aspirin and cyclic gmp

aspirin has been researched along with cyclic gmp in 87 studies

Research

Studies (87)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (35.63)	18.7374
1990's	25 (28.74)	18.2507
2000's	24 (27.59)	29.6817
2010's	7 (8.05)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Riding, GV	1
Kaliner, M	1
Kaliner, M; Platshon, LF	1
Austen, KF; Goetzl, EJ; Pickett, WC	1
Silver, MJ; Smith, JB	1
Haslam, RJ	1
Farris, RK; Morris, SM; Powell, DW; Tapper, EJ	1
Yasunaga, K	1
George, DT; Mapes, CA; Sobocinski, PZ	1
Carr, DW; Gerrard, JM; Glass, DB; Goldberg, ND; Townsend, D; White, JG	1
Dekanski, JB; Gottfried, S; Macdonald, A; Parke, DV; Sacra, P	1
Austen, KF; Goetzl, EJ; Pickett, W; Schoepflin, GS	1
Austen, KF; Goetzl, EJ; Schoepflin, GS	1
Castania, A; Rothschild, AM	1
Krzanowski, JJ; Polson, JB; Szentivanyi, A	1
Waitzman, MB	1
Chiang, TM	1
Moncada, S; Palmer, RM; Radomski, MW	1
Bruckdorfer, KR; Dunn, RC; Feher, MD; Miles, CM; Schachter, M; Sever, PS; Tranter, PR	1
Armstrong, RA; Jones, RL; Wilson, NH	1
Axelsson, KL; Bornfeldt, KE	1
Manganiello, VC; Stoner, J; Vaughan, M	1
Haslam, RJ; McClenaghan, MD	1
Goetter, WE	1
Best, LC; Bone, EA; Holland, TK; Hunt, NH; Jones, PB	1
Davis, BB; Rapp, NS; Zenser, TV	1
Kolb, JP; Rochette-Egly, C; Tovey, MG	1
Salzman, EW; Steer, ML	1
Cornelius, LM; Evatt, BL; Waitzman, MB	1
Cagen, LM; Chiang, TM; Kang, AH	1
Kazmi, GM; Littner, MR; Lott, FD	1
DeCampli, WM; Obayashi, DY; Wanna, FS; Young, JN	1
Gulati, A; Sharma, AC; Singh, G	1
Folts, JD; Loscalzo, J; Rovin, JD; Stamler, JS	1
Gear, AR; Polanowska-Grabowska, R	1
Hsu, P; Leffler, CW; Parfenova, H	1
Ashikaga, T; Hata, A; Kishi, Y; Makita, T; Numano, F; Watanabe, R	1
Freas, W; Hart, J; Jing, M; Llave, R; McQuillan, P; Muldoon, S	1
Abendschein, DR; Meng, YY; Ryan, US; Trachtenburg, J	1
Guandalini, S; Iafusco, M; Nocerino, A	1
Alberola, ML; Caramelo, C; Casado, S; Esteban, A; López-Farré, A; Millás, I; Montón, M	1
Grünberg, B; Kratzer, MA; Lorenz, R; Negrescu, EV; Siess, W	1
Alexandre, A; Borean, A; Cavallini, L; Coassin, M	1
Albert, J; Bröijersén, A; Frostell, C; Hjemdahl, P; Wallén, NH	1
Eigler, NL; Forrester, JS; Hutsell, TC; Kaul, S; Litvack, FI; Makkar, RR; Nakamura, M; Shah, PK	1
Clambey, ET; Katusić, ZS; Lee, HC	1
Bina, S; Jing, M; Ledvina, MA; Muldoon, SM; Panico, FG; Panico, JL	1
Andrioli, G; Bellavite, P; Benoni, G; Degan, M; Gaino, S; Lechi, A; Lechi, C; Minuz, P; Ortolani, R; Tommasoli, R; Zuliani, V	1
Gulati, A; Sen, AP; Sharma, AC; Singh, G	1
Sang, JC; Schachter, D	1
Chen, L; Mehta, JL; Salafranca, MN	1
Bernasconi, S; Dejana, E; Del Maschio, A; Martín-Padura, I	1
Bellver, T; Casado, S; Esteban, A; Farré, J; García-Durán, M; Guerra, JI; López-Farré, A; Mata, P; Montón, M; Rico, LA; Romero, J; Sánchez de Miguel, L; Sierra, MP	1
Cecchi, E; Failli, P; Giotti, A; Laffi, G; Mugelli, A; Tosti-Guerra, C; Zilletti, L	1
Frölich, JC; Ikic, M; Raida, M; Tewes, KS; Tsikas, D	1
Antonelli, E; Del Soldato, P; Federici, B; Fiorucci, S; Mannucci, R; Miglietti, M; Morelli, A; Morelli, O; Santucci, L	1
Nakaki, T	1
Blanco, E; De La Cruz, JP; Sánchez de la Cuesta, F	1
Grosser, N; Schröder, H	2
Bernareggi, M; Berti, F; Colonna, VD; Manfredi, B; Rossoni, G	1
Degan, M; Gaino, S; Lechi, A; Meneguzzi, A; Minuz, P; Santonastaso, CL; Soldato, PD; Zuliani, V	1
Monobe, H; Nakamura, K; Ohe, T; Yamanari, H	1
Hong, E; Huang, F; Sun, J; Xiu, Q	1
Arriero, MM; Casado, S; Celdran, A; de la Pinta, JC; Escribano, M; García-Mendez, A; Jimenez, P; López-Farré, A; Manzarbeitia, F; Muñoz-Alameda, L; Reyero, A	1
Fiorucci, S; Ignarro, LJ; Wallace, JL	1
Berti, F; Del Soldato, P; Manfredi, B; Rossoni, G	1
Angelini, GD; Ascione, R; Capoun, R; Jeremy, JY; Shukla, N; Talpahewa, S	1
Berti, F; Del Soldato, P; Manfredi, B; Polvani, G; Rossoni, G	1
Chen, J; Gao, J; Hundley, TR; Kashfi, K; Kopelovich, L; Nath, N; Rigas, B; Williams, JL	1
Donati, S; Filippi, S; Forti, G; Lotti, F; Maggi, M; Mancina, R; Marini, M; Mondaini, N; Montorsi, F; Morelli, A; Salonia, A; Vannelli, GB; Vignozzi, L	1
Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P	1
Cockcroft, JR; Coffey, MJ; Coles, B; Lewis, MJ; Morrow, JD; O'Donnell, VB; Sanchez, S; Williams, PC	1
Bode-Böger, SM; Martens-Lobenhoffer, J; Scalera, F; Schröder, H; Täger, M	1
Abraham, R; Biaggioni, I; Diedrich, A; Farley, G; Gamboa, A; Paranjape, SY; Shibao, C	1
Bhattacharya, G; Girish, GV; Sinha, AK	1
Clough, GF; Gooding, KM; Hannemann, MM; Shore, AC; Tooke, JE	1
Andersson, J; Bengtsson, T; Grenegård, M; Kälvegren, H	1
Bhattacharya, G; Bhattacharya, R; Bhattacharyya, M; Karmohapatra, SK; Sinha, AK	1
Ferro, A; Jackson, G; Ji, Y; Liu, Z; O'Kane, P; Queen, L; Xie, L	1
Handa, M; Ikeda, Y; Okamura, Y; Watanabe, N; Yoshida, H	1
Bhatia, S; Medhi, B; Parmar, VS; Prasad, AK; Priya, N; Raj, HG; Singh, P	1
Anfossi, G; Barale, C; Cavalot, F; Doronzo, G; Mattiello, L; Pagliarino, A; Russo, I; Trovati, M; Viretto, M	1
