aspirin and benoxaprofen

aspirin has been researched along with benoxaprofen in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199022 (78.57)18.7374
1990's0 (0.00)18.2507
2000's1 (3.57)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Kumar, M; Sinha, VR; Thareja, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Przybilla, B; Ring, J; Ruzicka, T; Schwab-Przybilla, U1
Greaves, MW1
Barton, BE; Wheeler, L; WoldeMussie, E1
Andries, R; Bourgain, RH; Braquet, P; Decuyper, K1
Bagby, GF; O'Brien, WM1
Brune, K; Peskar, BA1
Rainsford, KD2
Acosta, D; Sorensen, EM1
Bonney, RJ; Galavage, M; Goldenberg, M; Humes, JL; Kuehl, FA; Sadowski, S; Subers, E1
Cooke, BA; Dix, CJ; Habberfield, AD; Sullivan, MH1
Fox, SA; Osborne, DJ; Rainsford, KD1
Carmichael, RH; Nash, JF; Ridolfo, AS; Spradlin, CT1
Mikulaschek, WM2
Crabtree, RE; Johnson, DW; Ridolfo, AS; Rockhold, FW1
Gum, OB1
Alarcon-Segovia, D1
Bach, GL1
Ashbrook, EM; Offen, WW; Ridolfo, AS; Rockhold, FW; Schmid, GE; Vogel, JA1
Rainsford, KD; Robins, PG; Walker, SA; Willis, CM1
Fournier, E; Ramon, P; Tonnel, AB; Voisin, C; Wallaert, B1

Reviews

3 review(s) available for aspirin and benoxaprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
    The Journal of rheumatology, 1985, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colitis; Digestive System; Esophagus; Female; Humans; Ibuprofen; Indomethacin; Liver; Male; Middle Aged; Pancreatitis; Phenylbutazone; Propionates; Sialadenitis

1985

Trials

6 trial(s) available for aspirin and benoxaprofen

ArticleYear
Long-term safety of benoxaprofen.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Blood Urea Nitrogen; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Ibuprofen; L-Lactate Dehydrogenase; Male; Middle Aged; Nail Diseases; Osteoarthritis; Peptic Ulcer; Photosensitivity Disorders; Propionates; Time Factors

1980
Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Indomethacin; Melena; Naproxen; Propionates; Prostaglandins; Sulindac; Time Factors

1980
Long-term efficacy and safety of benoxaprofen: comparison with aspirin and ibuprofen in patients with active rheumatoid arthritis.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Blood Sedimentation; Clinical Trials as Topic; Double-Blind Method; Female; Hematocrit; Hemoglobins; Humans; Ibuprofen; Male; Middle Aged; Patient Compliance; Propionates; Time Factors

1980
Long-term treatment of symptomatic osteoarthritis with benoxaprofen. Double-blind comparison with aspirin and ibuprofen.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Ibuprofen; Knee Joint; Male; Middle Aged; Movement; Osteoarthritis; Patient Compliance; Propionates; Time Factors

1980
Activated osteoarthrosis (osteoarthritis) and its treatment with indomethacin and benoxaprofen: a double-blind crossover study.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Propionates

1982
A double-blind study comparing benoxaprofen, aspirin, and benoxaprofen plus aspirin in patients with rheumatoid arthritis.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Propionates; Time Factors

1982

Other Studies

19 other study(ies) available for aspirin and benoxaprofen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Phototoxicity of non-steroidal anti-inflammatory drugs demonstrated in vitro by a photo-basophil-histamine-release test.
    Photo-dermatology, 1987, Volume: 4, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Carbazoles; Diclofenac; Histamine Release; Humans; In Vitro Techniques; Indoprofen; Ketoprofen; Leukocytes; Photosensitivity Disorders; Propionates; Thiophenes; Ultraviolet Rays

1987
Pharmacology and significance of nonsteroidal anti-inflammatory drugs in the treatment of skin diseases.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dermatitis; Eicosanoic Acids; Humans; Ibuprofen; Leukotriene B4; Lipoxygenase Inhibitors; Propionates; Prostaglandins; Skin; Skin Diseases

