aspartic acid has been researched along with oxadiazoles in 271 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 237 (87.45) | 18.7374 |
| 1990's | 32 (11.81) | 18.2507 |
| 2000's | 1 (0.37) | 29.6817 |
| 2010's | 1 (0.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brocklehurst, K; Shipton, M; Stuchbury, T | 1 |
| Davies, J; Evans, RH; Francis, AA; Watkins, JC | 1 |
| Albuquerque, EX; Alkondon, M; Aronstam, RS; Costa, AC; Radhakrishnan, V | 1 |
| Lanthorn, TH; Monaghan, DT; Watson, GB | 1 |
| Brackley, P; Goodnow, R; Nakanishi, K; Sudan, HL; Usherwood, PN | 1 |
| Dichter, M; Morad, M; Tang, CM | 1 |
| Finch, DM; Fisher, RS; Jackson, MB | 1 |
| Church, J; Lodge, D | 1 |
| Grudt, TJ; Jahr, CE | 1 |
| Glaum, SR; Miller, RJ; Scholz, WK | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Nistri, A; Sivilotti, L; Welsh, DM | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Raigorodsky, G; Urca, G | 2 |
| Kimura, F; Nishigori, A; Tsumoto, T | 1 |
| Cotman, CW; Krause, JD; Nangel-Taylor, K; Palmer, E; Roxas, A | 1 |
| Ikeda, H; Kay, CD; Robbins, J | 2 |
| Colpaert, FC; Koek, W | 1 |
| Costa, E; Eimerl, S; Schramm, M | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Dutton, GR; Philibert, RA; Rogers, KL | 1 |
| Osborne, NN | 1 |
| Keith, RA; Klika, AB; Mangano, TJ; Patel, J; Salama, AI; Zinkand, WC | 1 |
| Boksa, P; Kohn-Alexander, J; Mount, H; Quirion, R | 1 |
| De Montigny, C; Debonnel, G; Junien, JL; Monnet, FP | 1 |
| Berrino, L; Loffreda, A; Maione, S; Marmo, E; Matera, MG; Vitagliano, S | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Masetto, S; Prigioni, I; Russo, G; Valli, P | 1 |
| Herreras, O; Martín del Río, R; Menéndez, N; Sánchez Herranz, A; Solís, JM | 1 |
| Godfraind, JM | 1 |
| Barolet, AW; Baskys, A; Bernstein, NK; Carlen, PL | 1 |
| Erdö, SL; Michler, A | 1 |
| de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 2 |
| Michl, J; Ujec, E; Vlachová, V; Vyklický, L; Vyskocil, F | 1 |
| Aanonsen, LM; Wilcox, GL | 3 |
| Fischbach, GD; O'Brien, RJ | 1 |
| Jordan, W; Sutor, B; Zieglgänsberger, W | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Bean, BP; Huettner, JE | 1 |
| Dudel, J; Franke, C; Hatt, H; Ramsey, RL; Usherwood, PN | 1 |
| Cull-Candy, SG; Howe, JR; Ogden, DC | 1 |
| Bennett, MV; Kushner, L; Lerma, J; Zukin, RS | 1 |
| Lovinger, DM; Weight, FF; White, G | 1 |
| Garthwaite, G; Garthwaite, J | 4 |
| Gruol, DL; Joels, M; Yool, AJ | 1 |
| Cull-Candy, SG; Gallo, V; Usowicz, MM | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Kuhn, D; Mayer, ML; Sernagor, E; Vyklicky, L | 1 |
| Gallo, V; Giovannini, C; Levi, G | 1 |
| Jope, RS; Li, X | 1 |
| Alho, H; Barbaccia, ML; Costa, E; Szekely, AM | 1 |
| Backus, KH; Kettenmann, H; Schachner, M | 1 |
| Salt, TE | 1 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Iwasaki, M | 1 |
| Cotman, CW; Monaghan, DT; Palmer, E | 2 |
| Buckley, KS; Collins, GG | 1 |
| Barish, ME; Sands, SB | 1 |
| de Montigny, C; Debonnel, G; Weiss, M | 1 |
| Caspary, DM; Faingold, CL | 1 |
| Bauce, L; Kemp, DE; Weiss, S | 1 |
| Ito, M; Karachot, L | 1 |
| Ito, I; Sugiyama, H; Watanabe, M | 1 |
| McCaslin, PP; Morgan, WW | 2 |
| Gallo, V; Giovannini, C; Levi, G; Suergiu, R | 2 |
| Fonnum, F; Syvertsen, C | 1 |
| Araneda, R; Bustos, G | 1 |
| Clow, DW; Jhamandas, K | 1 |
| O'Dell, TJ | 1 |
| Ogita, K; Yoneda, Y | 2 |
| Cha, JH; Greenamyre, JT; Hollingsworth, ZR; Young, AB | 1 |
| Guiramand, J; Nourigat, A; Recasens, M; Sassetti, I | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Abbott, NJ; Hassan, S; Lieberman, EM | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Baba, A; Iwata, H; Kihara, T; Sawada, T | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| King, AE; Thompson, SW | 1 |
| Ben-Ari, Y; Represa, A; Tremblay, E | 1 |
| Crépel, F; Hicks, TP; Krupa, M | 1 |
| Akoev, GN; Andrianov, IuN; Bromm, B; Sabo, T; Sherman, NO | 1 |
| Guiramand, J; Recasens, M; Sassetti, I | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Herranz, AS; Herreras, O; Martín del Río, R; Menéndez, N; Solis, JM | 1 |
| Miyachi, E; Murakami, M | 1 |
| Dubinsky, JM; Rothman, SM; Yamada, KA | 1 |
| Anis, NA; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Konno, K; Miledi, R; Ragsdale, D | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Bieger, D; Hashim, MA | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Hornfeldt, CS; Larson, AA | 1 |
| Smith, SS | 2 |
| Sato, H; Yamamoto, C | 1 |
| Arenson, MS; Nistri, A | 1 |
| Arenson, MS; King, A; Nistri, A | 1 |
| Aryanpur, JJ; Cole, AE; Eccles, CU; Fisher, RS | 1 |
| Bingmann, D; Speckmann, EJ; Walden, J | 1 |
| Barrington, M; Ehrlich, D; Sattayasai, J; Zappia, J | 1 |
| Jones, MW; Kilpatrick, IC; Phillipson, OT | 1 |
| Talman, WT | 1 |
| Johnston, MV; McDonald, JW; Silverstein, FS; Uckele, J | 1 |
| Bustos, G; Rudolph, MI | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Drejer, J; Honoré, T | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS | 1 |
| Heinemann, U; Köhr, G | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Meldrum, BS; Millan, MH; Patel, S | 1 |
| Harrison, NL; Simmonds, MA | 1 |
| Christensen, BN; Hals, G; Shingai, R | 1 |
| Collins, JF; Meldrum, BS; Turski, L | 1 |
| Homma, S | 1 |
| Higashima, M; Sawada, S; Yamamoto, C | 1 |
| Goldberg, O; Teichberg, VI | 2 |
| Davies, J; Quinlan, JE | 1 |
| Baba, A; Iwata, H; Morimoto, H | 1 |
| Chuang, DM; Costa, E; Iadarola, MJ; Meek, JL; Nicoletti, F; Roth, BL | 1 |
| Lodge, D; Martin, D | 1 |
| Hablitz, JJ | 1 |
| Martin, MR | 2 |
| Campochiaro, P; Coyle, JT; Ferkany, JW | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Costa, E; Iadarola, MJ; Nicoletti, F; Wroblewski, JT | 1 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 2 |
