Page last updated: 2024-08-17

aspartic acid and quinazolines

aspartic acid has been researched along with quinazolines in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Donsback, RC; Sirotnak, FM1
Bertino, JR; Chello, PL; DeAngelis, LM; McQueen, CA1
O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE1
Maley, F; Maley, GF1
Albrecht, AM; Hutchison, DJ1
Donsbach, RC; Sirotnak, FM1
Gröger, D; Johne, S; Waiblinger, K1
Albrecht, AM; Biedler, JL; Hutchison, DJ; Spengler, BA1
Asquith, RS; Rivett, DE1
Biermann, D; Finer-Moore, J; Michelitsch, MD; Nissen, R; Sage, CR; Stout, TJ; Stroud, RM1
Brenk, R; Diederich, F; Garcia, GA; Klebe, G; Meyer, EA; Reuter, K; Stubbs, MT1
Alzani, R; Ciomei, M; Degrassi, A; Fanti, S; Giusti, AM; Nanni, C; Patton, V; Pesenti, E; Russo, M; Texido, G1
Masuya, T; Miyoshi, H; Morisaka, H; Murai, M1
Capoferri, L; Lodola, A; Mor, M; Rivara, S1
Aburaya, S; Aoki, W; Inaoka, H; Masuya, T; Miyoshi, H; Murai, M1
Jansch, A; Lamantia, T; Marsee, JD; Miller, JM; Weiland, MH1

Other Studies

16 other study(ies) available for aspartic acid and quinazolines

ArticleYear
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Aminopterin; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Chick Embryo; DNA, Neoplasm; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Quinazolines; Sarcoma 180; Tetrahydrofolate Dehydrogenase; Time Factors

1975
Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Cancer research, 1976, Volume: 36, Issue:7 PT 1

    Topics: Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Folic Acid Antagonists; Kinetics; Leukocytes; Methotrexate; Methyltransferases; Quinazolines; Temperature; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase; Triazines

1976
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
    Journal of neurochemistry, 1992, Volume: 58, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines

1992
The apparent induction of thymidylate synthetase by amethopterin.
    Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

    Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Methotrexate; Methyltransferases; Neoplasms, Experimental; Quinazolines; Rats; Thymine Nucleotides; Uracil Nucleotides

1971
Folate reductase of the amethopterin-resistant Streptococcus faecium var. durans-Ak. I. Inhibition by amethopterin and methasquin, a new quinazoline antifolate.
    Molecular pharmacology, 1970, Volume: 6, Issue:4

    Topics: Aspartic Acid; Chromatography, DEAE-Cellulose; Electrophoresis; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Molecular Weight; NADP; Potassium Chloride; Quinazolines; Streptococcus; Tetrahydrofolate Dehydrogenase

1970
Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Aminopterin; Animals; Antineoplastic Agents; Ascitic Fluid; Aspartic Acid; Benzoates; Binding, Competitive; Biological Transport, Active; Cell Line; Cells, Cultured; Diffusion; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Quinazolines; Streptococcus pneumoniae; Temperature; Tetrahydrofolate Dehydrogenase; Time Factors; Tritium

1972
[Studies on biosynthesis of the quinazoline alkaloid peganin in Adhatoda vasica Nees].
    Die Pharmazie, 1973, Volume: 28, Issue:6

    Topics: Alkaloids; Aspartic Acid; Carbon Isotopes; Plants, Medicinal; Pyrrolidines; Quinazolines

1973
Drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant Chinese hamster cells in vitro.
    Cancer research, 1972, Volume: 32, Issue:1

    Topics: Animals; Aspartic Acid; Benzoates; Cell Line; Chromosome Aberrations; Cricetinae; Drug Resistance; Folic Acid Antagonists; In Vitro Techniques; Karyotyping; Methotrexate; Pharmacogenetics; Quinazolines; Tetrahydrofolate Dehydrogenase

1972
Studies on the photooxidation of tryptophan.
    Biochimica et biophysica acta, 1971, Volume: 252, Issue:1

    Topics: Amino Acids; Ammonia; Aspartic Acid; Chromatography, Thin Layer; Electrophoresis, Paper; Formates; Hydrochloric Acid; Kinetics; Kynurenine; Light; Models, Structural; Nitrogen; Oxygen; Photolysis; Quinazolines; Radiation Effects; Tryptophan; Water

1971
D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine.
    Biochemistry, 1998, Sep-29, Volume: 37, Issue:39

    Topics: Asparagine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Escherichia coli; Fluorodeoxyuridylate; Folic Acid; Hydrogen Bonding; Imidazoles; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Quinazolines; Substrate Specificity; Tetrahydrofolates; Thymidylate Synthase

1998
Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening.
    Journal of molecular biology, 2004, Apr-16, Volume: 338, Issue:1

    Topics: Aspartic Acid; Binding Sites; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Databases, Factual; Drug Design; Enzyme Inhibitors; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Pentosyltransferases; Quinazolines; Structure-Activity Relationship; Zymomonas

2004
Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Antineoplastic Agents; Aspartic Acid; Cyclin-Dependent Kinases; Diagnostic Imaging; Disease Models, Animal; Drug Evaluation, Preclinical; Genes, ras; Glycine; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Mutant Proteins; Pyrazoles; Quinazolines; Treatment Outcome

2010
Pinpoint chemical modification of Asp160 in the 49 kDa subunit of bovine mitochondrial complex I via a combination of ligand-directed tosyl chemistry and click chemistry.
    Biochemistry, 2014, Dec-16, Volume: 53, Issue:49

    Topics: Acetogenins; Animals; Aspartic Acid; Benzoates; Catalytic Domain; Cattle; Click Chemistry; Electron Transport Complex I; Enzyme Inhibitors; Furans; Indicators and Reagents; Ligands; Mitochondria, Heart; Models, Molecular; Molecular Weight; NADH Dehydrogenase; Protein Conformation; Protein Subunits; Pyrazoles; Quinazolines; Tosyl Compounds

2014
Quantum mechanics/molecular mechanics modeling of covalent addition between EGFR-cysteine 797 and N-(4-anilinoquinazolin-6-yl) acrylamide.
    Journal of chemical information and modeling, 2015, Mar-23, Volume: 55, Issue:3

    Topics: Acrylamides; Aspartic Acid; Catalytic Domain; Cysteine; ErbB Receptors; Models, Molecular; Molecular Dynamics Simulation; Protein Conformation; Quantum Theory; Quinazolines

2015
Specific Methylation of Asp160 (49 kDa subunit) Located inside the Quinone Binding Cavity of Bovine Mitochondrial Complex I.
    Biochemistry, 2016, 06-14, Volume: 55, Issue:23

    Topics: Animals; Aspartic Acid; Binding Sites; Catalytic Domain; Cattle; Electron Transport; Electron Transport Complex I; Enzyme Inhibitors; Ligands; Methylation; Mitochondria, Heart; Protein Conformation; Protein Subunits; Quinazolines; Quinones; Tosyl Compounds

2016
Engineered Sphingomonas sp. KT-1 PahZ1 monomers efficiently degrade poly(aspartic acid).
    Biophysical chemistry, 2022, Volume: 281

    Topics: Aspartic Acid; Nitro Compounds; Peptides; Quinazolines; Sphingomonas

2022