1987
The role of arachidonic acid metabolism in IL-3-induced proliferation.
    Immunopharmacology and immunotoxicology, 1988, Volume: 10, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cell Division; Cell Line; Indomethacin; Interleukin-3; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Propionates; Pyrazoles

1988
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis.
    Thrombosis research, 1988, May-01, Volume: 50, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine

1988
Modulation by drugs of leukotriene and prostaglandin production from mouse peritoneal macrophages.
    International journal of tissue reactions, 1985, Volume: 7, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetaminophen; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Dinoprostone; Dipyrone; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins E; Pyrazoles; Pyrazolones; SRS-A

1985
Structural damage and changes in eicosanoid metabolites in the gastric mucosa of rats and pigs induced by anti-inflammatory drugs of varying ulcerogenicity.
    International journal of tissue reactions, 1986, Volume: 8, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diflunisal; Gastric Mucosa; Indomethacin; Membrane Potentials; Microscopy, Electron; Phenylacetates; Piroxicam; Propionates; Prostaglandins; Rats; Stomach Ulcer; Sulindac; Swine; Thiazines

1986
Relative toxicities of several nonsteroidal antiinflammatory compounds in primary cultures of rat hepatocytes.
    Journal of toxicology and environmental health, 1985, Volume: 16, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; L-Lactate Dehydrogenase; Liver; Propionates; Rats; Rats, Inbred Strains; Time Factors

1985
Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.
    Biochemical pharmacology, 1983, Aug-01, Volume: 32, Issue:15

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Female; Guinea Pigs; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins; Pyrazoles; SRS-A; Zymosan

1983
Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis.
    The Biochemical journal, 1984, Apr-15, Volume: 219, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Catechols; In Vitro Techniques; Indomethacin; Leydig Cells; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Pregnenolone; Propionates; Pyrazoles; Rats; Testosterone

1984
Comparative effects of some non-steroidal anti-inflammatory drugs on the ultrastructural integrity and prostaglandin levels in the rat gastric mucosa: relationship to drug uptake.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 101

    Topics: Animals; Anti-Inflammatory Agents; Apazone; Aspirin; Chromatography, Gas; Dinoprostone; Gastric Mucosa; Indomethacin; Intestinal Absorption; Kinetics; Lipoxygenase; Male; Mass Spectrometry; Microscopy, Electron; Propionates; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2

1984
Microvascular injury during gastric mucosal damage by anti-inflammatory drugs in pigs and rats.
    Agents and actions, 1983, Volume: 13, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Gastric Mucosa; Indomethacin; Microcirculation; Propionates; Rats; Swine

1983
Pharmacokinetic studies of benoxaprofen after therapeutic doses with a review of related pharmacokinetic and metabolic studies.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Aspirin; Benzoxazoles; Capsules; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Male; Middle Aged; Particle Size; Propionates; Solutions; Stereoisomerism; Tablets

1980
Electron microscopic observations comparing the gastric mucosal damage induced in rats and pigs by benoxaprofen and aspirin, reflecting their differing actions as prostaglandin-synthesis-inhibitors.
    British journal of experimental pathology, 1982, Volume: 63, Issue:1

    Topics: Animals; Aspirin; Benzoxazoles; Female; Gastric Mucosa; Microscopy, Electron; Propionates; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Swine; Vacuoles

1982
An update on long-term efficacy and safety with benoxaprofen.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:2

    Topics: Alkaline Phosphatase; Anemia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Ibuprofen; Kidney Diseases; Osteoarthritis; Peptic Ulcer; Photosensitivity Disorders; Propionates; Time Factors

1982
[Does benoxaprofen permit the prevention of acetylsalicylic acid asthma].
    La Nouvelle presse medicale, 1982, Dec-04, Volume: 11, Issue:49

    Topics: Aspirin; Asthma; Humans; Propionates

1982