aspirin and bis(3,5-dibromosalicyl)fumarate

aspirin has been researched along with bis(3,5-dibromosalicyl)fumarate in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199023 (38.98)18.7374
1990's31 (52.54)18.2507
2000's5 (8.47)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caballero, R; Hess, J; Reiss, RF1
Dittmer, J; Giorgio, A; Ichikura, T; Pivacek, LE; Prusty, S; Valeri, CR1
Bradley, K; Cole, DJ; Drummond, JC; Przybelski, RJ; Schell, RM1
DeYoung, A; Fowler, SA; Kwiatkowski, LD; Noble, RW; Walder, J1
Hiraiwa, H; Hirata, H; Imai, K; Morimoto, H; Saigo, S; Shibayama, N1
Brown, D; Flokas, K; Kosek, JC; Mondon, CE; Starnes, HF; Tewari, A; Van-Kessel, AL1
Bauman, RA; Bounds, MJ; Przybelski, RJ1
Olsen, KW; Yang, T4
Bucci, E; Fronticelli, C; Gryczynski, Z; Razynska, A; Sznajder, J; Urbaitis, B1
Chavez, MD; Courtney, SH; Friedman, JM; Hirsch, RE; Larsen, RW; Lin, MJ; Ondrias, MR1
Bellelli, A; Brancaccio, A; Brunori, M; Ippoliti, R; Lendaro, E1
Bowman, PD; Bunch, D; Hess, JR; McKinney, LA; Schuschereba, ST; Smith, CD1
Klinker, MT; Macdonald, VW; Marini, MA; Winslow, RM1
Bowman, PD; Bunch, D; Clifford, CB; Schuschereba, ST; Vargas, JA1
Clifford, CB; Smith, CD; Wessels, DA1
Adachi, K; Nibu, K1
Bangal, NR; Fadare, SO; Hess, JR; Tolentino, LS; Winslow, RM1
Apstein, CS; Lieberthal, W; Valeri, CR; Vogel, WM1
Marini, MA; Medina, F; Vandegriff, KD; Winslow, RM1
Arnone, A; Chatterjee, R; Pruitt, SL; Rogers, PH; Walder, JA; Walder, RY; Welty, EV1
Snyder, SR; Walder, JA; Walder, RY; Welty, EV; Williams, LA1
Olsen, KW; White, FL1
Arai, M; Kikugawa, K1
Klotz, IM; Thompson, EB2
Bookchin, RM; Chang, H; Ewert, SM; Nagel, RL1
Ho, C; Miura, S2
Chatterjee, R; Iwai, Y; Walder, JA; Walder, RY1
Adachi, K; Asakura, T; Kikugawa, K; Kosugi, H1
Adachi, K; Asakura, T; Kikugawa, K1
Arnone, A; Chatterjee, R; Walder, JA; Walder, RY1
Bolin, RB; Irion, GS; Knopp, GL; McLaughlin, SK; Medina, F; Tye, RW1
Mentzer, WC1
Clare, SE; Haney, DN; King, LC; Klotz, IM; Patel, JR; Shi, GY; Wood, LE1
Foresti, R; Motterlini, R; Vandegriff, K; Winslow, RM1
Macdonald, VW; Motterlini, R1
Imai, K; Morimoto, H; Saigo, S; Shibayama, N1
Alayash, AI; Cashon, RE; Rogers, MS; Ryan, BB1
Alayash, AI; Cashon, RE1
Motterlini, R; Rovida, E; Samaja, M1
Huang, H; Olsen, KW1
Andracki, ME; Walder, JA; Walder, RY1
Cassidy, G; Crowley, JP; Gray, A; Metzger, J; Pivacek, LE; Valeri, CR1
Alayash, AI; Darbyshire, JF; Meyer, CA; Osawa, Y1
Cole, DJ; Drummond, JC; Reynolds, L; Schell, RM1
Alayash, AI; Bonaventura, C; Bonaventura, J; Cashon, RE; Fratantoni, JC1
Abassi, Z; Abouassali, M; Alayash, AI; Fratantoni, JC; Keiser, HR; Kotob, S; Pieruzzi, F1
Burlingame, AL; Friso, G; Lo-Tseng, T; Miranda, JJ; Moore, EG; Patel, MJ; Yu, Z1
Alayash, AI; Breyer, RJ; Brockner-Ryan, BA; Goldman, DW; Yeh, D1
Dick, LA; Heibel, G; Moore, EG; Spiro, TG1
Abad-Zapatero, C; Fernandez, EJ; Olsen, KW1
Cai, J; Hong, M; Li, SY; Meng, WF; Yuan, ZY1
Davey, RJ1
Jin, C; Min, H; Pei-Lin, C; Wen-Fang, M; Zhong-Yi, Y1
Huang, L; Liang, WG; Wang, B; Wang, X; Yang, CM1