Capogrossi, M; Gaetani, E; Gatto, I; Giarretta, I; Hlatky, L; Landolfi, R; Marcantoni, M; Neri, V; Palladino, M; Pola, R; Silver, M; Smith, RC; Stigliano, E; Straino, S	1
Hamzah, AS; Kek, TL; Mansor, NS; Mohammat, MF; Salleh, MZ; Sani, MH; Shaameri, Z; Zakaria, ZA	1
Gambaryan, S; Geiger, J; Kharazova, A; Panteleev, M; Rukoyatkina, N; Shpakova, V	1
Huang, MZ; Jiao, ZH; Kong, XJ; Li, JY; Li, SH; Liu, XW; Ma, N; Qin, Z; Shen, DS; Yang, YJ	1

Reviews

7 review(s) available for aspirin and cyclic gmp

Article	Year
[Lysosomes, cyclic nucleotides and retinal degeneration]. Vestnik Akademii meditsinskikh nauk SSSR, 1978, Issue:10 Topics: Animals; Aspirin; Cortisone; Cyclic AMP; Cyclic GMP; Darkness; DNA; Lysosomes; Mice; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Retina; Retinal Degeneration; Salicylates; Species Specificity	1978
[Present status and prospects of platelet inhibitors]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1976, Volume: 17, Issue:6 Topics: Adenosine; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Combinations; Drug Synergism; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandins E; Serotonin; Theophylline; Thrombosis	1976
Proposed metabolic dysfunctions in diabetic microthromboses and microangiopathy. Metabolism: clinical and experimental, 1979, Volume: 28, Issue:4 Suppl 1 Topics: Alprostadil; Aspirin; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dinoprost; Dinoprostone; Humans; Indomethacin; Models, Biological; Platelet Aggregation; Prostaglandins; Prostaglandins E; Prostaglandins F; Thromboxane A2	1979
The pathophysiology of asthma. Extrinsic influences other than immunologic. Clinics in chest medicine, 1984, Volume: 5, Issue:4 Topics: Aerosols; Air Pollution; Aspirin; Asthma; Asthma, Exercise-Induced; Autonomic Nervous System; Cyclic AMP; Cyclic GMP; Emotions; Humans; Humidity; Immunoglobulin E; Occupational Diseases; Parasympathetic Nervous System; Receptors, Adrenergic; Respiratory Tract Infections; Tobacco Smoke Pollution	1984
Cyclic nucleotides in hemostasis and thrombosis. Advances in cyclic nucleotide research, 1980, Volume: 12 Topics: Aspirin; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diet; Hemostasis; Humans; Male; Phosphorylation; Platelet Aggregation; Prostaglandins; Protein Kinases; Proteins; Thrombosis; Thromboxanes	1980
[Nitic oxide and natriuretic peptides]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Adenylyl Cyclase Inhibitors; Aspirin; Cyclic GMP; Drug Design; Humans; Natriuretic Agents; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfhydryl Compounds; Sulfones	2000
Potential cardioprotective actions of no-releasing aspirin. Nature reviews. Drug discovery, 2002, Volume: 1, Issue:5 Topics: Animals; Apoptosis; Arteriosclerosis; Aspirin; Caspase Inhibitors; Cell Adhesion; Cyclic GMP; Cytokines; Heart; Humans; Hypertension; Myocardial Infarction; Stroke	2002

Trials

4 trial(s) available for aspirin and cyclic gmp

Article	Year
Effects of inhaled nitric oxide compared with aspirin on platelet function in vivo in healthy subjects. Clinical science (London, England : 1979), 1996, Volume: 91, Issue:2 Topics: Administration, Inhalation; Administration, Oral; Aspirin; Bleeding Time; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Nitric Oxide; Platelet Aggregation	1996
In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood, 2005, Oct-15, Volume: 106, Issue:8 Topics: Aspirin; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Health; Humans; Isoenzymes; Nitric Oxide; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxanes; Time Factors	2005
Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole. Stroke, 2005, Volume: 36, Issue:10 Topics: Acetylcholine; Adenosine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Flow Velocity; Cardiovascular System; Cross-Over Studies; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Models, Biological; Nitric Oxide; Nitroprusside; Phosphoric Diester Hydrolases; Time Factors; Vasodilator Agents	2005
Maximum skin hyperaemia induced by local heating: possible mechanisms. Journal of vascular research, 2006, Volume: 43, Issue:3 Topics: Aspirin; Cetirizine; Cross-Over Studies; Cyclic GMP; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans; Hyperemia; Laser-Doppler Flowmetry; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Piperazines; Prostaglandins; Purines; Reference Values; Regional Blood Flow; Sildenafil Citrate; Skin; Sulfones; Ultrasonography	2006

Other Studies

76 other study(ies) available for aspirin and cyclic gmp

Article	Year
Human lung tissue and anaphylaxis. I. The role of cyclic GMP as a modulator of the immunologically induced secretory process. The Journal of allergy and clinical immunology, 1977, Volume: 60, Issue:3 Topics: Acetylcholine; Anaphylaxis; Antigens; Aspirin; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Histamine Release; Humans; In Vitro Techniques; Kinetics; Lung; Prostaglandins F; SRS-A	1977
