aspirin has been researched along with dactinomycin in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (52.78) | 18.7374 |
| 1990's | 11 (30.56) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Amlacher, E; Danz, M; Stiller, KJ; Urban, H | 1 |
| Bader, JP; Decaëns, C; Labat-Robert, J; Robert, A; Robert, L; Waldron-Edward, D | 1 |
| Brown, JM; Carmel, RJ | 1 |
| Chan, M; Metzger, MI; Mukherjee, AB; Waite, R; Yaffee, SJ | 1 |
| Bacchetti, P; Giri, SN; Rice, S | 1 |
| Chanmugam, P; Hart, S; Hwang, D; Lee, SH; Liou, S; Simmons, D; Soyoola, E; Sun, W; Zhong, H | 1 |
| Goldstone, AD; Koenig, H; Lu, CY | 1 |
| Bailey, JM; Hla, TT | 1 |
| Chakraborti, S; Gurtner, GH; Michael, JR | 1 |
| Bailey, JM | 1 |
| Bomalaski, JS; Clark, MA; Hirata, F | 1 |
| Bailey, JM; Pash, JM | 1 |
| Bartolini, G; Chiricolo, M; Fidan, M; Franceschi, C; Guerrini, F; Minghetti, L; Orlandi, M; Tomasi, V | 1 |
| Bailey, JM; Makheja, AN; Pash, J; Verma, M | 1 |
| Dietrich, M; Nawroth, PP; Stern, DM | 1 |
| Brodeur, J; Gascon, AL | 1 |
| Finkelstein, RA; Goth, A; Lexomboon, U | 1 |
| Amagaya, S; Higuchi, H; Ogihara, Y | 1 |
| Bonacossa, A; Franchi, AM; Gimeno, AL; Gimeno, MF; Seara, SM | 1 |
| Sugio, K; Takemasa, F; Tsurufuji, S; Yoshizawa, S | 1 |
| Chang, MC; Huang, TF; Wang, CY | 1 |
| Burton, M; Dieu, M; Houbion, A; Knott, I; Raes, M; Remacle, J | 1 |
| Inase, N; Lazarus, SC; Levine, TM | 1 |
| Mitchell, MD; Pollard, JK | 1 |
| Damme, B; Darmer, D; Pankow, D | 1 |
| Anges, C; Zou, M | 1 |
| Everson, WV; Johnson, RD; Nelson, DM; Polakoski, K | 1 |
| Danon, A; Rimon, G; Rosenstock, M | 1 |
| Auguet, M; Chabrier, PE; Zerrouk, A | 1 |
| Badimon, L; Martínez-González, J; Viñals, M | 1 |
| Ochmański, W | 1 |
1 review(s) available for aspirin and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for aspirin and dactinomycin
| Article | Year |
|---|---|
[Influence of antiplatelet drugs (AD) on the efectiveness of combined therapy in patients with small cell lung cancer. Part I. Influence of AD on the haemostatic system].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Blood Coagulation; Carcinoma, Small Cell; Cyclophosphamide; Dactinomycin; Humans; Lung Neoplasms; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Radiotherapy, Adjuvant; Survival Rate; Ticlopidine; Vincristine | 2008 |
34 other study(ies) available for aspirin and dactinomycin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
The proliferative activity of the adrenal cortex as influenced by carcinogenic and noncarcinogenic substances.
Topics: Adrenal Cortex; Adrenal Glands; Aflatoxins; Animals; Arsenic; Aspirin; Carcinogens; Cell Division; Dactinomycin; Morpholines; Phenols; Rats | 1975 |
The effect of drugs and secretagogues on the biosynthesis of gastric mucins.
Topics: Animals; Aspirin; Atropine; Dactinomycin; Gastric Mucins; Gastric Mucosa; Glucose; Histamine; Puromycin; Rats; Secretin; Sulfates | 1978 |
The effect of cyclophosphamide and other drugs on the incidence of pulmonary metastases in mice.
