aspirin and felodipine

aspirin has been researched along with felodipine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (41.38)18.2507
2000's9 (31.03)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Farr, C1
Hansson, L; Zanchetti, A2
Lim, YT; Ng, WL; Sim, EK; Yeo, TC1
Baguet, JP; Benkritly, A; Boutelant, S; Dahan, R; Mallion, JM; Noir-Clerc, M1
Kolloch, RE; Rahn, KH1
Parving, HH1
Evans, MF1
Pohl, MA; Vidt, DG1
Hansson, L1
Wesseling, H1
Benkritly, A; Hansson, L; Mallion, JM; Zanchetti, A1
Hansson, L; Jönsson, B; Stålhammar, NO1
Cao, Y; Chen, H; Tang, W; Zhang, H; Zhang, Z1

Reviews

2 review(s) available for aspirin and felodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Aggressive blood pressure lowering is safe, but benefit is still hard to prove.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Diabetes Complications; Diuretics; Drug Therapy, Combination; Felodipine; Female; Fibrinolytic Agents; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality of Life; Risk Factors

1999

Trials

11 trial(s) available for aspirin and felodipine

ArticleYear
[The Hypertension Optimal Treatment Study. Background information].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:20

    Topics: Aged; Aged, 80 and over; Aspirin; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Societies, Medical

1992
The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results.
    Blood pressure, 1994, Volume: 3, Issue:5

    Topics: Adrenergic beta-Antagonists; Age Distribution; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Asia, Eastern; Aspirin; Blood Pressure; Cardiovascular Diseases; Cholesterol; Comorbidity; Creatinine; Diabetes Mellitus; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Felodipine; Female; Humans; Hyperlipidemias; Hypertension; Israel; Lung Diseases, Obstructive; Male; Middle Aged; North America; Prospective Studies; Random Allocation; Research Design; Risk Factors; Smoking

1994
The Hypertension Optimal Treatment (HOT) Study: 24-month data on blood pressure and tolerability.
    Blood pressure, 1997, Volume: 6, Issue:5

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Morbidity; Prospective Studies; Seasons

1997
[Long-term clinical tolerance of antihypertensive treatment during the HOT study. Groupe français de l'etude HOT].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:8

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Drug Therapy, Combination; Drug Tolerance; Europe; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Male; Prospective Studies

1997
[The Hypertension Optimal Treatment (HOT) study: results of 12-month therapy related to age].
    Deutsche medizinische Wochenschrift (1946), 1998, Jan-02, Volume: 123, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Diastole; Diuretics; Felodipine; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Sodium Chloride Symporter Inhibitors; Time Factors

1998
Do intensive blood pressure lowering and low-dose ASA help our hypertensive patients?
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Diabetes Complications; Diuretics; Felodipine; Follow-Up Studies; Hemorrhage; Humans; Hypertension; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Time Factors

1998
Aggressive blood pressure lowering is safe, but benefit is still hard to prove.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Diabetes Complications; Diuretics; Drug Therapy, Combination; Felodipine; Female; Fibrinolytic Agents; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality of Life; Risk Factors

1999
The Hypertension Optimal Treatment study and the importance of lowering blood pressure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1999, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Cerebrovascular Disorders; Double-Blind Method; Drug Therapy, Combination; Felodipine; Humans; Hypertension; Middle Aged; Myocardial Infarction; Prospective Studies; Survival Rate

1999
[Lowering of diastolic blood pressure < or = 90 mmHg should not be attempted, except in type 2 diabetics; the 'Hypertension optimal treatment' (HOT) trial].
    Nederlands tijdschrift voor geneeskunde, 1999, Jun-05, Volume: 143, Issue:23

    Topics: Adult; Aged; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diastole; Felodipine; Female; Gastrointestinal Hemorrhage; Humans; Hypertension; Male; Middle Aged; Netherlands; Retrospective Studies; Survival Rate

1999
[Effect of intensive antihypertensive treatment and of aspirin in a low dose in the hypertensive. The HOT (Hypertension Optimal Treatment) study].
    Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:8

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Europe; Felodipine; Humans; Hypertension; Middle Aged

1999
Health economics in the Hypertension Optimal Treatment (HOT) study: costs and cost-effectiveness of intensive blood pressure lowering and low-dose aspirin in patients with hypertension.
    Journal of internal medicine, 2003, Volume: 253, Issue:4

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analysis; Death, Sudden, Cardiac; Diabetic Angiopathies; Drug Therapy, Combination; Felodipine; Female; Hospital Costs; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Treatment Outcome

2003

Other Studies

17 other study(ies) available for aspirin and felodipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Surgery for left main spasm. Is it indicated?
    International journal of cardiology, 1996, Volume: 54, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Vasodilator Agents

1996
Hypertension Optimal Treatment (HOT) trial.
    Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors

1998
Network-based inference methods for drug repositioning.
    Computational and mathematical methods in medicine, 2015, Volume: 2015

    Topics: Algorithms; Area Under Curve; Aspirin; Computational Biology; Computer Simulation; Databases, Factual; Drug Repositioning; Felodipine; Humans; Models, Statistical; Pharmaceutical Preparations; Predictive Value of Tests; ROC Curve; Software; Tamoxifen

2015