The effects of the immunologic release of histamine upon human lung cyclic nucleotide levels and prostaglandin generation. The Journal of clinical investigation, 1978, Volume: 62, Issue:6 Topics: Anaphylaxis; Arachidonic Acids; Aspirin; Cyclic AMP; Cyclic GMP; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Prostaglandins F; SRS-A	1978
Inhibition by non-steroidal anti-inflammatory agents of the ascorbate-induced elevations of platelet cyclic AMP levels. Journal of cyclic nucleotide research, 1979, Volume: 5, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; 5,8,11,14-Eicosatetraynoic Acid; Anaerobiosis; Ascorbic Acid; Aspirin; Blood Platelets; Cyclic GMP; Enzyme Activation; Humans; Oxygen Consumption; Phospholipases A; Phospholipases A2	1979
Prostaglandins as intracellular messengers. Life sciences, 1975, Jun-01, Volume: 16, Issue:11 Topics: Adenylyl Cyclases; Animals; Arachidonic Acids; Aspirin; Blood Pressure; Calcium; Chemical Phenomena; Chemistry; Cyclic AMP; Cyclic GMP; Fatty Acids, Unsaturated; Feedback; Female; Hormones; Humans; Male; Models, Chemical; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Structure-Activity Relationship	1975
Roles of cyclic nucleotides in platelet function. Ciba Foundation symposium, 1975, Volume: 35 Topics: Acetylcholine; Adenosine Diphosphate; Adenylyl Cyclases; Arginine Vasopressin; Aspirin; Blood Platelets; Calcium; Carbachol; Collagen; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Papaverine; Platelet Aggregation; Prostaglandins E	1975
Effect of aspirin on normal and cholera toxin-stimulated intestinal electrolyte transport. The Journal of clinical investigation, 1976, Volume: 57, Issue:4 Topics: Animals; Aspirin; Biological Transport; Cholera; Cyclic AMP; Cyclic GMP; Electrolytes; Electrophysiology; Epinephrine; Ileum; Intestinal Absorption; Intestinal Mucosa; Ions; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Rabbits; Stimulation, Chemical; Toxins, Biological	1976
Possible relation of prostaglandins to PMN-derived mediators of host metabolic responses to inflammation. Prostaglandins, 1977, Volume: 13, Issue:1 Topics: Amino Acids; Animals; Aspirin; Biological Assay; Bucladesine; Cells, Cultured; Cyclic GMP; Cyclooxygenase Inhibitors; Indomethacin; Inflammation; Leukocyte Count; Mixed Function Oxygenases; Morphine; Neutrophils; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Zinc	1977
The involvement of prostaglandin endoperoxide formation in the elevation of cyclic GMP levels during platelet aggregation. Journal of cyclic nucleotide research, 1977, Volume: 3, Issue:1 Topics: Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Humans; Indomethacin; Peroxides; Platelet Aggregation; Prostaglandins	1977
Effects of blood glucose levels on aspirin-induced gastric mucosal damage. The American journal of digestive diseases, 1977, Volume: 22, Issue:10 Topics: Adrenal Cortex Hormones; Animals; Aspirin; Blood Glucose; Bucladesine; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Dibutyryl Cyclic GMP; Fasting; Female; Gastric Mucosa; Glucosamine; Glycoproteins; Hypoglycemia; Insulin; Rats; Stomach Ulcer	1977
Elevation of the cyclic GMP concentration in human platelets by sodium ascorbate and 5-hydroxytryptamine. Journal of cyclic nucleotide research, 1977, Volume: 3, Issue:5 Topics: Ascorbic Acid; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Humans; Serotonin; Thrombin	1977
The predominant contribution of platelets to baseline and ascorbate-stimulated increments in cyclic GMP in human mononuclear leukocyte preparations. Cellular immunology, 1978, Volume: 35, Issue:2 Topics: Ascorbic Acid; Aspirin; Blood Platelets; Carrier Proteins; Cyclic GMP; Humans; Indomethacin; Monocytes; Radioimmunoassay	1978
Sensitivity to cyclic nucleotides and to aspirin of the kininogen-consuming system activated by adrenaline or carbamylcholine in rat blood. Agents and actions, 1978, Volume: 8, Issue:1-2 Topics: Animals; Aspirin; Carbachol; Cyclic AMP; Cyclic GMP; Epinephrine; Kininogens; Kinins; Male; Muscle Contraction; Rats	1978
Divergent effects of prostaglandin synthesis inhibitors on pulmonary cyclic 3', 5'-adenosine monophosphate and cyclic 3', 5'-guanosine monophosphate levels in untreated and histamine sensitized mice. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 241, Issue:2 Topics: Animals; Aspirin; Cyclic AMP; Cyclic GMP; Female; Histamine; Indomethacin; Lung; Mice; Mice, Inbred ICR; Pertussis Vaccine; Prostaglandins	1979
The effect of low dose of 12-O-tetradecanoyl-phorbol-13-acetate on collagen platelet interactions. Thrombosis research, 1989, Jun-15, Volume: 54, Issue:6 Topics: Aspirin; Blood Platelets; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Microscopy, Electron; Phosphorylation; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate	1989
