aspirin and 8-hydroxy-2'-deoxyguanosine

aspirin has been researched along with 8-hydroxy-2'-deoxyguanosine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kleinjans, JC; Lutgerink, JT; Schilderman, PA; ten Hoor, F; ten Vaarwerk, FJ; Van der Wurff, A1
Denda, A; Endoh, T; Horiguchi, K; Konishi, Y; Mizumoto, Y; Nakae, D; Noguchi, O; Tang, Q; Tsujiuchi, T1
Boulanger, E; Bulckaen, H; Corman, B; Creusy, C; Garçon, G; Gaxatte, C; Gosset, P; Prévost, G; Puisieux, F; Robitaille, G; Roquet, V; Shirali, P1
Cangemi, R; Carnevale, R; Celestini, A; Ferro, D; Loffredo, L; Martini, A; Pignatelli, P; Polimeni, L; Violi, F1
Isono, Y; Kawanishi, S; Kobayashi, H; Oikawa, S; Tada-Oikawa, S1
Ramkissoon, A; Wells, PG1
Gonçalves, LL; Lee, CJ; Wells, PG1
Cho, W; Gwag, BJ; Im, DS; Lee, JH; Lee, JK; Lee, YA; Lee, YB; Shin, JH; Springer, JE; Yun, BS1
Doguc, DK; Gultekin, F; Kara, Y; Kulac, E1

Other Studies

9 other study(ies) available for aspirin and 8-hydroxy-2'-deoxyguanosine

ArticleYear
Induction of oxidative DNA damage and early lesions in rat gastro-intestinal epithelium in relation to prostaglandin H synthase-mediated metabolism of butylated hydroxyanisole.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Aspirin; Biotransformation; Butylated Hydroxyanisole; Cell Division; Colon; Cyclooxygenase Inhibitors; Deoxyguanosine; Digestive System; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Food Additives; Hyperplasia; Inflammation; Liver; Male; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reactive Oxygen Species; Rectum; Stomach

1995
Prevention by acetylsalicylic acid of liver cirrhosis and carcinogenesis as well as generations of 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances caused by a choline-deficient, L-amino acid-defined diet in rats.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amino Acids; Animals; Arachidonic Acid; Aspirin; Choline Deficiency; Deoxyguanosine; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances

1994
Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcholine; Age Factors; Aging; Animals; Antioxidants; Aorta; Aspirin; Cardiovascular Diseases; Deoxyguanosine; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Models, Animal; Oxidative Stress; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2008
Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure.
    Cardiovascular research, 2008, Jun-01, Volume: 78, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Aged; Aged, 80 and over; Arachidonic Acids; Aspirin; Blood Platelets; Case-Control Studies; CD40 Ligand; Cyclooxygenase 1; Deoxyguanosine; Enzyme Inhibitors; Female; Heart Failure; Humans; Male; Middle Aged; NADPH Oxidases; Oxidative Stress; Phospholipase A2 Inhibitors; Phospholipases A2; Protein Kinase C; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha; Up-Regulation

2008
Damage to cellular and isolated DNA induced by a metabolite of aspirin.
    Mutation research, 2009, Feb-10, Volume: 661, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aspirin; Cell Line, Tumor; Comet Assay; Copper; Deoxyguanosine; DNA Breaks, Single-Stranded; DNA Damage; DNA, Neoplasm; Genes, Tumor Suppressor; HL-60 Cells; Humans; Hydroxybenzoates; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Models, Biological; NAD; Pancreatic Neoplasms; Reactive Oxygen Species

2009
Human prostaglandin H synthase (hPHS)-1 and hPHS-2 in amphetamine analog bioactivation, DNA oxidation, and cytotoxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Aspirin; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclooxygenase 1; Cyclooxygenase 2; Deoxyguanosine; DNA; Enzyme Activation; Humans; Methamphetamine; Oxidation-Reduction; Transfection

2011
Embryopathic effects of thalidomide and its hydrolysis products in rabbit embryo culture: evidence for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species (ROS)-mediated mechanism.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:7

    Topics: 5,8,11,14-Eicosatetraynoic Acid; 8-Hydroxy-2'-Deoxyguanosine; Animals; Aspirin; Brain; Deoxyguanosine; Embryo, Mammalian; Female; Hydrolysis; Limb Buds; Male; Molecular Structure; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Rabbits; Reactive Oxygen Species; Teratogens; Thalidomide; Tissue Culture Techniques

2011
Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2012, Volume: 122, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Binding Proteins; Cerebral Cortex; Deoxyguanosine; Dinoprostone; Disease Models, Animal; Encephalitis; Free Radical Scavengers; Free Radicals; Gene Expression Regulation; Humans; Ibuprofen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microglia; Motor Neurons; Oxidative Stress; Riluzole; Spinal Cord; Sulfasalazine; Superoxide Dismutase; Tyrosine

2012
Acetylsalicylic acid and ascorbic acid combination improves cognition; via antioxidant effect or increased expression of NMDARs and nAChRs?
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Ascorbic Acid; Aspirin; Behavior, Animal; Cognition; Deoxyguanosine; Drug Combinations; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Oxidative Stress; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic

2014