aspirin has been researched along with 6-ketoprostaglandin f1 alpha in 267 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 123 (46.07) | 18.7374 |
| 1990's | 98 (36.70) | 18.2507 |
| 2000's | 33 (12.36) | 29.6817 |
| 2010's | 13 (4.87) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawano, K; Kimura, B; Konno, S; Tamura, K; Tohgi, H | 1 |
| Diss, EM; Gabbe, SG; Kniss, DA; Moore, JW | 1 |
| Amore, C; Buczko, W; D'Adamo, MC; De Curtis, A; de Gaetano, G; Donati, MB; Iacoviello, L | 2 |
| Mochizuki, M; Morikawa, H; Ohashi, M; Takashima, M; Yamasaki, M | 1 |
| Bowman, PD; Salzman, J | 1 |
| Giessler, C; Heinroth-Hoffmann, I; Mest, HJ | 1 |
| Castro, M; Gião-T-Rico, JM; Mota-Filipe, H | 1 |
| Ohkubo, H; Ohmuro, S; Taga, F; Tsukada, Y; Uchida, H | 1 |
| de Sèze, O; Doutremepuich, C; Lalanne, MC; Ramboer, I | 1 |
| Axford, T; Feingold, H; Gray, AD; Khabbaz, K; Khuri, SF; Marquardt, C; Ragno, G; Valeri, CR | 1 |
| de la Cruz, JP; Mata, JM; Sanchez de la Cuesta, F | 1 |
| Chiabrando, C; Fanelli, R; Martelli, L; Rivoltella, L; Valzacchi, S | 1 |
| Jáchymová, M; Knotková, V; Nĕmecek, K; Petrů, I | 1 |
| Inoue, M; Kanemaru, Y; Kazama, Y; Noguchi, T; Onaya, T; Tawata, M; Wakasugi, M | 1 |
| Peskar, BA; Peskar, BM; Trautmann, M | 1 |
| Khosseĭn Shakhavat, AF; Shelest, AN; Shushliapin, OI | 1 |
| Cheng, WW; Zhang, ZJ | 1 |
| Keery, RJ; Lumley, P; Watts, IS; Wharton, KA; White, BP | 1 |
| McLeod, LJ; Roberts, MS; Vial, JH | 1 |
| Bhakdi, S; Eberspächer, B; Grimminger, F; Holland, IB; Hugo, F; Obernitz, R; Seeger, W; Suttorn, N; Thomas, M; Walmrath, D | 1 |
| Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S | 1 |
| Benedict, CR; Buja, LM; Campbell, WB; Falinska, B; McNatt, J; Rosolowsky, M; Willerson, JT; Yao, SK | 1 |
| Ladnyĭ, AI; Malaia, LT | 1 |
| Imanishi, M; Miura, K; Okumura, M; Shimmen, T; Yamamoto, K; Yamanaka, S; Yamashita, Y; Yukimura, T | 1 |
| Eldor, A; Goldfarb, A; Lellouche, F; Maclouf, J; Rachmilewitz, EA | 1 |
| Avots-Avotins, A; Bjorkman, DJ; Mitchell, MD; Moore, JG | 1 |
| Belch, JF; Fisher, TC; Forbes, CD; McLaren, M; Saniabadi, AR | 1 |
| Arai, T; Hatano, Y; Komatsu, K; Mori, K; Nakajima, Y; Noda, J; Sawada, M; Shinkura, R | 1 |
| Gréen, K; Vesterqvist, O | 2 |
| Furui, H; Furumichi, T; Hayashi, H; Saito, H; Suzuki, T; Yamada, Y; Yamauchi, K; Yokota, M | 1 |
| McLeod, LJ; Roberts, MS; Seville, PR; Vial, JH | 1 |
| Hamano, S; Ikeda, S; Kikuchi, S; Kojima, M; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y | 1 |
| Brown, CE; Cox, K; Gant, NF; Magness, RR; Rosenfeld, CR; Spitz, B | 1 |
| Mikashima, H; Muramoto, Y | 1 |
| Boncinelli, S; Castellani, S; Chelucci, GL; Cresci, F; Gensini, GF; Linden, M; Lorenzi, P; Marsili, M; Merciai, V; Rostagno, C | 1 |
| Fulton, DR; Meissner, C; Peterson, MB | 1 |
| Begnis, R; Benigni, A; Garattini, S; Livio, M; Morelli, C; Remuzzi, G; Rossini, M; Zoja, C | 1 |
| Kadowitz, PJ; Mayeux, PR; McNamara, DB | 1 |
| Nishikawa, T; Shimizu, S; Tomori, Y; Yamashita, S | 1 |
| Axelrod, L; Lane, J; Parker, J | 1 |
| Inoguchi, T; Kunisaki, M; Nawata, H; Ono, H; Umeda, F; Watanabe, J | 1 |
| Brenner, B; Eichler, HG; Heistinger, M; Kyrle, PA; Lechner, K; Marosi, L; Minar, E | 1 |
| Catella, F; Fitzgerald, GA; Lupinetti, MD; Sheller, JR | 1 |
| Carpenter-Deyo, L; Roth, RA | 1 |
| Chakraborti, S; Gurtner, GH; Michael, JR | 1 |
| Aza, MJ; Castellarnau, C; Collado, PS; Gonzalez, J; Lasierra, J; Melon, J; Rutllant, M; Vazquez, E | 1 |
| Gupta, C | 1 |
| Kobayashi, I; Kusakabe, K; Maruyama, S; Nagayama, T; Shibagaki, Y; Sone, R; Uchiyama, S | 1 |
| Barrow, SE; Beacham, J; Cockcroft, JR; Doktor, HS; Ritter, JM | 1 |
| Ballerini, S; Benigni, A; Chiabrando, C; Fanelli, R; Frusca, T; Gregorini, G; Orisio, S; Piccinelli, A; Pinciroli, V; Valcamonico, A | 1 |
| Joyce, RM; McLeod, LJ; Roberts, MS; Seville, PR; Vial, JH | 1 |
| Docherty, JC; Gerrard, JM; Kobrinsky, NL; Kostolansky, I; McKenzie, JK; McNicol, A; Rowe, R; Singhroy, S; Taback, S | 1 |
| Cronenwett, JL; Huntsman, WT; McDaniel, MD; Miett, TO | 1 |
| FitzGerald, GA; Nowak, J | 1 |
| Barsacchi, R; De Caterina, R; Giannessi, D; Lazzerini, G; Nanni, N; Pelosi, G | 1 |
| Boss, AH; Catella, F; Ciabattoni, G; Daffonchio, L; Daugherty, J; Dray, F; FitzGerald, GA; Patrono, C | 1 |
| Schulz, R; Seeger, W | 1 |
| Brath, PC; Thorp, JA; Walsh, SW | 1 |
| Ciabattoni, G; Cominelli, F; Gentilini, P; La Villa, G; Laffi, G; Mannelli, M; Patrignani, P; Pinzani, M | 1 |
| Fischer, C; Frölich, JC; Meese, CO; Rosenkranz, B | 1 |
| Cerletti, C; de Gaetano, G; Gambino, MC; Garattini, S | 1 |
| Karmazyn, M | 1 |
| Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF | 1 |
| Adkinson, NF; Brown, MS; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Peters, SP; Proud, D | 1 |
| Punzengruber, C; Silberbauer, K; Sinzinger, H | 1 |
| Bucchi, F; Cerletti, C; de Goetano, G; Gambino, MC; Rajtar, G; Riva, E | 1 |
| Bodzenta, A; Bucchi, F; Cerletti, C; de Gaetano, G | 1 |
| Kagawa, K; Kagawa, T; Kasahara, K; Masuda, A; Nonoyama, A; Omoto, K; Sakurai, Y | 1 |
| Cook, JA; Halushka, PV; Smith, EF; Wise, WC | 1 |
| Le Breton, GC; Zaragoza, R | 1 |
| Delvos, U; Janssen, B; Müller-Berghaus, G | 1 |
| Rak, K; Török, I; Udvardy, M | 1 |
| Farquhar, C; Ritter, JM; Rodin, A; Thom, MH | 1 |
| Anderson, WP; Bobik, A | 1 |
| Bucchi, F; Cerletti, C; Chen, ZM; de Gaetano, G; Gambino, MC; Gori, G; Latini, R; Passaghe, S | 1 |
| Alix, JL; Cordonnier, D; Duperray, A; Tranqui, L | 1 |
| Förster, W; Lueddeckens, G; Schaper, U; Scheuch, DW | 1 |
| Hauser, A; Heinroth-Hoffmann, I; Mest, HJ; Taube, C | 1 |
| Heine, H; Misselwitz, F; Norden, C | 1 |
| Friedman, GB; Libby, P; Warner, SJ | 1 |
| Frazer, CE; Ritter, JM | 1 |
| Beckman, J; Klein, RC; Peake, G | 1 |
| Konturek, SJ; Kwiecień, N; Obtułwicz, W; Oleksy, J | 1 |
| Takeuchi, K; Tanaka, H; Ueki, S | 1 |
| Dubois, A; Montcalm, E; Shea-Donohue, T; Steel, L | 1 |
| Barr, RD; Buchanan, MR; Gibson, BE; White, JG | 1 |
| Kameda, K; Kihara, S; Kubo, M; Matsuzawa, Y; Nozaki, S; Tarui, S | 1 |
| Kasdon, E; Marrone, G; Rowe, PH; Silen, W; Starlinger, MJ | 1 |
| Grabowski, EF; Hernandez, Y; Subramanian, VA; Tack-Goldman, K; Weksler, BB | 1 |
| McCauley, FA; Wells, HD; Wilson, TW | 1 |
| Vesterqvist, O | 1 |
| Eisert, WG; Eldor, A; Fuks, Z; Muller, TH; Vlodavsky, I | 1 |
| Eichler, HG; Jäger, U; Kyrle, PA; Lechner, K | 1 |
| de Groot, PG; Kallmann, R; Nieuwenhuis, HK; Sixma, JJ; van Gijn, J | 1 |
| Donovan, DL; Evancho, MM; Hirko, MK; Hunter, TJ; Schmidt, SP; Sharp, WV | 1 |
| Chen, YC; Kuo, TL; Lee, TK | 1 |
| Carey, F; Haworth, D | 1 |
| Ferrier, GR; Karmazyn, M; Moffat, MP | 2 |
| Carriero, MR; Cerletti, C; de Gaetano, G; Mussoni, L | 1 |
| De Caterina, R; de Nes, M; L'Abbate, A; Marzilli, M; Michelassi, C; Simonetti, I | 1 |
| Butler, J; Jindal, SK; Kirk, W; Lakshminarayanan, S | 1 |
| Cerletti, C; Costantini, V; De Amicis, G; de Gaetano, G; Dejana, E; Lorenzi, G | 1 |
| Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
| Hansel, W; Reimers, TJ; Ullmann, MB | 1 |
| Gay, WA; Subramanian, VA; Tack-Goldman, K; Weksler, BB | 1 |
| Ardillo, G; Cerbone, AM; Cianciaruso, B; Cirillo, F; Di Minno, G; Federico, S; Pannain, M; Pecoraro, C; Ungaro, B; Usberti, M | 1 |
| Martin, JG; Powell, WS; Shore, SA | 1 |
| Magness, RR; Mitchell, MD; Osei-Boaten, K; Rosenfeld, CR | 1 |
| Gershlick, AH; Lewis, CT; Mills, PG; Murday, AJ; Syndercombe Court, YD | 1 |
| Toivanen, J; Viinikka, L; Ylikorkala, O | 1 |
| Díez, M; Fernández, A; Gil, M; Lasierra, J; Velázquez, E; Viladés, E | 1 |
| Allen, PD; Dunham, B; Hechtman, HB; Krausz, MM; Mannick, JA; Shepro, D; Utsunomiya, T | 1 |
| Adler, B; Gimbrone, MA; Handin, RI; Schafer, AI | 1 |
| Buchanan, MR; Butt, R; Hirsh, J; Rischke, JA; Rosenfeld, J; Turpie, AG | 1 |
| Kaplan, S; Marcoe, KF; Sauvage, LR; Wu, HD; Zammit, M | 1 |
| Agradi, E; Colombo, C; Folco, GC; Galli, C; Petroni, A; Socini, A; Tremoli, E | 1 |
| Kazmi, GM; Littner, MR; Lott, FD | 1 |
| Aikawa, M; Dunn, M; Hassid, A; Pugliese, F; Sato, M; Williams, S | 1 |
| Colombo, G; Glässer, A; Luzzani, F; Schiatti, P; Selva, D | 1 |
| Hanley, SP; Hughes, J | 1 |
| Viinikka, L; Ylikorkala, O | 1 |
| Gurewich, V; Louie, S | 1 |
| Kauppila, A; Viinikka, L; Ylikorkala, O | 1 |
| Lohsiriwat, S; Malvin, RL | 1 |
| Aguila, E; Lopez, L; Mehta, JL; Mehta, P; Ostrowski, N | 1 |
| Ritter, JM | 1 |
| Ali, M; de Kergommeaux, BD; McDonald, JW | 1 |
| Buchanan, MR; Gimbrone, MA; Vazquez, MJ | 1 |
