aspirin has been researched along with 12-hydroxy-5,8,10,14-eicosatetraenoic acid in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (67.65) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, WC; Huang, JD; Lin, MT; Ning, CC | 1 |
| Figard, PH; Kaduce, TL; Leifur, R; Spector, AA | 1 |
| Chap, H; Douste-Blazy, L; Hullin, F; Pascal, M; Ragab-Thomas, JM; Sepulchre, C | 1 |
| Broekman, MJ; Eiroa, AM; Marcus, AJ | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Nizankowska, E; Radomski, M; Szczeklik, A; Wandzilak, M | 1 |
| Caruso, D; Galli, G; Maderna, P; Paoletti, R; Tremoli, E | 1 |
| Marcus, AJ | 1 |
| Brash, AR; Ingram, CD; Maas, RL | 1 |
| Buchanan, MR; Butt, RW; Hirsh, J; Markham, BA; Nazir, DJ | 1 |
| Broekman, MJ; Lorenzet, R; Marcus, AJ; Niemetz, J | 1 |
| Eynard, A; Galli, G; Gregori, M; Maderna, P; Tremoli, E | 1 |
| Beckman, BS; Fisher, JW; King, L; Mason-Garcia, M; Nystuen, L | 1 |
| Mahadevappa, VG; Vedelago, HR | 1 |
| Caruso, D; Galli, G; Maderna, P; Tremoli, E | 1 |
| Hajjar, DP; Hajjar, KA; Marcus, AJ | 1 |
| Barr, RD; Buchanan, MR; Gibson, BE; White, JG | 1 |
| Barbui, T; Buelli, M; Cortelazzo, S; De Gaetano, G; Viero, P | 1 |
| Bailey, JM; Bryant, RW; Fletcher-Cieutat, M; Vanderhoek, JY | 1 |
| Eynard, AR; Galli, G; Maderna, P; Magni, F; Paoletti, R; Tremoli, E | 1 |
| Altura, BM; Chand, N | 1 |
| Bianchine, J; Greenwald, JE; Metz, EN; Sagone, AL; Singh, D | 1 |
| Dahl, ML; Matintalo, M; Puustinen, T; Uotila, P | 1 |
| Collier, HO; McDonald-Gibson, RG; McDonald-Gibson, WJ; Power, GM | 1 |
| Cuatrecasas, P; McConnell, RT; Porter, NA; Siegel, MI | 1 |
| Fitzgerald, GA; Lawson, JA; Pratico, D | 1 |
| Beck, H; De Petrocellis, L; Di Marzo, V; Lehmann, WD; Leitz, T; Stephan, M | 1 |
| oude Egbrink, MG; Reneman, RS; Slaaf, DW; Tangelder, GJ | 1 |
| Dadaian, M; Granström, E; Westlund, P | 1 |
| Bredenberg, CE; Couper, L; Harvey, R; Himmelfarb, J | 1 |
| Calzada, C; Lagarde, M; Vericel, E | 1 |
| Barbui, T; Buchanan, MR; Cortelazzo, S; Falanga, A; Marchetti, M; Orlando, E | 1 |
| Ikeda, U; Maeda, Y; Murakami, Y; Ohya, K; Shimada, K; Shimpo, M | 1 |
| Ju, HK; Kwon, SW; Lee, CH; Lee, JG; Park, JH; Park, MK; Park, SJ | 1 |
| Goodall, AH; Hayes, PD; Jones, CI; McMahon, GS; Naylor, AR | 1 |
1 review(s) available for aspirin and 12-hydroxy-5,8,10,14-eicosatetraenoic acid
| Article | Year |
|---|---|
Transcellular metabolism of eicosanoids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Blood Platelets; Cell Communication; Cell Membrane Permeability; Eicosanoic Acids; Endothelium; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Neutrophils; Phospholipases; Prostaglandin-Endoperoxide Synthases; SRS-A | 1986 |
1 trial(s) available for aspirin and 12-hydroxy-5,8,10,14-eicosatetraenoic acid
| Article | Year |
|---|---|
Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Aged; Arachidonate 12-Lipoxygenase; Aspirin; Blood Platelets; Dalteparin; Endarterectomy, Carotid; Female; Gene Expression Regulation, Enzymologic; Heparin; Humans; Lipase; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Thromboxane B2 | 2013 |
32 other study(ies) available for aspirin and 12-hydroxy-5,8,10,14-eicosatetraenoic acid
| Article | Year |
|---|---|
Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Aspirin; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cycloheximide; Epidermal Growth Factor; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Microsomes; NADP; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Cell Compartmentation; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Epoprostenol; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandin-Endoperoxide Synthases; Serum Albumin; Thrombin | 1989 |
Stimulation of 12-HETE production in human platelets by an immunomodulator, LF 1695. Evidence for activation of arachidonate liberation coupled to cyclo-oxygenase inhibition.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Adjuvants, Immunologic; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Cyclooxygenase Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Albumin redirects platelet eicosanoid metabolism toward 12(S)-hydroxyeicosatetraenoic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Eicosanoids; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Serum Albumin | 1989 |
