aspartic acid has been researched along with thymidine in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (83.33) | 18.7374 |
| 1990's | 5 (9.26) | 18.2507 |
| 2000's | 4 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakayama, H; Weser, E | 1 |
| Davison, P; Karasek, M; Liu, S | 1 |
| Kwong, LK; Tsuboi, KK | 1 |
| Goldberg, RM; Krook, JE; Kugler, JW; Laurie, JA; Moertel, CG; O'Connell, MJ; Pfeifle, DM; Rubin, J; Wieand, HS; Windschitl, HE | 1 |
| Borissenko, M; Calderón, M; Clarke, S; George-Nascimento, C; Kuo, J; Lowenson, J; Medina-Selby, A; Randolph, A | 1 |
| Buroker, TR; Cullinan, SA; Everson, LK; Fleming, TR; Klaassen, DJ; Krook, JE; Laurie, JA; Mailliard, JA; Marschke, RF; Moertel, CG | 1 |
| Hoth, DF; King, SA; Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Bhalla, K; Grant, S | 1 |
| Akazawa, S; Ayusawa, D; Kumai, R; Seno, T; Shimizu, K; Yoshida, S | 1 |
| Bedikian, A; Bodey, GP; Chiuten, DF; Freireich, EJ; Valdivieso, M | 1 |
| Bedikian, A; Benvenuto, JA; Bodey, GP; Chiuten, DF; Freireich, EJ; Loo, TL; Miller, A; Valdivieso, M | 1 |
| Reusser, F | 1 |
| Byars, N; Kidson, C | 1 |
| Koukalová, B; Kuhrová, V; Soska, J | 1 |
| Plagemann, PG | 1 |
| Chaiken, IM; Sánchez, GR | 1 |
| Hoogenraad, J; Stark, GR; Yoshida, T | 1 |
| Gudas, LJ; Pardee, AB | 1 |
| Engelking, HM; Seidler, RJ | 1 |
| Urban, JE | 1 |
| Wysor, MS; Zollinhofer, RE | 1 |
| Howell, BA; Kizer, DE | 2 |
| Brock, ML; Brock, TD | 1 |
| Etheredge, EE; Najarian, JS; Shons, AR | 1 |
| Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N | 1 |
| Bresnick, E; Burleson, SS | 1 |
| Frost, P; Giegel, JL; Stolfi, LM; Weinstein, GD | 1 |
| Greco, AE; Schneider, WC | 1 |
| Downing, M; Hutson, JY | 1 |
| Gale, GR; Schmidt, GB | 1 |
| Groth, DP; Jiang, N | 1 |
| Ginger, CD; Gutteridge, WE; Heyworth, PG | 1 |
| Shapiro, WR; Young, DF | 1 |
| Campagnari, F; Carroll, MJ; Clerici, L; Merlini, M; Vercellini, L | 1 |
| Hahn, RG; Kvols, LK; Moertel, CG; O'Connell, MJ; Rubin, J; Schutt, AJ | 1 |
| Casper, ES; Kemeny, N; Martin, DS; Michaelson, RA; Young, CW | 1 |
| Panova, LA; Smirnov, SG; Voskun, SE | 1 |
| Ardawi, MS; Newsholme, EA | 1 |
| Henderson, JF; Hunting, D | 1 |
| Khalil, FL; Lea, MA | 1 |
| Grindey, GB; Kinahan, JJ; Kowal, EP | 1 |
| Bussolati, O; Franchi-Gazzola, R; Gazzola, GC; Rotoli, BM; Uggeri, J | 1 |
| Black, ME; Drake, RR; Rechtin, TM | 1 |
| Biemann, HP; Harmer, SL; Koshland, DE | 1 |
| Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S | 1 |
| CREASEY, WA; MARKIW, ME | 1 |
| BENNETT, LL; SMITHERS, D; WARD, CT | 1 |
| AMSTEY, M; BROWN, O; MCCARTY, KS; WOODSON, B | 1 |
| CURCI, MR; DONACHI, WD | 1 |
| Chang, ZF; Ke, PY; Li, CL; Lu, CY | 1 |
| Chang, YR; Chen, JY; Chen, MC; Hsu, TY; Wu, CC | 1 |
| Meyer, RD; Mohammadi, M; Rahimi, N | 1 |
3 review(s) available for aspartic acid and thymidine
| Article | Year |
|---|---|
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine | 1987 |
Biochemical modulation: application of laboratory models to the clinic.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1986 |
Neurological complications of antineoplastic therapy.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Aspartic Acid; Cisplatin; Cytarabine; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Phosphonoacetic Acid; Thymidine; Vinblastine; Vincristine | 1984 |
2 trial(s) available for aspartic acid and thymidine
| Article | Year |
|---|---|
A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer.
