aspirin and fluorouracil

aspirin has been researched along with fluorouracil in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (16.67)	18.7374
1990's	2 (4.17)	18.2507
2000's	17 (35.42)	29.6817
2010's	16 (33.33)	24.3611
2020's	5 (10.42)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gust, R; Kircher, B; Ott, I; Schmidt, K; Schumacher, P; Wiglenda, T	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Gust, R; Huang, W; Liu, W; Qian, H; Zhang, H; Zhang, T; Zhou, J; Zhu, H	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Amin, S; Karelia, DN; Pandey, MK; Plano, D; Sharma, AK; Spallholz, JE	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C	1
Ai, Y; Lu, S; Obianom, ON	2
Ding, F; Gao, Y; Guo, Y; He, X; Li, S; Li, X; Liu, Z; Nie, Y; Wen, D; Zhang, Y; Zhong, M	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Fukuzawa, Y; Isobe, M; Kishimoto, T; Okazaki, M; Tada, M	1
Amblard, P; Bastrenta, F; Beani, JC; Gautron, R; Harrouch, L; Jardon, P; Reymond, JL	1
Rieche, K; Wand, H	1
Palasz, M	1
Slezak, H	1
Hirono, S; Ito, S	1
Capel, ID; Cosier, RS; Pinnock, MH; Williams, DC	1
Etienne, MC; Milano, G; Speziale, N	1
Bours, V; Fillet, G; Jerusalem, G	1
ROTH, JL	1
Dzik-Jurasz, AS; Leach, MO; Rowland, IJ	1
Ashktorab, H; Dawkins, FW; Larbi, D; Mohamed, R; Smoot, DT	1
Chessin, DB; Guillem, JG; Katz, MS; Minsky, BD; Riedel, E; Saltz, LB	1
Augustin, M; Cummerow, R; Hartmann, A; Schlöbe, A; Zschocke, I	1
Amadori, D; Bolla, M; Cecconetto, L; Fabbri, F; Leonetti, C; Medri, L; Rosetti, M; Scarsella, M; Tesei, A; Ulivi, P; Zoli, W; Zupi, G	1
Becker, PD; Camacho, EM; Cebolla, A; Guzmán, CA; Link, C; Royo, JL; Santero, E	1
Finlay, BB; Gal-Mor, O	1
Drew, PA; Jamieson, GG; Liu, JF; Wu, TC; Zhu, GJ	1
Chan, AP; Chan, SK; Hasan, MR; Jin, C; Kim, J; Kim, YB; Le, ND; Rahman, M; Selvarajan, K; Tai, IT	1
Jia, Q; Wang, Z; Wu, L; Zhang, W; Zhang, X; Zhang, Y	1
Ali, R; Chan, ML; Chia, WK; Deng, YH; Ho, GF; Jian, X; Mehta, S; Segelov, E; Sharma, A; Soon, SS; Tan, CS; Toh, HC; Wee, HL	1
Benson, AB; Chan, AT; Chan, JA; Fuchs, CS; Giovannucci, EL; Goldberg, RM; Hantel, A; Mayer, RJ; Meyerhardt, JA; Ng, K; Niedzwiecki, D; Ogino, S; Saltz, LB; Sato, K; Schaefer, PL; Venook, AP; Whittom, R	1
Kmieć, Z; Olejniczak-Kęder, A; Siedlecka-Kroplewska, K; Szaryńska, M; Wrońska, A	1
Fu, J; Liu, Y; Ma, L; Xu, Y; Yang, Y; Zhang, Y	1
Shen, Y; Wang, P; Zhao, L	1
Abdullahi, A; Abubakar, S; Adamu, A; Adoke, KU; Aminu, SM; Awasum, CA; Faruk, M; Ibrahim, S; Idoko, J; Iliyasu, Y; Manko, M; Mohammed, A; Musa, HS; Ntekim, A; Rafindadi, AH; Randawa, AJ; Saidu, R; Shah, KZ; Suleiman, AM	1
Dehelean, C; Ilia, I; Ionita, I; Macasoi, I; Pinzaru, I; Susan, M; Susan, R	1

