aspartic acid has been researched along with guanosine diphosphate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 12 (52.17) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anborgh, PH; Clark, BF; Harmark, K; Merola, M; Parmeggiani, A | 1 |
| Cerpovicz, PF; Ochs, RS | 1 |
| Anborgh, PH; Cool, RH; Gümüşel, F; Parmeggiani, A; Weijland, A | 1 |
| Papastavros, MZ; Redfield, AG | 1 |
| Campbell-Burk, S | 1 |
| Hwang, YW; Miller, DL | 1 |
| Adra, CN; Cerione, RA; Leonard, DA; Lim, B; Platko, JV; Shaw, RJ | 1 |
| Farrar, CT; Halkides, CJ; Larsen, RG; Redfield, AG; Singel, DJ | 1 |
| Li, X; Spremulli, LL; Zhang, Y | 1 |
| Clark, BF; Knudsen, CR | 1 |
| Antonny, B; Béraud-Dufour, S; Chabre, M; Chardin, P; Cherfils, J; Paris, S; Robineau, S | 1 |
| Choe, JY; Fromm, HJ; Honzatko, RB; Poland, BW | 1 |
| Akeson, M; Battey, JF; Donohue, PJ; Jensen, RT; Kroog, GS; Mantey, SA; Northup, JK; Sainz, E | 1 |
| Krab, IM; Parmeggiani, A | 1 |
| Dumas, JJ; Lambright, DG; Lietzke, SE; Zhu, Z | 1 |
| Brune, M; Corrie, JE; Webb, MR | 1 |
| Gudkov, AT; Liljas, A; Martemyanov, KA; Yarunin, AS | 1 |
| Cerione, RA; Hahn, K; Nolbant, P; Tu, SS; Wu, WJ; Yang, W | 1 |
| Cooperman, BS; Kashlan, OB | 1 |
| Hains, MD; Jones, MB; Kimple, RJ; Nweke, GK; Siderovski, DP; Willard, FS | 1 |
| Hume, JR; Wang, GX; Yamamoto-Mizuma, S | 1 |
| Dehlin, EM; Fang, H; Jhaveri, S; Kamatchi, GL; Oronce, CI; Rajagopal, S; Sando, JJ; Snyder, SL; Taneja, S | 1 |
| Gunda, SK; Mulukala Narasimha, SK; Shaik, M | 1 |
23 other study(ies) available for aspartic acid and guanosine diphosphate
| Article | Year |
|---|---|
Substitution of aspartic acid-80, a residue involved in coordination of magnesium, weakens the GTP binding and strongly enhances the GTPase of the G domain of elongation factor Tu.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Edetic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Elongation Factor Tu; Protein Conformation | 1992 |
A radiochemical enzymatic endpoint assay for GTP and GDP.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Sensitivity and Specificity; Substrate Specificity | 1991 |
Mutagenesis of the NH2-terminal domain of elongation factor Tu.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Computer Graphics; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Thermodynamics; Urea; Valine | 1990 |
NMR study of the phosphoryl binding loop in purine nucleotide proteins: evidence for strong hydrogen bonding in human N-ras p21.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Escherichia coli; Glycine; Guanosine Diphosphate; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Protein Conformation; Recombinant Proteins | 1990 |
Structural and dynamic differences between normal and transforming N-ras gene products: a 31P and isotope-edited 1H NMR study.
Topics: Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry, Physical; Glycine; Guanosine Diphosphate; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Spectrum Analysis | 1989 |
A mutation that alters the nucleotide specificity of elongation factor Tu, a GTP regulatory protein.
Topics: Asparagine; Aspartic Acid; Cloning, Molecular; Escherichia coli; Genes; Genes, Bacterial; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Mutation; Peptide Elongation Factor Tu; Plasmids; Protein Binding | 1987 |
A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Drug Design; Glutathione Transferase; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Humans; Isoleucine; Mice; Molecular Sequence Data; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Restriction Mapping; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Sequence Deletion; Sequence Homology, Amino Acid | 1995 |
Characterization of the active site of p21 ras by electron spin-echo envelope modulation spectroscopy with selective labeling: comparisons between GDP and GTP forms.