Topics: Age Factors; Animals; Antineoplastic Agents; Aspirin; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Female; Immunosuppression Therapy; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Plicamycin; Radiation Effects; Sarcoma, Experimental; Warfarin | 1977 |
Inhibition of RNA synthesis by acetyl salicylate and actinomycin D during early development in the mouse.
Topics: Animals; Aspirin; Autoradiography; Breeding; Dactinomycin; Depression, Chemical; Female; Fetal Death; Gestational Age; Infertility; Male; Mice; Oocytes; Ovary; Ovum; Placenta; Pregnancy; Reproduction; RNA; Uridine; Zygote | 1975 |
Characteristic features of actinomycin D-induced paw inflammation of the rat.
Topics: Acid Phosphatase; Animals; Aspirin; Capillary Permeability; Dactinomycin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extremities; Glucuronidase; Histamine; Hydrocortisone; Indomethacin; Inflammation; Male; Rats | 1975 |
Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide.
Topics: Animals; Aspirin; Base Sequence; Blotting, Western; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoenzymes; Kinetics; Lipopolysaccharides; Macrophages, Alveolar; Mitogens; Molecular Sequence Data; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1992 |
Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin.
Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Brain Injuries; Cold Temperature; Cycloheximide; Dactinomycin; Dexamethasone; Eflornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Differential recovery of prostacyclin synthesis in cultured vascular endothelial vs. smooth muscle cells after inactivation of cyclooxygenase with aspirin.
Topics: Animals; Aspirin; Cattle; Cells, Cultured; Chromatography, Thin Layer; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Endothelial Growth Factors; Endothelium, Vascular; Epidermal Growth Factor; Epoprostenol; Gene Expression Regulation; Growth Substances; Humans; Muscle, Smooth, Vascular; Rats; Thymidine | 1989 |
Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Kinetics; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Pulmonary Artery; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1989 |
Regulation of cyclooxygenase synthesis by EGF and corticosteroids.
Topics: Animals; Aspirin; Cell Membrane; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Epidermal Growth Factor; Muscle, Smooth; Prostaglandin-Endoperoxide Synthases; Rats; Transforming Growth Factors | 1989 |
Aspirin inhibits phospholipase C.
Topics: Annexins; Aspirin; Cycloheximide; Dactinomycin; Glycoproteins; Humans; Indomethacin; Salicylates; Type C Phospholipases | 1986 |
Inhibition by corticosteroids of epidermal growth factor-induced recovery of cyclooxygenase after aspirin inactivation.
Topics: Adrenal Cortex Hormones; Animals; Annexins; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cells, Cultured; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Enzyme Activation; Epidermal Growth Factor; Epoprostenol; Glycoproteins; Kinetics; Male; Muscle, Smooth, Vascular; Peptides; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Transforming Growth Factors | 1988 |
Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system.
Topics: ABO Blood-Group System; Animals; Aspirin; Blood; Cattle; Dactinomycin; Dinoprostone; Enzyme Induction; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Monocytes; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Thromboxane A2; Thromboxane B2 | 1986 |
Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells.
Topics: Adrenal Cortex Hormones; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cortisone; Cycloheximide; Dactinomycin; Dexamethasone; DNA Probes; Drug Synergism; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains; RNA, Messenger; Transforming Growth Factors | 1988 |
Thromboxane production by perturbed bovine aortic endothelial cells in culture.
Topics: Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Endothelium; Endotoxins; Imidazoles; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
Influence of microsomal enzyme inducers on the reactivity of the isolated guinea pig seminal vesicle to angiotensin and tyramine.
Topics: Angiotensin II; Animals; Aspirin; Dactinomycin; DDT; Drug Antagonism; Enzyme Induction; Glutethimide; Guinea Pigs; Male; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Piperazines; Proadifen; Protein Biosynthesis; Seminal Vesicles; Sulfanilamides; Tyramine | 1969 |
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone | 1971 |
Blockade by anti-glucocorticoids, actinomycin D and cycloheximide of the anti-inflammatory action of some Kampohozai (Chinese traditional medicines) against serotonin.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cycloheximide; Dactinomycin; Dexamethasone; Drugs, Chinese Herbal; Glucocorticoids; Indomethacin; Inflammation; Magnoliopsida; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Methyltestosterone; Mice; Phenylbutazone; Phytotherapy; Progesterone; Serotonin; Serotonin Antagonists; Time Factors | 1984 |
Effects of cycloheximide, puromycin and actinomycin D on the spontaneous motility of isolated rat uterus.