| Gregersen, H; McLennan, H; Peet, MJ | 1 |
| Drejer, J; Honoré, T; Meier, E; Schousboe, A | 1 |
| Cha, JH; Dowling, JE; O'Brien, DR | 1 |
| Jürgens, U; Richter, K | 1 |
| Crepel, F; Gardette, R | 1 |
| Bobbin, RP; Jenison, GL; Winbery, S | 1 |
| Cuenod, M; Do, KQ; Herrling, PL; Streit, P; Turski, WA | 1 |
| Choi, DW; Koh, JY; Peters, S | 2 |
| Cross, A; Skan, W; Slater, P | 1 |
| King, AE; Nistri, A | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Mayer, ML; Westbrook, GL | 2 |
| Choi, DW; Koh, J; Peters, S | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 2 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Morgan, IG | 1 |
| Gulat-Marnay, C; Lafitte, A; Schwartz, JC; Vargas, F | 1 |
| Bockaert, J; Kemp, DE; Schmidt, BH; Sebben, M; Sladeczek, F; Weiss, S | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Crepel, F; Debono, M; Hamon, B | 1 |
| Grantyn, R; Hablitz, JJ; Lux, HD; Perouansky, M | 1 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Greenamyre, JT; Olson, JM; Penney, JB; Young, AB | 2 |
| Benavides, J; Carter, C; Fage, D; Scatton, B | 1 |
| Alho, H; Costa, E; Eva, C; Fadda, E; Nicoletti, F; Wroblewski, JT | 1 |
| Crepel, F; Gardette, R; Krupa, M | 1 |
| Fischbach, GD; Thio, LL; Trussell, LO; Zorumski, CF | 2 |
| Dryer, SE | 1 |
| Engberg, I; Flatman, JA; Nedergaard, S | 1 |
| Sheardown, MJ | 1 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Canonico, PL; Catania, MV; Favit, A; Nicoletti, F | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Shreve, PE; Uretsky, NJ | 1 |
| Ben-Ari, Y; Cherubini, E; Gho, M; Neuman, RS | 1 |
| Davidoff, RA; Hackman, JC; Wohlberg, CJ | 1 |
| Davidson, N; Fong, TM; Lester, HA | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Massey, SC; Miller, RF | 1 |
| Farley, JM; Huang, HM; Jin, C; Rockhold, RW | 1 |
| Addae, JI; Stone, TW | 1 |
| Anand, H; Badman, G; Collins, JF; Dixon, AJ; Roberts, PJ | 1 |
| Blake, J; Church, J; Davies, SN; Jacobson, AE; Lessor, RA; Lodge, D; Rice, KC | 1 |
| Nauta, HJ; Pisharodi, M | 1 |
| Meldrum, B | 1 |
| Herrling, PL; Klockgether, T; Sontag, KH; Turski, L; Watkins, JC | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Wohlberg, CJ | 1 |
| Evans, RH; Evans, SJ; Pook, PC; Sunter, DC | 1 |
| Choi, DW; Goldberg, MP; Kim, JP | 1 |
| Card, JP; Siman, R | 1 |
| Besharse, JC; Spratt, G | 1 |
| Akaike, N; Carpenter, DO; Hori, N | 1 |
| McLarnon, JG; Quastel, DM | 1 |
| Hamon, B; Heinemann, U | 2 |
| Ebina, Y; Shingai, R | 1 |
| Bunch, ST; Dunnett, SB; Jones, GH; Whishaw, IQ | 1 |
| Carpenter, DO; Galeno, T; Hori, N | 1 |
| Ehrlich, D; Sattayasai, J | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Church, J; Davies, SN; Lodge, D | 1 |
| Garthwaite, G; Garthwaite, J; Yamini, B | 1 |
| Miller, RJ; Murphy, SN; Thayer, SA | 1 |
| Blake, JC; Church, J; Davies, SN; Lodge, D; Martin, D | 1 |
| Agrawal, SG; Evans, RH | 1 |
| Garthwaite, G; Garthwaite, J; Hajós, F | 1 |
| Connick, JH; Heywood, GC; Smith, DA; Stone, TW | 1 |
| Heinemann, U; Mody, I | 1 |
| Kurcewicz, I; Louvel, J; Pumain, R | 1 |
| Heinemann, U | 1 |
| De Kloet, ER; Joëls, M; Urban, IJ; Van Veldhuizen, M | 1 |
| Kato, S; Negishi, K; Teranishi, T | 1 |
| Chapman, AG; Hart, GP; Meldrum, BS; Turski, L; Watkins, JC | 1 |
| Biscoe, TJ; Burton, NR; Duchen, MR | 1 |
| Dunnett, SB; Hastings, MH; Winn, P | 1 |
| Allen, G; Lowe, G | 1 |
| Berry, SC; Dawkins, SL; Lodge, D | 1 |
| Evans, RH; Watkins, JC | 1 |
| Watkins, JC | 1 |
| Evans, RH; Smith, DA | 1 |
| Donaldson, PL; Duce, IR; Usherwood, PN | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Donzanti, BA; Uretsky, NJ | 3 |
| Kamp, CW; Morgan, WW | 1 |
| Collingridge, GL; Kehl, SJ; Loo, R; McLennan, H | 1 |
| Neal, M | 1 |
| Joëls, M; Urban, IJ | 2 |
| Ariel, M; Dowling, JE; Lasater, EM; Mangel, SC | 1 |
| Agnati, LF; Celani, MF; Fuxe, K; Martire, M; Zini, I; Zoli, M | 1 |
| McLennan, H | 2 |
| Crepel, F; Dupont, JL; Fournier, E; Gardette, R | 1 |
| Anis, NA; Berry, SC; Lodge, D | 1 |
| Arenson, MS; Berti, C; King, AE; Nistri, A | 1 |
| Fagg, GE; Matus, A | 1 |
| Perkins, MN; Stone, TW | 4 |
| Hill, RG; Salt, TE | 1 |
| MacDonald, JF; Porietis, AV | 1 |
| Herrling, PL; Morris, R; Salt, TE | 1 |
| Dale, N; Roberts, A | 1 |
| Yazulla, S | 1 |
| Ayoub, GS; Lam, DM | 1 |
| Crunelli, V; Mayer, ML | 1 |
| Jones, AW; Smith, DA; Watkins, JC | 1 |
| Stone, TW | 1 |
| Crepel, F; Dhanjal, SS; Sears, TA | 1 |
| Davies, J; Evans, RH; Francis, AA; Jones, AW; Watkins, JC | 1 |
| Blaney, FE; Davies, S; Duckworth, DM; Gaster, LM; Hagan, JJ; Ham, P; Hatcher, J; Jenkins, S; Jennings, AJ; Joiner, GF; Jones, BJ; King, FD; Middlemiss, DN; Mulholland, KR; Price, GW; Riley, G; Roberts, C; Routledge, C; Selkirk, J; Slade, PD; Wyman, PA | 1 |
| Fulcrand, P; Hamzé, A; Hernandez, JF; Martinez, J | 1 |
| Fukushima, T; Ge, D; Ishii, K; Nabeshima, T; Song, Z; Toriumi, K; Watanabe, H; Yamada, H | 1 |
2 review(s) available for aspartic acid and oxadiazoles
| Article | Year |
|---|---|
The physiology of excitatory amino acids in the vertebrate central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Central Nervous System; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Vertebrates | 1987 |
Pharmacology of excitatory amino acid transmitters.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate | 1981 |
269 other study(ies) available for aspartic acid and oxadiazoles
| Article | Year |
|---|---|
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole as a reactivity probe for the investigation of the thiol proteinases. evidence that ficin and bromelain may lack carboxyl groups conformationally equivalent to that of aspartic acid-158 of papain.