Topics: Asparagine; Aspartic Acid; Binding Sites; Electron Spin Resonance Spectroscopy; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Ligands; Phosphates; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Threonine | 1994 |
Role of the conserved aspartate and phenylalanine residues in prokaryotic and mitochondrial elongation factor Ts in guanine nucleotide exchange.
Topics: Aspartic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine Nucleotides; Guanosine Diphosphate; Peptide Elongation Factors; Phenylalanine; Poly U; Structure-Activity Relationship | 1996 |
Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding.
Topics: Anti-Bacterial Agents; Arginine; Aspartic Acid; Base Sequence; DNA Primers; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Binding; Pyridones; Recombinant Proteins; Ribosomes; RNA, Transfer; RNA, Transfer, Phe | 1995 |
A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Aspartic Acid; Binding Sites; Fungal Proteins; Glutamic Acid; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Phosphates; Protein Conformation | 1998 |
Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli.
Topics: Adenylosuccinate Synthase; Aspartic Acid; Binding Sites; Crystallization; Crystallography, X-Ray; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Inosine Monophosphate; Magnesium; Models, Molecular; Mutagenesis, Site-Directed | 1999 |
An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.
Topics: 3T3 Cells; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Catalysis; Clone Cells; Extracellular Space; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Receptors, Bombesin | 1999 |
Mutagenesis of three residues, isoleucine-60, threonine-61, and aspartic acid-80, implicated in the GTPase activity of Escherichia coli elongation factor Tu.
Topics: Aspartic Acid; Binding Sites; Escherichia coli; Esters; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Isoleucine; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Peptides; Pyridones; Recombinant Proteins; Ribosomes; RNA, Transfer, Phe; Threonine | 1999 |
A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Conserved Sequence; Evolution, Molecular; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Helix-Turn-Helix Motifs; Kinetics; Mice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Proteins; rab GTP-Binding Proteins; Rats; Sequence Homology, Amino Acid; Serine | 2001 |
A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Binding Sites; Coumarins; Cysteine; Fluorescent Dyes; Guanosine Diphosphate; Humans; Kinetics; Mass Spectrometry; Mutagenesis, Site-Directed; Myosin Subfragments; Myxococcus xanthus; Nucleoside-Diphosphate Kinase; Phosphorylation; Purine Nucleotides; Rabbits; rho GTP-Binding Proteins; Solutions; Spectrometry, Fluorescence | 2001 |
Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.
Topics: Alanine; Aspartic Acid; Binding Sites; Cell-Free System; Fusidic Acid; Genetic Variation; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Poly U; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; Thermus thermophilus; Threonine | 2001 |
Antiapoptotic Cdc42 mutants are potent activators of cellular transformation.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Apoptosis; Asparagine; Aspartic Acid; cdc42 GTP-Binding Protein; Cell Division; Cell Transformation, Neoplastic; COS Cells; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Mice; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Binding; Trans-Activators; Transfection | 2002 |
Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Asparagine; Aspartic Acid; Cytidine Diphosphate; Deoxyadenine Nucleotides; Dimerization; Enzyme Activation; Guanosine Diphosphate; Kinetics; Light; Magnesium; Mice; Models, Chemical; Mutagenesis, Site-Directed; Protein Subunits; Recombinant Proteins; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Scattering, Radiation; Substrate Specificity; Thymine Nucleotides; Tumor Cells, Cultured | 2003 |
Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gi-Go; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Molecular Sequence Data; Mutation | 2004 |
P2Y purinergic receptor regulation of CFTR chloride channels in mouse cardiac myocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Gadolinium; Glucosamine; Glyburide; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Patch-Clamp Techniques; Pertussis Toxin; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sodium; Suramin; Thionucleotides; Zinc | 2004 |
Site-specific regulation of CA(V)2.2 channels by protein kinase C isozymes betaII and epsilon.
Topics: Animals; Aspartic Acid; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; Guanosine Diphosphate; Membrane Potentials; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Structure, Tertiary; RNA, Small Interfering; Serine; Thionucleotides; Threonine; Xenopus laevis; Xenopus Proteins | 2009 |
Comparative modeling of Rab6 proteins: identification of key residues and their interactions with guanine nucleotides.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Caenorhabditis elegans; Chickens; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Mice; Molecular Docking Simulation; Molecular Sequence Data; Protein Binding; rab GTP-Binding Proteins; Sequence Alignment; Serine; Structural Homology, Protein | 2013 |