| Custro, N; Davì, G; Mattina, A; Novo, S; Strano, A | 1 |
| Ali, M; de Kergommeaux, BD; Hayward, CP; McDonald, JW | 1 |
| Inoue, M; Kojima, T; Morikawa, M; Tsuboi, M | 1 |
| Brash, A; Fitzgerald, G; Oates, JA | 1 |
| Chap, H; Douste-Blazy, L; Hullin, F; Thomas, JM | 1 |
| Butler, KD; Maguire, ED; Smith, JR; Turnbull, AA; Wallis, RB; White, AM | 1 |
| Caimi, G; Castello, F; Davì, G; Fazio, M; La Menza, B; Marino, S; Mazzola, A; Novo, S; Romano, A; Valdes, L | 1 |
| Capodicasa, G; Davì, G; Galione, G; Mazzola, A; Meringolo, C; Orlandi, M; Picone, F; Strano, A; Tomasi, V | 1 |
| Clark, KE; Klein, KL; Scott, WJ | 1 |
| Bach, MK; Bothwell, WM; Creese, BR; Fitzpatrick, FA | 1 |
| Ali, M; Cooper, JD; McDonald, JW; Morgan, E; Townsend, ER | 1 |
| Randall, MJ; Wilding, RI | 2 |
| Jones, PB; Russell, RG | 1 |
| Ali, M; Cragg, DB; Forrest, JB; McDonald, JW; Todd, MH | 1 |
| Cook, JA; Halushka, PV; Wise, WC | 2 |
| Dale, J; Myhre, E; Parry, J; Thaulow, E | 1 |
| Davies, JA; Feely, M; Menys, VC; Tindall, H; Tooke, JE | 1 |
| Bott, SJ; Demers, LM; Shaikh, BS | 1 |
| Ingerman-Wojenski, C; Nissenbaum, M; Sedar, AW; Silver, MJ; Smith, JB | 1 |
| De Groot, PG; Gonsalvez, MS; Pool, GA; Van Aken, WG; Van Mourik, JA; Willems, C | 1 |
| Crews, F; Horalek, C; Mehta, J; Mehta, P; Ostrowski, N; Roy, L | 1 |
| Beamish, RE; Dhalla, NS; Karmazyn, M; Moffat, MP | 1 |
| Hensby, CN; Kohner, EM; Lewis, PJ; MacDermot, J; Porta, M; Webster, J | 1 |
| Boyd, J; Eling, T; Korbut, R | 1 |
| Kiistala, U; Oikarinen, A; Rytsälä, H; Viinikka, L; Ylikorkala, O | 1 |
| Dunham, BM; Grindlinger, GA; Hechtman, HB; Krausz, MM; Shepro, D; Utsunomiya, T | 1 |
| Hsu, P; Leffler, CW; Parfenova, H | 1 |
| Copeland, JR; Ellis, EF; Moore, SF; Tynan, TM; Willoughby, KA | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Schröder, EP; Tsikas, D | 1 |
| Gréen, K; Henriksson, P; Rasmanis, G; Vesterqvist, O | 1 |
| Dewit, L; Oussoren, Y; Stewart, FA; Verheij, M; Weening, JJ | 1 |
| Fischlein, T; Fittkau, M; Lante, W; Lehner, G; Murphy, JG; Reichart, B; Weinhold, C | 1 |
| Brandt, L; Pickard, JD; Smythe, J; Walker, V; Zygmunt, S | 1 |
| Bremer, HA; Brommer, EJ; Rotmans, N; Wallenburg, HC | 1 |
| Chang, MC; Huang, TF; Wang, CY | 1 |
| Feldman, M; Lee, M | 1 |
| Drobinski, G; Grosgogeat, Y; Maclouf, J; Montalescot, G; Salloum, J; Thomas, D | 1 |
| Anastasio, P; Borsatti, A; Calò, L; Cantaro, S; Capasso, G; Coppola, S; DeSanto, NG; Favaro, S | 1 |
| Ando, F; Arakawa, M; Kambara, K; Kano, A; Ohno, M; Segawa, T | 1 |
| Luo, Y | 1 |
| Bearn, PE; Bull, H; Marston, A; McCollum, CN; Seddon, AM | 1 |
| Jesse, R; Walsh, SW; Wang, Y | 1 |
| Arruzazabala, ML; Carbajal, D; Más, R; Molina, V; Valdés, S | 1 |
| Adams, KE; Brown, PA; Heys, SD; Whiting, PH | 1 |
| Jin, L; Xu, SH; Yan, XW | 1 |
| Cohen, DS; Dotson, R; Mathis, J; Olson, RW; Webb, RL | 1 |
| Ebbeling, L; Gerrard, JM; Gow, JA | 1 |
| Harada, T; Juhn, SK; Kim, Y; Sakakura, Y | 1 |
| Allegra, A; Boncinelli, S; Chelucci, A; Chelucci, GL; Cresci, F; Linden, M; Lorenzi, P; Marsili, M; Merciai, V; Rostagno, C | 1 |
| Bachir, D; Foulon, I; Galacteros, F; Maclouf, J | 1 |
| Alemany, M; Bastida, E; Bozzo, J; Buchanan, MR; Hernández, R; Ordinas, A | 1 |
| Goto, H; Hayakawa, T; Kanamori, S; Ozawa, T; Shimomura, Y; Sugiyama, S | 1 |
| Allen, KG; Harris, MA; Miller, CW; Norman, JF; Smith, MJ | 1 |
| Chen, Z; Gao, R; Liu, H | 1 |
| Engelhardt, G | 1 |
| Fuse, I; Hattori, A; Mito, M; Ootsuka, T; Shibata, A | 1 |
| Bichile, SK; Deo, AM; Mehta, PJ | 1 |
| Madan, ZM; Sainani, GS | 1 |
| Imura, Y; Nishikawa, K; Terashita, Z | 1 |
| Copeland, JR; Ellis, EF; Police, RJ; Willoughby, KA | 1 |
| Garnier, LF; Mathieu, P; Scheck, F; Stoltz, JF; Villemot, JP | 1 |
| De la Cruz, JP; García Campos, JM; Moreno, A; Muñoz, M; Sánchez de la Cuesta, F | 1 |
| Katori, R; Kawabata, H; Sugiyama, K | 1 |
| Anges, C; Zou, M | 1 |
| Feng, D; Gebara, OC; Lipinska, I; McKenna, C; Mittleman, MA; Muller, JE; Murillo, J; Tofler, GH | 1 |
| Gullichsen, E; Kuttila, K; Mucha, I; Nelimarkka, O; Niinikoski, J; Rautanen, M; Riutta, A | 1 |
| Dial, EJ; Felder, TB; Giraud, MN; Illich, PA; Lichtenberger, LM; Sanduja, SK | 1 |
| Bronson, R; Martin, A; Meydani, M; Meydani, SN; Russell, RM; Smith, D; Stickel, F; Wu, D | 1 |
| Dalsgaard, CJ; Haegerstrand, A; Martinsson, T | 1 |
| Campbell, WB; Deinhart, DD; Pfister, SL | 1 |
| Arakawa, M; Honda, K; Imai, T; Kurabayashi, T; Takakuwa, K; Tamura, M; Tanaka, K | 1 |
| Duffy, SJ; Esler, MD; Harper, RW; Meredith, IT; New, G; Tran, BT; Tudball, RN | 1 |
| Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q | 1 |
| Boylan, PC; Fitzgerald, DJ; FitzGerald, GA; McAdam, BF; McParland, P; Regan, CL | 1 |
| Chen, ZH; Duan, L; Liang, Y; Liu, WP; Shen, ZQ | 1 |
| Andrieu, S; Berdeaux, A; Bévérelli, F; Giudicelli, JF; Lebret, M; Maclouf, J | 1 |
| Chen, ZH; Liu, WP; Ma, GY; Shen, ZQ; Wang, DC; Wu, WL; Xiong, HZ; Yang, YK | 1 |
| Aceituno, E; Casado, S; de Frutos, T; del Pozo, V; Farré, J; García, R; Gómez, J; González-Fernández, F; Jiménez, A; Lahoz, C; López-Farré, A; Millás, I; Rico, L; Sánchez de Miguel, L | 1 |
| Bing, RJ; Cho, YK; Cohen, AM; Johnson, PE; Kakar, NR; Yamamoto, M; Yamamoto, T | 1 |
| Braun-Dullaeus, RC; Feussner, M; Grimminger, F; Haberbosch, W; Hopmann, H; Kraemer, HJ; Tillmanns, H; Walker, G | 1 |
| Chong, ZZ; Feng, YP | 1 |
| Anand, BS; Lichtenberger, LM; Romero, JJ; Sanduja, SK | 1 |
| Guzzo, C; Lazarus, G; Mitchell, TA; Morrow, JD; Oates, JA; Roberts, LJ; Zackert, WE | 1 |
| Bellisola, G; Guidi, GC; Perona, G; Ricetti, MM; Rigo, A; Tecchio, C | 1 |
| Gurbel, PA; Lowry, DR; Murugesan, SR; Serebruany, VL | 1 |
| Laperrière, L; Latour, JG; Libersan, D; Merhi, Y; Quan, E; Uzan, A | 1 |
| Hishinuma, T; Matsumura, E; Mizugaki, M; Murai, Y; Tamai, M; Yamanobe, S; Yamazaki, T | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Olszanecki, R; Uracz, W; Ziemianin, B | 1 |
| Bernareggi, M; Berti, F; Berti, M; Colonna, VD; Del Soldato, P; Rossoni, G | 1 |
| Chiu, CH; McEntee, MF; Whelan, J | 1 |
| Belton, O; Byrne, D; Fitzgerald, DJ; Kearney, D; Leahy, A | 1 |
| Imanishi, M; Katayama, Y; Tsuji, T; Yasu, T | 1 |
| Bing, RJ; Johnson, PE; Kakar, NR; Vina, ER; Yamamoto, T | 2 |
| Haghiac, M; Hilderman, RH; Pojoga, LH | 1 |
| Engström, K; Saldeen, T; Wallin, R | 1 |
| Adderley, SR; Cunningham, AJ; Dowd, NP; Fitzgerald, DJ; Scully, M | 1 |
| Bauer, AK; Dwyer-Nield, LD; Hankin, JA; Malkinson, AM; Murphy, RC | 1 |
| Hong, E; Huang, F; Sun, J; Xiu, Q | 1 |
| de la Cruz, JP; González-Correa, JA; Guerrero, A; Márquez, E; Nacle, I; Sánchez de la Cuesta, F | 1 |
| Arrebola, MM; De La Cruz, JP; Escalante, R; Guerrero, A; Sánchez de La Cuesta, F; Villalobos, MA | 1 |
| Byrne, MF; Cullen, L; Fitzgerald, DJ; Murray, FE; Shah, AA; Walsh, T | 1 |
| Arruzazabala, ML; Carbajal, D; Más, R; Molina, V | 1 |
| Cmiel, A; Mejza, F; Szczeklik, A; Tuleja, E | 1 |
| Capone, ML; Di Gregorio, P; Grana, M; Merciaro, G; Minuz, P; Patrignani, P; Patrono, C; Ricciotti, E; Sciulli, MG; Tacconelli, S | 1 |
| Alcindor, D; Kersten, JR; Krolikowski, JG; Pagel, PS; Warltier, DC | 1 |
| Guth, BD; Narjes, H; Nehmiz, G; Riedel, A; Schubert, HD; Tanswell, P | 1 |
| Buerkle, MA; Conzen, P; Krötz, F; Lehrer, S; Pohl, U; Sohn, HY | 1 |
| Koivisto, AM; Mäenpää, J; Riutta, A; Vainio, M | 1 |
| Hillbom, M; Juvela, S; Pyhtinen, J; Riutta, A; Saloheimo, P | 1 |
| Lacasse-M, S; Larivière, R; Lebel, M; Rodrigue, ME | 1 |
| Birnbaum, Y; Huang, MH; Lin, Y; Lui, CY; Martinez, JD; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Duan, WG; Jiang, ZZ; Liu, DQ; Yan, M; Yao, JC; Yun, Y; Zhang, LY | 1 |
| Kang, KB; Majewski, H; Rajanayagam, MA; van der Zypp, A | 1 |
| Anzellotti, P; Capone, ML; Di Francesco, L; Di Gregorio, P; Merciaro, G; Patrignani, P; Sciulli, MG; Tacconelli, S | 1 |
| Aguejouf, O; Belon, P; Desplat, V; Doutremepuich, C; Eizayaga, FX | 1 |
| Gu, Y; Lewis, DF; Wang, Y; Zhao, S | 1 |
| Chen, P; Duan, WG; He, B; Ma, JQ; Shen, ZQ; Wang, DH; Wang, L; Yang, Y; Yun, Y; Zheng, CL | 1 |
| Asensi, R; Correa, JA; De La Cruz, JP; Espartero, JL; López-Villodres, JA; Rodríguez-Gutiérez, G | 1 |
| Dercho, RA; Di Francesco, A; Di Francesco, L; Dovizio, M; Evangelista, V; Pandolfi, A; Patrignani, P; Piccoli, A; Salvatore, T; Seta, F; Totani, L | 1 |
| Baker, LD; Breitner, JC; Milne, G; Montine, TJ; Sonnen, JA | 1 |
| De la Cruz, JP; Gonzalez-Correa, JA; Jebrouni, N; Lopez-Villodres, JA; Reyes, JJ; Ruiz-Moreno, MI | 1 |
