Page last updated: 2024-08-17

aspartic acid and glucagon

aspartic acid has been researched along with glucagon in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199019 (45.24)18.7374
1990's12 (28.57)18.2507
2000's5 (11.90)29.6817
2010's6 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bever, K; Chenoweth, M; Dunn, A1
Kokas, P; Kupcsulik, P1
Horváth, M; Mestyán, J; Schultz, K; Soltész, G1
Cohen, BD; Handelsman, DG; Pai, BN1
D'Souza, NB; Deaciuc, IV; Lang, CH; Spitzer, JJ1
Arai, T; Ikeda, H; Oki, Y; Sasaki, M; Shiomi, M1
Hreniuk, S; LaNoue, KF; Scaduto, RC; Sterniczuk, A1
Arai, T; Oki, Y; Sasaki, M; Usui, T1
Filer, LJ; Stegink, LD1
Koch, CD; LaNoue, KF; Strzelecka, D; Strzelecki, T1
Andreu, D; Merrifield, RB1
Clarke, S; Ding, L; Ota, IM1
Groen, AK; Leverve, XM; Meijer, AJ; Tager, JM; Verhoeven, AJ1
Federman, M; Greengard, O; Knox, WE1
Claus, TH; Exton, JH; Park, CR; Ui, M1
Exton, JH; Park, CR; Ui, M2
Kneer, NM; Lardy, HA; Stratman, FW; Zahlten, RN1
Veneziale, CM1
Krebs, HA; Nishiitsutsuji-Uwo, JM; Ross, BD1
Campistron, G; Creuzet, MH; Franchimont, P; Gros, J; Luyckx, A1
Carruthers, CJ; Kim, HN; Sakmar, TP; Unson, CG1
Merrifield, RB; Unson, CG; Wu, CR1
Blazquez, E; Calvo, JC; Gisolfi, CV; Mora, F1
Kamo, M; Kawakami, T; Miyazaki, K; Nozawa, T; Shen, R; Takayama, M; Tsugita, A1
Ahn, JM; Azizeh, BY; Burley, SK; Hruby, VJ; Krstenansky, JL; Lin, Y; Sturm, NS; Trivedi, D1
Goto, N; Kameyama, T; Oka, JI1
Brosnan, JT; Brosnan, ME; Nissim, I; Yudkoff, M1
Arnold, M; Bitzi, R; Colombani, PC; Frey, W; Frey-Rindova, P; Langhans, W; Wenk, C1
Donnelly, D; López de Maturana, R1
Brauner-Osborne, H; Gram, C; Knudsen, LB; Madsen, K; Runge, S; Wulff, BS1
Hall, WL; Millward, DJ; Morgan, LM; Rogers, PJ1
ALLISON, H; GRICE, M; SCHULTZ, J1
FIRNHABER, S; LOHMANN, D1
Joshi, AB; Kirsch, LE1
Joshi, AB; Kearney, WR; Kirsch, LE; Sawai, M1
Chabenne, JR; DiMarchi, MA; DiMarchi, RD; Gelfanov, VM1
del Rio, RM; Feldmann, N; Gjinovci, A; Tamarit-Rodriguez, J; Wiederkehr, A; Wollheim, CB1
Han, W; Lee, P; Leong, W; Lim, M; Radda, GK; Tan, T1
Adriaenssens, AE; Andersson, LE; Bagge, A; Gribble, F; Mulder, H; Reimann, F; Sharoyko, VV; Spégel, P; Stamenkovic, JA; Wollheim, CB1
Hou, Y; Hu, CA; Leng, W; Li, S; Liu, Y; Pi, D; Shi, H; Tu, Z; Wang, X; Zhu, H1
Harada, N; Ikeda, K; Inagaki, N; Joo, E; Mano, F; Yamane, S1

Reviews

1 review(s) available for aspartic acid and glucagon

ArticleYear
Additional possible tools for identification of proteins on one- or two-dimensional electrophoresis.
    Electrophoresis, 1998, Volume: 19, Issue:6

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Carbonic Anhydrases; Cattle; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glucagon; Humans; Mass Spectrometry; Molecular Sequence Data; Muramidase; Peptide Mapping; Proteins; Sequence Analysis; Serine; Threonine

