aspartic acid has been researched along with kainic acid in 552 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 354 (64.13) | 18.7374 |
| 1990's | 135 (24.46) | 18.2507 |
| 2000's | 47 (8.51) | 29.6817 |
| 2010's | 14 (2.54) | 24.3611 |
| 2020's | 2 (0.36) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Davies, J; Polc, P | 1 |
| Berl, S; Duvoisin, R; Nicklàs, WJ; Nunez, R | 1 |
| Fonnum, F; Karlsen, RL; Malthe-Sørenssen, D; Skrede, KK; Walaas, I | 1 |
| Roberts, PJ; Sharif, NA | 1 |
| Lodge, D | 1 |
| Evans, RH; Francis, AA; Watkins, JC | 1 |
| Biscoe, TJ; Davies, J; Dray, A; Evans, RH; Martin, MR; Watkins, JC | 1 |
| Lodge, D; McLennan, H | 1 |
| Davies, J; Evans, RH; Francis, AA; Watkins, JC | 1 |
| Berl, S; Duvoisin, RC; Nicklas, WJ | 1 |
| Adams, JC; Martin, MR | 1 |
| Evans, RH | 2 |
| Davies, J; Watkins, JC | 1 |
| Flatman, JA; Lambert, JD | 1 |
| Engberg, I; Flatman, JA; Lambert, JD | 2 |
| MacDonald, JF; Nistri, A; Padjen, AL | 1 |
| Haefely, W; Polc, P | 1 |
| MacDonald, JF; Nistri, A | 1 |
| Hall, JG; McLennan, H | 1 |
| Cicero, TJ; Olney, JW; Price, MT | 1 |
| Dawson, R; Glenton, P; Meldrum, MJ | 1 |
| Gallo, V; Giovannini, C; Levi, G | 3 |
| Bachurin, SO; Drany, OA; Petrova, LN; Solyakov, LS | 1 |
| Botscheller, M; Palmer, AM; Reiter, CT | 1 |
| Chuang, DM; Gao, XM; Paul, SM | 1 |
| Fernández-Sánchez, MT; Kispert, J; Novelli, A; Torreblanca, A; Zitko, V | 1 |
| Chizhmakov, IV; Jackson, H; Kiskin, NI; Krishtal, OA; Mueller, AL | 1 |
| Berg, M; Bruhn, T; Cobo, M; Diemer, NH | 1 |
| Cazalets, JR; Clarac, F; Sqalli-Houssaini, Y | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Fain, GL; Yazejian, B | 1 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Bockaert, J; Heinemann, SF; Pin, JP; Prezeau, L; Waeber, C | 1 |
| Anderson, KJ; Mitchell, JJ | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Bowe, MA; Bray, SD; Bustos, GA; Martin, D; Nadler, JV | 1 |
| Marini, A; Novelli, A | 1 |
| Attwell, D; Barbour, B; Brew, H | 1 |
| Carter, AJ; Müller, RE | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Onodera, K; Takeuchi, A | 1 |
| Hsu, CH; Matthews, JC; Morris, KR | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Oja, SS; Saransaari, P | 3 |
| Rios, C; Santamaria, A | 1 |
| Albuquerque, EX; Alkondon, M; Aronstam, RS; Costa, AC; Radhakrishnan, V | 1 |
| Ohmori, H; Yamaguchi, K | 1 |
| Cull-Candy, SG; Traynelis, SF | 1 |
| Brackley, P; Goodnow, R; Nakanishi, K; Sudan, HL; Usherwood, PN | 1 |
| Dichter, M; Morad, M; Tang, CM | 1 |
| Larson, AA; Skilling, SR; Smullin, DH | 1 |
| Colquhoun, D; Cull-Candy, SG; Howe, JR | 1 |
| Corden, M; Curry, K; McLennan, H | 1 |
| Brehm, L; Jørgensen, FS; Krogsgaard-Larsen, P; Madsen, U; Schaumburg, K | 1 |
| Ziskind-Conhaim, L | 1 |
| Church, J; Lodge, D | 1 |
| Harrison, PH | 1 |
| Glaum, SR; Miller, RJ; Scholz, WK | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Butterworth, RF; Cotman, CW; Giguere, JF; Peterson, C | 1 |
| Baimbridge, KG; Choi, DW; Koh, J; Weiss, JH | 1 |
| Hestrin, S; Nicoll, RA; Sah, P | 1 |
| Nicholson, C; Rice, ME | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Collingridge, GL; Davies, SN | 1 |
| Kimura, F; Nishigori, A; Tsumoto, T | 1 |
| Benson, CG; Chase, MC; Potashner, SJ | 1 |
| Ikeda, H; Kay, CD; Robbins, J | 2 |
| Colpaert, FC; Koek, W | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Brooks, DN; Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J | 1 |
| Dutton, GR; Philibert, RA; Rogers, KL | 1 |
| Choi, DW; Hartley, DM; Koh, J; Weiss, JH | 1 |
| Osborne, NN | 1 |
| Keith, RA; Klika, AB; Mangano, TJ; Patel, J; Salama, AI; Zinkand, WC | 1 |
| De Montigny, C; Debonnel, G; Junien, JL; Monnet, FP | 1 |
| Berrino, L; Loffreda, A; Maione, S; Marmo, E; Matera, MG; Vitagliano, S | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Mayer, ML; Patneau, DK | 1 |
| Johnson, BG; McQuaid, LA; Schoepp, DD; Smith, EC | 1 |
| Masetto, S; Prigioni, I; Russo, G; Valli, P | 1 |
| Akaike, N; Fukuda, A; Nakagawa, T; Shirasaki, T; Wakamori, M | 1 |
| Colpaert, FC; Koek, W; Woods, JH | 1 |
| Herreras, O; Martín del Río, R; Menéndez, N; Sánchez Herranz, A; Solís, JM | 1 |
| Godfraind, JM | 1 |
| Erdö, SL; Michler, A | 1 |
| de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Schwartz, EA; Tachibana, M | 1 |
| Kulkarni, SK; Mehta, AK; Ticku, MK | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 1 |
| Michl, J; Ujec, E; Vlachová, V; Vyklický, L; Vyskocil, F | 1 |
| Aanonsen, LM; Wilcox, GL | 3 |
| MacDonald, JF; Miljkovic, Z | 1 |
| Fischbach, GD; O'Brien, RJ | 3 |
| MacDonald, JF; Miljkovic, Z; Pennefather, P | 1 |
| Bean, BP; Huettner, JE | 1 |
| Forsythe, ID; Nelson, PG | 1 |
| Coull, BM; Woodward, WR | 2 |
| Cull-Candy, SG; Howe, JR; Ogden, DC | 1 |
| Edwards, C; Krusek, J; Vyklicky, L | 1 |
| Bennett, MV; Kushner, L; Lerma, J; Zukin, RS | 1 |
| Lovinger, DM; Weight, FF; White, G | 1 |
| Gruol, DL; Joels, M; Yool, AJ | 1 |
| Cull-Candy, SG; Gallo, V; Usowicz, MM | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Heinemann, S; Hollmann, M; O'Shea-Greenfield, A; Rogers, SW | 1 |
| Chapman, AG; Dürmuller, N; Lees, GJ; Meldrum, BS | 1 |
| Belaidi, M; Kamenka, JM; Lerner-Natoli, M; N'Gouemo, P; Rondouin, G | 1 |
| Cahill, GM; Menaker, M | 1 |
| Alho, H; Barbaccia, ML; Costa, E; Szekely, AM | 1 |
| Backus, KH; Kettenmann, H; Schachner, M | 1 |
| Bourguignon, JP; Franchimont, P; Gérard, A | 1 |
| Salt, TE | 1 |
| Kegerise, C; Noszek, JC; Siman, R | 1 |
| Bourguignon, JP; Franchimont, P; Gerard, A; Mathieu, J; Simons, J | 1 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Garthwaite, G; Garthwaite, J | 5 |
| Dingledine, R; Kleckner, NW | 1 |
| Cotman, CW; Monaghan, DT; Palmer, E | 2 |
| Curran, T; Hempstead, J; Macgregor-Leon, PF; Mitchelmore, C; Morgan, JI; Sonnenberg, JL | 1 |
| Janssen, PA; Leysen, JE; Pauwels, PJ; Van Assouw, HP | 1 |
| Barish, ME; Sands, SB | 1 |
| de Montigny, C; Debonnel, G; Weiss, M | 1 |
| MacDonald, JF; Mody, I; Salter, MW | 1 |
| Caspary, DM; Faingold, CL | 1 |
| Bauce, L; Kemp, DE; Weiss, S | 1 |
| Ito, I; Sugiyama, H; Watanabe, M | 1 |
| McCaslin, PP; Morgan, WW | 2 |
| Leysen, JE; Pauwels, PJ; van Assouw, HP | 1 |
| Gallo, V; Giovannini, C; Levi, G; Suergiu, R | 2 |
| Fonnum, F; Syvertsen, C | 1 |
| Araneda, R; Bustos, G | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| O'Dell, TJ | 1 |
| Harris, KM; Miller, RJ | 2 |
| Westerberg, E; Wieloch, TW | 1 |
| Miller, RJ; Murphy, SN | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Oertel, D; Wickesberg, RE | 1 |
| Abbott, NJ; Hassan, S; Lieberman, EM | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| Beart, PM; Cincotta, M; Summers, RJ | 1 |
| Belhage, B; Bouchelouche, P; Drejer, J; Frandsen, A; Schousboe, A | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Beani, L; Bianchi, C; Jope, RS; Simonato, M | 1 |
| Herranz, AS; Herreras, O; Martín del Río, R; Menéndez, N; Solis, JM | 1 |
| Miyachi, E; Murakami, M | 1 |
| Dubinsky, JM; Rothman, SM; Yamada, KA | 1 |
| Anis, NA; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Konno, K; Miledi, R; Ragsdale, D | 1 |
| Akerman, KE; Heinonen, E; Panula, P | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Bieger, D; Hashim, MA | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Keith, RA; Mangano, TJ; Salama, AI | 1 |
| Drejer, J; Frandsen, A; Schousboe, A | 1 |
| Hornfeldt, CS; Larson, AA | 1 |
| Brunori, A; Mayer, ML; Sugiyama, K | 1 |
| Mayer, ML; Westbrook, GL | 3 |
| Abarca, J; Arqueros, L; Bustos, G | 1 |
| Turski, WA | 1 |
| Friedemann, M; Gerhardt, GA | 1 |
| Barrington, M; Ehrlich, D; Sattayasai, J; Zappia, J | 1 |
| Acuff, CG; Clower, BR; Rockhold, RW | 1 |
| Talman, WT | 1 |
| Shreve, PE; Uretsky, NJ | 3 |
| Davies, LP; Dodd, PR; Dyer, JA; Johnston, GA; Nielsen, B; Watson, WE; Wong, LS | 1 |
| Drejer, J; Schousboe, A | 1 |
| Bustos, G; Rudolph, MI | 1 |
| Drejer, J; Honoré, T | 1 |
| Aizenman, E; Karschin, A; Lipton, SA | 1 |
| Schmidt, CJ; Taylor, VL | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Meldrum, BS; Millan, MH; Patel, S | 1 |
| Noszek, JC; Siman, R | 1 |
| McBean, GJ; Roberts, PJ | 1 |
| Harrison, NL; Simmonds, MA | 1 |
| Bloomfield, SA; Dowling, JE | 1 |
| Cornford, EM | 1 |
| Christensen, BN; Hals, G; Shingai, R | 1 |
| Collins, JF; Meldrum, BS; Turski, L | 1 |
| Harris, RA | 1 |
| Labruyere, J; Olney, JW; Price, MT; Samson, L | 1 |
| Giles, D; Usherwood, PN | 1 |
| Cohen, A; Erez, U; Frenk, H; Goldberg, O; Teichberg, VI | 1 |
| Garthwaite, J | 2 |
| Cotman, CW; Monaghan, DT; Yao, D | 1 |
| Homma, S | 1 |
| Besharse, JC; Greenberger, LM | 1 |
| Gray, PN; May, PC | 1 |
| Higashima, M; Sawada, S; Yamamoto, C | 1 |
| Barnabei, O; Bissoli, R; Contestabile, A; Migani, P; Poli, A; Rondelli, C; Rossi, L; Virgili, M | 1 |
| Goldberg, O; Teichberg, VI | 2 |
| Davies, J; Quinlan, JE | 1 |
| Baba, A; Iwata, H; Morimoto, H | 1 |
| Hagberg, H; Hamberger, A; Lehmann, A; Nyström, B; Sandberg, M | 1 |
| Lodge, D; Martin, D | 2 |
| Hamberger, A; Jacobson, I | 1 |
| Brodin, L; Grillner, S | 1 |
| Cotman, CW; Ganong, AH | 1 |
| Martin, MR | 2 |
| Campochiaro, P; Coyle, JT; Ferkany, JW | 2 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| López-Colomé, AM; Somohano, F | 3 |
| Bockaert, J; Pin, JP; Recasens, M | 1 |
| Addae, JI; Stone, TW | 1 |
| Collins, JF; Stone, TW | 1 |
| Ariel, M; Dowling, JE; Mangel, SC | 1 |
| Drejer, J; Honoré, T; Meier, E; Schousboe, A | 1 |
| Cha, JH; Dowling, JE; O'Brien, DR | 1 |
| Gale, K; Piredda, S | 1 |
| Bobbin, RP; Jenison, GL; Winbery, S | 1 |
| Johnson, KM; Snell, LD | 1 |
| Choi, DW; Koh, JY; Peters, S | 2 |
| Connick, JH; Stone, TW | 2 |
| Cotman, CW; Geddes, JW | 1 |
| Sloviter, RS | 1 |
| Moran, J; Pasantes-Morales, H; Redburn, DA | 1 |
| Butcher, SP; Hamberger, A | 1 |
| Butcher, SP; Hagberg, H; Hamberger, A; Sandberg, M | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Johnson, KM; Jones, SM; Snell, LD | 1 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Cotman, CW; Monaghan, DT; Westerberg, E; Wieloch, T | 1 |
| Choi, DW; Koh, J; Peters, S | 1 |
| Anderton, PJ; Normann, RA; Perlman, I | 1 |
| Falk, G; Shiells, RA | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 1 |
| Compton, RP; Hood, WF; Michel, J; Monahan, JB; Olney, JW; Price, MT; Pullan, LM | 1 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Morgan, IG | 1 |
| Butcher, SP; Hamberger, A; Lazarewicz, JW | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Greenamyre, JT; Olson, JM; Penney, JB; Young, AB | 1 |
| Benavides, J; Carter, C; Fage, D; Scatton, B | 1 |
| Alho, H; Costa, E; Eva, C; Fadda, E; Nicoletti, F; Wroblewski, JT | 1 |
| Frierdich, G; Labruyere, J; Mahan, K; Olney, JW; Price, MT; Ryerson, R; Salles, KS; Samson, L | 1 |
| Bradford, HF; Crowder, JM; Young, AM | 1 |
| Murphie, HM; Nicholls, DG; Pocock, JM | 1 |
| Dryer, SE | 1 |
| Walker, JB; Woznicki, DT | 1 |
| Nishizaki, T; Okada, Y; Yamauchi, R | 1 |
| Beart, PM; Headley, PM; Nicolopoulos, LS; West, DC | 1 |
| Bockaert, J; Pin, JP; Van-Vliet, BJ | 1 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 1 |
| Burke, SP; Nadler, JV | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Foster, AC; Gill, R; Woodruff, GN | 1 |
| Brodin, L; Grillner, S; Ohta, Y; Tossman, U; Ungerstedt, U | 1 |
| Jankásková, B; Lisý, V; Murphy, S; Pearce, B; Stastný, F | 1 |
| Davidoff, RA; Hackman, JC; Wohlberg, CJ | 1 |
| Davidson, N; Fong, TM; Lester, HA | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Massey, SC; Miller, RF | 1 |
| Farley, JM; Huang, HM; Jin, C; Rockhold, RW | 1 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 1 |
| Jones, AW; Meldrum, BS; Turski, L; Watkins, JC | 1 |
| D'Ascanio, P; Lucacchini, A; Martini, C; Pompeiano, O | 1 |
| Anand, H; Badman, G; Collins, JF; Dixon, AJ; Roberts, PJ | 1 |
| Blake, J; Church, J; Davies, SN; Jacobson, AE; Lessor, RA; Lodge, D; Rice, KC | 1 |
| Nauta, HJ; Pisharodi, M | 1 |
| Meldrum, B | 1 |
| Kasarskis, EJ; Slevin, JT; Vanaman, TC; Zurini, M | 1 |
| Herrling, PL; Klockgether, T; Sontag, KH; Turski, L; Watkins, JC | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Wohlberg, CJ | 1 |
| Meldrum, BS; Turski, L; Turski, WA; Watkins, JC | 1 |
| Evans, RH; Evans, SJ; Pook, PC; Sunter, DC | 1 |
| Choi, DW; Peters, S; Viseskul, V | 1 |
| Halsey, MJ; Meldrum, BS; Wardley-Smith, B | 1 |
| Card, JP; Siman, R | 1 |
| Besharse, JC; Spratt, G | 1 |
| Akaike, N; Carpenter, DO; Hori, N | 1 |
| De Sarro, GB; Meldrum, BS; Patel, S | 1 |
| McLarnon, JG; Quastel, DM | 1 |
| Ishimoto, I; Millar, TJ; Morgan, IG; Winder, C | 1 |
| Ebina, Y; Shingai, R | 1 |
| Bunch, ST; Dunnett, SB; Jones, GH; Whishaw, IQ | 1 |
| Foster, AC; Gill, R; Kemp, JA; Woodruff, GN | 1 |
| Carpenter, DO; Galeno, T; Hori, N | 1 |
| Ehrlich, D; Sattayasai, J | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Church, J; Davies, SN; Lodge, D | 1 |