Reviews

3 review(s) available for aspirin and fluorouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Effect of some drugs in the development and exacerbation of gastric and duodenal ulcer]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Jun-15, Volume: 27, Issue:12 Topics: Adrenocorticotropic Hormone; Aspirin; Caffeine; Catecholamines; Duodenal Ulcer; Fluorouracil; Glucocorticoids; Histamine; Humans; Hypoglycemic Agents; Indomethacin; Parasympathomimetics; Phenylbutazone; Quinolines; Reserpine; Stomach Ulcer	1974
[Efficacy and benefit of a 5-FU/salicylic acid preparation in the therapy of common and plantar warts--systematic literature review and meta-analysis]. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2004, Volume: 2, Issue:3 Topics: Aspirin; Drug Combinations; Fluorouracil; Foot; Humans; Internationality; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Treatment Outcome; Warts	2004

Trials

1 trial(s) available for aspirin and fluorouracil

Article	Year
A preliminary study on the postoperative survival of patients given aspirin after resection for squamous cell carcinoma of the esophagus or adenocarcinoma of the cardia. Annals of surgical oncology, 2009, Volume: 16, Issue:5 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Squamous Cell; Cardia; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Esophageal Neoplasms; Esophagectomy; Etoposide; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Radiotherapy, Adjuvant; Stomach Neoplasms; Survival Analysis	2009

Article

Year

A preliminary study on the postoperative survival of patients given aspirin after resection for squamous cell carcinoma of the esophagus or adenocarcinoma of the cardia.

Annals of surgical oncology, 2009, Volume: 16, Issue:5

Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Squamous Cell; Cardia; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Esophageal Neoplasms; Esophagectomy; Etoposide; Female; Fluorouracil; Gastrectomy; Humans; Male; Middle Aged; Radiotherapy, Adjuvant; Stomach Neoplasms; Survival Analysis

