aspartic acid has been researched along with folic acid in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (52.94) | 18.7374 |
| 1990's | 6 (17.65) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Asoklis, K; Asoklis, R | 1 |
| Adams, JA; Benkovic, SJ; Thillet, J | 1 |
| Morrison, JF; Stone, SR | 1 |
| Basappa, SC; Murthy, VS; Vishwanath, P | 1 |
| Ehrlich, D; Sattayasai, J | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Hubert, JC; Wurtz, B | 1 |
| Harris, B; Osmond, CB | 1 |
| Maley, F; Maley, GF | 1 |
| Bartels, H; Gabbe, EE; Heinrich, HC; Kugler, G; Oppitz, KH | 1 |
| Herbert, JA; Teekell, RA; Watts, AB | 1 |
| Bertino, JR; Chabner, BA; McCullough, JL | 1 |
| Besnier, V | 1 |
| Bajusz, E | 1 |
| Goldman, P; Levy, CC | 1 |
| Collingridge, GL; Kehl, SJ; Loo, R; McLennan, H | 1 |
| Ishida, AT | 1 |
| McLennan, H | 1 |
| Brennan, J; Hageboutros, A; Hudes, GR; LaCreta, FP; McAleer, C; Newman, EM; O'Dwyer, PJ; Ozols, RF; Rogatko, A | 1 |
| Barsukov, IL; Basran, J; Casarotto, MG; Roberts, GC | 1 |
| Basran, J; Birdsall, B; Casarotto, MG; Cheung, HT; Feeney, J; Roberts, GC | 1 |
| Biermann, D; Finer-Moore, J; Michelitsch, MD; Nissen, R; Sage, CR; Stout, TJ; Stroud, RM | 1 |
| Badii, R; Basran, J; Casarotto, MG; Roberts, GC; Sze, KH | 1 |
| Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE | 1 |
| Castaldo, P; Cimmino, A; De Santo, NG; di Carlo, E; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
| GREENBERG, NH; MEAD, JA; SCHRECKER, AW; SEEGER, DR; TOMCUFCIK, AS | 1 |
| Ballou, DP; Brinker, DR; Casas, KR; Galloway, LJ; Scannell, SA; Trimmer, EE | 1 |
| Haska, CL; Hou, Z; Matherly, LH; Stapels, SE | 1 |
| Dridi, L; Haimeur, A; Ouellette, M | 1 |
| Fiser, A; Goldman, ID; Min, SH; Russell, L; Shin, DS; Zhao, R | 1 |
| Chen, CS; Juo, SH; Ko, CH; Kuo, YT; Lee, CC; Li, CW; Lin, HF; Liu, GC; Tsai, HY; Yeh, YC; Yen, CF | 1 |
| Bao, Y; Guo, J; Liu, C; Lu, X; Niu, B; Wang, F; Wang, J; Wang, L; Wu, L; Xie, H; Zhang, T; Zhao, H; Zou, J | 1 |
| Cao, F; Li, X; Li, Z; Liu, C; Wang, M; Wang, X; Xie, Y; Yao, X | 1 |
1 trial(s) available for aspartic acid and folic acid
| Article | Year |
|---|---|
Phase I study of phosphonacetyl-L-aspartate, 5-fluorouracil, and leucovorin in patients with advanced cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Digestive System; Drug Synergism; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Neutropenia; Phosphonoacetic Acid; Proportional Hazards Models; Pyrimidines; Remission Induction; Risk Factors; Thymidylate Synthase | 1995 |
33 other study(ies) available for aspartic acid and folic acid
| Article | Year |
|---|---|
[Treatment of vitamin B 12 deficiency].
Topics: Arginine; Aspartic Acid; Choline; Drug Combinations; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intramuscular; Malates; Phosphorylcholine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 1977 |
The kinetic mechanism of wild-type and mutant mouse dihydrofolate reductases.
Topics: Animals; Aspartic Acid; Binding Sites; Escherichia coli; Folic Acid; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Mice; Mutation; Tetrahydrofolate Dehydrogenase | 1990 |
Mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli: pH and deuterium isotope effects with NADPH as the variable substrate.