Reviews

2 review(s) available for aspirin and bis(3,5-dibromosalicyl)fumarate

ArticleYear
Comparative evaluation of fifteen anti-sickling agents.
    Blood, 1983, Volume: 61, Issue:4

    Topics: Anemia, Sickle Cell; Antisickling Agents; Aspirin; Azepines; Carbamyl Phosphate; Cyanates; Cystamine; Dimethyl Adipimidate; Drug Evaluation; Erythrocyte Indices; Glyceraldehyde; Hemoglobins; Humans; Imidoesters; Mechlorethamine; Oxygen Consumption; Phenylalanine; Pyridoxal; Solubility; Urea

1983
Overcoming blood shortages: red blood cell and platelet substitutes and membrane modifications.
    Current hematology reports, 2004, Volume: 3, Issue:2

    Topics: Animals; Aspirin; Blood Donors; Blood Platelets; Blood Preservation; Blood Substitutes; Blood Transfusion; Cattle; Clinical Trials as Topic; Cross-Linking Reagents; Cryopreservation; Drug Combinations; Erythrocyte Membrane; Fluorocarbons; Glycoside Hydrolases; Hemoglobins; Humans; Hydroxyethyl Starch Derivatives

2004

Other Studies

57 other study(ies) available for aspirin and bis(3,5-dibromosalicyl)fumarate

ArticleYear
Effects of X-linked hemoglobin on in-vitro platelet function.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1992, Volume: 20, Issue:2-4

    Topics: Aspirin; Blood Substitutes; Cross-Linking Reagents; Hemoglobins; Humans; In Vitro Techniques; Platelet Aggregation

1992
Intravascular circulation and distribution of human 51Cr-DBBF stroma-free hemoglobin.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1992, Volume: 20, Issue:2-4

    Topics: Animals; Aspirin; Blood Substitutes; Cross-Linking Reagents; Half-Life; Hemoglobins; Humans; Male; Mice; Tissue Distribution

1992
Focal cerebral ischemia in rats: effect of hemodilution with alpha-alpha cross-linked hemoglobin on CBF.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:6

    Topics: Animals; Aspirin; Brain; Brain Ischemia; Cerebrovascular Circulation; Cross-Linking Reagents; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodilution; Hemoglobins; Male; Rats; Rats, Inbred SHR

1992
Isolation and characterization of the triply oxidized derivative of a cross-linked hemoglobin.
    Biochemistry, 1992, Jan-28, Volume: 31, Issue:3

    Topics: Aspirin; Carbon Dioxide; Cross-Linking Reagents; Cyanides; Hemoglobin A; Humans; Isoelectric Focusing; Kinetics; Macromolecular Substances; Oxyhemoglobins; Phytic Acid

1992
Oxygen equilibrium properties of highly purified human adult hemoglobin cross-linked between 82 beta 1 and 82 beta 2 lysyl residues by bis(3,5-dibromosalicyl) fumarate.
    Biochemistry, 1991, Aug-20, Volume: 30, Issue:33

    Topics: Adult; Amino Acid Sequence; Aspirin; Cross-Linking Reagents; Hemoglobins; Humans; Lysine; Molecular Sequence Data; Oxyhemoglobins

1991
Effectiveness of a purified human hemoglobin as a blood substitute in the perfused rat liver.
    Gastroenterology, 1991, Volume: 101, Issue:5