The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochemical and biophysical research communications, 1987, Nov-13, Volume: 148, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Extracellular Matrix; Humans; In Vitro Techniques; Nitric Oxide; Phthalazines; Platelet Adhesiveness; Purinones; Superoxide Dismutase; Thrombin	1987
Low-density lipoproteins increase intracellular calcium in aequorin-loaded platelets. FEBS letters, 1988, Oct-10, Volume: 238, Issue:2 Topics: Aequorin; Aspirin; Blood Platelets; Calcium; Cyclic GMP; Humans; Isoquinolines; Lipoproteins, LDL; Luminescence; Luminescent Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrahydroisoquinolines	1988
Mechanism of the inhibition of platelet aggregation produced by prostaglandin F2 alpha. Prostaglandins, 1985, Volume: 29, Issue:4 Topics: Adenosine Diphosphate; Aspirin; Cyclic AMP; Cyclic GMP; Dinoprost; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins F; Prostaglandins H; Prostaglandins, Synthetic; Thrombin	1985
Studies on the effect of different inhibitors of arachidonic acid metabolism on glyceryltrinitrate-induced relaxation and cGMP elevation in bovine vascular tissue. Pharmacology & toxicology, 1987, Volume: 60, Issue:2 Topics: Animals; Arachidonic Acids; Aspirin; Blood Vessels; Cattle; Cyclic GMP; In Vitro Techniques; Masoprocol; Muscle Contraction; Muscle Relaxation; Neuromuscular Depolarizing Agents; Nitroglycerin; Phenylephrine; Quinacrine; Tranylcypromine	1987
Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices. Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:12 Topics: Acetylcholine; Angiotensin II; Animals; Aspirin; Bradykinin; Culture Techniques; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Indomethacin; Isoproterenol; Lung; Peptides; Promethazine; Stimulation, Chemical; Theophylline	1973
Effects of collagen and of aspirin on the concentration of guanosine 3':5'-cyclic monophosphate in human blood platelets: measurement by a prelabelling technique. The Biochemical journal, 1974, Volume: 138, Issue:2 Topics: Aspirin; Blood Platelets; Chromatography, Thin Layer; Collagen; Cyclic GMP; Guanine; Humans; In Vitro Techniques; Platelet Adhesiveness; Time Factors; Tritium	1974
Studies on the role of cyclic GMP in the control of human platelet function. Biochemical Society transactions, 1980, Volume: 8, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acids; Aspirin; Blood Platelets; Cyclic GMP; Humans; Indomethacin	1980
Independent mechanisms for bradykinin-mediated prostaglandin E2 and cyclic GMP syntheses in rabbit renal inner medulla slices. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Bradykinin; Calcium; Cyclic GMP; Dinoprostone; In Vitro Techniques; Kidney Medulla; Prostaglandins E; Rabbits; Time Factors	1982
Interferon enhancement of natural killer cell cytotoxicity: role of cyclic nucleotides. Journal of interferon research, 1982, Volume: 2, Issue:4 Topics: Animals; Aspirin; Calcium; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Indomethacin; Interferons; Killer Cells, Natural; Lymphocytes; Mice; Mice, Inbred BALB C; Time Factors	1982
Treatment of canine spontaneous diabetes mellitus with aspirin. Metabolic and pediatric ophthalmology, 1980, Volume: 4, Issue:3 Topics: Animals; Aspirin; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, Animal; Dog Diseases; Dogs; Drug Therapy, Combination; Epoprostenol; Platelet Count	1980
Effects of 12-O-tetradecanoyl phorbol 13-acetate on platelet aggregation. Thrombosis research, 1981, Mar-15, Volume: 21, Issue:6 Topics: Aspirin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Phorbols; Phosphorylation; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate	1981
The effects of arachidonic acid, PGI2, and 6-keto-PGF1 alpha on cyclic nucleotide concentrations in a ventilated and artificially perfused isolated dog lung. Prostaglandins, leukotrienes, and medicine, 1982, Volume: 9, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclic AMP; Cyclic GMP; Dogs; Epoprostenol; In Vitro Techniques; Indomethacin; Kinetics; Lung; Perfusion; Prostaglandins; Tranylcypromine	1982
Simultaneous manipulation of the nitric oxide and prostanoid pathways reduces myocardial reperfusion injury. The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:4 Pt 1 Topics: Animals; Arginine; Aspirin; Cardioplegic Solutions; Coronary Circulation; Cyclic GMP; Glucose; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tromethamine; Vascular Resistance	1995
Role of NO mechanism in cardiovascular effects of diaspirin cross-linked hemoglobin in anesthetized rats. The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 2 Topics: Animals; Arginine; Arteries; Aspirin; Cardiovascular System; Cyclic GMP; Gases; Hemodynamics; Hemoglobins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium Chloride; Vascular Resistance	1995
