aspartic acid has been researched along with naloxone in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (29.41) | 18.7374 |
| 1990's | 15 (44.12) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Gebhart, GF; Sherman, AD | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Ferraro, L; Morari, M; Nordberg, A; Spalluto, P; Tanganelli, S | 1 |
| Kangrga, I; Randić, M | 1 |
| Bishop, GA | 1 |
| Aricioğlu, F; Güngör, M; Koyuncuoğlu, H; Sağduyu, H | 1 |
| Bucholtz, DC; Ebling, FJ; Foster, DL; Karsch, FJ; Schall, RE; Suttie, JM; Vannerson, LA; Wood, RI | 1 |
| Ferin, M; Luckhaus, J; Reyes, A | 1 |
| Duranti, R; Wiesenfeld-Hallin, Z | 1 |
| DeLander, GE; Wahl, JJ | 1 |
| Enginar, N; Güngör, M; Hatipoğlu, I; Hizal, A; Koyuncuoğlu, H | 1 |
| Choi, DW; Goldberg, MP; Kim, JP | 1 |
| Choi, DW; Viseskul, V | 1 |
| Bell, RD; Cicero, TJ; Meyer, ER | 1 |
| Enginar, N; Hatipoğlu, I; Koyuncuoğlu, H | 1 |
| Badger, TM; Levenson, SE; Martin, JB; Millard, WJ; Rosenblum, PM | 1 |
| Cicero, TJ; Schainker, BA | 1 |
| Aslan, N; Berkman, K; Oktay, S; Onat, F; Toker, F | 1 |
| Aghajanian, GK; Kogan, JH; Moghaddam, B | 1 |
| Feng, Y; Ho, IK; Rockhold, RW; Zhang, T | 1 |
| Ho, IK; Hoshi, K; Ma, T | 1 |
| Gupta, MC; Singh, J | 1 |
| Contreras, E; Hernandez, L; Rada, P; Sepulveda, MJ; Tucci, S | 1 |
| Schlenker, EH | 1 |
| Chen, C; de Riel, JK; Li, JG; Liu-Chen, LY; Ozdener, F; Weinstein, H; Xu, W | 1 |
| Babey, AM; Cavalli, A; Loh, HH | 1 |
| Ananthanarayanan, VS; Zhorov, BS | 1 |
| Nakagawa, T | 1 |
| Chen, C; Huang, P; Li, J; Liu-Chen, LY; Visiers, I; Weinstein, H | 1 |
| Chen, JC; Huang, EY; Li, JY; Tan, PP; Wong, CH | 1 |
| Gelernter, J; Hernandez-Avila, CA; Kranzler, HR; Luo, X; Wand, G | 1 |
| Sharma, HS | 1 |
| Hsin, ST; Lin, FH; Lin, SL; Shen, CH; Tsai, RY; Wang, JJ; Wong, CS | 1 |
| Cherng, CH; Huang, HY; Lee, SO; Tao, PL; Wong, CS; Wu, CT; Yang, CP | 1 |
1 review(s) available for aspartic acid and naloxone
| Article | Year |
|---|---|
[Involvement of glial glutamate transporters in morphine dependence and naloxone-precipitated withdrawal].
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Excitatory Amino Acid Transporter 2; Gene Expression; Humans; Morphine Dependence; Naloxone; RNA, Messenger; Substance Withdrawal Syndrome | 2001 |
1 trial(s) available for aspartic acid and naloxone
| Article | Year |
|---|---|
Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1).
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Amino Acid Substitution; Analysis of Variance; Asparagine; Aspartic Acid; Female; Genotype; Humans; Hydrocortisone; Infusions, Intravenous; Male; Naloxone; Narcotic Antagonists; Polymorphism, Genetic; Receptors, Opioid, mu | 2003 |
32 other study(ies) available for aspartic acid and naloxone
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Morphine and pain: effects on aspartate, GABA and glutamate in four discrete areas of mouse brain.
Topics: Aminobutyrates; Animals; Aspartic Acid; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypothalamus; Male; Mice; Morphine; Naloxone; Pain; Reticular Formation; Stress, Physiological | 1976 |
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Mecamylamine; Methysergide; Naloxone; Nicotine; Receptors, GABA-A; Receptors, Nicotinic | 1991 |
Outflow of endogenous aspartate and glutamate from the rat spinal dorsal horn in vitro by activation of low- and high-threshold primary afferent fibers. Modulation by mu-opioids.
