aspartic acid has been researched along with guanosine triphosphate in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (40.00) | 18.7374 |
| 1990's | 18 (30.00) | 18.2507 |
| 2000's | 12 (20.00) | 29.6817 |
| 2010's | 5 (8.33) | 24.3611 |
| 2020's | 1 (1.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kakiuchi, K; Matsuda, Y; Nakagawa, H; Ogawa, H; Shiraki, H | 1 |
| Clark, AW; Rudolph, FB | 1 |
| Izui, K; Kameshita, I; Katsuki, H; Tokushige, M | 1 |
| Markham, GD; Reed, GH | 1 |
| McGivan, JD; Moss, KM | 1 |
| Anborgh, PH; Clark, BF; Harmark, K; Merola, M; Parmeggiani, A | 1 |
| Cerpovicz, PF; Ochs, RS | 1 |
| Anborgh, PH; Cool, RH; Gümüşel, F; Parmeggiani, A; Weijland, A | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Bosch, L; Kraal, B; Parmeggiani, A; Swart, GW | 1 |
| Hwang, YW; Miller, DL | 1 |
| Buniatian, GKh | 1 |
| Coleman, MS; Jones, ME | 1 |
| Garber, AJ; Hanson, RW | 1 |
| Kelly, WN; Van der Weyden, MB | 1 |
| London, RE; Schmidt, PG | 1 |
| Sanwal, BD; Smando, R; Waygood, EB | 1 |
| Eyzaguirre, J | 1 |
| Hollander, V; Lowenstein, JM | 1 |
| Cashel, M; Gallant, J; Irr, J | 1 |
| Lowenstein, JM; Tornheim, K | 1 |
| Lukas, MC; Maguire, MH; Rettie, JF | 1 |
| Cutinelli, L; Pietropaolo, C; Salvatore, F; Venuta, S; Zappia, V | 1 |
| Carta, F; Maraini, G; Pescatori, A; Prosperi, L | 1 |
| Clonis, YD; Lowe, CR | 1 |
| Izui, K; Katsuki, H; Morikawa, M; Taguchi, M | 1 |
| Erdei, S; Kari, C; Kondorosi, E; Riesenberg, D | 1 |
| Cavenagh, M; Clark, J; Kahn, RA; Randazzo, PA; Rulka, C; Stearns, T; Terui, T; Zhang, CJ | 1 |
| Fromm, HJ; Honzatko, RB; Kang, C; Sun, N | 1 |
| Farrar, CT; Halkides, CJ; Larsen, RG; Redfield, AG; Singel, DJ | 1 |
| Bell, GI; Kong, H; Moe, ST; Portoghese, PS; Raynor, K; Reisine, T; Yasuda, K | 1 |
| Gallaher, TK; Shih, JC; Wang, CD | 1 |
| Choong, YS; Gavin, JB | 1 |
| Clark, BF; Knudsen, CR | 1 |
| Egger, LA; Inouye, M; Lu, Q; Park, H | 1 |
| Clark, BF; Kjeldgaard, M; Nissen, P; Nyborg, J; Thirup, S | 1 |
| Cao, C; Huang, J; Lutkenhaus, J; Mukherjee, A; Wang, X | 1 |
| Hietala, OA; Kilpeläinen, PT | 1 |
| Cory, AH; Cory, JG | 1 |
| Choe, JY; Fromm, HJ; Honzatko, RB; Poland, BW | 1 |
| Krauss, G; Lipps, G | 1 |
| Krab, IM; Parmeggiani, A | 1 |
| Bienengraeber, M; Echtay, KS; Klingenberg, M; Winkler, E | 1 |
| de Wit, JG; den Blaauwen, T; Driessen, AJ; Scheffers, DJ | 1 |
| Gudkov, AT; Liljas, A; Martemyanov, KA; Yarunin, AS | 1 |
| Lamkin, MS; Lindhe, P | 1 |
| Balaram, H; Jayalakshmi, R; Sumathy, K | 1 |
| Inaoka, T; Ochi, K | 1 |
| Cerione, RA; Hahn, K; Nolbant, P; Tu, SS; Wu, WJ; Yang, W | 1 |
| Bearne, SL; Iyengar, A | 1 |
| Cabrera, M; Hidalgo, J; Martín, ME; Muñiz, M; Vega, L; Velasco, A | 1 |
| Collingridge, GL; Isaac, JT; Lauri, SE; Maingret, F; Mulle, C; Segerstråle, M; Taira, T; Vesikansa, A | 1 |
| Hausmann, S; Shuman, S | 1 |
| Likhoshvai, VA; Oshchepkova-Nedosekina, EA | 1 |
| Anand, B; Prakash, B; Surana, P | 1 |
| Gunda, SK; Mulukala Narasimha, SK; Shaik, M | 1 |
| Dannies, E; Maracci, C; Peske, F; Pohl, C; Rodnina, MV | 1 |
| Hou, W; Kong, J; Li, Y; Peng, X; Qin, X; Yu, XF | 1 |
| Balaram, H; Karnawat, V; Mehrotra, S; Puranik, M | 1 |
| Bhat, S; Bianchet, MA; Dong, L; Egleston, M; Greenberg, MM; Howlader, AH; Orris, B; Stivers, JT | 1 |
3 review(s) available for aspartic acid and guanosine triphosphate
| Article | Year |
|---|---|
