aspartic acid has been researched along with morphine in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (50.94) | 18.7374 |
| 1990's | 8 (15.09) | 18.2507 |
| 2000's | 13 (24.53) | 29.6817 |
| 2010's | 4 (7.55) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Dowdy, EE; King, LJ; Minnema, KH | 1 |
| Canberk, A; Genç, E; Koyuncuoğlu, H; Sağduyu, H | 1 |
| Eroğlu, L; Genc, E; Güngör, M; Koyuncuoğlu, H; Sağduyu, H | 2 |
| Berkman, K; Genç, EM; Güngör, M; Keyer-Uysal, M; Koyuncuoğlu, H | 1 |
| Gebhart, GF; Sherman, AD | 1 |
| Orrego, F; Riveros, N | 1 |
| DeLander, GE; Wahl, JJ | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Enginar, N; Güngör, M; Hatipoğlu, I; Hizal, A; Koyuncuoğlu, H | 1 |
| Choi, DW; Viseskul, V | 1 |
| Chapman, AG | 1 |
| Bell, RD; Cicero, TJ; Meyer, ER | 1 |
| Anğ, O; Anğ-Küçüker, M; Güngör, M; Inanç, D; Koyuncuoğlu, H; Sağduyu, H; Uysal, V | 1 |
| Anğ, O; Güngör, M; Inanç, D; Koyuncouğlu, H; Sağduyu, H | 1 |
| Ali, BH; el Halawani, ME; Silsby, JL | 1 |
| Dostrovsky, J; Pomeranz, B | 1 |
| Harris, RL; Hawkins, RA; Miller, AL; Veech, RL | 1 |
| Eroğlu, L; Güngör, M; Koyuncuoğlu, H; Sağduyu, H | 1 |
| Bachelard, HS; Lindsay, JR | 1 |
| Enginar, N; Hatipoğlu, I; Koyuncuoğlu, H | 1 |
| Co, C; Freeman, ME; Lane, JD; Sands, MP; Smith, JE | 1 |
| Berkman, K; Hatipoğlu, I; Koyuncuoğlu, H; Sabuncu, H | 1 |
| Hepler, JR; Myers, RD; Noto, T | 1 |
| Berkman, K; Koyuncuŏglu, H; Matthaei, H; Wildmann, J | 1 |
| Aslan, N; Berkman, K; Oktay, S; Onat, F; Toker, F | 1 |
| Aghajanian, GK; Kogan, JH; Moghaddam, B | 1 |
| Feng, Y; Ho, IK; Rockhold, RW; Zhang, T | 1 |
| Bowery, NG; Fowler, LJ; Teoh, H | 1 |
| Gupta, MC; Singh, J | 1 |
| Contreras, E; Hernandez, L; Rada, P; Sepulveda, MJ; Tucci, S | 1 |
| Chen, C; de Riel, JK; DesJarlais, RL; Li, JG; Liu-Chen, LY; Matecka, D; Rice, K; Yin, J; Zhang, Y | 1 |
| Ananthanarayanan, VS; Zhorov, BS | 1 |
| Abarca, C; Contreras, E; Oliva, P; Sepúlveda, MJ; Silva, E | 1 |
| Coffman, BL; Goldsmith, S; Kearney, WR; Knosp, BM; Tephly, TR | 1 |
| Chang, YC; Cherng, CH; Tao, PL; Wang, JJ; Wen, ZH; Wong, CS | 1 |
| Contreras, E; Oliva, P; Sepúlveda, J | 1 |
| Minami, M; Nakagawa, T; Ozawa, T; Satoh, M; Sekiya, Y | 1 |
| Chang, YC; Wang, JJ; Wen, ZH; Wong, CS; Wu, GJ | 1 |
| Fujita, T; Jin, YH; Nishioka, H; Wakabayashi, K; Yonehara, N | 1 |
| Terman, GW; Thomson, LM; Zeng, J | 1 |
| Gao, H; Lei, H; Liu, M; Ma, Y; Sun, N; Wang, Y; Xiang, Y; Zhu, H | 1 |
| Amin, M; Rawls, SM; Robinson, W; Tallarida, R | 1 |
| Hernández, L; Páez, X; Quiñones, B; Silva, E | 1 |
| Hsin, ST; Lin, FH; Lin, SL; Shen, CH; Tsai, RY; Wang, JJ; Wong, CS | 1 |
| Anderson, DC; Chang, L; Cloak, CC; Donahoe, RM; Ernst, TM; O'Neil, SP | 1 |
| Cherng, CH; Huang, HY; Lee, SO; Tao, PL; Wong, CS; Wu, CT; Yang, CP | 1 |
| Bong, D; Floyd, C; Liao, S; Pino, MJ; Tan, K; Wu, C | 1 |
| Brock, DJ; Corey, M; Durie, P; Hamosh, A; Keston, M; King, TM; Levison, H; McIntosh, I; Rosenstein, BJ; Tsui, LC | 1 |
1 review(s) available for aspartic acid and morphine
| Article | Year |
|---|---|
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid | 1986 |
52 other study(ies) available for aspartic acid and morphine
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Paradoxical brain malate response to morphine.