Topics: Aspartic Acid; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NADP; Solvents; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1988 |
Mechanism of counteraction of aflatoxin toxicity by thymine and folic acid in Bacillus megaterium.
Topics: Aflatoxin B1; Aflatoxins; Aminopterin; Aspartic Acid; Bacillus megaterium; DNA, Bacterial; Drug Synergism; Folic Acid; Orotic Acid; Thymine; Uracil; Uridine Monophosphate | 1986 |
Folic acid protects chick retinal neurons against the neurotoxic action of excitatory amino acids.
Topics: Animals; Aspartic Acid; Chickens; Dose-Response Relationship, Drug; Folic Acid; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acids; Quisqualic Acid; Retina | 1987 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
[Research on the aspartase of Pseudomonas fluorescens. 3. Role of folic acid in the stimulation of aspartic activity].
Topics: Aspartic Acid; Enzyme Induction; Folic Acid; Lyases; Pseudomonas | 1966 |
Photorespiration during C 4 photosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Aldehyde-Lyases; Aspartic Acid; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Electrophoresis; Folic Acid; Fructose; Glycerophosphates; Glycine; Glycolates; Glyoxylates; Hexosephosphates; Ligases; Malates; Oxidoreductases; Pentosephosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Photosynthesis; Plants; Pyruvates; Ribose; Serine; Sulfites; Transferases | 1971 |
The apparent induction of thymidylate synthetase by amethopterin.
Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Methotrexate; Methyltransferases; Neoplasms, Experimental; Quinazolines; Rats; Thymine Nucleotides; Uracil Nucleotides | 1971 |
Effects of so-called iron absorption-promoting additives in humans as measured with the 59 Fe-absorption whole-body retention test. Intraindividual comparison of succinate, dioctylsulfosuccinate-, fumarate-, aspartate-, ascorbate- and folate-effects on
Topics: Administration, Oral; Anemia, Hypochromic; Ascorbic Acid; Aspartic Acid; Drug Combinations; Evaluation Studies as Topic; Folic Acid; Fumarates; Hemoglobins; Humans; Intestinal Absorption; Iron; Iron Isotopes; Octanols; Succinates; Whole-Body Counting | 1972 |
Effect of amino acids on liver RNA synthesis in the chick.
Topics: Amino Acids; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Chickens; Diet; Folic Acid; Glutamine; Glycine; Liver; Protein Biosynthesis; RNA; Tritium; Tryptophan; Uridine | 1972 |
Purification and properties of carboxypeptidase G 1 .
Topics: Ammonium Sulfate; Aspartic Acid; Carboxypeptidases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Disc; Enzyme Activation; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Hydrolysis; Isoelectric Focusing; Methotrexate; Molecular Weight; Pseudomonas; Zinc | 1971 |
[Influence of a vitamin mixture on growth and free amino acid concentration of a marine diatome].
Topics: Amino Acids; Aminobenzoates; Aspartic Acid; Biotin; Culture Media; Folic Acid; Inositol; Nicotinic Acids; Pantothenic Acid; Plankton; Thiamine; Thymine; Vitamin B 12; Vitamins | 1969 |
Enhanced healing of myocardial lesions and prevention of congestive heart failure. Experimental studies on the therapeutic effect of K-salts, alone and in combination with glucose and insulin, in a hereditary cardiomyopathy.
Topics: Animals; Aspartic Acid; Cardiomyopathies; Chronic Disease; Citrates; Connective Tissue; Cricetinae; Drug Synergism; Female; Fibroblasts; Folic Acid; Gluconates; Glucose; Heart Failure; Insulin; Magnesium; Male; Myocardium; Orotic Acid; Potassium; Potassium Chloride; Protein Biosynthesis; Salts; Sodium; Stimulation, Chemical | 1969 |
The enzymatic hydrolysis of folate analogues.
Topics: Aspartic Acid; Carboxypeptidases; Folic Acid; Glutamates; Methods; Methotrexate; Peptide Hydrolases; Pseudomonas; Pteridines; Soil Microbiology; Spectrophotometry | 1968 |
Effects of kainic and other amino acids on synaptic excitation in rat hippocampal slices: 1. Extracellular analysis.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Evoked Potentials; Folic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Rats | 1983 |
Responses of solitary retinal horizontal cells to L-glutamate and kainic acid are antagonized by D-aspartate.