[Mechanisms of ammonia formation in the brain].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Oxidoreductases; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Deamination; Dogs; Flavin-Adenine Dinucleotide; Fumarates; Glutamate Dehydrogenase; Glutaminase; Glutamine; Guanosine Triphosphate; Inosine Nucleotides; Mitochondria; Monoamine Oxidase; NAD; NADP; Nerve Tissue Proteins; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Rats | 1973 |
Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carboxy-Lyases; Cytosol; Fasting; Feeding Behavior; Gluconeogenesis; Guanosine Triphosphate; Guinea Pigs; Humans; Ligases; Liver; Malates; Mitochondria, Liver; NAD; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Rabbits; Rats; Species Specificity | 1972 |
The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Models, Structural; Peptide Elongation Factor Tu; Protein Binding; Protein Folding; RNA, Transfer, Phe; Saccharomyces cerevisiae; Thermus | 1996 |
57 other study(ies) available for aspartic acid and guanosine triphosphate
| Article | Year |
|---|---|
Purification, crystallization, and properties of adenylosuccinate synthetase from rat skeletal muscle.
Topics: Adenosine Monophosphate; Amino Acids; Animals; Aspartic Acid; Cations, Divalent; Cations, Monovalent; Fatty Acids, Nonesterified; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine Nucleotides; Kinetics; Ligases; Male; Molecular Weight; Muscles; Nucleotides; Rats; Succinates | 1977 |
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Carcinoma, Hepatocellular; Feedback; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Rats | 1976 |
Reversible desensitization of phosphoenolpyruvate carboxylase to multiple effectors by butanedione.
Topics: Acetyl Coenzyme A; Allosteric Site; Arginine; Aspartic Acid; Binding Sites; Borates; Butanones; Diacetyl; Escherichia coli; Guanosine Triphosphate; Kinetics; Lactates; Lauric Acids; Magnesium; Phosphoenolpyruvate Carboxykinase (GTP) | 1977 |
Reactions of phosphorothioate compounds catalyzed by adenylosuccinate synthetase. Steady state and pre-steady state kinetic studies.
Topics: Aspartic Acid; Azotobacter; Calcium; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Ligases; Magnesium; Organothiophosphorus Compounds; Spectrophotometry, Ultraviolet | 1978 |
Characteristics of aspartate deamination by the puring nucleotide cycle in the cytosol fraction of rat liver.
Topics: Adenosine Triphosphate; AMP Deaminase; Animals; Aspartic Acid; Cytosol; Deamination; Enzyme Activation; Female; Guanosine Triphosphate; Liver; Magnesium; Mitochondria, Liver; Purine Nucleotides; Rats | 1975 |
Substitution of aspartic acid-80, a residue involved in coordination of magnesium, weakens the GTP binding and strongly enhances the GTPase of the G domain of elongation factor Tu.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Edetic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Elongation Factor Tu; Protein Conformation | 1992 |
A radiochemical enzymatic endpoint assay for GTP and GDP.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Sensitivity and Specificity; Substrate Specificity | 1991 |
Mutagenesis of the NH2-terminal domain of elongation factor Tu.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Computer Graphics; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Thermodynamics; Urea; Valine | 1990 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Effects of the mutation glycine-222----aspartic acid on the functions of elongation factor Tu.