Topics: Analgesia; Animals; Aspartic Acid; Brain; Brain Chemistry; Carbon Dioxide; Circadian Rhythm; Drug Implants; Glutamates; Malates; Male; Mice; Morphine | 1979 |
Mutual effects of morphine and aspartic acid on brain levels in mice.
Topics: Animals; Aspartic Acid; Brain; Drug Interactions; Mice; Morphine; Time Factors | 1977 |
The antagonizing effect of aspartic acid on the brain levels of monoamines and free amino acids during the development of tolerance to the physical dependence on morphine.
Topics: Amines; Amino Acids; Animals; Aspartic Acid; Brain; Cats; Drug Tolerance; Humans; Morphine; Morphine Dependence; Rats; Serotonin Antagonists | 1977 |
The relationship between morphine, aspartic acid and L-asparaginase in rats.
Topics: Analgesia; Animals; Asparaginase; Aspartic Acid; Brain; Drug Interactions; Kidney; Liver; Morphine; Motor Activity; Rats; Sensory Thresholds | 1979 |
Antagonizing effect of aspartic acid on the development of physical dependence on and tolerance to morphine in the rat.
Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain; Drug Tolerance; Humans; Morphine; Morphine Dependence; Motor Activity; Narcotic Antagonists; Rats | 1977 |
Morphine and pain: effects on aspartate, GABA and glutamate in four discrete areas of mouse brain.
Topics: Aminobutyrates; Animals; Aspartic Acid; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypothalamus; Male; Mice; Morphine; Naloxone; Pain; Reticular Formation; Stress, Physiological | 1976 |
N-methylaspartate-activated calcium channels in rat brain cortex slices. Effect of calcium channel blockers and of inhibitory and depressant substances.
Topics: Animals; Aspartic Acid; Cadmium; Calcium Channel Blockers; Central Nervous System Depressants; Cerebral Cortex; Cobalt; gamma-Aminobutyric Acid; Ion Channels; Morphine; N-Methylaspartate; Nifedipine; Rats; Tetrodotoxin; Time Factors | 1986 |
Morphine (intracerebroventricular) activates spinal systems to inhibit behavior induced by putative pain neurotransmitters.
Topics: Animals; Aspartic Acid; Behavior, Animal; Dose-Response Relationship, Drug; Male; Methysergide; Mice; Morphine; N-Methylaspartate; Naloxone; Neurotransmitter Agents; Nociceptors; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Serotonin; Spinal Cord; Substance P | 1989 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Brain asparaginase, ACE activity and plasma cortisol level in morphine dependent rats: effect of aspartic acid and naloxone.
Topics: Animals; Asparaginase; Aspartic Acid; Brain; Hydrocortisone; Male; Morphine; Naloxone; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1986 |
Opioids and non-opioid enantiomers selectively attenuate N-methyl-D-aspartate neurotoxicity on cortical neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Indicators and Reagents; Methadone; Mice; Morphine; N-Methylaspartate; Naloxone; Narcotics; Neurons; Stereoisomerism | 1988 |
Characterization and possible opioid modulation of N-methyl-D-aspartic acid induced increases in serum luteinizing hormone levels in the developing male rat.
Topics: Aging; Animals; Aspartic Acid; Endorphins; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Morphine; N-Methylaspartate; Naloxone; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains | 1988 |
Aggravation by morphine and D-aspartic acid of pyelonephritis induced by i.v. inoculation of Staphylococcus aureus in rats.
Topics: Animals; Aspartic Acid; Energy Intake; Male; Morphine; Pyelonephritis; Rats; Rats, Inbred Strains; Staphylococcal Infections; Staphylococcus aureus | 1988 |
The inhibition by morphine and D-aspartic acid of antibody production against Salmonella typhimurium antigen in rats: its antagonism by L-aspartic acid.
Topics: Administration, Oral; Animals; Antibody Formation; Antigens, Bacterial; Aspartic Acid; Isomerism; Male; Morphine; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1987 |
The effect of magnesium aspartate, xylazine and morphine on the immobilization-induced increase in the levels of prolactin in turkey plasma.
