aspartic acid has been researched along with fosfomycin in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Duncan, K; Kempsell, KE; Kim, DH; Lane, WS; Lees, WJ; Walsh, CT | 1 |
| Eschenburg, S; Schönbrunn, E | 1 |
| Amrhein, N; Etezady-Esfarjani, T; Macheroux, P; Samland, AK | 1 |
| Abdul-Latif, FA; Delachaume, C; Eschenburg, S; Fassy, F; Priestman, MA; Schönbrunn, E | 1 |
| Endo, K; Noguchi, K; Ohsawa, K; Ohtaki, A; Sasaki, Y; Takenoya, M; Yajima, S; Yohda, M | 1 |
| Attia, M; Berti, PJ; Gilpin, ME; Jiang, S; Ting, YL | 1 |
| Guo, Y; Han, R; Hu, F; Hu, Z; Li, D; Wang, C; Xin, L; Xu, X | 1 |
7 other study(ies) available for aspartic acid and fosfomycin
| Article | Year |
|---|---|
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.
Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Aspartic Acid; Catalysis; Cell Wall; Cysteine; Drug Resistance, Microbial; Escherichia coli; Fosfomycin; Kinetics; Mutagenesis, Site-Directed; Thermodynamics; Transferases | 1996 |
Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Topics: Alkyl and Aryl Transferases; Aspartic Acid; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Enterobacter cloacae; Fosfomycin; Ligands; Models, Molecular; Phosphates; Protein Conformation; Solvents; Water | 2000 |
Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae.
Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cysteine; Enterobacter cloacae; Enzyme Inhibitors; Fosfomycin; Mutagenesis, Site-Directed; Phosphates; Phosphoenolpyruvate; Recombinant Proteins; Uridine Diphosphate N-Acetylglucosamine | 2001 |
A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).
Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; Crystallography, X-Ray; Drug Resistance, Microbial; Enterobacter cloacae; Enzyme Inhibitors; Fosfomycin; Macromolecular Substances; Models, Molecular; Molecular Structure; Naphthalenesulfonates; Protein Structure, Tertiary | 2005 |
Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding.
Topics: Aldose-Ketose Isomerases; Aspartic Acid; Base Sequence; Catalytic Domain; Crystallography, X-Ray; DNA Primers; DNA, Bacterial; Enzyme Stability; Fosfomycin; Kinetics; Models, Molecular; Multienzyme Complexes; Oxidoreductases; Protein Conformation; Recombinant Proteins; Static Electricity; Thermotoga maritima | 2010 |
Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Biocatalysis; Borrelia burgdorferi; Catalytic Domain; Codon, Initiator; Drug Resistance, Bacterial; Fosfomycin; Hydrogen-Ion Concentration; Kinetics; Lyme Disease; Molecular Sequence Data; Mutation; Salts; Temperature | 2011 |
Asp50Glu mutation in MurA results in fosfomycin resistance in Enterococcus faecium.
Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; Drug Resistance, Bacterial; Enterococcus faecium; Fosfomycin; Glutamic Acid; Mutation | 2022 |