Sodium nitroprusside, an endothelium-derived relaxing factor congener, increases platelet cyclic GMP levels and inhibits epinephrine-exacerbated in vivo platelet thrombus formation in stenosed canine coronary arteries. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4 Topics: Animals; Aspirin; Blood Platelets; Blood Pressure; Coronary Circulation; Coronary Thrombosis; Cyclic GMP; Disease Models, Animal; Dogs; Epinephrine; Heart Rate; Injections, Intravenous; Nitroprusside	1993
Role of cyclic nucleotides in rapid platelet adhesion to collagen. Blood, 1994, May-01, Volume: 83, Issue:9 Topics: Adenylyl Cyclases; Alprostadil; Antigens, CD; Apyrase; Aspirin; Blood Platelets; Collagen; Creatine Kinase; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Integrin beta1; Integrins; Nitroprusside; Platelet Adhesiveness	1994
Dilator prostanoid-induced cyclic AMP formation and release by cerebral microvascular smooth muscle cells: inhibition by indomethacin. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Animals, Newborn; Aspirin; Brain; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Enzyme Activation; Iloprost; In Vitro Techniques; Indomethacin; Microcirculation; Muscle, Smooth, Vascular; Receptors, Epoprostenol; Receptors, Prostaglandin; Signal Transduction; Swine	1995
What effect does controlling platelets have on atherosclerosis? Annals of the New York Academy of Sciences, 1995, Jan-17, Volume: 748 Topics: Adenylyl Cyclases; Animals; Arteriosclerosis; Aspirin; Blood Platelets; Calcium; Capillary Permeability; Cattle; Collagen; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Myocardial Ischemia; Nitric Oxide; Plasminogen Activator Inhibitor 1; Platelet Activation; Platelet Aggregation; Tissue Plasminogen Activator	1995
Contractile effects of diaspirin cross-linked hemoglobin (DCLHb) on isolated porcine blood vessels. The Journal of laboratory and clinical medicine, 1995, Volume: 125, Issue:6 Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Arteries; Aspirin; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Kinetics; Methemoglobin; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Organ Specificity; Potassium Chloride; Pulmonary Veins; Swine; Veins	1995
Potentiation of endogenous nitric oxide with superoxide dismutase inhibits platelet-mediated thrombosis in injured and stenotic arteries. Journal of the American College of Cardiology, 1995, Volume: 25, Issue:1 Topics: Animals; Arteries; Aspirin; Blood Platelets; Cardiovascular Agents; Constriction, Pathologic; Cyclic GMP; Drug Evaluation, Preclinical; Drug Synergism; Nitric Oxide; Nitroglycerin; Organometallic Compounds; Rabbits; Random Allocation; Superoxide Dismutase; Thrombosis; Time Factors	1995
Cholera toxin-induced small intestinal secretion has a secretory effect on the colon of the rat. Gastroenterology, 1995, Volume: 108, Issue:1 Topics: Animals; Aspirin; Biological Transport; Cholera Toxin; Colon; Cyclic GMP; Denervation; Electrolytes; Intestines; Jejunum; Male; Nervous System Physiological Phenomena; Osmolar Concentration; Rats; Rats, Wistar; Water	1995
Effects of aspirin on platelet-neutrophil interactions. Role of nitric oxide and endothelin-1. Circulation, 1995, Apr-01, Volume: 91, Issue:7 Topics: Animals; Aspirin; Blood Platelets; Calcium; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Rabbits	1995
Interaction of antiplatelet drugs in vitro: aspirin, iloprost, and the nitric oxide donors SIN-1 and sodium nitroprusside. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:4 Topics: Adenosine Triphosphate; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Drug Interactions; Humans; Iloprost; In Vitro Techniques; Iodine Radioisotopes; Molsidomine; Nitric Oxide; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors	1995
Prostacyclin and sodium nitroprusside inhibit the activity of the platelet inositol 1,4,5-trisphosphate receptor and promote its phosphorylation. The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10 Topics: Animals; Aspirin; Biological Transport; Blood Platelets; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cattle; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Epoprostenol; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Kinetics; Nitroprusside; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Serum Albumin, Bovine; Thrombin; Time Factors	1996
Inhibition of acute stent thrombosis under high-shear flow conditions by a nitric oxide donor, DMHD/NO. An ex vivo porcine arteriovenous shunt study. Circulation, 1996, Nov-01, Volume: 94, Issue:9 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Cyclic GMP; Hemodynamics; Heparin; Hexanones; Nitric Oxide; Platelet Aggregation; Stents; Swine; Thrombosis; Whole Blood Coagulation Time	1996