Topics: 4-Chloro-7-nitrobenzofurazan; Alkylation; Aspartic Acid; Binding Sites; Bromelains; Endopeptidases; Ficain; Hydrogen-Ion Concentration; Kinetics; Oxadiazoles; Papain | 1976 |
Excitatory amino acid receptors and synaptic excitation in the mammalian central nervous system.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Spinal Nerve Roots | 1979 |
Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead.
Topics: Animals; Aspartic Acid; Calcium; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Conductivity; Glycine; Hippocampus; Ion Channels; Kainic Acid; Lead; Learning Disabilities; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Selective activation of oscillatory currents by trans-ACPD in rat brain mRNA-injected Xenopus oocytes and their blockade by NMDA.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cycloleucine; Ion Channels; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus | 1990 |
Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA.
Topics: Amino Acids; Animals; Aspartic Acid; Bee Venoms; Brain; Chickens; Kainic Acid; Male; Membrane Potentials; Microinjections; N-Methylaspartate; Neurotoxins; Oocytes; Oxadiazoles; Poly A; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spermine; Wasp Venoms; Xenopus | 1990 |
Modulation of the N-methyl-D-aspartate channel by extracellular H+.
Topics: Animals; Aspartic Acid; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Hydrogen-Ion Concentration; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Miniature excitatory synaptic currents in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Aspartic Acid; Calcium Channel Blockers; Cells, Cultured; Dipeptides; Electrophysiology; Fetus; Hippocampus; Kinetics; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Synapses; Tetrodotoxin | 1990 |
Failure of sigma-receptor ligands to reduce the excitatory actions of N-methyl-DL-aspartate on rat spinal neurons in-vivo.
Topics: Animals; Aspartic Acid; Haloperidol; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Stereoisomerism | 1990 |
Quisqualate activates N-methyl-D-aspartate receptor channels in hippocampal neurons maintained in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Electric Stimulation; Glycine; Hippocampus; Indoles; Ion Channel Gating; N-Methylaspartate; Neural Conduction; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Acute- and long-term glutamate-mediated regulation of [Ca++]i in rat hippocampal pyramidal neurons in vitro.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
An electrophysiological study of the action of N-methyl-D-aspartate on excitatory synaptic transmission in the optic tectum of the frog in vitro.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electrophysiology; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rana temporaria; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Synapses; Synaptic Transmission | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
Spinal antinociceptive effects of excitatory amino acid antagonists: quisqualate modulates the action of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesics; Animals; Aspartic Acid; Dipeptides; Electric Stimulation; Glutamine; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Vocalization, Animal | 1990 |
Contribution of quisqualate/kainate and NMDA receptors to excitatory synaptic transmission in the rat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Electrophysiology; Evoked Potentials; Kainic Acid; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, Neurotransmitter; Visual Cortex | 1990 |
Changes in excitatory amino acid modulation of phosphoinositide metabolism during development.
Topics: Aging; Animals; Aspartic Acid; Brain; Inositol Phosphates; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Excitatory amino acid receptors on sustained retinal ganglion cells in the kitten during the critical period of development.
Topics: Action Potentials; Aging; Animals; Aspartic Acid; Cats; Kainic Acid; N-Methylaspartate; Oxadiazoles; Photic Stimulation; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Visual Pathways | 1990 |
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; Kainic Acid; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Phencyclidine; Pyrrolidinones; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate.
Topics: Animals; Anticonvulsants; Aspartic Acid; Blood; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Cytoplasmic Granules; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Piperazines; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Veratridine | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
Glutamate receptor agonists cause efflux of endogenous neuroactive amino acids from cerebellar neurons in culture.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Stimulatory and inhibitory actions of excitatory amino acids on inositol phospholipid metabolism in rabbit retina. Evidence for a specific quisqualate receptor subtype associated with neurones.
Topics: Animals; Aspartic Acid; Calcium; Carbachol; Dose-Response Relationship, Drug; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, AMPA; Receptors, Neurotransmitter; Retina | 1990 |
6,7-Dinitroquinoxaline-2,3-dione blocks the cytotoxicity of N-methyl-D-aspartate and kainate, but not quisqualate, in cortical cultures.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Hippocampus; Kainic Acid; Ligands; N-Methylaspartate; Neurotoxins; Norepinephrine; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Subtypes of excitatory amino acid receptors involved in the stimulation of [3H]dopamine release from cell cultures of rat ventral mesencephalon.
Topics: Animals; Aspartic Acid; Cells, Cultured; Dopamine; Kynurenic Acid; Magnesium; Mesencephalon; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors.
Topics: Animals; Aspartic Acid; Guanidines; Haloperidol; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spiperone | 1990 |
Excitatory amino acids and cardiovascular apparatus: experimental studies on conscious rats with L-glutamate, N-methyl-D-aspartate, kainate and quisqualate.
Topics: Amino Acids; Animals; Aspartic Acid; Cardiovascular Physiological Phenomena; Cardiovascular System; Glutamates; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Synaptic Transmission | 1990 |
Glutamate-receptor-mediated regulation of the cytoplasmic free calcium level in cultured cerebellar granule cells.
Topics: Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cytoplasm; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Pre- and postsynaptic excitatory action of glutamate agonists on frog vestibular receptors.
Topics: Afferent Pathways; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana esculenta; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Vestibule, Labyrinth | 1990 |
Role of endogenous taurine on the glutamate analogue-induced neurotoxicity in the rat hippocampus in vivo.
Topics: Animals; Aspartic Acid; Extracellular Space; Hippocampus; Kainic Acid; N-Methylaspartate; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Sucrose; Taurine | 1990 |
Microionophoretic study with milacemide, a glycine precursor, on mammalian central nervous system cells.
Topics: Acetamides; Animals; Aspartic Acid; Brain; Cats; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Kainic Acid; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid | 1990 |
NMDA and quisqualate reduce a Ca-dependent K+ current by a protein kinase-mediated mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aspartic Acid; Calcium; Enzyme Inhibitors; Hippocampus; Isoquinolines; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Protein Kinases; Quisqualic Acid; Rats; Rats, Inbred F344; Second Messenger Systems | 1990 |
GABA does not protect cerebro-cortical cultures against excitotoxic cell death.
Topics: Animals; Aspartic Acid; Cell Survival; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Oxadiazoles; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
Neuropeptide Y selectively potentiates N-methyl-D-aspartate-induced neuronal activation.
Topics: Animals; Aspartic Acid; Drug Synergism; Haloperidol; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Neuropeptide Y; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
Kainic acid responses and toxicity show pronounced Ca2+ dependence.
Topics: Animals; Aspartic Acid; Calcium; Drug Interactions; In Vitro Techniques; Ion Channels; Iontophoresis; Kainic Acid; Limbic System; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1985 |
Evidence that excitatory amino acids not only activate the receptor channel complex but also lead to use-dependent block.
