Page last updated: 2024-08-17

aspartic acid and epidermal growth factor

aspartic acid has been researched along with epidermal growth factor in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's14 (46.67)18.2507
2000's5 (16.67)29.6817
2010's1 (3.33)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Campion, SR; Niyogi, SK; Tadaki, DK1
Iwanaga, S; Nishimura, H; Walz, DA; Yamashita, S; Zeng, Z1
Gomi, K; Hayashi, T; Honda, G; Kondo, S; Suzuki, K; Yamamoto, S; Zushi, M1
Stenflo, J1
Borissenko, M; Calderón, M; Clarke, S; George-Nascimento, C; Kuo, J; Lowenson, J; Medina-Selby, A; Randolph, A1
Lin, SW; Smith, KJ; Stafford, DW; Welsch, D1
Bourdon, P; Landes, G; Ohlin, AK; Oppenheimer, C; Stenflo, J; Wydro, R1
Chandramouli, N; Holme, E; Huang, LH; Lindstedt, S; Merrifield, RB; Stenflo, J; Tam, JP1
Leysen, JE; Pauwels, PJ; van Assouw, HP1
Drakenberg, T; Linse, S; Ohlin, AK; Persson, E; Selander, M; Stenflo, J1
Bennett, CD; Friedman, PA; Musson, DG; Przysiecki, CT; Ramjit, HG; Staggers, JE; Stern, AM1
Ohlin, AK; Owen, WG; Schneider, WJ; Stenflo, J1
Brownlee, GG; Esnouf, MP; Handford, PA; Jones, IM; Rees, DJ; Smith, KJ; Walter, SJ1
Aberth, W; Brown, CF; DiAugustine, RP; Ferrua, CM; Gibson, BW; Kelly, M; Tomooka, Y; Walker, M1
Folkman, J; Igarashi, K; Nakata, M; Sasada, R; Shing, Y; Shintani, A; Watanabe, T1
Campbell, ID; Dahlqvist, I; Drakenberg, T; Handford, P; Mayhew, M; Persson, E; Robin, M; Stenflo, J; Sunnerhagen, MS; Tilley, JW1
Barford, D; Flint, AJ; Tiganis, T; Tonks, NK1
Nielsen, LS; Olsen, OH; Ostergaard, A; Persson, E1
Drakenberg, T; Finn, BE; Forsén, S; Gippert, GP; Muranyi, A; Stenflo, J1
Babcock, D; Francke, U; Gasner, C; Maslen, C1
Nielsen, LS; Persson, E1
Cuthbertson, A; Fischer, PM; Husbyn, M; Orning, L1
Cuthbertson, A; Husbyn, M1
Grammatopoulos, TN; Miranda, M; Sorkin, A; Sorkina, T; Zawada, WM1
Menard, RE; Qian, Z; Rosner, MR; Schade, GR; Trakul, N1
Ravid, S; Rosenberg, M1
Furuchi, T; Homma, H; Katane, M; Kosugi, S; Sekine, M; Shirasawa, T1
Baars, MJ; Bijlsma, EK; Breuning, MH; Giltay, JC; Hamel, BC; Hilhorst-Hofstee, Y; Kerstjens-Frederikse, WS; Pals, G; Rijlaarsdam, ME; Schäbitz, HJ; Scholte, AJ; Swart-van den Berg, M; van der Schoot-van Velzen, I; Versteegh, MI1
Brewitz, L; Onisko, BC; Schofield, CJ1
Chen, F; Chen, J; Deng, J; Luo, L; Tang, J; Wang, H; Wang, Y; Wu, Z; Xu, L; Zhou, Q1

Reviews

1 review(s) available for aspartic acid and epidermal growth factor

ArticleYear
Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors.
    Blood, 1991, Oct-01, Volume: 78, Issue:7

    Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blood Coagulation Factors; Calcium; Epidermal Growth Factor; Humans; Molecular Sequence Data; Structure-Activity Relationship; Vitamin K

1991

Other Studies

29 other study(ies) available for aspartic acid and epidermal growth factor

ArticleYear
Evaluation of the role of electrostatic residues in human epidermal growth factor by site-directed mutagenesis and chemical modification.
    Journal of cellular biochemistry, 1992, Volume: 50, Issue:1

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Electrochemistry; Epidermal Growth Factor; ErbB Receptors; Glutamates; Glutamic Acid; Glutamine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation

1992
Evidence for the existence of O-linked sugar chains consisting of glucose and xylose in bovine thrombospondin.
    Journal of biochemistry, 1992, Volume: 111, Issue:4

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Carbohydrate Metabolism; Carbohydrate Sequence; Carbohydrates; Cattle; Chickens; Epidermal Growth Factor; Glucose; Humans; Molecular Sequence Data; Molecular Weight; Oligosaccharides; Oxidation-Reduction; Peptide Fragments; Platelet Membrane Glycoproteins; Thrombospondins; Xylose