| Chen, SX; Fan, XF; Wang, LX; Wang, MS; Zeng, HH | 1 |
| Hoshina, K; Manita, S; Matsuzawa, S; Miyata, Y; Ooie, T; Sasahara, T; Sueyoshi, S; Yasue, T | 1 |
| Blaha, CA; Drew, RC; Herr, MD; Mast, JL; Muller, MD; Sinoway, LI; Stocker, SD | 1 |
| Barbieri, SS; Cavalca, V; Dragani, A; Pagliaccia, F; Patrono, C; Porro, B; Rocca, B; Squellerio, I; Tremoli, E; Veglia, F | 1 |
| Anand, SS; Chasman, DI; Connolly, SJ; Eikelboom, J; Eriksson, N; Gerstein, HC; Mehta, S; Paré, G; Ridker, PM; Rose, L; Ross, S; Wallentin, L; Yusuf, S | 1 |
| Birnbaum, Y; Kodakandla, M; Ling, S; Nanhwan, MK; Nylander, S; Ye, Y | 1 |
| Blaha, CA; Drew, RC; Herr, MD; Sinoway, LI; Stocker, SD | 1 |
| Kong, XJ; Li, JY; Liu, XW; Ma, N; Mohamed, I; Shen, DS; Yang, YJ; Zhao, XL | 1 |
| Hernandez-Gonzalez, L; López Juan, MG; Majluf-Cruz, A; Martinez, M; Mayoral-Andrade, G; Perez Campos Mayoral, C; Perez-Campos Mayoral, E; Pérez-Campos, E; Pérez-Campos-Mayoral, L; Pérez-Santiago, AD; Rocha-Núñez, A; Zenteno, E | 1 |
| Otsuji, Y; Takahara, K; Yasumasu, T | 1 |
| Kou, N; Miao, Y; Qu, H; Shi, DZ; Wang, MM; Xue, M; Yang, B; Yang, L; Zang, MX | 1 |
| Bian, YY; Wang, LL; Yan, HY; Zou, CC | 1 |
43 trial(s) available for aspirin and 6-ketoprostaglandin f1 alpha
| Article | Year |
|---|---|
[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure].
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Glycosides; Diuretics; Epoprostenol; Heart Failure; Humans; Myocardial Infarction; Nitrates; Piroxicam; Thromboxane A2; Thromboxane B2; Thromboxanes | 1991 |
[Low-dose aspirin preventing pregnancy induced hypertension].
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Double-Blind Method; Female; Fibronectins; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; Thromboxane B2 | 1991 |
Effect of dipyridamole alone and in combination with aspirin on whole blood platelet aggregation, PGI2 generation, and red cell deformability ex vivo in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Dipyridamole; Double-Blind Method; Drug Synergism; Epoprostenol; Erythrocyte Deformability; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests | 1991 |
Selective inhibition of platelet cyclooxygenase with controlled release, low-dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Delayed-Action Preparations; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 1990 |
Thromboxane biosynthesis in allergen-induced bronchospasm. Evidence for platelet activation.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Allergens; Aspirin; Blood Platelets; Bronchial Spasm; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Female; Forced Expiratory Volume; Gas Chromatography-Mass Spectrometry; Humans; Male; Placebos; Platelet Activation; Thromboxane A2; Thromboxane B2 | 1989 |
Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Humans; Infusions, Intravenous; Injections; Male; Prostaglandins; Thromboxane B2; Thromboxanes | 1989 |
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Fetus; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Random Allocation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1989 |
Slow-release aspirin and prostaglandin inhibition.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Delayed-Action Preparations; Humans; Thromboxane B2 | 1986 |
Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprostone; Diuresis; Drug Interactions; Electrolytes; Humans; Platelet Aggregation; Prostaglandins; Prostaglandins E; Random Allocation; Salicylates; Thromboxane B2 | 1986 |
Effects of 1 gram oral or intravenous aspirin on urinary excretion of thromboxane B2 and 6-keto-PGF1 alpha in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Aspirin; Biotransformation; Blood Platelets; Cyclooxygenase Inhibitors; Esterases; Humans; Injections, Intravenous; Kidney; Male; Thromboxane B2 | 1986 |
Absence of differential inhibition of thromboxane A2 and prostacyclin by low and high dose aspirin in coronary artery disease.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Coronary Disease; Electrocardiography; Epoprostenol; Humans; Lactates; Lactic Acid; Male; Middle Aged; Thromboxane A2; Thromboxane B2 | 1987 |
Gastroprotection by sucralfate against acetylsalicylic acid in humans. Role of endogenous prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Clinical Trials as Topic; Dinoprostone; DNA; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Prostaglandins; Prostaglandins E; Sucralfate; Thromboxane B2 | 1987 |
Effects of low-dose aspirin on responses to furosemide.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Body Weight; Eicosanoic Acids; Electrolytes; Female; Furosemide; Humans; Male; Radioimmunoassay; Renin; Thromboxane A2; Time Factors | 1986 |
Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Blood Platelets; Blood Vessels; Double-Blind Method; Epoprostenol; Hemostasis; Humans; Male; Thrombosis; Thromboxane A2; Thromboxane B2 | 1987 |
Effects of low doses of aspirin, 10 mg and 30 mg daily, on bleeding time, thromboxane production and 6-keto-PGF1 alpha excretion in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Function Tests; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors | 1987 |
Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphatases; Aged; Aorta, Abdominal; Aortic Aneurysm; Aspirin; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cardiac Output; Female; Humans; Intraoperative Care; Male; Middle Aged; Myocardial Contraction; Myocardium; Papillary Muscles; Premedication; Pulmonary Wedge Pressure; Thromboxane B2; Thromboxanes | 1981 |
Prostaglandins and endometriosis.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Clinical Trials as Topic; Endometriosis; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Epoprostenol; Female; Humans; Indomethacin; Ovarian Neoplasms; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Blood Platelets; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Thromboxane B2; Thromboxane-A Synthase | 1983 |
Prostacyclin, thromboxane and prostaglandin F2 alpha in suction blister fluid of human skin: effect of systemic aspirin and local glucocorticosteroid treatment.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Betamethasone; Blister; Clobetasol; Dinoprost; Epoprostenol; Exudates and Transudates; Humans; Male; Prostaglandins; Prostaglandins F; Skin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Dinoprostone; Epoprostenol; Exercise; Gas Chromatography-Mass Spectrometry; Humans; Male; Physical Endurance; Physical Fitness; Platelet Aggregation; Thromboxane B2 | 1995 |
Effect of low-dose aspirin during pregnancy on fibrinolytic variables before and after parturition.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Female; Fibrinolysis; Humans; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Postpartum Period; Pregnancy; Tissue Plasminogen Activator | 1995 |
Eicosanoid biosynthesis in patients with stable angina: beneficial effects of very low dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Analysis of Variance; Angina Pectoris; Aspirin; Cardiac Pacing, Artificial; Dose-Response Relationship, Drug; Humans; Lactates; Middle Aged; Physical Exertion; Thromboxanes | 1994 |
[Improvement of prostacyclin-thromboxane A2 balance in patients with acute myocardial infarction by intermittent aspirin].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Male; Middle Aged; Myocardial Infarction; Thromboxane B2 | 1993 |
[The effect of low dose aspirin on the platelet function in patients with acute myocardial infarction].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Blood Platelets; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Function Tests; Thromboxane B2 | 1993 |
The effect of regular and enteric-coated aspirin on bleeding time, thromboxane, and prostacyclin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Bleeding Time; Dosage Forms; Eicosanoids; Epoprostenol; Humans; Male; Middle Aged; Tablets, Enteric-Coated; Thromboxane A2; Thromboxane B2 | 1993 |
[Effects of low dose aspirin on platelet function and prostaglandins metabolism in systemic and coronary circulation in patients with ischemia heart disease].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Coronary Circulation; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxane B2 | 1995 |
[Antiaggregant effect and tolerance of calcium carbasalate administrated immediately after aorto-coronary bypass. Results of a double-blind versus placebo study].