Topics: Animals; Aspartic Acid; Cyprinidae; Excitatory Amino Acid Antagonists; Folic Acid; Glutamates; Glutamic Acid; Goldfish; Interneurons; Kainic Acid; Pyrrolidines; Retina; Stereoisomerism | 1984 |
Methyltetrahydrofolate as an antagonist of excitatory amino acids on spinal neurones.
Topics: Amino Acids; Animals; Aspartic Acid; Folic Acid; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrahydrofolates | 1982 |
Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Oxidation-Reduction; Point Mutation; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1995 |
The influence of aspartate 26 on the tautomeric forms of folate bound to Lactobacillus casei dihydrofolate reductase.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; NADP; Point Mutation; Recombinant Proteins; Stereoisomerism; Tetrahydrofolate Dehydrogenase | 1997 |
D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine.
Topics: Asparagine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Escherichia coli; Fluorodeoxyuridylate; Folic Acid; Hydrogen Bonding; Imidazoles; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Quinazolines; Substrate Specificity; Tetrahydrofolates; Thymidylate Synthase | 1998 |
Direct measurement of the pKa of aspartic acid 26 in Lactobacillus casei dihydrofolate reductase: implications for the catalytic mechanism.
Topics: Apoenzymes; Aspartic Acid; Catalysis; Folic Acid; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Macromolecular Substances; NAD; Tetrahydrofolate Dehydrogenase | 1999 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
THE PHARMACOLOGICAL AND BIOCHEMICAL ACTIVITY OF 4-AMINO-4-DEOXY-10-METHYLPTEROYLASPARTIC ACID.
Topics: Adenine; Amino Acids; Animals; Aspartic Acid; Enzyme Inhibitors; Folic Acid; Formates; Kinetics; Leukemia L1210; Liver; Methotrexate; Mice; Oxidoreductases; Pharmacology; Research | 1965 |
Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Asparagine; Aspartic Acid; Catalysis; Cold Temperature; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Folic Acid; Imines; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry; Substrate Specificity; Thermodynamics | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Structure-function analysis of the highly conserved charged residues of the membrane protein FT1, the main folic acid transporter of the protozoan parasite Leishmania.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Aspartic Acid; Conserved Sequence; Folic Acid; Glutamic Acid; Leishmania; Membrane Transport Proteins; Molecular Sequence Data; Protein Transport; Protozoan Proteins | 2010 |
Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption.
Topics: Amino Acid Substitution; Aspartic Acid; Child; DNA Mutational Analysis; Folic Acid; Homozygote; Humans; Infant, Newborn; Malabsorption Syndromes; Mutation, Missense; Pakistan; Protein Stability; Proton-Coupled Folate Transporter | 2010 |
Brain biochemical correlates of the plasma homocysteine level: a proton magnetic resonance spectroscopy study in the elderly subjects.
Topics: Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Cobamides; Creatine; Female; Folic Acid; Frontal Lobe; Hippocampus; Homocysteine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sex Characteristics | 2011 |
Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population.
Topics: Adult; Anencephaly; Asian People; Aspartic Acid; Case-Control Studies; China; Dipeptides; Encephalocele; Female; Folic Acid; Gene Frequency; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Neural Tube Defects; Polymorphism, Genetic; Risk Factors; Spinal Dysraphism; Young Adult | 2012 |
Folic Acid/Peptides Modified PLGA-PEI-PEG Polymeric Vectors as Efficient Gene Delivery Vehicles: Synthesis, Characterization and Their Biological Performance.
Topics: Aspartic Acid; Biocompatible Materials; DNA; Folic Acid; Gene Transfer Techniques; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Laminin; Microscopy, Electron, Scanning; Nanocomposites; Particle Size; Peptide Fragments; Peptides; Polyethylene Glycols; Polyethyleneimine; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectroscopy, Fourier Transform Infrared; Transfection | 2021 |