Topics: Adult; Aged; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine | 1990 |
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Levamisole; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Random Allocation; Rectal Neoplasms; Semustine; Streptozocin; Thymidine; Vincristine | 1985 |
49 other study(ies) available for aspartic acid and thymidine
| Article | Year |
|---|---|
Pyrimidine biosynthetic enzymes in rat intestine after small bowel resection.
Topics: Adaptation, Physiological; Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Radioisotopes; DNA; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Orotic Acid; Phosphotransferases; Pyrimidines; Rats; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1975 |
Limitations in the use of [3H]thymidine incorporation into DNA as an indicator of epidermal keratinocyte proliferation in vitro.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Cell Division; DNA; Humans; Isotope Labeling; Phosphates; Phosphorus Radioisotopes; Rabbits; Skin; Skin Physiological Phenomena; Thymidine; Tritium | 1979 |
Antiproliferative agents and differential survival between normal and cancer cells.
Topics: Adenocarcinoma; Aspartic Acid; Cell Cycle; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1978 |
Replacement of a labile aspartyl residue increases the stability of human epidermal growth factor.
Topics: Amino Acid Sequence; Aspartic Acid; Cells, Cultured; Chymotrypsin; DNA Replication; Drug Stability; Epidermal Growth Factor; Humans; Methylation; Molecular Sequence Data; Oligopeptides; Peptide Mapping; Recombinant Proteins; Thermolysin; Thymidine | 1990 |
Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.
Topics: 3-Deazauridine; Amides; Aspartic Acid; Cell Division; Cell Line; Deoxycytidine; Deoxycytidine Kinase; Drug Interactions; Humans; Leukemia, Experimental; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine | 1987 |
[Biochemical modulation of 5-FU by thymidine and N-phosphoacetyl-L-aspartate: the relation between 5-FU incorporation into RNA and its cytocidal effect].
Topics: Animals; Aspartic Acid; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Thymidine; Tumor Stem Cell Assay | 1986 |
Phase I-II clinical trial of thymidine, 5-FU, and PALA given in combination.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine | 1985 |
Sequential administration of thymidine, 5-fluorouracil, and PALA. A phase I-II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Carcinoma, Bronchogenic; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Half-Life; Humans; Infusions, Parenteral; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine | 1985 |
Mode of action of zorbamycin.
Topics: Anti-Bacterial Agents; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Bleomycin; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Copper; DNA Nucleotidyltransferases; DNA, Bacterial; Escherichia coli; Genetic Code; Genetics, Microbial; Nucleic Acid Denaturation; Peptides; Protoplasts; Ribosomes; RNA, Bacterial; Spectrophotometry; Sucrose; Thymidine; Tritium; Uracil | 1971 |
Programmed synthesis and export of immunoglobulin by synchronized myeloma cells.
Topics: Animals; Aspartic Acid; Cell Count; Cell Line; Collagen; DNA, Neoplasm; Fibroblasts; gamma-Globulins; Glutamates; Glycine; Immunoglobulins; In Vitro Techniques; Mice; Plasmacytoma; Proline; Thymidine; Tritium; Valine | 1970 |
Effect of rifampicin and free amino acids on replication of DNA in Lactobacillus acidophilus.
Topics: Amino Acids; Aspartic Acid; Chloramphenicol; Dactinomycin; Deoxyadenosines; DNA Replication; DNA, Bacterial; Glutamates; Lactobacillus acidophilus; Rifampin; RNA, Bacterial; Thymidine; Time Factors; Uracil | 1974 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Diffusion; DNA; Electrophoresis; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium; Uracil; Uridine | 1971 |
Active site properties of (aspartic acid 43)-semisynthetic nuclease-T'.