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Analgesics; Antithrombin III; Aspirin; beta-Thromboglobulin; Coronary Artery Bypass; Double-Blind Method; Drug Tolerance; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Malondialdehyde; Middle Aged; Platelet Aggregation; Postoperative Care; Thromboxane B2; Urea | 1996 |
Effect of aspirin dosage and enteric coating on platelet reactivity.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aspirin; Double-Blind Method; Humans; Male; Platelet Aggregation; Tablets, Enteric-Coated | 1997 |
Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Double-Blind Method; Eicosanoids; Female; Fetal Blood; Humans; Pre-Eclampsia; Pregnancy; Thromboxane B2 | 1998 |
Phospholipid association reduces the gastric mucosal toxicity of aspirin in human subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Gastric Mucosa; Humans; Male; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Suspensions | 1999 |
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Epoprostenol; F2-Isoprostanes; Female; Humans; Isoenzymes; Macrophages; Male; Membrane Proteins; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane A2; Thromboxane B2 | 2000 |
Different patterns of renal prostaglandins I2 and E2 in patients with essential hypertension with low to normal or high renin activity.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Dinoprostone; Epoprostenol; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin | 2000 |
Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Drug Interactions; Eicosanoids; Eicosapentaenoic Acid; Fish Oils; Humans; Leukotriene B4; Middle Aged; Thromboxane B2 | 2001 |
Effects of two preparations of 75-mg extended-release aspirin on platelet aggregation, prostanoids and nitric oxide production in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Capsules; Cross-Over Studies; Delayed-Action Preparations; Epoprostenol; Female; Humans; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandins; Single-Blind Method | 2002 |
Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endothelium, Vascular; Fibrinolytic Agents; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Naproxen; Prostaglandin-Endoperoxide Synthases; Sulfones; Thrombin; Thromboxane B2 | 2003 |
Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Cardiotonic Agents; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endothelial Cells; Endothelium, Vascular; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Monocytes; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins I; Thromboxane B2 | 2004 |
Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A2 receptor and synthase inhibitor, in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Platelet Aggregation; Pyridines; Thromboxane A2; Thromboxane-A Synthase | 2004 |
Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Hypertension, Pregnancy-Induced; Longitudinal Studies; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Pregnancy, High-Risk; Prostaglandins; Thromboxane A2; Thromboxane B2 | 2004 |
Human pharmacology of naproxen sodium.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; Lipopolysaccharides; Monocytes; Naproxen; Platelet Aggregation; Thromboxane B2 | 2007 |
Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Drug Therapy, Combination; F2-Isoprostanes; Female; Humans; Male; Naproxen; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome | 2010 |
In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Blood Platelets; Clinical Protocols; Drug Dosage Calculations; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thrombocythemia, Essential; Thromboxane A2 | 2014 |
Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation.
Topics: 6-Ketoprostaglandin F1 alpha; Age Factors; Aspirin; Baroreflex; Blood Pressure; Chemoreceptor Cells; Cyclooxygenase Inhibitors; Female; Healthy Volunteers; Heart Rate; Humans; Lower Extremity; Male; Mechanoreceptors; Mechanotransduction, Cellular; Middle Aged; Muscle Contraction; Muscle, Skeletal; Thromboxane B2 | 2015 |
224 other study(ies) available for aspirin and 6-ketoprostaglandin f1 alpha
| Article | Year |
|---|---|
Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1992 |
Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Aspirin; Chorionic Villi; Epoprostenol; Female; Humans; Karyotyping; Pregnancy; Pregnancy Trimester, First; Thromboxane B2; Thromboxanes; Trophoblasts | 1992 |
Effect of aspirin on the fibrinolytic response in perfused rat hindquarters.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Disease Models, Animal; Endothelium, Vascular; Fibrinolysis; Hindlimb; Ligation; Male; Perfusion; Rats; Tissue Plasminogen Activator; Veins; Venous Insufficiency | 1992 |
[A trial of low-dose aspirin therapy in high-risk pregnancy].
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Calcium; Female; Fetal Death; Fetal Growth Retardation; Humans; Lupus Coagulation Inhibitor; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Thromboxane B2; Treatment Outcome | 1992 |
Independent regulation of prostaglandin production and the stress response in human fibroblasts.
Topics: 6-Ketoprostaglandin F1 alpha; Arsenic; Arsenites; Aspirin; Calcimycin; Cell Line; Cell Survival; Dinoprostone; Heat-Shock Proteins; Humans; Kinetics; Sodium Compounds | 1992 |
Relevance of vasoactive mediators for the blood pressure effects of intravenous arachidonic acid injection in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Pressure; Cyproheptadine; Diterpenes; Ginkgolides; Imidazoles; Injections, Intravenous; Lactones; Male; Naphthalenes; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane B2 | 1992 |
Effect of DL-propranolol on nitric oxide production in perfused rat hindquarters.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arginine; Aspirin; Atropine; Carbachol; Cholic Acids; Endothelium, Vascular; Epoprostenol; Male; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Propranolol; Rats; Rats, Inbred Strains | 1992 |
Protective effect of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on myocardial damage due to coronary occlusion and reperfusion in rabbit.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspartate Aminotransferases; Aspirin; Bridged Bicyclo Compounds; Chemotaxis, Leukocyte; Creatine Kinase; Guinea Pigs; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nicotinic Acids; Platelet Aggregation Inhibitors; Rabbits; Thromboxane B2 | 1992 |
In vitro platelets/endothelial cells interactions in presence of acetylsalicylic acid at various dosages.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Cell Communication; Endothelium, Vascular; Humans; Platelet Aggregation Inhibitors; Radioimmunoassay; von Willebrand Factor | 1992 |
Effect of skin temperature on platelet function in patients undergoing extracorporeal bypass.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Bleeding Time; Blood Platelets; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Male; Middle Aged; Platelet Function Tests; Skin Temperature; Thromboxane B2 | 1992 |
Triflusal vs aspirin on the inhibition of human platelet and vascular cyclooxygenase.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Salicylates; Thromboxane B2 | 1992 |
Urinary excretion of thromboxane and prostacyclin metabolites during chronic low-dose aspirin: evidence for an extrarenal origin of urinary thromboxane B2 and 6-keto-prostaglandin F1 alpha in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Epoprostenol; Humans; Male; Thromboxane B2; Thromboxanes; Urine | 1992 |
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Male; Middle Aged; Proteinuria; Thromboxanes | 1991 |
Vitamin D3 stimulates the production of prostacyclin by vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Calcitriol; Calcium; Cells, Cultured; Epoprostenol; Hydroxycholecalciferols; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Rabbits | 1991 |
Aspirin-like drugs, ethanol-induced rat gastric injury and mucosal eicosanoid release.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Eicosanoids; Ethanol; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A | 1991 |
Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Biphenyl Compounds; Dose-Response Relationship, Drug; Epoprostenol; Heptanoic Acids; Humans; Male; Platelet Aggregation; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane B2 | 1991 |
Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Disease Susceptibility; Female; Humans; Male; Random Allocation; Thrombosis; Thromboxane B2; Time Factors | 1991 |
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Capillary Permeability; Epoprostenol; Escherichia coli; Female; Hemolysin Proteins; Hypertension, Pulmonary; In Vitro Techniques; L-Lactate Dehydrogenase; Lung; Male; Neutrophils; Perfusion; Potassium; Pulmonary Artery; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Respiratory Insufficiency; Sulfonamides; Thromboxane B2; Thromboxanes | 1991 |
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1991 |
Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Circulation; Coronary Disease; Coronary Thrombosis; Dogs; Electricity; Female; Male; Platelet Aggregation; Serotonin; Thromboxane B2 | 1991 |
[Pathogenetic and therapeutic significance of the angioprotective systems in patients with coronary arteriosclerosis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Coronary Artery Disease; Depression, Chemical; Drug Therapy, Combination; Humans; Leukotriene B4; Male; Middle Aged; Quercetin; Stimulation, Chemical; Thromboxane A2 | 1990 |
Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; Femoral Artery; Heart Rate; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney; Male; Platelet Activating Factor; Prostaglandins; Pyridinium Compounds; Renal Circulation; Time Factors; Vasoconstriction | 1991 |
In vivo platelet activation in beta-thalassemia major reflected by increased platelet-thromboxane urinary metabolites.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aspirin; Female; Humans; Male; Platelet Activation; Thalassemia; Thromboxane B2 | 1991 |
Age does not influence acute aspirin-induced gastric mucosal damage.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aging; Aspirin; Dose-Response Relationship, Drug; Duodenum; Gastric Acid; Gastric Mucosa; Gastroscopy; Humans; Intestinal Mucosa; Male; Videotape Recording | 1991 |
Contribution of prostacyclin to D-tubocurarine-induced hypotension in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Pressure; Depression, Chemical; Diphenhydramine; Epoprostenol; Female; Heart Rate; Humans; Hypotension; Lysine; Male; Middle Aged; Stimulation, Chemical; Tubocurarine | 1990 |
Aspirin and prostacyclin synthesis in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Bleeding Time; Epoprostenol; Humans; Methods | 1990 |
Inhibitory effects of endothelial cells and calcium channel blockers on platelet aggregation.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aspirin; Blood Platelets; Bone Marrow Cells; Calcium Channel Blockers; Collagen; Diltiazem; Endothelium, Vascular; Epoprostenol; Fibroblasts; Humans; Nicardipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Verapamil | 1990 |
Effect of a thromboxane A2 synthetase inhibitor (OKY-046.HCl) on airway hyperresponsiveness in guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Airway Resistance; Animals; Antigens; Aspirin; Bronchoalveolar Lavage Fluid; Guinea Pigs; Leukotriene E4; Methacrylates; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Physostigmine; Platelet Activating Factor; Propranolol; Respiratory System; SRS-A; Thromboxane B2; Thromboxane-A Synthase | 1990 |
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Analysis of Variance; Angiotensin II; Aspirin; Blood Pressure; Chi-Square Distribution; Dinoprostone; Eicosanoids; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Pregnancy Trimester, Third; Thromboxane B2 | 1990 |
Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Imidazoles; Male; Rabbits; Shock, Septic; Survival Rate; Thromboxane B2; Thromboxane-A Synthase | 1990 |
The prominent role of thromboxane A2 formation on early pulmonary hypertension induced by oleic acid administration in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Blood Pressure; Disease Models, Animal; Hypertension, Pulmonary; Leukocytes; Oleic Acid; Oleic Acids; Sheep; Thromboxane A2; Vascular Resistance | 1990 |
Effects of current therapy of Kawasaki disease on eicosanoid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Child; Child, Preschool; Drug Therapy, Combination; gamma-Globulins; Humans; Infant; Infusions, Intravenous; Mucocutaneous Lymph Node Syndrome; Prostaglandins E; Thromboxane B2; Time Factors | 1988 |
Differential inhibition by aspirin of platelet thromboxane and renal prostaglandins in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Injections, Intravenous; Kidney; Male; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Evidence for a bidirectional prostaglandin endoperoxide shunt between platelets and the bovine coronary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Coronary Vessels; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Humans; Imidazoles; Intramolecular Oxidoreductases; Isomerases; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Different modes of inhibition of rat gastric mucosal 6-keto-PGF1 alpha production by indomethacin, aspirin and aminopyrine.
Topics: 6-Ketoprostaglandin F1 alpha; Aminopyrine; Animals; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1989 |
Cooperation of adipocytes and endothelial cells required for catecholamine stimulation of PGI2 production by rat adipose tissue.