| Frierdich, G; Labruyere, J; Olney, J; Price, M; Salles, KS | 1 |
| Garthwaite, G; Garthwaite, J; Yamini, B | 1 |
| Miller, RJ; Murphy, SN; Thayer, SA | 1 |
| Bandler, R; Carrive, P | 1 |
| Geula, C; Jarvie, PA; Logan, TC; Slevin, JT | 1 |
| Blake, JC; Church, J; Davies, SN; Lodge, D; Martin, D | 1 |
| Agrawal, SG; Evans, RH | 1 |
| Carpenter, M; Fuller, TA; Labruyere, J; Mahan, K; Olney, JW; Price, MT; Samson, L | 1 |
| Garthwaite, G; Garthwaite, J; Hajós, F | 3 |
| Connick, JH; Heywood, GC; Smith, DA; Stone, TW | 1 |
| Hagberg, H; Hamberger, A; Jacobson, I; Lazarewicz, JW; Lehmann, A | 1 |
| Kurcewicz, I; Louvel, J; Pumain, R | 1 |
| Heinemann, U | 1 |
| Ben-Ari, Y; Cherubini, E; Gho, M; Rovira, C | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Klockgether, T; Meldrum, BS; Schwarz, M; Sontag, KH; Turski, L | 1 |
| Butcher, SP; Collins, JF; Roberts, PJ | 1 |
| Kato, S; Negishi, K; Teranishi, T | 1 |
| Chapman, AG; Hart, GP; Meldrum, BS; Turski, L; Watkins, JC | 1 |
| Johnston, GA; Lodge, D | 1 |
| Pearson, RC; Sofroniew, MV | 1 |
| Biscoe, TJ; Burton, NR; Duchen, MR | 1 |
| Stone, TW | 1 |
| Arbuthnott, GW; Garcia-Munoz, M; Hamilton, MH | 1 |
| Rothman, SM | 1 |
| Anand, H; Collins, JF; Roberts, PJ | 1 |
| Berry, SC; Dawkins, SL; Lodge, D | 1 |
| George, SR; Meissl, H | 1 |
| Bledsoe, SC; Bobbin, RP; Chihal, DM; Morgan, DN | 1 |
| Evans, RH; Watkins, JC | 1 |
| Watkins, JC | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 2 |
| Foster, GA; Roberts, PJ | 1 |
| McLennan, H | 3 |
| Goldberg, O; Luini, A; Teichberg, VI | 3 |
| Hambley, JW; Rogers, LJ | 1 |
| Liu, J; McLennan, H | 1 |
| Bauer, B | 1 |
| Collingridge, GL; McLennan, H | 1 |
| Rowe, JS; Ruddock, KH | 1 |
| Barnabei, O; Bissoli, R; Contestabile, A; Cristini, G; Migani, P; Poli, A | 1 |
| Evans, RH; Smith, DA | 1 |
| Bledsoe, SC; Bobbin, RP | 1 |
| Donaldson, PL; Duce, IR; Usherwood, PN | 1 |
| Berdichevsky, E; Orrego, F; Riveros, N; Sánchez-Armáss, S | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 1 |
| Miller, RF; Slaughter, MM | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Donzanti, BA; Uretsky, NJ | 3 |
| Kamp, CW; Morgan, WW | 1 |
| Collingridge, GL; Kehl, SJ; Loo, R; McLennan, H | 1 |
| Morán, J; Pasantes-Morales, H | 1 |
| Neal, M | 1 |
| Ariel, M; Dowling, JE; Lasater, EM; Mangel, SC | 1 |
| Ishida, AT | 1 |
| Kerkut, GA; Mat Jais, AM; Sharma, RP; Walker, RJ | 1 |
| Chapman, AG; Meldrum, BS; Premachandra, M; Westerberg, E | 1 |
| Fagg, GE; Foster, AC | 1 |
| Kamada, Y; Matsuda, M; Miyazaki, H; Mizuno, A; Tsuneoka, H | 1 |
| Barnabei, O; Contestabile, A; Migani, P; Poli, A; Rondelli, C; Rossi, L; Virgili, M | 1 |
| Anis, NA; Berry, SC; Lodge, D | 1 |
| Connor, JD; Constanti, A; Galvan, M; Nistri, A | 1 |
| Falk, G; Naghshineh, S; Shiells, RA | 1 |
| Coyle, JT; Ferkany, JW; Zaczek, R | 1 |
| Hill, RG; Salt, TE | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Kato, M; Maruhashi, J; Oomura, Y; Shimizu, N | 1 |
| Perkins, MN; Stone, TW | 1 |
| Abe, T; Kawai, N; Miwa, A | 1 |
| Dale, N; Roberts, A | 1 |
| Yazulla, S | 1 |
| Ayoub, GS; Lam, DM | 1 |
| Jones, AW; Smith, DA; Watkins, JC | 1 |
| Coyle, JT; Koller, KJ; Zaczek, R | 1 |
| Jhamandas, K; Notman, H; Whitney, R | 1 |
| Arnauld, E; Layton, BS; Padjen, AL; Renaud, LP | 1 |
| Coyle, JT; Ferkany, JW | 1 |
| Ishida, AT; Kaneko, A; Tachibana, M | 1 |
| Erecińska, M; Pastuszko, A; Wilson, DF | 1 |
| Collins, JF; Perkins, MN; Stone, TW | 1 |
| Dawbarn, D; Pycock, CJ | 1 |
| Gerard, D; Potashner, SJ | 1 |
| Kerwin, RW; Luscombe, GP; Pycock, CJ; Sverakova, K | 1 |
| Davies, J; Evans, RH; Francis, AA; Jones, AW; Watkins, JC | 1 |
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| Alfonso, M; Arias, B; Arufe, MC; Durán, R | 1 |
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| Ebinger, G; Michotte, Y; Sarre, S; Smolders, I; Vanhaesendonck, C | 1 |
| Kaneko, A; Sasaki, T | 1 |
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| Massieu, L; Tapia, R; Velasco, I | 1 |
| Lewin, L; Mattsson, MO; Sellström, A | 1 |
| Allan, RD; Balcar, VJ; Bested, A; Blume, GL; Bohart, L; Cooper, B; Dias, LS; Killinger, S | 1 |
| Ebisu, T; Graham, SH; Mancuso, A; Maudsley, AA; Rooney, WD; Weiner, MW | 1 |
| Bouazzaoui, M; Gombos, G; Kannengieser, C; Procksch, O | 1 |
| Comair, YG; Hong, SC; Lüders, HO; Najm, IM; Ng, TC; Wang, Y | 1 |
| Mancuso, A; Maudsley, AA; Naruse, S; Tokumitsu, T; Weiner, MW; Weinstein, PR | 1 |
| Deitmer, JW; Schneider, HP | 1 |
| Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Carvalho, AP; Duarte, CB; Santos, PF | 1 |
| Wu, SM; Yang, JH | 1 |
| Massieu, L; Tapia, R | 1 |
| Bigelow, LB; Herman, MM; Hyde, TM; Kleinman, JE; Noga, JT; Spurney, CF; Weinberger, DR | 1 |
| Gaal, L; Marc, R; Picaud, SA; Roska, B; Werblin, FS; Wu, SM | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO | 1 |
| de Mello, FG; de Mello, MC; Kubrusly, RC | 1 |
| Crosson, CE; Ganel, R | 1 |
| Comair, YG; Lüders, HO; Najm, IM; Ng, TC; Shedid, D; Wang, Y | 1 |
| Grunewald, M; Kanner, BI; Kavanaugh, MP; Zarbiv, R | 1 |
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| Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Bianchi, L; Bolam, JP; Colivicchi, MA; Della Corte, L | 1 |
| Feustel, PJ; Keller, RW; Kimelberg, HK; Seki, Y; Tranmer, BI | 1 |
| Kanner, BI; Zhang, Y | 1 |
| D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G | 1 |
| Baudry, M; Broutman, G; Crispino, M; Hoe, W; Rothstein, JD; Simantov, R; Tocco, G | 1 |
| Irić-Cupić, V; Janković, SM; Matović, M; Milovanović, D | 1 |
| Bar-Peled, O; Knudson, M; Korsmeyer, SJ; Rothstein, JD | 1 |
| Clarke, EE; Gervais, FG; Huang, J; LeBlanc, A; Nicholson, DW; Rigby, M; Robertson, GS; Roy, S; Ruffolo, SC; Shearman, MS; Smith, D; Thornberry, NA; Vaillancourt, JP; Van Der Ploeg, LH; Xanthoudakis, S; Xu, D; Zamboni, RJ; Zheng, H; Zhu, Y | 1 |
| Bridges, RJ; Chamberlin, AR; Koch, HP | 1 |
| Baca, SM; Hyde, TM; Jaskiw, GE; Kleinman, JE; Murray, AM; Spurney, CF | 1 |
| Anderson, KJ; Burchfield, DJ; Mason, KL; McGraw, TS; Sapper, MS; Theophilopoulos, DT | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Araque, A; Doyle, RT; Haydon, PG; Li, N | 1 |
| Trussell, LO; Turecek, R | 1 |
| Isaac, JT; Kidd, FL | 2 |
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| Bézine, MF; Gaillet, S; Malaval, F; Plachez, C; Récasens, M | 1 |
| Dawson, LA; Djali, S; Gonzales, C; Vinegra, MA; Zaleska, MM | 1 |
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| Bourne, JA; Fosbraey, P; Halliday, J | 1 |
| Cheng, JK; Lin, CR; Marsala, M; Tsai, PS; Wen, GH; Yang, LC | 1 |
| Kimmich, GA; Manglapus, M; Randles, J; Roussie, J | 1 |
| Calaza, KC; de Mello, FG; Gardino, PF | 1 |
| Anderson, CM; Bridges, RJ; Chamberlin, AR; Shimamoto, K; Swanson, RA; Yasuda-Kamatani, Y | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P | 1 |
| Chen, Y; Swanson, RA | 1 |
| Bianchi, L; Bolam, JP; Della Corte, L; Galeffi, F | 1 |
| Calaza, Kda C; de Mello, FG; de Mello, MC; Gardino, PF | 1 |
| Fei, J; Guo, LH; Hu, JH; Jiang, J; Ma, YH; Yang, N; Zhang, JF | 1 |
| Feustel, PJ; Jin, Y; Kimelberg, HK | 1 |
| Alonso, TJ; Castro Fuentes, R; García Dopico, J; González Hernández, T; Perdomo Díaz, J; Rodríguez Díaz, M | 1 |
| Grebenyuk, S; Kirichok, Y; Krishtal, O; Lozovaya, N; Melnik, S; Tsintsadze, T | 1 |
| Cohen, ED; Dowling, JE; Wong, KY | 1 |
| Guy, Y; Jilderos, B; Sandberg, M; Stridh, MH; Tranberg, M; Weber, SG; Wigström, H | 1 |
| Chen, L; Liao, WP | 1 |
| Bringmann, A; Klaus, C; Reichenbach, A; Rillich, K; Syková, E; Uckermann, O; Ulbricht, E; Vargová, L; Weick, M; Wiedemann, P | 1 |
| Dohovics, R; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Dowling, JE; Wong, KY | 1 |
| Kettenmann, H; Kresse, W; Rose, C | 1 |
| Foster, AC; Naeve, GS; Poulsen, DJ; Selkirk, JV; Stiefel, TH; Stone, IM | 1 |
| Bannister, NJ; Benke, TA; Crabtree, JW; Gürdal, E; Isaac, JT; Mellor, J; Scott, H | 1 |
| Cechova, S; Zuo, Z | 1 |
| Terman, GW; Thomson, LM; Zeng, J | 1 |
| Ballini, C; Bianchi, L; Colivicchi, MA; Della Corte, L; Fattori, M; Giovannini, MG; Healy, J; Tipton, KF; Venturi, C | 1 |
| Aniksztejn, L; Becq, H; Ben-Ari, Y; Milh, M; Villeneuve, N | 1 |
| Kettenmann, H; Kirischuk, S; Verkhratsky, A | 1 |
| Bonanno, G; Fedele, E; Milanese, M; Raiteri, L; Raiteri, M; Zappettini, S | 1 |
| Kanner, BI; Qu, S | 1 |
| Campbell, SL; Hablitz, JJ | 1 |
| Hosseinzadeh, H; Rahimi, A; Sadeghnia, HR | 1 |
| Bernardinelli, Y; Chatton, JY | 1 |
| Hille, B; Kim, MH; Koh, DS; Moriyama, Y; Muroyama, A; Uehara, S | 1 |
| DeSilva, TM; Goldhoff, PE; Kabakov, AY; Rosenberg, PA; Volpe, JJ | 1 |
| Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM | 1 |
| Chandran, G; Sirajudeen, KN; Swamy, M | 1 |
| Cervetto, C; Marcoli, M; Maura, G | 1 |
| Kardos, J; Lasztóczi, B; Nyitrai, G | 1 |
| Bertsche, A; Bruehl, C; Draguhn, A; Pietz, J | 1 |
| Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M | 1 |
| Barton, SJ; Bunner, KD; Dorner, JL; Gaither, TW; Klein, EL; Miller, BR; Rebec, GV | 1 |
| Jiang, E; Weng, HR; Yan, X | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Alva, N; Carbonell, T; Costa, DC; Gamez, A; Rama, R; Trigueros, L | 1 |
| Fischer, KD; Houston, AC; Rebec, GV | 1 |
| Kavanaugh, AS; Langford, MP; Liang, C; Redens, TB; Texada, DE | 1 |
| de Lanerolle, NC; Hitchens, TK; Pan, JW; Pearce, PS; Rapuano, A; Wu, Y | 1 |
| Berretta, N; Cecconi, F; Cervelli, M; Cervetto, C; D'Amelio, M; Marcoli, M; Mariottini, P; Maura, G; Mercuri, N; Passalacqua, M; Ragazzoni, M; Venturini, A; Vergani, L; Voci, A | 1 |
| de Lanerolle, N; Kelly, KM; Pan, JW; Pearce, PS; Rapuano, A; Wu, Y | 1 |
| Bajrektarevic, D; Nistri, A | 1 |
| Bendre, AD; Bhosale, S; Burada, AP; Joshi, M; Kumar, J; Kumari, J; Peters, PJ; Ravelli, RBG; Tria, G; Vinnakota, R | 1 |
| Amatuni, A; Li, J; Renata, H | 1 |
7 review(s) available for aspartic acid and kainic acid
| Article | Year |
|---|---|
Quinoxalinediones as excitatory amino acid antagonists in the vertebrate central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Binding, Competitive; Central Nervous System; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Spinal Cord; Structure-Activity Relationship; Vertebrates | 1990 |
In vivo regulation of extracellular taurine and other neuroactive amino acids in the rabbit hippocampus.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Ethanolamines; Extracellular Space; Hippocampus; Iodoacetates; Iodoacetic Acid; Ischemia; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Potassium; Rabbits; Taurine | 1985 |
The physiology of excitatory amino acids in the vertebrate central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Central Nervous System; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Vertebrates | 1987 |
Pharmacology of excitatory amino acid transmitters.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate | 1981 |
The stimulation of ion fluxes in brain slices by glutamate and other excitatory amino acids.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Brain; Calcium; Cations; Cell Membrane Permeability; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; N-Methylaspartate; Potassium; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase | 1981 |
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Brain; Brain Chemistry; Cats; Electrophysiology; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Ligands; Mice; Neurotransmitter Agents; Oxidation-Reduction; Radioligand Assay; Rats; Receptors, Neurotransmitter; Synaptic Transmission | 1984 |
Recent advances in the chemoenzymatic synthesis of bioactive natural products.
Topics: Aspartic Acid; Biocatalysis; Biological Products; Enzymes; Isoquinolines; Kainic Acid; Molecular Conformation; Podophyllotoxin; Quinolines; Quinolones; Stereoisomerism | 2020 |
545 other study(ies) available for aspartic acid and kainic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effects of L-nuciferine on kainate, N-methyl-D-aspartate and acetylcholine excitation of cat spinal neurons.
Topics: Acetylcholine; Animals; Aporphines; Aspartic Acid; Cats; Drug Interactions; In Vitro Techniques; Kainic Acid; Neurons; Pyrrolidines; Spinal Cord | 1979 |
Neuronal-glial contributions to transmitter amino acid metabolism: studies with kainic acid-induced lesions of rat striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Kainic Acid; Neuroglia; Neurons; Neurotransmitter Agents; Pyrrolidines; Rats | 1979 |
Localization of neurotransmitters, particularly glutamate, in hippocampus, septum, nucleus accumbens and superior colliculus.
Topics: Animals; Aspartic Acid; Brain; Glutamates; Hippocampus; In Vitro Techniques; Kainic Acid; Neurotransmitter Agents; Nucleus Accumbens; Rats; Superior Colliculi | 1979 |
Effects of l-glutamate and related amino acids upon the release of [3H]dopamine from rat striatal slices.
