Page last updated: 2024-08-17

aspartic acid and quinolinic acid

aspartic acid has been researched along with quinolinic acid in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (67.80)	18.7374
1990's	8 (13.56)	18.2507
2000's	5 (8.47)	29.6817
2010's	6 (10.17)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ	1
Du, F; Schwarcz, R	1
Rios, C; Santamaria, A	1
Choi, DW; Hartley, DM; Koh, J; Weiss, JH	1
Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ	1
Meguri, H; Ogita, K; Ohgaki, T; Uchida, S; Yoneda, Y	1
Choi, DW; Koh, JY	1
Klockgether, T; Lehmann, J; Schwarz, M; Sontag, KH; Turski, L	1
Collins, JF; Meldrum, BS; Turski, L	1
Cotman, CW; Ganong, AH	1
Aleksandrov, VG; Lapin, IP; Mandel'shtam, IuE; Ryzhov, IV; Slepokurov, MV	1
Curry, K; Magnuson, DS; McLennan, H; Peet, MJ	2
Addae, JI; Stone, TW	2
Wieloch, T	1
Choi, DW; Koh, JY; Peters, S	1
Stone, TW	1
Connick, JH; Stone, TW	2
Lodge, D; Martin, D	1
Choi, DW; Koh, J; Peters, S	1
Connick, JH; English, M; Hastings, MH; Stone, TW; Winn, P	1
Davies, SW; Roberts, PJ	1
Lees, GJ	1
Samanin, R; Vezzani, A; Wu, HQ	1
Burton, NR; Smith, DA; Stone, TW	2
Burton, NR; Smith, DA; Stone, TW; Williams, TL	1
Foster, AC; Gill, R; Woodruff, GN	1
Hankins, MW; Ruddock, KH	1
Farley, JM; Huang, HM; Jin, C; Rockhold, RW	1
Garthwaite, G; Garthwaite, J	1
Carroll, BL; Crowley, WR; Johnson, MD; Whetsell, WO	1
Herrling, PL; Klockgether, T; Sontag, KH; Turski, L; Watkins, JC	1
Choi, DW; Peters, S; Viseskul, V	1
French, ED; Schwarcz, R; Ungerstedt, U; Vezzani, A	1
McLennan, H	1
Perkins, MN; Stone, TW	4
Herrling, PL; Morris, R; Salt, TE	1
MacDonald, MJ	1
Fedele, E; Foster, AC	1
Bertram, EH; Fernandez, EJ; Lothman, EW; Strauss, I; Williamson, JM	1
Chaudhri, G; Hunt, NH; Moore, DE; Sanni, LA; Stocker, R; Tattam, BN; Thomas, SR	1
Cleaves, HJ; Miller, SL	1
Feligioni, M; Pattarini, R; Pittaluga, A; Raiteri, M	1
Baraldi, M; Cannazza, G; Zanoli, P	1
Akita, M; Hashimoto, T; Katoh, A; Uenohara, K	1
Cohen, Y; Melamed, E; Offen, D; Sadan, O; Shemesh, N	1
Bennouar, KE; Beurrier, C; Bonvento, G; Escartin, C; Faideau, M; Gubellini, P; Kerkerian-Le Goff, L	1
Couté, Y; Ollagnier de Choudens, S; Reichmann, D	1
Booker, SJ; Esakova, OA; Grove, TL; McLaughlin, MI; Saunders, AH; Silakov, A; Yennawar, NH	1
Ealick, SE; Fenwick, MK	1
Robertson, DS	1