Topics: Amino Acids; Animals; Aspartic Acid; Chick Embryo; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Spinal Cord | 1986 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
Evidence for a magnesium-insensitive membrane resistance increase during NMDA-induced depolarizations in rat neocortical neurons in vitro.
Topics: Animals; Aspartic Acid; Cell Membrane; Electric Conductivity; Frontal Lobe; Glutamates; Glutamic Acid; Ion Channels; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1987 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
Topics: Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Ion Channels; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Visual Cortex | 1988 |
Rapid activation and desensitization by glutamate of excitatory, cation-selective channels in locust muscle.
Topics: Animals; Aspartic Acid; Cations; Glutamates; Glutamic Acid; Grasshoppers; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscles; Oxadiazoles; Quisqualic Acid | 1988 |
Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
N-methyl-D-aspartate activates different channels than do kainate and quisqualate.
Topics: Animals; Aspartic Acid; Brain Chemistry; Electric Conductivity; Female; Ion Channels; Kainic Acid; Magnesium; Male; N-Methylaspartate; Oocytes; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1989 |
Ethanol inhibits NMDA-activated ion current in hippocampal neurons.
Topics: 1-Butanol; Aspartic Acid; Butanols; Calcium Channels; Chloride Channels; Chlorides; Electric Conductivity; Ethanol; gamma-Aminobutyric Acid; Hippocampus; Humans; Ion Channels; Kainic Acid; Membrane Proteins; Methanol; N-Methylaspartate; Neurons; Oxadiazoles; Pentanols; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels | 1989 |
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
Topics: Analgesia; Animals; Aspartic Acid; Baclofen; Behavior, Animal; Bicuculline; Kainic Acid; Male; Mice; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, GABA-A; Spinal Cord; Substance P | 1989 |
Differential dependence on Ca2+ of N-methyl-D-aspartate and quisqualate neurotoxicity in young rat hippocampal slices.
Topics: Animals; Aspartic Acid; Calcium; Cell Survival; Chlorides; Hippocampus; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Staining and Labeling | 1989 |
Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured purkinje neurons.
Topics: Action Potentials; Animals; Aspartic Acid; Cadmium; Calcium; Cations, Divalent; Choline; Electric Conductivity; Ion Channels; Kainic Acid; Kynurenic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Sucrose; Tetrodotoxin | 1989 |
Multiple conductance channels in type-2 cerebellar astrocytes activated by excitatory amino acids.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebellum; Convulsants; Electric Conductivity; Evoked Potentials; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Synaptic Transmission | 1989 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Open channel block of NMDA receptor responses evoked by tricyclic antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Aspartic Acid; Cells, Cultured; Convulsants; Desipramine; Embryo, Mammalian; Hippocampus; Ion Channels; Kinetics; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Quisqualic acid modulates kainate responses in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Interactions; Kainic Acid; Nitroprusside; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Inhibition of inositol phospholipid synthesis and norepinephrine-stimulated hydrolysis in rat brain slices by excitatory amino acids.
Topics: Animals; Aspartic Acid; Brain; Brain Mapping; Glutamates; In Vitro Techniques; Inositol; Inositol Phosphates; Male; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Receptors, Adrenergic, alpha | 1989 |
In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.
Topics: Animals; Aspartic Acid; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Gene Expression Regulation; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Phencyclidine; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Transcription, Genetic | 1989 |
Pharmacological characterization of the glutamate receptor in cultured astrocytes.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo.
Topics: Action Potentials; Animals; Aspartic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine; Thalamus | 1989 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Neurotoxicity of excitatory amino acid receptor agonists in young rat hippocampal slices.
Topics: Animals; Aspartic Acid; Female; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Time Factors | 1989 |
Effects of pentobarbitone, ketamine and lignocaine on synaptic transmission in the rat olfactory cortex in vitro.
Topics: Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Ketamine; Lidocaine; Male; N-Methylaspartate; Olfactory Pathways; Oxadiazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1989 |
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
A quantitative description of excitatory amino acid neurotransmitter responses on cultured embryonic Xenopus spinal neurons.
Topics: Animals; Aspartic Acid; Embryo, Nonmammalian; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus laevis | 1989 |
Properties of excitatory amino acid receptors on sustained ganglion cells in the cat retina.
Topics: Action Potentials; Animals; Aspartic Acid; Cats; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells | 1989 |
Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: further evidence that toxicity of domoic acid involves kainate receptor activation.
Topics: Animals; Aspartic Acid; Colchicine; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1989 |
Non-N-methyl-D-aspartate receptors may mediate ipsilateral excitation at lateral superior olivary synapses.
Topics: Acoustic Stimulation; Action Potentials; Animals; Aspartic Acid; Auditory Pathways; Chinchilla; Dose-Response Relationship, Drug; Functional Laterality; Kainic Acid; N-Methylaspartate; Olivary Nucleus; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Kainate evokes the release of endogenous glycine from striatal neurons in primary culture.
Topics: Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Long-term desensitization of quisqualate-specific glutamate receptors in Purkinje cells investigated with wedge recording from rat cerebellar slices.
Topics: Animals; Aspartic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Glutamate receptor subtypes may be classified into two major categories: a study on Xenopus oocytes injected with rat brain mRNA.
Topics: Animals; Aspartic Acid; Brain Chemistry; Electrophysiology; Glutamates; Homocysteine; Ibotenic Acid; Kainic Acid; Microinjections; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1989 |
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
Expression of excitatory amino acid receptors by cerebellar cells of the type-2 astrocyte cell lineage.
Topics: Animals; Aspartic Acid; Astrocytes; Autoradiography; Cell Line; Cerebellum; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
L-[3H]glutamate binding to a membrane preparation from crayfish muscle.
Topics: Animals; Aspartic Acid; Astacoidea; Binding, Competitive; Calcium; Cell Membrane; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Muscles; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism | 1989 |
Modulation of dendritic release of dopamine by N-methyl-D-aspartate receptors in rat substantia nigra.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dendrites; Dopamine; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substantia Nigra; Tetrodotoxin | 1989 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances.
Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Drug Contamination; Glutamates; Glutamic Acid; Oxadiazoles; Quisqualic Acid | 1989 |
K+ differentially affects the excitatory amino acids- and carbachol-elicited inositol phosphate formation in rat brain synaptoneurosomes.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Carbachol; Frontal Lobe; Glutamates; Glutamic Acid; Inositol Phosphates; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Sugar Phosphates; Synaptosomes | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Evidence that glutamate mediates axon-to-Schwann cell signaling in the squid.
Topics: Action Potentials; Animals; Aspartic Acid; Axons; Cell Communication; Convulsants; Decapodiformes; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Schwann Cells | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
Excitatory amino acids enhance dissociation of zinc from soluble protein in cytosol of rat hippocampus.
Topics: Amino Acids; Animals; Aspartic Acid; Cytosol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Tissue Proteins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Zinc | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
Characterization of deep dorsal horn neurones in the rat spinal cord in vitro: synaptic and excitatory amino acid induced excitations.
Topics: Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Synapses | 1989 |
Transient increase of NMDA-binding sites in human hippocampus during development.
Topics: Adult; Aging; Aspartic Acid; Fetus; Glutamates; Glutamic Acid; Hippocampus; Humans; Infant; Infant, Newborn; Middle Aged; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Selective effects of serotonin upon excitatory amino acid-induced depolarizations of Purkinje cells in cerebellar slices from young rats.