    Topics: Analysis of Variance; Animals; Aspirin; Bile; Blood Substitutes; Cross-Linking Reagents; Erythrocytes; Fluorocarbons; Glucose; Hemoglobins; Humans; Isotonic Solutions; Lactates; Lactic Acid; Liver; Male; Microscopy, Electron; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains

1991
The effects of alpha-alpha cross-linked hemoglobin on the feeding and locomotor activity of rats.
    Physiology & behavior, 1991, Volume: 50, Issue:1

    Topics: Animals; Appetitive Behavior; Aspirin; Blood Substitutes; Body Weight; Circadian Rhythm; Cross-Linking Reagents; Eating; Hemorrhage; Male; Motor Activity; Rats; Rats, Inbred Strains

1991
Thermal stability of hemoglobin crosslinked in the T-state by bis(3,5-dibromosalicyl) fumarate.
    Biochemical and biophysical research communications, 1991, Jan-31, Volume: 174, Issue:2

    Topics: Amino Acids; Aspirin; Cross-Linking Reagents; Drug Stability; Globins; Hemoglobin A; Hemoglobins; Humans; Macromolecular Substances; Protein Denaturation; Thermodynamics

1991
Bovine hemoglobin pseudo-crosslinked with mono(3,5-dibromosalicyl)-fumarate.
    European journal of biochemistry, 1990, Oct-24, Volume: 193, Issue:2

    Topics: Animals; Aspirin; Cattle; Centrifugation, Density Gradient; Cross-Linking Reagents; Electrochemistry; Half-Life; Hemoglobins; Molecular Structure; Oxygen; Peptide Fragments; Peptide Mapping; Rats

1990
Dynamics and reactivity of HbXL99 alpha. A cross-linked hemoglobin derivative.
    The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8

    Topics: Aspirin; Carbon Monoxide; Cross-Linking Reagents; Fluorescence; Hemoglobin A; Hemoglobins; Hydrogen-Ion Concentration; Photolysis; Spectrum Analysis, Raman; Tryptophan

1990
Cooperative ligand binding of crosslinked hemoglobins at very high temperatures.
    Journal of molecular biology, 1990, Jun-20, Volume: 213, Issue:4

    Topics: Aspirin; Carbon Monoxide; Cross-Linking Reagents; Hemoglobins; Humans; Kinetics; Ligands; Macromolecular Substances; Oxygen; Photolysis; Protein Conformation; Protein Denaturation; Temperature; Thermodynamics

1990
Liver and kidney injury after administration of hemoglobin cross-linked with bis(3,5-dibromosalicyl) fumarate.
    Biomaterials, artificial cells, and artificial organs, 1990, Volume: 18, Issue:2

    Topics: Animals; Aspirin; Blood Substitutes; Cross-Linking Reagents; Female; Hemoglobins; Humans; Kidney; Liver; Swine

1990
Coronary vasoconstrictor activity of purified and modified human hemoglobin.
    Biomaterials, artificial cells, and artificial organs, 1990, Volume: 18, Issue:2

    Topics: Animals; Aspirin; Blood Substitutes; Coronary Vessels; Cross-Linking Reagents; Hemoglobins; In Vitro Techniques; Male; Perfusion; Rabbits; Vasoconstriction

1990
Morphologic alterations in rat retina after hypervolemic infusion of cross-linked hemoglobin.
    Biomaterials, artificial cells, and artificial organs, 1990, Volume: 18, Issue:2

    Topics: Animals; Aspirin; Blood Substitutes; Blood Volume; Blood-Retinal Barrier; Cross-Linking Reagents; Hemoglobins; Microscopy, Electron; Pigment Epithelium of Eye; Rats; Retina

1990
Morphologic effects of hypervolemic administration of DBBF hemoglobin in the rat.
    Biomaterials, artificial cells, and artificial organs, 1990, Volume: 18, Issue:2

    Topics: Animals; Aspirin; Blood Substitutes; Blood Volume; Cross-Linking Reagents; Heart; Hemoglobins; Liver; Male; Myocardium; Pulmonary Edema; Rats; Rats, Inbred Strains