Topics: Aspartic Acid; Escherichia coli; Genes; Genes, Bacterial; Glycine; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Triphosphate; Kinetics; Mutation; Peptide Elongation Factor Tu | 1987 |
A mutation that alters the nucleotide specificity of elongation factor Tu, a GTP regulatory protein.
Topics: Asparagine; Aspartic Acid; Cloning, Molecular; Escherichia coli; Genes; Genes, Bacterial; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Mutation; Peptide Elongation Factor Tu; Plasmids; Protein Binding | 1987 |
Aspartate transcarbamylases of Citrobacter freundii.
Topics: Adenosine Triphosphate; Aspartic Acid; Carbamates; Centrifugation, Density Gradient; Chloromercuribenzoates; Chromatography, Gel; Cytidine; Cytosine; Cytosine Nucleotides; Diphosphates; Enzyme Activation; Escherichia; Guanosine Triphosphate; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Macromolecular Substances; Molecular Weight; Pentosephosphates; Phosphates; Phosphoric Acids; Ribose; Transferases; Uracil Nucleotides | 1971 |
Human adenylosuccinate synthetase. Partial purification, kinetic and regulatory properties of the enzyme from placenta.
Topics: Aspartic Acid; Binding, Competitive; Carbon Radioisotopes; Cations, Divalent; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Female; Guanine Nucleotides; Guanosine Triphosphate; Humans; Inosine Nucleotides; Kinetics; Ligases; Placenta; Pregnancy; Purine Nucleotides; Purines; Pyrimidines; Ribonucleosides; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
A model for nucleotide regulation of aspartate transcarbamylase.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Aspartic Acid; Binding Sites; Carbamates; Cytidine; Cytosine; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Guanosine Triphosphate; Inosine; Inosine Nucleotides; Kinetics; Mathematics; Models, Chemical; Nucleotides; Phosphoric Acids; Protein Conformation; Radioisotopes; Transferases | 1972 |
Cooperative interactions in the binding of allosteric effectors to phosphoenolpyruvate carboxylase.
Topics: Acetyl Coenzyme A; Allosteric Regulation; Amino Acid Sequence; Aspartic Acid; Binding Sites; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Gel; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Guanidines; Guanosine Triphosphate; Kinetics; Magnesium; Manganese; Molecular Weight; Peptide Fragments; Phosphates; Phosphoenolpyruvate; Protein Binding; Salmonella typhimurium; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Ultracentrifugation | 1974 |
Stray light interference in the spectrophotometric measurement of enzyme activity and determination of kinetic parameters.
Topics: Aspartic Acid; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Chromatography, Thin Layer; Escherichia coli; Evaluation Studies as Topic; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Ligases; Light; Magnesium; Methods; Protein Binding; Spectrophotometry, Ultraviolet | 1974 |
The purine nucleotide cycle. The production of ammonia from aspartate by brain and muscle.
Topics: Adenosine Monophosphate; Aminohydrolases; Ammonia; Ammonium Sulfate; Animals; Aspartic Acid; Brain; Brain Chemistry; Cell-Free System; Fumarates; Glucose; Guanosine Triphosphate; Hexokinase; Inosine Nucleotides; Ligases; Lyases; Malates; Muscles; Nucleotides; Phosphates; Phosphocreatine; Potassium; Rats; Spectrophotometry; Subcellular Fractions; Succinates | 1973 |
The mechanism of amino acid control of guanylate and adenylate biosynthesis.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Aspartic Acid; Carbon Isotopes; Escherichia coli; Feedback; Genes; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Isoleucine; Ligases; Mutation; Nucleotides; Operon; Oxidoreductases; Species Specificity; Stimulation, Chemical; Uracil; Valine | 1971 |
The purine nucleotide cycle. The production of ammonia from aspartate by extracts of rat skeletal muscle.