Topics: Animals; Aspirin; Castration; Cycloheximide; Dactinomycin; Drug Interactions; Female; In Vitro Techniques; Prostaglandins; Puromycin; Rats; Rats, Inbred Strains; Time Factors; Uterine Contraction | 1982 |
Blockade by antiglucocorticoids, actinomycin D and cycloheximide of anti-inflammatory action of dexamethasone against bradykinin.
Topics: Androstenedione; Animals; Aspirin; Bradykinin; Cell Membrane Permeability; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Edema; Glucocorticoids; Inflammation; Male; Methyltestosterone; Mice; Phenylbutazone; Progesterone; Prostaglandins; Protein Biosynthesis; RNA; Time Factors | 1980 |
Ancrod-formed fibrin stimulates prostacyclin production of human umbilical vein endothelial cells via de novo synthesis of cyclooxygenase.
Topics: 6-Ketoprostaglandin F1 alpha; Ancrod; Aspirin; Blotting, Western; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Epoprostenol; Fibrin; Humans; Kinetics; Oligopeptides; Prostaglandin-Endoperoxide Synthases; Umbilical Veins | 1994 |
Induction of cyclooxygenase by interleukin 1: comparative study between human synovial cells and chondrocytes.
Topics: Arachidonic Acid; Aspirin; Cartilage; Cells, Cultured; Cyclophosphamide; Dactinomycin; Dinoprostone; Enzyme Induction; Humans; Interleukin-1; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Biosynthesis; Recombinant Proteins; Synovial Membrane; Transcription, Genetic | 1994 |
Mitogen-inducible prostaglandin G/H synthase is expressed in canine mastocytoma cells.
Topics: Animals; Aspirin; Cycloheximide; Dactinomycin; Dexamethasone; Dogs; Gene Expression; Mast Cells; Mast-Cell Sarcoma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Induction of hepatic cytochrome P4502E1 in rats by acetylsalicylic acid or sodium salicylate.
Topics: Animals; Aspirin; Blotting, Northern; Cycloheximide; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Oxidoreductases, N-Demethylating; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Sodium Salicylate; Transcriptional Activation | 1996 |
Cell-cell interaction between platelets and IL-1 beta-stimulated vascular smooth muscle cells in synthesis of thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Communication; Cells, Cultured; Coculture Techniques; Cycloheximide; Dactinomycin; Humans; Interleukin-1; Muscle, Smooth, Vascular; Phospholipids; Prostaglandin Endoperoxides; Prostaglandin H2; Prostaglandins H; Rats; Recombinant Proteins; Thrombin; Thromboxane A2 | 1997 |
Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxyeicosatetraenoic Acids; Isomerism; Platelet Aggregation Inhibitors; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; Radioimmunoassay; Thromboxane B2; Time Factors; Trophoblasts | 1997 |
Prostaglandin H synthase: protein synthesis-independent regulation in bovine aortic endothelial cells.
Topics: Aluminum Compounds; Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fluorides; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoenzymes; Kinetics; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Sodium Fluoride; Sulfonamides; Time Factors; Vanadates | 1997 |
Augmented endothelium-dependent contraction to angiotensin II in the SHR aorta: role of an inducible cyclooxygenase metabolite.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Time Factors; Vasoconstrictor Agents | 1998 |
Regulatory effects of HDL on smooth muscle cell prostacyclin release.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aspirin; Cells, Cultured; Cholesterol, HDL; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dactinomycin; Dexamethasone; Enzyme Inhibitors; Epoprostenol; Flavonoids; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Synthesis Inhibitors; Rabbits; RNA, Messenger | 1999 |