1992
Aspartic acid 349 in the fourth epidermal growth factor-like structure of human thrombomodulin plays a role in its Ca(2+)-mediated binding to protein C.
    The Journal of biological chemistry, 1991, Oct-25, Volume: 266, Issue:30

    Topics: Amino Acid Sequence; Aspartic Acid; Blotting, Western; Calcium; Catalysis; Cell Line; DNA; Epidermal Growth Factor; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein C; Receptors, Cell Surface; Receptors, Thrombin; Sequence Alignment; Thrombin

1991
Replacement of a labile aspartyl residue increases the stability of human epidermal growth factor.
    Biochemistry, 1990, Oct-16, Volume: 29, Issue:41

    Topics: Amino Acid Sequence; Aspartic Acid; Cells, Cultured; Chymotrypsin; DNA Replication; Drug Stability; Epidermal Growth Factor; Humans; Methylation; Molecular Sequence Data; Oligopeptides; Peptide Mapping; Recombinant Proteins; Thermolysin; Thymidine

1990
Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cells.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Blood Coagulation; Calcium; Cell Line; Epidermal Growth Factor; Factor IX; Factor VIIa; Factor X; Factor XIa; Gene Expression; Humans; Hydroxylation; Mice; Molecular Sequence Data; Recombinant Proteins; Thromboplastin

1990
Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity.
    The Journal of biological chemistry, 1988, Dec-15, Volume: 263, Issue:35

    Topics: Antibodies, Monoclonal; Aspartic Acid; Base Sequence; Calcium; Epidermal Growth Factor; Epitopes; Humans; Kinetics; Molecular Sequence Data; Protein C

1988
Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:2

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Carbon Dioxide; Epidermal Growth Factor; Factor IX; Humans; Hydroxylation; Ketoglutaric Acids; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; Protein Conformation; Protein Precursors; Rats

1989
Attenuation of neurotoxicity following anoxia or glutamate receptor activation in EGF- and hippocampal extract-treated neuronal cultures.
    Cellular signalling, 1989, Volume: 1, Issue:1

    Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Growth Substances; Hippocampus; Hypoxia, Brain; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Oxygen; Potassium Cyanide; Rats; Receptors, Adrenergic, beta; Receptors, Glutamate; Receptors, Neurotransmitter

1989
Calcium binding to the isolated beta-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X.
    The Journal of biological chemistry, 1989, Oct-05, Volume: 264, Issue:28

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Cattle; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor X; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Protein Binding; Protein Conformation; Trypsin

1989
Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:22

    Topics: Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Complement Activating Enzymes; Complement C1; Complement C1r; Complement C1s; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Humans; Mucoproteins; Protein Processing, Post-Translational; Sequence Homology, Nucleic Acid; Uromodulin

1987
beta-Hydroxyaspartic acid or beta-hydroxyasparagine in bovine low density lipoprotein receptor and in bovine thrombomodulin.
    The Journal of biological chemistry, 1988, Jan-05, Volume: 263, Issue:1

    Topics: Adrenal Glands; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cattle; Epidermal Growth Factor; Molecular Sequence Data; Receptors, Cell Surface; Receptors, LDL; Receptors, Thrombin; Sequence Homology, Nucleic Acid

1988
The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.
    The EMBO journal, 1988, Volume: 7, Issue:7

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Carboxylic Acids; Codon; Dogs; Epidermal Growth Factor; Factor IX; Factor IXa; Humans; Macromolecular Substances; Molecular Sequence Data; Mutation; Protein Processing, Post-Translational; Serine Endopeptidases

1988
Evidence for isoaspartyl (deamidated) forms of mouse epidermal growth factor.
    Analytical biochemistry, 1987, Volume: 165, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Chromatography, Gel; Chromatography, High Pressure Liquid; Epidermal Growth Factor; Genetic Variation; Mice; Submandibular Gland

1987
Recombinant human betacellulin. Molecular structure, biological activities, and receptor interaction.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Aspartic Acid; Betacellulin; Cell Division; Cell Line; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Culture Media, Conditioned; Epidermal Growth Factor; ErbB Receptors; Female; Glycosylation; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine

1994
The effect of aspartate hydroxylation on calcium binding to epidermal growth factor-like modules in coagulation factors IX and X.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Amino Acid Sequence; Aspartic Acid; Calcium; Calcium-Binding Proteins; Epidermal Growth Factor; Factor IX; Factor X; Humans; Hydroxylation; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Structure, Tertiary; Structure-Activity Relationship; Tyrosine

1993
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-04, Volume: 94, Issue:5

    Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Blotting, Western; Cells, Cultured; COS Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Microscopy, Fluorescence; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Point Mutation; Protein Binding; Protein Tyrosine Phosphatases; Substrate Specificity; Transfection

1997
Ca2+ binding to the first epidermal growth factor-like domain of factor VIIa increases amidolytic activity and tissue factor affinity.
    The Journal of biological chemistry, 1997, Aug-08, Volume: 272, Issue:32