Topics: 6-Ketoprostaglandin F1 alpha; Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Catecholamines; Cell Communication; Cell Separation; Dose-Response Relationship, Drug; Endothelium, Vascular; Epinephrine; Epoprostenol; Lipolysis; Male; Rats; Rats, Inbred Strains | 1989 |
Abnormality in prostacyclin-stimulatory activity in sera from diabetics.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cells, Cultured; Chromatography, Gel; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dialysis; Endothelium, Vascular; Epoprostenol; Humans; Male; Rats; Rats, Inbred Strains | 1989 |
Thromboxane A2 and prostacyclin generation in the microvasculature of patients with atherosclerosis--effect of low-dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Arteriosclerosis; Aspirin; Bleeding Time; Blood Platelets; Drug Administration Schedule; Endothelium, Vascular; Epoprostenol; Female; Humans; Male; Microcirculation; Middle Aged; Thromboxane A2; Thromboxane B2 | 1989 |
Cyclooxygenase inhibition in lungs or in neutrophils attenuates neutrophil-dependent edema in rat lungs perfused with phorbol myristate acetate.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclooxygenase Inhibitors; Lung; Male; Neutrophils; Oxygen; Pulmonary Edema; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Kinetics; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Pulmonary Artery; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1989 |
Spontaneous atherosclerotic lesions and prostacyclin formation in rabbits: effects of combined dipyridamole and aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arteries; Arteriosclerosis; Aspirin; Dipyridamole; Drug Therapy, Combination; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rabbits | 1989 |
The role of prostaglandins in masculine differentiation: modulation of prostaglandin levels in the differentiating genital tract of the fetal mouse.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyproterone; Cyproterone Acetate; Dinoprostone; Female; Genitalia, Female; Genitalia, Male; Gestational Age; Indomethacin; Male; Mice; Prostaglandins; Sex Differentiation; Testosterone | 1989 |
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aged, 80 and over; Aspirin; beta-Thromboglobulin; Blood Platelets; Brain Ischemia; Cell Survival; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
In vivo measurement of thromboxane B2 and 6-keto-prostaglandin F1 alpha in humans in response to a standardized vascular injury and the influence of aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Sex Characteristics; Smoking; Thromboxane B2; Time Factors | 1989 |
Effect of a selective thromboxane synthase inhibitor on arterial graft patency and platelet deposition in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Arteries; Aspirin; Benzofurans; Blood Platelets; Blood Vessel Prosthesis; Carotid Arteries; Dipyridamole; Dogs; Female; Indium; Polyethylene Terephthalates; Polytetrafluoroethylene; Radioisotopes; Random Allocation; Thromboxane B2; Thromboxane-A Synthase | 1987 |
In vivo formation of prostacyclin and thromboxane A2 at the site of platelet-vascular interaction in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Blood Platelets; Blood Vessels; Epoprostenol; Female; Humans; Male; Thromboxane A2; Thromboxane B2 | 1987 |
Characteristics of thromboxane production by the isolated-perfused rat heart.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Heart; Ibuprofen; In Vitro Techniques; Methacrylates; Myocardium; Perfusion; Rats; Thromboxane B2 | 1987 |
Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Female; Humans; Kidney; Male; Radioimmunoassay; Sulindac; Thromboxane B2 | 1987 |
Release of leukotrienes into the perfusate of calcium-ionophore stimulated rabbit lungs. Influence of 5-lipoxygenase inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Aspirin; Benzoquinones; Blood Pressure; Calcimycin; Dose-Response Relationship, Drug; Epoprostenol; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Perfusion; Pulmonary Artery; Quinones; Rabbits; Secretory Rate; SRS-A | 1986 |
Low-dose aspirin inhibits thromboxane, but not prostacyclin, production by human placental arteries.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Arteries; Aspirin; Epoprostenol; Female; Humans; Placenta; Pregnancy; Thromboxane B2 | 1988 |
Altered renal and platelet arachidonic acid metabolism in cirrhosis.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Creatinine; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Female; Humans; Kidney; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Prostaglandins E; Prostaglandins F; Renin-Angiotensin System; Sulindac; Thromboxane A2; Thromboxane B2 | 1986 |
Biochemical selectivity of oral versus intravenous aspirin in rats. Inhibition by oral aspirin of cyclooxygenase activity in platelets and presystemic but not systemic vessels.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aorta, Abdominal; Aspirin; Blood Platelets; Blood Vessels; Injections, Intravenous; Male; Portal Vein; Prostaglandin-Endoperoxide Synthases; Rats; Thromboxane B2; Vena Cava, Inferior | 1986 |
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Circulation; Coronary Disease; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Ibuprofen; Indomethacin; Male; Myocardial Contraction; Myocardium; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1986 |
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors | 1986 |
Arachidonic acid metabolites during nasal challenge.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Female; Histamine; Humans; Male; Nasal Provocation Tests; Peptide Hydrolases; Premedication; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Rhinitis, Allergic, Seasonal; Sneezing; SRS-A; Thromboxanes | 1987 |
[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angina Pectoris; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Exercise Test; Female; Hemodynamics; Humans; Indomethacin; Male; Middle Aged; Nitroglycerin; Prostaglandins; Prostaglandins E | 1986 |
Comparison of the effects of oral and intravenous aspirin administration on platelet and peripheral vascular cyclo-oxygenase activity: studies in rats and in man.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Biological Availability; Blood Platelets; Blood Vessels; Female; Fibrinolysis; Humans; Injections, Intravenous; Kinetics; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Rats; Thromboxane B2 | 1986 |
Prolongation of rat cardiac allograft survival with arachidonic acid metabolism inhibitor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Graft Survival; Heart Transplantation; Lysine; Male; Methacrylates; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Thromboxane B2; Thromboxanes; Transplantation, Homologous | 1987 |
Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Female; Macrophages; Male; Prostaglandin Endoperoxides; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1987 |
Effect of single-dose aspirin on TXA2 and PGI2 cyclooxygenases in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Epoprostenol; Mice; Osmolar Concentration; Prostaglandin-Endoperoxide Synthases; Thromboxane A2 | 1987 |
Effect of lipopolysaccharides on cultured human endothelial cells. Relationship between tissue factor activity and prostacyclin release.
Topics: 6-Ketoprostaglandin F1 alpha; Adenine; Arachidonic Acid; Arachidonic Acids; Aspirin; Cells, Cultured; Endothelium; Epoprostenol; Humans; L-Lactate Dehydrogenase; Lipopolysaccharides; Thromboplastin; Time Factors; Tritium | 1987 |
Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arteriosclerosis; Aspirin; Diabetes Mellitus; Epoprostenol; Female; Humans; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Thromboxane B2 | 1987 |
Low dose aspirin treatment in late pregnancy differentially inhibits cyclo-oxygenase in maternal platelets.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Fetal Blood; Humans; In Vitro Techniques; Pregnancy; Pregnancy Trimester, Third; Thromboxane B2; Umbilical Arteries | 1987 |
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac | 1987 |
Selectivity of oral aspirin as an inhibitor of platelet vs. vascular cyclooxygenase activity is reduced by portacaval shunt in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Gastric Mucosa; Liver; Male; Portacaval Shunt, Surgical; Rats; Salicylates; Salicylic Acid; Thromboxane B2; Time Factors | 1988 |
Effect of mitomycin C on prostacyclin synthesis by human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Calcimycin; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Thrombin; von Willebrand Factor | 1988 |
Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Lauric Acids; Leukocyte Count; Lipoxygenase; Lipoxygenase Inhibitors; Male; Oximes; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2 | 1988 |
Effects of trapidil and trapidil derivatives on arachidonic acid and prostaglandin endoperoxide analogue U 46619-induced blood pressure changes in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Male; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Thromboxane B2; Trapidil | 1988 |
Individually controlled acetylsalicyclic acid (ASA) in the long-term treatment of patients with arteriosclerosis.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Arteriosclerosis; Aspirin; Biomarkers; Humans; Hydroxyeicosatetraenoic Acids; Malondialdehyde; Platelet Aggregation; Reference Values | 1988 |
Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Cell Division; Cells, Cultured; Dinoprost; Dinoprostone; Growth Inhibitors; Immunologic Techniques; Indomethacin; Interleukin-1; Mitogens; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandins; Prostaglandins E; Prostaglandins F; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Recombinant Proteins | 1988 |
Recovery of prostacyclin synthesis by rabbit aortic endothelium and other tissues after inhibition by aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Aspirin; Cycloheximide; Depression, Chemical; Endothelium; Epidermal Growth Factor; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rabbits; Thromboxane B2 | 1987 |
Endogenous prostaglandins in gastric alkaline response in the rat stomach after damage.
Topics: 16,16-Dimethylprostaglandin E2; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bicarbonates; Cimetidine; Dinoprostone; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Membrane Potentials; Prostaglandins; Prostaglandins E; Rats; Taurocholic Acid | 1986 |
Gastric protection by sucralfate. Role of mucus and prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Aluminum; Animals; Anti-Ulcer Agents; Aspirin; Dinoprost; Dinoprostone; Macaca mulatta; Mucus; Prostaglandins; Prostaglandins E; Prostaglandins F; Stomach Ulcer; Sucralfate | 1986 |
Primary thrombocythaemia in childhood: symptomatic episodes and their relationship to thromboxane A2, 6-keto-PGE1 and 12-hydroxy-eicosatetraenoic acid production: a case report.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Alprostadil; Arachidonate 12-Lipoxygenase; Aspirin; Asthma; Blood Platelets; Child; Eosinophilia; Humans; Hydroxyeicosatetraenoic Acids; Male; Platelet Aggregation; Thrombocytosis; Thromboxane A2 | 1987 |
Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Cholesterol; Dinoprostone; Flushing; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Niceritrol; Nicotinic Acids; Patient Compliance; Prostaglandins; Prostaglandins E | 1987 |
Effect of simulated systemic administration of aspirin, salicylate, and indomethacin on amphibian gastric mucosa.
Topics: 16,16-Dimethylprostaglandin E2; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Dinoprostone; Electrophysiology; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; Indomethacin; Metiamide; Prostaglandins; Prostaglandins E; Prostaglandins F; Rana catesbeiana; Sodium Salicylate; Time Factors | 1986 |
Prostacyclin production by internal mammary artery as a factor in coronary artery bypass grafts.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Coronary Artery Bypass; Dinoprostone; Endothelium; Female; Graft Occlusion, Vascular; Humans; Male; Mammary Arteries; Middle Aged; Preoperative Care; Prostaglandins E; Saphenous Vein; Thoracic Arteries; Time Factors; Transplantation, Autologous | 1986 |
Rapid recovery of in vivo prostacyclin formation after inhibition by aspirin. Evidence from measurements of the major urinary metabolite of prostacyclin by GC-MS.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Prostaglandin Antagonists; Thromboxane B2; Time Factors | 1986 |
Different effects of aspirin, dipyridamole and UD-CG 115 on platelet activation in a model of vascular injury: studies with extracellular matrix covered with endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cattle; Cells, Cultured; Dipyridamole; Endothelium; Epoprostenol; Extracellular Matrix; Humans; Models, Biological; Platelet Aggregation; Pyridazines; Thromboxanes | 1986 |
Endothelial cell seeding improves 4 mm PTFE vascular graft performance in antiplatelet medicated dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dipyridamole; Dogs; Endothelium; Graft Occlusion, Vascular; Graft Survival; Male; Microscopy, Electron; Polytetrafluoroethylene; Vascular Patency | 1987 |
Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Brain Ischemia; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid; Sex Factors; Thromboxane B2 | 1987 |
Thromboxane synthase inhibition: implications for prostaglandin endoperoxide metabolism. II. Testing the 'redirection hypothesis' in an acute intravenous challenge model.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Indoles; Kinetics; Male; Prostaglandin Endoperoxides; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase | 1986 |
A possible role for endogenous prostaglandins in the electrophysiological effects of acetylstrophanthidin on isolated canine ventricular tissues.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arrhythmias, Cardiac; Aspirin; Cardiac Pacing, Artificial; Dogs; Female; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Papillary Muscles; Purkinje Fibers; Strophanthidin; Time Factors; Ventricular Function | 1986 |
Low dose aspirin does not prevent fibrinolytic response to venous occlusion.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Aspirin; Fibrinolysis; Hematocrit; Humans; Isoindoles; Phenylbutyrates; Thrombosis; Thromboxane B2 | 1986 |
Coronary vasodilation by nitrates is not mediated by the prostaglandin system: a quantitative cineangiographic study.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angiography; Aspirin; Blood Pressure; Coronary Angiography; Coronary Circulation; Coronary Vessels; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Motion Pictures; Prostaglandin Antagonists; Prostaglandins; Vasodilation | 1986 |
Regulation of increase in anastomotic blood flow following pulmonary arterial occlusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterial Occlusive Diseases; Arteriovenous Anastomosis; Aspirin; Bronchi; Dogs; Indomethacin; Pulmonary Artery; Regional Blood Flow; Thromboxane B2 | 1985 |
Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Drug Interactions; Female; Humans; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2; Varicose Veins; Veins | 1985 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
Progesterone and prostanoid production by bovine binucleate trophoblastic cells.