Topics: Aspartic Acid; Binding Sites; Calcium; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Affinity; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dialysis; Glutamates; Nitriles; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Polysaccharides; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Staphylococcus; Thymidine; Thymine Nucleotides; Trypsin | 1972 |
Inhibition by N-(phosphonacetyl)-L-aspartate of aspartate transcarbamylase activity and drug-induced cell proliferation in mice.
Topics: Administration, Oral; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Radioisotopes; Cell Division; DNA; Female; Injections, Subcutaneous; Isoproterenol; Jejunum; Mice; Organophosphonates; Phosphonoacetic Acid; Spleen; Submandibular Gland; Thymidine; Time Factors; Tritium | 1974 |
Deoxyribonucleic acid synthesis during the division cycle of Escherichia coli: a comparison of strains B-r, K-12, 15, and 15T- under conditions of slow growth.
Topics: Acetates; Aspartic Acid; Cell Count; Cell Division; Cell Wall; Centrifugation, Density Gradient; Culture Media; DNA Replication; DNA, Bacterial; Escherichia coli; Proline; Succinates; Sucrose; Thymidine; Thymine; Time Factors; Tritium | 1974 |
The involvement of extracellular enzymes in the metabolism of Bdellovibrio.
Topics: Aeromonas; Amino Acids; Aspartic Acid; Bacteria; Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Glycine; Hydrolysis; Peptide Hydrolases; Ribonucleases; RNA, Bacterial; Thymidine; Tritium; Uracil | 1974 |
Isolation of a new division altered mutant of Escherichia coli 15T.
Topics: Aspartic Acid; Cell Division; Centrifugation, Density Gradient; Chromosomes; Escherichia coli; Glucose; Isotope Labeling; Mutation; Succinates; Thymidine; Time Factors; Tritium | 1974 |
On the mode of action of silver sulfadiazine.
Topics: Aspartic Acid; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxyribonucleases; DNA Nucleotidyltransferases; DNA Replication; DNA, Bacterial; Nucleic Acid Denaturation; Protein Binding; Pseudomonas aeruginosa; Ribosomes; RNA, Bacterial; Silver; Spectrophotometry; Stereoisomerism; Sulfadiazine; Thymidine; Tritium; Uracil | 1972 |
Synchrony between DNA synthesis and thymidine incorporation into DNA in regenerating rat liver.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, DEAE-Cellulose; DNA; Female; Formates; Hydrocortisone; Hydrolysis; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Proteins; Rats; Stress, Physiological; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
Temperature optimum of non-sulphur bacteria from a spring at 90C.
Topics: Aspartic Acid; Bacteria; Carbon Isotopes; Culture Media; Hot Temperature; Hydrogen-Ion Concentration; Lactates; Leucine; Phenylalanine; Temperature; Thymidine; Tritium; Water Microbiology | 1971 |
On relationships between synthesis of DNA and incorporation of deoxythymidine into DNA during myocardial infarctions induced in rats by isoproterenol.
Topics: Adenine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cytosine; DNA; Female; Formates; Glycine; Isoproterenol; Leucine; Metabolism; Muscle Proteins; Myocardial Infarction; Myocardium; Rats; Stimulation, Chemical; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1972 |
The effect of L-asparaginase in mixed leukocyte culture.
Topics: Asparaginase; Asparagine; Aspartic Acid; Culture Techniques; Depression, Chemical; Glutamine; Humans; Leukocytes; Thymidine; Tritium | 1971 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Rates of turnover of deoxythymidine kinase and of its template RNA in Novikoff hepatoma and neonatal liver.
Topics: Animals; Animals, Newborn; Ascitic Fluid; Aspartic Acid; Carbon Isotopes; Cycloheximide; Dactinomycin; Deoxyribonucleosides; Hematoma; Liver; Male; Neoplasms, Experimental; Phosphotransferases; Protein Biosynthesis; Puromycin; Rats; RNA; Templates, Genetic; Thymidine; Time Factors; Uridine | 1970 |
Androgenic regulation of nucleic acid and protein synthesis in the hamster flank organ and other tissues.