1998

Trials

2 trial(s) available for aspartic acid and glucagon

ArticleYear
Chronic arginine aspartate supplementation in runners reduces total plasma amino acid level at rest and during a marathon run.
    European journal of nutrition, 1999, Volume: 38, Issue:6

    Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Ammonia; Arginine; Aspartic Acid; Carbohydrates; Creatine Kinase; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Fatty Acids; Glucagon; Glycerol; Human Growth Hormone; Humans; Hydrocortisone; Insulin; L-Lactate Dehydrogenase; Male; Ornithine; Respiratory Function Tests; Running; Urea

1999
Physiological mechanisms mediating aspartame-induced satiety.
    Physiology & behavior, 2003, Volume: 78, Issue:4-5

    Topics: Adult; Appetite; Aspartame; Aspartic Acid; Blood Glucose; Cholecystokinin; Cross-Over Studies; Diet; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Hormones; Humans; Insulin; Male; Peptide Fragments; Phenylalanine; Protein Precursors; Satiety Response; Sweetening Agents

2003

Other Studies

39 other study(ies) available for aspartic acid and glucagon

ArticleYear
Use of 3H and 14C doubly labeled glucose and amino acids in the study of hormonal regulation of gluconeogenesis in rats.
    Federation proceedings, 1977, Volume: 36, Issue:2

    Topics: Adrenalectomy; Alanine; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glucose; Glutamates; Male; Phosphofructokinase-1; Rats; Stimulation, Chemical; Streptozocin; Tritium

1977
Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver.
    Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:4

    Topics: Adenosine Triphosphate; Allopurinol; Animals; Aspartic Acid; Chlorides; Glucagon; Ischemia; Liver; Liver Regeneration; Magnesium; Methylprednisolone; Phenoxybenzamine; Rats

1979
The metabolic effects of glucagon infusion in normoglycaemic and hypoglycaemic small-for-gestational-age infants. II. Changes in plasma amino acids.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1976, Volume: 17, Issue:3

    Topics: Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Citrulline; Glucagon; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Infant, Low Birth Weight; Infant, Newborn; Infant, Small for Gestational Age; Infusions, Parenteral; Isoleucine; Leucine; Liver; Proline; Valine

1976
Toxicity arising from the urea cycle.
    Kidney international. Supplement, 1975, Issue:3

    Topics: Animals; Arginine; Aspartic Acid; Dogs; Glucagon; Glycogen; Guanidines; Insulin; Insulin Secretion; Liver; Pancreas; Rats; Urea; Uremia

1975
Effects of acute alcohol intoxication on gluconeogenesis and its hormonal responsiveness in isolated, perfused rat liver.
    Biochemical pharmacology, 1992, Oct-20, Volume: 44, Issue:8

    Topics: Adenine Nucleotides; Alcoholic Intoxication; Animals; Aspartic Acid; Dinoprost; Dose-Response Relationship, Drug; Ethanol; Glucagon; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Lactates; Liver; Malates; Male; Perfusion; Phenylephrine; Pyruvates; Rats; Rats, Sprague-Dawley

1992
Changes in plasma insulin and glucagon concentrations and hepatic enzyme activities in diabetic voles treated with monosodium aspartate.
    The Journal of veterinary medical science, 1991, Volume: 53, Issue:3

    Topics: Animals; Arvicolinae; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fructose-Bisphosphatase; Glucagon; Glucokinase; Insulin; Liver

1991
The mechanism of Ca2(+)-related control of gluconeogenesis in perfused liver.
    European journal of biochemistry, 1991, Feb-26, Volume: 196, Issue:1

    Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Glucagon; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Phenylephrine; Rats; Tetradecanoylphorbol Acetate

1991
Immunohistochemical, ultrastructural, and hormonal studies on the endocrine pancreas of voles (Microtus arvalis) with monosodium aspartate-induced diabetes.
    Veterinary pathology, 1991, Volume: 28, Issue:6

    Topics: Animals; Arvicolinae; Aspartic Acid; Blood Glucose; Cytoplasmic Granules; Diabetes Mellitus, Experimental; Female; Glucagon; Hyperplasia; Hypertrophy; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Microscopy, Electron; Rodent Diseases; Somatostatin