Crosslinked hemoglobin inhibits endothelium-dependent relaxations in isolated canine arteries. General pharmacology, 1996, Volume: 27, Issue:2 Topics: Acetylcholine; Animals; Aspirin; Blood Substitutes; Calcimycin; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Hemoglobins; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Artery; Vasodilation	1996
Diaspirin cross-linked hemoglobin does not alter isolated human umbilical artery or vein tone. Artificial cells, blood substitutes, and immobilization biotechnology, 1996, Volume: 24, Issue:6 Topics: Acetylcholine; Animals; Aspirin; Cyclic GMP; Dose-Response Relationship, Drug; Hemoglobins; Humans; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Serotonin; Substance P; Swine; Umbilical Arteries; Umbilical Veins; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	1996
The antiplatelet effects of a new nitroderivative of acetylsalicylic acid--an in vitro study of inhibition on the early phase of platelet activation and on TXA2 production. Thrombosis and haemostasis, 1996, Volume: 76, Issue:5 Topics: Adult; Aspirin; Blood Platelets; Calcium; Cyclic GMP; Humans; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thromboxane A2	1996
Role of ET and NO in resuscitative effect of diaspirin cross-linked hemoglobin after hemorrhage in rat. The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 2 Topics: Animals; Aspirin; Blood Substitutes; Cyclic GMP; Endothelin-1; Endothelins; Enzyme Inhibitors; Gases; Hemodynamics; Hemoglobins; Hemorrhage; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resuscitation; Survival Analysis	1997
Regional differentiation in the rat aorta: effects of cyclooxygenase inhibitors. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Aorta, Abdominal; Aorta, Thoracic; Aspirin; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Prostaglandin H2; Prostaglandins H; Rats; Rats, Sprague-Dawley	1997
Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. The American journal of physiology, 1997, Volume: 273, Issue:4 Topics: Aspirin; Blood Platelets; Blotting, Western; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Cytosol; Humans; Indomethacin; Nitric Oxide Synthase; Osmolar Concentration; Thromboxane B2	1997
Triggering of beta 1-integrin chain induces platelet adhesion to cultured endothelium. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11 Topics: Alprostadil; Animals; Antibodies, Monoclonal; Aspirin; Azepines; Blood Platelets; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Matrix Proteins; Humans; Integrin beta1; Mice; Mice, Inbred BALB C; Nitroprusside; P-Selectin; Platelet Adhesiveness; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Thienopyridines; Triazoles	1997
Comparison of in vitro effects of triflusal and acetysalicylic acid on nitric oxide synthesis by human neutrophils. European journal of pharmacology, 1998, Feb-05, Volume: 343, Issue:1 Topics: Aspirin; Cyclic GMP; Cyclooxygenase Inhibitors; Humans; Neutrophils; Nitric Oxide; Platelet Aggregation Inhibitors; Salicylates	1998
Effect of some cyclooxygenase inhibitors on the increase in guanosine 3':5'-cyclic monophosphate induced by NO-donors in human whole platelets. British journal of pharmacology, 1998, Volume: 123, Issue:7 Topics: Acetophenones; Aspirin; Blood Platelets; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Indoprofen; Nitric Oxide; Nitroprusside; Penicillamine; Phospholipases A; Thromboxane B2	1998
Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets. FEBS letters, 1999, Jan-15, Volume: 442, Issue:2-3 Topics: Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Cyclic GMP; Cysteine; Fatty Acids, Unsaturated; Glutathione; Guanylate Cyclase; Humans; Hydrazines; Inhibitory Concentration 50; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Thromboxane A2	1999
Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats. Gastroenterology, 1999, Volume: 116, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Caspases; Cyclic GMP; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; In Situ Nick-End Labeling; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Salicylates; Time Factors; Tumor Necrosis Factor-alpha; U937 Cells	1999
Effect of dipyridamole and aspirin on the platelet-neutrophil interaction via the nitric oxide pathway. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: Adult; Aspirin; Blood Platelets; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Humans; Male; Neutrophils; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors	2000
A common pathway for nitric oxide release from NO-aspirin and glyceryl trinitrate. Biochemical and biophysical research communications, 2000, Jul-21, Volume: 274, Issue:1 Topics: Animals; Aspirin; Cell Line; Cyclic GMP; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Imidazoles; Kidney; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Protein Binding; Swine	2000
