; Edema; Female; Glucuronidase; Hexosaminidases; Indomethacin; Inflammation; Lysosomes; Methotrexate; Nystatin; Phenylbutazone; Prednisolone; Rats; Time Factors | 1972 |
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gold; Humans; Hydroxychloroquine; Indomethacin; Oxyphenbutazone; Phenylbutazone; Prednisone | 1972 |
Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters.
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Arthritis; Aspirin; Body Weight; Cyclophosphamide; Disease Models, Animal; Freund's Adjuvant; Hindlimb; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Muramidase; Phenylbutazone; Prednisolone; Rats | 1971 |
The influence of anti-inflammatory and immunosuppressant drugs on Nystatin induced oedema.
Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Arthritis; Aspirin; Azathioprine; Chloramphenicol; Cyclophosphamide; Dexamethasone; Drug Antagonism; Edema; Hydrocortisone; Immunosuppressive Agents; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Nystatin; Phenylacetates; Phenylbutazone; Prednisolone; Rats; Rifampin; Triamcinolone | 1971 |
New light on inflammation.
Topics: Animals; Aspirin; Blood Vessels; Dogs; Humans; Indomethacin; Inflammation; Prostaglandins; Rats; Skin; Stimulation, Chemical | 1971 |
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Female; Granuloma; Hindlimb; Hydrocortisone; Indomethacin; Lethal Dose 50; Mefenamic Acid; Naphthalenes; Pain; Phenylbutazone; Propionates; Rats; Spasm | 1971 |
[Assessment of analgesic actions of narcotic antagonists, with special reference to nociception induced by retrograde injection of bradykinin into the carotid artery of rats].
Topics: Acetates; Aminopyrine; Analgesics; Animals; Aspirin; Bradykinin; Carotid Arteries; Chlorpromazine; Codeine; Indomethacin; Injections, Intra-Arterial; Levallorphan; Male; Methods; Methotrimeprazine; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain; Pentazocine | 1971 |
Effects of anti-inflammatory drugs on the stability of rat liver lysosomes in vitro.
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Flufenamic Acid; Fluorine; Glucuronidase; Hydrocortisone; Hydroxychloroquine; In Vitro Techniques; Indomethacin; Liver; Lysosomes; Male; Membranes; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats | 1971 |
Dissimilar effects of anti-inflammatory drugs on stability of lysosomes from peritoneal and circulating leukocytes and liver.
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Exudates and Transudates; Flufenamic Acid; Glucuronidase; Hydrocortisone; Hydroxychloroquine; In Vitro Techniques; Indomethacin; Leukocytes; Liver; Lysosomes; Male; Membranes; Oxyphenbutazone; Paramethasone; Peritoneal Cavity; Phenylbutazone; Rabbits; Rats | 1971 |
Wy 23205, a new non-steroidal anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Bradykinin; Gastrointestinal Diseases; Guinea Pigs; Hindlimb; In Vitro Techniques; Indomethacin; Inflammation; Oxazoles; Phenylbutazone; Propionates; Rats | 1971 |
On the paw edema induced by subcutaneous injection of minute glass particles in the rat.
Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Extremities; Glass; Indomethacin; Irritants; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Suspensions; Time Factors | 1971 |
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Carrageenan; Cyproheptadine; Drug Combinations; Edema; Erythema; Flufenamic Acid; Fluorine; Granuloma; Guinea Pigs; Hindlimb; Hydrocortisone; Indomethacin; Male; Morphine; Organ Size; Phenolphthaleins; Phenylbutazone; Pressure; Rats; Sulfonamides; Thymus Gland | 1971 |
Stimulation and blockade of prostaglandin biosynthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Endocrine Glands; Enzyme Activation; Indomethacin; Kinetics; Oxygen Consumption; Oxygenases; Phenanthrolines; Phenols; Polarography; Prostaglandins; Sheep; Time Factors | 1971 |
Descriptive functions in disease.
Topics: Aspirin; Biometry; Diagnosis; Humans; Indomethacin; Mathematics; Models, Biological; Spondylitis, Ankylosing | 1971 |
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Carrageenan; Edema; Indomethacin; Leukocytes; Macrophages; Male; Mefenamic Acid; Methotrexate; Phagocytosis; Phenylbutazone; Pleurisy; Radiation Effects; Rats; Thymidine; Tritium; Turpentine | 1971 |
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone | 1971 |
[Evaluation of a practical use of synthetic antimalarials in the treatment of rheumatoid polyarthritis].
Topics: Aged; Antimalarials; Arthritis, Rheumatoid; Aspirin; Chloroquine; Eye Diseases; Female; Follow-Up Studies; Humans; Hydroxychloroquine; Indomethacin; Male; Middle Aged; Oxyphenbutazone; Prednisone | 1971 |
The conservative management of rheumatoid arthritis.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Exercise Therapy; Hot Temperature; Humans; Indomethacin; Orthopedic Equipment; Rest | 1971 |
Approaches to the patient with degenerative joint disease.
Topics: Adrenal Cortex Hormones; Aspirin; Exercise Therapy; Hip Joint; Hot Temperature; Humans; Indomethacin; Knee Joint; Massage; Osteoarthritis; Osteotomy; Phenylbutazone; Silicones; Traction | 1971 |
The effect of N,N,N'-tetramethylazoformamide (TMAF) on lysosomal stability in the presence and absence of anti-inflammatory agents.
Topics: Acid Phosphatase; Adenosine Triphosphate; Amides; Animals; Anti-Inflammatory Agents; Aspirin; Azo Compounds; Chloroquine; Drug Antagonism; Flufenamic Acid; Formamides; Glucuronidase; Hexosaminidases; Hydrocortisone; In Vitro Techniques; Indomethacin; Liver; Lysosomes; Male; Mefenamic Acid; Membranes; Phenylbutazone; Rats; Sulfatases | 1971 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
[Comparative study on the ulcerogenous effect of various antiphlogistic agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Female; Gastric Mucosa; Indomethacin; Prednisone; Rats; Stomach Ulcer | 1971 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histamine; Humans; Indomethacin; Middle Aged; Nasal Polyps; Reflex; Rhinitis; Skin Manifestations; Vasodilator Agents | 1967 |
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
Topics: Animals; Arachidonic Acids; Aspirin; Biological Assay; Chromatography, Thin Layer; Colon; Guinea Pigs; Indomethacin; Lung; Prostaglandins; Rats; Salicylates; Stomach | 1971 |
Indomethacin and aspirin abolish prostaglandin release from the spleen.
Topics: Animals; Aspirin; Biological Assay; Chickens; Colon; Dogs; Epinephrine; Female; Indomethacin; Male; Organ Size; Perfusion; Prostaglandins; Rats; Rectum; Spleen; Stomach | 1971 |
Dissociation between platelet factor 3 availability and platelet aggregation.
Topics: Absorption; Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Glycolysis; Humans; Indomethacin; Oxidative Phosphorylation; Platelet Adhesiveness; Purpura, Thrombocytopenic; Spectrum Analysis; Thromboplastin; Time Factors | 1971 |
Diaryloxazole and diarylthiazolealkanoic acids: two novel series of non-steroidal anti-inflammatory agents.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Carrageenan; Edema; Gastric Mucosa; Gastrointestinal Hemorrhage; Hot Temperature; Humans; Indomethacin; Oxazoles; Phenylbutazone; Protein Denaturation; Rats; Serum Albumin; Thiazoles | 1968 |
Fever responses to bacterial pyrogens in guinea pigs and application for screening of antipyretic agents.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Body Temperature; Female; Fever; Flufenamic Acid; Guinea Pigs; Indomethacin; Injections, Intravenous; Lipopolysaccharides; Phenacetin; Phenylbutazone; Polysaccharides, Bacterial; Pseudomonas; Pyrogens; Quinine; Typhoid-Paratyphoid Vaccines | 1968 |
Synovial fluid and serological changes ater treatment in arthritic diseases.
Topics: Acid Phosphatase; Antibodies, Antinuclear; Arthritis; Aspirin; Autoantibodies; Humans; Indomethacin; Phenylbutazone; Steroids; Synovial Fluid | 1968 |
Palindromic rheumatism: case report with response to indomethacin.
Topics: Adult; Arthritis; Aspirin; Colchicine; Finger Joint; Humans; Indomethacin; Knee; Male; Metacarpus; Phenylbutazone; Rheumatic Diseases | 1969 |
[Medical therapeutic management of chronic inflammatory rheumatism].
Topics: Adrenal Cortex Hormones; Antimalarials; Antineoplastic Agents; Arthritis, Rheumatoid; Aspirin; Chronic Disease; Gold Colloid, Radioactive; Humans; Immunosuppressive Agents; Indomethacin; Pyrazoles; Rheumatic Diseases; Salicylates; Ultrasonic Therapy | 1969 |
[Changes in the gastric mucosa by peroral antirheumatic drugs].
Topics: Anti-Inflammatory Agents; Antipyrine; Aspirin; Gastric Acidity Determination; Gastric Mucosa; Humans; Indomethacin; Phenylbutazone; Prednisone; Rheumatic Diseases; Stomach Diseases | 1969 |
Investigation of the carrageenin-induced rat paw edema assay and correlation between anti-inflammatory activity and gastric hemorrhage production in the rat.
Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Croton Oil; Edema; Gastrointestinal Hemorrhage; Hydrocortisone; Indomethacin; Phenylbutazone; Rats | 1970 |
[Pharmacotherapy in rheumatic diseases].
Topics: Adrenal Cortex Hormones; Analgesics; Antimalarials; Antineoplastic Agents; Aspirin; Female; Gold; Humans; Indomethacin; Male; Phenylbutazone; Rheumatic Diseases | 1971 |
Measurement of arthritic pain and effects of analgesics in the adjuvant-treated rat.
Topics: Adjuvants, Immunologic; Aminopyrine; Analgesics; Animals; Arthritis; Aspirin; Female; Hydrocortisone; Indomethacin; Mefenamic Acid; Morphine; Pain; Phenylbutazone; Pyrazoles; Rats; Salicylamides | 1971 |
Effect of drugs on the hemolysis of rat erythrocytes.
Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Desoxycorticosterone; Digitalis Glycosides; Diuretics; Erythrocytes; Glucose; Guanethidine; Hemolysis; Hydrocortisone; Hypotonic Solutions; Indomethacin; Levorphanol; Male; Neostigmine; Rats; Tripelennamine | 1969 |
[Preliminary research on the activity of anti-inflammatory drugs in arthritis induced b adjuvant in rats].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Betamethasone; Chloroquine; Freund's Adjuvant; Indomethacin; ortho-Aminobenzoates; Phenylbutazone; Rats | 1969 |
[Effect of non-steroid anti-inflammatory drugs for osteoarthritis of the knee; PSP clearance test].
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Female; Humans; Indomethacin; Knee Joint; Male; Middle Aged; Phenolphthaleins; Phenylbutazone | 1969 |
Effect of drugs on the binding of urate to human albumin.
Topics: Allopurinol; Aspirin; Colchicine; Humans; Indomethacin; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Sulfinpyrazone; Uric Acid | 1970 |
[Current analgesic anti-inflammatory drugs].
Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal Diseases; Humans; Indomethacin; Inflammation; Lysosomes; ortho-Aminobenzoates; Peptic Ulcer; Pyrazoles; Salicylates | 1970 |
Effect of acetylsalicylic acid, other nonsteroidal anti-inflammatory agents, and dipyridamole on human blood platelets.
Topics: Adenine Nucleotides; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Carbon Isotopes; Centrifugation; Connective Tissue; Dipyridamole; Drug Synergism; Epinephrine; Flufenamic Acid; Humans; Indomethacin; Mefenamic Acid; Phenylbutazone; Serotonin; Sodium Salicylate; Sulfinpyrazone | 1970 |
Effect of some uricosuric and anti-inflammatory drugs on the binding of uric acid to human serum albumin in vitro.
Topics: Allopurinol; Anti-Inflammatory Agents; Aspirin; Binding Sites; Caprylates; Colchicine; Dialysis; Fluorescence; Humans; In Vitro Techniques; Indomethacin; Mefenamic Acid; Phenylbutazone; Probenecid; Protein Binding; Serum Albumin; Sodium Salicylate; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1970 |
[Effect of aspirin and indocin on the course of influenza virus infection in mice].
Topics: Animals; Aspirin; Culture Techniques; Indomethacin; Mice; Orthomyxoviridae; Orthomyxoviridae Infections | 1970 |
Effects of antirheumatic drugs on human erythrocyte membranes.
Topics: Aminobenzoates; Analgesics; Antipyrine; Aspirin; Barbiturates; Benzoates; Cell Membrane; Erythrocytes; Flufenamic Acid; Hemolysis; Hot Temperature; Humans; Indomethacin; Mefenamic Acid; Oxyphenbutazone; Phenylbutazone; Sodium Salicylate; Time Factors | 1970 |
Interactions of anti-inflammatory drugs in carrageenan-induced foot edema of the rat.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Female; Foot Diseases; Hydrocortisone; Indomethacin; Phenylbutazone; Rats | 1970 |
Interaction between aspirin and indomethacin in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Drug Antagonism; Feces; Humans; Indomethacin; Time Factors | 1970 |
A comparison of an effect of different anti-inflammatory drugs on human platelets.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Epinephrine; Female; Humans; Indomethacin; Male; Middle Aged; Platelet Adhesiveness; Salicylates | 1970 |
Inhibitory effects of indomethacin, aspirin and certain other drugs on inflammations induced in rat and dog by carrageenan, sodium urate and ellagic acid.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrans; Carrageenan; Cellulose; Dogs; Indomethacin; Inflammation; Knee Joint; Neutrophils; Pain; Pressure; Rats; Sodium; Species Specificity; Sulfates; Synovial Fluid; Uric Acid | 1970 |
Activation of trypsin by anti-inflammatory drugs.
Topics: Aminocaproates; Aminosalicylic Acids; Anti-Inflammatory Agents; Aspirin; Butyrates; Chymotrypsin; Cortisone; Dexamethasone; Drug Synergism; Flufenamic Acid; Indomethacin; Phenylbutazone; Thrombin; Trypsin | 1970 |
[Experimental ophthalmic anti-inflammatory activity of some steroid and non-steroid drugs topically applied].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Eye; Eye Diseases; Glucocorticoids; Indomethacin; Inflammation; Ophthalmic Solutions; ortho-Aminobenzoates; Phenylbutazone; Rabbits | 1970 |
Indomethacin-induced intestinal lesions in the rat.
Topics: Administration, Oral; Animals; Antacids; Aspirin; Atropine; Bile Ducts; Bretylium Compounds; Chlorpromazine; Cholestyramine Resin; Cyproheptadine; Food Deprivation; Indomethacin; Injections, Subcutaneous; Intestinal Diseases; Intestinal Fistula; Intestinal Perforation; Intestine, Small; Male; Pentobarbital; Peptic Ulcer; Phenylbutazone; Rats; Scopolamine; Starvation; Time Factors | 1970 |
Inhibition of human granulocyte elastase by gold sodium thiomalate.
Topics: Anti-Inflammatory Agents; Aspirin; Gold; Humans; Hydrocortisone; In Vitro Techniques; Indomethacin; Leukocytes; Pancreatic Elastase; Phenylbutazone; Sodium; Succinates; Thiomalates | 1970 |
[Influence of various drugs on the tissue permeability. 5. Comparison of the potency of various anti-inflammatory agents by the dermal tissue permeability test using filter paper implanted subcutaneously in the ventral region of rats].
Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Azepines; Bromelains; Chloroquine; Cortisone; Cyclohexanecarboxylic Acids; Cyproheptadine; Depression, Chemical; Dexamethasone; Female; Flufenamic Acid; Granuloma; Hydrocortisone; Indomethacin; Injections, Subcutaneous; Mefenamic Acid; Methods; Permeability; Phenylbutazone; Prednisolone; Rats; Skin; Time Factors | 1970 |
Management of juvenile rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; Chloroquine; Exercise Therapy; Gold; Humans; Indomethacin; Phenylbutazone; Prednisone; Rest; Splints; Uveitis, Anterior | 1970 |
Mode of stabilizing action of non-steroid anti-inflammatory drugs on erythrocyte membrane.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Cell Membrane; Dogs; Erythrocytes; Flufenamic Acid; Hemolysis; Hot Temperature; Hydrogen-Ion Concentration; Indomethacin; Lysophosphatidylcholines; Nitrobenzenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Phospholipases; Protein Denaturation; Pyrazoles; Salicylates; Saponins; Serum Albumin, Bovine; Sulfates; Surface-Active Agents | 1970 |
Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
Topics: Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antibody Formation; Aspirin; Blood Platelets; Blood Proteins; Cell Aggregation; Cyclophosphamide; Depression, Chemical; Fibrinolysis; Flufenamic Acid; Glucuronidase; Guinea Pigs; Hemolysis; Hydrocortisone; Indomethacin; Inflammation; Male; Mefenamic Acid; Mice; Phenylbutazone; Protein Binding; Protein Denaturation; Pyridines; Rabbits; Rats; Stimulation, Chemical | 1970 |
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried | 1970 |
Xylose test: effect of aspirin and indomethacin.
Topics: Administration, Oral; Aspirin; Creatinine; Depression, Chemical; Gastrointestinal Motility; Glomerular Filtration Rate; Humans; Indomethacin; Injections, Intravenous; Intestinal Absorption; Kidney; Xylose | 1971 |
Factors influencing the inhibitory action of anti-inflammatory drugs on carrageenin induced oedema.
Topics: Administration, Oral; Animals; Aspirin; Carrageenan; Edema; Female; Hindlimb; Humidity; Indomethacin; Injections, Intraperitoneal; Intestinal Absorption; Phenylbutazone; Rats; Temperature | 1971 |
Anti-inflammatory and analgesic properties of clonixin (2-(2' methyl-3' chloro anilino) nicotinic acid).
Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Flufenamic Acid; Guinea Pigs; Indomethacin; Nicotinic Acids; Pain; Peptic Ulcer; Phenylbutazone; Plethysmography, Impedance; Rats | 1971 |
Current evaluation of drugs for treating arthritis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Codeine; Cortisone; Cyclophosphamide; Dextropropoxyphene; Gold; Gout; Humans; Indomethacin; Mefenamic Acid; Pentazocine; Phenylbutazone; Salicylates; Spondylitis, Ankylosing | 1971 |
Mode of action of antirheumatic drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Bilirubin; Binding Sites; Blood Proteins; Chloroquine; Female; Gold; Humans; Indomethacin; Jaundice; Male; Middle Aged; Phenylbutazone; Prednisolone; Pregnancy; Protein Binding; Tryptophan | 1971 |
Anti-inflammatory and liver sulfhydryl content-altering effects of certain nonsteroids in the rat.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Chlorpromazine; Cyproheptadine; Edema; Indomethacin; Liver; Male; Phenylbutazone; Rats; Semicarbazides; Sparteine; Sulfhydryl Compounds; Tetrabenazine | 1971 |
Response of aspirin-allergic patients to challenge by some analgesics in common use.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged; Spirometry | 1971 |
[On the effect of the combination of acetylsalicyclic acid with indomethacin in rheumatic pain].
Topics: Adult; Aged; Aspirin; Drug Synergism; Female; Humans; Indomethacin; Joint Diseases; Male; Middle Aged; Neuralgia | 1967 |
[Antagonism of non-narcotic analgesics to the release of plasma kinins by B. jararaca venom and pancreatic kallikrein].
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Antivenins; Arteries; Aspirin; Blood Pressure; Bradykinin; Drug Synergism; Female; Hypotension; Indomethacin; Kallikreins; Male; Pancreas; Phenylacetates; Phenylbutazone; Rabbits; Rats; Snakes; Trypsin | 1967 |
Comparative evaluation of the antipyretic activity in normothermic and pyrexial mice, rats, and guinea-pigs.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Body Temperature; Guinea Pigs; Indomethacin; Male; Mice; Phenacetin; Phenylbutazone; Rats | 1967 |
Mucopolysaccharides in synovial fluid. Effect of aspirin and indomethacin on hyaluronic acid.
Topics: Adult; Aged; Aspirin; Female; Humans; Hyaluronic Acid; Indomethacin; Male; Middle Aged; Synovial Fluid | 1968 |
Further studies on the erythrocyte anti-inflammatory assay.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Dimethyl Sulfoxide; Erythrocytes; Estrogens; Ethanol; Flufenamic Acid; Hemolysis; In Vitro Techniques; Indomethacin; Orphenadrine; Oxyphenbutazone; Phenylbutazone; Sodium Salicylate; Steroids | 1968 |
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial Spasm; Capillary Permeability; Carrageenan; Edema; Erythema; Gossypium; Granuloma; Guinea Pigs; Hydroxybutyrates; Indomethacin; Male; Mice; Phenylbutazone; Phenylbutyrates; Rats; Ultraviolet Rays | 1968 |
The assay of anti-pyretic drugs in mice, using intracerebral injection of pyretogenins.
Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Biological Assay; Body Temperature; Cerebral Ventricles; Female; Fever; Flufenamic Acid; Indomethacin; Injections; Male; Mefenamic Acid; Methods; Mice; Phenylacetates; Phenylbutazone; Pyrogens; Rabbits; Typhoid-Paratyphoid Vaccines | 1968 |
[Contribution to subsepsis hyperergica (Wissler)].
Topics: Anti-Bacterial Agents; Aspirin; Humans; Indomethacin; Penicillin G Benzathine; Penicillins; Prednisone; Streptomycin; Wissler's Syndrome | 1968 |
Suppression of enzyme release from isolated rat liver lysosomes by non-steroidal anti-inflammatory drugs.
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Centrifugation; Cortisone; Depression, Chemical; Female; Flufenamic Acid; Fluorine; Glucuronidase; Indomethacin; Liver; Lysosomes; Mitochondria, Liver; ortho-Aminobenzoates; Phenylbutazone; Rats | 1968 |
[Clinical evaluation of non-steroid anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Flufenamic Acid; Humans; Indomethacin; Inflammation; ortho-Aminobenzoates; Phenylbutazone | 1968 |
Action of antiinflammatory drugs on the lysozyme activity and "turbidity" of serum from rats with adjuvant arthritis or endocrine deficiency.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Proteins; Edema; Freund's Adjuvant; Hindlimb; Hot Temperature; Hypophysectomy; Indomethacin; Lysosomes; Male; Muramidase; Paramethasone; Phenylbutazone; Protein Denaturation; Rats; Spectrophotometry; Starch; Stress, Physiological | 1969 |
Separation and fractionation of hyaluronic acid from human synovial fluid on agarose gels.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Colorimetry; Densitometry; Humans; Hyaluronic Acid; Indomethacin; Methods; Polysaccharides; Prednisone; Proteins; Synovial Fluid | 1969 |
Management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health Personnel; Barbiturates; Chlordiazepoxide; Chloroquine; Exercise Therapy; Gold; Hospitalization; Hot Temperature; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Mechlorethamine; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Prednisolone; Rest | 1969 |
Neck and shoulder pain: evaluation and conservative management.
Topics: Aspirin; Braces; Bursitis; Cryosurgery; Diagnosis, Differential; Electromyography; Ethyl Chloride; Exercise Therapy; Female; Hot Temperature; Humans; Indomethacin; Massage; Middle Aged; Muscles; Neck; Orthopedic Equipment; Pain; Palpation; Phenylbutazone; Physical Therapy Modalities; Procaine; Shoulder; Spasm; Steroids; Traction | 1969 |
Biphasic development of carrageenin edema in rats.
Topics: Animals; Aspirin; Body Temperature; Carrageenan; Edema; Foot; Hydrocortisone; Indomethacin; Male; Phenylbutazone; Rats; Skin; Time Factors | 1969 |
Arthritis: the team approach.
Topics: Arthritis; Aspirin; Colchicine; Gout; Government Agencies; Humans; Indomethacin; Occupational Therapy; Orthopedics; Patient Care Team; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Psychiatry; United States; Voluntary Health Agencies | 1969 |
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Edema; Flufenamic Acid; Foot Diseases; Gold; Indoles; Indomethacin; Penicillamine; Phenylbutazone; Pleural Effusion; Rats | 1969 |
Polyamide layer chromatography of some antipyretics.
Topics: Acetanilides; Amides; Aminopyrine; Analgesics; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Indomethacin; Oxyphenbutazone; Phenacetin; Salicylates | 1969 |
[Comparison of some antiphlogistics in the systems of neoplastic cells].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Membrane Permeability; Cell-Free System; Chloroquine; Creatine Kinase; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Flufenamic Acid; Indomethacin; Nucleic Acids; Nucleosides; Oxyphenbutazone; Phenylbutazone; Protein Biosynthesis; RNA Nucleotidyltransferases; RNA, Neoplasm; Stimulation, Chemical | 1969 |
Gold therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Chloroquine; Gold; Humans; Hydroxychloroquine; Indomethacin; Phenylbutazone | 1965 |
Control of fever in Hodgkin's disease by indomethacin.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Female; Fever; Hodgkin Disease; Humans; Indomethacin; Male; Mechlorethamine; Middle Aged; Pruritus | 1965 |
The antipyretic effect of indomethacin: a clinical study of the use for fever states in man.
Topics: Adolescent; Analgesics; Aspirin; Child; Child, Preschool; Humans; Indomethacin; Infant | 1966 |
Effect of anti-inflammatory agents on acute experimental synovitis in dogs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chlorpromazine; Codeine; Dogs; Gout; Hydrocortisone; Indomethacin; Models, Theoretical; Phenylbutazone; Promazine; Synovitis; Uric Acid | 1966 |
Comparative effect of antirheumatic drugs on adjuvant-induced polyarthritis in rats.
Topics: Animals; Arthritis; Aspirin; Chloroquine; Hydroxychloroquine; Indomethacin; Male; Mycobacterium; Phenylbutazone; Prednisolone; Rats | 1966 |
Treatment of adjuvant arthritis in rats with anti-inflammatory drugs.
Topics: Aminocaproates; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dexamethasone; Dimethyl Sulfoxide; Flufenamic Acid; Freund's Adjuvant; Indomethacin; Mefenamic Acid; ortho-Aminobenzoates; Phenylbutazone; Quinolines; Rats | 1966 |
An extended study of indomethacin. II. Clinical therapy.
Topics: Adolescent; Adult; Arthritis; Arthritis, Rheumatoid; Aspirin; Child; Female; Gout; Humans; Indomethacin; Male; Phenylbutazone; Probenecid; Psoriasis; Spondylitis, Ankylosing | 1966 |
Effect of non-steroidal anti-inflammatory drugs in the Evans Blue pleural effusion.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coloring Agents; Flufenamic Acid; Indomethacin; Mefenamic Acid; ortho-Aminobenzoates; Phenylbutazone; Pleural Effusion; Rats | 1966 |
A method for differentiating nonspecific irritants from anti-inflammatory agents using the carrageenin abscess test.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Croton Oil; Formaldehyde; Hydrocortisone; Indomethacin; Irritants; Kaolin; Mefenamic Acid; ortho-Aminobenzoates; Phenylbutazone; Rats | 1966 |
[Effect of non-narcotic analgesics on hypotension due to bradykinin].
Topics: Aminopyrine; Animals; Aspirin; Blood Pressure; Bradykinin; Hypotension; Indomethacin; Phenylbutazone; Rabbits | 1966 |
[Drug therapy of chronic polyarthritis].
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Chloroquine; Disability Evaluation; Glucocorticoids; Gold; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Prednisolone | 1966 |
[Clinical and hematological observations on patients with rheumatoid arthritis during indomethacin therapy].
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Cell Count; Blood Platelets; Blood Sedimentation; Erythrocyte Count; Female; Humans; Indomethacin; Leukocyte Count; Male; Middle Aged; Prothrombin Time; Serotonin Antagonists | 1966 |
Presence of a general irritation and inhibition of a local inflammation.
Topics: Acetates; Animals; Aspirin; Blood; Carrageenan; Coloring Agents; Edema; Female; Formaldehyde; Hypertonic Solutions; Ileum; Indomethacin; Inflammation; Phenylbutazone; Rats; Sodium Chloride; Stomach; Yeasts | 1966 |
Bronchial asthma induced by indomethacin.
Topics: Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis | 1967 |
Effect of locally applied anti-inflammatory substances on rat skin wounds.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Cortisone; Hydrocortisone; Indomethacin; Male; Methylprednisolone; Phenylbutazone; Rats; Skin; Wound Healing | 1967 |
Medical management of patients with disability due to arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Antimalarials; Arthritis, Infectious; Arthritis, Rheumatoid; Aspirin; Child; Female; Gold; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Middle Aged; Orthopedics; Osteoarthritis; Phenylbutazone; Prednisone | 1967 |
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides | 1967 |
Effect of certain nonsteroid antirheumatic drugs on active amino acid transport across the small intestine.
Topics: Animals; Aspirin; Biological Transport, Active; Cricetinae; Dinitrophenols; In Vitro Techniques; Indomethacin; Intestine, Small; Male; Phenylbutazone; Rats; Salicylates; Tryptophan | 1967 |
Method for the determination of acetylsalicylic acid in the blood.
Topics: Aspirin; Barbiturates; Dextropropoxyphene; Glutethimide; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Indomethacin; Meprobamate; Salicylamides; Salicylates; Spectrophotometry | 1967 |
Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukocytes; Leukotriene B4; Masoprocol; Neutrophils; Pyrazoles | 1984 |
[Recent discoveries in the field of mediators of anti-inflammation: leukotrienes].
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arachidonic Acids; Aspirin; Humans; Indomethacin; Inflammation; Leukotriene B4; Muscle, Smooth; Oxidation-Reduction; SRS-A | 1984 |
Platelet-facilitated adhesion of SV40-3T3 cells to collagen.
Topics: Adult; Animals; Aspirin; Blood Platelets; Cell Adhesion; Cell Transformation, Viral; Collagen; Humans; Indomethacin; Mice; Simian virus 40 | 1984 |
Platelet accumulation on collagen: drugs which inhibit arachidonic acid metabolism and affect intracellular cyclic AMP levels.