Topics: Afferent Pathways; Animals; Aspartic Acid; Capsaicin; Diterpenes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ganglia, Spinal; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Naloxone; Nerve Fibers; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Time Factors | 1991 |
Physiological interactions between enkephalin and excitatory amino acids in the cerebellar cortex of the opossum Didelphis marsupialis virginiana.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Drug Interactions; Electrophysiology; Enkephalins; Female; Glutamates; Glutamic Acid; Iontophoresis; Male; Naloxone; Opossums; Purkinje Cells | 1991 |
Intensification and attenuation of morphine dependence by D-aspartic acid and PLG.
Topics: Animals; Asparaginase; Aspartic Acid; Brain; Mice; Mice, Inbred BALB C; Morphine Dependence; MSH Release-Inhibiting Hormone; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1990 |
Metabolic interfaces between growth and reproduction. III. Central mechanisms controlling pulsatile luteinizing hormone secretion in the nutritionally growth-limited female lamb.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Female; Food Deprivation; Gonadotropin-Releasing Hormone; Growth Disorders; Hypothalamus, Middle; Luteinizing Hormone; Median Eminence; N-Methylaspartate; Naloxone; Preoptic Area; Sheep | 1990 |
Unexpected inhibitory action of N-methyl-D,L-aspartate or luteinizing hormone release in adult ovariectomized rhesus monkeys: a role of the hypothalamic-adrenal axis.
Topics: Animals; Aspartic Acid; Circadian Rhythm; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Immune Sera; Luteinizing Hormone; Macaca mulatta; N-Methylaspartate; Naloxone; Ovariectomy; Pituitary-Adrenal System; Reference Values | 1990 |
D-Arg1, D-Trp7,9, Leu11-substance P (spantide) does not antagonize substance P-induced hyperexcitability of the nociceptive flexion withdrawal reflex in the rat.
Topics: Afferent Pathways; Animals; Aspartic Acid; Evoked Potentials; Glutamates; Glutamic Acid; Injections, Spinal; Naloxone; Nociceptors; Physical Stimulation; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Morphine (intracerebroventricular) activates spinal systems to inhibit behavior induced by putative pain neurotransmitters.
Topics: Animals; Aspartic Acid; Behavior, Animal; Dose-Response Relationship, Drug; Male; Methysergide; Mice; Morphine; N-Methylaspartate; Naloxone; Neurotransmitter Agents; Nociceptors; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Serotonin; Spinal Cord; Substance P | 1989 |
Brain asparaginase, ACE activity and plasma cortisol level in morphine dependent rats: effect of aspartic acid and naloxone.
Topics: Animals; Asparaginase; Aspartic Acid; Brain; Hydrocortisone; Male; Morphine; Naloxone; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1986 |
High concentrations of naloxone attenuate N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Female; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Naloxone; Nervous System Diseases; Oxadiazoles; Pregnancy; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
Opioids and non-opioid enantiomers selectively attenuate N-methyl-D-aspartate neurotoxicity on cortical neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Indicators and Reagents; Methadone; Mice; Morphine; N-Methylaspartate; Naloxone; Narcotics; Neurons; Stereoisomerism | 1988 |
Characterization and possible opioid modulation of N-methyl-D-aspartic acid induced increases in serum luteinizing hormone levels in the developing male rat.
Topics: Aging; Animals; Aspartic Acid; Endorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Morphine; N-Methylaspartate; Naloxone; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains | 1988 |
The effect of morphine, naloxone, D- and L-aspartic acid on the brain and lung ACE in mice.
Topics: Animals; Aspartic Acid; Brain; In Vitro Techniques; Lung; Mice; Mice, Inbred Strains; Morphine; Naloxone; Peptidyl-Dipeptidase A; Stereoisomerism | 1983 |
Hypothalamic-pituitary function in adult rats treated neonatally with monosodium glutamate.
Topics: Animals; Animals, Newborn; Aspartic Acid; Castration; Glutamates; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; N-Methylaspartate; Naloxone; Rats; Sodium Glutamate | 1982 |
Acute central stimulation of luteinizing hormone by parenterally administered N-methyl-D,L-aspartic acid in the male rat.
Topics: Animals; Aspartic Acid; Castration; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Male; Naloxone; Pituitary Gland; Rats | 1980 |
Antinociceptive effect of D-aspartic acid in mice.
Topics: Analgesics; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Pain Measurement; Time Factors | 1995 |
Opiate withdrawal increases glutamate and aspartate efflux in the locus coeruleus: an in vivo microdialysis study.