Reviews

4 review(s) available for aspartic acid and quinolinic acid

Article	Year
Quinolinic acid and kynurenic acid in the mammalian brain. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Brain Diseases; Dioxygenases; Epilepsy, Temporal Lobe; Glutamates; Glutamic Acid; Humans; Kynurenic Acid; Kynurenine; Lyases; Nerve Degeneration; Oxygenases; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, Neurotransmitter; Transaminases	1991
Neurochemical correlates to selective neuronal vulnerability. Progress in brain research, 1985, Volume: 63 Topics: Adenosine; Afferent Pathways; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Calcium; Chlorides; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoglycemia; Models, Biological; Neural Inhibition; Neurochemistry; Neurons; Neurotransmitter Agents; Norepinephrine; Parasympathomimetics; Quinolinic Acid; Quinolinic Acids; Rats	1985
Endogenous excitotoxic agents. Ciba Foundation symposium, 1987, Volume: 126 Topics: Animals; Aspartic Acid; Cell Survival; Central Nervous System; Dementia; Epilepsy; Glutamates; Glutamic Acid; Humans; Huntington Disease; Models, Neurological; Neurons; Quinolinic Acid; Quinolinic Acids	1987
Excitatory receptors and their role in excitotoxicity. Biochemical Society transactions, 1987, Volume: 15, Issue:2 Topics: Aminobutyrates; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Humans; N-Methylaspartate; Neurons; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1987