1991
Aspartame metabolism in normal adults, phenylketonuric heterozygotes, and diabetic subjects.
    Diabetes care, 1989, Volume: 12, Issue:1

    Topics: Adult; Aspartame; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Erythrocytes; Female; Glucagon; Heterozygote; Humans; Insulin; Lipids; Male; Methanol; Phenylalanine; Phenylketonurias; Reference Values

1989
Sites of action of glucagon and other Ca2+ mobilizing hormones on the malate aspartate cycle.
    Archives of biochemistry and biophysics, 1988, Volume: 264, Issue:1

    Topics: Animals; Aspartic Acid; Binding Sites; Calcium; Glucagon; Glutamates; Glutamic Acid; Intracellular Membranes; Ketoglutaric Acids; Malates; Mitochondria, Liver; Onium Compounds; Organophosphorus Compounds; Oxidation-Reduction; Rats; Rats, Inbred Strains

1988
Glucagon antagonists. Synthesis and inhibitory properties of Asp3-containing glucagon analogs.
    European journal of biochemistry, 1987, May-04, Volume: 164, Issue:3

    Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Enzyme Activation; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Secretin

1987
Methylation at specific altered aspartyl and asparaginyl residues in glucagon by the erythrocyte protein carboxyl methyltransferase.
    The Journal of biological chemistry, 1987, Jun-25, Volume: 262, Issue:18

    Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Brain; Chymotrypsin; Erythrocytes; Glucagon; Humans; Methylation; Peptide Fragments; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Substrate Specificity; Trypsin

1987
The malate/aspartate shuttle and pyruvate kinase as targets involved in the stimulation of gluconeogenesis by phenylephrine.
    European journal of biochemistry, 1986, Mar-17, Volume: 155, Issue:3

    Topics: Animals; Aspartic Acid; Biological Transport; Cytosol; Dihydroxyacetone; Ethanol; Glucagon; Gluconeogenesis; Glycerol; In Vitro Techniques; Lactates; Lactic Acid; Liver; Malates; Male; Oxidation-Reduction; Phenylephrine; Pyruvate Kinase; Rats; Rats, Inbred Strains

1986
Cytomorphometry of developing rat liver and its application to enzymic differentiation.
    The Journal of cell biology, 1972, Volume: 52, Issue:2

    Topics: Aging; Animals; Aspartic Acid; Cell Count; Female; Glucagon; Glucokinase; Glucosyltransferases; Glycogen; Hematopoietic Stem Cells; Humans; Hydrocortisone; Infant, Newborn; Liver; Organ Size; Phosphoric Monoester Hydrolases; Pregnancy; Rats; Rats, Inbred Strains; Serine; Thyroxine; Transferases; Tyrosine Transaminase

1972
Studies on the mechanism of action of glucagon on gluconeogenesis.
    The Journal of biological chemistry, 1973, Aug-10, Volume: 248, Issue:15

    Topics: Animals; Aspartic Acid; Bicarbonates; Carbon Radioisotopes; Citrates; Fasting; Glucagon; Gluconeogenesis; Lactates; Liver; Malates; Male; Oxaloacetates; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Rats; Time Factors; Tryptophan

1973
Effects of glucagon on glutamate metabolism in the perfused rat liver.
    The Journal of biological chemistry, 1973, Aug-10, Volume: 248, Issue:15

    Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Erythrocytes; Fumarates; Glucagon; Gluconeogenesis; Glutamates; Glutamine; Ketoglutaric Acids; Lactates; Liver; Liver Glycogen; Male; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Rats; Succinates; Time Factors

1973
The influence of ammonium and calcium lons on gluconeogenesis in isolated rat hepatocytes and their response to glucagon and epinephrine.
    Archives of biochemistry and biophysics, 1974, Apr-02, Volume: 161, Issue:2

    Topics: Acetates; Animals; Aspartic Acid; Calcium; Epinephrine; Glucagon; Gluconeogenesis; Glutamates; Hydroxylamines; In Vitro Techniques; Kinetics; Lactates; Liver; Malonates; Quaternary Ammonium Compounds; Stimulation, Chemical; Time Factors

