aspartic acid has been researched along with riluzole in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Blanchard, JC; Doble, A; Hubert, JP | 1 |
| Barbeito, L; Chéramy, A; Glowinski, J; Godeheu, G | 1 |
| Blin, O; Dusticier, N; Nieoullon, A; Samuel, D | 1 |
| Becquet, D; Faudon, M; Hery, F | 1 |
| Doble, A; Hubert, JP | 1 |
| D'Angio, M; Scatton, B; Serrano, A | 1 |
| Martin, D; Nadler, JV; Thompson, MA | 1 |
| Arnold, DL; Cashman, NR; Genge, A; Kalra, S | 1 |
| Arnold, DL; Cashman, NR; Kalra, S | 1 |
| Abarca, C; Contreras, E; Oliva, P; Sepúlveda, MJ; Silva, E | 1 |
| Janik, P; Kwieciński, H; Niebroj-Dobosz, I | 1 |
| Hewett, SJ; Vidwans, AS | 1 |
| Babot, Z; Cristòfol, R; Suñol, C | 1 |
| Camacho, A; Massieu, L; Montiel, T | 1 |
| Amin, M; Rawls, SM; Robinson, W; Tallarida, R | 1 |
| Charney, DS; Coplan, JD; Mao, X; Mathew, SJ; Price, RB; Shungu, DC; Smith, EL | 1 |
| Cryan, JF; Dinan, TG; Gosselin, RD; Julio-Pieper, M; O'Connor, RM; Tramullas, M | 1 |
| Arun, P; Moffett, JR; Namboodiri, AM | 1 |
| Cifra, A; Nani, F; Nistri, A | 1 |
| Abdallah, CG; Coplan, JD; Jackowski, A; Mao, X; Mathew, SJ; Sato, JR; Shungu, DC | 2 |
| Abaei, A; Boeckers, TM; Fegert, JM; Hengerer, B; Nespoli, E; Rasche, V; Rizzo, F | 1 |
| Barkhof, F; Chataway, J; DeAngelis, F; Doshi, A; Gandini Wheeler-Kingshott, CAM; John, NA; MacManus, D; Marshall, I; Monteverdi, A; Parker, RA; Plantone, D; Prados, F; Schneider, T; Solanky, BS; Stutters, J; Weir, CJ | 1 |
1 review(s) available for aspartic acid and riluzole
| Article | Year |
|---|---|
Biological markers in the diagnosis and treatment of ALS.
Topics: Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Creatine; Disease Progression; Electromyography; Humans; Magnetic Resonance Imaging; Monitoring, Physiologic; Neuroprotective Agents; Riluzole; Tomography, Emission-Computed | 1999 |
5 trial(s) available for aspartic acid and riluzole
| Article | Year |
|---|---|
Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Excitatory Amino Acid Antagonists; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Motor Cortex; Motor Neurons; Riluzole | 1998 |
Effect of Riluzole on serum amino acids in patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Aspartic Acid; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Reference Values; Riluzole; Time | 2002 |
Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Aspartic Acid; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Personality Inventory; Prefrontal Cortex; Riluzole; Treatment Outcome | 2008 |
Riluzole effect on occipital cortex: a structural and spectroscopy pilot study.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Aspartic Acid; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Pilot Projects; Riluzole; Treatment Outcome | 2012 |
NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study.
Topics: Adult; Amiloride; Aspartic Acid; Biomarkers; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Disability Evaluation; Disease Progression; Double-Blind Method; Female; Fluoxetine; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Neuroimaging; Neuroprotective Agents; Proton Magnetic Resonance Spectroscopy; Protons; Riluzole | 2020 |
18 other study(ies) available for aspartic acid and riluzole
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on D-[3H]aspartate release from cultured cerebellar granule cells.
Topics: Anesthetics; Aspartic Acid; Carbachol; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Pertussis Toxin; Riluzole; Thiazoles; Virulence Factors, Bordetella | 1992 |
Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo.
Topics: Amino Acids; Anesthetics; Animals; Aspartic Acid; Calcium; Cats; Caudate Nucleus; Female; Glutamates; Glutamic Acid; Male; Potassium; Riluzole; Thiazoles | 1992 |
Effects of riluzole (2-amino-6-trifluoromethoxy benzothiazole) on striatal neurochemical markers in the rat, with special reference to the dopamine, choline, GABA and glutamate synaptosomal high affinity uptake systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Biomarkers; Choline; Corpus Striatum; Culture Media; Dopamine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydroxyindoleacetic Acid; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar; Riluzole; Serotonin; Synaptic Transmission; Synaptosomes; Thiazoles; Tritium | 1992 |
In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Riluzole; Serotonin; Spinal Cord; Synaptic Transmission; Tetrodotoxin; Thiazoles | 1990 |
Ibotenic acid stimulates D-[3H]aspartate release from cultured cerebellar granule cells.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Ibotenic Acid; Oxazoles; Phosphoserine; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Riluzole; Thiazoles | 1989 |
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles | 1989 |
The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1.
Topics: Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Potassium; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Riluzole; Thiazoles | 1993 |
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia.
Topics: Analysis of Variance; Animals; Arginine; Aspartic Acid; Carrageenan; Citrulline; Dialysis Solutions; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Male; Microdialysis; Morphine; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Thalamic Nuclei | 2000 |
Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.
Topics: Animals; Aspartic Acid; Cell Death; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Extracellular Space; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Mice; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzoates; Riluzole; Synapses; Tetanus Toxin | 2004 |
Excitotoxic death induced by released glutamate in depolarized primary cultures of mouse cerebellar granule cells is dependent on GABAA receptors and niflumic acid-sensitive chloride channels.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Mice; Naphthalenes; Neurons; Neurotoxins; Niflumic Acid; Oxepins; Potassium Chloride; Propidium; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Riluzole; Tritium | 2005 |
The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cell Death; Energy Metabolism; Excitatory Amino Acids; Exocytosis; Extracellular Fluid; Glycolysis; Hippocampus; Male; Microdialysis; Nerve Degeneration; Nitrobenzoates; Phloretin; Rats; Rats, Wistar; Riluzole; Stilbenes; Tamoxifen; Vesicular Glutamate Transport Proteins; Voltage-Dependent Anion Channels | 2006 |
The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Bacterial Agents; Aspartic Acid; beta-Lactams; Body Temperature; Ceftriaxone; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors | 2007 |
Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms.
Topics: Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glutamic Acid; Irritable Bowel Syndrome; Male; Maternal Deprivation; Motor Activity; Rats; Rats, Sprague-Dawley; Riluzole; Spinal Cord; Stress, Psychological | 2010 |
Riluzole decreases synthesis of N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells.
Topics: Aspartic Acid; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Riluzole; Time Factors | 2010 |
Riluzole is a potent drug to protect neonatal rat hypoglossal motoneurons in vitro from excitotoxicity due to glutamate uptake block.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Astrocytes; Bicuculline; Biomarkers; Convulsants; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Hypoglossal Nerve; Motor Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Riluzole; Strychnine | 2011 |
A pilot study of hippocampal volume and N-acetylaspartate (NAA) as response biomarkers in riluzole-treated patients with GAD.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Biomarkers; Female; Hippocampus; Humans; Male; Organ Size; Pilot Projects; Riluzole | 2013 |
Aripiprazole and Riluzole treatment alters behavior and neurometabolites in young ADHD rats: a longitudinal
Topics: Animals; Antipsychotic Agents; Aripiprazole; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Brain; Disease Models, Animal; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Motor Activity; Neuroprotective Agents; Rats; Rats, Inbred WKY; Riluzole | 2017 |