Topics: Animals; Aspartic Acid; Drug Implants; Extracellular Space; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Microdialysis; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Naloxone-precipitated morphine withdrawal increases pontine glutamate levels in the rat.
Topics: Animals; Aspartic Acid; Dialysis; Drug Interactions; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Precipitated kappa-opioid receptor agonist withdrawal increase glutamate in rat locus coeruleus.
Topics: Analgesics; Analysis of Variance; Animals; Aspartic Acid; Benzeneacetamides; Butorphanol; Glutamic Acid; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Naloxone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1996 |
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine | 1997 |
Effect of precipitated withdrawal on extracellular glutamate and aspartate in the nucleus accumbens of chronically morphine-treated rats: an in vivo microdialysis study.
Topics: Animals; Aspartic Acid; Calcium; Extracellular Space; Glutamic Acid; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1998 |
Aspartic acid in the arcuate nucleus attenuates the depressive effects of naloxone on ventilation.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Hypercapnia; Hypoxia; Injections, Subcutaneous; Male; Microinjections; Naloxone; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Respiration; Sodium Chloride | 1998 |
Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptor.
Topics: Animals; Asparagine; Aspartic Acid; Binding Sites; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Kinetics; Mutagenesis, Site-Directed; Naloxone; Peptide Fragments; Peptides; Protein Structure, Secondary; Rats; Receptors, Opioid, mu; Somatostatin; Transfection | 1999 |
Altered adenylyl cyclase responsiveness subsequent to point mutations of Asp 128 in the third transmembrane domain of the delta-opioid receptor.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Substitution; Animals; Aspartic Acid; Binding, Competitive; Chlorocebus aethiops; Codon; Colforsin; COS Cells; Cyclic AMP; Diprenorphine; DNA, Complementary; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Ligands; Mice; Mutagenesis, Site-Directed; Naloxone; Pertussis Toxin; Point Mutation; Protein Binding; Receptors, Opioid, delta; Recombinant Fusion Proteins; Second Messenger Systems; Transfection; Virulence Factors, Bordetella | 1999 |
Homology models of mu-opioid receptor with organic and inorganic cations at conserved aspartates in the second and third transmembrane domains.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Aspartic Acid; Benzomorphans; Binding Sites; Cations; Cattle; Computer Simulation; Conserved Sequence; Fentanyl; Humans; Ligands; Metals; Models, Molecular; Molecular Sequence Data; Morphine; Naloxone; Narcotic Antagonists; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Opioid, mu; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2000 |
Functional role of a conserved motif in TM6 of the rat mu opioid receptor: constitutively active and inactive receptors result from substitutions of Thr6.34(279) with Lys and Asp.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Aspartic Acid; CHO Cells; Conserved Sequence; Cricetinae; Diprenorphine; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Lysine; Models, Molecular; Naloxone; Narcotic Antagonists; Pertussis Toxin; Rats; Receptors, Opioid, mu; Sulfur Radioisotopes; Threonine; Tritium; Virulence Factors, Bordetella | 2001 |
Dansyl-PQRamide, a possible neuropeptide FF receptor antagonist, induces conditioned place preference.
Topics: Animals; Aspartic Acid; Conditioning, Psychological; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Animal; Naloxone; Narcotic Antagonists; Neuropeptides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide | 2002 |
Hyperthermia influences excitatory and inhibitory amino acid neurotransmitters in the central nervous system. An experimental study in the rat using behavioural, biochemical, pharmacological, and morphological approaches.
Topics: Animals; Aspartic Acid; Behavior, Animal; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebrovascular Circulation; Cognition; Edema; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hyperthermia, Induced; Image Processing, Computer-Assisted; Male; Microscopy, Electron, Transmission; Motor Activity; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Rats; Rats, Wistar | 2006 |
Co-administration of ultra-low dose naloxone attenuates morphine tolerance in rats via attenuation of NMDA receptor neurotransmission and suppression of neuroinflammation in the spinal cords.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Aspartic Acid; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamic Acid; Injections, Spinal; Male; Morphine; Naloxone; Neuroglia; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 2010 |
Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Behavior, Animal; Disease Models, Animal; Down-Regulation; Drug Synergism; Glutamic Acid; Hyperalgesia; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Threshold; Posterior Horn Cells; Rats; Rats, Wistar; Reaction Time; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Sciatic Nerve; Sciatica; Time Factors; Tumor Necrosis Factor-alpha | 2013 |