The nitroderivative of aspirin, NCX 4016, reduces infarct size caused by myocardial ischemia-reperfusion in the anesthetized rat. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: Animals; Arrhythmias, Cardiac; Aspirin; Creatine Kinase; Cyclic GMP; Fibrinolytic Agents; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Peroxidase; Platelet Aggregation Inhibitors; Rats; Rats, Wistar	2001
NCX4016 (NO-Aspirin) has multiple inhibitory effects in LPS-stimulated human monocytes. British journal of pharmacology, 2001, Volume: 134, Issue:4 Topics: Aspirin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guanylate Cyclase; Humans; Interleukin-6; Lipopolysaccharides; Monocytes; Nitric Oxide; Oxadiazoles; Quinoxalines; Thromboplastin; Thromboxane B2; Tumor Necrosis Factor-alpha	2001
Effects of low-dose aspirin on endothelial function in hypertensive patients. Clinical cardiology, 2001, Volume: 24, Issue:11 Topics: Aged; Aspirin; Blood Volume; Case-Control Studies; Cyclic GMP; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Regional Blood Flow; Vasodilation; Vasodilator Agents	2001
Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Abdominal; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Male; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Prothrombin Time; Radioimmunoassay; Rats; Rats, Wistar; Shikimic Acid; Thrombin Time; Thrombosis; Thromboxane B2	2002
Aspirin protected the nitric oxide/cyclic GMP generating system in human peritoneum. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2001, Volume: 21 Suppl 3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Escherichia coli; Guanylate Cyclase; Humans; Immunohistochemistry; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peritoneum; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase	2001
NCX 4016, a nitric oxide-releasing aspirin, modulates adrenergic vasoconstriction in the perfused rat tail artery. British journal of pharmacology, 2002, Volume: 137, Issue:2 Topics: Animals; Arteries; Aspirin; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Perfusion; Rats; Rats, Wistar; Tail; Vasoconstriction	2002
Nitric oxide donating aspirins: novel drugs for the treatment of saphenous vein graft failure. The Annals of thoracic surgery, 2003, Volume: 75, Issue:5 Topics: Aged; Aspirin; Cell Division; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation Inhibitors; Saphenous Vein; Vasodilation	2003
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway. Arteriosclerosis, thrombosis, and vascular biology, 2003, Aug-01, Volume: 23, Issue:8 Topics: Animals; Aspirin; Cattle; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic N-Oxides; Cytoprotection; Diclofenac; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Imidazoles; Indomethacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine	2003
Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1 Topics: Animals; Arteries; Aspirin; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Nitrates; Nitric Oxide Donors; Nitrites; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tail; Thromboxane B2; Time Factors; Vasoconstriction	2003
Growth inhibition of human colon cancer cells by nitric oxide (NO)-donating aspirin is associated with cyclooxygenase-2 induction and beta-catenin/T-cell factor signaling, nuclear factor-kappaB, and NO synthase 2 inhibition: implications for chemopreventi Cancer research, 2003, Nov-15, Volume: 63, Issue:22 Topics: Aspirin; beta Catenin; Cell Nucleus; Colonic Neoplasms; Cyclic GMP; Cyclooxygenase 2; Cytoskeletal Proteins; DNA, Neoplasm; HT29 Cells; Humans; Isoenzymes; Membrane Proteins; NF-kappa B; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Trans-Activators; Transcription Factors	2003
Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens. Molecular human reproduction, 2005, Volume: 11, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Androgens; Animals; Aspirin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Myocytes, Smooth Muscle; Nitric Oxide; Nitro Compounds; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rabbits; RNA, Messenger; Vas Deferens	2005
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives. European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors	2005
Aspirin reduces endothelial cell senescence. Biochemical and biophysical research communications, 2005, Sep-09, Volume: 334, Issue:4 Topics: Aspirin; Cells, Cultured; Cellular Senescence; Cyclic GMP; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species	2005