2009

Other Studies

44 other study(ies) available for aspirin and fluorouracil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Antitumor-active cobalt-alkyne complexes derived from acetylsalicylic acid: studies on the mode of drug action. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Alkynes; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell Nucleus; Cobalt; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Humans; Membrane Proteins; Organometallic Compounds; Prostaglandin-Endoperoxide Synthases	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents. Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Biological Assay; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclization; Disease Models, Animal; Drug Design; Female; Humans; Inhibitory Concentration 50; Mice; Pyrimidines; Thiourea	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents. Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship	2016
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells. European journal of medicinal chemistry, 2017, May-05, Volume: 131 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship	2017
Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer. Bioorganic & medicinal chemistry letters, 2018, 09-15, Volume: 28, Issue:17 Topics: Acrolein; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship	2018
Novel hybrids derived from aspirin and chalcones potently suppress colorectal cancer MedChemComm, 2018, Oct-01, Volume: 9, Issue:10 Topics:	2018
New organoselenides (NSAIDs-Se derivatives) as potential anticancer agents: Synthesis, biological evaluation and in silico calculations. European journal of medicinal chemistry, 2021, Jun-05, Volume: 218 Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship; Tumor Cells, Cultured	2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
[Effects of antipyretics and anticancer drug on human cells at high temperature condition]. Human cell, 1988, Volume: 1, Issue:2 Topics: Aspirin; Cells, Cultured; Dipyrone; Drug Evaluation, Preclinical; Endothelium, Vascular; Fetus; Fluorouracil; HeLa Cells; Humans; Lung; Temperature; Umbilical Veins	1988
Screening for drug photosensitization activity by measuring the variations in oxygen consumption of Bacillus subtilis. Photo-dermatology, 1985, Volume: 2, Issue:2 Topics: Aspirin; Bacillus subtilis; Benzoyl Peroxide; Chlorpromazine; Erythromycin; Fluorouracil; Light; Methoxsalen; Oxygen Consumption; Patch Tests; Photosensitivity Disorders; Tretinoin	1985
Influence of cytostatics on aggregation and adenine nucleotides of platelets. Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53 Topics: Adenine Nucleotides; Adenosine Diphosphate; Amidines; Antineoplastic Agents; Aspirin; Bleomycin; Blood Platelets; Cell Membrane; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Glyoxal; Humans; Hydrazones; Methotrexate; Neoplasms; Platelet Adhesiveness; Triaziquone; Vinca Alkaloids	1972
[Drug-induced eye lesions in the aged]. Aktuelle Gerontologie, 1983, Volume: 13, Issue:5 Topics: Aged; Antipsychotic Agents; Aspirin; Cataract; Conjunctival Diseases; Corneal Diseases; Eye Diseases; Fluorouracil; Glaucoma; Humans; Lacrimal Apparatus; Optic Nerve Diseases; Phenothiazines; Practolol; Retinal Diseases	1983
[Two cases with microangiopathic hemolytic anemia caused by anti-cancer drugs who improved rapidly after administration of aspirin and dipyridamole]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:5 Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Agents; Aspirin; Chromomycin A3; Dipyridamole; Female; Fluorouracil; Humans; Male; Mitomycin; Mitomycins; Stomach Neoplasms	1982
Use of inverted intestinal sacs to assess the effect of gastrointestinal insult on carcinogen absorption. Oncology, 1981, Volume: 38, Issue:4 Topics: Animals; Aspirin; Benzopyrenes; Carcinogens; Cold Temperature; Dimethylnitrosamine; Dose-Response Relationship, Drug; Ethanol; Fluorouracil; Intestinal Absorption; Intestinal Diseases; Male; Rats; Stress, Physiological	1981
HPLC of folinic acid diastereoisomers and 5-methyltetrahydrofolate in plasma. Clinical chemistry, 1993, Volume: 39, Issue:1 Topics: Acetaminophen; Aspirin; Chromatography, High Pressure Liquid; Fluorouracil; Humans; Leucovorin; Quality Control; Stereoisomerism; Tetrahydrofolates	1993
[How I treat colorectal cancer. I. Prevention and adjuvant treatment]. Revue medicale de Liege, 1998, Volume: 53, Issue:4 Topics: Adenocarcinoma; Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Belgium; Chemotherapy, Adjuvant; Colonic Neoplasms; Diet; Fluorouracil; Humans; Leucovorin; Levamisole; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Rate	1998
ROLE OF DRUGS IN PRODUCTION OF GASTRODUODENAL ULCER. JAMA, 1964, Feb-08, Volume: 187 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aspirin; Caffeine; Cats; Fluorouracil; Histamine; Humans; Pathology; Peptic Ulcer; Phenylbutazone; Quinolines; Research; Reserpine; Toxicology	1964
Investigation of microenvironmental factors influencing the longitudinal relaxation times of drugs and other compounds. Magnetic resonance imaging, 2004, Volume: 22, Issue:7 Topics: Albumins; Aspirin; Contrast Media; Floxacillin; Fluorocarbons; Fluorouracil; Gadolinium DTPA; Magnetic Resonance Imaging; Phantoms, Imaging; Protein Binding; Succinates; Viscosity	2004
Apoptosis induced by aspirin and 5-fluorouracil in human colonic adenocarcinoma cells. Digestive diseases and sciences, 2005, Volume: 50, Issue:6 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Aspirin; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluorouracil; Humans; Proto-Oncogene Proteins c-bcl-2	2005