Topics: Alprostadil; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Prostaglandins E; Thromboxanes | 1984 |
Inhibition of neutrophil activation by nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cell Aggregation; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Prostaglandin Antagonists; Superoxides; Thiazines | 1984 |
Gastrointestinal erosions and the lack of inflammatory response.
Topics: Animals; Aspirin; Chemotactic Factors; Gastric Mucosa; Gastroenteritis; Indomethacin; Intestinal Mucosa; Peptic Ulcer; Rats | 1980 |
Activity ratio between antiprostacyclin and antiaggregating effects of acetylsalicylic acid, indometacin and ditazole.
Topics: Animals; Aorta; Aspirin; Epoprostenol; In Vitro Techniques; Indomethacin; Male; Oxazoles; Platelet Aggregation; Prostaglandin Antagonists; Rabbits | 1980 |
Relationship between spasmogenic activity of bombesin and prostaglandins on the rat pylorus.
Topics: Animals; Aspirin; Bombesin; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Peptides; Prostaglandins; Pylorus; Rats; Somatostatin | 1980 |
"In vivo" effects of acetylsalicylic acid and two ether derived compounds on primary immune response and lymphoblastic transformation.
Topics: Acetanilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Female; Hemagglutinins; Immunity; Immunosuppressive Agents; Indomethacin; Lymphocyte Activation; Mice; Salicylates; Thymidine | 1980 |
C5a-induced aortic contraction: effect of an antihistamine and inhibitors of arachidonate metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Complement C5; Complement C5a; Cyclooxygenase Inhibitors; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular | 1982 |
Prostaglandin E1 receptors on chick embryo myoblasts.
Topics: Alprostadil; Animals; Aspirin; Cell Aggregation; Cell Fusion; Chick Embryo; Indomethacin; Kinetics; Muscles; Prostaglandins E; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tunicamycin | 1981 |
Release of a slow-reacting substance from rabbit platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Platelets; Chromatography, High Pressure Liquid; Cysteine; Indomethacin; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1981 |
In vitro effect of acetylcholine and bethanechol on the contractions of the human detrusor muscle. Influence of prostaglandins.
Topics: Acetylcholine; Adult; Aged; Aspirin; Bethanechol Compounds; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Tonus; Neurotransmitter Agents; Physostigmine; Prostaglandins; Urinary Bladder | 1982 |
[Mechanisms regulating the release of deaggregating prostanoids].
Topics: Adrenergic beta-Antagonists; Almitrine; Angiotensins; Animals; Arachidonic Acids; Aspirin; Atropine; Captopril; Cats; Cells, Cultured; Choline; Drug Interactions; Epoprostenol; Female; Indomethacin; Male; Piperazines; Platelet Aggregation; Prostaglandins; Prostaglandins E; Saralasin; Stimulation, Chemical | 1982 |
Effects of aspirin, indomethacin, flufenamic acid and paracetamol on prostaglandin output from rat stomach and renal papilla in-vitro and ex-vivo.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Female; Flufenamic Acid; Gastric Mucosa; In Vitro Techniques; Indomethacin; Kidney Medulla; Prostaglandins E; Rats | 1983 |
Enhancement of hemopoietic stem cell proliferation by prostaglandin inhibitory drugs.
Topics: Acetaminophen; Animals; Aspirin; Bone Marrow Transplantation; Female; Flufenamic Acid; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Indomethacin; Mice; Mice, Inbred Strains; Organ Size; Prostaglandin Antagonists; Radiation Chimera; Spleen | 1983 |
The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dexamethasone; Dinoprostone; Exudates and Transudates; Fatty Acids, Unsaturated; Indomethacin; Inflammation; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Prostaglandins E; Pyrazoles; Rats; Thromboxane B2 | 1983 |
Suppression of laxative action of phenolphthalein by orally-administered indomethacin or aspirin.
Topics: Administration, Oral; Animals; Aspirin; Cathartics; Indomethacin; Male; Mice; Phenolphthaleins | 1984 |
Interrelationships of SRS-A production and arachidonic acid metabolism in human lung tissue.
Topics: Antigens; Arachidonic Acids; Aspirin; Catechols; Histamine Release; Humans; Indomethacin; Lung; Masoprocol; Pyrazoles; SRS-A | 1980 |
Effects of indomethacin, aspirin, and fat-free diet on experimental pancreatitis in the rat.
Topics: Amylases; Animals; Aspirin; Body Weight; Deoxycholic Acid; Dietary Fats; Female; Indomethacin; Pancreatitis; Rats; Sodium Chloride | 1980 |
[Current status of medical treatment].
Topics: Aminophylline; Animals; Anticoagulants; Aspirin; Barbiturates; Brain Ischemia; Cerebrovascular Disorders; Dextrans; Epoprostenol; Glucose; Glycerol; Heparin; Humans; Indomethacin; Pentoxifylline; Sulfinpyrazone | 1980 |
[Effect of aspirin and indomethacin on the immunological release of histamine and slow reacting substance of anaphylaxis (SRS-A) from guinea-pig lung tissues (author's transl)].
Topics: Animals; Aspirin; Guinea Pigs; Histamine Release; In Vitro Techniques; Indomethacin; Lung; Male; SRS-A | 1980 |
Studies on the role of cyclic GMP in the control of human platelet function.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acids; Aspirin; Blood Platelets; Cyclic GMP; Humans; Indomethacin | 1980 |
Lipid metabolism during mediator release from mast cells: studies of the role of arachidonic acid metabolism in the control of phospholipid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Aspirin; Cattle; Dose-Response Relationship, Drug; Histamine Release; Indomethacin; Kinetics; Lipid Metabolism; Male; Mast Cells; Myeloma Proteins; Phospholipids; Rats | 1981 |
Control mechanisms of histamine release from human basophils in vitro: the role of phospholipase A2 and of lipoxygenase metabolites.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Basophils; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Histamine Release; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase; Meclofenamic Acid; Phospholipases; Phospholipases A; Phospholipases A2 | 1981 |
Factors determining the site of chronic gastroduodenal ulcers.
Topics: Animals; Aspirin; Chronic Disease; Diet; Digestive System; Duodenum; Gastric Acid; Gastric Mucins; Gastric Mucosa; Gastritis; Humans; Indomethacin; Ischemia; Muscle Contraction; Peptic Ulcer; Phenylbutazone | 1982 |
Interferon enhancement of natural killer cell cytotoxicity: role of cyclic nucleotides.
Topics: Animals; Aspirin; Calcium; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Indomethacin; Interferons; Killer Cells, Natural; Lymphocytes; Mice; Mice, Inbred BALB C; Time Factors | 1982 |
Indomethacin and aspirin do not inhibit the antiviral or anti-proliferative actions of interferon.
Topics: Animals; Aspirin; Cell Division; Cell Line; Encephalomyocarditis virus; Indomethacin; Interferons; Leukemia L1210; Vesicular stomatitis Indiana virus; Virus Replication | 1982 |
[Interaction of polymorphonuclear leukocytes, bradykinin and carragenin. Transference reaction in the rat].
Topics: Animals; Aspirin; Bradykinin; Carrageenan; Drug Synergism; Edema; Indomethacin; Neutrophils; Phospholipases A; Phospholipases A2; Prostaglandins; Rats; Rats, Inbred Strains | 1982 |
Effects of C5a on guinea pig lung: histamine release and mechanism of contraction.
Topics: Animals; Aspirin; Atropine; Chromones; Complement C5; Complement C5a; Dose-Response Relationship, Immunologic; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth | 1983 |
[Pathophysiology of peptic ulcer].
Topics: Aspirin; Bile Acids and Salts; Gastric Acid; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrins; Histamine Release; Humans; Indomethacin; Mast Cells; Peptic Ulcer; Somatostatin | 1983 |
Antiviral activity of Wratizolin.
Topics: Animals; Antiviral Agents; Aspirin; Cells, Cultured; Dimethyl Sulfoxide; Female; Flufenamic Acid; Guinea Pigs; Herpes Genitalis; Indomethacin; Interferons; Male; Mefenamic Acid; Ribavirin; Simplexvirus; Thiazoles; Virus Replication | 1983 |
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1983 |
Biological activity of leukotriene C4 in guinea pigs: in vitro and in vivo studies.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Bradykinin; Epoprostenol; Guinea Pigs; Histamine; Indomethacin; Lung; Male; Muscle Contraction; SRS-A; Thromboxane A2; Trachea | 1982 |
Abrogation of suppressor cell function by inhibitors of prostaglandin synthesis.
Topics: Anemia, Hemolytic, Autoimmune; Animals; Aspirin; Autoantibodies; Cyclooxygenase Inhibitors; Dinoprostone; Erythrocytes; Female; Immunization, Passive; Indomethacin; Mice; Mice, Inbred Strains; Prostaglandins E; Rats; T-Lymphocytes; T-Lymphocytes, Regulatory | 1982 |
Flushing in rosacea: a possible mechanism.
Topics: Adult; Aspirin; Body Temperature; Bradykinin; Clonidine; Epinephrine; Face; Female; Humans; Indomethacin; Male; Methysergide; Middle Aged; Rosacea; Skin Temperature | 1982 |
Inhibition of the graft-versus-host response by BCGcw-induced suppressor cells or prostaglandin E1.
Topics: Animals; Aspirin; BCG Vaccine; Graft vs Host Disease; Graft vs Host Reaction; Immune Tolerance; Indomethacin; Mice; Prostaglandins E; Spleen; T-Lymphocytes, Regulatory | 1983 |
Pharmacology of thromboxane synthetase inhibitors.
Topics: Animals; Aspirin; Blood Platelets; Dogs; Epoprostenol; Guinea Pigs; Humans; Ibuprofen; Indomethacin; Kinetics; Lung; Methacrylates; Microsomes; Oxidoreductases; Thromboxane-A Synthase | 1983 |
Effect of prostaglandin synthesis inhibitors on basal and carbon dioxide-stimulated cerebral blood flow in man.
Topics: Adult; Arachidonic Acids; Aspirin; Carbon Dioxide; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Fatty Acids, Nonesterified; Female; Humans; Indomethacin; Male; Middle Aged; Naproxen; Platelet Aggregation | 1983 |
Effects of prostaglandin E2 inhibition on norepinephrine plasma levels after adrenergic stimulation in man.
Topics: Adult; Aspirin; Cold Temperature; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Indomethacin; Kinetics; Male; Norepinephrine; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Vascular Resistance | 1983 |
In vivo and in vitro effects of arachidonic acid products on liver cell integrity following carbon tetrachloride poisoning.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alanine Transaminase; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Tetrachloride Poisoning; Epoprostenol; Female; Indomethacin; Liver; Lysine; Peroxides; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
[Inhibition of prostaglandins in the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)].
Topics: Adult; Aged; Aspirin; Brain Diseases; Ethanol; Female; Humans; Inappropriate ADH Syndrome; Indomethacin; Lung Diseases; Male; Middle Aged; Prostaglandin Antagonists; Prostaglandins; Vasopressins; Water | 1983 |
Prostaglandins and angioplasty. An experimental study in canine arteries.
Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1983 |
Effect of medroxyprogesterone acetate and of some antiinflammatory agents on mouse erythroleukemia cell differentiation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Differentiation; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flurbiprofen; Indomethacin; Leukemia, Erythroblastic, Acute; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Pyrazoles; Time Factors | 1984 |
Studies with enterotoxigenic microorganisms: effects of candidate antidiarrhoeals in experimental animals in vivo.
Topics: Aluminum Hydroxide; Animals; Antidiarrheals; Aspirin; Bacterial Infections; Charcoal; Chlorpromazine; Cholestyramine Resin; Diarrhea; Drug Combinations; Enterotoxins; Indomethacin; Loperamide; Male; Niacinamide; Rats; Rats, Inbred Strains; Water-Electrolyte Balance | 1984 |
[Prevention of thrombosis by thrombocyte inhibitors. 1. Cell regulation mechanisms and pharmacological modification].
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cyclic AMP; Dextrans; Dipyridamole; Humans; Hydroxychloroquine; Indomethacin; Platelet Aggregation; Prostaglandins; Sulfinpyrazone; Thrombosis; Thromboxane A2 | 1980 |
Effect of some drugs on thromboplastin (factor III) activity of human monocytes in vitro.
Topics: Aspirin; Cyclic AMP; Dexamethasone; Glucuronidase; Humans; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Monocytes; Muramidase; Promethazine; Thromboplastin | 1980 |
Blockage of partially obstructed coronary arteries with platelet thrombi: comparison between its prevention with cyclooxygenase inhibitors versus prostacyclin.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Coronary Vessels; Cyclic AMP; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Ibuprofen; Indomethacin; Kinetics; Muscle Contraction; Platelet Aggregation; Prostaglandins | 1980 |
Effects of indomethacin, 5,8,11,14-eicosatetraynoic acid, and p-bromophenacyl bromide on lysosomal enzyme release and superoxide anion generation by human polymorphonuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Aspirin; Ethanol; Fatty Acids, Unsaturated; Glucuronidase; Humans; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Lysosomes; Neutrophils; Oxygen; Phospholipases; Phospholipases A; Superoxides | 1980 |
Lysosomal enzyme release from human granulocytes is inhibited by indomethacin, ETYA, and BPB.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Aspirin; Cyclooxygenase Inhibitors; Depression, Chemical; Exocytosis; Fatty Acids, Unsaturated; Glucuronidase; Granulocytes; Humans; Indomethacin; Lysosomes; Phospholipases A; Superoxides | 1980 |
Secretion of inflammatory mediators from synovial fibroblasts: dissociation of collagenase and prostaglandin release.
Topics: Animals; Aspirin; Cells, Cultured; Fibroblasts; Indomethacin; Microbial Collagenase; Prostaglandins E; Rabbits; Synovial Membrane; Tetradecanoylphorbol Acetate | 1980 |
Specific receptors for prostaglandins in airways.
Topics: Animals; Aspirin; Atropine; Bronchi; Cats; Epoprostenol; Female; Guinea Pigs; Histamine; Humans; Indomethacin; Isoproterenol; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Phentolamine; Propranolol; Prostaglandins E; Prostaglandins F; Pyrilamine; Receptors, Cell Surface; Receptors, Prostaglandin; Trachea | 1980 |
Prostaglandin receptor: induction of density changes in rat liver plasma membrane.
Topics: Animals; Aspirin; Cell Membrane; Indomethacin; Kinetics; Liver; Male; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Prostaglandin | 1980 |
Elevated levels of prostaglandin E2 in Yoshida hepatoma and the inhibition of tumour growth by non-steroidal anti-inflammatory drugs.
Topics: Animals; Arachidonic Acids; Aspirin; Cell Division; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Depression, Chemical; Indoles; Indomethacin; Liver Neoplasms, Experimental; Male; Prostaglandins E; Pyridines; Rats; Time Factors | 1980 |
Evidence that OH. production by human PMNs is related to prostaglandin metabolism.
Topics: Aspirin; Granulocytes; Humans; Hydrogen; Hydroxides; Hydroxyl Radical; Indomethacin; Neutrophils; Oxygen; Phagocytosis; Phenols; Prostaglandins; Zymosan | 1980 |
Do endogenous prostaglandins modulate noradrenergic transmission in the rat isolated perfused vas deferens?
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Electric Stimulation; Indomethacin; Male; Meclofenamic Acid; Norepinephrine; Perfusion; Prostaglandins E; Rats; Synaptic Transmission; Vas Deferens | 1980 |
Inhibitory effect of tiaramide of aggregation in vivo and on electrophoresis of rabbit platelets.
Topics: Adenosine Diphosphate; Animals; Aspirin; Benzothiazoles; Cyclic AMP; Depression, Chemical; Electrophoresis; Female; In Vitro Techniques; Indomethacin; Male; Piperazines; Platelet Aggregation; Platelet Count; Prostaglandin Endoperoxides; Rabbits; Thiazoles | 1980 |
A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Epinephrine; Fibrinogen; Humans; Indomethacin; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins A; Prostaglandins H; Receptors, Cell Surface; Thromboxanes | 1981 |
Endogenous prostacyclin contributes to the efficacy of a thromboxane synthetase inhibitor for preventing coronary artery thrombosis.
Topics: Acrylates; Animals; Aspirin; Blood Platelets; Coronary Disease; Cyclic AMP; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Female; Ibuprofen; Indomethacin; Male; Methacrylates; Oxidoreductases; Platelet Aggregation; Prostaglandins; Prostaglandins H; Thromboxane-A Synthase | 1981 |
Effects of stimulators and inhibitors on arachidonic acid metabolism in hepatoma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; Indomethacin; Liver Neoplasms; Prostaglandins; Rats; Sodium Salicylate; Thromboxane B2; Thromboxanes; Tryptophan | 1981 |
cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Fatty Acids, Unsaturated; Humans; Indomethacin; Kinetics; Neutrophils; Oxygen; Structure-Activity Relationship; Superoxides | 1981 |
Stimulatory effect of latex and zymosan particles on cyclic adenosine 3',5'-monophosphate content in human granulocytes.
Topics: Aminophylline; Aspirin; Cell Survival; Cells, Cultured; Cyclic AMP; Granulocytes; Humans; Indomethacin; Latex; Phagocytosis; Prostaglandins; Zymosan | 1981 |
Up-regulation of hepatic prostaglandin E receptors in vivo induced by prostaglandin synthesis inhibitors.
Topics: Adenylyl Cyclases; Animals; Aspirin; Cell Membrane; Dose-Response Relationship, Drug; Indomethacin; Liver; Male; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Time Factors | 1981 |
Relation of respiratory burst and arachidonate metabolism during phagocytosis by guinea pig alveolar macrophages.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Aspirin; Guinea Pigs; Indomethacin; Macrophage Activation; Macrophages; Oxygen Consumption; Phagocytosis; Superoxides; Zymosan | 1982 |
The effects of arachidonic acid, PGI2, and 6-keto-PGF1 alpha on cyclic nucleotide concentrations in a ventilated and artificially perfused isolated dog lung.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclic AMP; Cyclic GMP; Dogs; Epoprostenol; In Vitro Techniques; Indomethacin; Kinetics; Lung; Perfusion; Prostaglandins; Tranylcypromine | 1982 |
Cyclic AMP and the regulation of prostaglandin production by macrophages.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aspirin; Bucladesine; Calcimycin; Cholera Toxin; Cyclic AMP; Indomethacin; Kinetics; Macrophages; Prostaglandins; Rats; Verapamil | 1983 |
Reactive oxygen production, arachidonate metabolism and cyclic AMP in macrophages.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Bucladesine; Calcimycin; Cyclic AMP; Dinoprostone; Indomethacin; Kinetics; Luminescent Measurements; Macrophages; Oxygen; Prostaglandins E; Rats; Verapamil | 1983 |
Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice.
Topics: Adenoma; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; DNA; Female; Gastric Mucosa; Indomethacin; Liver; Lung Neoplasms; Mice; Mice, Inbred Strains; Rats | 1983 |
Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aspirin; Cannabinoids; Dronabinol; Guanosine Triphosphate; Indomethacin; Male; Mice; Mice, Inbred ICR; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine | 1983 |
Role of local prostaglandin synthesis in the modulation of proliferative activity of rat colonic epithelium.
Topics: Animals; Aspirin; Cell Division; Colon; Cyclic AMP; DNA; Epithelial Cells; Female; Indomethacin; Intestinal Mucosa; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angiotensin II; Animals; Aspirin; Cyclooxygenase Inhibitors; Dipyridamole; Dogs; Epoprostenol; Female; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phthalazines; Pyridazines; Renal Artery | 1983 |
Omega 6-oxygenation of 6, 9, 12-octadecatrienoic acid in human platelets.
Topics: Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; gamma-Linolenic Acid; Humans; Indomethacin; Linolenic Acids; Lipoxygenase | 1983 |
Alpha adrenergic stimulation modified prostaglandins release in vas deferens.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Indomethacin; Male; Methoxamine; Mice; Muscle Contraction; Phenoxybenzamine; Prostaglandins E; Prostaglandins F; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1983 |
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemolysis; Histamine; Indomethacin; Male; Muscle Contraction; Norepinephrine; Peptides; Pyrilamine; Tachyphylaxis | 1984 |
Inhibition of PG production by MDL 035, a new non-steroidal non-acidic anti-inflammatory compound, in rat gastric mucosa and inflammatory exudate.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Exudates and Transudates; Gastric Mucosa; Imidazoles; In Vitro Techniques; Indomethacin; Inflammation; Male; Naproxen; Prostaglandins; Prostaglandins E; Rats; Stomach Ulcer | 1984 |
Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery.
Topics: Aged; Animals; Aorta, Abdominal; Aortic Aneurysm; Aspirin; Blood Platelets; Cell Survival; Dogs; Epoprostenol; Female; Hemodynamics; Humans; Indomethacin; Intraoperative Period; Male; Platelet Aggregation; Platelet Count; Prostaglandins; Surgical Procedures, Operative; Thromboxanes | 1983 |
The stimulatory effect of prostacyclin (PGI2) on isolated rabbit and rat aorta is probably associated to the generation of a thromboxane A2 (TXA2) "like-material".
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Aspirin; Corticosterone; Epoprostenol; Imidazoles; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rabbits; Rats; Species Specificity; Thromboxane A2; Thromboxanes; Vasoconstriction | 1983 |
Comparison of aspirin and indomethacin pre-treatments on the responses to reduced renal artery pressure in conscious dogs.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Dogs; Indomethacin; Kidney; Prostaglandins; Renal Artery; Renal Circulation; Renin | 1983 |
Prostaglandin synthesis inhibitors and primary antibody response in experimental nephrotic syndrome.
Topics: Animals; Antibody-Producing Cells; Aspirin; Hemolytic Plaque Technique; Indomethacin; Isoantibodies; Male; Nephrotic Syndrome; Prostaglandin Antagonists; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; Serum Albumin | 1984 |
Stimulation of gastric prostaglandin synthesis by refeeding in the rat. Role in protection of gastric mucosa from damage.
Topics: Animals; Aspirin; Dinoprost; Eating; Epoprostenol; Evaluation Studies as Topic; Female; Gastric Mucosa; Indomethacin; Prostaglandins F; Pyloric Antrum; Rats; Rats, Inbred Strains; Stomach Ulcer; Time Factors | 1984 |
Idiopathic hypercalciuria associated with hyperreninemia and high urinary prostaglandin E.
Topics: Aspirin; Bartter Syndrome; Calcium; Humans; Hyperaldosteronism; Indomethacin; Infant; Male; Nephrocalcinosis; Polyuria; Prostaglandins E; Renin | 1984 |
Arachidonic acid metabolism in the murine eosinophil. III. Effect of nonsteroid anti-inflammatory drugs on lymphokine-directed eosinophil migration in vivo.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Catechols; Cell Migration Inhibition; Dose-Response Relationship, Drug; Eosinophils; Indomethacin; Lymphokines; Male; Masoprocol; Mice; Mice, Inbred CBA; Pyrazoles; Rats | 1983 |
Effect of prostaglandin synthesis inhibitors on basal and CO2-stimulated cerebral blood flow in man.
Topics: Arachidonic Acids; Aspirin; Carbon Dioxide; Cerebrovascular Circulation; Epoprostenol; Humans; In Vitro Techniques; Indomethacin; Naproxen; Platelet Aggregation; Prostaglandins | 1983 |
C3a-induced contraction of guinea pig lung parenchyma: role of cyclooxygenase metabolites.
Topics: Animals; Aspirin; Complement C3; Complement C3a; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Swine; Zymosan | 1983 |
Activation of blood coagulation in cancer: Trousseau's syndrome revisited.
Topics: Antibodies; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Platelets; Cell Adhesion; Cell Communication; Cyclooxygenase Inhibitors; Disseminated Intravascular Coagulation; Epoprostenol; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinopeptide A; Humans; Indomethacin; Monocytes; Neoplasm Transplantation; Neoplasms; Syndrome; Thrombocytopenia; Thrombocytosis; Thromboembolism; Thromboplastin | 1983 |
Effects of inhibitors of arachidonic acid metabolism and calcium entry on responses to acetylcholine, potassium and norepinephrine in the isolated canine saphenous vein.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium Channel Blockers; Dogs; Electric Stimulation; Female; Indomethacin; Kinetics; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Saphenous Vein | 1983 |
Effect of prostaglandin synthesis inhibitors on basal and carbon dioxide stimulated cerebral blood flow in man.
Topics: Adult; Arachidonic Acids; Aspirin; Carbon Dioxide; Cerebrovascular Circulation; Epoprostenol; Fatty Acids, Nonesterified; Female; Humans; Indomethacin; Male; Middle Aged; Naproxen; Oxygen; Oxygen Consumption; Platelet Aggregation; Prostaglandin Antagonists | 1983 |
Thromboxane A2 generation by the larval cestode, Taenia taeniaeformis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Horses; Imidazoles; Indomethacin; Kinetics; Larva; Platelet Aggregation; Rats; Taeniasis; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Suppression of lymphatic vessel contractility with inhibitors of arachidonic acid metabolism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; Dinoprost; Indomethacin; Lymphatic System; Muscle Contraction; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; SRS-A | 1983 |
Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Female; Guinea Pigs; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins; Pyrazoles; SRS-A; Zymosan | 1983 |
[Responses of isolated hepatic artery segments to barium in the presence of a flavonoid (4-methylesculetin), indomethacin and acetylsalicylate].
Topics: Animals; Aspirin; Barium; Hepatic Artery; Indomethacin; Lysine; Muscle Contraction; Scopoletin; Sheep; Umbelliferones | 1983 |
Salicylate fails to prevent the inhibitory effect of 5,8,11,14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid | 1983 |
In vitro contractile responses of the uterus from 'restricted diet' rats to adrenoceptor agonists. Influence of cyclo-oxygenase inhibitors.
Topics: Animal Feed; Animals; Aspirin; Cyclooxygenase Inhibitors; Diet; Estrus; Female; In Vitro Techniques; Indomethacin; Isoproterenol; Methoxamine; Norepinephrine; Pregnancy; Propranolol; Rats; Rats, Inbred Strains; Uterine Contraction; Uterus | 1983 |
Some properties of mouse platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Epoprostenol; Indomethacin; Lipoxygenase; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases | 1983 |
Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets.
Topics: Adult; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Indomethacin; Male; Platelet Aggregation; Sodium Salicylate; Thromboxane B2 | 1983 |
The metabolism of arachidonic acid in hamster lung microsomes is not completely inhibited by aspirin and indomethacin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Cricetinae; Female; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Lung; Mesocricetus; Microsomes; NADP; Prostaglandins | 1983 |
Fenflumizole: interactions with the arachidonic acid cascade.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Epoprostenol; Exudates and Transudates; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Inflammation; Male; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thromboxane A2 | 1983 |
Role of PGE2 in the modulation of the adrenergic response in man.
Topics: Adult; Aspirin; Cold Temperature; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Indomethacin; Lysine; Male; Norepinephrine; Prostaglandins E; Prostaglandins F; Sympathetic Nervous System; Vascular Resistance | 1983 |
A functional cyclooxygenase enzyme is not required for mediation of the pleiotropic effects of human alpha or beta interferon.
Topics: Aspirin; Breast Neoplasms; Cell Line; Female; Fibroblasts; Humans; Indomethacin; Interferon Type I; Killer Cells, Natural; Male; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Viral Interference; Vulvar Neoplasms | 1983 |
Stimulatory effect of lymphocytes from Chagas' patients on spontaneously beating rat atria.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Catechols; Chagas Cardiomyopathy; Chagas Disease; Chromones; Dose-Response Relationship, Immunologic; Humans; In Vitro Techniques; Indomethacin; Leukocyte Count; Lymphocytes; Male; Masoprocol; Myocardial Contraction; Rats; Rats, Inbred Strains; SRS-A; Time Factors | 1984 |
Prostaglandins and related compounds -- a general physiologic control system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Diet; Epoprostenol; Fatty Acids; Female; Humans; Indomethacin; Pregnancy; Prostaglandins; SRS-A; Thromboxane A2; Thromboxanes | 1983 |
Lymphocytes sensitize rat isolated atria to the inotropic and chronotropic effects of sodium arachidonate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Heart Rate; In Vitro Techniques; Indomethacin; Lymphocytes; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Antiproliferative action of interferon on murine L1210 cells: interrelationship with prostaglandins.
Topics: Animals; Aspirin; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Growth Inhibitors; Indomethacin; Interferon Type I; Leukemia L1210; Mice; Prostaglandins | 1983 |
Activation of cyclic AMP-dependent protein kinase in macrophages.
Topics: Acetophenones; Animals; Aspirin; Calcimycin; Enzyme Activation; Indomethacin; Kinetics; Macrophages; Protein Kinases; Rats; Thioglycolates | 1984 |
Effects of the anti-inflammatory agents indomethacin, metiamide and acetylsalicylic acid on the induction of hyperplasia in hamster cheek-pouch epithelium and ear epidermis.
Topics: Animals; Aspirin; Cricetinae; Ear, External; Epidermis; Hyperplasia; Indomethacin; Mesocricetus; Metiamide; Mouth Mucosa; Podophyllin; Tetradecanoylphorbol Acetate; Thiourea; Turpentine | 1984 |
[Non-steroidal antiinflammatory agents--mechanisms of action].
Topics: Arachidonic Acids; Arthritis, Rheumatoid; Aspirin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Humans; Indomethacin; Lymphocytes; Prostaglandin Antagonists; Prostaglandins; Sodium Salicylate; Synovial Membrane | 1983 |
Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Enzyme Activation; Epinephrine; Humans; Indomethacin; Kinetics; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Thrombin; Trifluoperazine; Type C Phospholipases | 1984 |
Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Catechols; In Vitro Techniques; Indomethacin; Leydig Cells; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Pregnenolone; Propionates; Pyrazoles; Rats; Testosterone | 1984 |
Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Diet; Fatty Acids, Essential; Hexamethonium Compounds; Indomethacin; Ketoprofen; Male; Muscle Contraction; Physostigmine; Piroxicam; Rats; Rats, Inbred Strains; Tetrodotoxin; Thiazines; Urinary Bladder | 1984 |
Use of ibuprofen in unusual circumstances.
Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersensitivity; Drug Interactions; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Kidney; Kinetics; Lithium; Liver; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Phenytoin; Platelet Aggregation; Prostaglandins E; Warfarin | 1984 |
Reversible inhibition of thromboxane A2 production by imidazole 2-hydroxybenzoate (ITF 182) in the arachidonic acid injected rat. A comparison with acetylsalicylic acid and indometacin.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Imidazoles; Indomethacin; Injections, Intravenous; Male; Prostaglandins; Rats; Rats, Inbred Strains; Salicylates; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Comparative study on the effects of acetylsalicylic acid, indomethacin and paracetamol on metabolites of arachidonic acid in plasma, serum and urine in man.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Humans; Indomethacin; Prostaglandins E; Thromboxane B2 | 1983 |
Nonsteroidal anti-inflammatory drugs stimulate 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes.
Topics: Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Humans; Ibuprofen; Indomethacin; Kinetics; Lipoxygenase; Neutrophils | 1984 |
Effect of acetylsalicylic acid and of indomethacin on diuresis in man: the role of cyclo-oxygenase inhibition.
Topics: Adult; Aspirin; Chlorides; Cyclooxygenase Inhibitors; Depression, Chemical; Dinoprostone; Diuresis; Humans; Indomethacin; Male; Potassium; Prostaglandins E; Sodium | 1984 |
Effect of inhibitors of the lipoxygenase pathway on mouse myoblast fusion.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Fusion; Cells, Cultured; Cyclooxygenase Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Mice; Muscles; Pyrazoles; Umbelliferones | 1984 |
Role of eicosanoids in the control of renal function in severe hepatic disease.
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Humans; Ibuprofen; Indomethacin; Kidney; Lipoxygenase; Liver Cirrhosis; Phospholipases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Thromboxanes; Vasoconstriction | 1984 |
Therapeutic reduction of ongoing carrageenin-induced inflammation by lipoxygenase, but not cyclooxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Indomethacin; Inflammation; Lipoxygenase; Male; Pyrazoles; Rats; Time Factors | 1984 |
Hypersensitivity to norepinephrine in vasa deferentia from diabetic rats. Possible participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Catechols; Diabetes Mellitus, Experimental; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Prostaglandin D2; Prostaglandins; Prostaglandins D; Rats; Rats, Inbred Strains; Vas Deferens | 1984 |
Variable inotropic effect of immune cells on mice atria--participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Dithizone; In Vitro Techniques; Indomethacin; Lymph Nodes; Male; Masoprocol; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocardium; T-Lymphocytes | 1984 |
The combined effects of sodium salicylate, aspirin and indomethacin on the metabolism of arachidonic acid in human platelets.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Drug Interactions; Humans; In Vitro Techniques; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate | 1984 |
Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Complement C5; Complement C5a, des-Arginine; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Indomethacin; Lung; Muscle Contraction; Piroxicam; Prostaglandins E; Prostaglandins F; SRS-A; Thiazines; Thromboxane B2 | 1984 |
Comparative effects of some non-steroidal anti-inflammatory drugs on the ultrastructural integrity and prostaglandin levels in the rat gastric mucosa: relationship to drug uptake.
Topics: Animals; Anti-Inflammatory Agents; Apazone; Aspirin; Chromatography, Gas; Dinoprostone; Gastric Mucosa; Indomethacin; Intestinal Absorption; Kinetics; Lipoxygenase; Male; Mass Spectrometry; Microscopy, Electron; Propionates; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2 | 1984 |
Characteristics and effect of antiinflammatory drugs on adriamycin-induced inflammation in the mouse paw.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Diphenhydramine; Doxorubicin; Fenclonine; Hydrocortisone; Ibuprofen; Indomethacin; Inflammation; Male; Metiamide; Mice; Time Factors | 1980 |
N-(4-hydroxyphenyl)retinamide: a synthetic analog of vitamin A that is a potent inhibitor of prostaglandin biosynthesis.
Topics: Animals; Aspirin; Cells, Cultured; Dogs; Epoprostenol; Fenretinide; Fibroblasts; Humans; Indomethacin; Kidney; Mice; Muscle, Smooth; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Tretinoin | 1980 |
Thymus-dependent lymphocytes of dengue virus-infected mice spleens mediate suppression through prostaglandin.
Topics: Animals; Antibody Formation; Aspirin; B-Lymphocytes; Dengue; Hemolytic Plaque Technique; Indomethacin; Mice; Mice, Inbred Strains; Prostaglandin Antagonists; Prostaglandins; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory | 1981 |
Inhibition of murine tumor growth and prostaglandin synthesis by indomethacin.
Topics: Animals; Aspirin; Female; Humans; Immunosuppressive Agents; Indomethacin; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Prostaglandins; T-Lymphocytes, Regulatory; Transplantation, Homologous | 1980 |
Gamma-aminobutyric acid-induced contraction of the dog basilar artery.
Topics: Animals; Arachidonic Acids; Aspirin; Basilar Artery; Bicuculline; Dogs; Drug Interactions; Ethanol; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Indomethacin; Leukotrienes; Lipid Peroxides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Picrotoxin | 1984 |
Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atrophy; Cartilage, Articular; Dogs; Extracellular Matrix; Glycosaminoglycans; Indomethacin; Osteoarthritis; Prostaglandin Antagonists; Proteoglycans; Salicylates; Sulfur Radioisotopes; Sulindac; Uronic Acids | 1984 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin | 1984 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Effects of acetylcholine in the pulmonary circulation of rabbits.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Blood Pressure; Indomethacin; Male; Prostaglandins; Pulmonary Circulation; Rabbits; Vasoconstriction | 1984 |
[Formalin-induced minor tremor response as an indicator of pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Formaldehyde; Guinea Pigs; Hydrocortisone; Indomethacin; Levallorphan; Male; Morphine; Pain; Pyridinolcarbamate; Tremor | 1984 |
Blockade by anti-glucocorticoids, actinomycin D and cycloheximide of the anti-inflammatory action of some Kampohozai (Chinese traditional medicines) against serotonin.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cycloheximide; Dactinomycin; Dexamethasone; Drugs, Chinese Herbal; Glucocorticoids; Indomethacin; Inflammation; Magnoliopsida; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Methyltestosterone; Mice; Phenylbutazone; Phytotherapy; Progesterone; Serotonin; Serotonin Antagonists; Time Factors | 1984 |
Gastrointestinal ulcerogenic activity of tolmetin sodium in rats in comparison with those of indomethacin and aspirin.
Topics: Animals; Aspirin; Indomethacin; Male; Peptic Ulcer; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1984 |
Prostaglandin synthesis inhibitors in erythropoiesis.
Topics: Animals; Aspirin; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Erythropoiesis; Erythropoietin; Female; Hypoxia; Indomethacin; Mice; Mice, Inbred CBA; Polycythemia; Prostaglandin Antagonists; Spleen | 1984 |
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mellitus; Female; Humans; Indomethacin; Male; Myocardial Infarction; Physical Exertion; Pregnancy; Reference Values; Thromboxane B2; Thromboxanes | 1984 |
Effects of exogenous administration of female sex hormones on gastric secretion and ulcer formation in the rat.
Topics: Animals; Aspirin; Estrogens; Gastric Juice; Gonadal Steroid Hormones; Humans; Indomethacin; Male; Progesterone; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological | 1984 |
Development of a GC-MS method for quantitation of 2,3-dinor-6-keto-PGF1 alpha and determination of the urinary excretion rates in healthy humans under normal conditions and following drugs.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents; Aspirin; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Male; Middle Aged; Physical Exertion | 1984 |
Gastric cytoprotective properties of SCH 32651, a novel antiulcer agent.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cysteamine; Drug Evaluation, Preclinical; Duodenal Ulcer; Ethanol; Gastric Mucosa; Imidazoles; Indomethacin; Male; Pyrazines; Rats; Reserpine; Stomach Ulcer; Stress, Physiological | 1984 |
Demonstration of a pH gradient at the luminal surface of rat duodenum in vivo and its dependence on mucosal alkaline secretion.
Topics: Acetazolamide; Alkalies; Animals; Aspirin; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Female; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Male; Prostaglandins E; Prostaglandins E, Synthetic; Prostaglandins F; Rats | 1983 |
Non-steroidal anti-inflammatory drugs in the reduction of human alveolar bone loss.
Topics: Adult; Aged; Alveolar Process; Aspirin; Bone Resorption; Humans; Indomethacin; Male; Middle Aged; Retrospective Studies | 1983 |
Effects of non-steroidal anti-inflammatory drugs and prostaglandins on alkali secretion by rabbit gastric fundus in vitro.
Topics: Alkalies; Animals; Anti-Inflammatory Agents; Aspirin; Dinoprost; Dinoprostone; Gastric Fundus; In Vitro Techniques; Indomethacin; Mucous Membrane; Prostaglandins E; Prostaglandins F; Rabbits; Serous Membrane | 1983 |
Reduction of enzyme release from reperfused ischemic hearts by steroidal and non-steroidal prostaglandin synthesis inhibitors.
Topics: Animals; Aspirin; Coronary Disease; Creatine Kinase; Dexamethasone; Heart; Hydrocortisone; Indomethacin; L-Lactate Dehydrogenase; Male; Methylprednisolone; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1983 |
Effects of indomethacin, aspirin and related compounds on the transgastric potential difference in cats.
Topics: Animals; Aspirin; Cats; Dinoprostone; Female; Gastric Mucosa; Indomethacin; Infusions, Parenteral; Intubation, Gastrointestinal; Male; Membrane Potentials; Prostaglandins E; Salicylates; Salicylic Acid; Time Factors | 1983 |
Cytostatic and cytolytic activities of macrophages regulation by prostaglandins.
Topics: Animals; Aspirin; Cell Survival; Dexamethasone; Dinoprostone; DNA Replication; Indomethacin; Lymphocytes; Lymphokines; Macrophage Activation; Macrophages; Male; Mice; Prostaglandins; Prostaglandins E; Structure-Activity Relationship | 1984 |
Effects of salicylate and indomethacin on glycosaminoglycan and prostaglandin E2 synthesis in intact canine knee cartilage ex vivo.
Topics: Animals; Aspirin; Cartilage, Articular; Dinoprostone; Dogs; Glycosaminoglycans; Indomethacin; Prostaglandins E; Salicylates; Uronic Acids | 1984 |
Prostaglandins in peptic ulcer disease: effect of nonsteroidal anti-inflammatory compounds (NOSAC).
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Carbazoles; Duodenal Ulcer; Gastric Mucosa; Humans; Indomethacin; Prostaglandin Antagonists; Prostaglandins; Radioimmunoassay; Stomach Ulcer; Thromboxanes | 1984 |
Alkali secretion by isolated rabbit gastric mucosa: effects of non-steroidal anti-inflammatory drugs and prostaglandins.
Topics: Alkalies; Animals; Anti-Inflammatory Agents; Aspirin; Dinoprost; Dinoprostone; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits | 1984 |
Comparative therapeutic benefit of indomethacin, hydrochlorothiazide, and acetyl-salicylic acid in a patient with nephrogenic diabetes insipidus.
Topics: Adolescent; Aspirin; Diabetes Insipidus; Diabetic Nephropathies; Dinoprost; Dinoprostone; Diuresis; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Indomethacin; Male; Osmolar Concentration; Prostaglandins E; Prostaglandins F; Sodium; Thirst; Vasopressins | 1984 |
Prostaglandin synthesis in rat embryo tissue: the effect of non-steroidal anti-inflammatory drugs in vivo and ex vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Aspirin; Dinoprost; Embryo, Mammalian; Female; Indomethacin; Pregnancy; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Sex hormones and the motility of and prostaglandin output from, uterine horns of immature rats.
Topics: Animals; Aspirin; Estradiol; Female; Indomethacin; Progesterone; Prostaglandins E; Prostaglandins F; Rats; Sexual Maturation; Uterine Contraction; Uterus | 1984 |
Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth; Prostaglandins F; SRS-A; Thromboxane A2; Thromboxanes | 1984 |
Possible role of endogenous prostaglandins in alkaline response in rat gastric mucosa damaged by hypertonic NaCl.
Topics: Animals; Aspirin; Cimetidine; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Hydrogen-Ion Concentration; Hypertonic Solutions; Indomethacin; Male; Membrane Potentials; Prostaglandins; Prostaglandins E; Rats; Sodium Chloride | 1984 |
Possible role of prostaglandins in the regulation of food intake in the newborn rat.
Topics: Animals; Animals, Newborn; Animals, Suckling; Aspirin; Body Weight; Dinoprost; Dinoprostone; Eating; Female; Food Deprivation; Indomethacin; Injections, Intraperitoneal; Injections, Subcutaneous; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Time Factors | 1984 |
Functional cytoprotection by certain antacids.
Topics: Animals; Antacids; Aspirin; Dinoprostone; Ethanol; Gastric Acidity Determination; Gastric Mucosa; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1984 |
Effects of prostaglandin modifiers and zinc deficiency on possibly related functions in rats.
Topics: Alkaline Phosphatase; Animals; Aspirin; Body Weight; Immunity, Cellular; Indomethacin; Interleukin-2; Male; Organ Size; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Zinc | 1983 |
Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins.
Topics: Animals; Aspirin; Depression, Chemical; Dose-Response Relationship, Drug; Heart Atria; Indomethacin; Isoantibodies; Mice; Mice, Inbred BALB C; Myocardial Contraction; Pyrilamine; T-Lymphocytes; Time Factors | 1983 |
[Recently discovered mechanisms of action of non-steroidal antirheumatic agents: possible, not only symptomatic therapeutic effects].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Granulocytes; Humans; Immunoglobulin M; Indomethacin; Interleukin-2; Leukocytes; Prostaglandins; Rheumatoid Factor | 1983 |
[The analgesic and antipyretic effects of a non-steroidal anti-inflammatory drug, oxaprozin, in experimental animals].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Dogs; Ibuprofen; Indomethacin; Male; Mice; Oxaprozin; Phenylbutazone; Propionates; Rats | 1984 |
Effect on the human complement system of the major non-steroidal anti-inflammatory drugs: aspirin, indomethacin, phenylbutazone, oxyphenbutazone and sulindac.
Topics: Anti-Inflammatory Agents; Aspirin; Centrifugation, Density Gradient; Chromatography, Gel; Complement C3b Inactivator Proteins; Complement C5; Complement Inactivator Proteins; Complement Pathway, Classical; Dose-Response Relationship, Drug; Hemolysis; Humans; In Vitro Techniques; Indomethacin; Macromolecular Substances; Oxyphenbutazone; Phenylbutazone; Sulindac | 1983 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
[Response of isolated coronary artery segments to serotonin in the presence of a flavinoid, indomethacin and acetylsalicylate].
Topics: Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Scopoletin; Serotonin; Umbelliferones | 1983 |
Comparison of the effect of nonsteroidal and steroidal antiinflammatory agents on prostaglandin production during ovulation in the rabbit.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Diclofenac; Female; Fenoprofen; Indomethacin; Ovulation; Prostaglandins; Rabbits | 1983 |
Microvascular injury during gastric mucosal damage by anti-inflammatory drugs in pigs and rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Gastric Mucosa; Indomethacin; Microcirculation; Propionates; Rats; Swine | 1983 |
[Imadyl: gastric irritation in comparison with acetylsalicylic acid, indomethacin, piroxicam and diclofenac-Na].
Topics: Anti-Inflammatory Agents; Aspirin; Carbazoles; Diclofenac; Humans; Indomethacin; Male; Membrane Potentials; Piroxicam; Stomach; Thiazines | 1983 |
[Juvenile rheumatoid arthritis with adult onset. Report of 5 cases].
Topics: Adult; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Male; Methylprednisolone; Middle Aged | 1983 |
Disseminated intravascular coagulation complicating systemic juvenile chronic arthritis ("Still's disease").
Topics: Arthritis, Juvenile; Aspirin; Child; Disseminated Intravascular Coagulation; Female; Haemophilus Infections; Humans; Indomethacin; Male | 1983 |
Effect of salicylates on lymphocyte blastogenesis in vitro: association with other non-steroid anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Diflunisal; Humans; In Vitro Techniques; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Prostaglandin Antagonists; Salicylates; Sodium Salicylate | 1983 |
Effects of oxametacin on coumarin anticoagulation and on platelet function in humans.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Platelets; Drug Interactions; Female; Humans; Indomethacin; Male; Middle Aged; Platelet Aggregation; Serotonin; Time Factors; Warfarin | 1983 |
Effect of prostaglandin synthesis inhibitors on neurotensin and sodium salicylate-induced gastric cytoprotection in rats.
Topics: Animals; Aspirin; Cold Temperature; Ethanol; Humans; Indomethacin; Male; Neurotensin; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Restraint, Physical; Sodium Salicylate; Stomach Ulcer; Stress, Psychological | 1983 |
Anti-ulcer activity and other pharmacological properties of lozilurea.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Dogs; Duodenal Ulcer; Female; Gastric Mucosa; Guinea Pigs; Hexosamines; In Vitro Techniques; Indomethacin; Male; Mice; Mucoproteins; Proteins; Psychotropic Drugs; Rats; Rats, Inbred Strains; Stomach Ulcer; Urea | 1983 |
The origin of chemiluminescence produced by neutrophils stimulated by opsonized zymosan.
Topics: Arachidonic Acids; Aspirin; Catechols; Glucose; Humans; Indomethacin; Luminescent Measurements; Masoprocol; Neutrophils; Opsonin Proteins; Prostaglandins; Sodium Fluoride; Xanthine Oxidase; Zymosan | 1983 |
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia, General; Animals; Aspirin; Hypotension; Indomethacin; Lung; Male; Perfusion; Pressure; Pulmonary Artery; Pulmonary Embolism; Rabbits; Thromboxane B2; Thromboxanes | 1983 |
Effects of an antiulcer drug, sucralfate (a basic aluminum salt of sulfated disaccharide), on experimental gastric lesions and gastric secretion in rats.
Topics: Acetates; Aluminum; Animals; Anti-Ulcer Agents; Aspirin; Gastric Mucosa; Histamine; Indomethacin; Rats; Stomach Ulcer; Sucralfate | 1983 |
The incidence and natural history of pericardial effusion after cardiac surgery--an echocardiographic study.
Topics: Adult; Aged; Aspirin; Cardiac Surgical Procedures; Echocardiography; Female; Humans; Indomethacin; Male; Middle Aged; Pericardial Effusion; Postoperative Care; Postoperative Complications; Prednisone | 1984 |
Altered glomerular eicosanoid biosynthesis in uranyl nitrate-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Aspirin; Female; Indomethacin; Kidney Glomerulus; Kinetics; Prostaglandins; Radioimmunoassay; Rats; Rats, Inbred Strains; Uranium; Uranyl Nitrate | 1984 |
The effect of aspirin, indomethacin and sodium meclofenamate on coronary artery ligation arrhythmias in anaesthetized rats.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Aspirin; Coronary Vessels; Disease Models, Animal; Hemodynamics; Indomethacin; Ligation; Male; Meclofenamic Acid; Rats; Rats, Inbred Strains | 1984 |
Aspirin tolerance induced in aspirin-sensitive asthmatics.
Topics: Aspirin; Asthma; Cross Reactions; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Tolerance; Female; Humans; Immunization; Indomethacin; Male; Time Factors | 1984 |
Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats.
Topics: Animals; Aspirin; Benzimidazoles; Chemical Phenomena; Chemistry; Duodenal Ulcer; Epirizole; Gastric Juice; Indomethacin; Male; Omeprazole; Prednisolone; Rats; Rats, Inbred Strains; Stomach Ulcer | 1984 |
[Experimental models for peptic ulcer].
Topics: Animals; Aspirin; Disease Models, Animal; Dogs; Histamine; Immersion; Indomethacin; Peptic Ulcer; Rats; Stress, Physiological | 1984 |
Aspirin desensitization in aspirin-sensitive asthma: failure to maintain a desensitized state during prolonged therapy.
Topics: Adult; Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Female; Humans; Indomethacin; Male | 1984 |
Involvement of endogenous prostaglandin I2 in the vascular action of histamine in dogs.
Topics: Animals; Aspirin; Blood Vessels; Chlorpheniramine; Cimetidine; Dogs; Epoprostenol; Female; Histamine; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Tranylcypromine; Vasoconstriction; Vasodilation | 1982 |
Bleeding time in rats: a comparison of different experimental conditions.
Topics: Anesthetics; Animals; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelet Disorders; Dipyridamole; Disease Models, Animal; Epoprostenol; Heparin; Indomethacin; Rats; Tail; Thromboxane B2 | 1982 |
[Action of some salicylates associated with other non-steroidal anti-inflammatory drugs on the release of prostacyclin from the gastric mucosa of the rat].
Topics: Animals; Aspirin; Biological Assay; Diflunisal; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Rats; Salicylates; Sodium Salicylate | 1982 |
Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Indomethacin; Kinetics; Lipoxygenase; Male; Neutrophils; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship | 1980 |
Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Peroxidases; Salicylates | 1980 |
Cerebral vasospasm: effects of prostaglandin synthetase inhibitors in vitro.
Topics: Animals; Arachidonic Acids; Aspirin; Basilar Artery; Cyclooxygenase Inhibitors; Dogs; Female; In Vitro Techniques; Indomethacin; Ischemic Attack, Transient; Male; Meclofenamic Acid; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandins F; Serotonin; Vasoconstriction | 1980 |
The influence of haemoglobin on the inhibition of prostaglandin synthase by anti-inflammatory drugs [proceedings].
Topics: Animals; Aspirin; Cattle; Cyclooxygenase Inhibitors; Glutathione; Hemoglobins; Indomethacin; Kinetics; Male; Oxidation-Reduction; Seminal Vesicles | 1980 |
Effects of prostaglandin inhibitors on pituitary and thyroid responses to thyrotropin-releasing hormone in man: PGs and pituitary-thyroid system.
Topics: Adult; Aged; Aspirin; Humans; Indomethacin; Male; Middle Aged; Pituitary Gland; Prolactin; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1980 |
Canine lymphosarcoma: a model for study of the hypercalcemia of cancer.
Topics: Animals; Antineoplastic Agents; Aspirin; Bone Resorption; Calcium; Disease Models, Animal; Dog Diseases; Dogs; Hypercalcemia; Indomethacin; Kidney; Lymphoma, Non-Hodgkin; Parathyroid Hormone; Prostaglandins E | 1980 |
Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Constriction, Pathologic; Guinea Pigs; Histamine; Hypersensitivity; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Prostaglandins E, Synthetic; SRS-A; Tracheal Diseases | 1980 |
Involvement of bivalent cations and arachidonic acid in neutrophil aggregation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Cell Aggregation; Humans; Indomethacin; Magnesium; Neutrophils | 1980 |
[Prevention of food hypersensitivities with aspirin].
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Food Hypersensitivity; Ibuprofen; Indomethacin; Milk; Prostaglandin Antagonists; Shellfish | 1980 |
The action of cyclooxygenase and prostacyclin-synthetase inhibitors on platelet-vessel wall interaction.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Flurbiprofen; Indomethacin; Intramolecular Oxidoreductases; Male; Mesenteric Arteries; Perfusion; Prostaglandins; Rats | 1980 |
[Lipoperoxides and cyclooxygenase activity in thrombocytes in relation to the age of healthy subjects and drugs affecting prostaglandin biosynthesis (Acylpyrin, Indren, Erevit forte)].
Topics: Adult; Age Factors; Aged; Aspirin; Blood Platelets; Female; Humans; Indomethacin; Lipid Peroxides; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Vitamin E | 1980 |
[Evaluation of the effect of ibuprofen lysinate on lymphocytic transformation in vitro. Comparison with meglumine indomethacinate, phenylbutazone, and lysine acetylsalicylate].
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lysine; Meglumine; Phenylbutazone | 1980 |
Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Indomethacin; Intestinal Diseases; Male; Prostaglandins; Rats; Stomach Ulcer; Time Factors; Ulcer | 1981 |
Initiation of human parturition. XII. Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua.
Topics: Amnion; Aspirin; Cesarean Section; Chorion; Cyclooxygenase Inhibitors; Decidua; Extraembryonic Membranes; Female; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Labor Onset; Labor, Obstetric; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1981 |
[Inhibitory action of non-steroidal anti-flammatory drugs on prostaglandin synthesis and release (author's transl)].
Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; Diclofenac; Flurbiprofen; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Synovial Membrane; Synovitis; Thiazoles | 1980 |
Prostaglandin synthetase inhibitors in the treatment of nephrogenic diabetes insipidus.
Topics: Aspirin; Body Water; Child; Cyclooxygenase Inhibitors; Diabetes Insipidus; Humans; Hydrochlorothiazide; Hypernatremia; Indomethacin; Infant; Kidney; Male; Polyuria | 1981 |
Activation of macrophages for tumor cell cytotoxicity: identification of indomethacin sensitive and insensitive pathways.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Aspirin; Cattle; Cell Adhesion; Cytotoxicity, Immunologic; Indomethacin; Lipopolysaccharides; Lymphokines; Lymphoma, Non-Hodgkin; Macrophages; Mast-Cell Sarcoma; Mice; Mice, Inbred C3H; Prostaglandins E | 1981 |
Interaction of rat platelets with Listeria monocytogenes.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Female; Indomethacin; Listeria monocytogenes; Listeriosis; Platelet Aggregation; Rats; Serotonin | 1981 |
Platelet adherence to collagen: role of prostaglandin-thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Imidazoles; Indomethacin; Magnesium; Middle Aged; Platelet Adhesiveness; Prostaglandins; Serotonin; Temperature; Thromboxanes | 1981 |
Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Digestive System; Flurbiprofen; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Ketoprofen; Naproxen; Prostaglandins; Rats | 1981 |
Testosterone potentiation of ionophore and ADP induced platelet aggregation: relationship to arachidonic acid metabolism.
Topics: Adenosine Diphosphate; Animals; Anti-Bacterial Agents; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Humans; Indomethacin; Platelet Aggregation; Rabbits; Serum Albumin; Testosterone; Thromboxane A2 | 1981 |
A study of intravascular platelet aggregation by continuous platelet counting.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Imidazoles; Indomethacin; Male; Platelet Aggregation; Platelet Count; Prostaglandins H; Rabbits; Rats; Time Factors | 1981 |
Effect of non-steroidal anti-inflammatory drugs on arachidonic acid metabolism.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Leukotrienes; Lipid Peroxides; Lipoxygenase; Peroxidases; Prostaglandin-Endoperoxide Synthases | 1981 |
Arachidonic acid, prostaglandin E2 and F2 alpha influence rates of protein turnover in skeletal and cardiac muscle.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cycloheximide; Diaphragm; Dinoprost; Dinoprostone; Indomethacin; Kinetics; Meclofenamic Acid; Muscle, Smooth; Muscles; Myocardium; Organ Specificity; Prostaglandins E; Prostaglandins F; Proteins; Rats | 1982 |
Delay in hamster buccal pouch carcinogenesis by aspirin and indomethacin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Aspirin; Carcinoma, Squamous Cell; Cheek; Cricetinae; Female; Indomethacin; Male; Mesocricetus; Mouth Neoplasms; Neoplasms, Experimental; Time Factors | 1982 |
Appearance of thrombocytopenia and benign monoclonal gammopathy following intake of drugs.
Topics: Aged; Ampicillin; Aspirin; Dipyrone; Female; Humans; Hypergammaglobulinemia; Indomethacin; Male; Middle Aged; Thrombocytopenia | 1982 |
A proposed role for prostaglandins in the modulation of the relaxation response to urotensin I in isolated rat arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Atropine; Dose-Response Relationship, Drug; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Peptides; Propranolol; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains; Urotensins | 1981 |
Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Edema; Hyperalgesia; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Rats | 1981 |
Variables associated with radioimmunoassay of prostaglandins in plasma.
Topics: Aspirin; Edetic Acid; False Positive Reactions; Humans; Indomethacin; Prostaglandins; Radioimmunoassay; Specimen Handling; Thromboxane B2 | 1981 |
The effect of aspirin on prostaglandin synthetase.
Topics: Acetylation; Aspirin; Blood Platelets; Blood Proteins; Fatty Acids, Unsaturated; Humans; Indomethacin; Kinetics; Prostaglandin-Endoperoxide Synthases | 1981 |
Five methoxy-2-methyl-3-indole acetic acid. A metabolite and alkali hydrolysis product of indomethacin, markedly inhibits platelet aggregation only in the presence of aorta or a product released by aorta.
Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Epoprostenol; Indoleacetic Acids; Indomethacin; Male; Mice; Platelet Aggregation; Tissue Extracts | 1982 |
The effect of some antirheumatic drugs in vivo on the response of spleen cells to concanavalin A in rats with chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Chronic Disease; Concanavalin A; Female; Gold Sodium Thiomalate; Indomethacin; Inflammation; Levamisole; Penicillamine; Rats; Rats, Inbred Strains; Spleen | 1982 |
The stimulation of protein degradation in muscle by Ca2+ is mediated by prostaglandin E2 and does not require the calcium-activated protease.
Topics: Animals; Aspirin; Calcimycin; Calcium; Dinoprost; Dinoprostone; Endopeptidases; Ethers; Indomethacin; Ionomycin; Muscle Proteins; Muscles; Potassium; Prostaglandins E; Prostaglandins F; Rats | 1982 |
Studies on the incorporation of [1-14C]arachidonic acid into glycerolipids and its conversion into prostaglandins by rabbit iris. Effects of anti-inflammatory drugs and phospholipase A2 inhibitors.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Diglycerides; Female; Indomethacin; Iris; Lipid Metabolism; Male; Microsomes; Muscle, Smooth; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandins; Quinacrine; Rabbits; Triglycerides | 1982 |
[Effect of prostaglandin-synthetase inhibitors on responses of segments of coronary arteries to 4-methylesculetol and/or to angiotensin II].