Topics: 6-Ketoprostaglandin F1 alpha; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aspirin; Cattle; Cell Nucleus; Cell Separation; Cells, Cultured; Culture Media; Dinoprostone; Female; Gonadotropins; Placenta; Pregnancy; Progesterone; Prostaglandins; Prostaglandins E; Thyrotropin | 1985 |
Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Blood Vessels; Coronary Disease; Epoprostenol; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1985 |
Effects of angiotensin II on plasma ADH, prostaglandin synthesis, and water excretion in normal humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angiotensin II; Aspirin; Blood Pressure; Body Water; Glomerular Filtration Rate; Humans; Kidney; Male; Prostaglandins E; Renal Circulation; Renin; Urine; Vasopressins | 1985 |
Endogenous prostaglandins modulate histamine-induced contraction in canine tracheal smooth muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Chromatography, High Pressure Liquid; Dogs; Epoprostenol; Histamine; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins; Radioimmunoassay; Trachea | 1985 |
In vitro prostacyclin production by ovine uterine and systemic arteries. Effects of angiotensin II.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Arteries; Aspirin; Culture Techniques; Epoprostenol; Female; Mesenteric Arteries; Pregnancy; Saralasin; Uterus | 1985 |
Adverse effects of high dose aspirin on platelet adhesion to experimental autogenous vein grafts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Autoradiography; Carotid Arteries; Dipyridamole; Epoprostenol; Graft Occlusion, Vascular; Jugular Veins; Models, Biological; Platelet Adhesiveness; Rabbits | 1985 |
Differential inhibition of platelet thromboxane and lung prostacyclin production by sulphinpyrazone, acetylsalicylic acid and indomethacin by human tissues in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Humans; In Vitro Techniques; Indomethacin; Lung; Sulfinpyrazone; Thromboxane A2; Thromboxane B2 | 1985 |
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Dinoprost; Dinoprostone; Epoprostenol; Guinea Pigs; Ibuprofen; Indomethacin; Ligation; Male; Ouabain; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Time Factors | 1985 |
[Activity of ticlopidine and lysine acetylsalicylate in experimental atheromatosis. Effects on the production of PGI2].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arteriosclerosis; Aspirin; Diet, Atherogenic; Epoprostenol; Lysine; Male; Platelet Aggregation; Rabbits; Thiophenes; Ticlopidine | 1985 |
Prostacyclin and beta-adrenergic catecholamines inhibit arachidonate release and PGI2 synthesis by vascular endothelium.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Arachidonic Acids; Aspirin; Catecholamines; Cattle; Endothelium; Epoprostenol; Gallic Acid; Isoproterenol; Propranolol; Prostaglandins; Prostaglandins F | 1981 |
The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aorta, Thoracic; Aspirin; beta-Thromboglobulin; Blood Platelets; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Endothelium; Epoprostenol; Female; Half-Life; Humans; Kinetics; Male; Platelet Aggregation; Rabbits; Sex Factors; Thromboxane B2 | 1983 |
Aspirin therapy in small-caliber arterial prostheses: long-term experimental observations.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Antigens; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dogs; Epoprostenol; Factor VIII; Malondialdehyde; Platelet Aggregation; Polyethylene Terephthalates; Thromboxane A2; Thromboxane B2; Time Factors; von Willebrand Factor | 1984 |
Platelet-vessel wall interactions: effects of platelets and plasma on the antiaggregatory activity and 6 keto-PGF1 alpha production in isolated perfused aortas.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Blood Platelets; Cyclic AMP; Epoprostenol; In Vitro Techniques; Male; Perfusion; Plasma; Platelet Aggregation; Rats | 1981 |
The effects of arachidonic acid, PGI2, and 6-keto-PGF1 alpha on cyclic nucleotide concentrations in a ventilated and artificially perfused isolated dog lung.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclic AMP; Cyclic GMP; Dogs; Epoprostenol; In Vitro Techniques; Indomethacin; Kinetics; Lung; Perfusion; Prostaglandins; Tranylcypromine | 1982 |
Rabbit and rat renal papillary collecting tubule cells in culture: the interactions of arginine vasopressin, prostaglandins, and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Aspirin; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprost; Dinoprostone; Kidney Tubules; Kinetics; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Rats | 1983 |
Inhibition of PG production by MDL 035, a new non-steroidal non-acidic anti-inflammatory compound, in rat gastric mucosa and inflammatory exudate.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Exudates and Transudates; Gastric Mucosa; Imidazoles; In Vitro Techniques; Indomethacin; Inflammation; Male; Naproxen; Prostaglandins; Prostaglandins E; Rats; Stomach Ulcer | 1984 |
Failure of salicylate to reduce inhibition of human venous prostacyclin in synthesis by conventional dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Epoprostenol; Humans; Kinetics; Prostaglandins; Salicylates; Salicylic Acid; Veins | 1983 |
The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dipyridamole; Epoprostenol; Fibrinolytic Agents; Male; Prostaglandins; Rabbits; Thrombosis; Thromboxanes | 1983 |
Prostaglandin biosynthesis does not participate in isoproterenol-induced renin release.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Dinoprostone; In Vitro Techniques; Isoproterenol; Kidney Cortex; Male; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Renin; Time Factors | 1984 |
Platelet function and biosynthesis of prostacyclin and thromboxane A2 in whole blood after aspirin administration in human subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Humans; Male; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1984 |
Prostanoid synthesis by aortic rings in human blood: selective increase of prostacyclin mediated by a serum factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Citrates; Epoprostenol; Humans; In Vitro Techniques; Male; Methacrylates; Muscle, Smooth, Vascular; Prostaglandins; Radioimmunoassay; Rats; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; In Vitro Techniques; Prostaglandins; Pulmonary Artery; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors | 1983 |
Arachidonic acid metabolism and the adhesion of human polymorphonuclear leukocytes to cultured vascular endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Adhesion; Cells, Cultured; Endothelium; Humans; Lipoxygenase; Neutrophils; Prostaglandin-Endoperoxide Synthases | 1983 |
The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Coagulation; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Male; Thromboxane B2; Thromboxanes; Time Factors | 1983 |
Sensitivity of rabbit platelet and aortic cyclooxygenase to inhibition by aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Female; In Vitro Techniques; Rabbits; Thrombosis; Thromboxane B2 | 1983 |
Sex difference in the inhibitory effect of aspirin on prostacyclin production of rat aortae.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Castration; Epoprostenol; Estradiol; Female; Gonadal Steroid Hormones; Male; Rats; Rats, Inbred Strains; Sex Characteristics; Testosterone | 1984 |
Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Oxidoreductases; Pyridines; Thromboxane-A Synthase; Time Factors | 1984 |
Evidence for a two-step process in prostaglandin secretion. Intracellular accumulation of prostacyclin precedes its release from human endothelial cells in culture.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Cells, Cultured; Endothelium; Epoprostenol; Humans; Thrombin; Umbilical Veins | 1984 |
Prolongation of rat tail bleeding time caused by oral doses of a thromboxane synthetase inhibitor which have little effect on platelet aggregation.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Arthus Reaction; Aspirin; Bleeding Time; Blood Coagulation; Collagen; Dose-Response Relationship, Drug; Fibrin; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Platelet Count; Rabbits; Rats; Rats, Inbred Strains; Tail; Thromboxane-A Synthase | 1982 |
Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Physical Exertion; Platelet Aggregation; Smoking; Thromboxane B2 | 1984 |
Development of a GC-MS method for quantitation of 2,3-dinor-6-keto-PGF1 alpha and determination of the urinary excretion rates in healthy humans under normal conditions and following drugs.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents; Aspirin; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Male; Middle Aged; Physical Exertion | 1984 |
Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Charcoal; Hemoperfusion; Heparin; Humans; Kidney Failure, Chronic; Middle Aged; Platelet Count; Thromboxane B2; Thromboxanes | 1983 |
Prostaglandin synthesis in rat embryo tissue: the effect of non-steroidal anti-inflammatory drugs in vivo and ex vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Aspirin; Dinoprost; Embryo, Mammalian; Female; Indomethacin; Pregnancy; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth; Prostaglandins F; SRS-A; Thromboxane A2; Thromboxanes | 1984 |
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Complement Activation; Female; Hypertension, Pulmonary; In Vitro Techniques; Leukocytes; Lung; Male; Pulmonary Artery; Sheep; Thrombocytopenia; Thromboxane B2; Thromboxanes | 1983 |
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01).
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Electric Stimulation; Imidazoles; Indium; Male; Oxidoreductases; Rabbits; Radioisotopes; Thrombosis; Thromboxane B2; Thromboxane-A Synthase | 1983 |
Effect of aspirin on urinary excretion of 6-ketoprostaglandin F1 alpha.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Dose-Response Relationship, Drug; Humans; Male; Time Factors | 1983 |
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia, General; Animals; Aspirin; Hypotension; Indomethacin; Lung; Male; Perfusion; Pressure; Pulmonary Artery; Pulmonary Embolism; Rabbits; Thromboxane B2; Thromboxanes | 1983 |
Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Fibrin Fibrinogen Degradation Products; Macrophages; Male; Radioimmunoassay; Rats; Shock, Septic; Thromboxane B2 | 1983 |
Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Epoprostenol; Humans; Hyperemia; Male; Prostaglandins; Thromboxane B2 | 1982 |
The differential inhibition of prostaglandin synthesis in platelets and vascular tissue in response to aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Blood Platelets; Ethylmaleimide; Male; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats | 1980 |
Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Ear; Endothelium; Epoprostenol; Male; Prostaglandins; Prostaglandins F; Rabbits; Thromboxane B2 | 1981 |
Arachidonate metabolism in cultured human vascular endothelial cells. Evidence for two prostaglandin synthetic pathways sensitive to acetylsalicylic acid.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cells, Cultured; Cycloheximide; Endothelium; Female; Humans; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Umbilical Veins | 1982 |
Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Epoprostenol; Humans; Methacrylates; Models, Biological; Prostaglandins; Specimen Handling; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Umbilical Veins | 1982 |
Protective effects of aspirin in endotoxic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Glucose; Fibrin Fibrinogen Degradation Products; Lysosomes; Male; Platelet Aggregation; Prostaglandins F; Rats; Shock, Septic; Thromboxane B2 | 1981 |
Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Urea Nitrogen; Creatine Kinase; Isoproterenol; Male; Myocardial Infarction; Prostaglandins F; Rats; Sulfinpyrazone; Thromboxane B2 | 1981 |
Forearm ischaemia as a test of prostacyclin production: studies in normal subjects and in patients with diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Glucose; Diabetic Retinopathy; Forearm; Gas Chromatography-Mass Spectrometry; Hemoglobin A; Humans; Ischemia; Male; Middle Aged; Prostaglandins F | 1981 |
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01).
