aspirin has been researched along with cyclin d1 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 11 (45.83) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Beauchamp, RD; DuBois, RN; Shao, J; Sheng, H; Tsujii, M | 1 |
| Aakre, ME; Chytil, A; Entingh, AJ; Law, BK; Moses, HL; Nørgaard, P; Waltner-Law, ME | 1 |
| Dihlmann, S; Siermann, A; von Knebel Doeberitz, M | 1 |
| Espiritu, I; Pinkerton, KE; Suffia, M; Witschi, H | 1 |
| Gao, J; Liu, X; Rigas, B | 1 |
| Chen, X; Cong, X; Hu, S; Wang, Y; Zhang, H; Zhu, W | 1 |
| Dunlop, MG; Stark, LA; Thoms, HC | 1 |
| Hu, L; Shi, J; Wang, L | 1 |
| Huang, L; Rigas, B; Sun, Y; Zhou, H | 1 |
| Hu, H; Zhang, S; Zhu, S | 1 |
| Chattopadhyay, M; Kashfi, K; Kogan, M; Nath, N; Vassell, R | 1 |
| Hua, A; Mackenzie, GG; Rigas, B | 1 |
| He, SM; Huang, YJ; Leng, TD; Li, Y; Ou, YQ; Qiu, PX; Xie, J; Xu, D; Yan, GM; Zheng, XK; Zhu, Wb | 1 |
| Benamouzig, R; Chaussade, S; Deyra, J; Girard, B; Little, J; Martin, A; Uzzan, B | 1 |
| Boardman, LA; Greenspan, EJ; Madigan, JP; Rosenberg, DW | 1 |
| Janakiram, NB; Li, Q; Lightfoot, S; Mohammed, A; Rao, CV; Ritchie, RL; Steele, VE; Vibhudutta, A | 1 |
| Cheng, BQ; Jiang, Y; Lin, WG; Zhu, Q | 1 |
| Carpizo, D; DiPaola, RS; Huang, H; Lin, Y; Tan, XL; Xu, Q; Yang, CS; Yue, W; Zheng, X | 1 |
| Bai, YH; Fan, DD; Li, L; Li, S; Lin, S; Ma, XL; Qiu, WH; Song, YP; Wang, ZY; Zong, M | 1 |
| Cheng, R; Cui, JW; Fang, ZY; Li, P; Li, YX; Liu, XL; Liu, YJ; Lu, SY; Wang, Z; Wei, W; Wu, XQ; Yang, M; Zhou, Y; Zhu, LZ; Zou, L | 1 |
| Cai, JR; Gao, M; Guo, KM; Ma, MM; Wei, YM; Xia, TT; Ye, QJ | 1 |
| Bashir, AIJ; Jones, S; Kankipati, CS; Newman, RM; Nicholl, ID; Perry, CJ; Safrany, ST | 1 |
| Fujita, K; Gong, J; Iwama, H; Kobara, H; Liu, S; Masaki, T; Morishita, A; Nakahara, M; Nishiyama, N; Nonura, T; Okano, K; Shi, T; Suzuki, Y; Yoneyama, H | 1 |
| Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X | 1 |
1 trial(s) available for aspirin and cyclin d1
| Article | Year |
|---|---|
Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention.
Topics: Adenoma; Adolescent; Adult; Aged; Anticarcinogenic Agents; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Genes, ras; Humans; Male; Middle Aged; Mutation; Neoplasm Proteins; Neoplasm Recurrence, Local; Tumor Suppressor Protein p53; Young Adult | 2010 |
23 other study(ies) available for aspirin and cyclin d1
| Article | Year |
|---|---|
G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.
Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cell Line; Colonic Neoplasms; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; DNA; Epithelium; G1 Phase; Humans; Intestines; Kinetics; Oncogene Proteins; Open Reading Frames; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Rats; Recombinant Proteins; Retinoblastoma Protein; Time Factors; Transfection; United States | 1996 |
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Cell Line; Cyclin A; Cyclin D1; Epidermal Growth Factor; Gene Expression Regulation; Genes, myc; Humans; Indomethacin; Insulin-Like Growth Factor I; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases; Salicylates; Tetradecanoylphorbol Acetate | 2000 |
The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Cytoskeletal Proteins; DNA, Neoplasm; Down-Regulation; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Response Elements; Signal Transduction; Subcellular Fractions; TCF Transcription Factors; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Aspirin; Blotting, Western; Cell Nucleus; Cyclin D1; Cyclin D2; Cyclins; Cyclohexenes; Dexamethasone; Free Radical Scavengers; Immunohistochemistry; Inositol; Isothiocyanates; Limonene; Lung; Lung Neoplasms; Male; Mice; Nicotiana; Organoselenium Compounds; Tea; Terpenes; Time Factors | 2002 |
Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress.