Topics: Amino Acids; Animals; Aspartic Acid; Dopamine; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Glutamates; Homocysteine; In Vitro Techniques; Isomerism; Kainic Acid; Osmolar Concentration; Rats; Receptors, Dopamine; Structure-Activity Relationship; Visual Cortex | 1978 |
L-histidine: effects on sensitivity of cat spinal neurones to amino acids.
Topics: Amino Acids; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Cats; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Histidine; Kainic Acid; Muscimol; Spinal Cord | 1979 |
Mg2+-like selective antagonism of excitatory amino acid-induced responses by alpha, epsilon-diaminopimelic acid, D-alpha-aminoadipate and HA-966 in isolated spinal cord of frog and immature rat.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Anura; Aspartic Acid; Diaminopimelic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Kainic Acid; Magnesium; Motor Neurons; Pimelic Acids; Pyrrolidinones; Rats; Spinal Cord; Synaptic Transmission | 1978 |
D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo.
Topics: 2-Aminoadipic Acid; Acetylcholine; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Cats; Diaminopimelic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Interneurons; Kainic Acid; Mice; Mice, Inbred C3H; Motor Neurons; Pimelic Acids; Pyrrolidinones; Spinal Cord; Synapses; Synaptic Transmission | 1978 |
The antagonism of amino acid-induced excitation of spinal neurones in the cat.
Topics: 2-Aminoadipic Acid; Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cats; Cysteic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Interneurons; Kainic Acid; Neurons; Receptors, Neurotransmitter; Spinal Cord | 1979 |
Excitatory amino acid receptors and synaptic excitation in the mammalian central nervous system.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Spinal Nerve Roots | 1979 |
Amino acids in rat neostriatum: alteration by kainic acid lesion.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Behavior, Animal; Caudate Nucleus; Choline; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Kainic Acid; Putamen; Pyrrolidines; Rats; Synaptosomes | 1979 |
Effects of DL-alpha-aminoadipate on synaptically and chemically evoked excitation of anteroventral cochlear nucleus neurons of the cat.
Topics: 2-Aminoadipic Acid; Acetylcholine; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Cats; Cochlear Nerve; Electric Conductivity; Evoked Potentials; Female; Glutamates; Kainic Acid; Male; Neurons; Synapses | 1979 |
Further evidence suggesting the absence of acidic amino acid receptors on primary afferent terminals in the frog [proceedings].
Topics: Amino Acids; Animals; Anura; Aspartic Acid; Evoked Potentials; Glutamates; In Vitro Techniques; Kainic Acid; Motor Neurons; Nerve Endings; Neurons, Afferent; Receptors, Drug; Spinal Nerve Roots | 1979 |
Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord.
Topics: 2-Aminoadipic Acid; Acetylcholine; Action Potentials; Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Aspartic Acid; Cats; Glutamates; Homocysteine; Interneurons; Kainic Acid; Neurons; Organophosphorus Compounds; Spinal Cord; Synapses | 1979 |
Sustained extracellular potentials in the cat spinal cord during the microiontophoretic application of excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Cats; Evoked Potentials; Female; Glutamates; Homocysteine; Iontophoresis; Kainic Acid; Male; Microinjections; Micromanipulation; Motor Neurons; Neuroglia; Spinal Cord | 1979 |
A comparison of extracellular and intracellular recording during extracellular microiontophoresis.
Topics: Amino Acids; Animals; Aspartic Acid; Cats; Dopamine; Electrophysiology; Evoked Potentials; Glutamates; Homocysteine; Iontophoresis; Kainic Acid; Microelectrodes; Microinjections; Norepinephrine; Spinal Cord | 1979 |
Neuronal depressant effects of diethylester derivatives of excitatory amino acids.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cats; Evoked Potentials; Glutamates; Kainic Acid; Neurons; Spinal Cord | 1977 |
Effects of intravenous kainic acid, N-methyl-D-aspartate, and (--)-nuciferine on the cat spinal cord.
Topics: Animals; Aporphines; Aspartic Acid; Cats; Evoked Potentials; Injections, Intravenous; Kainic Acid; Pyrrolidines; Reflex; Spinal Cord | 1977 |
A comparison of the action of glutamate, ibotenate and other related amino acids on feline spinal interneurones.
Topics: Action Potentials; Animals; Aspartic Acid; Cats; Dose-Response Relationship, Drug; Glutamates; Ibotenic Acid; Interneurons; Kainic Acid; Kinetics; Oxazoles; Pimelic Acids; Spinal Cord | 1978 |
The action of D-alpha-aminoadipate on excitatory amino acid receptors of rat thalamic neurones.
Topics: 2-Aminoadipic Acid; Action Potentials; Amino Acids; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Homocysteine; Kainic Acid; Neurons; Rats; Receptors, Drug; Thalamic Nuclei | 1978 |
Acute elevations of serum luteinizing hormone induced by kainic acid, N-methyl aspartic acid or homocysteic acid.
Topics: Animals; Aspartic Acid; Homocysteine; Hypothalamus; Kainic Acid; Kinetics; Luteinizing Hormone; Male; Pyrrolidines; Rats | 1978 |
The action of N-methyl-D-aspartic and kainic acids on motoneurones with emphasis on conductance changes [proceedings].
Topics: Animals; Aspartic Acid; Cats; Kainic Acid; Membrane Potentials; Motor Neurons; Neural Conduction; Pyrrolidines | 1978 |
[3H]D-aspartic acid release in brain slices of adult and aged Fischer 344 rates.
Topics: Aging; Animals; Aspartic Acid; Brain; Calcium Channels; Electric Stimulation; Hippocampus; Kainic Acid; Male; omega-Conotoxin GVIA; Peptides, Cyclic; Rats; Rats, Inbred F344; Temporal Lobe | 1992 |
Depression by sodium ions of calcium uptake mediated by non-N-methyl-D-aspartate receptors in cultured cerebellar neurons and correlation with evoked D-[3H]aspartate release.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ions; Kainic Acid; Neurons; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Tritium | 1992 |
Modulatory action of kainic acid on glutamate release from rat brain cortical synaptosomes.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Rats; Synaptosomes | 1992 |
Comparison of the release of exogenous and endogenous excitatory amino acids from rat cerebral cortex.
Topics: Animals; Aspartic Acid; Calcium; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Potassium; Radioisotope Dilution Technique; Rats; Tetrodotoxin; Tritium | 1992 |
N-methyl-D-aspartate exposure blocks glutamate toxicity in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Culture Media; Cytoplasmic Granules; Excitatory Amino Acid Antagonists; Glucose; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Ouabain; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensitivity and Specificity; Tritium | 1992 |
Domoic acid-containing toxic mussels produce neurotoxicity in neuronal cultures through a synergism between excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Bivalvia; Cells, Cultured; Drug Synergism; Glutamates; Glutamic Acid; Kainic Acid; Marine Toxins; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
A highly potent and selective N-methyl-D-aspartate receptor antagonist from the venom of the Agelenopsis aperta spider.
Topics: Agatoxins; Animals; Aspartic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spiders | 1992 |
Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: a microdialysis study of freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain Mapping; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Limbic System; Male; Rats; Rats, Wistar; Seizures; Serine; Synaptic Transmission | 1992 |
Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Brain Stem; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Locomotion; N-Methylaspartate; Nerve Net; Quisqualic Acid; Rats; Rats, Wistar; Serotonin; Spinal Cord | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Calcium; Cycloleucine; Egtazic Acid; Gene Library; Glutamates; Ibotenic Acid; Kainic Acid; Membrane Potentials; Molecular Sequence Data; Neurotoxins; Oligodeoxyribonucleotides; Oligonucleotide Probes; Oocytes; Polymerase Chain Reaction; Receptors, Glutamate; Restriction Mapping; Xenopus | 1992 |
Quantitative autoradiographic analysis of excitatory amino acid receptors in the cat spinal cord.
Topics: Animals; Aspartic Acid; Autoradiography; Cats; Kainic Acid; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Sodium; Spinal Cord | 1991 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Neurochemical characterization of excitotoxin lesions in the cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area.
Topics: Animals; Aspartic Acid; Female; Glutamates; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Ligands; Magnesium; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1991 |
DL-threo-3-hydroxyaspartate reduces NMDA receptor activation by glutamate in cultured neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; Kainic Acid; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Magnesium; Membrane Potentials; Neuroglia; Potassium; Retina; Sodium | 1991 |
Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Kainic Acid; Lysine; Male; N-Methylaspartate; Nerve Tissue Proteins; Phenazocine; Phencyclidine; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
Uneven distribution of excitatory amino acid receptors on ventral horn neurones of newborn rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dendrites; Dose-Response Relationship, Drug; Glutamates; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord | 1991 |
Stimulation of 22Na+ efflux from rat forebrain membrane vesicles by L-glutamic acid, L-aspartic acid and kainic acid.
Topics: Animals; Aspartic Acid; Cell Fractionation; Cell Membrane; Glutamates; Glutamic Acid; Kainic Acid; Male; Prosencephalon; Rats; Sodium; Temperature; Veratridine | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids evoke taurine release from cerebral cortex slices from adult and developing mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Potassium; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Secretory Rate; Stimulation, Chemical; Taurine | 1991 |
Quinolinic acid is a potent lipid peroxidant in rat brain homogenates.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Malondialdehyde; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Thiobarbiturates | 1991 |
Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead.
Topics: Animals; Aspartic Acid; Calcium; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Conductivity; Glycine; Hippocampus; Ion Channels; Kainic Acid; Lead; Learning Disabilities; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium Channels; Cell Membrane Permeability; Chick Embryo; Cochlear Nerve; Ganglia; Glutamates; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Potassium Channels; Sodium Channels | 1990 |
Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Cerebellum; Electric Conductivity; Glycine; Hydrogen-Ion Concentration; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Protons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA.
Topics: Amino Acids; Animals; Aspartic Acid; Bee Venoms; Brain; Chickens; Kainic Acid; Male; Membrane Potentials; Microinjections; N-Methylaspartate; Neurotoxins; Oocytes; Oxadiazoles; Poly A; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spermine; Wasp Venoms; Xenopus | 1990 |
Modulation of the N-methyl-D-aspartate channel by extracellular H+.
Topics: Animals; Aspartic Acid; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Hydrogen-Ion Concentration; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Interactions between substance P, calcitonin gene-related peptide, taurine and excitatory amino acids in the spinal cord.
Topics: Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Interactions; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Pain; Pain Measurement; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Self Mutilation; Spinal Cord; Substance P; Taurine | 1990 |
Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Glutamates; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1991 |
The actions of a conformationally restricted analogue of aspartic acid on mammalian spinal neurones.
Topics: Action Potentials; Animals; Aspartic Acid; Cycloleucine; Kainic Acid; Molecular Conformation; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Spinal Cord; Stereoisomerism | 1991 |
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Computer Simulation; Ibotenic Acid; Kainic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1990 |
NMDA receptors mediate poly- and monosynaptic potentials in motoneurons of rat embryos.
Topics: Animals; Aspartic Acid; Electrophysiology; Glutamates; Glutamic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synapses; Synaptic Transmission | 1990 |
Modulation of non-N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Granulocytes; Ibotenic Acid; Kainic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Failure of sigma-receptor ligands to reduce the excitatory actions of N-methyl-DL-aspartate on rat spinal neurons in-vivo.
Topics: Animals; Aspartic Acid; Haloperidol; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Stereoisomerism | 1990 |
Induction of locomotion in spinal tadpoles by excitatory amino acids and their agonists.
Topics: Animals; Anura; Aspartic Acid; Glutamates; Glutamic Acid; Kainic Acid; Locomotion; Motor Activity; N-Methylaspartate; Spinal Cord; Swimming | 1990 |
Acute- and long-term glutamate-mediated regulation of [Ca++]i in rat hippocampal pyramidal neurons in vitro.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ammonia; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Liver; Male; N-Methylaspartate; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |
Cortical neurons containing somatostatin- or parvalbumin-like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; Muscle Proteins; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Oxazoles; Parvalbumins; Somatostatin | 1990 |
Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Temperature; Time Factors | 1990 |
Glutamate- and aspartate-induced extracellular potassium and calcium shifts and their relation to those of kainate, quisqualate and N-methyl-D-aspartate in the isolated turtle cerebellum.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellum; Dose-Response Relationship, Drug; Extracellular Space; Glutamates; Glutamic Acid; In Vitro Techniques; Iontophoresis; Kainic Acid; Manganese; N-Methylaspartate; Potassium; Quisqualic Acid; Turtles | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Contribution of quisqualate/kainate and NMDA receptors to excitatory synaptic transmission in the rat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Electrophysiology; Evoked Potentials; Kainic Acid; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, Neurotransmitter; Visual Cortex | 1990 |
Decreased release of D-aspartate in the guinea pig spinal cord after lesions of the red nucleus.
Topics: Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Guinea Pigs; Kainic Acid; Male; Mesencephalon; Red Nucleus; Reticular Formation; Spinal Cord | 1991 |
Excitatory amino acid receptors on sustained retinal ganglion cells in the kitten during the critical period of development.
Topics: Action Potentials; Aging; Animals; Aspartic Acid; Cats; Kainic Acid; N-Methylaspartate; Oxadiazoles; Photic Stimulation; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Visual Pathways | 1990 |
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; Kainic Acid; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Phencyclidine; Pyrrolidinones; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Aspartic Acid; Autoradiography; Cerebral Cortex; Female; Glutamates; Humans; Ibotenic Acid; Kainic Acid; Male; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; Tritium | 1990 |
Glutamate receptor agonists cause efflux of endogenous neuroactive amino acids from cerebellar neurons in culture.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium Channels; Drug Antagonism; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Mice; N-Methylaspartate; Neurons; Nifedipine; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Stimulatory and inhibitory actions of excitatory amino acids on inositol phospholipid metabolism in rabbit retina. Evidence for a specific quisqualate receptor subtype associated with neurones.
Topics: Animals; Aspartic Acid; Calcium; Carbachol; Dose-Response Relationship, Drug; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, AMPA; Receptors, Neurotransmitter; Retina | 1990 |
6,7-Dinitroquinoxaline-2,3-dione blocks the cytotoxicity of N-methyl-D-aspartate and kainate, but not quisqualate, in cortical cultures.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Hippocampus; Kainic Acid; Ligands; N-Methylaspartate; Neurotoxins; Norepinephrine; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors.
Topics: Animals; Aspartic Acid; Guanidines; Haloperidol; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spiperone | 1990 |
Excitatory amino acids and cardiovascular apparatus: experimental studies on conscious rats with L-glutamate, N-methyl-D-aspartate, kainate and quisqualate.
Topics: Amino Acids; Animals; Aspartic Acid; Cardiovascular Physiological Phenomena; Cardiovascular System; Glutamates; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Synaptic Transmission | 1990 |
Glutamate-receptor-mediated regulation of the cytoplasmic free calcium level in cultured cerebellar granule cells.
Topics: Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cytoplasm; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kainic Acid; Kinetics; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1990 |
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Brain; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Male; N-Methylaspartate; Pipecolic Acids; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism | 1990 |
Pre- and postsynaptic excitatory action of glutamate agonists on frog vestibular receptors.
Topics: Afferent Pathways; Animals; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana esculenta; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Vestibule, Labyrinth | 1990 |
Excitatory amino acid response in isolated nucleus tractus solitarii neurons of the rat.
Topics: Amino Acids; Animals; Aspartic Acid; Electrophysiology; Glycine; In Vitro Techniques; Kainic Acid; Medulla Oblongata; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
N-methyl-D-aspartate antagonism and phencyclidine-like activity: a drug discrimination analysis.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Injections, Intraperitoneal; Kainic Acid; Male; Mice; N-Methylaspartate; Phencyclidine; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains | 1990 |
Role of endogenous taurine on the glutamate analogue-induced neurotoxicity in the rat hippocampus in vivo.
Topics: Animals; Aspartic Acid; Extracellular Space; Hippocampus; Kainic Acid; N-Methylaspartate; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Sucrose; Taurine | 1990 |
Microionophoretic study with milacemide, a glycine precursor, on mammalian central nervous system cells.
Topics: Acetamides; Animals; Aspartic Acid; Brain; Cats; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Kainic Acid; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid | 1990 |
GABA does not protect cerebro-cortical cultures against excitotoxic cell death.
Topics: Animals; Aspartic Acid; Cell Survival; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Oxadiazoles; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
Neuropeptide Y selectively potentiates N-methyl-D-aspartate-induced neuronal activation.
Topics: Animals; Aspartic Acid; Drug Synergism; Haloperidol; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Neuropeptide Y; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
Electrophysiology of glutamate and sodium co-transport in a glial cell of the salamander retina.
Topics: Ambystoma; Animals; Aspartic Acid; Binding Sites; Biological Transport, Active; Dose-Response Relationship, Drug; Glutamates; Ion Channel Gating; Kainic Acid; Membrane Potentials; Retina; Sodium | 1990 |
Comparison of anticonvulsant effect of ethanol against NMDA-, kainic acid- and picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Ethanol; Kainic Acid; Male; N-Methylaspartate; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1990 |
Kainic acid responses and toxicity show pronounced Ca2+ dependence.
Topics: Animals; Aspartic Acid; Calcium; Drug Interactions; In Vitro Techniques; Ion Channels; Iontophoresis; Kainic Acid; Limbic System; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1985 |
Evidence that excitatory amino acids not only activate the receptor channel complex but also lead to use-dependent block.