Topics: Angiotensin II; Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Lysine; Muscle, Smooth, Vascular; Scopoletin; Umbelliferones | 1981 |
Salicylic acid blocks indomethacin- and aspirin-induced cyclo-oxygenase inhibition in rat gastric mucosa.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Drug Interactions; Gastric Mucosa; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandins F; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1982 |
Effects of non-steroidal anti-inflammatory drugs on fatty acid cyclooxygenase and prostaglandin hydroperoxidase activities.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Dose-Response Relationship, Drug; Indomethacin; Microsomes; Peroxidases; Prostaglandin-Endoperoxide Synthases; Time Factors | 1982 |
Indomethacin prevents the long-lasting inhibitory effect of aspirin on human platelet cyclo-oxygenase activity.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Indomethacin; Male; Platelet Aggregation; Time Factors | 1982 |
Effect of administering two prostaglandin synthetase inhibitors (indomethacin and aspirin) on egg production in the domestic fowl (Gallus domesticus).
Topics: Administration, Oral; Animals; Aspirin; Chickens; Female; Indomethacin; Injections, Intramuscular; Oviducts; Oviposition; Prostaglandin-Endoperoxide Synthases | 1982 |
Effects of prostaglandin synthetase inhibitors, salt overload and renomedullary dissection on the hypoxia stimulated erythropoietin production in rats.
Topics: Acute Disease; Animals; Aspirin; Cyclooxygenase Inhibitors; Dissection; Erythropoietin; Hypoxia; Indomethacin; Kidney Medulla; Male; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Sodium Chloride | 1980 |
The role of prostaglandins in the lower urinary tract dynamics of prostatectomized patients: a trial with indomethacin and aspirin.
Topics: Aspirin; Humans; Indomethacin; Male; Prostaglandins; Prostatectomy; Urinary Tract; Urodynamics | 1983 |
Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Carrageenan; Clonidine; Drug Therapy, Combination; Edema; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1983 |
Effects of 16,16-dimethyl-PGE2-methyl ester on aspirin- and indomethacin-induced gastric and intestinal lesions in mini pigs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Female; Gastrointestinal Diseases; Indomethacin; Intestines; Male; Prostaglandins E, Synthetic; Stomach; Swine; Swine, Miniature | 1983 |
C5a and antigen-induced tracheal contraction: effect of a combination of an antihistamine and cyclo-oxygenase inhibitors.
Topics: Animals; Antigens; Aspirin; Complement C5; Complement C5a; Diphenhydramine; Drug Synergism; Ethanol; Guinea Pigs; Histamine; Indomethacin; Muscle Contraction; Muscle, Smooth; Oxygenases; Tachyphylaxis; Trachea | 1983 |
Protection from arrhythmias of cultured heart cells by nonsteroidal antiinflammatory drugs.
Topics: Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Aspirin; Cells, Cultured; Indomethacin; Rats; Salicylates; Salicylic Acid; Sulfinpyrazone; Time Factors | 1983 |
Pleuropericarditis: an extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature.
Topics: Adult; Aspirin; Colitis, Ulcerative; Crohn Disease; Humans; Indomethacin; Male; Middle Aged; Pericarditis; Pleural Effusion; Prednisone | 1983 |
Effect of inhibitors of prostaglandin synthesis on hepatic drug clearance.
Topics: Adult; Antipyrine; Aspirin; Humans; Indocyanine Green; Indomethacin; Liver; Male; Prostaglandin Antagonists | 1983 |
Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration.
Topics: Adult; Aged; Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Indomethacin; Male; Middle Aged; Rhinitis, Allergic, Perennial; Sinusitis; Skin Tests | 1983 |
Gastric antisecretory and cytoprotective activities of SCH 28080.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine; Imidazoles; Indomethacin; Male; Membrane Potentials; Rats; Stomach Ulcer; Stress, Physiological | 1983 |
Steroid economising effects of a calf thymus extract in three patients with juvenile chronic arthritis.
Topics: Animals; Arthritis, Juvenile; Aspirin; Azathioprine; Cattle; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Prednisone; Thymus Extracts | 1983 |
Effects of aspirin and indomethacin on cerebral circulation in the conscious rat: evidence for a physiological role of endogenous prostaglandins.
Topics: Animals; Aspirin; Brain; Cerebrovascular Circulation; Consciousness; Indomethacin; Kinetics; Male; Prostaglandins; Rats; Rats, Inbred Strains; Vascular Resistance | 1983 |
[Effects of SM powder, a combined herbal preparation for stomach diseases, on gastric secretion and acute gastro-duodenal lesions in rats].
Topics: Animals; Aspirin; Depression, Chemical; Duodenal Ulcer; Ethanol; Gastric Juice; Immersion; Indomethacin; Male; Plants, Medicinal; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological | 1983 |
Exacerbation of acetic acid ulcer induced by non-steroidal anti-inflammatory drugs in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Aspirin; Gastric Emptying; Gastric Juice; Gastric Mucosa; Hexosamines; Indomethacin; Male; Phenylbutazone; Rats; Stomach Ulcer | 1983 |
Vasodilatory effects of vasoactive intestinal polypeptide (VIP) on isolated rat arteries.
Topics: Animals; Aorta, Thoracic; Arteries; Aspirin; Female; Gastrointestinal Hormones; In Vitro Techniques; Indomethacin; Mesenteric Arteries; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide; Vasodilator Agents | 1983 |
Release of chondrocyte-stimulating factor by rabbit peritoneal macrophages.
Topics: Animals; Aspirin; Cartilage, Articular; Indomethacin; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mice; Paramethasone; Peritoneum; Prostaglandins E; Proteins; Rabbits | 1981 |
The influence of acetylsalicylic acid, phenylbutazone, indomethacin, and flufenamic acid on the kinetics of leucocytes during acute inflammation.
Topics: Analgesics; Animals; Aspirin; Cell Movement; Flufenamic Acid; Indomethacin; Inflammation; Kinetics; Leukocytes; Male; Phenylbutazone; Rats | 1980 |
Clinical effects of indomethacin and additive clinical effect of indomethacin during salicylate maintenance therapy.
Topics: Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Protein Binding | 1981 |
Allergen tachyphylaxis of guinea pigs in vivo; a prostaglandin E mediated phenomenon?
Topics: Aerosols; Animals; Aspirin; Bronchial Provocation Tests; Dinoprostone; Guinea Pigs; Indomethacin; Male; Ovalbumin; Prostaglandins E; Tachyphylaxis | 1981 |
Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Cathartics; Cricetinae; Diarrhea; Dinoprostone; Erythrocyte Membrane; Flufenamic Acid; Hemolysis; Indomethacin; Intestinal Mucosa; Intestines; Male; Meclofenamic Acid; Mefenamic Acid; Mesocricetus; Prostaglandin Antagonists; Prostaglandins E | 1982 |
Role of prostaglandin E2 on gastric ulcers induced by non-steroidal anti-inflammatory compounds (NOSAC).
Topics: Animals; Aspirin; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1981 |
[The role of endogenous prostaglandin in drug-induced gastrointestinal lesions--comparison of aspirin and indomethacin (author's transl)].
Topics: Animals; Aspirin; Dinoprostone; Gastric Mucosa; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Male; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer; Ulcer | 1981 |
Role of prostaglandins in rat pineal neuroeffector junction. Changes in melatonin and norepinephrine release in vitro.
Topics: Alprostadil; Animals; Aspirin; Dinoprost; Dinoprostone; Indomethacin; Male; Mefenamic Acid; Melatonin; Norepinephrine; Pineal Gland; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1982 |
Treatment of Sjogren's syndrome with essential fatty acids, pyridoxine and vitamin C.
Topics: Ascorbic Acid; Aspartate Aminotransferases; Aspirin; Fatty Acids, Essential; Female; Humans; Indomethacin; Pyridoxine; Sjogren's Syndrome | 1982 |
[Effects produced in vitro and in vivo on the migration of rat polymorphonuclear leukocytes by anti-inflammatory drugs used in dentistry].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Migration Inhibition; Chemotaxis, Leukocyte; Dexamethasone; Indomethacin; Neutrophils; Niflumic Acid; Rats; Rats, Inbred Strains | 1982 |
The medical management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Humans; Indomethacin; Rest | 1982 |
Suppression of thyroid proliferative response to exogenous TSH by prostaglandin synthesis inhibitors.
Topics: Animals; Aspirin; Cell Division; Colchicine; Hydrocortisone; Indomethacin; Male; Mitotic Index; Prostaglandin Antagonists; Rats; Thyroid Gland; Thyrotropin | 1980 |
[Anti-inflammatory or antirheumatic? On the pharmalogical and therapeutic efficacy of non-steroidal antiinflammatory agents: a comparative study. II].
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Indomethacin; Phenylbutazone; Phenylpropionates; Prognosis; Rheumatic Diseases | 1980 |
[Experiences in the determination of serum indomethacin levels in patients with rheumatic diseases--a contribution to the "reliability" in clinico-pharmacological studies].
Topics: Aspirin; Drug Antagonism; Humans; Indomethacin; Patient Compliance; Rheumatic Diseases | 1980 |
[Effect of antirheumatic preparations on myocardial contractile function].
Topics: Adolescent; Adult; Aspirin; Dexamethasone; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Humans; Indomethacin; Male; Myocardial Contraction; Prednisolone; Rheumatic Diseases; Time Factors | 1981 |
Feedback suppression of the immune response in vivo. II. Involvement of prostaglandins in the generation of suppressor-inducer B lymphocytes.
Topics: Animals; Aspirin; B-Lymphocytes; Dose-Response Relationship, Immunologic; Feedback; Indomethacin; Lymphocyte Cooperation; Male; Mice; Mice, Inbred C57BL; Prostaglandins; Spleen; T-Lymphocytes; Transplantation Immunology | 1982 |
Rheumatoid arthritis IV: non-steroidal anti-inflammatory agents use in treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Tolmetin | 1982 |
[Comparison of the effect of 3-amino-4-mercapto-6-methylpyridazine with various antiphlogistic agents in rat models of inflammation].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Disease Models, Animal; Edema; Evans Blue; Exudates and Transudates; Granuloma; Indomethacin; Inflammation; Kaolin; Male; Phenylbutazone; Pyridazines; Rats; Rats, Inbred Strains | 1982 |
Endogenous mechanisms that regulate prostacyclin release.
Topics: Angiotensin I; Angiotensin II; Animals; Aspirin; Biological Assay; Cats; Epoprostenol; Gas Chromatography-Mass Spectrometry; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Platelet Aggregation; Prostaglandins; Rabbits | 1980 |
Indomethacin and aspirin prevent the starvation-induced fall in plasma insulin.
Topics: Adult; Aspirin; Female; Glucagon; Humans; Indomethacin; Insulin; Kinetics; Male; Middle Aged; Obesity; Starvation | 1980 |
Prostacyclin reversal of aspirin and indomethacin effects on blood pressure responses to norepinephrine.
Topics: Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Epoprostenol; Heart Rate; Indomethacin; Male; Norepinephrine; Prostaglandins; Rats; Time Factors | 1980 |
Aspirin and indomethacin enhance platelet aggregation in mouse mesenteric arterioles.
Topics: Animals; Arteries; Arterioles; Aspirin; Capillaries; Epoprostenol; Indomethacin; Male; Mesentery; Mice; Mice, Inbred ICR; Platelet Aggregation; Stimulation, Chemical | 1980 |
The effect of prostaglandin synthesis inhibition of the acute blood pressure reduction by captopril in pentobarbital-anaesthetized rats.
Topics: Anesthesia; Animals; Aspirin; Blood Pressure; Captopril; Drug Interactions; Heart Rate; Indomethacin; Male; Pentobarbital; Proline; Prostaglandins; Rats; Time Factors | 1980 |
Prostacyclin effects on the blood pressure responses to norepinephrine in rats treated with aspirin or indomethacin.
Topics: Animals; Aspirin; Blood Pressure; Epoprostenol; Indomethacin; Male; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandins; Prostaglandins E; Rats | 1980 |
Role of arachidonic acid metabolites in the hypothalamic control of ovulation in the rat.
Topics: Acetaminophen; Animals; Arachidonic Acids; Aspirin; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Imidazoles; Indomethacin; Leukotrienes; Lipid Peroxides; Ovulation; Peroxides; Pregnancy; Proestrus; Rats | 1980 |
Bartter's syndrome: effect of indomethacin on prostaglandins, urinary kallikrein, renin-angiotensin-aldosterone system, and the response to angiotensin II antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Aminoglutethimide; Angiotensin II; Aspirin; Bartter Syndrome; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Indomethacin; Kallikreins; Male; Middle Aged; Prostaglandins E; Renin; Spironolactone | 1980 |
Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Crotalid Venoms; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lectins, C-Type; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1980 |
The role of Aspergillus fumigatus antigens in blood coagulation and platelet function.
Topics: Animals; Antigens, Fungal; Aspergillus fumigatus; Aspirin; Blood Coagulation; Indomethacin; Lidocaine; Platelet Aggregation; Rabbits | 1980 |
Humoral heartache -- do platelets have a role?
Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Aspirin; Blood Platelets; Coronary Circulation; Dogs; Epoprostenol; Humans; Indomethacin; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Respiratory movements alter the generation of prostacyclin and thromboxane A2 in isolated rat lungs: the influence of arachidonic acid-pathway inhibitors on the ratio between pulmonary prostacyclin and thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Epoprostenol; Fatty Acids; Hyperventilation; Indomethacin; Lung; Male; Prostaglandins; Prostaglandins F; Rats; Thromboxane A2; Thromboxanes; Tranylcypromine | 1981 |
Headache mechanisms.
Topics: Aspirin; Epoprostenol; Humans; Indomethacin; Prostaglandins; Prostaglandins E; Vascular Headaches | 1981 |
Prostacyclin (PGI2) and U-46619 stimulate coronary arteries from diabetic dogs and their action is influenced by inhibitors of prostaglandin biosynthesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agents; Aspirin; Coronary Vessels; Corticosterone; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Imidazoles; Indoles; Indomethacin; Kinetics; Pancreatectomy; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pyridines | 1981 |
Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration.
Topics: Animals; Aspirin; Capillary Permeability; Cell Movement; Chemotactic Factors; Escherichia coli; Hyperemia; Indomethacin; Inflammation; Mechlorethamine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Rabbits; Skin; Zymosan | 1981 |
The role of prostaglandins in the regulation of gastric mucosal blood flow.
Topics: Animals; Aspirin; Dinoprostone; Dogs; Epoprostenol; Gastric Mucosa; Indomethacin; Prostaglandins; Prostaglandins E; Rats; Regional Blood Flow | 1981 |
Prostaglandins in shock: to give or to block?
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Epoprostenol; Hemodynamics; Indomethacin; Papio; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Shock, Septic | 1980 |
Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dogs; Female; Hemodynamics; Imidazoles; Indomethacin; Male; Myocardial Contraction; Positive-Pressure Respiration; Prostaglandins; Thromboxane B2 | 1981 |
Effect of platelet-activating factor (PAF) on human platelets.
Topics: Animals; Antimycin A; Aspirin; Blood Platelets; Cattle; Creatine Kinase; Deoxyglucose; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin | 1982 |
The effect of nonsteroidal anti-inflammatory agents on E. coli-induced inflammation.
Topics: Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Dinoprostone; Escherichia coli Infections; Humans; In Vitro Techniques; Indomethacin; Inflammation; Neutrophils; Prostaglandins E; Regional Blood Flow; Time Factors | 1982 |
Hypoventilation and elevation of end-expiratory pressure release a substance which relaxes isolated arteries and disaggregates platelets in the presence of cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Biological Assay; Cats; Cattle; Dogs; Epoprostenol; Hypoventilation; Indomethacin; Lung Volume Measurements; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandins; Rabbits; Rats | 1981 |
Prevention of ethanol and aspirin-induced gastric mucosal lesions by paracetamol and salicylate in rats: role of endogenous prostaglandins.
Topics: Acetaminophen; Animals; Aspirin; Epoprostenol; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains; Sodium Salicylate; Stomach Ulcer | 1982 |
Effects of furosemide on prostacyclin-like antiaggregatory release from vessel wall and renal cortex.
Topics: Animals; Aorta; Aspirin; Blood Vessels; Epoprostenol; Female; Furosemide; In Vitro Techniques; Indomethacin; Kidney Cortex; Pentoxifylline; Platelet Aggregation; Prostaglandins; Rats; Rats, Inbred Strains | 1982 |
Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?
Topics: Animals; Aspirin; Constriction, Pathologic; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Disease Models, Animal; Dogs; Heparin; Ibuprofen; Indomethacin; Platelet Aggregation | 1982 |
Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Hypersensitivity; Forced Expiratory Volume; Humans; Indomethacin; Middle Aged; Time Factors | 1982 |
Ethanol potentiation of aspirin-induced prolongation of the bleeding time.
Topics: Adult; Alcoholic Beverages; Aspirin; Bleeding Time; Drug Synergism; Female; Hemostasis; Humans; Ibuprofen; Indomethacin; Male; Platelet Function Tests; Time Factors | 1982 |
Changes in serum and urinary zinc induced by ASA and Indomethacin.
Topics: Aspirin; Humans; Indomethacin; Zinc | 1982 |
Comparison of the effects of aspirin and indomethacin on aortic atherogenesis induced in rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Aspirin; Blood Coagulation; Cholesterol; Diet, Atherogenic; Indomethacin; Male; Platelet Aggregation; Rabbits; Triglycerides | 1982 |
Effects of aspirin, prednisolone and indomethacin on nephrotoxic serum nephritis in the rat.
Topics: Animals; Aspirin; Indomethacin; Kidney; Kidney Function Tests; Male; Nephritis; Prednisolone; Proteinuria; Rats; Rats, Inbred Strains | 1982 |
The influence of paracetamol on the erosive activity of indomethacin in the rat stomach.
Topics: Acetaminophen; Administration, Oral; Animals; Aspirin; Indomethacin; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Time Factors | 1982 |
The use of indomethacin in the treatment of pericarditis in childhood.
Topics: Adolescent; Aspirin; Child; Female; Humans; Indomethacin; Male; Pericarditis; Prednisone; Radiography; Recurrence | 1982 |
[Effect of inhibition of prostaglandin biosynthesis on the spike activity and chemical sensitivity of cortical neurons in the rabbit].
Topics: Acetylcholine; Action Potentials; Animals; Aspirin; Cerebral Cortex; Drug Interactions; Indomethacin; Male; Norepinephrine; Phenylbutazone; Prostaglandins; Rabbits | 1982 |
Effect of nonsteroidal anti-inflammatory agents on immune complex- and chemotactic factor-induced inflammation.
Topics: Animals; Antigen-Antibody Complex; Aspirin; Chemotactic Factors; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Indomethacin; Inflammation; Kinetics; Phagocytosis; Prostaglandins E; Rabbits | 1982 |
Basic and clinical studies of prodrugs of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biotransformation; Humans; Indomethacin; Phenylbutazone; Phenylbutyrates; Propionates; Rats | 1982 |
Ulcerogenic properties of anti-inflammatory drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Indomethacin; Peptic Ulcer | 1982 |
Aspirin-induced hypocalcemia in the rat.
Topics: Adrenalectomy; Animals; Aspirin; Body Weight; Calcium; Hypocalcemia; Indomethacin; Male; Nephrectomy; Parathyroid Glands; Rats; Rats, Inbred Strains; Thyroidectomy; Time Factors | 1982 |
Influence of anti-rheumatic drugs on the activity of collagenolytic cathepsin in hepatic culture.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Cathepsins; Culture Techniques; Indomethacin; L-Lactate Dehydrogenase; Liver; Naproxen; Phenylbutazone; Proteins; Rats; Rats, Inbred Strains | 1982 |
Effects of common analgesics on the in vitro suppression of lymphocyte mitogen responses by cephalosporins.
Topics: Acetaminophen; Analgesics; Aspirin; Cephalosporins; Drug Interactions; Humans; In Vitro Techniques; Indomethacin; Kinetics; Lymphocytes; Mitogens; Phytohemagglutinins | 1982 |
Testing for drugs inhibiting the formation of gastric ulcers.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Cold Temperature; Copper; Indomethacin; Mucus; Organometallic Compounds; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Salicylates; Stomach Ulcer; Stress, Physiological | 1982 |
Vasodilators and prostaglandin inhibitors in primary pulmonary hypertension.
Topics: Adolescent; Adult; Aspirin; Diazoxide; Dipyridamole; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Indomethacin; Isoproterenol; Isosorbide Dinitrate; Middle Aged; Phentolamine; Prostaglandin Antagonists; Tolazoline; Vascular Resistance; Vasodilator Agents | 1982 |
Biphasic modulation of platelet phospholipase A2 activity and platelet aggregation by mepacrine (quinacrine).
Topics: Animals; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Indomethacin; Male; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Aggregation; Quinacrine; Rats; Substrate Specificity | 1982 |
Effect of crude and purified human chorionic gonadotropin on murine delayed-type hypersensitivity: a role for prostaglandins.
Topics: Animals; Aspirin; Chorionic Gonadotropin; Female; Hypersensitivity, Delayed; Indomethacin; Male; Mice; Mice, Inbred Strains; Prostaglandins; Species Specificity | 1982 |
[Gastric tolerance of diphenpyramide after long-term treatment. Evaluation of the electric potential difference in the stomach].
Topics: Acetamides; Anti-Inflammatory Agents; Aspirin; Drug Tolerance; Humans; Indomethacin; Membrane Potentials; Stomach | 1982 |
Reduction of the erythema response to ultraviolet light by nonsteroidal antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Aspirin; Erythema; Humans; Ibuprofen; Indomethacin; Ultraviolet Rays | 1982 |
Inhibitors of immune complex induced human platelet aggregation and release in plasma.
Topics: Antibodies; Antigen-Antibody Complex; Aspirin; Blood Platelets; Depression, Chemical; Dipyridamole; DNA; Humans; Imidazoles; Indomethacin; Lupus Erythematosus, Systemic; Male; Platelet Aggregation; Quinazolines; Receptors, Fc; Sulfinpyrazone | 1982 |
The renal tubular defect of Bartter's syndrome.
Topics: Adult; Aspirin; Bartter Syndrome; Diet; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Indomethacin; Kidney Concentrating Ability; Kidney Tubules; Loop of Henle; Male; Potassium; Sodium | 1982 |
Platelet aggregation in laminar flow. II. Shear rate and ADP-dependent effects of acetylsalicylic acid and indomethacin.
Topics: Adenosine Diphosphate; Aspirin; Environment, Controlled; Humans; Indomethacin; Nephelometry and Turbidimetry; Platelet Adhesiveness; Platelet Aggregation; Time Factors | 1982 |
[Interactions of digoxin and the nonsteroidal anti-inflammatory drugs, acetylsalicylic acid and nifedipine].
Topics: Adult; Arthritis; Aspirin; Coronary Disease; Digoxin; Drug Interactions; Humans; Indomethacin; Male; Middle Aged; Neuritis; Nifedipine; Phenylbutazone; Pyridines | 1982 |
In vitro reduction of human blood kininogen by catecholamines.
Topics: Adolescent; Adult; Animals; Aspirin; Catecholamines; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Kininogens; Male; Middle Aged; Phenoxybenzamine; Propranolol | 1982 |
Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bivalvia; Female; Freeze Drying; Indomethacin; Male; Rats; Stomach Ulcer | 1980 |
Effects of CL-1700 and its constituents on acute or chronic gastric lesions and gastric secretion in rats.
Topics: Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dipeptides; Gastric Juice; Histamine; Humans; Indomethacin; Male; Rats; Stomach Ulcer; Stress, Psychological | 1982 |
Effect of non-steroid anti-inflammatory drugs in experimental myocardial infarction in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coronary Vessels; Indomethacin; Male; Myocardial Infarction; Rats; Salicylates; Sulfinpyrazone | 1981 |
Aspirin and indomethacin, nonsteroidal antiinflammatory agents alter the responses to microvascular injury in brain and mesentery.
Topics: Animals; Anti-Inflammatory Agents; Arterioles; Aspirin; Brain; Constriction, Pathologic; Dose-Response Relationship, Drug; Indomethacin; Male; Mesenteric Arteries; Mice; Mice, Inbred ICR; Microcirculation | 1980 |
Salicylate-arthropathy. Accelerated coxarthrosis during long-term treatment with acetylsalicylic acid.
Topics: Aged; Aspirin; Female; Hip; Humans; Indomethacin; Osteoarthritis | 1981 |
Psychosomatic stress and lipoperoxides of human platelet-rich plasma.
Topics: Aspirin; Female; Heart Failure; Humans; Indomethacin; Lipid Peroxides; Male; Middle Aged; Stress, Psychological; Vitamin E | 1980 |
Impaired red cell deformability in established adjuvant arthritic disease in rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Erythrocytes; Hemolysis; Hot Temperature; Hydrocortisone; In Vitro Techniques; Indomethacin; Male; Neuraminidase; Rats; Sialic Acids | 1980 |
Effect of indomethacin and aspirin on uterine activity in pregnant rats: comparison of circular and longitudinal muscle.
Topics: Animals; Aspirin; Endometrium; Female; Indomethacin; Myometrium; Organ Specificity; Pregnancy; Pregnancy, Animal; Prostaglandins F; Rats; Uterine Contraction; Uterus | 1981 |
Measurement of chemiluminescence in freshly drawn human blood. I. Role of granulocytes, platelets, and plasma factors in zymosan-induced chemiluminescence.
Topics: Aspirin; Blood Bactericidal Activity; Blood Platelets; Dose-Response Relationship, Drug; Granulocytes; Heparin; Humans; Indomethacin; Opsonin Proteins; Phagocytosis; Zymosan | 1981 |
[Aspirin and indomethacin therapy in 2 familial cases of Bartter's disease. Follow-up for growth and endocrine pattern].
Topics: Aspirin; Bartter Syndrome; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Growth; Humans; Hyperaldosteronism; Indomethacin | 1980 |
Prostaglandins /PGs/ and peristalsis.
Topics: Animals; Aspirin; Gastrointestinal Motility; Indomethacin; Intestine, Small; Male; Mice; Peristalsis; Prostaglandins; Suprofen | 1981 |
Articular manifestations of essential cryoglobulinemia.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Ankle; Arthritis; Arthrography; Aspirin; Blood Sedimentation; Child; Cryoglobulins; Female; Humans; Indomethacin; Male; Middle Aged; Tibia | 1981 |
Polymorphonuclear leukocyte response. Inhibition following corneal epithelial denudation by steroidal and nonsteroidal anti-inflammatory agents.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Cornea; Dexamethasone; Epithelium; Fluorometholone; Flurbiprofen; Indomethacin; Male; Neutrophils; Prednisolone; Rabbits | 1981 |
Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma.
Topics: Animals; Aspirin; Asthma; Atropine; Disease Models, Animal; Dogs; Female; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neuroeffector Junction; Tetrodotoxin; Trachea | 1981 |
Pharmacological studies of the involvement of hypothalamic prostaglandins in the regulation of thyrotropin secretion.
Topics: Animals; Aspirin; Electric Stimulation; Humans; Hypothalamus; Indomethacin; Kinetics; Prostaglandins; Rats; Thyroidectomy; Thyrotropin; Thyroxine | 1981 |
[Effect of various nonsteroid inflammatory agents on the behavior of rats].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Behavior, Animal; Indomethacin; Male; Motor Activity; Phenylbutazone; Rats | 1980 |
Pharmacology of human spontaneous monocyte-mediated cytotoxicity. I. Enhancement by salicylates and steroids.
Topics: Anti-Inflammatory Agents; Aspirin; Cytotoxicity, Immunologic; Humans; Hydrocortisone; Indomethacin; Killer Cells, Natural; Monocytes; Prostaglandins E; Salicylates | 1981 |
The role of endogenous prostaglandin E in angiotensin-II-induced drinking in rats.
Topics: Angiotensin II; Animals; Aspirin; Dose-Response Relationship, Drug; Drinking; Indomethacin; Male; Prostaglandins E; Rats; Satiety Response; Water-Electrolyte Balance | 1981 |
Indomethacin produces gastric antral ulcers in the refed rat.
Topics: Adrenalectomy; Animals; Aspirin; Fasting; Indomethacin; Intestines; Male; Phenylbutazone; Prostaglandins; Pyloric Antrum; Rats; Stomach Ulcer; Time Factors; Vagotomy | 1981 |
Local buccal mucosal effects of aspirin, indomethacin and isoxepac: their relationship to gastrointestinal damage.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Cheek; Dibenzoxepins; Gastrointestinal Diseases; Humans; Indomethacin; Mouth Mucosa; Time Factors | 1981 |
Effects of prostaglandin synthesis inhibitors on the anterior pituitary cell proliferation.
Topics: Animals; Aspirin; Indomethacin; Male; Mitosis; Pituitary Gland, Anterior; Rats | 1981 |
Interaction of indomethacin and aspirin or mepirizole in rats as shown by gastrointestinal ulcerogenic and anti-inflammatory activities.
Topics: Animals; Aspirin; Biological Transport; Charcoal; Drug Interactions; Edema; Epirizole; Indomethacin; Intestinal Diseases; Male; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Stomach Ulcer | 1980 |
[Increase of pulmonary vascular resistance and permeability due to the metabolism of free arachidonic acid (author's transl)].
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Capillary Permeability; Female; Indomethacin; Male; Pulmonary Circulation; Rabbits; Vascular Resistance | 1981 |
Biphasic dose-response relationship for acetylcholine in the chick jugular vein.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Chickens; Dose-Response Relationship, Drug; Indomethacin; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Parasympathomimetics | 1981 |
Pharmacological studies of anthralin erythema.
Topics: Anthracenes; Anthralin; Aspirin; Betamethasone Valerate; Chlorpheniramine; Erythema; Female; Humans; Indomethacin; Male; Psoriasis; Scopolamine; Skin | 1981 |
A role for prostaglandins E in LH-induced cholesterol depletion in rabbit ovarian follicles.