Topics: Adenosine Monophosphate; Amination; Ammonia; Animals; Aspartic Acid; Catalysis; Creatine; Deamination; Depression, Chemical; Fumarates; Guanine Nucleotides; Guanosine Triphosphate; Hexoses; Inosine Nucleotides; Malates; Male; Muscles; Nucleotides; Phosphoric Acids; Purine Nucleotides; Rats; Stimulation, Chemical; Succinates | 1972 |
Adenine nucleotide salvage synthesis in the rat heart; pathways of adnosine salvage.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Aminohydrolases; Animals; Aspartic Acid; Carbon Isotopes; Female; Guanosine Triphosphate; Hypoxanthines; Inosine Nucleotides; Kinetics; Ligases; Lyases; Male; Myocardium; Pentosephosphates; Pentosyltransferases; Phosphotransferases; Rats; Spectrophotometry; Succinates; Ultraviolet Rays; Xanthine Oxidase | 1972 |
Studies on the identification and characterization of an aspartase activity in liver of elasmobranch fishes.
Topics: Aerobiosis; Ammonia; Amphibians; Anaerobiosis; Animals; Aspartic Acid; Birds; Cell Fractionation; Centrifugation, Density Gradient; Deamination; Fishes; Guanosine Triphosphate; Inosine Nucleotides; Ketoglutaric Acids; Liver; Lyases; Mitochondria, Liver; Nitrogen Isotopes; Reptiles; Rodentia; Species Specificity | 1972 |
Protein metabolism in human senile cataract.
Topics: Adenosine Triphosphate; Aged; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Cataract; Crystallins; Guanosine Triphosphate; Humans; Lens, Crystalline; Leucine; Rabbits; Tritium | 1971 |
Affinity chromatography on immobilised triazine dyes. Studies on the interaction with multinucleotide-dependent enzymes.
Topics: Adenylosuccinate Synthase; Anthracenes; Aspartic Acid; Binding Sites; Chromatography, Affinity; Coloring Agents; Escherichia coli; Guanosine Triphosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Ligases; Triazines | 1981 |
Regulation of Escherichia coli phosphoenolpyruvate carboxylase by multiple effectors in vivo. Estimation of the activities in the cells grown on various compounds.
Topics: Acetyl Coenzyme A; Allosteric Regulation; Aspartic Acid; Carboxy-Lyases; Carboxylic Acids; Escherichia coli; Fructosediphosphates; Glucose; Glycerol; Guanosine Triphosphate; Lactates; Phosphoenolpyruvate Carboxylase | 1980 |
Positive involvement of ppGpp in derepression of the nif operon in Klebsiella pneumoniae.
Topics: Adenine; Adenosine Triphosphate; Anaerobiosis; Aspartic Acid; Cell Division; Gene Expression Regulation; Genes, Bacterial; Guanine Nucleotides; Guanosine Tetraphosphate; Guanosine Triphosphate; Klebsiella pneumoniae; Nitrogen; Nitrogenase; Operon | 1982 |
Mutational analysis of Saccharomyces cerevisiae ARF1.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Alleles; Amino Acid Sequence; Aspartic Acid; Cysteine; DNA Mutational Analysis; Genes, Dominant; Genes, Lethal; GTP-Binding Proteins; Guanosine Triphosphate; Molecular Sequence Data; Point Mutation; Protein Binding; Saccharomyces cerevisiae | 1995 |
Replacement of Asp333 with Asn by site-directed mutagenesis changes the substrate specificity of Escherichia coli adenylosuccinate synthetase from guanosine 5'-triphosphate to xanthosine 5'-triphosphate.
Topics: Adenylosuccinate Synthase; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Circular Dichroism; DNA, Complementary; Escherichia coli; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Ribonucleotides; Substrate Specificity | 1994 |
Characterization of the active site of p21 ras by electron spin-echo envelope modulation spectroscopy with selective labeling: comparisons between GDP and GTP forms.
Topics: Asparagine; Aspartic Acid; Binding Sites; Electron Spin Resonance Spectroscopy; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Ligands; Phosphates; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Threonine | 1994 |
A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Colforsin; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Oligodeoxyribonucleotides; Protein Binding; Receptors, Opioid, delta; Recombinant Proteins; Signal Transduction; Sodium; Structure-Activity Relationship | 1993 |
Site-directed mutagenesis of the serotonin 5-hydroxytrypamine2 receptor: identification of amino acids necessary for ligand binding and receptor activation.