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Aspirin; Carotid Artery Thrombosis; Cells, Cultured; Enzyme Inhibitors; Fibrinolytic Agents; Imidazoles; In Vitro Techniques; Oxidoreductases; Platelet Aggregation; Rabbits; Thromboxane B2; Thromboxane-A Synthase | 1982 |
Respiratory movements alter the generation of prostacyclin and thromboxane A2 in isolated rat lungs: the influence of arachidonic acid-pathway inhibitors on the ratio between pulmonary prostacyclin and thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Epoprostenol; Fatty Acids; Hyperventilation; Indomethacin; Lung; Male; Prostaglandins; Prostaglandins F; Rats; Thromboxane A2; Thromboxanes; Tranylcypromine | 1981 |
Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dogs; Female; Hemodynamics; Imidazoles; Indomethacin; Male; Myocardial Contraction; Positive-Pressure Respiration; Prostaglandins; Thromboxane B2 | 1981 |
Prostacyclin is required for t-PA release after venous occlusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Fibrinolysis; Iloprost; Imidazoles; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Thromboxane-A Synthase; Tissue Plasminogen Activator; Vena Cava, Inferior | 1994 |
Dilator prostanoid-induced cyclic AMP formation and release by cerebral microvascular smooth muscle cells: inhibition by indomethacin.
Topics: 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Animals, Newborn; Aspirin; Brain; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Enzyme Activation; Iloprost; In Vitro Techniques; Indomethacin; Microcirculation; Muscle, Smooth, Vascular; Receptors, Epoprostenol; Receptors, Prostaglandin; Signal Transduction; Swine | 1995 |
Endothelial and nonendothelial cyclooxygenase mediate rabbit pial arteriole dilation by bradykinin.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Aspirin; Blood Pressure; Bradykinin; Cerebral Arteries; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dinoprostone; Endothelium, Vascular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Rabbits; Vasodilation | 1995 |
Implications of the prognostic importance of exercise-induced thromboxane formation in survivors of an acute myocardial infarction.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Epoprostenol; Exercise; Exercise Test; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Thromboxane A2; Thromboxane B2 | 1995 |
Amelioration of radiation nephropathy by acetylsalicylic acid.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Female; Kidney Diseases; Kidney Function Tests; Mice; Mice, Inbred C3H; Radiation Injuries, Experimental; Rats; Thromboxane B2; X-Rays | 1995 |
Endothelialization of cardiac valve bioprostheses.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Cattle; Cell Division; Cell Transplantation; Endothelial Growth Factors; Endothelium, Vascular; Epoprostenol; Fibroblast Growth Factor 2; Fibronectins; Glutaral; Heart Valve Prosthesis; Heparin; Humans; Microscopy, Electron, Scanning; Radioimmunoassay; Tissue Preservation | 1994 |
Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Brain Damage, Chronic; Cerebral Ventricles; Dexamethasone; Dinoprost; Dinoprostone; Drug Therapy, Combination; Eicosanoids; Humans; Infusions, Intravenous; Intracranial Aneurysm; Nimodipine; Prognosis; Recurrence; Reference Values; Subarachnoid Hemorrhage; Thromboxane B2 | 1994 |
Ancrod-formed fibrin stimulates prostacyclin production of human umbilical vein endothelial cells via de novo synthesis of cyclooxygenase.
Topics: 6-Ketoprostaglandin F1 alpha; Ancrod; Aspirin; Blotting, Western; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Epoprostenol; Fibrin; Humans; Kinetics; Oligopeptides; Prostaglandin-Endoperoxide Synthases; Umbilical Veins | 1994 |
Age-related reductions in gastric mucosal prostaglandin levels increase susceptibility to aspirin-induced injury in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Analysis of Variance; Animals; Aspirin; Dinoprost; Dinoprostone; Gastric Mucosa; Leukotrienes; Male; Prostaglandins; Rats; Rats, Inbred F344 | 1994 |
Renal synthesis of prostaglandins and thromboxane has no causative role for protein-induced glomerular hyperfiltration in healthy humans.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Aspirin; Dietary Proteins; Dinoprostone; Eating; Female; Glomerular Filtration Rate; Humans; Injections, Intravenous; Kidney; Kidney Glomerulus; Meat; Prostaglandins; Thromboxane A2; Time Factors | 1994 |
Effects of acetylsalicylic acid on pulmonary vascular tone and membrane permeability in blood-perfused dog lung.
Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Aspirin; Blood Pressure; Capillary Permeability; Dogs; Extravascular Lung Water; Female; Leukotrienes; Male; Muscle, Smooth, Vascular; Organ Size; Perfusion; Pulmonary Circulation; Salicylates; Salicylic Acid; Thromboxane B2; Vascular Resistance | 1993 |
The effect of platelet inhibitory therapy on graft thromboresistance.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusion, Vascular; Pyridines; Radiography; Random Allocation; Thromboxane-A Synthase | 1993 |
Peroxide induces vasoconstriction in the human placenta by stimulating thromboxane.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Aspirin; Female; Humans; Organ Culture Techniques; Oxidants; Peroxides; Placenta; Pregnancy; tert-Butylhydroperoxide; Thromboxane B2; Vasoconstriction | 1993 |
Effect of policosanol on cerebral ischemia in Mongolian gerbils: role of prostacyclin and thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Brain Ischemia; Drug Synergism; Epoprostenol; Fatty Alcohols; Gerbillinae; Thromboxane A2; Thromboxane B2 | 1993 |
Alleviation of experimental cyclosporin A nephrotoxicity by low dose aspirin in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Creatinine; Cyclosporine; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Thromboxane A2; Urea | 1993 |
Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Caprylates; Coronary Circulation; Coronary Thrombosis; Dinoprostone; Dogs; Hemodynamics; Indoles; Male; Myocardial Reperfusion; Phenylacetates; Platelet Activation; Platelet Aggregation Inhibitors; Pyridines; Receptors, Thromboxane; Streptokinase; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1993 |
Arachidonic acid metabolism by isolated and cultured middle ear epithelial cells from the chinchilla.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Cell Separation; Cells, Cultured; Chinchilla; Dinoprost; Dinoprostone; Ear, Middle; Epithelial Cells; Epithelium; Indomethacin; Prostaglandin D2; Thromboxane B2; Time Factors; Tritium | 1993 |
Aspirin effect on early and late changes in acute lung injury in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Aspirin; Blood Gas Analysis; Hemodynamics; Least-Squares Analysis; Lung; Lung Diseases; Oleic Acid; Oleic Acids; Premedication; Pulmonary Gas Exchange; Respiration; Sheep; Thromboxane B2 | 1993 |
Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Anemia, Sickle Cell; Aspirin; Blood Platelets; Female; Humans; Male; Phosphorylation; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2; Thromboxane B2 | 1993 |
Platelet adhesivity to subendothelium is influenced by polymorphonuclear leukocytes: studies with aspirin and salicylate.
Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Aspirin; Blood Platelets; Cell Communication; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; Lipoxygenase Inhibitors; Neutrophils; Platelet Adhesiveness; Rabbits; Salicylates; Salicylic Acid; Thromboxane B2 | 1993 |
Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa.
Topics: 1,2-Dimethylhydrazine; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Carcinogens; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Dinoprostone; Galactans; Injections, Subcutaneous; Intestinal Mucosa; Male; Mannans; Plant Gums; Prostaglandin D2; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 1995 |
Low-dose aspirin does not attenuate platelet aggregation or atherosclerosis in miniature swine but decreases production of aortic wall prostacyclin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arteriosclerosis; Aspirin; Azo Compounds; Coloring Agents; Coronary Vessels; Epoprostenol; Female; Hypercholesterolemia; Male; Platelet Aggregation; Swine; Swine, Miniature | 1995 |
Effect of acetylsalicylic acid, paracetamol, caffeine and a combination of these substances on the renal prostaglandin E2, 6-keto-prostaglandin F1 alpha, water, creatinine and electrolyte excretion of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Body Water; Caffeine; Central Nervous System Stimulants; Creatinine; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electrolytes; Female; Kidney; Rats; Rats, Inbred Strains | 1996 |
Vascular thromboxane formation in hemostasis mechanism: correlation between bleeding time and vascular TXB2 in a patient with congenital platelet cyclo-oxygenase deficiency.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Arteries; Aspirin; Bleeding Time; Blood Platelets; Bone Marrow; Cyclooxygenase Inhibitors; Endothelium, Vascular; Epoprostenol; Female; Fibroblasts; Hemorrhagic Disorders; Humans; Isoenzymes; Monocytes; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thromboxane B2; Uterus | 1996 |
More uses of known drugs.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Cyclooxygenase Inhibitors; Humans; Myocardial Infarction; Thromboxane B2 | 1995 |
Effect of aspirin treatment on plasma levels of keto PGF 1 alpha and thromboxane B2.
Topics: 6-Ketoprostaglandin F1 alpha; Arrhythmias, Cardiac; Aspirin; Case-Control Studies; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Humans; Myocardial Infarction; Postoperative Care; Thromboxane B2; Time Factors | 1995 |
Inhibition of arachidonic acid induced-aggregation of rabbit platelets with CV-4151 (isbogrel), a selective thromboxane A2 (TXA2) synthase inhibitor: modulation of the antiplatelet action and prostanoid metabolism by rat aortic rings.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Aspirin; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Epoprostenol; Fatty Acids, Monounsaturated; In Vitro Techniques; Intramolecular Oxidoreductases; Isomerases; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane-A Synthase | 1996 |
Repeated cocaine administration reduces bradykinin-induced dilation of pial arterioles.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Alanine Transaminase; Animals; Arterioles; Asphyxia; Aspirin; Bradykinin; Cocaine; Corticosterone; Cyclooxygenase Inhibitors; Male; Pia Mater; Rabbits; Vasodilation; Vasodilator Agents | 1996 |
Effect of aspirin plus dipyridamole on the retinal vascular pattern in experimental diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Diabetes Mellitus, Experimental; Dipyridamole; Epoprostenol; Male; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Retina; Streptozocin | 1997 |
Effect of acetylsalicylic acid on metabolism and contractility in the ischemic reperfused heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Animals; Aspirin; C-Reactive Protein; Coronary Vessels; Energy Metabolism; Heart; Hydrogen-Ion Concentration; Muscle Contraction; Muscle Fibers, Skeletal; Myocardial Ischemia; Perfusion; Phosphates; Platelet Aggregation Inhibitors; Rabbits; Reperfusion Injury; Ventricular Function, Left; Ventricular Pressure | 1996 |
Cell-cell interaction between platelets and IL-1 beta-stimulated vascular smooth muscle cells in synthesis of thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Communication; Cells, Cultured; Coculture Techniques; Cycloheximide; Dactinomycin; Humans; Interleukin-1; Muscle, Smooth, Vascular; Phospholipids; Prostaglandin Endoperoxides; Prostaglandin H2; Prostaglandins H; Rats; Recombinant Proteins; Thrombin; Thromboxane A2 | 1997 |
Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclooxygenase Inhibitors; Embolism, Fat; Epoprostenol; Evaluation Studies as Topic; Hemodynamics; Hypertension, Pulmonary; Lung Diseases; Random Allocation; Swine; Thromboxane A2; Thromboxane B2 | 1997 |
Effect of omeprazole on the bioavailability of unmodified and phospholipid-complexed aspirin in rats.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Drug Carriers; Enzyme Inhibitors; Gastric Mucosa; Male; Neutralization Tests; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley | 1997 |
Effect of vitamin E supplementation on prostaglandin concentrations in aspirin-induced acute gastric injury in aged rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Aging; Animals; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vitamin E | 1997 |
Effects of ropivacaine on eicosanoid release from human granulocytes and endothelial cells in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Eicosanoids; Endothelium, Vascular; Granulocytes; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lidocaine; Mesalamine; Ropivacaine; Thrombin; Zymosan | 1997 |
Methacholine-induced contraction of rabbit pulmonary artery: role of platelet-endothelial transcellular thromboxane synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Endothelium, Vascular; In Vitro Techniques; Male; Methacholine Chloride; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Pulmonary Artery; Rabbits; Thromboxane A2; Vasoconstriction | 1998 |
Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio.