Topics: Animals; Aspirin; Cholesterol; Female; Indomethacin; Luteinizing Hormone; Meclofenamic Acid; Ovarian Follicle; Prostaglandins E; Prostaglandins F; Rabbits | 1981 |
Mechanisms of Forssman-induced bronchospasm and their inhibition.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Complement System Proteins; Forssman Antigen; Guinea Pigs; Immune Sera; Indomethacin; Neuraminidase; Pressure; Salicylates; Sulfinpyrazone | 1981 |
High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen.
Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Diflunisal; Humans; Indoles; Indomethacin; Indoprofen; Isoindoles; Phenylbutyrates; Salicylates | 1981 |
Anti-inflammatory testing methods: comparative evaluation of mice and rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Cyproheptadine; Edema; Female; Flufenamic Acid; Granuloma; Indomethacin; Mice; Prednisolone; Rats; Rats, Inbred Strains; Species Specificity | 1981 |
Gastric cytoprotection by sodium salicylate.
Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; Male; Rats; Salicylates; Salicylic Acid; Stomach Ulcer; Structure-Activity Relationship | 1981 |
Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat.
Topics: Animals; Aspirin; Embryo Implantation; Female; Ibuprofen; Indomethacin; Injections; Pregnancy; Prostaglandin Antagonists; Rats; Time Factors; Uterus | 1981 |
Further investigations on potassium-induced automaticity of isolated human renal artery.
Topics: Adult; Aged; Aspirin; Bradykinin; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Potassium; Prostaglandins; Quinacrine; Renal Artery; Tranylcypromine | 1981 |
Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets.
Topics: Adenosine Diphosphate; Adult; Antibodies; Aspirin; Blood Platelets; Complement Fixation Tests; Dipyridamole; Female; Heparin; Humans; Indomethacin; Male; Malondialdehyde; Middle Aged; Platelet Aggregation; Platelet Factor 3; Thrombocytopenia; Thromboxane B2 | 1981 |
Drugs, gastritis, and peptic ulcer.
Topics: Acetaminophen; Animals; Aspirin; Bicarbonates; Cimetidine; Duodenitis; Gastric Acid; Gastric Mucosa; Gastritis; Humans; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Peptic Ulcer; Prostaglandins; Rats; Tablets, Enteric-Coated | 1981 |
[Effect of aspirin, indomethacin and imidazole on thrombus formation at the site of a vascular wall injury by a laser ray].
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Lasers; Male; Mesenteric Veins; Rats; Thrombosis; Venules | 1981 |
Study of antiulcer activity of aqueous extract of leaves of Pyrenacantha staudtii (family Icacinaceae) using various models of experimental gastric ulcer in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Female; Indomethacin; Male; Nigeria; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Stomach Ulcer | 1981 |
Effect of antiprostaglandin drugs on human blood--aqueous barrier.
Topics: Aged; Aqueous Humor; Aspirin; Cataract; Cataract Extraction; Eye Proteins; Female; Humans; Indomethacin; Male; Middle Aged; Prostaglandin Antagonists | 1981 |
Effective of acetylsalicylic acid, indomethacin, phenylbutazone, paracetamol, ibuprofen and naproxen on canine gastric mucosa: a histological and ultrastructural study.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Gastric Mucosa; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1981 |
Effects of N-acetyl-L-carnosine aluminum (CL-1700) on various acute gastric lesions and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dipeptides; Gastric Mucosa; Indomethacin; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Stomach; Stomach Ulcer; Stress, Physiological | 1981 |
The modulation of inflammation by the acute phase reaction in adjuvant arthritis in rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Blood Proteins; Blood Sedimentation; Dexamethasone; Female; Indomethacin; Inflammation; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Trypsin Inhibitors | 1981 |
Effects of prostaglandins and their precursors in some tests of hemostatic function.
Topics: Animals; Aspirin; Guinea Pigs; Hemostasis; Indomethacin; Male; Oils; Platelet Aggregation; Prostaglandins | 1981 |
Lactose intolerance.
Topics: Aspirin; Child; Humans; Ibuprofen; Indomethacin; Infant; Lactose Intolerance; Prostaglandins | 1980 |
Effect of inhibitors of the arachidonate pathway on the release of granule contents from rabbit platelets adherent to collagen.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cytoplasmic Granules; In Vitro Techniques; Indomethacin; Platelet Adhesiveness; Platelet Aggregation; Rabbits; Serotonin | 1980 |
Renal prostaglandins and sodium balance in the rabbit: lack of effect of aspirin-like drugs.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Diet, Sodium-Restricted; Female; Indomethacin; Kidney; Mineralocorticoid Receptor Antagonists; Naproxen; Potassium; Prostaglandins E; Prostaglandins F; Rabbits; Sodium | 1980 |
Relationship of plasma anti-heparin activity and platelet survival time in coronary disease.
Topics: Aspirin; Blood Coagulation Factors; Blood Platelets; Cell Survival; Coronary Disease; Dipyridamole; Double-Blind Method; Humans; Indomethacin; Male; Platelet Factor 4; Sulfinpyrazone; Time Factors | 1980 |
Intravenous indomethacin and aspirin reduce basal gastric mucosal blood flow in dogs.
Topics: Animals; Aspirin; Dogs; Gastric Mucosa; Indomethacin; Regional Blood Flow; Stomach; Wakefulness | 1980 |
Adult Still's disease associated with pregnancy.
Topics: Adult; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Prednisone; Pregnancy; Pregnancy Complications; Remission, Spontaneous | 1980 |
Ionic and osmotic influence on prostaglandin release from the gill tissue of a marine bivalve, Modiolus demissus.
Topics: Animals; Aspirin; Gills; Indomethacin; Magnesium; Mercaptoethanol; Mollusca; Osmolar Concentration; Prostaglandins; Radioimmunoassay; Sodium; Water-Electrolyte Balance | 1980 |
[Prostaglandin inhibitors and their use in the obstetrical and gynecological clinic].
Topics: Animals; Aspirin; Ethanol; Female; Fertility; Genital Diseases, Female; Humans; In Vitro Techniques; Indomethacin; Pregnancy; Pregnancy Complications; Prostaglandin Antagonists; Prostaglandins; Uterine Contraction | 1980 |
Significance of prostaglandins in the regulation of cyclic events in the ovary and uterus.
Topics: Animals; Aspirin; Female; Humans; Indomethacin; Luteinizing Hormone; Luteolysis; Menstruation; Menstruation Disturbances; Nucleotides, Cyclic; Ovarian Follicle; Ovary; Ovulation; Prostaglandins; Rats; Uterus | 1980 |
Effects of selected drugs on serum digoxin concentration in dogs.
Topics: Acetaminophen; Animals; Aspirin; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ibuprofen; Indomethacin; Male; Metabolic Clearance Rate; Quinidine; Quinine; Time Factors | 1980 |
Effects of 16, 16-dimethyl prostaglandin E2 methyl ester on aspirin-and indomethacin-induced gastrointestinal lesions in dogs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Dogs; Gastric Mucosa; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Male; Prostaglandins E, Synthetic; Stomach Diseases; Time Factors | 1980 |
Dorsal root vasodilatation in cat skeletal muscle.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Cats; Electric Stimulation; Evoked Potentials; Female; Guanethidine; Hindlimb; Indomethacin; Muscles; Spinal Nerve Roots; Vasodilation | 1980 |
Indomethacin, salicylates and prostaglandin binding.
Topics: Arthritis, Rheumatoid; Aspirin; Humans; Indomethacin; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Protein Binding; Salicylates; Serum Albumin | 1980 |
Human benign breast disease: relationships between prostaglandin E2, steroid hormones, and thermographic effects of the inhibitors of PG biosynthesis.
Topics: Adult; Aspirin; Breast Diseases; Breast Neoplasms; Corpus Luteum; Estradiol; Female; Humans; Indomethacin; Menstruation; Progesterone; Prostaglandin Antagonists; Prostaglandins E; Thermography | 1980 |
Clinical applications.
Topics: Abortion, Induced; Aspirin; Blood Pressure; Cardiovascular Diseases; Cervix Uteri; Digestive System; Female; Gastrointestinal Motility; Humans; Indomethacin; Labor, Induced; Menstruation; Menstruation Disturbances; Pregnancy; Pregnancy Trimester, Second; Prostaglandins; Prostaglandins E; Thrombosis; Uterine Contraction | 1980 |
Adult Still's disease.
Topics: Adolescent; Adult; Arthritis, Juvenile; Aspirin; Blood Sedimentation; Female; Hemoglobins; Humans; Immunoglobulins; Indomethacin; Leukocyte Count; Male | 1980 |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons.
Topics: Animals; Arthropod Venoms; Aspirin; Black Widow Spider; Catecholamines; Clonidine; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Neurons; Norepinephrine; Potassium; Prostaglandins; Rats; Spider Venoms; Sympathetic Nervous System | 1980 |
Arachidonic acid-induced malondialdehyde formation in rat platelets. Kinetic aspects and inhibition by acetylsalicylic acid and indomethacin.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; In Vitro Techniques; Indomethacin; Kinetics; Male; Malonates; Malondialdehyde; Rats; Time Factors | 1980 |
Newer drug therapies for headache.
Topics: Antidepressive Agents; Aspirin; Bromocriptine; Clonidine; Cluster Headache; Dipyridamole; Headache; Humans; Indomethacin; Lithium; Migraine Disorders; Pizotyline; Prednisone; Propranolol | 1980 |
The effect of anti-inflammatory drugs on glycosaminoglycan sulphation in pig cartilage.
Topics: Animals; Aspirin; Cartilage; Dose-Response Relationship, Drug; Glycosaminoglycans; Hydrocortisone; Indomethacin; Sulfates; Sulfur Radioisotopes; Swine | 1980 |
Dextro-phenylalanine inhibits potassium-evoked 3H-noradrenaline release from hypothalamus but not of 3H-dopamine from rat caudate nucleus.
Topics: Animals; Aspirin; Calcium; Caudate Nucleus; Dopamine; Hypothalamus; In Vitro Techniques; Indomethacin; Male; Norepinephrine; Occipital Lobe; Phenylalanine; Potassium; Prostaglandins; Rats | 1980 |
Comparison of the effects of aspirin, indomethacin and tartrazine on dynamic pulmonary compliance and flow resistance in the guinea pig.
Topics: Airway Resistance; Anesthesia; Animals; Aspirin; Azo Compounds; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung Compliance; Tartrazine; Urethane | 1980 |
1-arachidonyl-monoglyceride causes platelet aggregation: indirect evidence for an acylglycerol acylhydrolase involvement in the release of arachidonic acid for prostaglandin synthesis.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Glycerides; Humans; Indomethacin; Liposomes; Lysophospholipase; Phosphatidylcholines; Phospholipases; Platelet Aggregation; Prostaglandins | 1980 |
Evaluation of the role of the F prostaglandins in canine bile flow.
Topics: Animals; Aspirin; Bile; Cholecystectomy; Dogs; Indomethacin; Liver; Prostaglandins F | 1980 |
Effect of prostaglandins & inhibitors of prostaglandin biosynthesis on oviposition in the silkmoth Bombyx mori.
Topics: Animals; Aspirin; Bombyx; Female; Indomethacin; Oviposition; Prostaglandins E; Prostaglandins F | 1980 |
Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist.
Topics: Agranulocytosis; Arachidonic Acids; Aspirin; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Indomethacin; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phenylbutazone; Sulfinpyrazone | 1980 |
[Cytoprotection. A new fashion or real progress?].
Topics: Animals; Aspirin; Gastric Mucosa; Gastritis; Humans; Indomethacin; Prostaglandins E, Synthetic; Rats; Stomach Ulcer | 1980 |
Prolonged bleeding time in Aleutian mink associated with a cyclo-oxygenase-independent aggregation defect and nucleotide deficit in blood platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspirin; Bleeding Time; Blood Platelet Disorders; Blood Platelets; Chediak-Higashi Syndrome; Collagen; Female; Indomethacin; Male; Mink; Oxygenases; Platelet Aggregation; Platelet Function Tests | 1980 |
Inhibition of erythromycin lactobionate-induced writhing by analgesic drugs.
Topics: Analgesics; Animals; Aspirin; Codeine; Dextropropoxyphene; Erythromycin; Indomethacin; Male; Mice; Morphine; Nalorphine; Naloxone; Pain; Phenylbutazone | 1980 |
Effect of intra-articular papain, acetylsalicylic acid, indomethacin, prostaglandin and alcohol on the articular cartilage of rabbit knees.
Topics: Animals; Aspirin; Cartilage, Articular; Ethanol; Indomethacin; Injections, Intra-Articular; Knee Joint; Papain; Prostaglandins; Prostaglandins B; Rabbits | 1980 |
Indomethacin and aspirin: effect of nonsteroidal anti-inflammatory agents on the rate of fracture repair in the rat.
Topics: Animals; Aspirin; Cartilage; Dose-Response Relationship, Drug; Fractures, Bone; Indomethacin; Male; Pseudarthrosis; Radius Fractures; Rats; Ulna Fractures; Wound Healing | 1980 |
Chronic use of aspirin versus indomethacin during non-thrombotic myocardial ischemia: effects on survival.
Topics: Animals; Aspirin; Coronary Disease; Dogs; Electrocardiography; Hemodynamics; Indomethacin; Male; Potassium; Sodium; Water | 1980 |
Peptic ulcer: epidemiology, nutritional aspects, drugs, smoking, alcohol, and diet.
Topics: Adrenal Cortex Hormones; Alcoholic Beverages; Aspirin; Feeding Behavior; Gastric Mucosa; Hormones; Humans; Indomethacin; Peptic Ulcer; Risk; Smoking | 1980 |
Malondialdehyde formation in rat platelet-rich plasma. II. Modification of the reaction kinetics by aspirin and indomethacin in vitro.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Indomethacin; Kinetics; Male; Malonates; Malondialdehyde; Rats; Thrombin | 1980 |
Lymphocyte traffic through antigen-stimulated lymph nodes. II. Role of Prostaglandin E2 as a mediator of cell shutdown.
Topics: Animals; Antigen-Antibody Complex; Antigens, Viral; Arachidonic Acids; Aspirin; Indomethacin; Lymph Nodes; Lymphocytes; Prostaglandins E; Sheep; T-Phages; Tuberculin | 1981 |
[Cytoprotection: a new principle in ulcer therapy?].
Topics: Aspirin; Carbenoxolone; Cimetidine; Gastric Mucosa; Humans; Indomethacin; Peptic Ulcer; Prostaglandins, Synthetic | 1980 |
Indomethacin but not aspirin inhibits basal and stimulated lipolysis in rabbit kidney.
Topics: Animals; Arachidonic Acids; Aspirin; Fatty Acids; Indomethacin; Kidney; Kidney Medulla; Lipolysis; Perfusion; Phospholipases A; Phospholipases A2; Prostaglandins; Rabbits | 1980 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Penicillamine; Phenylbutazone; Thrombocytopenia | 1980 |
Effects of aspirin and acetaminophen in pregnancy and in the newborn.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Aspirin; Blood Platelets; Female; Fetus; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Placenta; Pregnancy; Prostaglandins; Pulmonary Circulation; Rabbits; Rats | 1981 |
The effect of aspirin and indomethacin on prostacyclin and thromboxane production by placental tissue incubated with immunoglobulin G fractions from patients with lupus anticoagulant.
Topics: Antibodies, Antiphospholipid; Aspirin; Epoprostenol; Female; Humans; Immunoglobulin G; Indomethacin; Kinetics; Lupus Coagulation Inhibitor; Placenta; Pregnancy; Thromboxane B2 | 1995 |
Prostaglandin D2 and endothelin-1 induce the production of prostaglandin F2 alpha, 9 alpha, 11 beta-prostaglandin F2, prostaglandin E2, and thromboxane in capillary endothelium of human brain.
Topics: 1-Methyl-3-isobutylxanthine; Aspirin; Brain; Capillaries; Cells, Cultured; Dexamethasone; Dinoprost; Dinoprostone; Endothelins; Endothelium, Vascular; Humans; Indomethacin; Prostaglandin D2; Thromboxane B2 | 1993 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effect of NSAIDs on the chemotaxis induced by substance P on human monocytes and polymorphonuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Indomethacin; Leukocytes; Monocytes; Neutrophils; Piroxicam; Substance P | 1993 |
Effect of nonsteroidal anti-inflammatory drugs on LFA-1 and ICAM-1 expression in gastric mucosa.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Adhesion Molecules; Gastric Mucosa; Immunohistochemistry; Indomethacin; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Male; Misoprostol; Rats; Rats, Inbred Strains; Staining and Labeling | 1994 |
Dilator prostanoid-induced cyclic AMP formation and release by cerebral microvascular smooth muscle cells: inhibition by indomethacin.
Topics: 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Animals, Newborn; Aspirin; Brain; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Enzyme Activation; Iloprost; In Vitro Techniques; Indomethacin; Microcirculation; Muscle, Smooth, Vascular; Receptors, Epoprostenol; Receptors, Prostaglandin; Signal Transduction; Swine | 1995 |
Influence of anti-inflammatory treatments on experimental infection of rats with Fasciola hepatica: changes in serum levels of inflammatory markers during the early stages of fasciolosis.
Topics: Acute-Phase Proteins; Analysis of Variance; Animals; Antibodies, Helminth; Antibody Formation; Antigens, Helminth; Aspirin; Biomarkers; Complement C3; Cyclosporine; Dexamethasone; Fasciola hepatica; Fascioliasis; Female; Fibrinogen; Indomethacin; Inflammation; Leukocyte Count; Male; Platelet Count; Rats; Rats, Wistar; Time Factors | 1994 |
Effects of aspirin and indomethacin on ventricular arrhythmias--comparative study.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Blood Pressure; Cardiac Complexes, Premature; Cause of Death; Heart Block; Heart Rate; Indomethacin; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rabbits; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Function | 1994 |
Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression; Ibuprofen; Indomethacin; Isoenzymes; Kinetics; Macrophages, Alveolar; Nitric Oxide Synthase; Rats; Sodium Salicylate | 1995 |
Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Aspirin; Cell Adhesion; Cell Adhesion Molecules; Cytoplasmic Granules; Diclofenac; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Enzymes; Humans; Indomethacin; Inflammation; Intercellular Adhesion Molecule-1; L-Selectin; Neutrophils; Piroxicam | 1995 |
Inhibitory effect of indomethacin on prostacyclin receptor-mediated cerebral vascular responses.
Topics: Animals; Animals, Newborn; Arterioles; Aspirin; Cerebrovascular Circulation; Hypercapnia; Iloprost; Indomethacin; Isoproterenol; Pia Mater; Receptors, Epoprostenol; Receptors, Prostaglandin; Swine | 1995 |
The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
Topics: Acetaminophen; Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cell-Free System; Dinoprostone; Dose-Response Relationship, Drug; Electron Transport Complex IV; Enzyme Induction; Gene Expression; Hydrocortisone; Indomethacin; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase; Sodium Salicylate | 1995 |
Functional study on vasodilator effects of prostaglandin E2 in the newborn pig cerebral circulation.
Topics: Animals; Animals, Newborn; Arterioles; Aspirin; Cerebral Cortex; Cerebrovascular Circulation; Cyclic AMP; Dinoprostone; Iloprost; Indomethacin; Receptors, Epoprostenol; Receptors, Prostaglandin; Swine; Vasodilator Agents | 1995 |
Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Adhesion; Dinoprostone; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Indomethacin; Leukocytes; Leukotriene C4; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfhydryl Compounds; Tetrazoles; Thiophenes | 1995 |
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Neoplasms; Cell Division; Female; Glioma; Hydrogen-Ion Concentration; Indomethacin; Male; Neoplasm Proteins; Neoplasm Transplantation; Piroxicam; Rats; Rats, Inbred F344; Salicylates; Tumor Cells, Cultured | 1995 |
Anti-thrombotic activity of KBT-3022 in experimental models of thrombosis.
Topics: Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Extracorporeal Circulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred Strains; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Silver Nitrate; Thiazoles; Thrombosis; Ticlopidine | 1995 |
Anti-ulcer effect of the hot water extract of black tea (Camellia sinensis).
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; India; Indomethacin; Plant Extracts; Prostaglandins; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Tea; Water | 1995 |
Activation of 2-aminofluorene by prostaglandin endoperoxide H synthase-2.
Topics: Animals; Aspirin; Carcinogens; DNA Adducts; DNA, Complementary; Endothelium, Vascular; Female; Fluorenes; Gene Expression; Humans; Indomethacin; Isoenzymes; Male; Placenta; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Tetradecanoylphorbol Acetate; Transfection; Umbilical Veins | 1995 |
Plasma 8-epi-PGF2 alpha levels are elevated in individuals with non-insulin dependent diabetes mellitus.
Topics: Adult; Aspirin; Chromatography, Gas; Diabetes Mellitus, Type 2; Dinoprost; Esterification; Humans; Indomethacin; Mass Spectrometry; Models, Chemical; Oxidative Stress | 1995 |
Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fish Oils; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Hypothermia; Indomethacin; Male; Pylorus; Rats; Rats, Wistar; Reserpine; Sodium Hydroxide; Stomach Ulcer | 1995 |
Plasminogen activator inhibitor type 2 prevents programmed cell death of human macrophages infected with Mycobacterium avium, serovar 4.
Topics: Apoptosis; Aspirin; Cells, Cultured; Dinoprostone; DNA Damage; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Macrophages; Mycobacterium avium; Piroxicam; Plasminogen Activator Inhibitor 2; RNA, Messenger; Time Factors | 1995 |
Effects of pethidine, acetylsalicylic acid, and indomethacin on pain and behavior in the mole-rat.
Topics: Aggression; Analgesics; Animals; Aspirin; Behavior, Animal; Dose-Response Relationship, Drug; Indomethacin; Meperidine; Naloxone; Pain Measurement; Psychomotor Performance; Reaction Time; Rodentia | 1993 |
JB-9322, a new selective histamine H2-receptor antagonist with potent gastric mucosal protective properties.
Topics: Animals; Aspirin; Ethanol; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Piperidines; Ranitidine; Rats; Rats, Wistar; Stomach Diseases | 1995 |
PGE2 involvement in experimental infection with Trypanosoma cruzi subpopulations.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Cell Adhesion; Chagas Disease; Dinoprostone; Indomethacin; Leukocyte Count; Male; Mice; Mice, Inbred C3H; T-Lymphocytes; Trypanosoma cruzi | 1995 |
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division; Cell Line; Cell Survival; Dog Diseases; Dogs; Drug Screening Assays, Antitumor; Hydroxyurea; Indomethacin; Melanoma; Piroxicam; Sarcoma; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Renal and systemic-hemodynamic response to isovolemic exchange transfusion with hemoglobin cross-linked with bis (3,5-dibromosalicyl) fumarate or albumin.
Topics: Animals; Aspirin; Blood Substitutes; Exchange Transfusion, Whole Blood; Glomerular Filtration Rate; Half-Life; Hemodynamics; Hemoglobins; Indomethacin; Kidney; Macromolecular Substances; Rats; Rats, Sprague-Dawley; Serum Albumin | 1995 |
Aspirin enhances thermotolerance in human erythroleukemic cells: an effect associated with the modulation of the heat shock response.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature Regulation; Cell Division; DNA; DNA-Binding Proteins; Heat Shock Transcription Factors; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Indomethacin; Leukemia, Erythroblastic, Acute; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Protection by nitecapone against sodium taurocholate-induced damage to cultured gastric cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Ulcer Agents; Aspirin; Catechols; Cell Line; Cell Survival; Cells, Cultured; Dinoprostone; Epithelial Cells; Epithelium; Gastric Mucosa; Humans; Indomethacin; Pentanones; Rats; Rats, Wistar; Staining and Labeling; Taurocholic Acid | 1993 |
Effect of indomethacin and aspirin on the TNF-alpha-induced priming and protein tyrosyl phosphorylation of human neutrophils.
Topics: Animals; Aspirin; Azides; Electrophoresis, Polyacrylamide Gel; Granulocyte Colony-Stimulating Factor; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sodium Azide; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 1993 |
Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Aspirin; Base Sequence; Carbon Radioisotopes; Cells, Cultured; Endothelium; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Masoprocol; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Recombinant Proteins; RNA; RNA, Messenger | 1993 |
Effect of etodolac on prostaglandin E2 biosynthesis, active oxygen generation and bradykinin formation.
Topics: Animals; Aspirin; Bradykinin; Bromelains; Cartilage, Articular; Cell Line; Concanavalin A; Depression, Chemical; Diclofenac; Dinoprostone; Dogs; Etodolac; Gastric Mucosa; Guinea Pigs; Indomethacin; Interleukin-1; Ketoprofen; Kidney; Naproxen; Oxygen; Pain; Piroxicam; Rabbits; Rats | 1994 |
Effects of angiotensin II on isolated rabbit afferent arterioles.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arterioles; Aspirin; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Prostaglandins; Rabbits; Renal Circulation; Tetrazoles; Vascular Resistance | 1994 |
Production of PGE2 and 15-HETE by fibrosarcoma cells.
Topics: Animals; Arachidonic Acid; Aspirin; Calcimycin; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Dinoprostone; Fibrosarcoma; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Effect of the low molecular weight heparin/non steroidal anti-inflammatory drugs association on an experimental thrombosis induced by laser.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Therapy, Combination; Indomethacin; Injections, Subcutaneous; Ketoprofen; Lasers; Male; Nadroparin; Piroxicam; Platelet Aggregation; Rats; Rats, Wistar; Thrombolytic Therapy; Thrombosis | 1995 |
The effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the spontaneously beating isolated auricles of the rabbit heart.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atrial Function; Female; Heart Atria; In Vitro Techniques; Indomethacin; Male; Myocardial Contraction; Rabbits; Sinoatrial Node | 1994 |
Effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion in pylorus-ligated rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Ibuprofen; Indomethacin; Ligation; Male; Pepsinogens; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 1995 |
Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
Topics: Adaptation, Physiological; Animals; Aspirin; Dinoprostone; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Male; Naproxen; Ornithine Decarboxylase; Peroxidase; Rats; Rats, Wistar | 1995 |
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins.
Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Drug Tolerance; Ibuprofen; Imidazoles; Indomethacin; Lactates; Lipopolysaccharides; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic; Thromboxanes | 1995 |
An experimental model of osteoarthritis in rabbit.
Topics: Animals; Aspirin; Disease Models, Animal; Indomethacin; Male; Osteoarthritis; Rabbits | 1994 |
Reduction in human neutrophil superoxide anion generation by n-3 polyunsaturated fatty acids: role of cyclooxygenase products and endothelium-derived relaxing factor.
Topics: Arachidonic Acid; Arginine; Aspirin; Depression, Chemical; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Indomethacin; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Respiratory Burst; Superoxides | 1994 |
Purification and characterization of L-amino acid oxidase from king cobra (Ophiophagus hannah) venom and its effects on human platelet aggregation.
Topics: Alprostadil; Amino Acid Oxidoreductases; Animals; Antimycin A; Aspirin; Blood Coagulation Tests; Blood Platelets; Catalase; Chromatography, Gel; Chromatography, Ion Exchange; Drug Interactions; Edetic Acid; Elapid Venoms; Electrophoresis, Polyacrylamide Gel; Heparin; Hirudins; Humans; Hydrogen Peroxide; Indomethacin; Isoelectric Point; L-Amino Acid Oxidase; Molecular Weight; Nitroprusside; Platelet Aggregation; Quinacrine; Thromboxane A2; Verapamil | 1994 |
Cholecystokinin is a potent protective agent against alcohol-induced gastric injury in the rat. Role of endogenous prostaglandins.
Topics: Animals; Aspirin; Benzodiazepinones; Cholecystokinin; Devazepide; Ethanol; Female; Gastric Mucosa; Indomethacin; Phenylurea Compounds; Premedication; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1995 |
Aspirin inhibits secretagogue-stimulated and postprandial pancreatic exocrine secretion in conscious rats.
Topics: Animals; Aspirin; Cholecystokinin; Dinoprostone; Food; Indomethacin; Male; Pancreas; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Secretin; Stimulation, Chemical | 1995 |
Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema.
Topics: Ajmaline; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Carbon Radioisotopes; Carrageenan; Edema; Humans; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Shock | 1993 |
Studies on antiulcer drugs. 7. 2-Guanidino-4-pyridylthiazoles as histamine H2-receptor antagonists with potent gastroprotective effects against nonsteroidal antiinflammatory drug-induced injury.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Blood Flow Velocity; Dogs; Gastric Acid; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; Indomethacin; Male; Molecular Structure; Myocardial Contraction; Rabbits; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiazoles | 1994 |
Involvement of leukotrienes in allergic inflammation in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Autacoids; Edema; Immunization; Immunization, Secondary; Indomethacin; Inflammation; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Mice; Receptors, Leukotriene; Tetrazoles | 1994 |
Synthesis and anti-inflammatory properties of 1,2-dialkoxy-4-(3-dimethylaminopropionyl)benzenes and their 5-halogeno derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Edema; Foot Injuries; Indomethacin; Lethal Dose 50; Lysine; Male; Mice; Mice, Inbred BALB C; Peritonitis; Propiophenones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship | 1994 |
A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats.
Topics: Animals; Aspirin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Leukotrienes; Male; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spin Labels; Stomach Ulcer; Superoxide Dismutase | 1994 |
Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice.
Topics: Animals; Anxiety; Aspirin; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; Indomethacin; Inflammation; Male; Mice; Morphine; Pain; Pain Threshold; Receptors, GABA-A | 1994 |
Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury.
Topics: Analysis of Variance; Animals; Aspirin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind Method; Drug Therapy, Combination; Female; Indomethacin; Lipopolysaccharides; Motor Activity; Pregnenolone; Rats; Rats, Sprague-Dawley; Salmonella enteritidis; Spinal Cord; Spinal Cord Injuries | 1994 |
Antinociceptive, anti-inflammatory and antipyretic effects of lapidin, a bicyclic sesquiterpene.