1990
Effect of FS (alpha 2 gamma beta s) hybrid hemoglobin on Hb S nucleation and aggregation.
    Biochimica et biophysica acta, 1985, May-20, Volume: 829, Issue:1

    Topics: Aspirin; Cross-Linking Reagents; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; In Vitro Techniques; Kinetics; Oxygen; Protein Conformation; Structure-Activity Relationship

1985
The intravascular persistence of crosslinked human hemoglobin.
    Progress in clinical and biological research, 1989, Volume: 319

    Topics: Animals; Aspirin; Blood Substitutes; Cross-Linking Reagents; Dose-Response Relationship, Drug; Half-Life; Hemoglobins; Hemoglobinuria; Humans; Macaca mulatta; Polymers; Rabbits; Rats; Species Specificity; Swine

1989
Studies of the mechanism of the vasoconstrictor activity of stroma-free hemoglobin in the isolated perfused rat kidney and rabbit heart.
    Progress in clinical and biological research, 1989, Volume: 319

    Topics: Acetylcholine; Animals; Aspirin; Coronary Vessels; Cross-Linking Reagents; Hemoglobins; In Vitro Techniques; Male; Nitroprusside; Perfusion; Phosphatidylethanolamines; Phosphatidylserines; Plasma Substitutes; Rabbits; Rats; Rats, Inbred Strains; Renal Circulation; Serum Albumin, Bovine; Vasoconstriction; Vasoconstrictor Agents

1989
Thermal stability and cross-linking of Hb New York [beta 113(G15)Val----Glu].
    Hemoglobin, 1989, Volume: 13, Issue:2

    Topics: Aspirin; Chromatography, Ion Exchange; Cross-Linking Reagents; Drug Stability; Electrophoresis; Hemoglobins, Abnormal; Hot Temperature; Humans

1989
The effect of crosslinking by bis(3,5-dibromosalicyl) fumarate on the autoxidation of hemoglobin.
    Biochemical and biophysical research communications, 1989, Sep-15, Volume: 163, Issue:2

    Topics: Aspirin; Cross-Linking Reagents; Hemoglobin A; Kinetics; Methemoglobin; Oxidation-Reduction; Oxyhemoglobins

1989
Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate.
    The Journal of biological chemistry, 1989, Oct-25, Volume: 264, Issue:30

    Topics: 2,3-Diphosphoglycerate; Allosteric Regulation; Aspirin; Cross-Linking Reagents; Diphosphoglyceric Acids; Hemoglobin A; Humans; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mathematics; Models, Theoretical; Oxyhemoglobins; Phytic Acid

1989
Isolation and characterization of a new hemoglobin derivative cross-linked between the alpha chains (lysine 99 alpha 1----lysine 99 alpha 2).
    The Journal of biological chemistry, 1986, Jul-25, Volume: 261, Issue:21

    Topics: Amino Acid Sequence; Aspirin; Cross-Linking Reagents; Crystallography; Hemoglobins; Humans; Isoelectric Focusing; Lysine; Mathematics; Molecular Conformation; Oxyhemoglobins; Stereoisomerism; X-Ray Diffraction

1986
Effects of crosslinking on the thermal stability of hemoglobins. II. The stabilization of met-, cyanomet-, and carbonmonoxyhemoglobins A and S with bis(3,5-dibromosalicyl) fumarate.
    Archives of biochemistry and biophysics, 1988, Volume: 261, Issue:2

    Topics: Aspirin; Carboxyhemoglobin; Cross-Linking Reagents; Electrophoresis; Hemoglobin, Sickle; Methemoglobin; Protein Binding; Protein Denaturation; Temperature

1988
HbXL99 alpha: a hemoglobin derivative that is cross-linked between the alpha subunits is useful as a blood substitute.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:20

    Topics: Animals; Aspirin; Blood Substitutes; Blood Transfusion; Cross-Linking Reagents; Half-Life; Hemoglobin A2; Hemoglobins; Kidney; Male; Methemoglobin; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Rats; Rats, Inbred Strains

1987
Effects of crosslinking on the thermal stability of hemoglobin. I. The use of bis(3,5-dibromosalicyl) fumarate.
    Archives of biochemistry and biophysics, 1987, Volume: 258, Issue:1