Topics: Amino Acids; Androgens; Animals; Aspartic Acid; Carbon Isotopes; Castration; Cricetinae; DNA; Male; Methionine; Prostate; Protein Biosynthesis; Proteins; RNA; Sebaceous Glands; Seminal Vesicles; Stimulation, Chemical; Testosterone; Thymidine; Tritium; Uridine | 1971 |
Incorporation of pyrimidine deoxyribonucleosides into liver lipids and other components.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deoxyribonucleosides; Deoxyuridine; DNA; Fatty Acids; Glutamates; Glycerides; Glycerol; Glycerylphosphorylcholine; Hydrolysis; Lipids; Liver; Male; Methionine; Mice; Microsomes, Liver; Mitochondria, Liver; Nucleosides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Biosynthesis; Rats; Serine; Thymidine; Thymine; Tritium | 1971 |
Pyrimidine biosynthesis in Lactobacillus leichmannii.
Topics: Arginine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Guanine Nucleotides; Hydrolases; Lactobacillus; Nucleotides; Ornithine Carbamoyltransferase; Phosphotransferases; Pyrimidines; Thymidine; Transferases; Uracil | 1968 |
Mode of action of alanosine.
Topics: Adenine; Animals; Antifungal Agents; Antiviral Agents; Aspartic Acid; Azaserine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Depression, Chemical; Formates; Glutamine; Glycine; Guanine; Leucine; Nitrosamines; Nucleotides; Propionates; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1968 |
The role of deoxyribose 5-phosphate aldolase in the synthesis of deoxyribonucleotide in mammalian cells.
Topics: Adenine; Aldehyde-Lyases; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA; Glycine; In Vitro Techniques; Liver; Liver Regeneration; Mice; Nucleotides; Orotic Acid; Protein Biosynthesis; Rats; RNA; Subcellular Fractions; Threonine; Thymidine; Uridine | 1966 |
Pyrimidine metabolism in Trichomonas vaginalis.
Topics: Animals; Aspartic Acid; Bicarbonates; Cytosine Nucleotides; Orotic Acid; Pyrimidines; Thymidine; Thymidylate Synthase; Trichomonas vaginalis; Uracil Nucleotides | 1984 |
The toxicity of tritium: the effects of tritiated amino-acids on preimplanted mouse embryos.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Blastocyst; Female; Histidine; Lysine; Mice; Thymidine; Time Factors; Tritium | 1984 |
Clinical trial of sequential N-phosphonacetyl-L-aspartate, thymidine, and 5-fluorouracil in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Ataxia; Colonic Neoplasms; Confusion; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine | 1984 |
Phase I evaluation of a biochemically designed combination: PALA, thymidine, and 5-FU.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Fluorouracil; Humans; Neoplasms; Nervous System; Phosphonoacetic Acid; Thymidine | 1984 |
[Growth dyssymmetry of Shigella flexneri 6(762 S) cells].
Topics: Aspartic Acid; Autoradiography; Bacteriological Techniques; Cell Division; Microscopy, Electron; Shigella flexneri; Threonine; Thymidine | 1982 |
Glutamine metabolism in lymphocytes of the rat.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Cells, Cultured; Concanavalin A; Glucose; Glutamine; Kinetics; Lymphocyte Activation; Lymphocytes; Male; Oxygen Consumption; Picolinic Acids; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Relationship between ribo- and deoxyribonucleotide concentrations and biological parameters in cultured Chinese hamster ovary cells.
Topics: Amides; Animals; Aspartic Acid; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Deoxyribonucleotides; Female; Mycophenolic Acid; Ovary; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribonucleotides; Ribose; Thymidine | 1982 |
X-irradiation and the incorporation of precursors for salvage and de novo synthesis of DNA in hepatomas and liver.
Topics: Animals; Aspartic Acid; DNA; DNA Repair; DNA, Neoplasm; Liver; Liver Neoplasms, Experimental; Male; Rats; Thymidine; Uracil; X-Rays | 1981 |
Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cells, Cultured; Cytarabine; Cytidine; Drug Therapy, Combination; Leukemia L1210; Mice; Phosphonoacetic Acid; Thymidine | 1981 |
The relationship between sodium-dependent transport of anionic amino acids and cell proliferation.