Other Studies

55 other study(ies) available for aspartic acid and quinolinic acid

Article	Year
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists. Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8 Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1992
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Neurochemical characterization of excitotoxin lesions in the cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1991
Quinolinic acid is a potent lipid peroxidant in rat brain homogenates. Neurochemical research, 1991, Volume: 16, Issue:10 Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Malondialdehyde; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Thiobarbiturates	1991
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity. Science (New York, N.Y.), 1990, Mar-23, Volume: 247, Issue:4949 Pt 1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium Channels; Drug Antagonism; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Mice; N-Methylaspartate; Neurons; Nifedipine; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse (New York, N.Y.), 1989, Volume: 3, Issue:1 Topics: Animals; Aspartic Acid; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptide Y; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Somatostatin	1989
N-methyl-D-aspartate-sensitive [3H]glutamate binding sites in brain synaptic membranes treated with Triton X-100. Biochimica et biophysica acta, 1989, Jun-15, Volume: 1012, Issue:1 Topics: Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Kinetics; Kynurenic Acid; N-Methylaspartate; Octoxynol; Polyethylene Glycols; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes; Temperature; Tissue Distribution	1989
Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists. Brain research, 1988, Apr-19, Volume: 446, Issue:2 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Aspartic Acid; Cells, Cultured; Corpus Striatum; Embryo, Mammalian; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1988
Paradoxical convulsant action of a novel non-competitive N-methyl-D-aspartate (NMDA) antagonist, tiletamine. Brain research, 1988, Oct-04, Volume: 461, Issue:2 Topics: Animals; Anticonvulsants; Aspartic Acid; Cyclohexanes; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex, Monosynaptic; Seizures; Tiletamine	1988
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist? Brain research, 1985, Jun-10, Volume: 336, Issue:1 Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism	1985
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin	1986
[Effect of excitant amino acid antagonists on glutamate receptors in the locust and on convulsions induced by glutamate, aspartate, kynurenine and quinolinic acid in mice]. Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:3 Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Glutamic Acid; Grasshoppers; Kynurenine; Male; Membrane Potentials; Mice; Muscles; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures	1986
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine	1986
Effects of topically applied excitatory amino acids on evoked potentials and single cell activity in rat cerebral cortex. European journal of pharmacology, 1986, Mar-04, Volume: 121, Issue:3 Topics: Administration, Topical; Amino Acids; Animals; Aspartic Acid; Carbachol; Cerebral Cortex; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tetrodotoxin	1986
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science (New York, N.Y.), 1986, Oct-03, Volume: 234, Issue:4772 Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1986
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices. Brain research, 1986, Aug-27, Volume: 381, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1986
The effect of kainic, quinolinic and beta-kainic acids on the release of endogenous amino acids from rat brain slices. Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1986
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation. Neuroscience letters, 1987, Mar-31, Volume: 75, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine	1987
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons. Science (New York, N.Y.), 1987, May-01, Volume: 236, Issue:4801 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc	1987
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus. Neuroscience letters, 1987, Jul-22, Volume: 78, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1987
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors. Journal of neurochemistry, 1987, Volume: 49, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin	1987
The mouse neocortical slice: preparation and responses to excitatory amino acids. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 88, Issue:1 Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Cerebral Cortex; Corpus Callosum; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred Strains; N-Methylaspartate; Ouabain; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Tetrodotoxin	1987
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro. British journal of pharmacology, 1988, Volume: 93, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine	1988
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo. British journal of pharmacology, 1988, Volume: 93, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1988
Kynurenic acid and AP5 distinguish between NMDA receptor agonists. Experimental neurology, 1988, Volume: 102, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine	1988
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors	1988
Neuropharmacological actions of kynurenic and quinolinic acids on horizontal cells of the isolated fish retina. Brain research, 1986, Aug-20, Volume: 380, Issue:2 Topics: Animals; Aspartic Acid; Cobalt; Cyprinidae; Evoked Potentials, Visual; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Photic Stimulation; Pyridines; Quinolinic Acid; Quinolinic Acids; Retina	1986
Acute tachycardia and pressor effects following injections of kainic acid into the antero-dorsal medial hypothalamus. Neuropharmacology, 1987, Volume: 26, Issue:6 Topics: Animals; Aspartic Acid; Blood Pressure; Heart Rate; Hypothalamus; Injections; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains	1987
Quinolinate mimics neurotoxic actions of N-methyl-D-aspartate in rat cerebellar slices. Neuroscience letters, 1987, Aug-18, Volume: 79, Issue:1-2 Topics: Animals; Aspartic Acid; Cerebellum; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats	1987
Interactions between topically applied excitatory amino acids on rat cerebral cortex: discrimination by pentobarbitone. Experimental brain research, 1987, Volume: 68, Issue:3 Topics: Administration, Topical; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Oxadiazoles; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains	1987
The action of quinolinate in the rat spinal cord in vitro. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:12 Topics: Animals; Anticonvulsants; Aspartic Acid; Convulsants; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord	1987
Quinolinic acid stimulates luteinizing hormone secretion through a serotonin-dependent mechanism. Experimental brain research, 1985, Volume: 59, Issue:1 Topics: Animals; Aspartic Acid; Castration; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; Norepinephrine; Pituitary Gland, Anterior; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission	1985