    Topics: Aspirin; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hemoglobin A; Hot Temperature; Humans; Macromolecular Substances; Methemoglobin; Protein Denaturation; Spectrophotometry

1987
Studies on the intermediates of methemoglobin by the use of a cross-linking agent.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:3

    Topics: Aspirin; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Hemoglobins; Humans; Methemoglobin

1986
Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antisickling Agents; Aspirin; Body Temperature; Male; Mice; Rats; Rats, Inbred Strains

1985
Proton nuclear magnetic resonance investigation of cross-linked asymmetrically modified hemoglobins: influence of the salt bridges on tertiary and quaternary structures of hemoglobin.
    Biochemistry, 1984, May-22, Volume: 23, Issue:11

    Topics: Aspirin; Cross-Linking Reagents; Hemoglobin A; Hemoglobin C; Hemoglobins; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Protein Conformation; Structure-Activity Relationship

1984
Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site.
    The Journal of biological chemistry, 1984, Dec-10, Volume: 259, Issue:23

    Topics: 2,3-Diphosphoglycerate; Antisickling Agents; Aspirin; Binding Sites; Biological Transport; Cross-Linking Reagents; Diphosphoglyceric Acids; Hemoglobin, Sickle; Humans; Indicators and Reagents; Kinetics; Protein Binding; Structure-Activity Relationship

1984
Formation of cross-linked asymmetrical hybrid hemoglobins by double-headed aspirin.
    Hemoglobin, 1983, Volume: 7, Issue:6

    Topics: Aspirin; Blood Protein Electrophoresis; Chromatography, Gel; Chromatography, Ion Exchange; Cross-Linking Reagents; Electrophoresis, Cellulose Acetate; Hemoglobin A; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Oxyhemoglobins

1983
Effect of cross-linking between 82 beta 1 and 82 beta 2 lysyl residues on the kinetics of polymerization of deoxyhemoglobin S.
    The Journal of biological chemistry, 1982, Jul-10, Volume: 257, Issue:13

    Topics: Aspirin; Cross-Linking Reagents; Drug Stability; Hemoglobin, Sickle; Humans; Kinetics; Lysine; Macromolecular Substances; Oxyhemoglobins

1982
Mechanism for the increase in solubility of deoxyhemoglobin S due to cross-linking the beta chains between lysine-82 beta 1 and lysine-82 beta 2.
    Biochemistry, 1982, Nov-09, Volume: 21, Issue:23

    Topics: 2,3-Diphosphoglycerate; Aspirin; Carboxyhemoglobin; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Diphosphoglyceric Acids; Hemoglobin A; Hemoglobin, Sickle; Humans; Lysine; Protein Conformation; Solubility; X-Ray Diffraction

1982
Modification of hemoglobin - tetrameric stabilization.
    Progress in clinical and biological research, 1983, Volume: 122

    Topics: Aspirin; Blood Substitutes; Cross-Linking Reagents; Drug Stability; Hemoglobins; Humans; Oxygen

1983
Pharmacological actions of diaspirins, potential antisickling agents I: A preliminary study.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 37, Issue:1

    Topics: Animals; Antisickling Agents; Aspirin; Lethal Dose 50; Mice; Motor Activity

1982
Inhibitors of sickling.
    The American journal of pediatric hematology/oncology, 1982,Fall, Volume: 4, Issue:3

    Topics: Antisickling Agents; Aspirin; Azepines; Benzopyrans; Cyanates; Erythrocyte Aging; Erythrocytes, Abnormal; Hemoglobin, Sickle; Hormones; Humans; In Vitro Techniques

1982
Preparation and proton nuclear magnetic resonance investigation of cross-linked mixed valency hybrid hemoglobins: models for partially oxygenated species.
    Biochemistry, 1982, Nov-23, Volume: 21, Issue:24

    Topics: Aspirin; Hemoglobin A; Hemoglobin C; Hemoglobins; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Oxyhemoglobins; Spectrophotometry

1982
Structural specificities in acylation of hemoglobin and sickle hemoglobin by diaspirins.
    The Journal of biological chemistry, 1981, Jul-10, Volume: 256, Issue:13