Topics: 3T3 Cells; Amphetamines; Animals; Asparagine; Aspartic Acid; Binding, Competitive; Guanosine Triphosphate; Hydrolysis; Lysergic Acid Diethylamide; Mice; Mutagenesis, Site-Directed; Phosphatidylinositols; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Functional, metabolic and ultrastructure evidence for improved myocardial protection during severe ischaemic stress with MBS, a new crystalloid cardioplegic solution.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Disaccharides; Glucose; Guanosine Triphosphate; Heart; Heart Arrest, Induced; Hemodynamics; Magnesium; Male; Microscopy, Electron; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Potassium Chloride; Rats; Rats, Wistar; Sodium Chloride; Time Factors | 1996 |
Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding.
Topics: Anti-Bacterial Agents; Arginine; Aspartic Acid; Base Sequence; DNA Primers; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Binding; Pyridones; Recombinant Proteins; Ribosomes; RNA, Transfer; RNA, Transfer, Phe | 1995 |
Nucleoside-diphosphate kinase-mediated signal transduction via histidyl-aspartyl phosphorelay systems in Escherichia coli.
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Guanosine Triphosphate; Histidine; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Multienzyme Complexes; Nucleoside-Diphosphate Kinase; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinases; Signal Transduction | 1996 |
Analysis of the interaction of FtsZ with itself, GTP, and FtsA.
Topics: Asparagine; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Cytoskeletal Proteins; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; Guanosine Triphosphate; Mutagenesis, Site-Directed; Peptide Fragments; Polymers; Protein Binding; Recombinant Fusion Proteins; Sequence Analysis; Trypsin | 1997 |
Mutation of aspartate-233 to valine in mouse ornithine decarboxylase reduces enzyme activity.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; CHO Cells; Conserved Sequence; Cricetinae; DNA, Complementary; Enzyme Activation; Guanosine Triphosphate; Kinetics; Mammary Tumor Virus, Mouse; Mice; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Point Mutation; Promoter Regions, Genetic; Rats; Transfection; Valine | 1998 |
Cellular responses in mouse leukemia L1210 cells made resistant to deoxyadenosine.
Topics: Animals; Apoptosis; Aspartic Acid; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Guanosine Triphosphate; Isoxazoles; Leukemia L1210; Mice; Nucleotides; Phosphonoacetic Acid; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli.
Topics: Adenylosuccinate Synthase; Aspartic Acid; Binding Sites; Crystallization; Crystallography, X-Ray; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Inosine Monophosphate; Magnesium; Models, Molecular; Mutagenesis, Site-Directed | 1999 |
Adenylosuccinate synthase from Saccharomyces cerevisiae: homologous overexpression, purification and characterization of the recombinant protein.
Topics: Adenine Nucleotides; Adenylosuccinate Synthase; Aspartic Acid; Chromatography, Gel; Cloning, Molecular; Escherichia coli; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine Monophosphate; Kinetics; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 1999 |
Mutagenesis of three residues, isoleucine-60, threonine-61, and aspartic acid-80, implicated in the GTPase activity of Escherichia coli elongation factor Tu.
Topics: Aspartic Acid; Binding Sites; Escherichia coli; Esters; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Isoleucine; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Peptides; Pyridones; Recombinant Proteins; Ribosomes; RNA, Transfer, Phe; Threonine | 1999 |
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions.
Topics: Adipose Tissue, Brown; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Chlorides; Cricetinae; Electron Transport; Glutamic Acid; Glutamine; Guanosine Triphosphate; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1 | 2000 |
Substitution of a conserved aspartate allows cation-induced polymerization of FtsZ.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Cations, Divalent; Cytoskeletal Proteins; Guanosine Triphosphate; Mutagenesis, Site-Directed; Polymers | 2001 |
Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.
Topics: Alanine; Aspartic Acid; Binding Sites; Cell-Free System; Fusidic Acid; Genetic Variation; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Poly U; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; Thermus thermophilus; Threonine | 2001 |
Purification of kinase activity from primate parotid glands.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Chromatography, Affinity; Enzyme Inhibitors; Enzymes, Immobilized; Glutamic Acid; Glycoproteins; Golgi Apparatus; Guanosine Triphosphate; Heparin; Histatins; Hydrogen-Ion Concentration; Macaca fascicularis; Parotid Gland; Phosphopeptides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Salivary Proteins and Peptides; Serine; Substrate Specificity | 2001 |
Purification and characterization of recombinant Plasmodium falciparum adenylosuccinate synthetase expressed in Escherichia coli.