The role of insulin dependent NO synthesis in the impaired production of maspin in human breast cancer. Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:6 Topics: Aged; Alprostadil; Aspirin; Binding, Competitive; Breast Neoplasms; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Genes, Tumor Suppressor; Humans; Insulin; Middle Aged; Neutrophils; Nitric Oxide; Receptor, Insulin; Sensitivity and Specificity; Serpins; Time Factors; Up-Regulation	2006
Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors. European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3 Topics: Adenosine Triphosphate; Adult; Aspirin; Caffeic Acids; Cell Line, Tumor; Chlamydophila pneumoniae; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Flavanones; Humans; Lipoxygenase Inhibitors; Piroxicam; Platelet Activating Factor; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12	2007
The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-alpha, a potent inhibitor of platelet aggregation and a thrombolytic agent. Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:2 Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Female; Fibrin; Fibrinolysis; Humans; Interferon-alpha; Leukocytes; Male; Mice; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Thrombosis	2009
Aspirin acetylates nitric oxide synthase type 3 in platelets thereby increasing its activity. Cardiovascular research, 2009, Jul-01, Volume: 83, Issue:1 Topics: Acetylation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Serine; Transfection; Young Adult	2009
Shear-dependent suppression of platelet thrombus formation by phosphodiesterase 3 inhibition requires low levels of concomitant Gs-coupled receptor stimulation. Thrombosis and haemostasis, 2011, Volume: 105, Issue:3 Topics: Aspirin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gs; Hemostasis; Humans; Ligands; Platelet Aggregation; Quinolines; Ristocetin; Shear Strength; Tirofiban; Tyrosine; Urea; von Willebrand Factor	2011
Characterization of a unique dihydropyrimidinone, ethyl 4-(4'-heptanoyloxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylate, as an effective antithrombotic agent in a rat experimental model. The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:9 Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Drug Synergism; Inflammation Mediators; Inhibitory Concentration 50; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Thrombin; Thromboplastin; Thrombosis	2011
High glucose inhibits the aspirin-induced activation of the nitric oxide/cGMP/cGMP-dependent protein kinase pathway and does not affect the aspirin-induced inhibition of thromboxane synthesis in human platelets. Diabetes, 2012, Volume: 61, Issue:11 Topics: Adult; Amifostine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cell Adhesion Molecules; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Resistance; Female; Humans; Hyperglycemia; Lysine; Male; Microfilament Proteins; Nitric Oxide; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Protein Processing, Post-Translational; Second Messenger Systems; Thromboxanes; Vasodilator Agents; Young Adult	2012
Angiogenic impairment of the vascular endothelium: a novel mechanism and potential therapeutic target in muscular dystrophy. Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:12 Topics: Animals; Apoptosis; Aspirin; Carcinoma, Lewis Lung; Caveolin 1; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Coculture Techniques; Corneal Neovascularization; Cyclic GMP; Disease Models, Animal; Dystrophin; Endothelial Cells; Endothelium, Vascular; Ischemia; Mice; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Mutation; Myoblasts, Skeletal; Neovascularization, Pathologic; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Time Factors	2013
Antinociceptive activity of a synthetic oxopyrrolidine-based compound, ASH21374, and determination of its possible mechanisms. Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:12 Topics: Analgesics; Analgesics, Opioid; Animals; Aspirin; Capsaicin; Cyclic GMP; Glutamic Acid; Male; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Naloxone; Naltrexone; Nitric Oxide; Pyrrolidines; Rats, Sprague-Dawley; Receptors, Opioid	2013
Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets. Thrombosis research, 2018, Volume: 171 Topics: Arachidonic Acid; Aspirin; Blood Platelets; Cell Survival; Cyclic AMP; Cyclic GMP; Drug Resistance; Humans; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Protein Kinases	2018
Aspirin eugenol ester inhibits agonist-induced platelet aggregation in vitro by regulating PI3K/Akt, MAPK and Sirt 1/CD40L pathways. European journal of pharmacology, 2019, Jun-05, Volume: 852 Topics: Animals; Aspirin; Calcium; Caspase 3; CD40 Ligand; Cell Adhesion Molecules; Cyclic AMP; Cyclic GMP; Eugenol; Gene Expression Regulation; Intracellular Space; L-Lactate Dehydrogenase; Male; MAP Kinase Signaling System; Microfilament Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Platelet Aggregation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Sirtuin 1; Thromboxane A2	2019