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents. Neuroscience letters, 1987, Jan-14, Volume: 73, Issue:2 Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Muscle Relaxants, Central; N-Methylaspartate; Oxadiazoles; Piperazines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Time Factors	1987
Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2 Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Kainic Acid; Levorphanol; Mice; Morphinans; N-Methylaspartate; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1987
In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures. Journal of neurochemistry, 1985, Volume: 45, Issue:2 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Electroencephalography; gamma-Aminobutyric Acid; Glutamine; Glycine; Hippocampus; Humans; Injections, Intraventricular; Male; Niacin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Taurine	1985
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat. Neuroscience letters, 1984, May-04, Volume: 46, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine	1984
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain research, 1982, Sep-09, Volume: 247, Issue:1 Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Convulsants; Drug Interactions; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Niacinamide; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats	1982
Actions of excitatory amino acids and kynurenic acid in the primate hippocampus: a preliminary study. Neuroscience letters, 1984, Dec-21, Volume: 52, Issue:3 Topics: Amino Acids; Animals; Aspartic Acid; Callitrichinae; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1984
Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2 Topics: Animals; Aspartic Acid; Central Nervous System; Evoked Potentials; Glutamates; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Pyrrolidinones; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface	1983
Effects of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones. The Journal of physiology, 1983, Volume: 339 Topics: 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Female; Glutamates; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate	1983
In vivo release of [3H]-purines by quinolinic acid and related compounds. British journal of pharmacology, 1983, Volume: 80, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium	1983
Evidence for the malate aspartate shuttle in pancreatic islets. Archives of biochemistry and biophysics, 1982, Volume: 213, Issue:2 Topics: Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; Aspartic Acid; Insulin; Islets of Langerhans; Malates; Malonates; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tissue Distribution	1982
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum. Neuroscience, 1993, Volume: 52, Issue:4 Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine	1993
Histological and 1H magnetic resonance spectroscopic imaging analysis of quinolinic acid-induced damage to the rat striatum. Magnetic resonance in medicine, 1997, Volume: 37, Issue:1 Topics: Animals; Aspartic Acid; Cell Count; Cell Survival; Chromatography, High Pressure Liquid; Corpus Striatum; Magnetic Resonance Spectroscopy; Male; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity	1997
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria. The American journal of pathology, 1998, Volume: 152, Issue:2 Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Female; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Malaria; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Osmolar Concentration; Oxidation-Reduction; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase	1998
The nicotinamide biosynthetic pathway is a by-product of the RNA world. Journal of molecular evolution, 2001, Volume: 52, Issue:1 Topics: Aspartic Acid; Dihydroxyacetone; Dihydroxyacetone Phosphate; Glyceraldehyde; Glyceraldehyde 3-Phosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; NAD; Niacin; Quinolinic Acid; RNA	2001
N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition. Journal of neurochemistry, 2001, Volume: 76, Issue:1 Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; HIV Envelope Protein gp120; Hydrogen-Ion Concentration; Male; N-Methylaspartate; Norepinephrine; Piperidines; Protein Kinase C; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptosomes; Zinc	2001
Prenatal exposure to methyl mercury in rats: focus on changes in kynurenine pathway. Brain research bulletin, 2001, May-15, Volume: 55, Issue:2 Topics: Animals; Aspartic Acid; Female; Fetus; Glutamic Acid; Hippocampus; Kynurenine; Mercury Poisoning, Nervous System; Methylmercury Compounds; Neurons; ortho-Aminobenzoates; Pregnancy; Prenatal Exposure Delayed Effects; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan	2001
Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid. Plant physiology, 2006, Volume: 141, Issue:3 Topics: Amino Acid Oxidoreductases; Arabidopsis; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Multienzyme Complexes; NAD; Pentosyltransferases; Plastids; Quinolinic Acid	2006
Longitudinal MRI and MRSI characterization of the quinolinic acid rat model for excitotoxicity: peculiar apparent diffusion coefficients and recovery of N-acetyl aspartate levels. NMR in biomedicine, 2010, Volume: 23, Issue:2 Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Nervous System Diseases; Quinolinic Acid; Rats; Rats, Wistar	2010
Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake. PloS one, 2010, Jan-01, Volume: 5, Issue:1 Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Ciliary Neurotrophic Factor; Corpus Striatum; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Neurons; Quinolinic Acid; Rats	2010
Dual activity of quinolinate synthase: triose phosphate isomerase and dehydration activities play together to form quinolinate. Biochemistry, 2015, Oct-27, Volume: 54, Issue:42 Topics: Aspartic Acid; Bacterial Proteins; Dihydroxyacetone Phosphate; Metabolic Networks and Pathways; Models, Chemical; Multienzyme Complexes; NAD; Quinolinic Acid; Thermotoga maritima; Triose-Phosphate Isomerase	2015
Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid. Journal of the American Chemical Society, 2016, 06-15, Volume: 138, Issue:23 Topics: Aspartic Acid; Binding Sites; Catalysis; Dihydroxyacetone Phosphate; Models, Molecular; Multienzyme Complexes; Protein Conformation; Pyrococcus horikoshii; Quinolinic Acid	2016
Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate. Biochemistry, 2016, 08-02, Volume: 55, Issue:30 Topics: Archaeal Proteins; Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Dihydroxyacetone Phosphate; Iron-Sulfur Proteins; Models, Molecular; Multienzyme Complexes; Protein Conformation; Pyrococcus horikoshii; Quinolinic Acid	2016
Proposed biochemistry of Parkinson's and Alzheimer's diseases. Medical hypotheses, 2017, Volume: 109 Topics: Aldehydes; Alzheimer Disease; Aspartic Acid; Betaine; Brain; Disease Progression; Humans; Kynurenine; Lewy Bodies; Models, Biological; Parkinson Disease; Plaque, Amyloid; Pyruvaldehyde; Quinolinic Acid; Treatment Outcome	2017