    Topics: Aspirin; Cross-Linking Reagents; Hemoglobin A; Hemoglobin, Sickle; Humans; Indicators and Reagents; Methods; Oxyhemoglobins; Protein Binding; Structure-Activity Relationship

1981
The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1995, Volume: 23, Issue:3

    Topics: Animals; Aspirin; Cells, Cultured; Cross-Linking Reagents; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Methemoglobin; Oxidation-Reduction; Oxidative Stress; Swine

1995
Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:5

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Aspirin; Coronary Circulation; Cross-Linking Reagents; Endothelium, Vascular; Heart Function Tests; Hemoglobins; Humans; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Parasympathetic Nervous System; Rabbits; Reactive Oxygen Species; Vasoconstriction

1993
Oxygen equilibrium properties of nickel(II)-iron(II) hybrid hemoglobins cross-linked between 82 beta 1 and 82 beta 2 lysyl residues by bis(3,5-dibromosalicyl)fumarate: determination of the first two-step microscopic Adair constants for human hemoglobin.
    Biochemistry, 1995, Apr-11, Volume: 34, Issue:14

    Topics: Aspirin; Cross-Linking Reagents; Hemoglobins; Humans; Iron; Lysine; Nickel; Oxygen; Protein Multimerization

1995
Effects of polymerization on the oxygen carrying and redox properties of diaspirin cross-linked hemoglobin.
    Biochimica et biophysica acta, 1995, Apr-27, Volume: 1248, Issue:2

    Topics: Aspirin; Carbon Monoxide; Cross-Linking Reagents; Hemoglobins; Oxidation-Reduction; Oxygen; Polymers

1995
Reaction of human hemoglobin HbA0 and two cross-linked derivatives with hydrogen peroxide: differential behavior of the ferryl intermediate.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Aspirin; Blood Substitutes; Cross-Linking Reagents; Hemoglobin A; Humans; Hydrogen Peroxide; Iron; Kinetics; Models, Chemical; Oxidation-Reduction; Spectrophotometry

1995
Enhanced oxidation of bis(3,5-dibromosalicyl) fumarate alpha-alpha cross linked hemoglobin by free radicals generated by xanthine/xanthine oxidase.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3

    Topics: Aspirin; Cross-Linking Reagents; Free Radicals; Half-Life; Hemoglobin A; Hemoglobins; Humans; In Vitro Techniques; Kinetics; Oxidation-Reduction; Oxyhemoglobins; Reactive Oxygen Species; Xanthine; Xanthine Oxidase; Xanthines

1994
Thermal stabilities of hemoglobins crosslinked with different length reagents.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3

    Topics: Aspirin; Blood Substitutes; Cross-Linking Reagents; Drug Stability; Hemoglobin A; Hemoglobins; Hot Temperature; Humans; Oxyhemoglobins; Protein Denaturation

1994
Preparation of intramolecularly cross-linked hemoglobins.
    Methods in enzymology, 1994, Volume: 231

    Topics: 2,3-Diphosphoglycerate; Aspirin; Binding Sites; Blood Substitutes; Cross-Linking Reagents; Diphosphoglyceric Acids; Hemoglobins; Humans; Isoelectric Point; Protein Conformation

1994
Infusion of stroma-free cross-linked hemoglobin during acute gram-negative bacteremia.
    Circulatory shock, 1993, Volume: 41, Issue:3

    Topics: Acute Disease; Animals; Aspirin; Bacteremia; Blood Pressure; Carbon Dioxide; Cross-Linking Reagents; Dogs; Female; Gram-Negative Bacterial Infections; Hemoglobins; Male; Nitric Oxide; Serum Albumin

1993
Differential susceptibilities of the prosthetic heme of hemoglobin-based red cell substitutes. Implications in the design of safer agents.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aspirin; Biological Transport; Blood Substitutes; Cross-Linking Reagents; Drug Design; Erythrocytes; Heme; Hemoglobins; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxygen

1993
Focal cerebral ischemia in rats. Effect of hypervolemic hemodilution with diaspirin cross-linked hemoglobin versus albumin on brain injury and edema.
    Anesthesiology, 1993, Volume: 78, Issue:2