An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Arachidonate 12-Lipoxygenase; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Male; Middle Aged | 1988 |
Platelet 12-hydroxyeicosatetraenoic acid synthesis and aspirin: in vitro effects plasma and albumin.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Blood Platelets; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Plasma; Serum Albumin, Bovine | 1987 |
A secondary isotope effect in the lipoxygenase reaction.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Humans; Hydroxyeicosatetraenoic Acids; Isotope Labeling; Lipoxygenase; Mathematics | 1986 |
Role of lipoxygenase metabolism in platelet function: effect of aspirin and salicylate.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Thromboxane B2 | 1986 |
Enhancement of mononuclear procoagulant activity by platelet 12-hydroxyeicosatetraenoic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Blood Platelets; Cyclooxygenase Inhibitors; Endotoxins; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Thromboplastin | 1986 |
In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Platelet Aggregation; Pyrazoles; Sodium Salicylate; Thromboxane B2 | 1986 |
The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Erythropoiesis; Erythropoietin; Hydroxyeicosatetraenoic Acids; Liver; Masoprocol; Meclofenamic Acid; Mice; Phosphatidylinositols; Pyrazoles | 1987 |
Mobilization of arachidonic acid in collagen-stimulated human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Membrane Lipids; Phosphatidic Acids; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyrazoles | 1988 |
Differential effects of oral administrations to human volunteers of acetylsalicylic acid, sodium salicylate and indomethacin on 12-hydroxyeicosatetraenoic acid formation by stimulated platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Administration, Oral; Adult; Aspirin; Blood Platelets; Drug Administration Schedule; Female; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Male; Platelet Aggregation; Sodium Salicylate; Thromboxane B2 | 1988 |
Interactions of arterial cells. Studies on the mechanisms of endothelial cell modulation of cholesterol metabolism in co-cultured smooth muscle cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arteries; Aspirin; Cattle; Cell Communication; Cells, Cultured; Cholesterol Esters; Dinoprostone; Endothelium; Epoprostenol; Hydrolysis; Hydroxyeicosatetraenoic Acids; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandins E; Sterol Esterase | 1987 |
Primary thrombocythaemia in childhood: symptomatic episodes and their relationship to thromboxane A2, 6-keto-PGE1 and 12-hydroxy-eicosatetraenoic acid production: a case report.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Alprostadil; Arachidonate 12-Lipoxygenase; Aspirin; Asthma; Blood Platelets; Child; Eosinophilia; Humans; Hydroxyeicosatetraenoic Acids; Male; Platelet Aggregation; Thrombocytosis; Thromboxane A2 | 1987 |
Aspirin and risk of bleeding in patients with thrombocythemia.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood Platelets; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Myeloproliferative Disorders; Polycythemia Vera; Risk; Serotonin; Thrombocythemia, Essential; Thromboxane B2; Time Factors; von Willebrand Factor | 1987 |
Aspirin enhances the sensitivity of human platelet 12-lipoxygenase to inhibition by 15-HETE, an endogenous regulator.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Drug Synergism; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase Inhibitors | 1985 |
Aspirin inhibits platelet 12-hydroxy-eicosatetraenoic acid formation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Aspirin; Blood Platelets; Collagen; Depression, Chemical; Humans; Hydroxyeicosatetraenoic Acids; Male; Platelet Aggregation; Thromboxane B2 | 1986 |
Lipoxygenase pathway and hydroperoxy acids: possible relevance to aspirin-induced asthma and hyperirritability of airways in asthmatics.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acids; Aspirin; Asthma; Autacoids; Humans; Leukotrienes; Lipid Peroxides; Lipoxygenase; Peroxides; Prostaglandin-Endoperoxide Synthases | 1981 |
Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Carbon Dioxide; Cell Separation; Dimethyl Sulfoxide; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Thromboxane B2; Time Factors | 1981 |
The effects of aspirin and dipyridamole on the metabolism of arachidonic acid in human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dipyridamole; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Leukotrienes; Male; Thromboxane B2 | 1983 |
The effect of acetylsalicylate on aggregation and arachidonate metabolism by human platelets suspended in plasma or buffer.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Buffers; Humans; Phospholipids; Platelet Aggregation | 1984 |
Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Peroxidases; Salicylates | 1980 |
Cyclooxygenase-dependent formation of the isoprostane 8-epi prostaglandin F2 alpha.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Blood Platelets; Dinoprost; Humans; Hydroxyeicosatetraenoic Acids; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 1994 |
Possible involvement of arachidonic acid and eicosanoids in metamorphic events in Hydractinia echinata (Coelenterata; Hydrozoa).
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aspirin; Carbon Radioisotopes; Eicosanoids; Gas Chromatography-Mass Spectrometry; Hydra; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Masoprocol; Metamorphosis, Biological; Phospholipids | 1994 |
Different roles of prostaglandins in thromboembolic processes in arterioles and venules in vivo.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arterioles; Aspirin; Epoprostenol; Female; Hydroxyeicosatetraenoic Acids; Leukocytes; Male; Mesentery; Platelet Activation; Prostaglandins; Rabbits; Receptors, Thromboxane; Regional Blood Flow; Sulfonamides; Thromboembolism; Thromboxane A2; Venules; Videotape Recording | 1993 |
Albumin prevents metabolism of 12-hydroxyeicosatetraenoic acid by leukocytes in vitro.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Aspirin; Blood Platelets; Calcimycin; Calcium; Carrier Proteins; Chromatography, High Pressure Liquid; Coculture Techniques; Depression, Chemical; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Humans; Ionophores; Leukocytes; Myelin P2 Protein; Neoplasm Proteins; Platelet Activation; Serum Albumin; Tumor Suppressor Proteins | 1996 |
Aspirin enhances platelet-derived growth factor-induced vascular smooth muscle cell proliferation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aorta; Arachidonate 12-Lipoxygenase; Arachidonic Acids; Aspirin; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Graft Occlusion, Vascular; Humans; Hyperplasia; Multivariate Analysis; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Platelet-Derived Growth Factor; Regression Analysis; Thymidine; Tritium; Tunica Intima; Vascular Surgical Procedures | 1997 |
Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Deferoxamine; Enzyme Activation; Fatty Acids, Unsaturated; Humans; Hydrazines; Hydrogen Peroxide; Leukotrienes; Lipid Peroxides; Oligopeptides; Peroxides; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1997 |
Aspirin increases the bleeding side effects in essential thrombocythemia independent of the cyclooxygenase pathway: role of the lipoxygenase pathway.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Bleeding Time; Blood Coagulation; Humans; Lipoxygenase; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Thrombocythemia, Essential; Thromboxane A2 | 1998 |
Effects of aspirin-like drugs on nitric oxide synthesis in rat vascular smooth muscle cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; Indomethacin; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Sodium Salicylate | 2000 |
Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rk₁ reveals attenuated 12-HETE production.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ginsenosides; Male; Membrane Proteins; Metabolome; Metabolomics; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Principal Component Analysis; Protein Transport; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 2012 |