Topics: Animals; Aspartic Acid; Drug Combinations; Magnesium; Male; Morphine; Poultry Diseases; Prolactin; Restraint, Physical; Stress, Physiological; Thiazines; Turkeys; Xylazine | 1987 |
Morphine blockade of amino acid putative transmitters on cat spinal cord sensory interneurones.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Depression, Chemical; Excitatory Amino Acid Antagonists; Glycine; Homocysteine; In Vitro Techniques; Interneurons; Iontophoresis; Morphine; Spinal Cord; Synaptic Transmission | 1973 |
The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo.
Topics: Acetazolamide; Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Animals; Arteries; Aspartic Acid; Brain; Carbon Dioxide; Citrates; Glucose; Glutarates; Humans; Hydrogen-Ion Concentration; Lactates; Malates; Male; Morphine; Morphine Dependence; Nalorphine; Phosphocreatine; Pyruvates; Rats; Substance Withdrawal Syndrome | 1972 |
The antagonistic effects of aspartic acid on some effects of morphine on rats.
Topics: Analgesics; Animals; Aspartic Acid; Morphine; Motor Activity; Rats | 1974 |
Effects of neurotropic drugs on glucose metabolism in rat brain in vivo.
Topics: Alanine; Amino Acids; Aminobutyrates; Amphetamine; Animals; Aspartic Acid; Brain; Carbon Isotopes; Chlorpromazine; Glucose; Glutamates; Glutamine; Glutarates; Iproniazid; Keto Acids; Male; Morphine; Pentobarbital; Pyruvates; Rats | 1966 |
The effect of morphine, naloxone, D- and L-aspartic acid on the brain and lung ACE in mice.
Topics: Animals; Aspartic Acid; Brain; In Vitro Techniques; Lung; Mice; Mice, Inbred Strains; Morphine; Naloxone; Peptidyl-Dipeptidase A; Stereoisomerism | 1983 |
Neurotransmitter turnover in rat striatum is correlated with morphine self-administration.
Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Humans; Male; Morphine; Morphine Dependence; Neurotransmitter Agents; Norepinephrine; Rats; Self Administration; Serotonin | 1980 |
Vasopressin release by D-aspartic acid, morphine and prolyl-leucyl-glycinamide (PLG) in DI Brattleboro rats.
Topics: Animals; Asparaginase; Aspartic Acid; Brain; Drug Interactions; Heterozygote; Homozygote; Male; Morphine; MSH Release-Inhibiting Hormone; Rats; Rats, Brattleboro; Rats, Inbred Strains; Rats, Mutant Strains; Vasopressins | 1984 |
Profile of amino acid synthesis in rat hippocampus during push-pull perfusion of ethanol or morphine.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Hippocampus; Male; Morphine; Rats; Rats, Inbred Strains | 1984 |
The effects of D- and/or L-aspartic acids on the total weight of body, the weights of certain organs, and their protein, triglyceride and glycogen content.
Topics: Animals; Aspartic Acid; Body Weight; Eating; Glycogen; Metabolism; Morphine; Narcotics; Organ Size; Proteins; Rats; Stereoisomerism; Triglycerides | 1982 |
Antinociceptive effect of D-aspartic acid in mice.
Topics: Analgesics; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Pain Measurement; Time Factors | 1995 |
Opiate withdrawal increases glutamate and aspartate efflux in the locus coeruleus: an in vivo microdialysis study.
Topics: Animals; Aspartic Acid; Drug Implants; Extracellular Space; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Microdialysis; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Naloxone-precipitated morphine withdrawal increases pontine glutamate levels in the rat.
Topics: Animals; Aspartic Acid; Dialysis; Drug Interactions; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Effect of lamotrigine on the electrically-evoked release of endogenous amino acids from slices of dorsal horn of the rat spinal cord.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Glutamic Acid; Lamotrigine; Male; Morphine; Rats; Rats, Wistar; Spinal Cord; Triazines | 1995 |
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine | 1997 |
Effect of precipitated withdrawal on extracellular glutamate and aspartate in the nucleus accumbens of chronically morphine-treated rats: an in vivo microdialysis study.
Topics: Animals; Aspartic Acid; Calcium; Extracellular Space; Glutamic Acid; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1998 |
ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexone.
Topics: Animals; Aspartic Acid; Carboxylic Acids; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ligands; Morphine; Mutagenesis, Site-Directed; Naltrexone; Protein Binding; Rats; Receptors, Opioid, mu | 1999 |
Homology models of mu-opioid receptor with organic and inorganic cations at conserved aspartates in the second and third transmembrane domains.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Aspartic Acid; Benzomorphans; Binding Sites; Cations; Cattle; Computer Simulation; Conserved Sequence; Fentanyl; Humans; Ligands; Metals; Models, Molecular; Molecular Sequence Data; Morphine; Naloxone; Narcotic Antagonists; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Opioid, mu; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2000 |
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia.