Topics: Adenylosuccinate Synthase; Animals; Aspartic Acid; Blotting, Western; Chromatography, Gel; Cloning, Molecular; Dimerization; DNA, Complementary; Edetic Acid; Escherichia coli; Genetic Complementation Test; Glycerol; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Models, Chemical; Plasmodium falciparum; Recombinant Proteins | 2002 |
RelA protein is involved in induction of genetic competence in certain Bacillus subtilis strains by moderating the level of intracellular GTP.
Topics: Adenosine; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; DNA-Binding Proteins; Guanosine Monophosphate; Guanosine Triphosphate; Ligases; Repressor Proteins; Spores, Bacterial | 2002 |
Antiapoptotic Cdc42 mutants are potent activators of cellular transformation.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Apoptosis; Asparagine; Aspartic Acid; cdc42 GTP-Binding Protein; Cell Division; Cell Transformation, Neoplastic; COS Cells; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Mice; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Binding; Trans-Activators; Transfection | 2002 |
Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Carbon-Nitrogen Ligases; Circular Dichroism; Conserved Sequence; Cytidine Triphosphate; Dimerization; Escherichia coli Proteins; Glutamine; Guanosine Triphosphate; Hydrolysis; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed | 2003 |
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Animals; Aspartic Acid; Cell Compartmentation; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum; Fluorescent Antibody Technique; Golgi Apparatus; GTPase-Activating Proteins; Guanosine Triphosphate; Isoquinolines; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Peptide; Serine; Signal Transduction; Sulfonamides | 2003 |
Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus.
Topics: Animals; Animals, Newborn; Aspartic Acid; Baclofen; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Furans; GABA Agonists; GABA Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Interneurons; Isoquinolines; Isoxazoles; Membrane Potentials; Mice; Mice, Knockout; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Probability; Receptors, Kainic Acid | 2005 |
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Giardia lamblia; Glutamic Acid; Glycerol; Green Fluorescent Proteins; Guanine; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methylation; Methyltransferases; Molecular Sequence Data; Recombinant Proteins; RNA; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Transfection; tRNA Methyltransferases; Tryptophan | 2005 |
A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis.
Topics: Adenylosuccinate Synthase; Aspartic Acid; Enzyme Inhibitors; Escherichia coli; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Magnesium; Models, Biological; Purines; Substrate Specificity | 2007 |
Deciphering the catalytic machinery in 30S ribosome assembly GTPase YqeH.
Topics: Aspartic Acid; Bacillus subtilis; Catalysis; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Potassium; Ribosome Subunits, Small, Bacterial; Sequence Homology, Amino Acid | 2010 |
Comparative modeling of Rab6 proteins: identification of key residues and their interactions with guanine nucleotides.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Caenorhabditis elegans; Chickens; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Mice; Molecular Docking Simulation; Molecular Sequence Data; Protein Binding; rab GTP-Binding Proteins; Sequence Alignment; Serine; Structural Homology, Protein | 2013 |
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Codon; GTP Phosphohydrolases; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Conformation; Molecular Structure; Mutation; Peptide Elongation Factor Tu; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Transfer, Amino Acyl | 2014 |
Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Cell Cycle; Crystallography, X-Ray; Escherichia coli; Guanosine Triphosphate; Histidine; Humans; Hydrolysis; Immunity, Innate; Macrophages; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Plasmids; Protein Multimerization; Protein Structure, Tertiary; Recombinant Proteins; SAM Domain and HD Domain-Containing Protein 1; Sequence Homology, Amino Acid | 2015 |
Exquisite Modulation of the Active Site of Methanocaldococcus jannaschii Adenylosuccinate Synthetase in Forward Reaction Complexes.
Topics: Adenosine Monophosphate; Adenylosuccinate Synthase; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Glycine; Guanosine Triphosphate; Inosine Monophosphate; Kinetics; Ligands; Methanocaldococcus; Models, Molecular; Protein Conformation | 2016 |
Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding.
Topics: Aspartic Acid; Deoxyguanosine; Guanosine Triphosphate; Histidine; Monomeric GTP-Binding Proteins; Nucleic Acids; SAM Domain and HD Domain-Containing Protein 1; Sterile Alpha Motif | 2023 |