    Topics: Albumins; Animals; Aspirin; Brain Edema; Brain Injuries; Brain Ischemia; Cross-Linking Reagents; Hemodilution; Hemoglobins; Male; Rats; Rats, Inbred SHR

1993
Nitric oxide binding to human ferrihemoglobins cross-linked between either alpha or beta subunits.
    Archives of biochemistry and biophysics, 1993, Volume: 303, Issue:2

    Topics: Aspirin; Cross-Linking Reagents; Drug Stability; Humans; Kinetics; Macromolecular Substances; Methemoglobin; Nitric Oxide; Oxidation-Reduction; Oxygen; Spectrophotometry

1993
Effects of polymerization on the hypertensive action of diaspirin cross-linked hemoglobin in rats.
    The Journal of laboratory and clinical medicine, 1997, Volume: 129, Issue:6

    Topics: Analysis of Variance; Animals; Aorta; Aspirin; Blood Pressure; Blood Substitutes; Cardiac Output; Cross-Linking Reagents; Endothelium, Vascular; Enzyme Induction; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hemoglobins; Humans; Hypertension; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polyethylene Glycols; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Stroke Volume; Vascular Resistance

1997
Structural characterization of human hemoglobin crosslinked by bis(3,5-dibromosalicyl) fumarate using mass spectrometric techniques.
    Protein science : a publication of the Protein Society, 1997, Volume: 6, Issue:12

    Topics: Amino Acid Sequence; Aspirin; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Hemoglobins; Humans; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Molecular Weight; Peptide Mapping

1997
Acellular hemoglobin-mediated oxidative stress toward endothelium: a role for ferryl iron.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Animals; Aorta; Apoptosis; Aspirin; Cattle; Cell Death; Cross-Linking Reagents; DNA Fragmentation; Endothelium, Vascular; Hemoglobin A; Hemoglobins; Hydrogen Peroxide; Iron Compounds; L-Lactate Dehydrogenase; Oxidative Stress; Polymers

1998
UV resonance Raman spectra reveal a structural basis for diminished proton and CO2 binding to alpha,alpha-cross-linked hemoglobin.
    Biochemistry, 1999, May-18, Volume: 38, Issue:20

    Topics: Anions; Aspirin; Binding Sites; Carbon Dioxide; Cross-Linking Reagents; Hemoglobins; Humans; Hydrogen Bonding; Protein Conformation; Protein Structure, Tertiary; Protons; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman

1999
Crystal structure of Lysbeta(1)82-Lysbeta(2)82 crosslinked hemoglobin: a possible allosteric intermediate.
    Journal of molecular biology, 2000, Mar-10, Volume: 296, Issue:5

    Topics: Allosteric Regulation; Amino Acid Sequence; Aspirin; Binding Sites; Cross-Linking Reagents; Crystallization; Crystallography, X-Ray; Dimerization; Heme; Hemoglobins; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Oxygen; Oxyhemoglobins; Protein Structure, Tertiary; Thermodynamics

2000
PEG and DBBF modified porcine hemoglobin and their oxygen-carrying capacity.
    Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 2002, Volume: 34, Issue:4

    Topics: Animals; Aspirin; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hemoglobins; Oxygen; Polyethylene Glycols; Prohibitins; Swine

2002
Chemically modified porcine hemoglobins and their biological properties.
    Protein and peptide letters, 2004, Volume: 11, Issue:4

    Topics: Allosteric Regulation; Animals; Aspirin; Blood Substitutes; Cross-Linking Reagents; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hemoglobins; Hydrogen-Ion Concentration; Male; Molecular Weight; Oxygen; Polyethylene Glycols; Prohibitins; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Swine

2004
DBBF modified human placenta hemoglobin through the alpha chains.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2008, Volume: 36, Issue:2

    Topics: Animals; Aspirin; Blood Substitutes; Enzyme Stability; Female; Hemoglobin A; Hemoglobins; Humans; Multiprotein Complexes; Placenta; Pregnancy; Prohibitins; Protein Subunits; Rats; Rats, Sprague-Dawley

2008