Topics: Analysis of Variance; Animals; Arginine; Aspartic Acid; Carrageenan; Citrulline; Dialysis Solutions; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Male; Microdialysis; Morphine; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Thalamic Nuclei | 2000 |
Opioids bind to the amino acids 84 to 118 of UDP-glucuronosyltransferase UGT2B7.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carrier Proteins; Glucuronosyltransferase; Humans; Magnetic Resonance Spectroscopy; Maltose-Binding Proteins; Models, Molecular; Molecular Sequence Data; Morphine; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins | 2003 |
Increasing of intrathecal CSF excitatory amino acids concentration following morphine challenge in morphine-tolerant rats.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Injections, Spinal; Male; Microdialysis; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Time Factors | 2004 |
Neurochemical changes of the extracellular concentrations of glutamate and aspartate in the nucleus accumbens of rats after chronic administration of morphine.
Topics: Animals; Aspartic Acid; Extracellular Fluid; Glutamic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2004 |
Facilitation of morphine withdrawal symptoms and morphine-induced conditioned place preference by a glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate in rats.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Conditioning, Operant; Male; Morphine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2004 |
Dexamethasone modulates the development of morphine tolerance and expression of glutamate transporters in rats.
Topics: Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Aspartic Acid; Dexamethasone; Drug Tolerance; Glucocorticoids; Glutamic Acid; Male; Morphine; Morphine Dependence; Nociceptors; Rats; Rats, Wistar; Spinal Cord | 2005 |
Effect of morphine on the release of excitatory amino acids in the rat hind instep: Pain is modulated by the interaction between the peripheral opioid and glutamate systems.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Capsaicin; Disease Models, Animal; Drug Interactions; Electric Stimulation; Glutamic Acid; Hot Temperature; Male; Morphine; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neural Conduction; Nociceptors; Opioid Peptides; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Opioid; Sensory Receptor Cells; Signal Transduction | 2006 |
Differential effect of glutamate transporter inhibition on EPSCs in the morphine naïve and morphine tolerant neonatal spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Morphine; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Metabolic changes in rat prefrontal cortex and hippocampus induced by chronic morphine treatment studied ex vivo by high resolution 1H NMR spectroscopy.
Topics: Animals; Aspartic Acid; Data Interpretation, Statistical; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Morphine; Narcotics; Prefrontal Cortex; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Taurine | 2007 |
The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Bacterial Agents; Aspartic Acid; beta-Lactams; Body Temperature; Ceftriaxone; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors | 2007 |
[Effect of a simple morphine system injection in some aminoacids in the anterior cingulate cortex during acute pain].
Topics: Acute Disease; Amino Acids; Analgesics, Opioid; Animals; Arginine; Aspartic Acid; Cerebral Cortex; Disinfectants; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Male; Microdialysis; Morphine; Pain; Rats; Rats, Wistar | 2008 |
Co-administration of ultra-low dose naloxone attenuates morphine tolerance in rats via attenuation of NMDA receptor neurotransmission and suppression of neuroinflammation in the spinal cords.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Aspartic Acid; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamic Acid; Injections, Spinal; Male; Morphine; Naloxone; Neuroglia; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 2010 |
Neurometabolite abnormalities in simian immunodeficiency virus-infected macaques with chronic morphine administration.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Creatine; Glutamic Acid; Inositol; Macaca; Magnetic Resonance Spectroscopy; Male; Morphine; Morphine Dependence; Narcotics; Simian Acquired Immunodeficiency Syndrome; Viral Load | 2011 |
Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Behavior, Animal; Disease Models, Animal; Down-Regulation; Drug Synergism; Glutamic Acid; Hyperalgesia; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Threshold; Posterior Horn Cells; Rats; Rats, Wistar; Reaction Time; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Sciatic Nerve; Sciatica; Time Factors; Tumor Necrosis Factor-alpha | 2013 |
Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation.
Topics: Allosteric Regulation; Animals; Aspartic Acid; Cluster Analysis; Conserved Sequence; Crystallization; Humans; Ligands; Mice; Molecular Dynamics Simulation; Morphine; Principal Component Analysis; Protein Conformation; Receptors, Opioid, mu; Signal Transduction; Structural Homology, Protein; Thiophenes; Tyrosine; Urea; Water | 2021 |
Cystic fibrosis patients bearing both the common missense mutation Gly----Asp at codon 551 and the delta F508 mutation are clinically indistinguishable from delta F508 homozygotes, except for decreased risk of meconium ileus.
Topics: Adolescent; Aspartic Acid; Child; Child, Preschool; Codon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Homozygote; Humans; Infant, Newborn; Intestinal Obstruction; Meconium; Membrane Proteins; Mutation; Risk Factors | 1992 |