Topics: Amino Acids; Animals; Aspartic Acid; Chick Embryo; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Spinal Cord | 1986 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Voltage-dependent block of excitatory amino acid currents by pentobarbital.
Topics: Animals; Aspartic Acid; Cells, Cultured; Hippocampus; Ion Channels; Kainic Acid; Membrane Potentials; Mice; Nerve Block; Neural Conduction; Pentobarbital | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Electric Conductivity; Glutamates; Glutamic Acid; Hippocampus; Ion Channels; Kainic Acid; Ketamine; Membrane Potentials; Mice; N-Methylaspartate; Spinal Cord | 1987 |
Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
Topics: Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Ion Channels; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Visual Cortex | 1988 |
The effect of intracellular tetraethylammonium ions on the reversal potential of monosynaptic EPSPs and excitatory amino acids in cultured spinal cord neurones.
Topics: Animals; Aspartic Acid; Cells, Cultured; Dendrites; Ion Channels; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Tetraethylammonium Compounds | 1988 |
Effects of kainic acid lesions in lateral geniculate nucleus: activity dependence of retrograde axonal transport of fluorescent dyes.
Topics: Amidines; Animals; Aspartic Acid; Axonal Transport; Benzimidazoles; Electric Stimulation; Female; Fluorescent Dyes; Geniculate Bodies; Kainic Acid; Proteins; Rats; Rats, Inbred Strains; Retinal Ganglion Cells; Superior Colliculi; Visual Cortex; Visual Pathways | 1988 |
Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Differences in the pore sizes of the N-methyl-D-aspartate and kainate cation channels.
Topics: Animals; Aspartic Acid; Brain; Calcium; Cations; Cell Membrane Permeability; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Strontium | 1988 |
N-methyl-D-aspartate activates different channels than do kainate and quisqualate.
Topics: Animals; Aspartic Acid; Brain Chemistry; Electric Conductivity; Female; Ion Channels; Kainic Acid; Magnesium; Male; N-Methylaspartate; Oocytes; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1989 |
Ethanol inhibits NMDA-activated ion current in hippocampal neurons.
Topics: 1-Butanol; Aspartic Acid; Butanols; Calcium Channels; Chloride Channels; Chlorides; Electric Conductivity; Ethanol; gamma-Aminobutyric Acid; Hippocampus; Humans; Ion Channels; Kainic Acid; Membrane Proteins; Methanol; N-Methylaspartate; Neurons; Oxadiazoles; Pentanols; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels | 1989 |
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
Topics: Analgesia; Animals; Aspartic Acid; Baclofen; Behavior, Animal; Bicuculline; Kainic Acid; Male; Mice; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, GABA-A; Spinal Cord; Substance P | 1989 |
Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured purkinje neurons.
Topics: Action Potentials; Animals; Aspartic Acid; Cadmium; Calcium; Cations, Divalent; Choline; Electric Conductivity; Ion Channels; Kainic Acid; Kynurenic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Sucrose; Tetrodotoxin | 1989 |
Multiple conductance channels in type-2 cerebellar astrocytes activated by excitatory amino acids.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebellum; Convulsants; Electric Conductivity; Evoked Potentials; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Synaptic Transmission | 1989 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Cloning by functional expression of a member of the glutamate receptor family.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Brain Chemistry; Cloning, Molecular; DNA; Electrophysiology; Gene Expression; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Molecular Sequence Data; Molecular Weight; N-Methylaspartate; Oocytes; Plasmids; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA; Tissue Distribution; Transcription, Genetic; Transfection; Xenopus | 1989 |
Excitotoxicity of NMDA and kainic acid is modulated by nigrostriatal dopaminergic fibres.
Topics: Animals; Aspartic Acid; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Glutamate Decarboxylase; Hydroxydopamines; Kainic Acid; N-Methylaspartate; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
[Excitotoxic damage of the hippocampus in the rat: involvement of N-methyl-D-aspartate receptors].
Topics: Animals; Aspartic Acid; Hippocampus; Illicit Drugs; Kainic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains | 1989 |
Quisqualic acid modulates kainate responses in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Interactions; Kainic Acid; Nitroprusside; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Effects of excitatory amino acid receptor antagonists and agonists on suprachiasmatic nucleus responses to retinohypothalamic tract volleys.
Topics: Animals; Aspartic Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Optic Nerve; Pipecolic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Suprachiasmatic Nucleus | 1989 |
In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.
Topics: Animals; Aspartic Acid; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Gene Expression Regulation; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Phencyclidine; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Transcription, Genetic | 1989 |
Pharmacological characterization of the glutamate receptor in cultured astrocytes.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Direct activation of gonadotropin-releasing hormone secretion through different receptors to neuroexcitatory amino acids.
Topics: Animals; Aspartic Acid; Hypothalamus; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Pituitary Hormone-Releasing Hormones; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo.
Topics: Action Potentials; Animals; Aspartic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine; Thalamus | 1989 |
Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage.
Topics: Animals; Aspartic Acid; Calpain; Colchicine; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Peptide Hydrolases; Rats; Rats, Inbred Strains; Spectrin; Time Factors; Tissue Distribution | 1989 |
Pulsatile release of gonadotropin-releasing hormone from hypothalamic explants is restrained by blockade of N-methyl-D,L-aspartate receptors.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Hormone-Releasing Hormones; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Neurotoxicity of excitatory amino acid receptor agonists in young rat hippocampal slices.
Topics: Animals; Aspartic Acid; Female; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Time Factors | 1989 |
Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors.
Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Biological Assay; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Xenopus laevis | 1989 |
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Blotting, Northern; Convulsants; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Immunoblotting; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Nucleic Acid Hybridization; Pentylenetetrazole; Picrotoxin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Seizures; Transcription Factors | 1989 |
Ca2+-mediated neuronal death in rat brain neuronal cultures by veratridine: protection by flunarizine.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Glutamates; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Rats; Sodium Channels; Tetrodotoxin; Veratridine; Veratrine | 1989 |
A quantitative description of excitatory amino acid neurotransmitter responses on cultured embryonic Xenopus spinal neurons.
Topics: Animals; Aspartic Acid; Embryo, Nonmammalian; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus laevis | 1989 |
Properties of excitatory amino acid receptors on sustained ganglion cells in the cat retina.
Topics: Action Potentials; Animals; Aspartic Acid; Cats; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells | 1989 |
Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: further evidence that toxicity of domoic acid involves kainate receptor activation.
Topics: Animals; Aspartic Acid; Colchicine; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1989 |
Regulation of N-methyl-D-aspartate receptors revealed by intracellular dialysis of murine neurones in culture.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Dialysis; Egtazic Acid; Electric Conductivity; Electrophysiology; Intracellular Membranes; Kainic Acid; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Non-N-methyl-D-aspartate receptors may mediate ipsilateral excitation at lateral superior olivary synapses.
Topics: Acoustic Stimulation; Action Potentials; Animals; Aspartic Acid; Auditory Pathways; Chinchilla; Dose-Response Relationship, Drug; Functional Laterality; Kainic Acid; N-Methylaspartate; Olivary Nucleus; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Kainate evokes the release of endogenous glycine from striatal neurons in primary culture.
Topics: Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Glutamate receptor subtypes may be classified into two major categories: a study on Xenopus oocytes injected with rat brain mRNA.
Topics: Animals; Aspartic Acid; Brain Chemistry; Electrophysiology; Glutamates; Homocysteine; Ibotenic Acid; Kainic Acid; Microinjections; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1989 |
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
Attenuation of neurotoxicity following anoxia or glutamate receptor activation in EGF- and hippocampal extract-treated neuronal cultures.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Growth Substances; Hippocampus; Hypoxia, Brain; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Oxygen; Potassium Cyanide; Rats; Receptors, Adrenergic, beta; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Expression of excitatory amino acid receptors by cerebellar cells of the type-2 astrocyte cell lineage.
Topics: Animals; Aspartic Acid; Astrocytes; Autoradiography; Cell Line; Cerebellum; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
L-[3H]glutamate binding to a membrane preparation from crayfish muscle.
Topics: Animals; Aspartic Acid; Astacoidea; Binding, Competitive; Calcium; Cell Membrane; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Muscles; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism | 1989 |
Modulation of dendritic release of dopamine by N-methyl-D-aspartate receptors in rat substantia nigra.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dendrites; Dopamine; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substantia Nigra; Tetrodotoxin | 1989 |
Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions.
Topics: Animals; Aspartic Acid; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptide Y; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Somatostatin | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Excitatory amino acid-evoked release of [3H]GABA from hippocampal neurons in primary culture.
Topics: Animals; Aspartic Acid; Cells, Cultured; Ethers; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Ionomycin; Kainic Acid; N-Methylaspartate; Rats; Rats, Inbred Strains; Veratridine; Zinc | 1989 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hypoglycemia; Ibotenic Acid; Insulin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Regulation of Ca++ influx into striatal neurons by kainic acid.
Topics: Animals; Aspartic Acid; Calcium; Calcium Channels; Corpus Striatum; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Potassium; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Auditory nerve neurotransmitter acts on a kainate receptor: evidence from intracellular recordings in brain slices from mice.
Topics: Action Potentials; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Mice; Mice, Inbred CBA; N-Methylaspartate; Receptors, Glutamate; Receptors, Neurotransmitter; Vestibulocochlear Nerve | 1989 |
Evidence that glutamate mediates axon-to-Schwann cell signaling in the squid.
Topics: Action Potentials; Animals; Aspartic Acid; Axons; Cell Communication; Convulsants; Decapodiformes; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Schwann Cells | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using L-[3H]glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Software; Tritium | 1989 |
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
Glutamate receptor activation in cultured cerebellar granule cells increases cytosolic free Ca2+ by mobilization of cellular Ca2+ and activation of Ca2+ influx.
Topics: Animals; Aspartic Acid; Benzofurans; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Cytosol; Fluorescent Dyes; Fura-2; Glutamates; Glutamic Acid; Inositol Phosphates; Kainic Acid; Mice; N-Methylaspartate; Receptors, Glutamate; Receptors, Neurotransmitter; Spectrometry, Fluorescence | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Lack of excitatory amino acid-induced effects on calcium fluxes measured with 45Ca2+ in rat cerebral cortex synaptosomes.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Temperature | 1989 |
Extracellular taurine increase in rat hippocampus evoked by specific glutamate receptor activation is related to the excitatory potency of glutamate agonists.
Topics: Action Potentials; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
Quantitative physiological characterization of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kainic Acid; Mathematics; N-Methylaspartate; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Synapses | 1989 |
Inhibition of rat brain glutamate receptors by philanthotoxin.
Topics: Animals; Aspartic Acid; Bee Venoms; Brain; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Wasp Venoms; Xenopus | 1989 |
Changes of the membrane potential in striatal synaptoneurosome, synaptosome and membrane sac preparations induced by glutamate, kainate and aspartate as measured with a cyanine dye DiS-C2-(5).
Topics: Animals; Aspartic Acid; Corpus Striatum; Dithiazanine; Fluorescent Dyes; Glutamates; Glutamic Acid; Guinea Pigs; Kainic Acid; Membrane Potentials; Synaptosomes | 1989 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the neonatal rat hippocampus by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Carbachol; Chlorides; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol; Kainic Acid; Kinetics; Lithium; Lithium Chloride; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Excitatory amino acid receptor-mediated activation of solitarial deglutitive loci.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Deglutition; Dipeptides; Esophagus; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Pharynx; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Inhibition of N-methyl-D-aspartate- and kainic acid-induced neurotransmitter release by omega-conotoxin GVIA.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mollusk Venoms; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; omega-Conotoxin GVIA; Rats; Rats, Inbred Strains | 1989 |
Evidence for evoked release of adenosine and glutamate from cultured cerebellar granule cells.
Topics: Adenosine; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Kainic Acid; Mice; Potassium Chloride; Tritium | 1989 |
Selective inhibition of excitatory amino acids by divalent cations. A novel means for distinguishing N-methyl-D-aspartic acid-, kainate- and quisqualate-mediated actions in the mouse spinal cord.
Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; Male; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord; Zinc | 1989 |
Glial uptake of excitatory amino acids influences neuronal survival in cultures of mouse hippocampus.
Topics: Action Potentials; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Culture Media; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroglia; Phosphopyruvate Hydratase; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
The action of N-methyl-D-aspartic acid on mouse spinal neurones in culture.
Topics: Action Potentials; Animals; Aspartic Acid; Cells, Cultured; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Spinal Cord; Time Factors | 1985 |
Release of D-[3H]aspartic acid from the rat striatum. Effect of veratridine-evoked depolarization, fronto-parietal cortex ablation, and striatal lesions with kainic acid.
Topics: Animals; Aspartic Acid; Calcium; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Potentials; Neural Pathways; Neurotransmitter Agents; Parietal Lobe; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Veratridine | 1985 |
Homocysteic acid: convulsant action of stereoisomers in mice.
Topics: Animals; Aspartic Acid; Convulsants; Homocysteine; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Seizures; Stereoisomerism | 1989 |
In vivo electrochemical studies of the effects of N-methyl-D-aspartate (NMDA) on dopamine nerve terminals in the neostriatum of the anesthetized rat.
Topics: Anesthesia; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Electrochemistry; Kainic Acid; Male; N-Methylaspartate; Nerve Endings; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1989 |
Excitatory amino acids interfere with normal eye growth in posthatch chick.
Topics: Animals; Anterior Chamber; Aspartic Acid; Chickens; Eye; Kainic Acid; N-Methylaspartate; Organ Size; Oxadiazoles; Quisqualic Acid; Retina; Time Factors | 1989 |
Excitotoxin-induced myocardial necrosis.
Topics: Animals; Aspartic Acid; Blood Pressure; Cardiomyopathies; Heart Rate; Hypothalamus, Middle; Injections; Injections, Intraventricular; Kainic Acid; Male; Myocardium; N-Methylaspartate; Necrosis; Rats; Rats, Inbred Strains | 1989 |
Kynurenic acid microinjected into the nucleus tractus solitarius of rat blocks the arterial baroreflex but not responses to glutamate.
Topics: Acetylcholine; Animals; Arteries; Aspartic Acid; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Histocytochemistry; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Reflex | 1989 |
AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Oxazoles; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Substantia Innominata | 1989 |
Neurochemical studies on quinolone antibiotics: effects on glutamate, GABA and adenosine systems in mammalian CNS.
Topics: 4-Quinolones; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Infective Agents; Aspartic Acid; Brain Chemistry; Calcium; Chlorides; Diazepam; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Kainic Acid; Male; Rats; Rats, Inbred Strains | 1989 |
Selection of a pure cerebellar granule cell culture by kainate treatment.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Kainic Acid; Mice; Neurons | 1989 |
Cultured cerebellar cells as an in vitro model of excitatory amino acid receptor function.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Models, Neurological; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Narcotics; Nociceptors; Oxadiazoles; Pain; Phencyclidine; Phentolamine; Quisqualic Acid; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1987 |
Functional and biochemical characteristics of a putative quisqualate-type receptor in rat striatum: effect of brain lesions.
Topics: Animals; Aspartic Acid; Brain; Cerebral Cortex; Convulsants; Corpus Striatum; Dopamine; Glutamates; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1986 |
New quinoxalinediones show potent antagonism of quisqualate responses in cultured mouse cortical neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Drug; Sodium | 1988 |
The interaction of agonists and noncompetitive antagonists at the excitatory amino acid receptors in rat retinal ganglion cells in vitro.
Topics: Animals; Aspartic Acid; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Electrophysiology; Kainic Acid; N-Methylaspartate; Osmolar Concentration; Phencyclidine; Receptors, Amino Acid; Receptors, Cell Surface | 1988 |
Release of [3H]norepinephrine from rat hippocampal slices by N-methyl-D-aspartate: comparison of the inhibitory effects of Mg2+ and MK-801.
Topics: Amino Acids; Animals; Aspartic Acid; Convulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1988 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Oxadiazoles; Pilocarpine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Seizures | 1988 |
Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo.
Topics: Animals; Aspartic Acid; Brain; Calpain; Cytosol; Enzyme Activation; Erythrocytes; Humans; Isoenzymes; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Peptide Mapping; Rats; Rats, Inbred Strains; Spectrin; Substrate Specificity | 1988 |
Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum.
Topics: Animals; Aspartic Acid; Corpus Striatum; Female; Glutamates; Glutamic Acid; Kainic Acid; Rats; Rats, Inbred Strains | 1985 |
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1985 |
Roles of aspartate and glutamate in synaptic transmission in rabbit retina. I. Outer plexiform layer.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Neurotransmitter Agents; Rabbits; Retina; Synaptic Transmission | 1985 |
Schistosoma mansoni, S. japonicum, and S. haematobium: permeability to acidic amino acids and effect of separated and unseparated adults.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Copulation; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; Schistosoma haematobium; Schistosoma japonicum; Schistosoma mansoni; Sex Factors; Time Factors | 1985 |
Excitatory effects of L-glutamate and some analogs on isolated horizontal cells from the catfish retina.
Topics: Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Retina | 1985 |
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist?
Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism | 1985 |
Effects of excitatory amino acids on calcium transport by brain membranes.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Brain Chemistry; Calcium; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Neurotransmitter Agents; Synaptosomes | 1985 |
Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Calcium; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Nicotinic Acids; Nimodipine; Pyrrolidines; Retina | 1985 |
The effects of putative amino acid neurotransmitters on somata isolated from neurons of the locust central nervous system.