1974
Gluconeogenesis from fructose in isolated rat liver. Stimulation by glucagon.
    Biochemistry, 1971, Aug-31, Volume: 10, Issue:18

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aspartic Acid; Carbon Isotopes; Carboxy-Lyases; Chromatography, Paper; Electrophoresis, Paper; Fructose; Fructosephosphates; Glucagon; Gluconeogenesis; Glucosephosphates; Glyceric Acids; Glycerophosphates; In Vitro Techniques; Lactates; Liver; Malates; Male; Methods; Perfusion; Phosphoenolpyruvate; Pyridines; Pyruvates; Rats; Time Factors

1971
Mechanism of glucagon action on gluconeogenesis.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1970, Volume: 351, Issue:3

    Topics: Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Glucagon; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Lactates; Liver; Liver Glycogen; Perfusion; Pyruvates; Rats; Stimulation, Chemical

1970
Metabolic activities of the isolated perfused rat kidney.
    The Biochemical journal, 1967, Volume: 103, Issue:3

    Topics: Acetoacetates; Adenine Nucleotides; Animals; Aspartic Acid; Fumarates; Glucagon; Gluconeogenesis; Glucose; Glutamates; Glycerol; In Vitro Techniques; Kidney; Lactates; Ligases; Liver; Malates; Male; Oxygen Consumption; Perfusion; Pyruvates; Rats; Serum Albumin; Succinates; Urine

1967
Effects of arginine aspartate and its components on growth hormone, insulin and glucagon secretion in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 267, Issue:1

    Topics: Animals; Arginine; Aspartic Acid; Blood Glucose; Glucagon; Growth Hormone; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains

1984
Synthesis and expression of a gene for the rat glucagon receptor. Replacement of an aspartic acid in the extracellular domain prevents glucagon binding.
    The Journal of biological chemistry, 1994, Nov-18, Volume: 269, Issue:46

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Aspartic Acid; Cells, Cultured; Cloning, Molecular; Enzyme Activation; Genes, Synthetic; Glucagon; Haplorhini; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Receptors, Glucagon; Sequence Homology, Amino Acid; Transfection

1994
Roles of aspartic acid 15 and 21 in glucagon action: receptor anchor and surrogates for aspartic acid 9.
    Biochemistry, 1994, Jun-07, Volume: 33, Issue:22

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aspartic Acid; Drug Design; Glucagon; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Signal Transduction; Structure-Activity Relationship

1994
Glucagon-like peptide-1(7-36)amide induces the release of aspartic acid and glutamine by the ventromedial hypothalamus of the conscious rat.
    Brain research bulletin, 1995, Volume: 38, Issue:5

    Topics: Animals; Aspartic Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glutamine; Hypothalamus, Middle; Male; Microdialysis; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Wistar

1995
Structure-function studies on positions 17, 18, and 21 replacement analogues of glucagon: the importance of charged residues and salt bridges in glucagon biological activity.
    Journal of medicinal chemistry, 1998, Jul-16, Volume: 41, Issue:15

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Cell Membrane; Crystallography, X-Ray; Enzyme Activation; Glucagon; Liver; Male; Molecular Sequence Data; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Glucagon

1998
Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus.
    Neuroreport, 1999, Jun-03, Volume: 10, Issue:8

    Topics: Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glutamic Acid; Glutamine; Hippocampus; Injections, Intraventricular; Male; Neurons; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Stimulation, Chemical; Ventromedial Hypothalamic Nucleus

1999
Studies of hepatic glutamine metabolism in the perfused rat liver with (15)N-labeled glutamine.
    The Journal of biological chemistry, 1999, Oct-08, Volume: 274, Issue:41

    Topics: Ammonia; Animals; Aspartic Acid; Carbamyl Phosphate; Citrulline; Glucagon; Glutamates; Glutaminase; Glutamine; Insulin; Liver; Male; Nitrogen Isotopes; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Urea

1999
The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge.
    FEBS letters, 2002, Oct-23, Volume: 530, Issue:1-3

    Topics: Aspartic Acid; Cell Line; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Mutagenesis, Site-Directed; Peptide Fragments; Protein Precursors; Radioligand Assay; Receptors, Glucagon