Topics: 6-Ketoprostaglandin F1 alpha; Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Drugs, Chinese Herbal; Female; Humans; Immunosuppressive Agents; Prednisolone; Pregnancy; Thromboxane B2 | 1997 |
Continuous release of vasodilator prostanoids contributes to regulation of resting forearm blood flow in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Adult; Aspirin; Dose-Response Relationship, Drug; Female; Forearm; Humans; Male; Nitroprusside; Norepinephrine; Oxygen Consumption; Prostaglandins; Regional Blood Flow; Rest; Salicylates; Salicylic Acid; Time Factors; Vasodilation | 1998 |
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2 | 1998 |
Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Copper; Drug Combinations; Female; In Vitro Techniques; Intubation, Gastrointestinal; Male; Mice; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Radioimmunoassay; Random Allocation; Thrombosis; Thromboxane B2 | 1998 |
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dogs; Dose-Response Relationship, Drug; Hyperemia; Male; Myocardium; Nitric Oxide Synthase; Nitroarginine; Salicylic Acid; Thromboxane B2; Time Factors | 1999 |
Inhibitory effects of copper-aspirin complex on platelet aggregation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Female; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Serotonin; Thromboxane B2 | 1997 |
Aspirin inhibits inducible nitric oxide synthase expression and tumour necrosis factor-alpha release by cultured smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cardiovascular Diseases; Cattle; Cells, Cultured; DNA-Binding Proteins; Epoprostenol; Gene Expression Regulation; Interleukin-1; Muscle, Smooth; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tumor Necrosis Factor-alpha | 1999 |
Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Vessels; Enzyme Activation; Epoprostenol; Heart; Myocardial Infarction; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandins; Rabbits; Thromboxane A2; Thromboxane B2 | 1999 |
Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Cyclooxygenase Inhibitors; Cyclosporine; Endothelium, Vascular; Heart; Heart Rate; Immunosuppressive Agents; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitric Oxide Donors; Nitroglycerin; Pharmaceutical Vehicles; Polyethylene Glycols; Prostanoic Acids; Rats; Rats, Wistar; Receptors, Thromboxane; Thromboxane B2; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Benzofurans; Brain; Ischemic Attack, Transient; Neuroprotective Agents; Rats; Reperfusion Injury; Thromboxane B2 | 1997 |
Increased formation of thromboxane in vivo in humans with mastocytosis.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; beta-Thromboglobulin; Cyclooxygenase Inhibitors; Female; Humans; Male; Methylhistamines; Middle Aged; Platelet Factor 4; Prostaglandins D; Thromboxane B2; Urticaria Pigmentosa | 1999 |
Effects of sodium selenite on in vitro interactions between platelets and endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aspirin; Blood Platelets; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Activation; Glutathione Peroxidase; Humans; Nitric Oxide; Platelet Aggregation; Selenium; Sodium Selenite; Thromboxane A2; Thromboxane B2 | 1999 |
Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Myocardial Infarction; Reference Values; Thromboxane B2 | 1999 |
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.
Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Aspirin; Blood Cell Count; Cell Movement; Coronary Disease; Dogs; Female; Infarction; Infusions, Intravenous; Male; Malondialdehyde; Neutrophils; Platelet Aggregation; Reperfusion Injury | 1999 |
Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Dose-Response Relationship, Drug; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Pilot Projects; Prostaglandins F; Retinal Artery Occlusion; Retinal Vein Occlusion; Thromboxane A2; Thromboxane B2; Thromboxanes | 1999 |
Thienopyridines: effects on cultured endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Calcimycin; Calcium; Cattle; Cell Line; Cell Survival; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Epoprostenol; Humans; Nitrites; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Time Factors; Umbilical Veins | 1999 |
Myocardial protection by the nitroderivative of aspirin, NCX 4016: in vitro and in vivo experiments in the rabbit.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Aspirin; Creatine Kinase; Dose-Response Relationship, Drug; Electrocardiography; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Peroxidase; Rabbits; Vasoconstrictor Agents; Ventricular Function, Left | 2000 |
Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+)mice.
Topics: 6-Ketoprostaglandin F1 alpha; Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Aspirin; Body Weight; Dinoprostone; Eating; Indomethacin; Intestinal Mucosa; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Prostaglandin Antagonists | 2000 |
The effect of aspirin and two nitric oxide donors on the infarcted heart in situ.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclooxygenase Inhibitors; Drug Interactions; Enzyme Activation; Heart Rate; Male; Myocardial Infarction; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rabbits; Thromboxane A2; Triazenes; Ventricular Pressure | 2000 |
Studies on the effect of diadenlyated nucleotides on calcium mobilization and prostacyclin synthesis in bovine aortic endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Calcium; Cardiovascular Agents; Cattle; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Fluorescent Dyes; Indomethacin; Nitric Oxide; Spectrometry, Fluorescence; Time Factors; Vasodilator Agents; Xanthenes | 2001 |
Effect of cyclooxygenase-2 inhibitor (celecoxib) on the infarcted heart in situ.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Heart; Isoenzymes; Male; Myocardial Infarction; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Sulfonamides; Thromboxane A2 | 2001 |
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonic Acid; Aspirin; Biomarkers; Cardiomyopathies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Doxorubicin; Enzyme Induction; Epoprostenol; Heart; Iloprost; Isoenzymes; L-Lactate Dehydrogenase; Male; Membrane Proteins; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thromboxane B2; Transcription Factors; Troponin T | 2001 |
The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Bronchoalveolar Lavage Fluid; Butylated Hydroxytoluene; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Immunoblotting; Immunoenzyme Techniques; Immunohistochemistry; Isoenzymes; Lung; Lung Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Pneumonia; Prostaglandin-Endoperoxide Synthases; Statistics, Nonparametric | 2001 |
Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Abdominal; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Male; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Prothrombin Time; Radioimmunoassay; Rats; Rats, Wistar; Shikimic Acid; Thrombin Time; Thrombosis; Thromboxane B2 | 2002 |
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Blood Platelets; Chlorobenzenes; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 2002 |
Effect of H. pylori infection on the expression of cyclooxygenase-2 in human gastric mucosa.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Cyclooxygenase 2; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides | 2003 |
Synergistic effect of D-003 and aspirin on experimental thrombosis models.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Death, Sudden; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fatty Acids; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane B2 | 2003 |
Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anesthetics, Inhalation; Animals; Aspirin; Celecoxib; Coronary Circulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diazoxide; Dogs; Hemodynamics; Ischemic Preconditioning, Myocardial; Isoenzymes; Isoflurane; Membrane Proteins; Myocardial Infarction; Myocardium; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2004 |
Selective inhibition of cyclooxygenase-2 enhances platelet adhesion in hamster arterioles in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Arterioles; Aspirin; Cells, Cultured; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelial Cells; Endothelium, Vascular; Humans; Iloprost; Membrane Proteins; Mesocricetus; Nitrobenzenes; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Skin Window Technique; Sulfonamides; Thrombophilia; Umbilical Veins | 2004 |
Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Aged; Aspirin; Bleeding Time; Blood Coagulation; Cerebral Hemorrhage; Epoprostenol; Female; Humans; Male; Middle Aged; Prospective Studies; Regression Analysis; Thromboxane A2; Thromboxane B2 | 2005 |
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelin-1; Epoprostenol; Erythropoietin; Humans; Hypertension; Kidney Cortex; Kidney Function Tests; Male; Mesenteric Arteries; Rats; Rats, Wistar; Recombinant Proteins; Thromboxane B2; Uremia | 2005 |
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Atorvastatin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Membrane Proteins; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley | 2007 |
Screening method for nonsteroidal antiinflammatory drugs based on the cyclooxygenase 2 pathway activated by serum-free stimulation in A549 cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Culture Media, Serum-Free; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Immunoenzyme Techniques; Nitrobenzenes; Pyrazoles; Sulfonamides; Tumor Cells, Cultured | 2007 |
A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Aorta, Thoracic; Aspirin; Immunohistochemistry; Indomethacin; Isoproterenol; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasodilation | 2007 |
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Portal; Lasers; Leukotriene B4; Male; Nitrobenzenes; Platelet Activation; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thrombosis; Thromboxane B2 | 2007 |
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Aspirin; Epoprostenol; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Trophoblasts; Vasoconstriction | 2008 |
Copper-aspirin complex inhibits cyclooxygenase-2 more selectively than aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Copper; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Endothelial Cells; Humans; Macrophages; Mice; Mice, Inbred ICR | 2007 |
Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid.
Topics: 6-Ketoprostaglandin F1 alpha; Acetates; Adult; Aspirin; Blood Platelets; Catechols; Dose-Response Relationship, Drug; Female; Humans; Leukocytes; Male; Nitric Oxide; Olive Oil; Phenylethyl Alcohol; Plant Oils; Platelet Aggregation; Thromboxane B2 | 2009 |
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Atherosclerosis; Benzofurans; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Endothelial Cells; Epoprostenol; Heme Oxygenase-1; Humans; Inflammation; Nitrobenzenes; Perfusion; Propionates; Prostaglandin D2; Receptors, Epoprostenol; Receptors, Prostaglandin; Stress, Mechanical; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Humans; Ibuprofen; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 2010 |
[Effect of aspirin on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Carotid Arteries; Epoprostenol; Hypercapnia; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 2003 |
Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Drug Therapy, Combination; Gastric Mucosa; Guinea Pigs; Immunoenzyme Techniques; Indicators and Reagents; Male; Mice; Phosphodiesterase Inhibitors; Photochemistry; Platelet Aggregation Inhibitors; Pyridines; Rolipram; Salicylic Acid; Stomach Diseases; Thromboxane B2 | 2012 |
Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arterial Pressure; Aspirin; Baroreflex; Chemoreceptor Cells; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Female; Heart Rate; Humans; Isometric Contraction; Male; Mechanoreceptors; Mechanotransduction, Cellular; Muscle, Skeletal; Reflex, Stretch; Thromboxane A2; Thromboxane B2; Time Factors | 2013 |
Association of cyclooxygenase-2 genetic variant with cardiovascular disease.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Heterozygote; Humans; Male; Multicenter Studies as Topic; Myocardial Infarction; Polymorphism, Genetic; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thromboxane B2 | 2014 |
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Aspirin; Cardiotonic Agents; Clopidogrel; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Lipoxins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Ticagrelor; Ticlopidine; Triazoles; Up-Regulation | 2014 |
Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Blood Chemical Analysis; Eugenol; Fibrinolytic Agents; Hemorheology; Male; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis; Thromboxane A2 | 2016 |
Reduced platelet aggregation in women after intercourse: a possible role for the cyclooxygenase pathway.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Alprostadil; Aspirin; Coitus; Condoms; Female; Humans; Indomethacin; Male; Middle Aged; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Semen | 2017 |
Low-dose Aspirin Inhibits Cardiac Sympathetic Activation and Vagal Withdrawal Response to Morning Rising.
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Baroreflex; Blood Pressure; Catecholamines; Circadian Rhythm; Female; Heart Rate; Humans; Male; Posture; Sympathetic Nervous System; Tilt-Table Test; Vagus Nerve; Young Adult | 2017 |
Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Clopidogrel; Cyclooxygenase 2; Gastric Mucosa; Male; Myocardial Infarction; Myocardium; Panax; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Saponins; Thromboxane B2; Ticlopidine; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A | 2018 |
[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclic AMP; Drugs, Chinese Herbal; Fruit; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Signal Transduction; Thrombosis; Thromboxane B2; Trichosanthes | 2019 |