Topics: Action Potentials; Animals; Aspartic Acid; Cysteine; Female; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamic Acid; Grasshoppers; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotransmitter Agents; Taurine | 1985 |
Anticonvulsant properties of 3-hydroxy-2-quinoxalinecarboxylic acid, a newly found antagonist of excitatory amino acids.
Topics: Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Structure-Activity Relationship | 1985 |
Cellular uptake disguises action of L-glutamate on N-methyl-D-aspartate receptors. With an appendix: diffusion of transported amino acids into brain slices.
Topics: Aging; Animals; Aspartic Acid; Biological Transport; Brain; Cyclic GMP; Diffusion; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1985 |
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Effects of bath-applied excitatory amino acids and their analogs on spinal interneurons of the lamprey.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; Glycine; Homocysteine; In Vitro Techniques; Interneurons; Kainic Acid; Lampreys; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord | 1985 |
Stimulation of photoreceptor disc shedding and pigment epithelial phagocytosis by glutamate, aspartate, and other amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Cell Membrane; Choline; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Ouabain; Phagocytosis; Photic Stimulation; Photoreceptor Cells; Pigment Epithelium of Eye; Potassium Chloride; Xenopus laevis | 1985 |
L-Homocysteic acid as an alternative cytotoxin for studying glutamate-induced cellular degeneration of Huntington's disease and normal skin fibroblasts.
Topics: Aspartic Acid; Cell Survival; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Homocysteine; Humans; Huntington Disease; In Vitro Techniques; Isomerism; Kainic Acid; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Skin; Time Factors | 1985 |
Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.
Topics: Animals; Aspartic Acid; Drug Synergism; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Synaptic Transmission | 1985 |
Kainic acid differentially affects the synaptosomal release of endogenous and exogenous amino acidic neurotransmitters.
Topics: Animals; Aspartic Acid; Calcium; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Goldfish; Hippocampus; Kainic Acid; Magnesium; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Peptides derived from kainic acid as antagonists of N-methyl-D-aspartate-induced neuroexcitation in rat brain.
Topics: Animals; Aspartic Acid; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1985 |
Excitatory and inhibitory responses of Purkinje cells, in the rat cerebellum in vivo, induced by excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Neurochemical relation between excitatory and inhibitory amino acids in hippocampus.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains | 1985 |
A dipeptide derived from kainic and L-glutamic acids: a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Corpus Striatum; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Picrotoxin; Quisqualic Acid; Rats; Seizures; Sodium | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Kainic acid-induced changes of extracellular amino acid levels, evoked potentials and EEG activity in the rabbit olfactory bulb.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Electroencephalography; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Olfactory Bulb; Rabbits; Time Factors | 1985 |
The role of putative excitatory amino acid neurotransmitters in the initiation of locomotion in the lamprey spinal cord. II. The effects of amino acid uptake inhibitors.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Lampreys; Locomotion; N-Methylaspartate; Neurotransmitter Agents; Spinal Cord; Synaptic Transmission | 1985 |
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1986 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
Excitatory amino acid analogs evoke release of endogenous amino acids and acetyl choline from chick retina in vitro.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Calcium; Chickens; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Potassium; Quisqualic Acid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Sodium; Stimulation, Chemical | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
Effect of selective kainate lesions on the release of glutamate and aspartate from chick retina.
Topics: Animals; Aspartic Acid; Chickens; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; Microinjections; Retina | 1986 |
The binding of acidic amino acids to snail, Helix aspersa, periesophagic ring membranes reveals a single high-affinity glutamate/kainate site.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Cysteine; Ganglia; Glutamates; Glutamic Acid; Helix, Snails; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Kinetics; Neurotransmitter Agents; Osmolar Concentration | 1986 |
Effects of topically applied excitatory amino acids on evoked potentials and single cell activity in rat cerebral cortex.
Topics: Administration, Topical; Amino Acids; Animals; Aspartic Acid; Carbachol; Cerebral Cortex; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tetrodotoxin | 1986 |
Activity of beta-kainic acid on neocortical neurons in vivo and hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Hippocampus; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Receptors, Neurotransmitter; Valine | 1986 |
N-methyl D-aspartate acts as an antagonist of the photoreceptor transmitter in the carp retina.
Topics: Animals; Aspartic Acid; Carps; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurotransmitter Agents; Photic Stimulation; Photoreceptor Cells; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina | 1986 |
Pharmacologically distinct glutamate receptors on cerebellar granule cells.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1986 |
Effects of D-aspartate on excitatory amino acid-induced release of [3H]GABA from goldfish retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Goldfish; Kainic Acid; Oxadiazoles; Quisqualic Acid; Retina; Tritium | 1986 |
Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex.
Topics: Animals; Aspartic Acid; Bicuculline; Carbachol; Glutamates; Glutamic Acid; Kainic Acid; Limbic System; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1986 |
Comparative actions of quisqualate and N-methyl-D-aspartate, excitatory amino acid agonists, on guinea-pig cochlear potentials.
Topics: Action Potentials; Animals; Aspartic Acid; Cochlea; Dose-Response Relationship, Drug; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Vestibulocochlear Nerve | 1986 |
Characterization of the inhibition of excitatory amino acid-induced neurotransmitter release in the rat striatum by phencyclidine-like drugs.
Topics: Animals; Aspartic Acid; Corpus Striatum; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1986 |
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid | 1986 |
The effect of kainic, quinolinic and beta-kainic acids on the release of endogenous amino acids from rat brain slices.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1986 |
Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Autoradiography; Female; Glutamates; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Male; Middle Aged; N-Methylaspartate; Neuronal Plasticity; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
On the role of seizure activity and endogenous excitatory amino acids in mediating seizure-associated hippocampal damage.
Topics: Acetylcholine; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cell Survival; Dendrites; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kainic Acid; Neurotransmitter Agents; Seizures; Time Factors | 1986 |
Cellular origins of cyclic GMP responses to excitatory amino acid receptor agonists in rat cerebellum in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Nitroprusside; Purkinje Cells; Rats; Tetrodotoxin | 1987 |
Glutamate receptor agonists release [3H]GABA preferentially from horizontal cells.
Topics: Animals; Aspartic Acid; Autoradiography; Chickens; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Rana pipiens; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Retina | 1986 |
In vivo studies on the extracellular, and veratrine-releasable, pools of endogenous amino acids in the rat striatum: effects of corticostriatal deafferentation and kainic acid lesion.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Denervation; Ethanolamines; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; Rats; Rats, Inbred Strains; Taurine; Veratrine | 1987 |
Cellular origins of endogenous amino acids released into the extracellular fluid of the rat striatum during severe insulin-induced hypoglycemia.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Denervation; Ethanolamines; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hypoglycemia; Insulin; Kainic Acid; Male; Rats; Rats, Inbred Strains; Taurine | 1987 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Structure-Activity Relationship; Valine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Excitatory amino acid receptors and ischemic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kainic Acid; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1987 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc | 1987 |
The effects of prolonged superfusions with acidic amino acids and their agonists on field potentials and horizontal cell photoresponses in the turtle retina.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Perfusion; Photoreceptor Cells; Retina; Turtles | 1987 |
Joro spider venom: glutamate agonist and antagonist on the rod retina of the dogfish.
Topics: Animals; Arthropod Venoms; Aspartic Acid; Dogfish; Glutamates; Glutamic Acid; Iontophoresis; Kainic Acid; Photic Stimulation; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Spider Venoms; Spiders | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Excitatory amino acid receptor potency and subclass specificity of sulfur-containing amino acids.
Topics: Amino Acids, Sulfur; Aminobutyrates; Animals; Aspartic Acid; Brain; Chick Embryo; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Sodium; Synaptic Membranes | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
AMPA is a powerful neurotoxin in the chicken retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body | 1987 |
In vivo microdialysis studies on the effects of decortication and excitotoxic lesions on kainic acid-induced calcium fluxes, and endogenous amino acid release, in the rat striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cerebral Cortex; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; Neurons; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Taurine | 1987 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
The mouse neocortical slice: preparation and responses to excitatory amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Cerebral Cortex; Corpus Callosum; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred Strains; N-Methylaspartate; Ouabain; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Tetrodotoxin | 1987 |
Glutamate receptor subtypes in cultured cerebellar neurons: modulation of glutamate and gamma-aminobutyric acid release.
Topics: Animals; Aspartic Acid; Calcium; Cations; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium | 1987 |
Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse.
Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Cerebellum; Glutamates; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Colchicine; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Chick Embryo; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Ligands; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina | 1987 |
Potentiation by kainate of excitatory amino acid release in striatum: complementary in vivo and in vitro experiments.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Corpus Striatum; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Potassium; Rats; Rats, Inbred Strains; Taurine; Tetrodotoxin | 1988 |
Kainic acid inhibits the synaptosomal plasma membrane glutamate carrier and allows glutamate leakage from the cytoplasm but does not affect glutamate exocytosis.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Carrier Proteins; Cell Membrane; Cytoplasm; Exocytosis; Female; Glutamate Dehydrogenase; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Guinea Pigs; Kainic Acid; Male; Permeability; Symporters; Synaptosomes | 1988 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Excitatory amino acid-evoked membrane currents and excitatory synaptic transmission in lamprey reticulospinal neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Stem; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Lampreys; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Spinal Cord; Synapses; Synaptic Transmission | 1988 |
Utilization of the synthetic phosphagen cyclocreatine phosphate by a simple brain model during stimulation by neuroexcitatory amino acids.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chick Embryo; Glutamates; Glutamic Acid; Homocysteine; Imidazolidines; Kainic Acid; Magnesium; N-Methylaspartate; Phosphocreatine | 1988 |
Enhancement of the oxygen consumption in the hippocampal slices of the guinea pig induced by glutamate and its related substances.
Topics: Action Potentials; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxygen Consumption | 1988 |
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: autoradiographic and electrophysiological evidence.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Autoradiography; Electric Stimulation; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reaction Time; Valine; Ventromedial Hypothalamic Nucleus | 1988 |
NMDA- and kainate-evoked GABA release from striatal neurones differentiated in primary culture: differential blocking by phencyclidine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
L-glutamate-induced depolarization in solitary photoreceptors: a process that may contribute to the interaction between photoreceptors in situ.
Topics: Animals; Aspartic Acid; Axons; Dose-Response Relationship, Drug; Electric Conductivity; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid; Sodium; Turtles | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen.
Topics: Adenosine; Animals; Aspartic Acid; Baclofen; Calcium; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Veratridine | 1988 |
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
The effect of an uptake inhibitor (dihydrokainate) on endogenous excitatory amino acids in the lamprey spinal cord as revealed by microdialysis.
Topics: Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Lampreys; Neurotransmitter Agents; Reference Values; Spinal Cord | 1988 |
Effect of inhibitors of gamma-glutamyl transpeptidase on the uptake of glutamate and aspartate into cultured astroglial cells from the glycogen body and cerebral hemispheres of the embryonic chick.
Topics: Animals; Aspartic Acid; Astrocytes; Biological Transport; Borates; Brain; Cells, Cultured; Chick Embryo; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Serine; Spinal Cord | 1988 |
Epinephrine and norepinephrine modulate neuronal responses to excitatory amino acids and agonists in frog spinal cord.
Topics: Amino Acids; Animals; Aspartic Acid; Epinephrine; Glutamates; Glutamic Acid; In Vitro Techniques; Isoproterenol; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rana pipiens; Reference Values; Spinal Cord; Yohimbine | 1987 |
Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus laevis | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Lithium; Lithium Chloride; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1988 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells | 1988 |
Acute tachycardia and pressor effects following injections of kainic acid into the antero-dorsal medial hypothalamus.
Topics: Animals; Aspartic Acid; Blood Pressure; Heart Rate; Hypothalamus; Injections; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains | 1987 |
The action of quinolinate in the rat spinal cord in vitro.
Topics: Animals; Anticonvulsants; Aspartic Acid; Convulsants; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
Excitatory amino acid pharmacology of the auditory nerve and nucleus magnocellularis of the chicken.
Topics: Amino Acids; Animals; Aspartic Acid; Auditory Pathways; Baclofen; Brain Stem; Chick Embryo; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Vestibulocochlear Nerve | 1985 |
Anticonvulsant action of stereoisomers of gamma-glutamylaminomethylsulphonic acid in mice.
Topics: Animals; Anticonvulsants; Aspartic Acid; Glutamates; Glutamine; Kainic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1985 |
Effects of unilateral lesion of the inferior olive on L-[3H] aspartate receptors binding in synaptic membranes of cat cerebellar cortex.
Topics: Animals; Aspartic Acid; Cats; Cerebellar Cortex; Kainic Acid; Kinetics; Motor Activity; Neural Pathways; Olivary Nucleus; Posture; Receptors, Amino Acid; Receptors, Neurotransmitter | 1985 |
Novel kainic acid analogues. Effects on cyclic GMP content of adult rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship | 1986 |
In vitro neurotoxicity of excitatory acid analogues during cerebellar development.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Female; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1986 |
Is Metaphit a phencyclidine antagonist? Studies with ketamine, phencyclidine and N-methylaspartate.
Topics: Action Potentials; Animals; Aspartic Acid; Depression, Chemical; Drug Interactions; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1986 |
Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: dependence on calcium concentration.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Golgi Apparatus; Granulocytes; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Osmolar Concentration; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1986 |
An animal model for neuron-specific spinal cord lesions by the microinjection of N-methylaspartate, kainic acid, and quisqualic acid.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Forelimb; Ganglia, Spinal; Hindlimb; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission | 1985 |
Excitatory synaptic transmission between interneurons and motoneurons in chick spinal cord cell cultures.
Topics: Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Interneurons; Kainic Acid; Motor Neurons; Neuromuscular Junction; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1986 |
Modulation of embryonic chick motoneuron glutamate sensitivity by interneurons and agonists.
Topics: Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electrophysiology; Glutamates; Interneurons; Kainic Acid; Motor Neurons; Neuromuscular Junction; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission | 1986 |
Excitatory amino acid antagonists as novel anticonvulsants.
Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Glutamates; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship | 1986 |
Excitatory amino acids and divalent cations in the kindling model of epilepsy.
Topics: Animals; Aspartic Acid; Calcium; Calcium-Binding Proteins; Cations, Divalent; Epilepsy; Glutamates; Hippocampus; Kainic Acid; Kindling, Neurologic; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Zinc | 1986 |
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Muscle Relaxants, Central; N-Methylaspartate; Oxadiazoles; Piperazines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Time Factors | 1987 |
After-hyperpolarizations produced in frog motoneurons by excitatory amino acid analogues.
Topics: 2,4-Dinitrophenol; Animals; Aspartic Acid; Dinitrophenols; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Ouabain; Oxadiazoles; Potassium; Quisqualic Acid; Ranidae; Sodium; Synaptic Transmission | 1987 |
Evidence that antagonism at non-NMDA receptors results in anticonvulsant action.
Topics: Animals; Anticonvulsants; Aspartic Acid; Glutamates; Glutamine; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
A comparison of excitatory amino acid antagonists acting at primary afferent C fibres and motoneurones of the isolated spinal cord of the rat.
Topics: Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1987 |
Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Kainic Acid; Levorphanol; Mice; Morphinans; N-Methylaspartate; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
The effect of two novel dipeptide antagonists of excitatory amino acid neurotransmission on the high pressure neurological syndrome in the rat.
Topics: Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Glutamine; High Pressure Neurological Syndrome; Kainic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Excitatory amino acid neurotoxicity in the hippocampal slice preparation.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Microscopy, Electron; N-Methylaspartate; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
Excitatory amino acids and rod photoreceptor disc shedding: analysis using specific agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Light; N-Methylaspartate; Oxadiazoles; Phagosomes; Photoreceptor Cells; Pigment Epithelium of Eye; Quisqualic Acid; Rana pipiens; Xenopus laevis | 1988 |
Piriform cortex brain slices: techniques for isolation of synaptic inputs.
Topics: Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Dendrites; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Synapses | 1988 |
Regulation of seizure threshold by excitatory amino acids in the striatum and entopeduncular nucleus of rats.
Topics: Animals; Aspartic Acid; Corpus Striatum; Globus Pallidus; Kainic Acid; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1988 |
A voltage clamp study of the glutamate responsive neuromuscular junction in Drosophila melanogaster.
Topics: Action Potentials; Alcohols; Amino Acids; Animals; Aspartic Acid; Drosophila melanogaster; Electrodes; Glutamates; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid | 1988 |
Putative serotonergic bipolar and amacrine cells in the chicken retina.
Topics: 5,7-Dihydroxytryptamine; Animals; Aspartic Acid; Chickens; Fluorescent Antibody Technique; Kainic Acid; N-Methylaspartate; Neurotoxins; Retina; Serotonin | 1988 |
Some properties of membrane current fluctuations induced by kainate, quisqualate, and NMDA in cultured septal neurons of rat.
Topics: Animals; Aspartic Acid; Brain; Cells, Cultured; Convulsants; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats | 1988 |
Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats.
Topics: Acetylcholinesterase; Amino Acids; Animals; Aspartic Acid; Basal Ganglia; Behavior, Animal; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Female; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substantia Innominata | 1987 |
Systemic administration of MK-801 prevents N-methyl-D-aspartate-induced neuronal degeneration in rat brain.