Topics: 3T3 Cells; Animals; Aspartic Acid; Binding Sites; Biological Transport; Bromodeoxyuridine; Cell Division; Culture Media, Serum-Free; Cycloheximide; Kinetics; Mice; Sodium; Thymidine | 1993 |
Effect on substrate binding of an alteration at the conserved aspartic acid-162 in herpes simplex virus type 1 thymidine kinase.
Topics: Adenosine Triphosphate; Aspartic Acid; Base Sequence; Binding Sites; Conserved Sequence; DNA, Viral; Herpesvirus 1, Human; Humans; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Serine-Threonine Kinases; Substrate Specificity; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Viral Proteins | 1996 |
An aspartate/insulin receptor chimera mitogenically activates fibroblasts.
Topics: 3T3 Cells; Animals; Aspartic Acid; Cell Division; Cell Membrane; Culture Media, Serum-Free; DNA; Escherichia coli; Fluorescent Antibody Technique; Mammals; Mice; Molecular Weight; Phosphorylation; Receptor, Insulin; Receptors, Amino Acid; Recombinant Fusion Proteins; Thymidine | 1996 |
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine | 2001 |
BIOCHEMICAL EFFECTS OF THE VINCA ALKALOIDS--I. EFFECTS OF VINBLASTINE ON NUCLEIC ACID SYNTHESIS IN MOUSE TUMOR CELLS.
Topics: Animals; Aspartic Acid; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Metabolism; Mice; Nucleosides; Pharmacology; Research; Ribosomes; RNA; RNA, Neoplasm; Thymidine; Tritium; Vinblastine; Vinca Alkaloids | 1964 |
INHIBITION OF DNA SYNTHESIS IN MAMMALIAN CELLS BY ACTIDIONE.
Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Carcinoma, Squamous Cell; Cycloheximide; Cytosine Nucleotides; DNA; DNA Replication; DNA, Neoplasm; Formates; Glycine; Guanine Nucleotides; Leucine; Metabolism; Neoplasms; Nucleosides; Nucleotides; Nucleotidyltransferases; Orotic Acid; Pharmacology; Research; RNA; RNA, Neoplasm; Thymidine; Tissue Culture Techniques; Tritium | 1964 |
ARGININE AS A PRECURSOR OF PYRIMIDINES IN STRAIN L-929 FIBROBLASTS INFECTED WITH PLEUROPNEUMONIA-LIKE ORGANISMS.
Topics: Arginase; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Connective Tissue; Fibroblasts; Glutamine; Ligases; Metabolism; Mycoplasma; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Phosphates; Phosphotransferases; Proline; Proteins; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Uracil; Urea; Ureohydrolases | 1964 |
AN ATTEMPT TO FIND PYRIMIDINE INHIBITORS OF A MAMMALIAN ASPARTATE CARBAMOYLTRANSFERASE.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Isotopes; Colorimetry; Cytosine Nucleotides; Enzyme Inhibitors; Erythrocytes; Nucleosides; Nucleotides; Pyrimidines; Rabbits; Research; Thymidine; Thymine; Tissue Extracts; Transferases; Uracil Nucleotides | 1964 |
Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site.
Topics: Adenosine Triphosphate; Aspartic Acid; Catalysis; Cell Cycle; Cell Line; Chromatography; Chromatography, Gel; Cytosol; Dimerization; Dose-Response Relationship, Drug; G2 Phase; Humans; Kinetics; Mitosis; Models, Biological; Mutation; Phosphorylation; Plasmids; Protein Structure, Quaternary; Serine; Thymidine; Thymidine Kinase | 2004 |
Identification and characterization of the conserved nucleoside-binding sites in the Epstein-Barr virus thymidine kinase.
Topics: Amino Acid Sequence; Aspartic Acid; Binding, Competitive; Blotting, Western; Conserved Sequence; Herpesvirus 4, Human; Histidine; Humans; Inhibitory Concentration 50; Kinetics; Metals; Models, Molecular; Molecular Sequence Data; Mutation; Nucleosides; Phenylalanine; Protein Conformation; Substrate Specificity; Thymidine; Thymidine Kinase; Valine | 2004 |
A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blotting, Western; Cell Membrane; Cell Proliferation; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Immunoprecipitation; Ligands; Mice; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; NIH 3T3 Cells; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Thymidine; Time Factors; Tyrosine; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2006 |