Topics: Analgesics; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Edema; Indomethacin; Male; Mice; Pain; Physical Stimulation; Plants, Medicinal; Sesquiterpenes | 1994 |
Effect of 1,6-dihydro-2-[2-(2-methylpropoxy)anilino]-6-oxo-5-pyrimidinecarboxylic acid on gastric mucosal defensive factors and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Epithelial Cells; Epithelium; Ethanol; Gastric Acid; Gastric Mucosa; Hexosamines; Histamine; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mucus; Pentagastrin; Pyrimidines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach | 1994 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Bromodeoxyuridine; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Muscle, Smooth; Trachea | 1994 |
In vitro activation of cyclo-oxygenase in the rabbit carotid body: effect of its blockade on [3H]catecholamine release.
Topics: Animals; Aspirin; Carbon Dioxide; Carotid Body; Catecholamines; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Prostaglandin-Endoperoxide Synthases; Rabbits | 1994 |
Possible involvement of arachidonic acid and eicosanoids in metamorphic events in Hydractinia echinata (Coelenterata; Hydrozoa).
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aspirin; Carbon Radioisotopes; Eicosanoids; Gas Chromatography-Mass Spectrometry; Hydra; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Masoprocol; Metamorphosis, Biological; Phospholipids | 1994 |
Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity.
Topics: Adult; Analysis of Variance; Aspirin; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Humans; Indomethacin; Sulindac; Time Factors; Ultrasonography; Vasoconstriction; Vasodilation | 1994 |
Novel anti-inflammatory plant labdanes: comparison of in vitro properties with aspirin and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diterpenes; Eicosanoids; Humans; Indomethacin; Naphthols; Neutrophils; Phospholipases A; Phospholipases A2; Plant Extracts; Platelet Aggregation; Rats; Reactive Oxygen Species; Sodium Salicylate; Superoxides; Synovial Fluid; Terpenes | 1994 |
Characteristics of the passive 45Ca2+ transport by human blood platelets. Their dependence on the monovalent cation composition of the suspension media.
Topics: Aspirin; Blood Platelets; Calcium; Calcium Channel Blockers; Choline; Female; Humans; Indomethacin; Ion Transport; Male; Membrane Potentials; Potassium; Sodium; Veratridine | 1994 |
Effects of NG-monomethyl-L-arginine, indomethacin, and aspirin on the vasodepressor response to low doses of endothelin-1 and endothelin-3 in rats.
Topics: Animals; Arginine; Aspirin; Blood Pressure; Endothelins; Indomethacin; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Vascular Resistance | 1994 |
Protection by indomethacin against the lethality and hepatotoxicity of phalloidin in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Female; Ibuprofen; Indomethacin; Liver; Liver Diseases; Mice; Microscopy, Electron; Phalloidine; Time Factors | 1994 |
Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem.
Topics: Animals; Antacids; Aspirin; Biological Availability; Butadienes; Depression, Chemical; Diarrhea; Dogs; Drug Carriers; Ethanol; Female; Gastric Mucosa; Hypromellose Derivatives; Indomethacin; Intestinal Diseases; Male; Methylcellulose; Misoprostol; Polymers; Rats; Rats, Inbred Strains; Stomach Diseases | 1994 |
The augmentation of lymphokine-activated killer cell activity by indomethacin in vitro is not mediated by prostaglandin E2 suppression.
Topics: Aspirin; Cells, Cultured; Cytotoxicity, Immunologic; Dinoprostone; Humans; Indomethacin; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukocytes, Mononuclear; Mefenamic Acid; Neoplasms; Recombinant Proteins; Tumor Cells, Cultured | 1993 |
Aspirin-like drugs inhibit neuronally evoked responses in isolated guinea-pig ileum.
Topics: Acetylcholine; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzydamine; Cyclooxygenase Inhibitors; Guinea Pigs; Ileum; Indomethacin; Isotonic Contraction; Male; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Receptors, Opioid; Salicylates; Salicylic Acid; Sincalide | 1993 |
Ca2+ influx via T-type channels modulates PDGF-induced replication of mouse fibroblasts.
Topics: Animals; Aspirin; Caffeic Acids; Calcium; Calcium Channels; Cell Division; Cell Line; Evoked Potentials; Fibroblasts; Indomethacin; Kinetics; Masoprocol; Membrane Potentials; Mice; Mice, Inbred C3H; Platelet-Derived Growth Factor; S Phase; Time Factors | 1993 |
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blotting, Western; Cattle; Cell Line; Cell Survival; Cyclooxygenase Inhibitors; Eicosanoids; Endothelium, Vascular; Enzyme Induction; Ibuprofen; Indomethacin; Kinetics; Macrophages; Mice; Models, Biological; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate | 1993 |
Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage.
Topics: Administration, Oral; Animals; Arthritis; Aspirin; Female; Gastric Mucosa; Indoles; Indomethacin; Injections, Subcutaneous; Intestinal Mucosa; Leukotriene Antagonists; Leukotriene C4; Lipoxygenase Inhibitors; Rats; Rats, Inbred Lew; Stomach; Stomach Ulcer; Swine | 1993 |
Dirofilaria immitis: heartworm products contract rat trachea in vitro.
Topics: Acetylcholine; Animals; Aspirin; Culture Techniques; Cyclooxygenase Inhibitors; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Epithelium; Indomethacin; Male; Muscle Contraction; Prostaglandin-Endoperoxide Synthases; Random Allocation; Rats; Rats, Sprague-Dawley; Trachea | 1994 |
The influence of different amounts of n-3 polyunsaturated fatty acids on bleeding time and in vivo vascular reactivity.
Topics: Animals; Arachidonic Acids; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Blood Vessels; Dose-Response Relationship, Drug; Erythrocytes; Fatty Acids; Fatty Acids, Omega-3; Hematocrit; Indomethacin; Male; Norepinephrine; Rats; Rats, Wistar | 1994 |
Effect of prostaglandin synthesis inhibitors on spontaneous and endotoxin-induced abortion in mice.
Topics: Abortion, Spontaneous; Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Indomethacin; Lipopolysaccharides; Male; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Mice, Inbred DBA; Pregnancy; Prostaglandin Antagonists; Species Specificity | 1993 |
Arachidonic acid metabolism by isolated and cultured middle ear epithelial cells from the chinchilla.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Cell Separation; Cells, Cultured; Chinchilla; Dinoprost; Dinoprostone; Ear, Middle; Epithelial Cells; Epithelium; Indomethacin; Prostaglandin D2; Thromboxane B2; Time Factors; Tritium | 1993 |
Cyclooxygenase inhibitors prevent the induction of tolerance to the toxic effects of tumor necrosis factor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Protocols; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Immunotherapy; Indomethacin; Lysine; Mice; Mice, Inbred C57BL; Neoplasms; Piroxicam; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Motor effects of indomethacin, morphine or vagal nerve stimulation on the feline small intestine in vivo.
Topics: Animals; Aspirin; Autonomic Nervous System; Cats; Diclofenac; Electric Stimulation; Female; Gastrointestinal Motility; Indomethacin; Jejunum; Male; Morphine; Muscle Contraction; Neuroeffector Junction; Vagus Nerve | 1993 |
Modification by CO2 of endothelin-1-induced contraction of isolated guinea pig trachea.
Topics: Acetylcholine; Animals; Aspirin; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Endothelins; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Indomethacin; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Trachea | 1993 |
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Indomethacin; Isoenzymes; Kinetics; Mice; Prostaglandin-Endoperoxide Synthases | 1993 |
Intrathecal acetylsalicylic acid and indomethacin are not analgesic for a supramaximal stimulus.
Topics: Animals; Aspirin; Indomethacin; Injections, Spinal; Pain; Rabbits | 1993 |
Effect of indomethacin, aspirin, nordihydroguairetic acid, and piperonyl butoxide on cyclophosphamide-induced bladder damage.
Topics: Acrolein; Animals; Aspirin; Cyclophosphamide; DNA; Glutathione; Hemoglobins; Indomethacin; Male; Masoprocol; Mice; Mice, Inbred ICR; Mixed Function Oxygenases; Permeability; Piperonyl Butoxide; Proteins; Solubility; Sulfhydryl Compounds; Urinary Bladder; Urinary Bladder Diseases | 1993 |
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
Topics: Administration, Oral; Administration, Rectal; Administration, Sublingual; Animals; Aspirin; Female; Hydrochloric Acid; Indomethacin; Ligation; Male; Models, Biological; Omeprazole; Peptic Ulcer; Rats; Rats, Wistar | 1993 |
NSAID-induced delay in gastric ulcer healing is not associated with decreased epithelial cell proliferation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Epithelial Cells; Epithelium; Gastric Mucosa; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing | 1995 |
Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Indomethacin; Larva; Male; Morphogenesis; Oesophagostomum; Prostaglandin D2; Prostaglandins; Swine; Thromboxane B2 | 1995 |
Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA, Neoplasm; HT29 Cells; Humans; Indomethacin; Naproxen; Piroxicam; Protein Serine-Threonine Kinases | 1996 |
Prostaglandins modulate the responsiveness of the gastric microcirculation of sodium nitroprusside in cirrhotic rats.
Topics: Analysis of Variance; Animals; Arginine; Aspirin; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Liver Cirrhosis, Experimental; Male; Microcirculation; Misoprostol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Prostaglandins; Rats; Rats, Sprague-Dawley; Stomach; Vasodilator Agents | 1996 |
A new technique for continuous measurement and recording of gastric potential difference in the rat: evaluation of NSAID-induced gastric mucosal damage.
Topics: Analysis of Variance; Animals; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Electrodes; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Pyridines; Rats; Rats, Wistar; Reproducibility of Results; Sucralfate | 1995 |
Gastric mucosal adaptation to diclofenac injury.
Topics: Adaptation, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Gastric Mucosa; Indomethacin; Male; Membrane Potentials; Piroxicam; Rats; Rats, Inbred Strains; Time Factors | 1996 |
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole; Ethanol; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship | 1995 |
Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family.
Topics: 3-Hydroxysteroid Dehydrogenases; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Differentiation; Cholecalciferol; Dexamethasone; Dihydrotestosterone; Down-Regulation; Estradiol; HL-60 Cells; Humans; Indomethacin; Medroxyprogesterone; Monocytes; Naphthol AS D Esterase; Neutrophils; Nitroblue Tetrazolium; Prostaglandins; Tretinoin | 1996 |
Effect of KBT-3022, a new cyclooxygenase inhibitor, on experimental brain edema in vitro and in vivo.
Topics: Animals; Arachidonic Acid; Aspirin; Brain; Brain Edema; Brain Ischemia; Cyclooxygenase Inhibitors; Gerbillinae; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipid Peroxidation; Male; Pyrroles; Thiazoles | 1996 |
Nonsteroidal anti-inflammatory drugs activate carbonic anhydrase by a direct mechanism of action.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Indomethacin; Naproxen; Piroxicam | 1996 |
Effect of cyclo-oxygenase inhibitors and modulators of cyclic AMP formation on lipopolysaccharide-induced neutrophil infiltration in mouse lung.
Topics: Administration, Inhalation; Animals; Antifungal Agents; Aspirin; Bronchoalveolar Lavage Fluid; Cyclic AMP; Cycloheximide; Cyclooxygenase Inhibitors; Disease Models, Animal; Escherichia coli; Indomethacin; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neutrophils; Tumor Necrosis Factor-alpha | 1996 |
Regulation of plasminogen activator inhibitor activity by plasmin in endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Fibrinolysin; Fibrinolysis; Gene Expression Regulation; GTP-Binding Proteins; Humans; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Masoprocol; Pertussis Toxin; Phospholipases A; Phospholipases A2; Piperazines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Quinacrine; Staurosporine; Tissue Plasminogen Activator; Umbilical Veins; Virulence Factors, Bordetella | 1996 |
Nonsteroidal antiinflammatory drugs inhibit cyclooxygenase-2 enzyme activity but not mRNA expression in human macrophages.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Humans; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides | 1996 |
Effects of intravenous nonsteroidal antiinflammatory drugs on a C-fiber reflex elicited by a wide range of stimulus intensities in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Injections, Intravenous; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reflex | 1996 |
A copper-complex reduced gastric damage caused by acetylsalicylic acid and ethanol.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Chelating Agents; Copper; Dose-Response Relationship, Drug; Drug Interactions; Eicosanoids; Enzyme Inhibitors; Ethanol; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroarginine; Organometallic Compounds; Rats; Rats, Sprague-Dawley | 1996 |
Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney.
Topics: Animals; Anticarcinogenic Agents; Aspirin; DNA Adducts; DNA Damage; Indomethacin; Kidney; Kidney Neoplasms; Male; Mice; Ochratoxins; Urinary Bladder; Urinary Bladder Neoplasms | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Smooth muscle contractile action of the venom from the crown-of-thorns starfish, Acanthaster planci.
Topics: Animals; Aspirin; Capillary Permeability; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Lethal Dose 50; Marine Toxins; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Starfish; Uterine Contraction; Uterus | 1996 |
Involvement of prostaglandins in the down-regulation of allergic plasma leakage observed in rats undergoing pleural eosinophilia.
Topics: Animals; Aspirin; Dinoprostone; Down-Regulation; Eosinophils; Female; Hypersensitivity; Indomethacin; Male; Pleurisy; Rats; Rats, Wistar | 1996 |
Two mechanisms for platelet-mediated killing of tumour cells: one cyclo-oxygenase dependent and the other nitric oxide dependent.
Topics: Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Hemoglobins; Humans; Indomethacin; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured | 1996 |
Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat.
Topics: Animals; Aspirin; Benzofurans; Ethanol; Female; Gastritis; Indomethacin; Iodoacetamide; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Peptic Ulcer Hemorrhage; Phenylbutyrates; Propionates; Quinolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1996 |
The anti-inflammatory drug sodium salicylate inhibits nitric oxide formation induced by interleukin-1beta at a translational step, but not at a transcriptional step, in hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Enzyme Induction; Indomethacin; Interleukin-1; Liver; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; RNA, Messenger; Sodium Salicylate; Transcription, Genetic | 1997 |
Differential inhibition of murine prostaglandin synthase-1 and -2 by nonsteroidal anti-inflammatory drugs using exogenous and endogenous sources of arachidonic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Calcimycin; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Indomethacin; Isoenzymes; Kinetics; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides | 1997 |
Inhibitory effects of docosahexaenoic acid on colon carcinoma 26 metastasis to the lung.
Topics: Animals; Antineoplastic Agents; Aspirin; Colonic Neoplasms; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Fatty Acids, Unsaturated; Indomethacin; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oxidation-Reduction; Tumor Cells, Cultured | 1997 |
Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and then reoxygenated.
Topics: Acridines; Aerobiosis; Aspirin; Benzoates; Blood Platelets; Catalase; Cell Hypoxia; Deoxyribose; Free Radical Scavengers; Humans; Hydroxyl Radical; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Mannitol; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase; Superoxides | 1997 |
Effects of nonsteroidal anti-inflammatory drugs on glutathione S-transferases of the rat digestive tract.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cytosol; Digestive System; Dose-Response Relationship, Drug; Enzyme Induction; Esophagus; Glutathione; Glutathione Transferase; Ibuprofen; Indomethacin; Intestines; Isoenzymes; Liver; Male; Organ Specificity; Piroxicam; Rats; Rats, Wistar; Stomach; Substrate Specificity; Sulindac | 1997 |
Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Heme; Hydrogen Peroxide; Indomethacin; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Male; Peroxidase; Photosensitizing Agents; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Prostaglandins H; Protoporphyrins; Sheep; Spectrophotometry, Atomic | 1997 |
Increased serum leukotriene B4 level in the active stage of rheumatoid arthritis in children.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Case-Control Studies; Child; Child, Preschool; Cyclooxygenase Inhibitors; Female; Hemoglobins; Humans; Indomethacin; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prednisolone | 1997 |
Inhibition of activator protein 1 activity and neoplastic transformation by aspirin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Diethylstilbestrol; Genes, jun; Genes, ras; Hydrogen-Ion Concentration; Indomethacin; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Sodium Salicylate; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured | 1997 |
Gastric mucosal injury by nonsteroidal anti-inflammatory drugs is reduced by (R)-alpha-methylhistamine and its pro-drugs in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Acid; Gastric Mucosa; Histamine Agonists; Indomethacin; Male; Methylhistamines; Prodrugs; Rats; Rats, Wistar; Stomach Ulcer | 1997 |
Aspirin, but not sodium salicylate, indomethacin, or nabumetone, reversibly suppresses 1,2-dimethylhydrazine-induced colonic aberrant crypt foci in rats.
Topics: 1,2-Dimethylhydrazine; 16,16-Dimethylprostaglandin E2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Dimethylhydrazines; Indomethacin; Male; Nabumetone; Rats; Rats, Sprague-Dawley; Sodium Salicylate | 1997 |
Platelet activation by a novel solid-phase agonist: effects of VWF immobilized on polystyrene beads.
Topics: Aspirin; Blood Coagulation Disorders; Contusions; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Male; Microspheres; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Sulfonamides; von Willebrand Factor | 1997 |
Expression of recombinant human cyclooxygenase isoenzymes in transfected COS-7 cells in vitro and inhibition by tenoxicam, indomethacin and aspirin.
Topics: Animals; Aspirin; COS Cells; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Piroxicam; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Transfection | 1997 |
Functional stability of hippocampal slices after treatment with cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Cold Temperature; Cyclooxygenase Inhibitors; Electrophysiology; Guinea Pigs; Hippocampus; Histocytological Preparation Techniques; In Vitro Techniques; Indomethacin; Tissue Preservation | 1997 |
Effects of intrathecal or intracerebroventricular administration of nonsteroidal anti-inflammatory drugs on a C-fiber reflex in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Indomethacin; Injections, Intraventricular; Injections, Spinal; Ketoprofen; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reflex | 1997 |
Macrophage-induced nitric oxide and prostanoid dependent relaxation of arterial smooth muscles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arteries; Aspirin; Cells, Cultured; Dogs; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophages, Peritoneal; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Regional differentiation in the rat aorta: effects of cyclooxygenase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Aorta, Abdominal; Aorta, Thoracic; Aspirin; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Prostaglandin H2; Prostaglandins H; Rats; Rats, Sprague-Dawley | 1997 |
Dopamine potentiation of calcium ionophore, A-23187-induced platelet aggregation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Androstadienes; Aspirin; Benzophenanthridines; Calcimycin; Calcium; Chlorpromazine; Diltiazem; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; GTP-Binding Proteins; Haloperidol; Homovanillic Acid; Humans; Indomethacin; Ion Transport; Ionophores; Phenanthridines; Phentolamine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Propranolol; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Dopamine; Serotonin; Signal Transduction; Verapamil; Wortmannin | 1997 |
Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets.
Topics: Aspirin; Blood Platelets; Blotting, Western; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Cytosol; Humans; Indomethacin; Nitric Oxide Synthase; Osmolar Concentration; Thromboxane B2 | 1997 |
Flow- and agonist-mediated nitric oxide- and prostaglandin-dependent dilation in spinal arteries.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arteries; Aspirin; Dinoprostone; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pressure; Prostaglandins; Prostaglandins, Synthetic; Rabbits; Spine; Vasodilation | 1997 |
Mitochondrial damage: a possible mechanism of the "topical" phase of NSAID induced injury to the rat intestine.
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Biomarkers; Butanones; Indomethacin; Intestinal Diseases; Intestine, Small; Male; Microscopy, Electron; Microvilli; Mitochondria, Liver; Nabumetone; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Ulcer; Uncoupling Agents | 1997 |
Effect of n-3 fatty acids on VLDL production by hepatocytes is mediated through prostaglandins.
Topics: Animals; Apolipoproteins B; Aspirin; Diethylcarbamazine; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Indomethacin; Leucine; Lipoproteins, VLDL; Liver; Male; Palmitic Acid; Prostaglandins; Rats; Rats, Sprague-Dawley; Tritium | 1997 |
Discrimination of site-specific alterations in gastrointestinal permeability in the rat.
Topics: Animals; Aspirin; Biological Transport; Cyclooxygenase Inhibitors; Digestive System; Disease Models, Animal; Gastrointestinal Diseases; Indomethacin; Rats; Trinitrobenzenesulfonic Acid | 1998 |
Platelet-derived growth factor reverses the effects induced by NSAIDs on ulcer healing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Gastric Mucosa; Granulation Tissue; Indomethacin; Male; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Stomach Ulcer; Wound Healing | 1997 |
Non-steroidol anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Butanones; Carcinogens; Cell Division; Colon; Colonic Neoplasms; DNA Fragmentation; DNA, Neoplasm; Indomethacin; Male; Nabumetone; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Regression Analysis | 1998 |
Modulation of migration of Oesophagostomum dentatum larvae by inhibitors and products of eicosanoid metabolism.
Topics: Animals; Aspirin; Biological Assay; Cyclooxygenase Inhibitors; Diethylcarbamazine; Dose-Response Relationship, Drug; Eicosanoids; Indomethacin; Larva; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Locomotion; Oesophagostomum; Prostaglandins; Swine | 1998 |
Studies on the possible mechanism of the gastric mucosal protection by Calotropis procera--involvement of 5-lipoxygenase pathway.
Topics: Animals; Anti-Ulcer Agents; Arachidonate 5-Lipoxygenase; Aspirin; Ethanol; Female; Gastric Mucosa; Glycine max; Indomethacin; Ligation; Male; Plant Extracts; Plants, Medicinal; Pylorus; Rats; Stomach Ulcer; Stress, Physiological | 1998 |
Cyclooxygenase inhibition attenuates cholecystokinin-induced gastroprotection.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Gastrointestinal Agents; Indomethacin; Prostaglandins; Rats; Rats, Sprague-Dawley; Sincalide; Time Factors | 1998 |
Antioxidants diminish developmental damage induced by high glucose and cyclooxygenase inhibitors in rat embryos in vitro.
Topics: Acetylcysteine; Animals; Antioxidants; Arachidonic Acid; Aspirin; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Embryo, Mammalian; Embryonic and Fetal Development; Glucose; Indomethacin; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1998 |
Effect of some cyclooxygenase inhibitors on the increase in guanosine 3':5'-cyclic monophosphate induced by NO-donors in human whole platelets.
Topics: Acetophenones; Aspirin; Blood Platelets; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Indoprofen; Nitric Oxide; Nitroprusside; Penicillamine; Phospholipases A; Thromboxane B2 | 1998 |
Prevention of ethanol-induced gastric lesions in rats by wu-bei-san.
Topics: Animals; Aspirin; Calcium Carbonate; Drugs, Chinese Herbal; Ethanol; Gastric Mucosa; Indomethacin; Male; Rats; Rats, Sprague-Dawley; Stomach; Stomach Diseases | 1998 |
Aspirin-like molecules that covalently inactivate cyclooxygenase-2.
Topics: Acetylation; Acetylene; Alkynes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Design; Humans; Indomethacin; Isoenzymes; Macrophages; Membrane Proteins; Mutagenesis, Site-Directed; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Sulfides; Thromboxane B2; Tumor Cells, Cultured | 1998 |
Prodrugs. Part 3. 2-Formylphenyl esters of indomethacin, ketoprofen and ibuprofen and 6-substituted 2-formyl and 2-acylphenyl esters of aspirin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ibuprofen; Indomethacin; Ketoprofen; Male; Prodrugs; Rats; Rats, Wistar | 1998 |
Further insights into the anti-aggregating activity of NMDA in human platelets.
Topics: Aspirin; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; In Vitro Techniques; Indomethacin; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Thromboxane B2 | 1998 |
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2 | 1998 |
The lack of bimodality in the effects of endogenous and exogenous prostaglandins on fat cell lipolysis in rats.
Topics: Adenosine; Adenosine Deaminase; Adipocytes; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Glycerol; Indomethacin; Isoproterenol; Lipolysis; Rats; Rats, Wistar | 1998 |
Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells.
Topics: Antiviral Agents; Aspirin; Cells, Cultured; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytomegalovirus; Cytopathogenic Effect, Viral; Dexamethasone; Dinoprostone; Free Radical Scavengers; Gene Expression Regulation, Viral; Humans; Immediate-Early Proteins; Indomethacin; Isoenzymes; Membrane Proteins; Muscle Proteins; Muscle, Smooth, Vascular; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Sodium Salicylate; Sulfonamides; Transcriptional Activation; Viral Proteins; Virus Replication | 1998 |
Chemical and pharmacological examination of antinociceptive constituents of Wedelia paludosa.
Topics: Abdomen; Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brazil; Dipyrone; Diterpenes; Flavonoids; Indomethacin; Luteolin; Male; Medicine, Traditional; Mice; Pain; Plant Extracts; Plants, Medicinal | 1998 |
Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.
Topics: Aged; Amino Acid Chloromethyl Ketones; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; B-Lymphocytes; Cell Survival; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Female; Humans; Indomethacin; Ketorolac; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Nitrobenzenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Salicylates; Salicylic Acid; Sulfonamides; Tolmetin; Tumor Cells, Cultured | 1998 |
Store-operated calcium influx in human gastric cells: role of endogenous prostaglandins.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Transport; Calcium; Calcium Channel Blockers; Cell Communication; Cell Line; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Lanthanum; Manganese; Nifedipine; Prostaglandin Antagonists; Thapsigargin; Verapamil | 1998 |
Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colon; Colonic Neoplasms; Diet; Glutathione Transferase; Ibuprofen; Indomethacin; Male; Nabumetone; Piroxicam; Rats; Rats, Wistar; Sulindac | 1998 |
Determination of folate transport pathways in cultured rat proximal tubule cells.
Topics: Animals; Anion Transport Proteins; Aspirin; Biological Transport; Carrier Proteins; Cells, Cultured; Folate Receptors, GPI-Anchored; Folic Acid; Glomerular Filtration Rate; Indomethacin; Kidney Tubules, Proximal; Male; Membrane Proteins; Membrane Transport Proteins; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Reduced Folate Carrier Protein; Renal Agents; Tetrahydrofolates | 1998 |
Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal antiinflammatory drugs on mucosal ulcerogenic and healing responses of the stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Hypothermia, Induced; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Nitric Oxide; Nitrobenzenes; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stomach Ulcer; Sulfonamides; Wound Healing | 1998 |
Effects of inhibitors of nitric oxide synthase on isolated uteri of fasting rats.
Topics: Animals; Aspirin; Carbon Dioxide; Carbon Radioisotopes; Fasting; Female; Glucose; Indomethacin; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Uterus | 1998 |
Systematic pharmacological approach to the characterization of NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; COS Cells; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Genetic Vectors; Humans; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Mefenamic Acid; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Time Factors; Transfection | 1998 |
Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (alphaIIbbeta3) inhibitors.
Topics: Abciximab; Animals; Antibodies, Monoclonal; Aspirin; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Disintegrins; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Indomethacin; Mice; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Recombinant Fusion Proteins | 1998 |
[Analgesic and anti-inflammatory activity of saponins of Argania spinoza].
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Indomethacin; Mice; Pain; Rats; Saponins; Trees | 1998 |
[Long-term morphofunctional preservation of guinea pig hippocampal slices following short-term treatment with cyclooxygenase inhibitors].
Topics: Animals; Aspirin; Cryopreservation; Cyclooxygenase Inhibitors; Guinea Pigs; Hippocampus; In Vitro Techniques; Indomethacin; Time Factors | 1998 |
Effect of roxatidine bismuth citrate (MX1) against acetylsalicylic acid- and indomethacin-induced gastric mucosal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Combinations; Drug Evaluation, Preclinical; Gastric Mucosa; Indomethacin; Male; Organometallic Compounds; Piperidines; Rats; Rats, Wistar; Stomach Ulcer | 1998 |
Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blotting, Northern; Blotting, Western; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, p53; Humans; Indomethacin; Protein Kinase C; Proto-Oncogene Mas; RNA, Messenger; Stomach Neoplasms; Up-Regulation | 1999 |
Involvement of prostaglandins in histamine H1 receptor-operated Ca2+ entry in human gingival fibroblasts.
Topics: Aspirin; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Chlorpheniramine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Fura-2; Gingiva; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Indomethacin; Prostaglandins; Receptors, Histamine H1; Thapsigargin | 1999 |
Evaluation of possible mechanism of anti-ulcerogenic activity of UL-409, a herbal preparation.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Carbohydrates; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Ethanol; Female; Gastric Acid; Gastric Mucins; Gastric Mucosa; In Vitro Techniques; Indomethacin; Ligation; Male; Medicine, Ayurvedic; Muscle Contraction; Muscle, Smooth; Plant Extracts; Proteins; Pylorus; Rats; Rats, Wistar | 1998 |
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Chlorocebus aethiops; Colonic Neoplasms; COS Cells; Cyclooxygenase Inhibitors; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Humans; Hypertonic Solutions; Ibuprofen; Indomethacin; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Organ Specificity; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Saline Solution, Hypertonic; Signal Transduction; Sodium Salicylate; Sorbitol; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Evidence of a cyclooxygenase-related prostaglandin synthesis in coral. The allene oxide pathway is not involved in prostaglandin biosynthesis.
Topics: Alkadienes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cnidaria; Gas Chromatography-Mass Spectrometry; Indomethacin; Leukotrienes; Magnetic Resonance Spectroscopy; ortho-Aminobenzoates; Oxides; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1999 |
The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone.