Topics: Animals; Aspartic Acid; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Rats; Rats, Inbred Strains | 1987 |
Responses of pyriform cortex neurons to excitatory amino acids: voltage dependence, conductance changes, and effects of divalent cations.
Topics: Animals; Aspartic Acid; Brain; Cations, Divalent; Convulsants; Electric Stimulation; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats | 1987 |
Folic acid protects chick retinal neurons against the neurotoxic action of excitatory amino acids.
Topics: Animals; Aspartic Acid; Chickens; Dose-Response Relationship, Drug; Folic Acid; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acids; Quisqualic Acid; Retina | 1987 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Non-pharmacological effects of the use of microelectrophoresis and pressure ejection of drugs in combination.
Topics: Amino Acids; Animals; Aspartic Acid; Electrophoresis; Ibotenic Acid; Kainic Acid; Microelectrodes; N-Methylaspartate; Neurons; Nifedipine; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord | 1987 |
MK-801 powerfully protects against N-methyl aspartate neurotoxicity.
Topics: Animals; Anticonvulsants; Aspartic Acid; Autoradiography; Binding, Competitive; Chick Embryo; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Kainic Acid; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains | 1987 |
Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Convulsants; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats | 1987 |
The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Corpus Striatum; Glutamates; In Vitro Techniques; Kainic Acid; Magnesium; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Permeability; Quisqualic Acid | 1987 |
Integrated defence reaction elicited by excitatory amino acid microinjection in the midbrain periaqueductal grey region of the unrestrained cat.
Topics: Animals; Aspartic Acid; Cats; Electric Stimulation; Female; Homocysteine; Kainic Acid; Male; Microinjections; Periaqueductal Gray; Stereotyped Behavior; Vocalization, Animal | 1988 |
Long-term enhancement of K+-evoked release of L-glutamate in entorhinal kindled rats.
Topics: Animals; Aspartic Acid; Functional Laterality; Glutamates; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Potassium; Rats; Rats, Inbred Strains; Reference Values | 1988 |
2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA).
Topics: Anesthetics; Anesthetics, Dissociative; Animals; Anura; Aspartic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Medulla Oblongata; N-Methylaspartate; Neurons; Oxadiazoles; Phenylpropanolamine; Quisqualic Acid; Rats; Spinal Cord | 1986 |
The primary afferent depolarizing action of kainate in the rat.
Topics: Action Potentials; Afferent Pathways; Animals; Aspartic Acid; Capsaicin; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Oxadiazoles; Quisqualic Acid; Rats; Spinal Nerve Roots | 1986 |
The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics.
Topics: Analgesics; Anesthetics; Animals; Aspartic Acid; Chick Embryo; Hypnotics and Sedatives; Kainic Acid; N-Methylaspartate; Neurotoxins; Retina | 1986 |
Reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Cerebellar Diseases; Cerebellar Nuclei; Female; In Vitro Techniques; Kainic Acid; Male; Microscopy, Electron; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains | 1986 |
Ionic requirements for neurotoxic effects of excitatory amino acid analogues in rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium; Cerebellar Diseases; Cerebellum; Chlorides; Female; In Vitro Techniques; Kainic Acid; Male; Microscopy, Electron; N-Methylaspartate; Rats; Rats, Inbred Strains; Sodium | 1986 |
Amino acid neurotoxicity: relationship to neuronal depolarization in rat cerebellar slices.
Topics: Age Factors; Animals; Aspartic Acid; Cerebellar Diseases; Female; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Ouabain; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Veratridine | 1986 |
O-phosphohomoserine, a naturally occurring analogue of phosphonate amino acid antagonists, is an N-methyl-D-aspartate (NMDA) antagonist in rat hippocampus.
Topics: Animals; Aspartic Acid; Drug Interactions; Evoked Potentials; Hippocampus; Homoserine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1986 |
Alterations in extracellular amino acids and Ca2+ following excitotoxin administration and during status epilepticus.
Topics: Amino Acids; Animals; Aspartic Acid; Bicuculline; Calcium; Epilepsy; Ethanolamines; Extracellular Space; Glutamates; Hippocampus; Kainic Acid; N-Methylaspartate; Rabbits; Synaptic Membranes; Synaptosomes; Taurine; Tetrodotoxin | 1986 |
Long-term alterations in amino acid-induced ionic conductances in chronic epilepsy.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cobalt; Electric Conductivity; Epilepsy; Glutamates; Kainic Acid; Motor Cortex; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Sodium | 1986 |
Excitatory amino acids and epilepsy-induced changes in extracellular space size.
Topics: Animals; Aspartic Acid; Cats; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuroglia; Oxadiazoles; Potassium; Quisqualic Acid; Somatosensory Cortex; Water-Electrolyte Balance | 1986 |
Effects of kainate on CA1 hippocampal neurons recorded in vitro.
Topics: Action Potentials; Animals; Aspartic Acid; Calcium; Electric Conductivity; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium | 1986 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents.
Topics: Animals; Aspartic Acid; Electromyography; Kainic Acid; Male; Mice; Motor Activity; Muscle Spasticity; Muscle Tonus; N-Methylaspartate; Seizures; Stereoisomerism | 1987 |
DL-2-[3,4-3H]amino-4-phosphonobutyrate binding sites in the rat hippocampus: distribution and possible physiological role.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Colchicine; Hippocampus; In Vitro Techniques; Kainic Acid; Neurotoxins; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
Dopamine inhibits calcium-independent gamma-[3H]aminobutyric acid release induced by kainate and high K+ in the fish retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Dopamine; Fishes; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; N-Methylaspartate; Oxadiazoles; Picrotoxin; Potassium; Pyrrolidines; Quisqualic Acid; Retina; Serotonin | 1985 |
Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Kainic Acid; Mice; Mice, Inbred DBA; Mice, Inbred Strains; N-Methylaspartate; Oxadiazoles; Piperazines; Pyrrolidines; Quinolinic Acids; Quisqualic Acid; Seizures | 1985 |
Effect of ketamine on amino acid-evoked release of acetylcholine from rat cerebral cortex in vitro.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Ketamine; Magnesium; N-Methylaspartate; Potassium Chloride; Rats | 1985 |
Degeneration of cholinergic neurons in the basal nucleus following kainic or N-methyl-D-aspartic acid application to the cerebral cortex in the rat.
Topics: Animals; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cholinergic Fibers; Kainic Acid; N-Methylaspartate; Neural Pathways; Pyrrolidines; Rats; Rats, Inbred Strains; Substantia Innominata | 1985 |
An intracellular study of the interactions of N-methyl-DL-aspartate with ketamine in the mouse hippocampal slice.
Topics: Action Potentials; Animals; Aspartic Acid; Drug Interactions; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxadiazoles; Quisqualic Acid | 1985 |
Differences of neuronal sensitivity to amino acids and related compounds in the rat hippocampal slice.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinolinic Acids; Rats; Rats, Inbred Strains | 1985 |
Separation of the motor consequences from other actions of unilateral 6-hydroxydopamine lesions in the nigrostriatal neurones of rat brain.
Topics: Animals; Aspartic Acid; Conditioning, Operant; Corpus Striatum; Functional Laterality; Hydroxydopamines; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nerve Crush; Neural Pathways; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
The neurotoxicity of excitatory amino acids is produced by passive chloride influx.
Topics: Animals; Aspartic Acid; Calcimycin; Calcium; Cell Survival; Chlorides; Glutamates; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Potassium; Pyrrolidines; Rodentia | 1985 |
Effects of kainic acid analogues on the high affinity uptake of D-[3H] aspartate into rat cerebellar homogenates.
Topics: Animals; Aspartic Acid; Cerebellum; In Vitro Techniques; Kainic Acid; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synaptosomes; Tritium | 1986 |
Comparison of sigma- and kappa-opiate receptor ligands as excitatory amino acid antagonists.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cats; Cyclazocine; Ethylketocyclazocine; Kainic Acid; Ketamine; Ligands; Microelectrodes; N-Methylaspartate; Neurons; Oxadiazoles; Phenazocine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, sigma; Stereoisomerism | 1984 |
Electrophysiological studies on neuronal transmission in the frog's photosensory pineal organ. The effect of amino acids and biogenic amines.
Topics: 2-Aminoadipic Acid; Acetylcholine; Action Potentials; Amino Acids; Animals; Aspartic Acid; Biogenic Amines; Dose-Response Relationship, Drug; Glutamates; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Photoreceptor Cells; Pineal Gland; Rana esculenta; Serotonin; Synaptic Transmission; Taurine | 1984 |
Comparative actions of glutamate and related substances on the Xenopus laevis lateral line.
Topics: Animals; Aspartic Acid; Glutamates; Guinea Pigs; In Vitro Techniques; Kainic Acid; Neurons; Xenopus laevis | 1981 |
Pharmacological antagonists of excitant amino acid action.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Drug; Structure-Activity Relationship | 1981 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
Stimulation of rat cerebellar guanosine 3',5'-cyclic monophosphate (cyclic GMP) levels: effects of amino acid antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Protoveratrines; Rats; Rats, Inbred Strains | 1981 |
Excitatory amino acid receptors.
Topics: Animals; Aspartic Acid; Binding Sites; Brain; Glutamates; Glutamic Acid; Humans; Kainic Acid; Kinetics; Neurons; Parkinson Disease; Protein Conformation; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord | 1981 |
Specific and non-specific effects of neuro-excitatory amino acids on learning and other behaviours in the chicken.
Topics: Aggression; Aging; Animals; Aspartic Acid; Behavior, Animal; Chickens; Copulation; Glutamates; Glutamic Acid; Habituation, Psychophysiologic; Humans; Kainic Acid; Learning; N-Methylaspartate; Pattern Recognition, Visual; Pyrrolidines; Visual Perception | 1982 |
The action of six antagonists of the excitatory amino acids on neurones of the rat spinal cord.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats; Spinal Cord; Structure-Activity Relationship | 1982 |
Stimulated release of 3H-glycine from retina.
Topics: Animals; Aporphines; Aspartic Acid; Cysteic Acid; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Isoxazoles; Kainic Acid; Muscimol; Rabbits; Retina | 1982 |
Activity of the enantiomers of 2-amino-5-phosphono-valeric acid as stereospecific antagonists of excitatory aminoacids.
Topics: Adipates; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Rats; Stereoisomerism; Synaptic Transmission | 1981 |
The effect of kainic acid on excitatory synaptic activity in the rat hippocampal slice preparation.
Topics: Acetylcholine; Animals; Aspartic Acid; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Pyrrolidines; Rats; Synapses | 1981 |
Depolarization of retinal horizontal cells by excitatory amino acid neurotransmitter agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurotransmitter Agents; Retina; Structure-Activity Relationship | 1982 |
Effect of kainic acid, glutamate, and aspartate on CO2 production by goldfish tectal slices.
Topics: Animals; Aspartic Acid; Carbon Dioxide; Glutamates; Glutamic Acid; Goldfish; Kainic Acid; Ouabain; Pyrrolidines; Sodium-Potassium-Exchanging ATPase; Superior Colliculi; Time Factors | 1982 |
Effect of urethane on synaptic and amino acid-induced excitation in isolated spinal cord preparations.
Topics: Animals; Aspartic Acid; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Ranidae; Rats; Spinal Cord; Synapses; Urethane | 1982 |
Excitatory amino acid receptors and guanosine 3',5'-cyclic monophosphate in incubated slices of immature and adult rat cerebellum.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1982 |
Effects of D-alpha-aminoadipate on excitation of afferent fibers in the lateral line of Xenopus laevis.
Topics: 2-Aminoadipic Acid; Afferent Pathways; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Female; Glutamates; Glutamic Acid; Hair Cells, Auditory; Kainic Acid; Male; Mechanoreceptors; Motor Activity; N-Methylaspartate; Synaptic Transmission; Xenopus laevis | 1982 |
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system.
Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission | 1983 |
The effect of decortication on the excitatory amino acid sensitivity of striatal neurones.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Glutamates; Glutamic Acid; Kainic Acid; Neurons; Rats | 1980 |
Kainate, N-methylaspartate and other excitatory amino acids increase calcium influx into rat brain cortex cells in vitro.
Topics: Absorption; Amino Acids; Animals; Aspartic Acid; Calcium; Cerebral Cortex; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Rats | 1983 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
The role of excitatory amino acid transmitters in the mudpuppy retina: an analysis with kainic acid and N-methyl aspartate.
Topics: Animals; Aspartic Acid; Glutamates; Kainic Acid; N-Methylaspartate; Necturus; Neurons; Neurotransmitter Agents; Photoreceptor Cells; Pyrrolidines; Receptors, Cell Surface; Retina; Retinal Ganglion Cells | 1983 |
Presence of N-methyl-D-aspartate-like and kainate-like activities in bovine brain.
Topics: Animals; Aspartic Acid; Brain Chemistry; Carbon Radioisotopes; Cattle; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Pyrrolidines | 1983 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
Effects of excitatory amino acids on locomotor activity after bilateral microinjection into the rat nucleus accumbens: possible dependence on dopaminergic mechanisms.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Septal Nuclei; Synaptic Transmission | 1983 |
Effects of excitatory amino acids on dopamine synthesis in the rat retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dopamine; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Retina | 1983 |
Effects of kainic and other amino acids on synaptic excitation in rat hippocampal slices: 1. Extracellular analysis.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Evoked Potentials; Folic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Rats | 1983 |
Effects of excitatory amino acids, and of their agonists and antagonists on the release of neurotransmitters from the chick retina.
Topics: Amino Acids; Animals; Aspartic Acid; Chickens; Cysteic Acid; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Endings; Neurotransmitter Agents; Receptors, Neurotransmitter; Retina; Synapses; Synaptic Transmission | 1983 |
Differential sensitivity of selected brain areas to excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Rats; Sodium; Stimulation, Chemical | 1983 |
Transmitter interactions in the rabbit retina.
Topics: Acetylcholine; Animals; Aspartic Acid; Atropine; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Retina | 1983 |
On the sensitivity of H1 horizontal cells of the carp retina to glutamate, aspartate and their agonists.
Topics: Animals; Aspartic Acid; Carps; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Retina | 1984 |
Localization of L-glutamate and L-aspartate synaptic receptors in chick retinal neurons.
Topics: Animals; Aspartic Acid; Chickens; Glutamates; Glutamic Acid; Kainic Acid; Male; Neurons; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter; Retina | 1984 |
Responses of solitary retinal horizontal cells to L-glutamate and kainic acid are antagonized by D-aspartate.
Topics: Animals; Aspartic Acid; Cyprinidae; Excitatory Amino Acid Antagonists; Folic Acid; Glutamates; Glutamic Acid; Goldfish; Interneurons; Kainic Acid; Pyrrolidines; Retina; Stereoisomerism | 1984 |
The halomethylketone derivative L-Glu-gamma-DL-Ala-CH2Cl and N-methyl-D-aspartate as selective antagonists against L-glutamate and kainate excitation respectively on Retzius cells of the leech, Hirudo medicinalis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Ganglia; Kainic Acid; Leeches; Membrane Potentials; N-Methylaspartate; Pyrrolidines; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1984 |
Changes in regional neurotransmitter amino acid levels in rat brain during seizures induced by L-allylglycine, bicuculline, and kainic acid.
Topics: Allylglycine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Male; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Taurine | 1984 |
Effects of glutamic acid, kainic acid and aspartic acid on GABA release from rat retina degenerated by kainic acid.
Topics: Animals; Aspartic Acid; Depression, Chemical; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; Pyrrolidines; Rats; Retina; Retinal Degeneration; Stimulation, Chemical | 1984 |
Effect of kainic acid on the release of exogenous neurotransmitters from synaptosome preparations.
Topics: Animals; Aspartic Acid; gamma-Aminobutyric Acid; Goldfish; Hippocampus; Kainic Acid; Kinetics; Mitochondria; Neurotransmitter Agents; Potassium; Pyrrolidines; Rats; Synaptosomes | 1984 |
The effect of the dioxolanes on amino acid induced excitation in the mammalian spinal cord.
Topics: Animals; Aspartic Acid; Cats; Dioxolanes; Dioxoles; Kainic Acid; Ketamine; N-Methylaspartate; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Species Specificity; Spinal Cord; Stereoisomerism; Structure-Activity Relationship | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
Studies of effects of kainic acid lesions in the dorsal lateral geniculate nucleus of rat.
Topics: Animals; Aspartic Acid; Autoradiography; Axonal Transport; Evoked Potentials, Visual; Female; Geniculate Bodies; Kainic Acid; Microscopy, Fluorescence; Nerve Degeneration; Nerve Fibers; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission; Visual Cortex; Visual Pathways | 1982 |
Intracellularly-recorded effects of glutamate and aspartate on neurones in the guinea-pig olfactory cortex slice.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Female; gamma-Aminobutyric Acid; Glutamates; Guinea Pigs; Kainic Acid; Male; Neurons; Olfactory Bulb; Olfactory Pathways; Synapses; Synaptic Transmission | 1980 |
Action of glutamate and aspartate analogues on rod horizontal and bipolar cells.