Topics: Adenocarcinoma; Adherens Junctions; Animals; Antineoplastic Agents; Apoptosis; Aspirin; beta Catenin; Caspase 3; Caspases; Cell Line, Tumor; Colonic Neoplasms; Cyclin D1; Down-Regulation; Genes, APC; Humans; Hydrolysis; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Oxidative Stress; Signal Transduction | 2005 |
Growth inhibition of mesenchymal stem cells by aspirin: involvement of the WNT/beta-catenin signal pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclin D1; Dose-Response Relationship, Drug; Mesenchymal Stem Cells; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Wnt Proteins | 2006 |
p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells.
Topics: Apoptosis; Aspirin; Cell Cycle; Cell Nucleolus; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Enzyme Activation; HT29 Cells; Humans; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Transcription Factor RelA | 2007 |
Down-regulation of beta-catenin nuclear localization by aspirin correlates with growth inhibition of Jurkat cell line.
Topics: Aspirin; beta Catenin; Cell Cycle; Cell Cycle Checkpoints; Cell Nucleus; Cell Proliferation; Cyclin D1; Down-Regulation; Humans; Jurkat Cells | 2006 |
Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Inhibitory Concentration 50; Necrosis; Nitric Oxide; Oxidation-Reduction; Pancreatic Neoplasms; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2009 |
Influence of aspirin and cigarette smoke extract on the expression of cyclin D1 and effects of cell cycle in esophageal squamous cell carcinoma cell line.
Topics: Analysis of Variance; Aspirin; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclin D1; Esophageal Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Nicotiana; Probability; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Smoke | 2009 |
Nitro-aspirin inhibits MCF-7 breast cancer cell growth: effects on COX-2 expression and Wnt/beta-catenin/TCF-4 signaling.
Topics: Anticarcinogenic Agents; Aspirin; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclooxygenase 2; DNA-Binding Proteins; Down-Regulation; Enzyme Induction; Female; Genes, Reporter; Humans; Inhibitory Concentration 50; Isomerism; Signal Transduction; Transcription Factor 4; Transcription Factors; Transcription, Genetic; Wnt Proteins | 2009 |
The differential cell signaling effects of two positional isomers of the anticancer NO-donating aspirin.
Topics: Activating Transcription Factor 2; Antineoplastic Agents; Aspirin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Activation; HT29 Cells; Humans; Inhibitory Concentration 50; Isomerism; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-jun; RNA Interference; Signal Transduction; Structure-Activity Relationship; Time Factors; Transcription Factor AP-1 | 2009 |
Aspirin inhibits proliferation of gemcitabine-resistant human pancreatic cancer cells and augments gemcitabine-induced cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Aspirin; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Deoxycytidine; Drug Synergism; Flow Cytometry; Gemcitabine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2 | 2010 |
Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}.
Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Blotting, Western; Cell Nucleus; Colonic Neoplasms; Cyclin D1; Female; Fluorescent Antibody Technique; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Ibuprofen; Immunoenzyme Techniques; Male; Middle Aged; NF-kappa B; Phosphorylation; Signal Transduction; Tumor Cells, Cultured; Wnt Proteins | 2011 |
Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
Topics: Animals; Anticarcinogenic Agents; Aspirin; beta Catenin; Body Weight; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Progression; Humans; Integrases; Male; Mice; Mice, Transgenic; Nitric Oxide Synthase Type II; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins p21(ras); Tumor Suppressor Protein p53 | 2012 |
Wnt/β-catenin aids in regulating the proliferation of hepG2 cells mediated by thy-1.
Topics: Apoptosis; Aspirin; beta Catenin; Cell Proliferation; Cyclin D1; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Thy-1 Antigens; Transgenes; Wnt Signaling Pathway | 2014 |
Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Aspirin; Bcl-2-Like Protein 11; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclin D1; Female; Humans; Membrane Proteins; Metformin; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Wound Healing | 2015 |
Anti-cancer activity and potential mechanism of a novel aspirin derivative.
Topics: Antineoplastic Agents; Apoptosis; Aspirin; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Humans; NF-kappa B; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation | 2016 |
Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Aspirin; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hydroxytestosterones; Proto-Oncogene Proteins c-myc; Receptors, Estrogen; Tamoxifen | 2017 |
Aspirin inhibits the proliferation of human uterine leiomyoma cells by downregulation of K‑Ras‑p110α interaction.
Topics: Apoptosis; Aspirin; Caspases; Cell Cycle Checkpoints; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Cyclin D1; Cyclin-Dependent Kinase 2; Flow Cytometry; Humans; Leiomyoma; Proto-Oncogene Proteins p21(ras); Signal Transduction | 2017 |
A novel mechanism for the anticancer activity of aspirin and salicylates.
Topics: Aspirin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclin D1; Drug Screening Assays, Antitumor; EGF Family of Proteins; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Phosphorylation; Salicylates; Signal Transduction | 2019 |
Aspirin inhibits cholangiocarcinoma cell proliferation via cell cycle arrest in vitro and in vivo.
Topics: Animals; Apoptosis; Aspirin; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Computational Biology; Cyclin D1; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Xenograft Model Antitumor Assays | 2021 |
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor | 2022 |