Topics: Analgesics; Animals; Aspirin; Basilar Artery; Capsaicin; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Migraine Disorders; NG-Nitroarginine Methyl Ester; Nicotine; Progesterone; Substance P; Sumatriptan; Vasodilation | 1999 |
Seizures induced by NSAID.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Male; Seizures | 1999 |
Suppressive effects of anti-inflammatory agents on human endothelial cell activation and induction of heat shock proteins.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Cells, Cultured; Chaperonin 60; Chemokine CCL2; Cyclosporine; E-Selectin; Endothelium, Vascular; Female; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Immunosuppressive Agents; Indomethacin; Intercellular Adhesion Molecule-1; Lymphocytes; Male; NF-kappa B; Transcription Factors; Vascular Cell Adhesion Molecule-1 | 1999 |
The effect of some anti-inflammatory drugs on histamine and serotonin release from rat peritoneal mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Auranofin; Diclofenac; Histamine Release; Indomethacin; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Serotonin | 1999 |
Enhancement of low density lipoprotein catabolism by non-steroidal anti-inflammatory drugs in cultured HepG2 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclosporine; Drug Interactions; Flufenamic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indomethacin; Lipoproteins, LDL; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured | 1999 |
PGHS-2 inhibitors, NS-398 and DuP-697, attenuate the inhibition of PGHS-1 by aspirin and indomethacin without altering its activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides; Thiophenes | 1999 |
Paradoxical role of PGE2 and cAMP in Actinobacillus actinomycetemcomitants strain Y4-induced lymphocyte proliferation.
Topics: Aggregatibacter actinomycetemcomitans; Animals; Aspirin; Cell Division; Culture Media, Conditioned; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Kinetics; Male; Mice; Mice, Inbred BALB C; Polymyxin B; T-Lymphocytes | 1999 |
Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus.
Topics: Animals; Aspirin; Cell Death; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Hippocampus; Indomethacin; Isoenzymes; Kainic Acid; Male; Mice; Neurons; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seizures; Sulfonamides; Time Factors | 1999 |
The photoprotective effect of ascorbic acid, acetylsalicylic acid, and indomethacin evaluated by the photo hen's egg test.
Topics: Animals; Ascorbic Acid; Aspirin; Blood Vessels; Chick Embryo; Indomethacin; Sunscreening Agents; Ultraviolet Rays; Yolk Sac | 1999 |
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2 | 1999 |
Reflex cardiovascular response to brief abdominal visceral ischemia is mediated in part by prostaglandins.
Topics: Abdomen; Animals; Aspirin; Blood Pressure; Cardiovascular Agents; Cardiovascular System; Cats; Cyclooxygenase Inhibitors; Female; Indomethacin; Ischemia; Male; Prostaglandins; Reflex; Viscera | 1999 |
Aspirin reduces apolipoprotein(a) (apo(a)) production in human hepatocytes by suppression of apo(a) gene transcription.
Topics: Apolipoproteins A; Aspirin; Gene Expression Regulation; Humans; Indomethacin; Interleukin-6; Liver; Luciferases; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Sodium Salicylate; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Synthesis of 8-epi-prostaglandin F2alpha by human endothelial cells: role of prostaglandin H2 synthase.
Topics: Animals; Aspirin; Catalase; Cell Hypoxia; Cells, Cultured; COS Cells; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelium, Vascular; Free Radical Scavengers; Humans; Hydrogen Peroxide; Indomethacin; Lipids; Mass Spectrometry; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Superoxide Dismutase; Umbilical Arteries | 1999 |
Protective effect of the nitric oxide donor molsidomine on indomethacin and aspirin-induced gastric injury in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Gastric Mucosa; Indomethacin; Molsidomine; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2000 |
Role of COX-2 inhibition on the formation and healing of gastric ulcers induced by indomethacin in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Indomethacin; Isoenzymes; Ketorolac; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Time Factors; Wound Healing | 1999 |
Intestinal tumor load in the Min/+ mouse model is not correlated with eicosanoid biosynthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Dinoprostone; Eicosanoids; Genes, APC; Indomethacin; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Sulindac | 1999 |
Prostaglandin H synthase and lipoxygenase mediated activation of xenobiotics in platelets.
Topics: Animals; Aspirin; Biotransformation; Blood Platelets; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Naphthols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Xenobiotics | 1999 |
Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Atropine; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Acid; Gastric Mucosa; Hypothermia; Indomethacin; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; Peptic Ulcer; Prostaglandins; Rats; Rats, Sprague-Dawley; Stress, Physiological; Sulfonamides; Vagotomy | 1999 |
Aspirin and some other nonsteroidal anti-inflammatory drugs inhibit cystic fibrosis transmembrane conductance regulator protein gene expression in T-84 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anions; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cell Survival; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Gene Expression Regulation; Humans; Ibuprofen; Indomethacin; Recombinant Proteins; RNA, Messenger; Thionucleotides; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1999 |
Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arteriosclerosis; Aspirin; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indans; Indomethacin; Interleukin-1; Interleukin-8; Isoenzymes; Mammary Arteries; Meloxicam; Membrane Proteins; Muscle, Smooth, Vascular; Neutrophils; Prostaglandin-Endoperoxide Synthases; Saphenous Vein; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; beta Catenin; Cell Division; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cytoskeletal Proteins; Drug Screening Assays, Antitumor; Humans; Immunoblotting; Indomethacin; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Trans-Activators; Tumor Cells, Cultured | 2000 |
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
Topics: Acetaminophen; Acetates; Analgesics; Analgesics, Non-Narcotic; Animals; Aspirin; Edema; Flavonoids; Flavonols; Formaldehyde; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Quercetin; Rats; Rats, Wistar | 2000 |
Modulation of LH/hCG receptors and physical state of ovarian membranes in rat pseudopregnancy.
Topics: Animals; Aspirin; Corpus Luteum; Cyclooxygenase Inhibitors; Female; Fluorescence Polarization; In Vitro Techniques; Indomethacin; Membrane Lipids; Membranes; Ovary; Pseudopregnancy; Rats; Rats, Wistar; Receptors, LH | 1999 |
Effects of aspirin-like drugs on nitric oxide synthesis in rat vascular smooth muscle cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; Indomethacin; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Sodium Salicylate | 2000 |
Effect of dothiepin on gastric ulceration mediated by lipid derived eicosanoids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Dothiepin; Eicosanoids; Ethanol; Indomethacin; Ligation; Male; Pylorus; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 2000 |
Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+)mice.
Topics: 6-Ketoprostaglandin F1 alpha; Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Aspirin; Body Weight; Dinoprostone; Eating; Indomethacin; Intestinal Mucosa; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Prostaglandin Antagonists | 2000 |
Involvement of cyclooxygenase 2 in the protective effect of 17beta-estradiol on hypercholesterolemic rabbit aorta.
Topics: Acetylcholine; Adenine; Animals; Aorta; Aspirin; Cholesterol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Estradiol; Hypercholesterolemia; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Triglycerides | 2000 |
The role of cyclooxygenases in endotoxin- and interleukin-1-induced hypophagia.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drinking; Endotoxins; Feeding and Eating Disorders; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lipopolysaccharides; Male; Mice; Milk; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sialoglycoproteins; Sulfonamides | 2000 |
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Cell Line; Cyclin A; Cyclin D1; Epidermal Growth Factor; Gene Expression Regulation; Genes, myc; Humans; Indomethacin; Insulin-Like Growth Factor I; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases; Salicylates; Tetradecanoylphorbol Acetate | 2000 |
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cells, Cultured; Cyclooxygenase 2; Eicosapentaenoic Acid; Endothelium, Vascular; Fatty Acids, Omega-3; Humans; In Vitro Techniques; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Microcirculation; Microsomes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Receptors, Leukotriene B4; Recombinant Proteins; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins | 2000 |
Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by upregulation of p21(Waf1) and p27(Kip1).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; DNA; Enzyme Inhibitors; Humans; Indomethacin; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Retinoblastoma Protein; Sodium Salicylate; Tumor Suppressor Proteins; Up-Regulation | 2000 |
C-reactive protein (CRP) measurement in canine serum following experimentally-induced acute gastric mucosal injury.
Topics: Animals; Aspirin; C-Reactive Protein; Dogs; Female; Gastric Mucosa; Indomethacin; Iron; Leukocyte Count; Male; Sodium Chloride | 2000 |
Protective effects of prostaglandins in the isolated gastric mucosa of the eel, Anguilla anguilla.
Topics: Alkalies; Anguilla; Animals; Aspirin; Bicarbonates; Buffers; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; HEPES; Histamine; Indomethacin; Omeprazole; Sodium | 2000 |
Collagen-affecting drugs impair regeneration of teleost tail fins.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Aspirin; Carps; Collagen; Dexamethasone; Indomethacin; Penicillamine; Regeneration; Tail; Tilapia | 2000 |
Pharmacological properties of a newly synthesized H(+)/K(+) ATPase inhibitor, 1-(2-methyl-4-methoxyphenyl)-4-.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Indomethacin; Omeprazole; Perfusion; Proton Pump Inhibitors; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach; Stomach Ulcer; Time Factors | 2001 |
Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.
Topics: Arachidonic Acid; Aspirin; Gastrointestinal Neoplasms; Genes, Reporter; Growth Substances; Humans; Indomethacin; Models, Biological; Mucins; Muscle Proteins; Neuropeptides; Peptides; Protein Kinase C; Response Elements; RNA, Messenger; Sequence Deletion; Signal Transduction; Staurosporine; Transcriptional Activation; Transfection; Trefoil Factor-2; Trefoil Factor-3; Tumor Cells, Cultured | 2001 |
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes | 2001 |
Antinociceptive properties of N-aryl-glutaramic acids and N-aryl-glutarimides.
Topics: Acetic Acid; Analgesics; Aspirin; Chromatography, Thin Layer; Formaldehyde; Glutamic Acid; Humans; Indomethacin; Magnetic Resonance Spectroscopy; Muscle Contraction; Pain; Pain Measurement; Piperidones; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2000 |
[The role of endogenous glucocorticoids in maintenance of the gastric mucosa integrity].
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Corticosterone; Gastric Mucosa; Glucocorticoids; Hormone Antagonists; Hydrocortisone; Hypothalamo-Hypophyseal System; Indomethacin; Male; Mifepristone; Peptic Ulcer Hemorrhage; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 2000 |
Role of mucus reduction and luminal acid elevation in increased susceptibility of stomach to nonsteroidal antiinflammatory drug-induced injury in arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Indomethacin; Mucus; Rats; Rats, Inbred Lew; Stomach Ulcer | 2000 |
Nitric oxide mediated effect of cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Macrophages; Mice; Nitric Oxide; Time Factors | 2001 |
Studies on the effect of diadenlyated nucleotides on calcium mobilization and prostacyclin synthesis in bovine aortic endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Calcium; Cardiovascular Agents; Cattle; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Fluorescent Dyes; Indomethacin; Nitric Oxide; Spectrometry, Fluorescence; Time Factors; Vasodilator Agents; Xanthenes | 2001 |
Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoates; Cell Death; Cell Line; Cell Nucleus; Cell Survival; Dexamethasone; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Humans; Hydrocortisone; Imidazoles; Indomethacin; Inflammation; Mefenamic Acid; Naproxen; Neuroblastoma; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Tumor Cells, Cultured | 2001 |
Effects of cyclo-oxygenase and thromboxane synthetase inhibitors on right atrial prostaglandins.
Topics: Aspirin; Benzofurans; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Heart Atria; Humans; Indomethacin; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase | 2000 |
The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Cytoskeletal Proteins; DNA, Neoplasm; Down-Regulation; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Response Elements; Signal Transduction; Subcellular Fractions; TCF Transcription Factors; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caffeine; Cell Division; Cell Line; Cyclooxygenase Inhibitors; Drug Interactions; Flow Cytometry; Indomethacin; Kidney Tubules, Collecting; Mice; Microscopy, Electron; Salicylic Acid | 2001 |
Nonsteroidal anti-inflammatory drugs impair oral mucosal repair by eliciting disturbances in endothelin-converting enzyme-1 and constitutive nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspartic Acid Endopeptidases; Aspirin; DNA Fragmentation; Endothelin-Converting Enzymes; Epithelial Cells; Indomethacin; Metalloendopeptidases; Mouth Mucosa; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oral Ulcer; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barium Sulfate; Blood Group Antigens; Contrast Media; Diclofenac; Drug Evaluation, Preclinical; Erythrocyte Indices; Female; Hemoglobins; Humans; Ibuprofen; Indicators and Reagents; Indomethacin; Leukocyte Count; Luminescent Measurements; Luminol; Male; Middle Aged; Neutrophils | 2001 |
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrins; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
COX-2 expression and cell cycle progression in human fibroblasts.
Topics: Apoptosis; Aspirin; Cell Cycle; Cells, Cultured; Culture Media, Serum-Free; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Fibroblasts; Humans; Indomethacin; Interleukin-1; Isoenzymes; Membrane Proteins; Nitrobenzenes; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Sulfonamides | 2001 |
Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase Inhibitors; Caspases; Cell Division; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Membrane Proteins; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2001 |
Thromboxane synthase regulates the migratory phenotype of human glioma cells.
Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured | 1999 |
NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gastric Mucosa; Glucosamine; Guinea Pigs; Indomethacin; Male; Microscopy, Fluorescence; Necrosis; Protein Synthesis Inhibitors; Time Factors | 2001 |
Up-regulation of gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide by aspirin but not indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Disease Models, Animal; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Indomethacin; Lipopolysaccharides; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Analgesic and antipyretic activities of Rumex patientia extract on mice and rabbits.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Aspirin; Fever; Formaldehyde; Indomethacin; Lipopolysaccharides; Male; Mice; Morphine; Pain Measurement; Plant Extracts; Plant Roots; Plants, Medicinal; Polygonaceae; Rabbits; Salmonella typhi | 2001 |
Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut.
Topics: Acute Disease; Animals; Aspirin; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Inflammation; Inflammatory Bowel Diseases; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides; Trinitrobenzenesulfonic Acid | 2001 |
Therapeutic effects of acetylsalicylic acid in giant cell arteritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dexamethasone; Drug Synergism; Giant Cell Arteritis; Glucocorticoids; Humans; Indomethacin; Interferon-gamma; Mice; Mice, SCID; Monocytes; NF-kappa B; Signal Transduction; T-Lymphocytes; Temporal Arteries; Transcription Factor AP-1; Transcription, Genetic | 2002 |
Allergenic sensitization prevents upregulation of haemopoiesis by cyclo-oxygenase inhibitors in mice.
Topics: Animals; Aspirin; Bone Marrow Cells; Cyclooxygenase Inhibitors; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Immunization; Indomethacin; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Up-Regulation | 2002 |
Effects of Opuntia ficus-indica var. Saboten stem on gastric damages in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ethanol; Ficus; Gastric Juice; Gastric Mucosa; Indomethacin; Male; Phytotherapy; Plant Extracts; Plant Stems; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2002 |
Aspirin prevents Escherichia coli lipopolysaccharide- and Staphylococcus aureus-induced downregulation of endothelial nitric oxide synthase expression in guinea pig pericardial tissue.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Down-Regulation; Drug Antagonism; Endotoxins; Escherichia coli; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pericardium; Protein Binding; RNA, Messenger; Staphylococcus aureus | 2002 |
Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Brazil; Cimetidine; Cucurbitaceae; Ethanol; Female; Flavonoids; Gastric Mucosa; Indomethacin; Male; Mice; Morphine; Motor Activity; Omeprazole; Phytotherapy; Plant Extracts; Rats; Stomach Ulcer; Tail; Toxicity Tests, Acute | 2002 |
Regulation of cyclooxygenase activity and progesterone production in the rat corpus luteum by inducible nitric oxide synthase.
Topics: Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Corpus Luteum; Cyclooxygenase Inhibitors; Depression, Chemical; Enzyme Inhibitors; Female; Gonadotropins, Equine; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; omega-N-Methylarginine; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Rats, Inbred Strains | 2002 |
Angiotensin II increases leptin secretion by 3T3-L1 and human adipocytes via a prostaglandin-independent mechanism.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Indomethacin; Kinetics; Leptin; Mice; Prostaglandins; Prostaglandins F; Time Factors | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Suppression of Japanese encephalitis virus infection by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cricetinae; Cytopathogenic Effect, Viral; Encephalitis Virus, Japanese; Indomethacin; Mice; Mitogen-Activated Protein Kinase Kinases; Neurons; Prostaglandins; Reactive Oxygen Species; Sodium Salicylate; Tumor Cells, Cultured; Virus Replication | 2002 |
Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Salicylic Acid | 2002 |
Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Chondrocytes; Diclofenac; Dose-Response Relationship, Drug; Gene Expression Regulation; Indomethacin; Interleukin-1; Meloxicam; Naproxen; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Propionates; RNA, Messenger; Thiazines; Thiazoles | 2002 |
Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Camphanes; Diclofenac; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanolamines; Indomethacin; Kinetics; Male; Mice; Mice, Inbred ICR; Pain; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Aggravation of nonsteroidal antiinflammatory drug gastropathy by glucocorticoid deficiency or blockade of glucocorticoid receptors in rats.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Corticosterone; Drug Synergism; Glucocorticoids; Hormone Antagonists; Hormone Replacement Therapy; Indomethacin; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stomach Ulcer | 2002 |
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides | 2002 |
Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma.
Topics: Animals; Aspirin; Indomethacin; Intercellular Adhesion Molecule-1; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Rats; Rats, Inbred F344; Vascular Cell Adhesion Molecule-1 | 2002 |
A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Catalysis; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; DNA, Protozoan; Gene Expression; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Molecular Sequence Data; NADPH Dehydrogenase; Naphthoquinones; Oxidation-Reduction; Prostaglandin D2; Sequence Homology, Amino Acid; Trypanocidal Agents; Trypanosoma cruzi | 2002 |
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Humans; Indomethacin; Ionophores; Isoenzymes; Leukotrienes; Lipopolysaccharides; Lipoxygenase; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2 | 2002 |
Gastroprotective effects of honey and glucose-fructose-sucrose-maltose mixture against ethanol-, indomethacin-, and acidified aspirin-induced lesions in the rat.
Topics: Animals; Aspirin; Carbohydrates; Ethanol; Female; Fructose; Glucose; Honey; Indomethacin; Male; Maltose; Peptic Ulcer Hemorrhage; Rats; Rats, Wistar; Stomach Ulcer; Sucrose | 2002 |
The combined treatment of aspirin and radiation induces apoptosis by the regulation of bcl-2 and caspase-3 in human cervical cancer cell.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 3; Caspases; Cell Division; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Gamma Rays; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, p53; HeLa Cells; Humans; Indomethacin; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Radiation-Sensitizing Agents; Sulindac; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2003 |
Impaired monocyte function in cancer patients: restoration with a cyclooxygenase-2 inhibitor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Cell Movement; Cyclooxygenase Inhibitors; Head and Neck Neoplasms; Indomethacin; Lactones; Monocytes; Prostaglandin-Endoperoxide Synthases; Receptors, CCR5; Sulfones | 2003 |
[Interaction of angiotensin converting enzyme inhibitors with nonsteroidal antiinflammatory drugs].
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Synergism; Humans; Hypertension; Indomethacin; Randomized Controlled Trials as Topic | 2002 |
[Neuroprotection by aspirin in cerebrovascular pathology].
Topics: Adenosine Triphosphate; Algorithms; Amino Acid Transport System X-AG; Animals; Aspirin; Brain Ischemia; Cell Death; Cerebrovascular Disorders; Clinical Trials as Topic; Disease Models, Animal; Glucose; Glutamic Acid; Humans; Indomethacin; Mitochondria; Neuroprotective Agents; Oxygen; Salicylates | 2002 |
Aspirin inhibits human coronary artery endothelial cell proliferation by upregulation of p53.
Topics: Arteries; Aspirin; Cell Division; Cells, Cultured; Coronary Circulation; Cyclooxygenase Inhibitors; DNA; Endothelium, Vascular; Humans; Indomethacin; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Glomerular Filtration Rate; Heart Rate; Ibuprofen; Indomethacin; Inulin; Kidney; Kidney Diseases; p-Aminohippuric Acid; Rabbits | 2002 |
Effect of amitriptyline on gastric ulceration.
Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Aspirin; Cold Temperature; Ethanol; Gastric Acid; In Vitro Techniques; Indomethacin; Male; Models, Biological; Muscarinic Antagonists; Rats; Stomach Ulcer; Stress, Psychological | 2002 |
Role of intracellular Ca2+ in endothelium-dependent contraction and relaxation of rabbit intrapulmonary arteries.
Topics: Animals; Aspirin; Calcimycin; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Ionomycin; Ionophores; Male; Methacrylates; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pulmonary Artery; Quinacrine; Rabbits; Terpenes; Thapsigargin | 2003 |
A new isoquinolinone derivative with noble vasorelaxation activity.
Topics: Acetylcholine; Adrenergic Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Atropine; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Isoquinolines; Magnetic Resonance Spectroscopy; Male; Muscarinic Antagonists; Phenylephrine; Propranolol; Pyridines; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Yohimbine | 2003 |
The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice.
Topics: Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Animals; Aspirin; Dose-Response Relationship, Drug; Female; Hot Temperature; Indomethacin; Lysine; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Pharmacogenetics; Reaction Time; Species Specificity | 2003 |
The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation.
Topics: Acid Phosphatase; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Nucleus; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Membrane Glycoproteins; Mice; Nitrobenzenes; Osteoclasts; Prostaglandin-Endoperoxide Synthases; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Stromal Cells; Sulfonamides; Tartrates; Thromboxane A2 | 2003 |
Aspirin inhibits Chlamydia pneumoniae-induced NF-kappa B activation, cyclo-oxygenase-2 expression and prostaglandin E2 synthesis and attenuates chlamydial growth.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chlamydophila pneumoniae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Bacterial; Genes, Reporter; Humans; Indomethacin; Isoenzymes; Membrane Proteins; NF-kappa B; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Tryptophan; Tumor Cells, Cultured | 2003 |
Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.
Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Hydrochloric Acid; Indomethacin; Male; Nitric Oxide; Phytotherapy; Plant Leaves; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Drug; Ruthenium Red; Sesquiterpenes; Stomach Ulcer; Sulfhydryl Compounds; Winteraceae | 2003 |
Effects of aspirin and/or salicylate on hydrolysis and glucuronidation of indomethacin in rat erythrocytes and hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzbromarone; Carboxylesterase; Chromatography, High Pressure Liquid; Drug Interactions; Erythrocytes; Glucuronides; Hepatocytes; Hydrolysis; In Vitro Techniques; Indomethacin; Male; Microsomes, Liver; Rats; Rats, Wistar; Salicylates | 2003 |
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Fibroblasts; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Middle Aged; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases | 2003 |
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac | 2003 |
Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action.
Topics: Administration, Oral; Alpinia; Animals; Aspirin; Benzyl Alcohols; Drugs, Chinese Herbal; Ethanol; Ethylmaleimide; Gastric Mucosa; Gastrointestinal Agents; Indomethacin; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Molecular Structure; NG-Nitroarginine Methyl Ester; Peptic Ulcer; Phenylpropionates; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Structure-Activity Relationship; Terpenes | 2003 |
Reduction of beta-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated beta-catenin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Binding Sites; Cell Line; Cell Line, Tumor; Cytoskeletal Proteins; Down-Regulation; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; Indomethacin; Luciferases; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Time Factors; Trans-Activators; Transcription, Genetic; Transfection | 2003 |
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway.
Topics: Animals; Aspirin; Cattle; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic N-Oxides; Cytoprotection; Diclofenac; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Imidazoles; Indomethacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine | 2003 |
Endothelial cells play an important role in the antiaggregatory effect of nitric oxide.
Topics: Adenosine Triphosphate; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Nitric Oxide; Penicillamine; Platelet Aggregation; Prospective Studies; Time Factors | 2003 |
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodenoscopy; Esophageal Diseases; Esophagoscopy; Female; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Peptic Ulcer Hemorrhage; Retrospective Studies; Stomach Ulcer | 2003 |
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Extraembryonic Membranes; Female; Furans; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Meloxicam; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles | 2003 |
Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Glioblastoma; Humans; In Situ Nick-End Labeling; Indomethacin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Heme oxygenase-1 induction may explain the antioxidant profile of aspirin.
Topics: Antioxidants; Aspirin; Bilirubin; Carbon Monoxide; Cell Line; Cell Survival; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hydrogen Peroxide; Indomethacin; Inflammation; Membrane Proteins; NG-Nitroarginine Methyl Ester; Oxidants; Umbilical Veins | 2003 |
Studies on novel 7-acyl-5-chloro-2-oxo-3H-benzoxazole derivatives as potential analgesic and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoxazoles; Capillary Permeability; Carrageenan; Drug Design; Edema; Indomethacin; Inflammation; Mice; Pain Measurement; Toxicity Tests, Acute | 2003 |
Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Disease Models, Animal; Drug Therapy, Combination; Glucosamine; Ibuprofen; Indomethacin; Ketoprofen; Mice; Pain; Piroxicam | 2003 |
Effects of aspirin and indomethacin on endothelial cell proliferation in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Humans; Indomethacin; Neovascularization, Physiologic | 2003 |
ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID.
Topics: Acetates; Adrenalectomy; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin; Dexamethasone; Edema; Granuloma; Hydrocortisone; Indoles; Indomethacin; Inflammation; Pharmacology; Phenylbutazone; Rats; Research | 1963 |
INDOMETHACIN IN RHEUMATIC DISEASES. A CONTROLLED CLINICAL TRIAL.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Indoles; Indomethacin; Peptic Ulcer Perforation; Phenylbutazone; Rheumatic Diseases; Toxicology | 1964 |
CLINICAL TEST OF INDOMETHACIN.
Topics: Analgesics; Analgesics, Non-Narcotic; Antimalarials; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Therapy; Gout; Hip Joint; Indoles; Indomethacin; Joint Diseases; Osteoarthritis; Phenylbutazone; Placebos; Prednisone; Shoulder Joint; Spondylitis; Spondylitis, Ankylosing; Toxicology | 1964 |
THE EFFECTS OF INDOMETHACIN ON RHEUMATIC FEVER.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Chorea; Drug Therapy; Indoles; Indomethacin; Rheumatic Fever; Toxicology | 1965 |
NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Flufenamic Acid; Indoles; Indomethacin; Injections, Intraperitoneal; Irritants; Mefenamic Acid; Morphine; Pain; Pharmaceutical Preparations; Pharmacology; Phenacetin; Quinones; Rats; Research; Stearic Acids | 1965 |
ANTI-INFLAMMATORY AND ANTIPYRETIC PROPERTIES OF N-(2,6-DICHLORO-M-TOLYL)ANTHRANILIC ACID (CI-583).
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin; Biological Assay; Flufenamic Acid; Granulation Tissue; Hydrocortisone; Indoles; Indomethacin; Inflammation; Mefenamic Acid; ortho-Aminobenzoates; Pharmacology; Phenylbutazone; Rats; Research | 1965 |
Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Blood Pressure; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Epoprostenol; Erythrocyte Aggregation; Hypertension; Indomethacin; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrahydroisoquinolines | 2003 |
Identification and characterization of a cyclooxygenase-like enzyme from Entamoeba histolytica.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Northern; Blotting, Southern; Catalysis; Cell Nucleus; Cloning, Molecular; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Entamoeba histolytica; Epithelial Cells; Escherichia coli; Genome; Humans; Immunoblotting; Indomethacin; Isoenzymes; Membrane Proteins; Molecular Sequence Data; Mucous Membrane; Phylogeny; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Sheep; Time Factors | 2003 |
Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility.
Topics: Alprostadil; Animals; Aspirin; Cell Membrane; Cryopreservation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Resveratrol; Semen; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes; Sulfonamides; Tolmetin; Turkeys | 2003 |
PPARgamma mediates NSAIDs-induced upregulation of TFF2 expression in gastric epithelial cells.
Topics: Anilides; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indomethacin; Mucins; Muscle Proteins; Neuropeptides; Peptides; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Trefoil Factor-2; Trefoil Factor-3; Up-Regulation | 2004 |
Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds.
Topics: Acetates; Administration, Oral; Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Hindlimb; Humans; Indomethacin; Injections, Intraperitoneal; Isoenzymes; Male; Membrane Proteins; Mice; Molecular Structure; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyridazines; Quantitative Structure-Activity Relationship | 2004 |
Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2.
Topics: Apolipoprotein A-I; Arachidonic Acid; Aspirin; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Down-Regulation; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Isoenzymes; Liver Neoplasms; Membrane Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Thromboxane B2; Transcription, Genetic | 2004 |
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose.
Topics: Actins; Angiotensin II; Animals; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; DNA, Antisense; Enzyme Inhibitors; Flavonoids; Gene Expression; Glomerular Mesangium; Glucose; Hypoglycemic Agents; Indomethacin; Ligands; Pioglitazone; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Vasoconstrictor Agents | 2004 |
Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelin-1; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mesenteric Arteries; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred WKY; Receptors, Thromboxane A2, Prostaglandin H2; Sulfonamides; Thromboxane A2; Vascular Resistance; Vasoconstriction | 2004 |
Gastric effects of the selective cyclooxygenase-2 inhibitor, celecoxib, in the rat.
Topics: Animals; Aspirin; Carrageenan; Celecoxib; Consciousness; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Indomethacin; Male; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2004 |
The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes.
Topics: Acetaminophen; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Count; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; DNA; Flurbiprofen; Furans; Humans; Indomethacin; Nitrates; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Prostaglandin-Endoperoxide Synthases | 2004 |
Gastric antisecretory and anti-ulcer effect of ME3407, a new benzimidazole derivative, in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cysteamine; Duodenal Ulcer; Epirizole; Gastric Acid; Gastric Fistula; Gastric Mucosa; Gastrins; Histamine; Immersion; Indomethacin; Male; Pepsin A; Pylorus; Pyridines; Rats; Stomach Ulcer; Thiazoles | 2004 |
Isolation of a haemorrhagic protein toxin (SA-HT) from the Indian venomous butterfish (Scatophagus argus, Linn) sting extract.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capillaries; Chromatography, Ion Exchange; Cyproheptadine; Dose-Response Relationship, Drug; Edema; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Fish Proteins; Fish Venoms; Gastrointestinal Agents; Guinea Pigs; Indomethacin; Lipoxygenase; Mice; Muscle, Smooth; Perciformes; Permeability; Rats; Spine; Superoxide Dismutase; Time Factors; Trypsin; Ultraviolet Rays; Uterus | 2004 |
Aspirin and indomethacin for the prevention of experimental port-site metastases.