Topics: Aminobutyrates; Animals; Aspartic Acid; Dogfish; Glutamates; Kainic Acid; Light; Membrane Potentials; Organophosphorus Compounds; Photoreceptor Cells; Synaptic Transmission; Vision, Ocular | 1981 |
Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Pyrrolidines; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1982 |
Differentiation of excitatory amino acid receptors in the rat caudal trigeminal nucleus: a microiontophoretic study.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Glutamates; Kainic Acid; Male; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Trigeminal Nuclei | 1982 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
Chemical characteristics of the L-glutamate receptor on the Onchidium neuron.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Esophagus; Excitatory Amino Acid Antagonists; Glutamates; Glutamine; Helix, Snails; Kainic Acid; Membrane Potentials; Mollusca; Neurons; Potassium; Receptors, Cell Surface; Receptors, Glutamate | 1983 |
Quisqualic acid excitation of cortical neurones is selectively antagonized by streptomycin.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Kainic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Streptomycin; Synaptic Transmission | 1983 |
Characterization of [L-3H]aspartate binding to chick retinal subcellular fractions.
Topics: Animals; Aspartic Acid; Binding Sites; Cell Membrane; Chickens; Glutamates; Intracellular Membranes; Kainic Acid; Receptors, Neurotransmitter; Retina; Sodium; Subcellular Fractions | 1982 |
Effects of a spider toxin on the glutaminergic synapse of lobster muscle.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Kainic Acid; Membrane Potentials; Nephropidae; Neuromuscular Junction; Neurotoxins; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter; Spider Venoms; Time Factors | 1983 |
Excitatory amino acid receptors in Xenopus embryo spinal cord and their role in the activation of swimming.
Topics: Animals; Aspartic Acid; Kainic Acid; Manganese; Membrane Potentials; Motor Activity; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Swimming; Xenopus | 1984 |
Stimulation of GABA release from retinal horizontal cells by potassium and acidic amino acid agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Goldfish; In Vitro Techniques; Kainic Acid; Oxadiazoles; Potassium; Quisqualic Acid; Retina | 1983 |
Antagonism of the hypermotility response induced by excitatory amino acids in the rat nucleus accumbens.
Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Aspartic Acid; Diaminopimelic Acid; Glutamates; Injections; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Septal Nuclei | 1984 |
Magnesium selectively inhibits N-methyl-aspartic acid-induced hypermotility after intra-accumbens injection.
Topics: Animals; Aspartic Acid; Calcium Chloride; Injections; Kainic Acid; Magnesium; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1984 |
Differential sensitivity of rat cerebellar cells in vitro to the neurotoxic effects of excitatory amino acid analogues.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; In Vitro Techniques; Interneurons; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats | 1984 |
The release of gamma-aminobutyric acid from horizontal cells of the goldfish (Carassius auratus) retina.
Topics: Animals; Aspartic Acid; Calcium; Cell Separation; Cobalt; Cyprinidae; Darkness; gamma-Aminobutyric Acid; Glutamates; Goldfish; In Vitro Techniques; Interneurons; Kainic Acid; Oxadiazoles; Potassium; Quisqualic Acid; Retina; Sodium; Time Factors | 1984 |
The dissociation of evoked release of [3H]-GABA and of endogenous GABA from chick retina in vitro.
Topics: Animals; Aspartic Acid; Chickens; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Perfusion; Potassium Chloride; Retina; Tritium | 1984 |
Structure-activity relations of dipeptide antagonists of excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Dipeptides; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Structure-Activity Relationship | 1984 |
N-acetyl-aspartyl-glutamate: regional levels in rat brain and the effects of brain lesions as determined by a new HPLC method.
Topics: Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Hippocampus; Kainic Acid; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1984 |
Kainic acid evoked release of D-[3H]aspartate from rat striatum in vitro: characterization and pharmacological modulation.
Topics: Animals; Aspartic Acid; Bromocriptine; Calcium; Corpus Striatum; Female; In Vitro Techniques; Kainic Acid; Potassium; Pyrrolidines; Rats; Rats, Inbred Strains; Sodium; Tritium | 1984 |
Actions of acidic amino acids on the excitability of medial hypothalamic neurons in the rat.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Homocysteine; Hypothalamus; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; Neurons; Rats; Rats, Inbred Strains | 1983 |
Evoked release of aspartate and glutamate: disparities between prelabeling and direct measurement.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Glutamates; Hippocampus; Kainic Acid; Male; Methods; Potassium; Rats; Rats, Inbred Strains; Tritium | 1983 |
Solitary horizontal cells in culture--II. A new tool for examining effects of photoreceptor neurotransmitter candidates.
Topics: 2-Aminoadipic Acid; Action Potentials; Animals; Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Glutamates; Goldfish; Kainic Acid; Membrane Potentials; Neurons; Retina | 1983 |
Effects of kainic acid in rat brain synaptosomes: the involvement of calcium.
Topics: Animals; Aspartic Acid; Brain; Calcium; Cerebral Cortex; Kainic Acid; Kinetics; Male; Membrane Potentials; Mesencephalon; Pyrrolidines; Rats; Rats, Inbred Strains; Synaptosomes | 1984 |
Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats | 1982 |
Acute motor effects of N-methyl-D-aspartic acid and kainic acid applied focally to mesencephalic dopamine cell body regions in the rat.
Topics: Animals; Aspartic Acid; Dopamine; Female; Fluphenazine; Kainic Acid; Mesencephalon; Motor Activity; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Substantia Nigra | 1980 |
Kainate-enhanced release of D-[3H]aspartate from cerebral cortex and striatum: reversal by baclofen and pentobarbital.
Topics: Animals; Aspartic Acid; Baclofen; Biological Transport; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Guinea Pigs; Kainic Acid; Kinetics; Phenobarbital; Pyrrolidines; Sodium; Tritium | 1983 |
Evidence supporting the indirect depolarization of primary afferent terminals in the frog by excitatory amino acids.
Topics: Amino Acids; Animals; Anura; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; Motor Neurons; Nerve Endings; Neurons, Afferent; Rana pipiens; Rana temporaria; Spinal Nerve Roots | 1980 |
Behavioural and biochemical studies in rats with N-methyl-D-aspartic acid and kainic acid [proceedings].
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Chemistry; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats | 1980 |
Antagonism of excitatory amino acid-induced and synaptic excitation of spinal neurones by cis-2,3-piperidine dicarboxylate.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rana temporaria; Rats; Spinal Cord; Synapses | 1981 |
Two conductance mechanisms activated by applications of L-glutamic, L-aspartic, DL-homocysteic, N-methyl-D-aspartic, and DL-kainic acids to cultured mammalian central neurones.
Topics: Animals; Aspartic Acid; Cells, Cultured; Central Nervous System; Female; Glutamates; Homocysteine; In Vitro Techniques; Kainic Acid; Magnesium; Mice; N-Methylaspartate; Neural Conduction; Neurons | 1980 |
N-Methyl-D-aspartate acid: a convulsant with weak neurotoxic properties.
Topics: Animals; Aspartic Acid; Convulsants; Corpus Striatum; Hippocampus; Kainic Acid; N-Methylaspartate; Neurotoxins; Rats | 1981 |
An evaluation of gamma-glutamyl dipeptide derivatives as antagonists of amino acid-induced Na+ fluxes in rat striatum slices.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dipeptides; Glutamine; Kainic Acid; N-Methylaspartate; Rats; Sodium | 1982 |
Methyltetrahydrofolate as an antagonist of excitatory amino acids on spinal neurones.
Topics: Amino Acids; Animals; Aspartic Acid; Folic Acid; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrahydrofolates | 1982 |
Specific high-affinity binding of L-[3H]aspartate to rat brain membranes.
Topics: Animals; Aspartic Acid; Binding Sites; Brain; Cations, Divalent; Cell Membrane; Kainic Acid; Male; Rats; Rats, Inbred Strains; Sodium; Time Factors | 1982 |
Effects of glutamic acid diethylester and kainic acid diethylester on discharges of Renshaw cells.
Topics: Acetylcholine; Action Potentials; Animals; Aspartic Acid; Cats; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Pyrrolidines; Spinal Cord | 1981 |
Effect of kainate on ATP levels and glutamate metabolism in cerebellar slices.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Glutamates; Glutamine; In Vitro Techniques; Kainic Acid; Male; Pyrrolidines; Rats; Time Factors | 1980 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine Maleate; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Ion Channels; Kainic Acid; Kinetics; Magnesium Chloride; N-Methylaspartate; Neurotoxins; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Signal Transduction; Tumor Cells, Cultured | 1994 |
Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino-4-propyl-5-phosphono-3-pentenoate (CGP 39653), [3H]6-cya
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Kainic Acid; Neurotransmitter Uptake Inhibitors; Prosencephalon; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1995 |
Intracellular acidification and Ca2+ transients in cultured rat cerebellar astrocytes evoked by glutamate agonists and noradrenaline.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Cycloleucine; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Fura-2; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Neurotoxins; Norepinephrine; Rats; Receptors, Metabotropic Glutamate | 1995 |
Cone photoreceptors respond to their own glutamate release in the tiger salamander.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Chloride Channels; Exocytosis; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission; Time Factors | 1995 |
Effect of domoic acid on brain amino acid levels.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Kainic Acid; Neuromuscular Depolarizing Agents; Rats | 1995 |
Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats.
Topics: Anesthesia; Animals; Aspartic Acid; Bicuculline; Cardiovascular System; Excitatory Amino Acids; Hypothalamus; Kainic Acid; Male; Microinjections; Rats; Rats, Sprague-Dawley | 1995 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Modulation of calcium-dependent and -independent components of veratridine-evoked release of glutamate from rat cerebellum.
Topics: Amiloride; Animals; Apamin; Aspartic Acid; Calcium; Calcium Channel Blockers; Cerebellum; Cobalt; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; omega-Conotoxins; Peptides; Perfusion; Rats; Rats, Wistar; Ruthenium Red; Tetrodotoxin; Verapamil; Veratridine | 1993 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Comparison of the superfused efflux of preaccumulated D-[3H]aspartate and endogenous L-aspartate and L-glutamate from rat cerebrocortical minislices.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tetrodotoxin | 1994 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Amino acid neurotransmitters in nucleus tractus solitarius: an in vivo microdialysis study.
Topics: Afferent Pathways; Amino Acids; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Electric Stimulation; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Male; Membrane Potentials; Microdialysis; Nerve Endings; Neurotransmitter Agents; Nodose Ganglion; Potassium; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors; Vagus Nerve | 1993 |
Depolarization elicits, while hyperpolarization blocks uptake of endogenous glutamate by retinal horizontal cells of the turtle.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Calcium; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Kainic Acid; Neurotransmitter Uptake Inhibitors; Photoreceptor Cells; Pipecolic Acids; Retina; Turtles | 1993 |
Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia.
Topics: Amino Acids; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Cerebral Cortex; Corpus Striatum; Dialysis; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Kainic Acid; Male; Neurotoxins; Prosencephalon; Rats; Rats, Wistar; Receptors, Neurotransmitter | 1994 |
Heterocarrier-mediated reciprocal modulation of glutamate and glycine release in rat cerebral cortex and spinal cord synaptosomes.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium; Spinal Cord; Synaptosomes | 1994 |
Interactions of gamma-L-glutamyltaurine with excitatory aminoacidergic neurotransmission.
Topics: Aging; Animals; Aspartic Acid; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclic GMP; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Mice; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synaptic Transmission; Synaptosomes; Taurine | 1994 |
The effect of L-glutamate on the afferent resting activity in the cephalopod statocyst.
Topics: Action Potentials; Afferent Pathways; Animals; Aspartic Acid; Decapodiformes; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mollusca; N-Methylaspartate; Nerve Fibers; Octopodiformes; Postural Balance; Quisqualic Acid; Species Specificity | 1994 |
Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus.
Topics: Adrenalectomy; Animals; Aspartic Acid; Corticosterone; Delayed-Action Preparations; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Taurine | 1994 |
A subtype of the metabotropic glutamate receptor family in the olfactory system of Atlantic salmon.
Topics: Animals; Aspartic Acid; Blotting, Northern; Brain; Cell Membrane; DNA Probes; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kainic Acid; N-Methylaspartate; Nucleic Acid Hybridization; Olfactory Mucosa; Rats; Receptors, Metabotropic Glutamate; Salmon; Taurocholic Acid; Type C Phospholipases | 1994 |
Pre- and post-synaptic modulators of excitatory neurotransmission: comparative effects on hypoxia/hypoglycemia in cortical cultures.
Topics: Animals; Aspartic Acid; Benzopyrans; Calcium Channel Blockers; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cromakalim; Diazoxide; Embryo, Mammalian; Glutamates; Hypoglycemia; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Neurons; Potassium Channels; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 1994 |
N-acetylaspartylglutamate selectively inhibits neuronal responses to N-methyl-D-aspartic acid in vitro.
Topics: Animals; Aspartic Acid; Canavan Disease; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Dipeptides; Kainic Acid; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neurons | 1994 |
Regulation of D-aspartate release by glutamate and GABA receptors in cerebral cortical slices from developing and ageing mice.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Quisqualic Acid; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Taurine | 1994 |
N-acetylaspartate as an in vivo marker of neuronal viability in kainate-induced status epilepticus: 1H magnetic resonance spectroscopic imaging.
Topics: Animals; Aspartic Acid; Biomarkers; Cell Survival; Kainic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Protons; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1994 |
The release of glutamate and aspartate from rat brain synaptosomes in response to domoic acid (amnesic shellfish toxin) and kainic acid.
Topics: Animals; Aspartic Acid; Brain; Glutamic Acid; Kainic Acid; Male; Marine Toxins; Neurotoxins; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis.
Topics: Amino Acids; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Basal Ganglia; Calcium; Cerebral Cortex; Dicarboxylic Acids; Glutamic Acid; Halothane; Kainic Acid; Male; Membrane Potentials; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Potassium; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spider Venoms; Substantia Nigra; Tetrodotoxin; Urethane | 1996 |
Extracellular striatal dopamine and glutamate after decortication and kainate receptor stimulation, as measured by microdialysis.
Topics: Animals; Aspartic Acid; Cerebral Decortication; Dopamine; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neostriatum; Rats; Rats, Wistar; Receptors, Kainic Acid | 1996 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Mechanisms of H+ and Na+ changes induced by glutamate, kainate, and D-aspartate in rat hippocampal astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bicarbonates; Buffers; Carbon Dioxide; Glutamic Acid; Hippocampus; Hydrogen; Kainic Acid; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride | 1996 |
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Differences in the release of L-glutamate and D-aspartate from primary neuronal chick cultures.
Topics: Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Chick Embryo; Drug Evaluation, Preclinical; Exocytosis; Glutamates; Glutamic Acid; Kainic Acid; Neurons | 1996 |
Autoradiographic studies indicate regional variations in the characteristics of L-glutamate transporters in the rat brain.
Topics: Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Binding Sites; Biological Transport; Brain Chemistry; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Male; Neostriatum; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
MR spectroscopic imaging and diffusion-weighted MRI for early detection of kainate-induced status epilepticus in the rat.
Topics: Animals; Aspartic Acid; Blood Gas Analysis; Brain; Excitatory Amino Acid Agonists; Hydrogen-Ion Concentration; Kainic Acid; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Status Epilepticus | 1996 |
Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D-[3H] aspartic acid in cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin; Tritium | 1996 |
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Protons; Rats; Rats, Sprague-Dawley; Seizures; Temporal Lobe | 1997 |
Metabolic and pathological effects of temporal lobe epilepsy in rat brain detected by proton spectroscopy and imaging.
Topics: Animals; Aspartic Acid; Behavior, Animal; Choline; Creatine; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Kainic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Temporal Lobe; Time Factors | 1997 |
Intracellular acidification of the leech giant glial cell evoked by glutamate and aspartate.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Invertebrate; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Leeches; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Sodium | 1997 |
Evidence for increased cellular uptake of glutamate and aspartate in the rat hippocampus during kainic acid seizures. A microdialysis study using the "indicator diffusion' method.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Glutamic Acid; Hippocampus; Kainic Acid; Male; Microdialysis; Rats; Rats, Wistar; Seizures | 1997 |
Glutamate receptor agonists evoked Ca(2+)-dependent and Ca(2+)-independent release of [3H]D-aspartate from cultured chick retina cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Chickens; Excitatory Amino Acid Agonists; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Potassium Chloride; Receptors, Glutamate; Retina; Tritium | 1996 |
Characterization of glutamate transporter function in the tiger salamander retina.
Topics: Ambystoma; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Biological Transport; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; Microscopy, Electron; Photic Stimulation; Retina; Time Factors | 1997 |
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 1997 |
Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Antipsychotic Agents; Aspartic Acid; Autoradiography; Basal Ganglia; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; Kainic Acid; Male; Middle Aged; Neostriatum; Receptors, AMPA; Receptors, Glutamate; Schizophrenia; Suicide | 1997 |
Postsynaptic response kinetics are controlled by a glutamate transporter at cone photoreceptors.
Topics: Ambystoma; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Darkness; Glutamic Acid; Kainic Acid; Kinetics; Light; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Retina; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission | 1998 |
Kainate potentiates D-aspartate release from hippocampal slices from developing and ageing mice.
Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Excitatory Amino Acid Agonists; Female; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; Stimulation, Chemical | 1997 |
Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Glutamic Acid; Hippocampus; Kainic Acid; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Rats; Rats, Wistar; Receptors, Glutamate; Spider Venoms; Synaptosomes | 1998 |
Aspartate as a selective NMDA receptor agonist in cultured cells from the avian retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Retina | 1998 |
Modulation of human glutamate transporter activity by phorbol ester.