Topics: Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Serotonin | 1989 |
[Analysis of the effect of quisqualate, N-methyl-D- aspartate and several blockers of amino acid receptors on synaptic transmission in the ampullae of Lorenzini].
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Electric Fish; Evoked Potentials; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensory Receptor Cells; Skates, Fish; Synapses; Synaptic Transmission; Valine | 1989 |
Developmental changes in the chemosensitivity of rat brain synaptoneurosomes to excitatory amino acids, estimated by inositol phosphate formation.
Topics: Aging; Animals; Aspartic Acid; Carbachol; Female; Frontal Lobe; Glutamates; Glutamic Acid; Inositol Phosphates; Male; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Synaptosomes | 1989 |
Measurement of amino acid release from cultured cerebellar granule cells by an improved high performance liquid chromatography procedure.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine | 1989 |
Extracellular taurine increase in rat hippocampus evoked by specific glutamate receptor activation is related to the excitatory potency of glutamate agonists.
Topics: Action Potentials; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
Quantitative physiological characterization of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kainic Acid; Mathematics; N-Methylaspartate; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Synapses | 1989 |
Inhibition of rat brain glutamate receptors by philanthotoxin.
Topics: Animals; Aspartic Acid; Bee Venoms; Brain; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Wasp Venoms; Xenopus | 1989 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the neonatal rat hippocampus by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Carbachol; Chlorides; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol; Kainic Acid; Kinetics; Lithium; Lithium Chloride; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Excitatory amino acid receptor-mediated activation of solitarial deglutitive loci.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Deglutition; Dipeptides; Esophagus; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Pharynx; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Selective inhibition of excitatory amino acids by divalent cations. A novel means for distinguishing N-methyl-D-aspartic acid-, kainate- and quisqualate-mediated actions in the mouse spinal cord.
Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; Male; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord; Zinc | 1989 |
Quisqualate and N-methyl-D-aspartate synergistically excite cerebellar Purkinje cells as a long-term effect.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Female; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats | 1989 |
Some properties of ionic channels activated by excitatory amino acids in hippocampal neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Electric Stimulation; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Ion Channels; Manganese; Oxadiazoles; Quisqualic Acid | 1985 |
The effects of potassium channel blocking agents on the responses of in vitro frog motoneurones to glutamate and other excitatory amino acids: an intracellular study.
Topics: Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Ion Channels; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rana temporaria; Spinal Cord | 1985 |
Excitatory amino acid-induced responses of frog motoneurones bathed in low Na+ media: an intracellular study.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Sodium; Spinal Cord | 1985 |
Selective depression of N-methyl-D-aspartate-mediated responses by dextrorphan in the hippocampal slice in rat.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dextrorphan; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; Morphinans; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Augmentation of glutamate responses by GABA in the rat's motorcortex in vivo.
Topics: Animals; Aspartic Acid; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Motor Cortex; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Excitatory amino acids interfere with normal eye growth in posthatch chick.
Topics: Animals; Anterior Chamber; Aspartic Acid; Chickens; Eye; Kainic Acid; N-Methylaspartate; Organ Size; Oxadiazoles; Quisqualic Acid; Retina; Time Factors | 1989 |
Regulation of dopamine function in the nucleus accumbens of the rat by the thalamic paraventricular nucleus and adjacent midline nuclei.
Topics: Animals; Aspartic Acid; Dopamine; Electric Stimulation; Injections, Intraventricular; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Septal Nuclei; Thalamic Nuclei | 1989 |
Kynurenic acid microinjected into the nucleus tractus solitarius of rat blocks the arterial baroreflex but not responses to glutamate.
Topics: Acetylcholine; Animals; Arteries; Aspartic Acid; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Histocytochemistry; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Reflex | 1989 |
HA-966 (1-hydroxy-3-aminopyrrolidone-2) selectively reduces N-methyl-D-aspartate (NMDA)-mediated brain damage.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Diseases; Corpus Striatum; N-Methylaspartate; Oxadiazoles; Pyrrolidinones; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Estrogen administration increases neuronal responses to excitatory amino acids as a long-term effect.
Topics: Action Potentials; Animals; Aspartic Acid; Estradiol; Female; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats | 1989 |
Cultured cerebellar cells as an in vitro model of excitatory amino acid receptor function.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Models, Neurological; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Narcotics; Nociceptors; Oxadiazoles; Pain; Phencyclidine; Phentolamine; Quisqualic Acid; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1987 |
Functional and biochemical characteristics of a putative quisqualate-type receptor in rat striatum: effect of brain lesions.
Topics: Animals; Aspartic Acid; Brain; Cerebral Cortex; Convulsants; Corpus Striatum; Dopamine; Glutamates; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1986 |
NMDA-receptors on Purkinje cell dendrites in guinea pig cerebellar slices.
Topics: Animals; Aspartic Acid; Dendrites; Guinea Pigs; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
New quinoxalinediones show potent antagonism of quisqualate responses in cultured mouse cortical neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Drug; Sodium | 1988 |
N-methyl-D-aspartate (NMDA) receptors control respiratory off-switch in cat.
Topics: Action Potentials; Animals; Aspartic Acid; Cats; Dibenzocycloheptenes; Dizocilpine Maleate; Iontophoresis; Ketamine; N-Methylaspartate; Oxadiazoles; Phencyclidine; Phrenic Nerve; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiration; Respiratory Center | 1988 |
Differences in magnesium and calcium effects on N-methyl-D-aspartate- and quisqualate-induced decreases in extracellular sodium concentration in rat hippocampal slices.
Topics: Action Potentials; Animals; Aspartic Acid; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium | 1988 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Oxadiazoles; Pilocarpine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Seizures | 1988 |
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1985 |
Excitatory effects of L-glutamate and some analogs on isolated horizontal cells from the catfish retina.
Topics: Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Retina | 1985 |
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist?
Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism | 1985 |
Effects of bath-applied excitatory amino acids and their analogs on spinal interneurons of the lamprey.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; Glycine; Homocysteine; In Vitro Techniques; Interneurons; Kainic Acid; Lampreys; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord | 1985 |
Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.
Topics: Animals; Aspartic Acid; Drug Synergism; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Synaptic Transmission | 1985 |
Peptides derived from kainic acid as antagonists of N-methyl-D-aspartate-induced neuroexcitation in rat brain.
Topics: Animals; Aspartic Acid; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1985 |
Excitatory and inhibitory responses of Purkinje cells, in the rat cerebellum in vivo, induced by excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Neurochemical relation between excitatory and inhibitory amino acids in hippocampus.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains | 1985 |
Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus.
Topics: Animals; Aspartic Acid; Calcium; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Male; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord | 1986 |
A dipeptide derived from kainic and L-glutamic acids: a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Corpus Striatum; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Picrotoxin; Quisqualic Acid; Rats; Seizures; Sodium | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
Excitatory amino acid analogs evoke release of endogenous amino acids and acetyl choline from chick retina in vitro.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Calcium; Chickens; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Sodium; Stimulation, Chemical | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors.
