asperparaline-a has been researched along with paraherquamide* in 3 studies
2 review(s) available for asperparaline-a and paraherquamide
| Article | Year |
|---|---|
Paraherquamides, brevianamides, and asperparalines: laboratory synthesis and biosynthesis. An interim report.
Studies from our laboratories on the paraherquamide, brevianamide, and asperparaline families of natural products are reviewed. It has been proposed that the unique core ring system that is common to this family of compounds arises by a biological intramolecular Diels-Alder cycloaddition reaction. Key biosynthetic studies are described, along with classical synthetic approaches as well as those inspired by Nature for the synthesis of these interesting molecules. Topics: Alkaloids; Cyclization; Fungi; Indolizines; Piperazines; Spiro Compounds | 2003 |
Total synthesis and biosynthesis of the paraherquamides: an intriguing story of the biological Diels-Alder construction.
The syntheses and biosyntheses of the paraherquamide and brevianamide families of prenylated indole-derived alkaloids are reviewed. It has been proposed that the unique bicyclo[2.2.2]diazaoctan ring system that is common to this family of natural products, arises by a biological intramolecular Diels-Alder cycloaddition reaction. Both synthetic approaches and total syntheses of several members of this family of natural products are reviewed. The biosynthesis of these alkaloids has also constituted an active area of research and the current state of knowledge on the biosynthesis of these natural products are reviewed. Topics: Alkaloids; Bridged Bicyclo Compounds; Indoles; Indolizines; Piperazines; Spiro Compounds | 2002 |
1 other study(ies) available for asperparaline-a and paraherquamide
| Article | Year |
|---|---|
Novel anthelmintic metabolites from an Aspergillus species; the aspergillimides.
Two members of a novel class of anthelmintics, the aspergillimides, have been isolated from the Aspergillus strain IMI 337664. This novel fungus also produced two known and one structurally novel paraherquamide. This paper describes the fermentation, isolation, structure elucidation and anthelmintic activity of aspergillimide (VM55598, 1), 16-keto aspergillimide (SB202327, 2), and the paraherquamides VM54159 (3), SB203105 (4) and SB200437 (5). The aspergillimides are equivalent to paraherquamides which have lost both the dioxygenated 7-membered ring and the phenyl ring to which this is fused; gaining in their place a C8-keto group. SB203105 is the first example of a 4-substituted paraherquamide. Topics: Alkaloids; Animals; Anthelmintics; Aspergillus; Fermentation; Gerbillinae; Indole Alkaloids; Indoles; Indolizines; Molecular Structure; Piperazines; Spiro Compounds; Trichostrongylosis | 1997 |