2002
Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus.
    The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30

    Topics: Amino Acid Sequence; Aspartic Acid; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Epitopes; Genes, Reporter; Glucagon; Glutamic Acid; Humans; Inhibitory Concentration 50; Models, Biological; Molecular Sequence Data; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Glucagon; Sequence Homology, Amino Acid

2003
Specificity of the cleavage of proteins by dilute acid. I. Release of aspartic acid from insulin, ribonuclease, and glucagon.
    Biochemistry, 1962, Volume: 1

    Topics: Aspartic Acid; Glucagon; Humans; Insulin; Proteins; Ribonucleases

1962
[ON THE HORMONAL REGULATION OF PROTEIN METABOLISM. THE EFFECT ON INSULIN AND GLUCAGON].
    Endokrinologie, 1964, Volume: 46

    Topics: Alanine; Arginine; Aspartic Acid; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glutamates; Glycine; Histidine; Insulin; Leucine; Lysine; Pharmacology; Phenylalanine; Proteins; Threonine; Tyrosine; Valine

1964
The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon.
    International journal of pharmaceutics, 2004, Apr-01, Volume: 273, Issue:1-2

    Topics: Amides; Aspartic Acid; Glucagon; Glutamine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Peptide Fragments

2004
Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:9

    Topics: Animals; Aspartic Acid; Circular Dichroism; Deamination; Deuterium Exchange Measurement; Glucagon; Glutamine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Solutions; Swine; Temperature; Time Factors

2005
Optimization of the native glucagon sequence for medicinal purposes.
    Journal of diabetes science and technology, 2010, Nov-01, Volume: 4, Issue:6

    Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Cell Line; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cyclic AMP; Drug Stability; Genes, Reporter; Glucagon; Glucagon-Like Peptide-1 Receptor; Humans; Hydrogen-Ion Concentration; Hypoglycemia; Isoelectric Point; Molecular Sequence Data; Receptors, Glucagon; Solubility; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Transfection

2010
Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells.
    Molecular and cellular endocrinology, 2011, May-16, Volume: 338, Issue:1-2

    Topics: Alanine; Animals; Aspartic Acid; Cell Membrane; Cells, Cultured; Dicarboxylic Acids; Epinephrine; gamma-Aminobutyric Acid; Glucagon; Glucagon-Secreting Cells; Glucose; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ketoglutaric Acids; Malates; Male; Pyrrolidines; Rats; Rats, Wistar; Transcription, Genetic

2011
In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:2

    Topics: Animals; Aspartic Acid; Carbon Isotopes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Gluconeogenesis; Insulin Resistance; Liver; Magnetic Resonance Spectroscopy; Malates; Male; Mice; Mice, Inbred C57BL; Pyruvate Carboxylase; Pyruvic Acid

2013
Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
    The Biochemical journal, 2015, May-15, Volume: 468, Issue:1

    Topics: Animals; Aspartic Acid; Cell Line; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Glucose; Glycerophosphates; Glycolysis; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Kinetics; Malates; Male; Membrane Transport Proteins; Metabolome; Mice; Mice, Inbred C3H; Mice, Transgenic; Mitochondria

2015
Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.
    Innate immunity, 2017, Volume: 23, Issue:1

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents; Aspartic Acid; Cells, Cultured; Disease Models, Animal; F-Box Proteins; Forkhead Box Protein O1; Gene Expression Regulation; Glucagon; Humans; Hydrocortisone; Lipopolysaccharides; Muscle, Skeletal; Muscular Atrophy; Oncogene Protein v-akt; Paraspinal Muscles; Protein Kinases; Signal Transduction; SKP Cullin F-Box Protein Ligases; Swine; Tripartite Motif Proteins

2017
Effects of three major amino acids found in Japanese broth on glucose metabolism and gastric emptying.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 46

    Topics: Adult; Amino Acids; Animals; Aspartic Acid; Blood Glucose; C-Peptide; Cross-Over Studies; Diet; Female; Fishes; Food, Preserved; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glutamic Acid; Histidine; Humans; Insulin; Japan; Kelp; Male; Oryza

2018