Topics: Amino Acid Transport System X-AG; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamates; Glutamic Acid; Humans; Kainic Acid; Kinetics; Phorbol Esters; Protein Kinase C; Retinoblastoma; Staurosporine; Tumor Cells, Cultured | 1998 |
MRS metabolic markers of seizures and seizure-induced neuronal damage.
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Cell Count; Choline; Creatine; Cycloheximide; Hippocampus; Kainic Acid; Lactates; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1998 |
Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue.
Topics: Amino Acid Transport System X-AG; Amino Acids; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Conserved Sequence; Cysteine; Ethylmaleimide; HeLa Cells; Humans; Kainic Acid; Mesylates; Mutagenesis, Site-Directed; Potassium; Protein Conformation; Sodium; Sulfhydryl Reagents | 1998 |
Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Gene Expression; Glutamates; Glutamic Acid; Humans; Kainic Acid; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Alignment; Serine; Xenopus laevis | 1998 |
Action of excitatory amino acids on hypodermis and the motornervous system of Ascaris suum: pharmacological evidence for a glutamate transporter.
Topics: Amino Acid Transport System X-AG; Animals; Ascaris suum; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport, Active; Calcium; Dose-Response Relationship, Drug; Electric Conductivity; Epithelium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Microelectrodes; Motor Neurons; Quinoxalines; Sodium | 1998 |
[31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Cerebral Cortex; Cerebrospinal Fluid; Energy Metabolism; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Kainic Acid; Lactates; Magnesium; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Phosphorus Isotopes; Protons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 1998 |
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin | 1998 |
The release of amino acids from rat neostriatum and substantia nigra in vivo: a dual microdialysis probe analysis.
Topics: Animals; Aspartic Acid; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neostriatum; Rats; Rats, Wistar; Substantia Nigra; Taurine | 1998 |
Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Blood Flow Velocity; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Therapy, Combination; Glutamic Acid; Ion Pumps; Kainic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Stilbenes | 1999 |
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Glutamic Acid; Glycine; HeLa Cells; Humans; Kainic Acid; Kinetics; Mutagenesis, Site-Directed; Neurotransmitter Agents; Recombinant Proteins; Serine; Sodium | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Changes in expression of neuronal and glial glutamate transporters in rat hippocampus following kainate-induced seizure activity.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Brain; Brain Chemistry; Carrier Proteins; Cell Death; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation, Developmental; Glutamate Plasma Membrane Transport Proteins; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Neuroglia; Neuronal Plasticity; Neurons; Oligonucleotide Probes; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; RNA, Messenger; Symporters; Tritium | 1999 |
The effects of excitatory amino acids on isolated gut segments of the rat.
Topics: Animals; Aspartic Acid; Cycloleucine; Digestive System; Digestive System Physiological Phenomena; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Female; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; N-Methylaspartate; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.
Topics: Animals; Aspartic Acid; Astrocytes; bcl-2-Associated X Protein; Cell Death; Cell Division; Cell Nucleus; Cell Size; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Female; Genotype; Kainic Acid; Male; Mice; Motor Neurons; Nerve Degeneration; Paraquat; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Spinal Cord; Superoxides | 1999 |
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Topics: Acute Disease; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloidosis; Animals; Apoptosis; Aspartic Acid; Aspartic Acid Endopeptidases; Brain Diseases; Camptothecin; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Excitatory Amino Acid Agonists; Hippocampus; Humans; In Situ Nick-End Labeling; Kainic Acid; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oligopeptides; Rabbits; Rats; Rats, Wistar; Sweden; Tumor Cells, Cultured | 1999 |
Nontransportable inhibitors attenuate reversal of glutamate uptake in synaptosomes following a metabolic insult.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Pyrrolidines; Rats; Synaptosomes; Tritium | 1999 |
Differential effects of haloperidol and clozapine on ionotropic glutamate receptors in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Aspartic Acid; Binding Sites; Brain; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1999 |
The ontogeny of glutamate receptors and D-aspartate binding sites in the ovine CNS.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Embryonic and Fetal Development; Fetus; Glutamic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Sheep | 1999 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
SNARE protein-dependent glutamate release from astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Bacterial Agents; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Botulinum Toxins; Botulinum Toxins, Type A; Calcium; Cells, Cultured; Coculture Techniques; Dicarboxylic Acids; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Kainic Acid; Macrolides; Membrane Potentials; Membrane Proteins; Nerve Tissue Proteins; Neurons; Proton-Translocating ATPases; Pyrrolidines; Rats; SNARE Proteins; Vesicular Transport Proteins | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 2000 |
The evaluation of the potential of botulinum C3 enzyme as an exogenous differentiation inducing factor to neurons.
Topics: Acetylcholine; ADP Ribose Transferases; Aniline Compounds; Animals; Antibodies, Monoclonal; Aspartic Acid; Botulinum Toxins; Calcium; Cell Differentiation; Excitatory Amino Acid Agonists; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Immunohistochemistry; Kainic Acid; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Muscarine; Muscarinic Agonists; Neurons; Potassium; Xanthenes | 2000 |
Transient increase in the high affinity [3H]-L-glutamate uptake activity during in vitro development of hippocampal neurons in culture.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Dicarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Kainic Acid; Neuroglia; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Symporters; Time Factors; Tritium | 2001 |
Characterization of transient focal ischemia-induced increases in extracellular glutamate and aspartate in spontaneously hypertensive rats.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Extracellular Space; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Rats; Rats, Inbred SHR; Reperfusion Injury; Tetrodotoxin; Time Factors | 2000 |
Effects of glial glutamate transporter inhibitors on intracellular Na+ in mouse astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzofurans; Binding, Competitive; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Intracellular Fluid; Kainic Acid; Mice; Neurotransmitter Uptake Inhibitors; Protein Isoforms; Pyrrolidines; Sodium; Stereoisomerism | 2001 |
Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electroencephalography; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Homovanillic Acid; Kainic Acid; Neurochemistry; Receptors, Dopamine D1; Receptors, Dopamine D2; Seizures; Sulpiride | 2001 |
Intrathecal magnesium sulfate attenuates algogenic behavior and spinal amino acids release after kainic acid receptor activation in rats.
Topics: Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Calcium Channel Blockers; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Kainic Acid; Magnesium Sulfate; Male; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Taurine | 2001 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission; Temperature; Thalamus | 2001 |
GABA release induced by aspartate-mediated activation of NMDA receptors is modulated by dopamine in a selective subpopulation of amacrine cells.
Topics: Amacrine Cells; Animals; Aspartic Acid; Carrier Proteins; Cell Survival; Chickens; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Isoenzymes; Kainic Acid; L-Lactate Dehydrogenase; Membrane Proteins; Membrane Transport Proteins; N-Methylaspartate; Organic Anion Transporters; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2001 |
Differing effects of substrate and non-substrate transport inhibitors on glutamate uptake reversal.
Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cells, Cultured; Dicarboxylic Acids; Glutamic Acid; Kainic Acid; Mice; Nerve Tissue Proteins; Neurons; Prosencephalon; Pyrrolidines; Substrate Specificity | 2001 |
Effects of metabotropic glutamate receptor agonists and antagonists on D-aspartate release from mouse cerebral cortical and striatal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Metabotropic Glutamate; Tritium | 2001 |
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Binding, Competitive; Biological Transport; Cells, Cultured; Cerebral Cortex; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Kainic Acid; Mice; Neurons; Sodium; Symporters | 2003 |
The effect of 6-hydroxydopamine lesions on the release of amino acids in the direct and indirect pathways of the basal ganglia: a dual microdialysis probe analysis.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Microdialysis; Models, Animal; Oxidopamine; Parkinson Disease; Potassium; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 2003 |
Local differences in GABA release induced by excitatory amino acids during retina development: selective activation of NMDA receptors by aspartate in the inner retina.
Topics: Animals; Aspartic Acid; Carrier Proteins; Chick Embryo; Excitatory Amino Acids; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Kainic Acid; Membrane Proteins; Membrane Transport Proteins; N-Methylaspartate; Organic Anion Transporters; Receptors, N-Methyl-D-Aspartate; Retina; Zygote | 2003 |
Identification of glutamate transporters and receptors in mouse testis.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Brain; Cells, Cultured; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; GluK2 Kainate Receptor; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Symporters; Synaptosomes; Testis | 2004 |
Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra.
Topics: Amino Acid Transport System X-AG; Animals; Anion Transport Proteins; Aspartic Acid; Astrocytes; Brain Ischemia; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Microdialysis; Neurons; Rats; Receptors, Glutamate; Tamoxifen; Taurine | 2004 |
Extracellular taurine in the substantia nigra: taurine-glutamate interaction.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Chemistry; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Ketamine; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Substantia Nigra; Taurine; Time Factors; Zinc | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Retinal bipolar cell input mechanisms in giant danio. II. Patch-clamp analysis of on bipolar cells.
Topics: Aminobutyrates; Animals; Aspartic Acid; Barium; D-Aspartic Acid; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; In Vitro Techniques; Isoquinolines; Kainic Acid; Light; Membrane Potentials; Neurons; Patch-Clamp Techniques; Photic Stimulation; Potassium Channel Blockers; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Tetraethylammonium; Time Factors; Visual Pathways; Zebrafish | 2005 |
NMDA-receptor mediated efflux of N-acetylaspartate: physiological and/or pathological importance?
Topics: Amino Acids; Animals; Aspartic Acid; Cell Death; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Glutathione; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Potassium; Propidium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrophotometry, Ultraviolet | 2004 |
[Changes of amino acid content in hippocampus of epileptic rats treated with volatile oil of Acorus tatarinowii].
Topics: Acorus; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Male; Oils, Volatile; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 2004 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes | 2004 |
Changes in intracellular cyclic AMP formation mask opposing modulation of kainate-enhanced glutamate release in the striatum.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Alloxan; Animals; Aspartic Acid; Cyclic AMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Isoproterenol; Kainic Acid; Kinetics; Mice; Neostriatum; Phenethylamines | 2004 |
Retinal bipolar cell input mechanisms in giant danio. III. ON-OFF bipolar cells and their color-opponent mechanisms.
Topics: Animals; Aspartic Acid; Color; D-Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Photic Stimulation; Propionates; Quinoxalines; Retina; Visual Pathways; Zebrafish | 2005 |
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH.
Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Ammonia; Animals; Aspartic Acid; Astrocytes; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Fluoresceins; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Methylamines; Mice; Microscopy, Fluorescence; Spectrometry, Fluorescence; Thapsigargin; Ultraviolet Rays | 2005 |
Over-expression of the human EAAT2 glutamate transporter within neurons of mouse organotypic hippocampal slice cultures leads to increased vulnerability of CA1 pyramidal cells.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Blotting, Western; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Kainic Acid; Mice; Neuroglia; Organ Culture Techniques; Phosphopyruvate Hydratase; Pyramidal Cells; Symporters; Time Factors; Transduction, Genetic; Tritium | 2005 |
Developmental changes in AMPA and kainate receptor-mediated quantal transmission at thalamocortical synapses in the barrel cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebral Cortex; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Mice; Models, Neurological; Monte Carlo Method; Neural Conduction; Neural Pathways; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Kainic Acid; Strontium; Synapses; Synaptic Transmission; Thalamus; Time Factors | 2005 |
Inhibition of glutamate transporters increases the minimum alveolar concentration for isoflurane in rats.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Blood Pressure; Injections, Spinal; Isoflurane; Kainic Acid; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Differential effect of glutamate transporter inhibition on EPSCs in the morphine naïve and morphine tolerant neonatal spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Morphine; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Taurine, taurine analogues, and taurine functions: overview.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Male; Microdialysis; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Taurine; Tetrodotoxin | 2006 |
Inhibition of glutamate transporters results in a "suppression-burst" pattern and partial seizures in the newborn rat.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsies, Partial; Functional Laterality; Injections, Intraventricular; Kainic Acid; Male; Pilocarpine; Rats; Rats, Wistar; Receptors, Glutamate; Videotape Recording | 2007 |
Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Cerebellum; Cytoplasm; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glucosamine; Glutamic Acid; Kainic Acid; Lithium; Membrane Potentials; Mice; Mice, Inbred Strains; Models, Biological; Nerve Fibers; Neuroglia; Sodium; Sodium-Calcium Exchanger | 2007 |
Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by 'pathologically' elevated extraterminal K+ concentrations.
Topics: Animals; Aspartic Acid; Calcium Channels; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Exocytosis; Extracellular Fluid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperkalemia; Kainic Acid; Macrolides; Male; Potassium; Presynaptic Terminals; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptosomes | 2007 |
Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2.
Topics: Amino Acid Substitution; Aspartic Acid; Cadmium; Chelating Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; HeLa Cells; Humans; Kainic Acid; Mutation, Missense; Phenanthrolines; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity | 2008 |
Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Malformations of Cortical Development; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2008 |
Effect of safranal on extracellular hippocampal levels of glutamate and aspartate during kainic Acid treatment in anesthetized rats.
Topics: Anesthesia; Animals; Aspartic Acid; Cyclohexenes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Rats; Rats, Wistar; Terpenes | 2008 |
Differential effects of glutamate transporter inhibitors on the global electrophysiological response of astrocytes to neuronal stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Kainic Acid; Neurons; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley | 2008 |
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cesium; Chlorides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; In Vitro Techniques; Kainic Acid; Macrolides; Magnesium; Male; Melatonin; Membrane Potentials; Pineal Gland; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2008 |
Regulation of glutamate transport in developing rat oligodendrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Fibroblast Growth Factors; GABA Antagonists; Gangliosides; Gene Expression Regulation, Developmental; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurons; O Antigens; Oligodendroglia; Patch-Clamp Techniques; Platelet-Derived Growth Factor; Pregnancy; Quinoxalines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Tritium | 2009 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Kainic Acid; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Size; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors | 2009 |
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic Acid; Muscle Relaxation; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2009 |
Inhibition of presynaptic release-facilitatory kainate autoreceptors by extracellular cyclic GMP.
Topics: Animals; Aspartic Acid; Autoreceptors; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synaptosomes | 2010 |
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Magnesium Deficiency; Male; Neurons; Neurotransmitter Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Region- and pattern-specific effects of glutamate uptake blockers on epileptiform activity in rat brain slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neurons; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Inflammation; Kainic Acid; Male; Nicotinic Acids; Pain; Phosphoserine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2011 |
Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Aspartic Acid; Ceftriaxone; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Genotype; Huntington Disease; Kainic Acid; Male; Mice; Mice, Transgenic; Microinjections; Transcription, Genetic; Up-Regulation | 2012 |
Glial glutamate transporter and glutamine synthetase regulate GABAergic synaptic strength in the spinal dorsal horn.
Topics: Animals; Aspartic Acid; Astrocytes; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamine; Kainic Acid; Male; Neuroglia; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Synapses | 2012 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
Intermittent hypobaric hypoxia induces neuroprotection in kainate-induced oxidative stress in rats.
Topics: Animals; Apoptosis; Aspartic Acid; Caspase 3; Erythropoietin; Hypoxia, Brain; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Neurons; NF-kappa B; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior.
Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Blotting, Western; Ceftriaxone; Cocaine-Related Disorders; Conditioning, Operant; Cues; Excitatory Amino Acid Transporter 2; Feeding Behavior; Kainic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Substance Withdrawal Syndrome | 2013 |
EAAT and Xc⁻ Exchanger Inhibition Depletes Glutathione in the Transformed Human Lens Epithelial Cell Line SRA 01/04.
Topics: Amino Acid Transport System y+; Aspartic Acid; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Epithelial Cells; Excitatory Amino Acid Antagonists; Glutamate Plasma Membrane Transport Proteins; Glutathione; Humans; Kainic Acid; Lens, Crystalline | 2016 |
Metabolic changes in early poststatus epilepticus measured by MR spectroscopy in rats.
Topics: Animals; Antigens, Nuclear; Aspartic Acid; Brain Chemistry; Creatine; Epilepsy, Temporal Lobe; Glutamine; Inositol; Kainic Acid; Macrophage Activation; Magnetic Resonance Spectroscopy; Male; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse.
Topics: Animals; Aspartic Acid; Astrocytes; Benzodiazepines; Biogenic Polyamines; Calcium; Cerebral Cortex; Enzyme Induction; Genetic Predisposition to Disease; Gliosis; Hippocampus; Kainic Acid; Male; Metallothionein; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Receptors, AMPA; Recombinant Fusion Proteins; Seizures; Synaptosomes; Up-Regulation | 2016 |
Metabolic injury in a variable rat model of post-status epilepticus.
Topics: Animals; Aspartic Acid; Cluster Analysis; Creatine; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Diseases; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2016 |
Ceftriaxone-mediated upregulation of the glutamate transporter GLT-1 contrasts neurotoxicity evoked by kainate in rat organotypic spinal cord cultures.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Astrocytes; Ceftriaxone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Motor Neurons; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats, Wistar; Spinal Cord; Up-Regulation | 2017 |
Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM.
Topics: Aspartic Acid; Cryoelectron Microscopy; GluK3 Kainate Receptor; HEK293 Cells; Humans; Kainic Acid; Ligands; Models, Molecular; Neurotransmitter Agents; Protein Domains; Protein Multimerization; Receptors, Kainic Acid | 2020 |