Topics: Animals; Aspirin; Cell Proliferation; Indomethacin; Laparoscopy; Neoplasm Seeding; Peritoneal Neoplasms; Premedication; Punctures; Random Allocation; Rats; Rats, Inbred Dahl; Tumor Cells, Cultured | 2004 |
Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclophosphamide; Cystitis; Female; Gastric Mucosa; Indomethacin; Ketoprofen; Muscle Contraction; Muscle, Smooth; Peptic Ulcer; Prostaglandins; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2004 |
[Chronic diarrhea caused by NSAIDs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Colitis; Collagen; Colonoscopy; Diarrhea; Exocrine Pancreatic Insufficiency; Humans; Indomethacin; Male; Middle Aged; Time Factors | 2004 |
Selective inhibition of purified human phosphodiesterase 4A expressed in yeast cell GL62 by ciclamilast, piclamilast, and rolipram.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aspirin; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Indomethacin; Phosphodiesterase Inhibitors; Purinones; Pyridines; Rolipram; Saccharomyces cerevisiae | 2004 |
Inhibition of ACh-stimulated exocytosis by NSAIDs in guinea pig antral mucous cells: autocrine regulation of mucin secretion by PGE2.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Exocytosis; Guinea Pigs; Indomethacin; Male; Mucins; Vasodilator Agents | 2005 |
Dose-dependent immunomodulatory effects of acetylsalicylic acid and indomethacin in human whole blood: potential role of cyclooxygenase-2 inhibition.
Topics: Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Inflammation Mediators; Interleukin-6; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Tumor Necrosis Factor-alpha | 2004 |
Effect of aspirin and indomethacin on prostaglandin E2 synthesis in C6 glioma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Neoplasms; Dinoprostone; Dose-Response Relationship, Drug; Glioma; Humans; Immunoenzyme Techniques; Indomethacin; Time Factors; Tumor Cells, Cultured | 2004 |
Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells.
Topics: Anions; Aspirin; Cells, Cultured; Coronary Vessels; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Matrix Metalloproteinase 1; p38 Mitogen-Activated Protein Kinases; Receptors, LDL; Receptors, Oxidized LDL; Salicylates; Scavenger Receptors, Class E; Superoxides; Time Factors | 2004 |
Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Cycle; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endometrial Neoplasms; Enzyme Activation; Female; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured | 2004 |
Pharmacological and phytochemical investigations of different parts of Calophyllum brasiliense (Clusiaceae).
Topics: Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calophyllum; Chloroform; Chromatography, Thin Layer; Flowers; Formaldehyde; Fruit; Indomethacin; Methanol; Mice; Pain Measurement; Plant Extracts; Plant Roots; Solvents | 2004 |
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors | 2005 |
Protective role of heat shock protein 27 in gastric mucosal injury.
Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Drug Therapy, Combination; Epithelial Cells; Female; Gastric Mucosa; Heat-Shock Proteins; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Indomethacin; Injections, Intraperitoneal; Lactones; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfones | 2005 |
Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium Signaling; Cells, Cultured; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Exocytosis; Gastric Mucosa; Guinea Pigs; Indomethacin; Isoquinolines; Male; ortho-Aminobenzoates; Phospholipases A; Phospholipases A2; Pyloric Antrum; Sulfonamides; Time Factors | 2006 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Luciferases; Promoter Regions, Genetic; Pyrazoles; Response Elements; RNA, Messenger; RNA, Neoplasm; Sulfonamides; Telomerase; Transcription, Genetic; Tumor Cells, Cultured | 2006 |
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Indomethacin; Inflammatory Bowel Diseases; Male; Middle Aged; Nabumetone; Naproxen; Prevalence; Recurrence; Sulfonamides | 2006 |
Cytostatic and cytotoxic effects of cyclooxygenase inhibitors and their synergy with docosahexaenoic acid on the growth of human skin melanoma A-375 cells.
Topics: Antineoplastic Agents; Aspirin; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Drug Synergism; Humans; Indomethacin; Melanoma, Experimental; Piroxicam; Skin Neoplasms; Tetrazolium Salts; Thiazoles | 2005 |
Non-steroidal and steroidal anti-inflammatory drugs vary in their modulation of dendritic cell function in the elicitation phase of allergic contact dermatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betamethasone; Cell Movement; Cells, Cultured; Dendritic Cells; Dermatitis, Allergic Contact; Dinoprostone; Female; Immunohistochemistry; Indomethacin; Langerhans Cells; Lymph Nodes; Mice; Mice, Inbred BALB C; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases | 2006 |
Thromboxane mediates neutrophil superoxide production in pregnancy.
Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Indomethacin; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Pregnancy; Sulfonamides; Superoxides; Thromboxane-A Synthase; Thromboxanes | 2006 |
Synthesis of beta-hydroxypropanoic acid derivatives as potential anti-inflammatory, analgesic and antimicrobial agents.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Aspergillus; Aspirin; Bacteria; Carrageenan; Edema; Fluconazole; Hindlimb; Indomethacin; Male; Mice; Microbial Sensitivity Tests; Molecular Structure; Penicillin G; Propionates; Rats; Toxicity Tests, Acute; Ulcer | 2006 |
Oral but not parenteral aspirin upregulates COX-2 expression in rat stomachs. a relationship between COX-2 expression and PG deficiency.
Topics: Administration, Oral; Animals; Aspirin; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Motility; Gene Expression; Indomethacin; Infusions, Parenteral; Male; Prostaglandins E; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2006 |
Aspirin upregulates expression of urokinase type plasminogen activator receptor (uPAR) gene in human colon cancer cells through AP1.
Topics: Aspirin; Blotting, Western; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Cyclooxygenase 1; Humans; Indomethacin; JNK Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Transcription Factor AP-1; Up-Regulation; Urokinase-Type Plasminogen Activator | 2006 |
Towards an understanding of the structurally based potential for mechanically activated disordering of small molecule organic crystals.
Topics: Acetaminophen; Aspirin; Calorimetry, Differential Scanning; Crystallization; Indomethacin; Models, Chemical; Powders; Salicylamides; Stress, Mechanical; Sucrose; X-Ray Diffraction | 2006 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Edema; Foot; Hindlimb; Histamine; Indomethacin; Injections, Intraperitoneal; Leukocytes; Lipoxins; Male; Mice; Neutrophil Infiltration; Oligopeptides; Platelet Activating Factor; Pleurisy; Receptors, Lipoxin | 2006 |
Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1.
Topics: Acetylcholine; Animals; Arachidonic Acid; Aspirin; Calcium; Cinnamates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Guinea Pigs; Indomethacin; Ionomycin; Male; Nitrobenzenes; ortho-Aminobenzoates; Phospholipases A; Pyloric Antrum; Pyrazoles; Sulfonamides | 2006 |
Modifications produced by indomethacin and L-NAME in the effect of ultralow-dose aspirin on platelet activity in portal hypertension.
Topics: Animals; Aspirin; Blood Coagulation Tests; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Interactions; Hypertension, Portal; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activation; Platelet Function Tests; Rats; Rats, Wistar; Splanchnic Circulation; Thrombosis | 2006 |
Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Diclofenac; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Hemocyanins; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Indomethacin; Lymphocytes; Male; Maternal Exposure; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Spleen | 2007 |
Ticlopidine prevents the formation but delays the healing of ethanol-induced gastric lesions in the rat.
Topics: Administration, Oral; Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Indomethacin; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Time Factors; Wound Healing | 2007 |
Analgesic and anti-inflammatory activities of a fraction rich in gaultherin isolated from Gaultheria yunnanensis (FRANCH.) REHDER.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Croton Oil; Disaccharides; Dose-Response Relationship, Drug; Ear; Edema; Female; Formaldehyde; Gaultheria; Glycosides; Hindlimb; Indomethacin; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Rats; Rats, Wistar; Salicylates | 2007 |
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship | 2007 |
A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Aorta, Thoracic; Aspirin; Immunohistochemistry; Indomethacin; Isoproterenol; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasodilation | 2007 |
Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Central Nervous System Depressants; Dinoprostone; Disease Models, Animal; Ethanol; Flavonoids; Gastric Mucosa; Immersion; Indicators and Reagents; Indomethacin; Male; Mucus; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stomach Ulcer; Stress, Psychological; Treatment Outcome | 2007 |
Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Carrageenan; Chemical Fractionation; Cistus; Edema; Flavonoids; Hindlimb; Indomethacin; Injections; Kaempferols; Male; Mice; Molecular Structure; Plant Extracts; Plant Leaves; Quercetin; Turkey | 2007 |
Prostaglandin signaling and ovarian follicle development in the silkmoth, Bombyx mori.
Topics: Animals; Aspirin; Bombyx; Cyclic AMP; Cyclooxygenase Inhibitors; Ecdysone; Female; Homeostasis; Hydrazines; Indomethacin; Ovarian Follicle; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Signal Transduction; Vitellogenesis | 2007 |
Alkylation activity and molecular properties of two antineoplastic agents that utilise indometacin and a conjugate of aspirin with 2-aminonicotinic acid to transport nitrogen mustard groups.
Topics: Alkylation; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Aspirin; Chemical Phenomena; Chemistry, Physical; Drug Design; Hydrolysis; Indicators and Reagents; Indomethacin; Mechlorethamine; Models, Molecular; Nicotinic Acids; Skin Absorption; Software | 2007 |
Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Diclofenac; Dinoprostone; Disease Models, Animal; Guinea Pigs; Indomethacin; Male; Nasal Obstruction; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal | 2007 |
Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors.
Topics: Animals; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Design; Drug Synergism; Female; Gastric Mucosa; Humans; Hydroxamic Acids; Indomethacin; Male; Nitric Oxide Donors; Pyrazoles; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfonamides | 2007 |
Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Marrow Cells; Carrier Proteins; Cells, Cultured; Cyclooxygenase Inhibitors; Cysteine; Dinoprostone; Eosinophils; Female; Glutathione Transferase; Indomethacin; Leukotrienes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Signal Transduction | 2008 |
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, Animal; Female; Indomethacin; Inflammation; Male; Mice; Molecular Structure; Pain; Pain Measurement; Pain Threshold; Pyridines; Rats; Stomach Ulcer; Structure-Activity Relationship | 2007 |
Intracellular effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells in culture.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Size; Cells, Cultured; Diclofenac; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Indomethacin; Intracellular Membranes; Lens, Crystalline; Membrane Potential, Mitochondrial; Mitochondria; Oxidants; Oxidative Stress; Peroxides; Pyrazoles; Reactive Oxygen Species; Sulfonamides; Superoxides | 2008 |
Induction of differentiation of human leukemia cells by combinations of COX inhibitors and 1,25-dihydroxyvitamin D3 involves Raf1 but not Erk 1/2 signaling.
Topics: Aspirin; Calcitriol; Cell Differentiation; Cyclooxygenase Inhibitors; G1 Phase; HL-60 Cells; Humans; Immunoblotting; Indomethacin; Leukemia, Promyelocytic, Acute; Phosphorylation; Proto-Oncogene Proteins c-raf; RNA Interference; RNA, Small Interfering; Signal Transduction | 2008 |
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Boswellia; Ethanol; Hot Temperature; Hydrochloric Acid; Indomethacin; Leukotriene Antagonists; Ligation; Male; Phytotherapy; Rats; Rats, Wistar; Stomach Ulcer; Triterpenes | 2008 |
Hormone action and the levels of cyclic AMP and prostaglandins in the toad bladder.
Topics: Animals; Aspirin; Bufo marinus; Cyclic AMP; Indomethacin; Kinetics; Prostaglandins; Type C Phospholipases; Urinary Bladder; Vasopressins | 1972 |
Susceptibility for NSAIDs-induced apoptosis correlates to p53 gene status in gastric cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; bcl-2-Associated X Protein; Cell Line, Tumor; Dimerization; Down-Regulation; Drug Resistance, Neoplasm; Humans; Indomethacin; Mutation; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity.
Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cannabinoid Receptor Modulators; Chemistry, Pharmaceutical; Drug Design; Enzyme Inhibitors; Indomethacin; Inflammation; Kinetics; Models, Chemical; Monoacylglycerol Lipases; Rats | 2008 |
Modulation of butyrate transport in Caco-2 cells.
Topics: 2,4-Dinitrophenol; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetaldehyde; Acids, Acyclic; Aspirin; Biological Transport, Active; Butyrates; Caco-2 Cells; Caffeine; Cell Survival; Dronabinol; Gene Expression; Humans; Hydrogen-Ion Concentration; Indomethacin; Ions; Kinetics; Monocarboxylic Acid Transporters; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Azide; Symporters; Theophylline | 2009 |
Aspirin and indomethacin reduce lung inflammation of mice exposed to cigarette smoke.
Topics: Animals; Aspirin; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Indomethacin; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Nicotiana; Oxidative Stress; Pneumonia; Smoke | 2009 |
Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fetus; Gestational Age; Ibuprofen; Indomethacin; Male; Maternal Exposure; Pregnancy; Pyrazoles; Rats; Rats, Wistar | 2009 |
Synthesis and analgesic and anti-inflammatory activity of 6-phenyl/(4-methylphenyl)-3(2H)-pyridazinon-2-propionamide derivatives.
Topics: Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Carrageenan; Edema; Foot; Gastric Mucosa; Indicators and Reagents; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mice; Pain Measurement; Pyridazines; Spectrophotometry, Infrared; Stomach Ulcer | 2009 |
Anti-inflammatory drugs selectively target sporangium development in Mucor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspirin; Benzoic Acid; Ibuprofen; Indomethacin; Mitochondria; Mortierella; Mucor; Mucormycosis; Plant Diseases; Salicylic Acid | 2009 |
Synthesis and evaluation of novel 2-substituted-quinazolin-4(3H)-ones as potent analgesic and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Disease Models, Animal; Female; Indomethacin; Inflammation; Male; Mice; Pain; Pain Measurement; Quinazolines; Structure-Activity Relationship | 2010 |
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betamethasone; Brain; Brain Damage, Chronic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Encephalitis; Female; Ibotenic Acid; Indomethacin; Mice; Nerve Fibers, Myelinated; Neuroprotective Agents; Neurotoxins; Pregnancy; Pregnancy Complications; Treatment Outcome | 2010 |
Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Cholinergic Antagonists; Cimetidine; Ethanol; Flax; Gastric Mucosa; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Ileum; Indomethacin; Ligation; Linseed Oil; Misoprostol; Muscle Contraction; Promethazine; Pylorus; Rats; Rats, Wistar; Reserpine; Serotonin; Stomach Ulcer; Stress, Psychological | 2010 |
Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Exocytosis; Gastric Mucosa; Guinea Pigs; Indoles; Indomethacin; Male; PPAR alpha; Pyloric Antrum; Pyrimidines; Thapsigargin | 2010 |
Triptan therapy in migraine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Injections, Intravenous; Ketorolac; Migraine Disorders; Sumatriptan; United States; Vasoconstrictor Agents | 2010 |
A mesenchymal stromal cell line resistant to paclitaxel that spontaneously differentiates into osteoblast-like cells.
Topics: Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chondrocytes; Drug Resistance, Neoplasm; Female; Humans; Indomethacin; Mesenchymal Stem Cells; Mice; Osteoblasts; Paclitaxel; Valproic Acid | 2011 |
Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Esophagitis, Peptic; Esophagus; Gastric Acid; Humans; Indomethacin; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides | 2011 |
Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cells, Cultured; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Glucose; Humans; Indomethacin; Lactic Acid; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet-Rich Plasma | 2011 |
Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Carrageenan; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic N-Oxides; Dinoprostone; Disease Models, Animal; Edema; Female; Humans; Indomethacin; Leukotriene B4; Mice; Mice, Nude; Rats; Stomach Ulcer; Superoxide Dismutase | 2012 |
Pharmacological profile of Salvadora persica.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Behavior, Animal; Bleeding Time; Blood Coagulation; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Hand Strength; Indomethacin; Mice; Pain Measurement; Plant Extracts; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Salvadoraceae; Tranexamic Acid; Vitamin K | 2011 |
Indomethacin induces cellular morphological change and migration via epithelial-mesenchymal transition in A549 human lung cancer cells: a novel cyclooxygenase-inhibition-independent effect.
Topics: Anticarcinogenic Agents; Aspirin; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromans; Collagen Type IV; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epithelial-Mesenchymal Transition; Humans; Indomethacin; Lung Neoplasms; Matrix Metalloproteinase 9; PPAR gamma; Thiazolidinediones; Troglitazone | 2011 |
Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury.
Topics: Alkaline Phosphatase; Animals; Apoptosis; Aspirin; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cellular Microenvironment; Cobalt; Cyclooxygenase 2; Deferoxamine; Female; Fractures, Bone; Humans; Indomethacin; Mice; Osteoblasts; Poly(ADP-ribose) Polymerases; Sodium Salicylate; Sulindac | 2012 |
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays | 2012 |
Modulation of CXCR3 ligand secretion by prostaglandin E2 and cyclooxygenase inhibitors in human breast cancer.
Topics: Aspirin; Breast Neoplasms; Celecoxib; Cell Line, Tumor; Cell Survival; Chemokine CXCL10; Chemokine CXCL9; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Indomethacin; Interferon-gamma; Pyrazoles; Sulfonamides; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2012 |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.
Topics: Acetaminophen; Androgen Antagonists; Animals; Arachidonic Acid; Aspirin; Cryptorchidism; Endocrine Disruptors; Female; Indomethacin; Male; Pregnancy; Prostaglandin D2; Rats; Testis; Testosterone | 2012 |
Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caco-2 Cells; Diclofenac; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electron Transport Complex I; Humans; Ibuprofen; Indomethacin; Mitochondria; Multienzyme Complexes; NAD; Piroxicam; Protective Agents; Quercetin; Rats; Ubiquinone | 2012 |
Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dopamine Agents; Dopaminergic Neurons; Glutathione; Indomethacin; Levodopa; Meloxicam; Methyldopa; Mice; Neurons; Neuroprotective Agents; Quinones; Sympatholytics; Thiazines; Thiazoles | 2012 |
Regular ingestion of cinnamomi cortex pulveratus offers gastroprotective activity in mice.
Topics: Acrolein; Animals; Anti-Ulcer Agents; Aspirin; Cinnamomum zeylanicum; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Indomethacin; Male; Mice; Stomach Ulcer | 2013 |
Galectin-3 expression in response to LPS, immunomodulatory drugs and exogenously added galectin-3 in monocyte-like THP-1 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cytokines; Dexamethasone; Galectin 3; Gene Expression Regulation; Humans; Immunologic Factors; Indomethacin; Jurkat Cells; Lipopolysaccharides; Monocytes; Rats | 2012 |
Aspirin Induces platelet apoptosis.
Topics: Apoptosis; Aspirin; Blood Platelets; Caspase 3; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Indomethacin; Membrane Potential, Mitochondrial; Mitochondria; Phosphatidylserines; Platelet Aggregation Inhibitors; Signal Transduction; Time Factors | 2013 |
Salbutamol sulfate absorption across Calu-3 bronchial epithelia cell monolayer is inhibited in the presence of common anionic NSAIDs.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Transport; Blotting, Western; Cell Line; Drug Interactions; Epithelial Cells; Humans; Ibuprofen; Indomethacin; Respiratory Mucosa; Tight Junctions; Transendothelial and Transepithelial Migration | 2013 |
Effect of aspirin on bone healing in a rabbit ulnar osteotomy model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomechanical Phenomena; Bone Regeneration; Dose-Response Relationship, Drug; Drug Administration Schedule; Indomethacin; Observer Variation; Osteotomy; Rabbits; Radiography; ROC Curve; Single-Blind Method; Ulna; Wound Healing | 2013 |
The role of plasminogen activator inhibitor-1 in gastric mucosal protection.
Topics: Animals; Aspirin; Dinoprostone; Ethanol; Female; Gastric Mucosa; Humans; Indomethacin; Male; Mice; Plasminogen Activator Inhibitor 1; RNA, Messenger; Urokinase-Type Plasminogen Activator | 2013 |
Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes.
Topics: Adipocytes; Animals; Aspirin; Capillary Permeability; Cell Differentiation; Cells, Cultured; Chromans; Edema; Gene Expression Regulation; Guinea Pigs; Hypoglycemic Agents; Indomethacin; Male; Mice; PPAR gamma; Receptors, Retinoic Acid; Thiazolidinediones; Troglitazone; Vascular Endothelial Growth Factor A | 2013 |
Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro.
Topics: Acetaminophen; Adult; Aspirin; Cell Line; Endocrine Disruptors; Humans; Indomethacin; Inhibins; Male; Prostaglandins; Testis; Testosterone; Tissue Culture Techniques | 2013 |
Effect of NSAIDs on Na⁺/H⁺ exchanger activity in rat colonic crypts.
Topics: Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Epithelial Sodium Channel Blockers; Gene Expression Regulation; Guanidines; Humans; Hydrogen-Ion Concentration; Indomethacin; Ion Transport; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2013 |
Antioxidative effect of aspirin on vascular function of aged ovariectomized rats.
Topics: Acetylcholine; Age Factors; Animals; Antioxidants; Aorta; Aspirin; Endothelium, Vascular; Female; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Ovariectomy; Phenylephrine; Rats; Rats, Wistar | 2014 |
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides | 2013 |
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Acetaminophen; Analgesics, Non-Narcotic; Androgens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cryptorchidism; Female; Fetus; Humans; Indomethacin; Male; Organ Culture Techniques; Pregnancy; Pregnancy Trimester, First; Testis; Testosterone | 2013 |
G-protein coupled receptor-evoked glutamate exocytosis from astrocytes: role of prostaglandins.
Topics: Animals; Antibodies, Blocking; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Exocytosis; Glutamic Acid; Image Processing, Computer-Assisted; Immunohistochemistry; Indomethacin; Methoxyhydroxyphenylglycol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Transfection; Vesicular Glutamate Transport Protein 1 | 2014 |
Transdermal enhancement effect and mechanism of iontophoresis for non-steroidal anti-inflammatory drugs.
Topics: 1-Octanol; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Diffusion; Edema; Foot; Ibuprofen; In Vitro Techniques; Indomethacin; Iontophoresis; Male; Rats, Sprague-Dawley; Skin; Water | 2014 |
Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caspase 9; Cell Survival; Diclofenac; Diflunisal; Endoplasmic Reticulum Stress; Gene Expression; Glutathione; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Indomethacin; Jejunum; Male; Naproxen; Rats, Wistar; Tissue Culture Techniques | 2014 |
Cohort study of corticosteroid use and risk of hospital admission for diverticular disease.
Topics: Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Diverticulum, Colon; Female; Hospitalization; Humans; Indomethacin; Risk Factors | 2015 |
Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Aspirin; Asteraceae; Bangladesh; Edema; Female; Fever; Indomethacin; Inflammation; Male; Mice; Pain Management; Phytotherapy; Plant Extracts; Plant Leaves; Plumbaginaceae; Rats, Wistar; Time Factors; Toxicity Tests, Acute | 2014 |
Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Aspirin; Cinnamates; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Glycogen; Hep G2 Cells; Humans; Indomethacin; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Molecular Imaging; Molecular Targeted Therapy; Protein Kinases; Quantum Dots; Reproducibility of Results; Serine; Tumor Necrosis Factor-alpha | 2015 |
Evaluation of the diuretic activity in two Mexican medicinal species: Selaginella nothohybrida and Selaginella lepidophylla and its effects with ciclooxigenases inhibitors.
Topics: Animals; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Diuretics; Indomethacin; Male; Mexico; Mice; Naproxen; Plant Extracts; Plants, Medicinal; Potassium; Selaginellaceae; Sodium | 2015 |
Wheat peptides reduce oxidative stress and inhibit NO production through modulating μ-opioid receptor in a rat NSAID-induced stomach damage model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Gastric Mucosa; Gene Expression; Glutathione Peroxidase; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Plant Proteins; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; RNA, Messenger; Stomach; Superoxide Dismutase; Triticum | 2015 |
[The effect of cyclooxygenase and lipoxygenase inhibitors on Ca(2+)-responses induced by glutoxim and molixan in macrophages].
Topics: Animals; Arachidonic Acid; Aspirin; Caffeic Acids; Calcium; Calcium Signaling; Cyclooxygenase Inhibitors; Flavanones; Hematinics; Indomethacin; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Masoprocol; Oligopeptides; Primary Cell Culture; Rats; Rats, Wistar | 2014 |
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeic Acids; Eye Diseases; Indomethacin; Inflammation; Male; Phenylethyl Alcohol; Rabbits | 2015 |
Silk fibroin/copolymer composite hydrogels for the controlled and sustained release of hydrophobic/hydrophilic drugs.
Topics: Aspirin; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Fibroins; Hydrogels; Hydrophobic and Hydrophilic Interactions; Indomethacin; Polymers | 2015 |
Low miR-19b-1-5p expression in isolated platelets after aspirin use is related to aspirin insensitivity.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Blood Platelets; Coronary Artery Disease; Drug Resistance; Humans; Indomethacin; Male; MicroRNAs; Middle Aged; Platelet Aggregation Inhibitors; RNA; Simvastatin | 2016 |
Indomethacin inhibits tetrodotoxin-resistant Na(+) channels at acidic pH in rat nociceptive neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Female; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Kinetics; Male; Membrane Potentials; Naproxen; Nociceptors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Sodium Channels; Trigeminal Ganglion | 2016 |
Dual inhibition of nitric oxide and prostaglandin E2 production by polysubstituted 2-aminopyrimidines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dinoprostone; Female; Humans; Indomethacin; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrimidines; Rats, Inbred Lew; RNA, Messenger | 2016 |
Differences in Esterase Activity to Aspirin and p-Nitrophenyl Acetate among Human Serum Albumin Preparations.
Topics: Aspirin; Esterases; Humans; Hydrolysis; Indomethacin; Naproxen; Nitrophenols; Serum Albumin; Sulfhydryl Compounds; Warfarin | 2016 |
(1)H-Nuclear magnetic resonance-based metabolic profiling of nonsteroidal anti-inflammatory drug-induced adverse effects in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; Ibuprofen; Indomethacin; Least-Squares Analysis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolomics; Piroxicam; Rats; Rats, Sprague-Dawley | 2016 |
A one-pot synthesis of tetrazolones from acid chlorides: understanding functional group compatibility, and application to the late-stage functionalization of marketed drugs.
Topics: Aspirin; Azides; Benzimidazoles; Benzoates; Bexarotene; Carboxylic Acids; Chemistry Techniques, Synthetic; Chlorides; Indomethacin; Niacin; Probenecid; Silanes; Telmisartan; Tetrahydronaphthalenes; Tetrazoles | 2016 |
Inhibition of Aβ(1-42)Oligomerization, Fibrillization and Acetylcholinesterase Activity by Some Anti-Inflammatory Drugs: An in vitro Study.
Topics: Acetylcholinesterase; Amyloid; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Butylated Hydroxyanisole; Celecoxib; Dexamethasone; Diclofenac; Indomethacin; Methylene Blue; Nitric Oxide; Peptide Fragments; Piroxicam; Rivastigmine; Singlet Oxygen | 2017 |
Reduced platelet aggregation in women after intercourse: a possible role for the cyclooxygenase pathway.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Alprostadil; Aspirin; Coitus; Condoms; Female; Humans; Indomethacin; Male; Middle Aged; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Semen | 2017 |
The Effect of Ethanol on the Hydrolysis of Ester-Type Drugs by Human Serum Albumin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspirin; Binding Sites; Drug Stability; Ethanol; Excipients; Fatty Acids, Nonesterified; Humans; Hydrolysis; Indomethacin; Kinetics; Ligands; Naproxen; Nitrophenols; Olmesartan Medoxomil; Preservatives, Pharmaceutical; Serum Albumin, Human; Warfarin | 2018 |
Inhibition by non-steroidal anti-inflammatory drugs of compound action potentials in frog sciatic nerve fibers.
Topics: Action Potentials; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Naproxen; Nerve Fibers; Ranidae; Sciatic Nerve | 2018 |
Olive-Derived Hydroxytyrosol Shows Anti-inflammatory Effect without Gastric Damage in Rats.
Topics: Animals; Aspirin; Carrageenan; Celecoxib; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Indomethacin; Male; Olea; Phenylethyl Alcohol; Rats, Sprague-Dawley; Stomach; Stomach Ulcer | 2019 |
New nitric oxide-releasing indomethacin derivatives with 1,3-thiazolidine-4-one scaffold: Design, synthesis, in silico and in vitro studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Drug Design; Free Radical Scavengers; Humans; Indomethacin; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Nitric Oxide Donors; Serum Albumin, Bovine; Structure-Activity Relationship; Thiazolidines | 2021 |
Physiologically relevant aspirin concentrations trigger immunostimulatory cytokine production by human leukocytes.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cytokines; Dinoprostone; Gene Expression Regulation; Humans; Indomethacin; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Leukocytes; Male; Middle Aged; Toll-Like Receptors; Young Adult | 2021 |
Design and Synthesis In Silico Drug-like Prediction and Pharmacological Evaluation of Cyclopolymethylenic Homologous of LASSBio-1514.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Caco-2 Cells; Computer Simulation; Drug Design; Humans; Hydrazones; Hyperalgesia; Indomethacin; Male; Mice; Molecular Conformation; Molecular Weight; Pharmaceutical Preparations; Rats, Wistar | 2021 |
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2
Topics: Aged; Aged, 80 and over; Aspirin; Betamethasone; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Dietary Supplements; Early Diagnosis; Female; Flavonoids; Follow-Up Studies; Heparin, Low-Molecular-Weight; Hospitalization; Humans; Indomethacin; Italy; Male; Middle Aged; Omeprazole; Patient Acuity; Retrospective Studies; Risk Assessment; SARS-CoV-2; Time; Time-to-Treatment; Treatment Outcome | 2021 |
Biological Activity of
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line, Tumor; Cyclooxygenase 2; Endometrial Neoplasms; Female; Humans; Indomethacin; Reactive Oxygen Species; Rhenium | 2022 |
Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: Identification of a Se-indomethacin analog as a potential therapeutic for breast cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Breast Neoplasms; Female; Humans; Indomethacin; Naproxen | 2022 |