Topics: Age Factors; Aminobutyrates; Animals; Aspartic Acid; Drug Interactions; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Norepinephrine; Oxadiazoles; Oxazoles; Phosphatidylinositols; Phosphoserine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Amino Acid; Receptors, Cell Surface | 1986 |
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine | 1986 |
2-Amino-5-phosphonovalerate and Co2+ selectively block depolarization and burst firing of rat hippocampal CA1 pyramidal neurones by N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cobalt; Evoked Potentials; Hippocampus; Iontophoresis; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Tetrodotoxin; Valine | 1986 |
Pharmacologically distinct glutamate receptors on cerebellar granule cells.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1986 |
Effects of D-aspartate on excitatory amino acid-induced release of [3H]GABA from goldfish retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Goldfish; Kainic Acid; Oxadiazoles; Quisqualic Acid; Retina; Tritium | 1986 |
A comparative study on the elicitability of vocalization by electrical brain stimulation, glutamate, aspartate and quisqualate in the squirrel monkey.
Topics: Animals; Aspartic Acid; Brain Mapping; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Reaction Time; Saimiri; Vocalization, Animal | 1986 |
Receptors for excitatory amino acids on neurons in rat pyriform cortex.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Limbic System; N-Methylaspartate; Olfactory Pathways; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
Chemoresponsiveness of intracellular nuclei neurones to L-aspartate, L-glutamate and related derivatives in rat cerebellar slices maintained in vitro.
Topics: Animals; Aspartic Acid; Cerebellar Nuclei; Convulsants; Glutamates; Glutamic Acid; In Vitro Techniques; Injections; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Comparative actions of quisqualate and N-methyl-D-aspartate, excitatory amino acid agonists, on guinea-pig cochlear potentials.
Topics: Action Potentials; Animals; Aspartic Acid; Cochlea; Dose-Response Relationship, Drug; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Vestibulocochlear Nerve | 1986 |
In vitro release and electrophysiological effects in situ of homocysteic acid, an endogenous N-methyl-(D)-aspartic acid agonist, in the mammalian striatum.
Topics: Animals; Aspartic Acid; Calcium; Cats; Caudate Nucleus; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Synergism; Electric Stimulation; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Homocysteine; Iontophoresis; Oxadiazoles; Potassium; Quisqualic Acid; Rana temporaria; Rats; Veratrine | 1986 |
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid | 1986 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Localization of [3H]glutamate binding sites in rat adrenal medulla.
Topics: Acetates; Acetic Acid; Adrenal Medulla; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Organ Specificity; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1986 |
Blockade by D-aminophosphonovalerate or Mg2+ of excitatory amino acid-induced responses on spinal motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Synaptic Transmission; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
AMPA is a powerful neurotoxin in the chicken retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body | 1987 |
Formation and utilization of the active sulfate donor [35S]3'-phosphoadenosine 5'-phosphosulfate in brain slices: effects of depolarizing agents.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Cerebral Cortex; Glutamates; Glutamic Acid; Kinetics; Male; Naphthols; Nitrophenols; Oxadiazoles; Phosphoadenosine Phosphosulfate; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Sulfates; Sulfur Radioisotopes; Veratridine; Veratrine | 1987 |
Dual action of excitatory amino acids on the metabolism of inositol phosphates in striatal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Carbachol; Cells, Cultured; Corpus Striatum; Glutamates; Inositol Phosphates; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Sugar Phosphates; Valine | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Voltage-dependency of the responses of cerebellar Purkinje cells to excitatory amino acids.
Topics: Action Potentials; Animals; Aspartic Acid; Cadmium; Glutamates; Glutamic Acid; Membrane Potentials; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1987 |
Glutamate-induced ionic currents in cultured neurons from the rat superior colliculus.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Superior Colliculi | 1987 |
The mouse neocortical slice: preparation and responses to excitatory amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Cerebral Cortex; Corpus Callosum; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred Strains; N-Methylaspartate; Ouabain; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Tetrodotoxin | 1987 |
Glutamate receptor subtypes in cultured cerebellar neurons: modulation of glutamate and gamma-aminobutyric acid release.
Topics: Animals; Aspartic Acid; Calcium; Cations; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium | 1987 |
Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse.
Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Cerebellum; Glutamates; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Colchicine; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Differential effects of serotonin on the spontaneous discharge and on the excitatory amino acid-induced responses of deep cerebellar nuclei neurons in rat cerebellar slices.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellar Nuclei; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Excitatory amino acid-evoked membrane currents and excitatory synaptic transmission in lamprey reticulospinal neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Stem; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Lampreys; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Spinal Cord; Synapses; Synaptic Transmission | 1988 |
The modulation of excitatory amino acid responses by serotonin in the cat neocortex in vitro.
Topics: Animals; Aspartic Acid; Cats; Cerebral Cortex; Cinanserin; Electric Stimulation; Evoked Potentials; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Methysergide; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Serotonin; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
A new and specific non-NMDA receptor antagonist, FG 9065, blocks L-AP4-evoked depolarization in rat cerebral cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
L-glutamate-induced depolarization in solitary photoreceptors: a process that may contribute to the interaction between photoreceptors in situ.
Topics: Animals; Aspartic Acid; Axons; Dose-Response Relationship, Drug; Electric Conductivity; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid; Sodium; Turtles | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures.
Topics: Animals; Aspartic Acid; Carbachol; Cerebellum; Diglycerides; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; N-Methylaspartate; Neurons; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sphingosine; Tetradecanoylphorbol Acetate | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1988 |
Epinephrine and norepinephrine modulate neuronal responses to excitatory amino acids and agonists in frog spinal cord.
Topics: Amino Acids; Animals; Aspartic Acid; Epinephrine; Glutamates; Glutamic Acid; In Vitro Techniques; Isoproterenol; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rana pipiens; Reference Values; Spinal Cord; Yohimbine | 1987 |
Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus laevis | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Lithium; Lithium Chloride; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1988 |
Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells | 1988 |
Acute tachycardia and pressor effects following injections of kainic acid into the antero-dorsal medial hypothalamus.
Topics: Animals; Aspartic Acid; Blood Pressure; Heart Rate; Hypothalamus; Injections; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains | 1987 |
Interactions between topically applied excitatory amino acids on rat cerebral cortex: discrimination by pentobarbitone.
Topics: Administration, Topical; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Oxadiazoles; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains | 1987 |
The action of quinolinate in the rat spinal cord in vitro.
Topics: Animals; Anticonvulsants; Aspartic Acid; Convulsants; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites.
Topics: Animals; Aspartic Acid; Autoradiography; Brain; Brain Mapping; Calcium; Cerebellum; Chlorides; Glutamates; Hippocampus; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1985 |
Excitatory amino acid pharmacology of the auditory nerve and nucleus magnocellularis of the chicken.
Topics: Amino Acids; Animals; Aspartic Acid; Auditory Pathways; Baclofen; Brain Stem; Chick Embryo; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Vestibulocochlear Nerve | 1985 |
Novel kainic acid analogues. Effects on cyclic GMP content of adult rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship | 1986 |
In vitro neurotoxicity of excitatory acid analogues during cerebellar development.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Female; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1986 |
Is Metaphit a phencyclidine antagonist? Studies with ketamine, phencyclidine and N-methylaspartate.
Topics: Action Potentials; Animals; Aspartic Acid; Depression, Chemical; Drug Interactions; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1986 |
An animal model for neuron-specific spinal cord lesions by the microinjection of N-methylaspartate, kainic acid, and quisqualic acid.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Forelimb; Ganglia, Spinal; Hindlimb; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission | 1985 |
Excitatory amino acid antagonists as novel anticonvulsants.
Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Glutamates; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship | 1986 |
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Muscle Relaxants, Central; N-Methylaspartate; Oxadiazoles; Piperazines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Time Factors | 1987 |
After-hyperpolarizations produced in frog motoneurons by excitatory amino acid analogues.
Topics: 2,4-Dinitrophenol; Animals; Aspartic Acid; Dinitrophenols; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Ouabain; Oxadiazoles; Potassium; Quisqualic Acid; Ranidae; Sodium; Synaptic Transmission | 1987 |
A comparison of excitatory amino acid antagonists acting at primary afferent C fibres and motoneurones of the isolated spinal cord of the rat.
Topics: Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1987 |
High concentrations of naloxone attenuate N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Female; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Naloxone; Nervous System Diseases; Oxadiazoles; Pregnancy; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
Excitatory amino acid neurotoxicity in the hippocampal slice preparation.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Microscopy, Electron; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
Excitatory amino acids and rod photoreceptor disc shedding: analysis using specific agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Light; N-Methylaspartate; Oxadiazoles; Phagosomes; Photoreceptor Cells; Pigment Epithelium of Eye; Quisqualic Acid; Rana pipiens; Xenopus laevis | 1988 |
Piriform cortex brain slices: techniques for isolation of synaptic inputs.
Topics: Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Dendrites; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Synapses | 1988 |
A voltage clamp study of the glutamate responsive neuromuscular junction in Drosophila melanogaster.
Topics: Action Potentials; Alcohols; Amino Acids; Animals; Aspartic Acid; Drosophila melanogaster; Electrodes; Glutamates; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid | 1988 |
Developmental changes in neuronal sensitivity to excitatory amino acids in area CA1 of the rat hippocampus.
Topics: Action Potentials; Aging; Animals; Aspartic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
Some properties of membrane current fluctuations induced by kainate, quisqualate, and NMDA in cultured septal neurons of rat.
Topics: Animals; Aspartic Acid; Brain; Cells, Cultured; Convulsants; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats | 1988 |
Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats.
Topics: Acetylcholinesterase; Amino Acids; Animals; Aspartic Acid; Basal Ganglia; Behavior, Animal; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Female; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substantia Innominata | 1987 |
Responses of pyriform cortex neurons to excitatory amino acids: voltage dependence, conductance changes, and effects of divalent cations.
Topics: Animals; Aspartic Acid; Brain; Cations, Divalent; Convulsants; Electric Stimulation; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats | 1987 |
Folic acid protects chick retinal neurons against the neurotoxic action of excitatory amino acids.
Topics: Animals; Aspartic Acid; Chickens; Dose-Response Relationship, Drug; Folic Acid; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acids; Quisqualic Acid; Retina | 1987 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Non-pharmacological effects of the use of microelectrophoresis and pressure ejection of drugs in combination.
Topics: Amino Acids; Animals; Aspartic Acid; Electrophoresis; Ibotenic Acid; Kainic Acid; Microelectrodes; N-Methylaspartate; Neurons; Nifedipine; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord | 1987 |
Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Convulsants; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats | 1987 |
The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Corpus Striatum; Glutamates; In Vitro Techniques; Kainic Acid; Magnesium; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Permeability; Quisqualic Acid | 1987 |
2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA).
Topics: Anesthetics; Anesthetics, Dissociative; Animals; Anura; Aspartic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Medulla Oblongata; N-Methylaspartate; Neurons; Oxadiazoles; Phenylpropanolamine; Quisqualic Acid; Rats; Spinal Cord | 1986 |
The primary afferent depolarizing action of kainate in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Aspartic Acid; Capsaicin; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Oxadiazoles; Quisqualic Acid; Rats; Spinal Nerve Roots | 1986 |
Amino acid neurotoxicity: relationship to neuronal depolarization in rat cerebellar slices.
Topics: Age Factors; Animals; Aspartic Acid; Cerebellar Diseases; Female; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Ouabain; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Veratridine | 1986 |
O-phosphohomoserine, a naturally occurring analogue of phosphonate amino acid antagonists, is an N-methyl-D-aspartate (NMDA) antagonist in rat hippocampus.
Topics: Animals; Aspartic Acid; Drug Interactions; Evoked Potentials; Hippocampus; Homoserine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1986 |
Laminar profiles of the changes in extracellular calcium concentration induced by repetitive stimulation and excitatory amino acids in the rat dentate gyrus.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Electric Stimulation; Hippocampus; Iontophoresis; Male; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1986 |
Effects of GABA and bicuculline on N-methyl-D-aspartate- and quisqualate-induced reductions in extracellular free calcium in area CA1 of the hippocampal slice.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Drug Interactions; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1986 |
Long-term alterations in amino acid-induced ionic conductances in chronic epilepsy.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cobalt; Electric Conductivity; Epilepsy; Glutamates; Kainic Acid; Motor Cortex; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Sodium | 1986 |
Excitatory amino acids and epilepsy-induced changes in extracellular space size.
Topics: Animals; Aspartic Acid; Cats; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuroglia; Oxadiazoles; Potassium; Quisqualic Acid; Somatosensory Cortex; Water-Electrolyte Balance | 1986 |
N-acetyl-aspartylglutamate: binding sites and excitatory action in the dorsolateral septum of rats.
Topics: Action Potentials; Animals; Aspartic Acid; Autoradiography; Binding Sites; Dipeptides; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Septal Nuclei | 1987 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Kainic Acid; Mice; Mice, Inbred DBA; Mice, Inbred Strains; N-Methylaspartate; Oxadiazoles; Piperazines; Pyrrolidines; Quinolinic Acids; Quisqualic Acid; Seizures | 1985 |
An intracellular study of the interactions of N-methyl-DL-aspartate with ketamine in the mouse hippocampal slice.
Topics: Action Potentials; Animals; Aspartic Acid; Drug Interactions; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxadiazoles; Quisqualic Acid | 1985 |
Neurotoxic amino acid lesions of the lateral hypothalamus: a parametric comparison of the effects of ibotenate, N-methyl-D,L-aspartate and quisqualate in the rat.
Topics: Animals; Aspartic Acid; Dopamine; Hypothalamic Area, Lateral; Ibotenic Acid; Male; Mesencephalon; N-Methylaspartate; Neural Pathways; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Investigation of the active site of papain with fluorescent probes.
Topics: Aspartic Acid; Binding Sites; Cysteine; Dioxins; Disulfides; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Nitro Compounds; Oxadiazoles; Papain; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Comparison of sigma- and kappa-opiate receptor ligands as excitatory amino acid antagonists.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cats; Cyclazocine; Ethylketocyclazocine; Kainic Acid; Ketamine; Ligands; Microelectrodes; N-Methylaspartate; Neurons; Oxadiazoles; Phenazocine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, sigma; Stereoisomerism | 1984 |
Pharmacological antagonists of excitant amino acid action.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Drug; Structure-Activity Relationship | 1981 |
Effect of urethane on synaptic and amino acid-induced excitation in isolated spinal cord preparations.
Topics: Animals; Aspartic Acid; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Ranidae; Rats; Spinal Cord; Synapses; Urethane | 1982 |
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system.
Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission | 1983 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
Effects of excitatory amino acids on locomotor activity after bilateral microinjection into the rat nucleus accumbens: possible dependence on dopaminergic mechanisms.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Septal Nuclei; Synaptic Transmission | 1983 |
Effects of excitatory amino acids on dopamine synthesis in the rat retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dopamine; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Retina | 1983 |
Voltage clamp analysis of the effect of excitatory amino acids and derivatives on Purkinje cell dendrites in rat cerebellar slices maintained in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Culture Techniques; Dendrites; Glutamates; Glutamic Acid; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission | 1983 |
Effects of kainic and other amino acids on synaptic excitation in rat hippocampal slices: 1. Extracellular analysis.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Evoked Potentials; Folic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Rats | 1983 |
Transmitter interactions in the rabbit retina.
Topics: Acetylcholine; Animals; Aspartic Acid; Atropine; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Retina | 1983 |
Amino acid neurotransmission between fimbria-fornix fibers and neurons in the lateral septum of the rat: a microiontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Iontophoresis; Male; N-Methylaspartate; Nerve Fibers; Neural Pathways; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Septal Nuclei; Synaptic Transmission; Valine | 1984 |
On the sensitivity of H1 horizontal cells of the carp retina to glutamate, aspartate and their agonists.
Topics: Animals; Aspartic Acid; Carps; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Retina | 1984 |
l-Glutamate reduces the affinity of [3H]N-propylnorapomorphine binding sites in striatal membranes.
Topics: Animals; Antiparkinson Agents; Apomorphine; Aspartic Acid; Binding Sites; Cell Membrane; Corpus Striatum; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Spiperone | 1984 |
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine | 1984 |
Effect of excitatory amino acids on Purkinje cell dendrites in cerebellar slices from normal and staggerer mice.
Topics: Amino Acids; Animals; Aspartic Acid; Crosses, Genetic; Dendrites; Glutamates; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Neurologic Mutants; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid | 1984 |
The effect of the dioxolanes on amino acid induced excitation in the mammalian spinal cord.
Topics: Animals; Aspartic Acid; Cats; Dioxolanes; Dioxoles; Kainic Acid; Ketamine; N-Methylaspartate; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Species Specificity; Spinal Cord; Stereoisomerism; Structure-Activity Relationship | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
The effect of D-alpha-aminoadipate on excitatory amino acid responses recorded intracellularly from motoneurones of the frog spinal cord.
Topics: 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Anterior Horn Cells; Aspartic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Spinal Nerve Roots | 1984 |
Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Chlorides; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Membranes | 1984 |
Arginine-vasopressin enhances the responses of lateral septal neurons in the rat to excitatory amino acids and fimbria-fornix stimuli.
Topics: Amino Acids; Animals; Arginine Vasopressin; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses | 1984 |
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Convulsants; Drug Interactions; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Niacinamide; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1982 |
Actions of excitatory amino acids and kynurenic acid in the primate hippocampus: a preliminary study.
Topics: Amino Acids; Animals; Aspartic Acid; Callitrichinae; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid | 1984 |
Differentiation of excitatory amino acid receptors in the rat caudal trigeminal nucleus: a microiontophoretic study.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Glutamates; Kainic Acid; Male; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Trigeminal Nuclei | 1982 |
DL-quisqualic and L-aspartic acids activate separate excitatory conductances in cultured spinal cord neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Fetus; Ion Channels; Membrane Potentials; Mice; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Stimulation, Chemical | 1982 |
Quisqualic acid excitation of cortical neurones is selectively antagonized by streptomycin.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Streptomycin; Synaptic Transmission | 1983 |
Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system.
Topics: Animals; Aspartic Acid; Central Nervous System; Evoked Potentials; Glutamates; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Pyrrolidinones; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1983 |
Effects of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones.
Topics: 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Female; Glutamates; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1983 |
Excitatory amino acid receptors in Xenopus embryo spinal cord and their role in the activation of swimming.
Topics: Animals; Aspartic Acid; Kainic Acid; Manganese; Membrane Potentials; Motor Activity; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Swimming; Xenopus | 1984 |
Stimulation of GABA release from retinal horizontal cells by potassium and acidic amino acid agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Goldfish; In Vitro Techniques; Kainic Acid; Oxadiazoles; Potassium; Quisqualic Acid; Retina | 1983 |
Antagonism of the hypermotility response induced by excitatory amino acids in the rat nucleus accumbens.
Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Aspartic Acid; Diaminopimelic Acid; Glutamates; Injections; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Septal Nuclei | 1984 |
Magnesium selectively inhibits N-methyl-aspartic acid-induced hypermotility after intra-accumbens injection.
Topics: Animals; Aspartic Acid; Calcium Chloride; Injections; Kainic Acid; Magnesium; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1984 |
Differential sensitivity of rat cerebellar cells in vitro to the neurotoxic effects of excitatory amino acid analogues.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; In Vitro Techniques; Interneurons; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats | 1984 |
The release of gamma-aminobutyric acid from horizontal cells of the goldfish (Carassius auratus) retina.
Topics: Animals; Aspartic Acid; Calcium; Cell Separation; Cobalt; Cyprinidae; Darkness; gamma-Aminobutyric Acid; Glutamates; Goldfish; In Vitro Techniques; Interneurons; Kainic Acid; Oxadiazoles; Potassium; Quisqualic Acid; Retina; Sodium; Time Factors | 1984 |
Mg2+ dependence of membrane resistance increases evoked by NMDA in hippocampal neurones.
Topics: Animals; Aspartic Acid; Cell Membrane; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats | 1984 |
Structure-activity relations of dipeptide antagonists of excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Dipeptides; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Structure-Activity Relationship | 1984 |
Actions of TRH and cyclo-(His-Pro) on spontaneous and evoked activity of cortical neurones.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Male; N-Methylaspartate; Neurons; Oxadiazoles; Peptides, Cyclic; Piperazines; Quisqualic Acid; Rats; Thyrotropin-Releasing Hormone | 1983 |
Effect of glutamate, aspartate and related derivatives on cerebellar purkinje cell dendrites in the rat: an in vitro study.
Topics: 2-Aminoadipic Acid; Action Potentials; Animals; Aspartic Acid; Dendrites; Glutamates; In Vitro Techniques; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains | 1982 |
Antagonism of excitatory amino acid-induced and synaptic excitation of spinal neurones by cis-2,3-piperidine dicarboxylate.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rana temporaria; Rats; Spinal Cord; Synapses | 1981 |
Methyltetrahydrofolate as an antagonist of excitatory amino acids on spinal neurones.
Topics: Amino Acids; Animals; Aspartic Acid; Folic Acid; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrahydrofolates | 1982 |
The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function b
Topics: Animals; Aspartic Acid; Autoreceptors; CHO Cells; Cricetinae; Frontal Lobe; Guinea Pigs; Humans; Hypothermia; In Vitro Techniques; Indoles; Male; Models, Molecular; Oxadiazoles; Piperazines; Piperidones; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Structure-Activity Relationship; Swine | 1998 |
Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral beta 3- and alpha-amino acids from Fmoc-protected aspartic acid.
Topics: Amino Acids; Aspartic Acid; Combinatorial Chemistry Techniques; Drug Design; Oxadiazoles | 2003 |
Determination of N-acetylaspartic acid concentration in the mouse brain using HPLC with fluorescence detection.
Topics: Animals; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Oxadiazoles; Proteins; Spectrometry, Fluorescence | 2012 |