Association of statin use with a pathologic complete response to neoadjuvant chemoradiation for rectal cancer. International journal of radiation oncology, biology, physics, 2005, Aug-01, Volume: 62, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Neoadjuvant Therapy; Odds Ratio; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies	2005
Efficacy of a nitric oxide-releasing nonsteroidal anti-inflammatory drug and cytotoxic drugs in human colon cancer cell lines in vitro and xenografts. Molecular cancer therapeutics, 2006, Volume: 5, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Survival; Colonic Neoplasms; Flow Cytometry; Fluorouracil; Humans; Male; Mice; Mice, Nude; Nitric Oxide; Nitro Compounds; Organoplatinum Compounds; Oxaliplatin; Transplantation, Heterologous	2006
In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit. Nature methods, 2007, Volume: 4, Issue:11 Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Animals; Aspirin; Bacterial Proteins; beta-Galactosidase; Cell Line, Tumor; Flucytosine; Fluorouracil; Gene Expression; Gene Expression Regulation, Bacterial; Genetic Engineering; Green Fluorescent Proteins; HeLa Cells; Humans; Lac Operon; Macrophages; Mice; Neoplasms; Operon; Promoter Regions, Genetic; Salmonella enterica; Salmonella Infections; Sodium Salicylate; Spleen; Transcription Factors	2007
Pathogens on aspirin: promising research and therapeutic applications. Nature methods, 2007, Volume: 4, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Proteins; Flucytosine; Fluorouracil; Gene Expression Regulation, Bacterial; Mice; Neoplasms; Salmonella enterica; Salmonella Infections; Sodium Salicylate	2007
Inhibition of COX-2 in colon cancer modulates tumor growth and MDR-1 expression to enhance tumor regression in therapy-refractory cancers in vivo. Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:7 Topics: Adult; Aged; Animals; Antineoplastic Agents; Apoptosis; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Celecoxib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Middle Aged; Pyrazoles; Sulfonamides; Xenograft Model Antitumor Assays	2012
Impact of acetylsalicylic acid on tumor angiogenesis and lymphangiogenesis through inhibition of VEGF signaling in a murine sarcoma model. Oncology reports, 2013, Volume: 29, Issue:5 Topics: Animals; Aspirin; Fluorouracil; Lymphangiogenesis; Lymphatic Vessels; Male; Mice; Neovascularization, Pathologic; Random Allocation; Sarcoma, Experimental; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C; Xenograft Model Antitumor Assays	2013
Cost-effectiveness of aspirin adjuvant therapy in early stage colorectal cancer in older patients. PloS one, 2014, Volume: 9, Issue:9 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Aspirin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Fluorouracil; Humans; Markov Chains; Models, Economic; Neoplasm Recurrence, Local; Neoplasm Staging; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Remission Induction; Reproducibility of Results; Secondary Prevention	2014
Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. Journal of the National Cancer Institute, 2015, Volume: 107, Issue:1 Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Odds Ratio; Prospective Studies; Sex Factors; Treatment Outcome	2015
Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines. International journal of oncology, 2019, Volume: 55, Issue:1 Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Autophagy; Cell Cycle; Cell Survival; Colorectal Neoplasms; Cyclooxygenase 2; ErbB Receptors; Fas Ligand Protein; fas Receptor; Fluorouracil; HCT116 Cells; HT29 Cells; Humans; Spheroids, Cellular	2019
Aspirin suppresses chemoresistance and enhances antitumor activity of 5-Fu in 5-Fu-resistant colorectal cancer by abolishing 5-Fu-induced NF-κB activation. Scientific reports, 2019, 11-15, Volume: 9, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Aspirin; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Fluorouracil; Humans; Mice; NF-kappa B; Xenograft Model Antitumor Assays	2019
Chitosan nanoparticles loaded with aspirin and 5-fluororacil enable synergistic antitumour activity through the modulation of NF-κB/COX-2 signalling pathway. IET nanobiotechnology, 2020, Volume: 14, Issue:6 Topics: Antineoplastic Agents; Aspirin; Chitosan; Cyclooxygenase 2; Drug Synergism; Fluorouracil; Hep G2 Cells; Humans; Nanoparticles; NF-kappa B; Signal Transduction	2020
Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin. PloS one, 2021, Volume: 16, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Animals; Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; B7-H1 Antigen; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; DNA Mismatch Repair; Drug Interactions; Duffy Blood-Group System; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Leucovorin; Male; Mismatch Repair Endonuclease PMS2; MutS Homolog 2 Protein; Neoplasm Proteins; Organoplatinum Compounds; Prognosis; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Cell Surface; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2021
In Vitro Assessment of the Synergistic Effect of Aspirin and 5-Fluorouracil in Colorectal Adenocarcinoma Cells. Current oncology (Toronto, Ont.), 2023, 06-27, Volume: 30, Issue:7 Topics: Adenocarcinoma; Antineoplastic Agents; Aspirin; bcl-2-Associated X Protein; Caspases; Colorectal Neoplasms; Fluorouracil; Humans	2023