    Topics: Aspartic Acid; Binding Sites; Calcium; Chromatography, Affinity; Epidermal Growth Factor; Factor VIIa; Factor X; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Thromboplastin

1997
Solution structure of the N-terminal EGF-like domain from human factor VII.
    Biochemistry, 1998, Jul-28, Volume: 37, Issue:30

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography, X-Ray; Epidermal Growth Factor; Factor VII; Humans; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solutions

1998
A single mutation that results in an Asp to His substitution and partial exon skipping in a family with congenital contractural arachnodactyly.
    Human genetics, 1998, Volume: 103, Issue:1

    Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Epidermal Growth Factor; Exons; Female; Fibrillin-2; Fibrillins; Histidine; Humans; Male; Marfan Syndrome; Microfilament Proteins; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Transcription, Genetic

1998
Ca2+ in the first epidermal growth factor-like domain of activated factor VII.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9 Suppl 1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Calcium; Epidermal Growth Factor; Factor VIIa; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary

1998
Linear analogues derived from the first EGF-like domain of human blood coagulation factor VII: enhanced inhibition of FVIIa/TF complex activity by backbone modification through aspartimide formation.
    Journal of peptide science : an official publication of the European Peptide Society, 1999, Volume: 5, Issue:7

    Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Epidermal Growth Factor; Factor VII; Humans; Molecular Sequence Data; Structure-Activity Relationship

1999
A novel approach to the synthesis of EGF-like domains: a method for the one-pot regioselective formation of the three disulfide bonds of a human blood coagulation factor VII EGF-1 analogue.
    The journal of peptide research : official journal of the American Peptide Society, 2002, Volume: 60, Issue:2

    Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; Epidermal Growth Factor; Factor VII; Humans; Molecular Sequence Data; Peptides; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2002
Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.
    The Journal of biological chemistry, 2004, Jul-16, Volume: 279, Issue:29

    Topics: Alanine; Amino Acid Sequence; Animals; Aorta; Aspartic Acid; Bacterial Proteins; Biotinylation; Cell Membrane; Cells, Cultured; Dopamine Plasma Membrane Transport Proteins; Endoplasmic Reticulum; Endothelium, Vascular; Epidermal Growth Factor; Fluorescence Resonance Energy Transfer; Glycine; Luminescent Proteins; Lysine; Membrane Glycoproteins; Membrane Transport Proteins; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Nerve Tissue Proteins; Neurons; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Swine; Transfection

2004
Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation.
    The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26

    Topics: Animals; Aspartic Acid; Cell Line; Cell Membrane; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Growth Substances; Hippocampus; Humans; Immunoprecipitation; MAP Kinase Signaling System; Models, Biological; Mutation; Neurons; Phosphatidylethanolamine Binding Protein; Phosphorylation; Protein Binding; Protein Isoforms; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Rats; RNA; RNA, Small Interfering; Serine; Signal Transduction; Time Factors; Tyrosine

2005
Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly.
    Molecular biology of the cell, 2006, Volume: 17, Issue:3

    Topics: Actomyosin; Amino Acid Sequence; Animals; Aspartic Acid; Cell Polarity; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytoskeleton; Epidermal Growth Factor; Fibroblasts; Gene Expression; Humans; Mice; Models, Biological; Molecular Sequence Data; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Peptide Mapping; Phosphorylation; Protein Kinase C; Protein Transport; Recombinant Fusion Proteins

2006
Suppression of protein l-isoaspartyl (d-aspartyl) methyltransferase results in hyperactivation of EGF-stimulated MEK-ERK signaling in cultured mammalian cells.
    Biochemical and biophysical research communications, 2008, Jun-20, Volume: 371, Issue:1

    Topics: Aspartic Acid; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Humans; Isomerism; MAP Kinase Kinase Kinases; Phosphorylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Signal Transduction

2008
The clinical spectrum of missense mutations of the first aspartic acid of cbEGF-like domains in fibrillin-1 including a recessive family.
    Human mutation, 2010, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Child; Epidermal Growth Factor; Family; Female; Fibrillin-1; Fibrillins; Genes, Recessive; Humans; Infant; Male; Microfilament Proteins; Middle Aged; Models, Molecular; Mutation, Missense; Pedigree; Protein Structure, Tertiary; Structure-Activity Relationship; Young Adult

2010
Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:8

    Topics: Antigens, Ly; Asparagine; Aspartic Acid; Consensus Sequence; Epidermal Growth Factor; Humans; Hydroxylation; Proteomics

2022
Aspartic acid and epidermal growth factor modified decellularized rabbit conjunctiva for conjunctival reconstruction.
    Biomaterials advances, 2022, Volume: 143

    Topics: Animals; Aspartic Acid; Cells, Cultured; Collagen; Conjunctiva; Epidermal Growth Factor; Rabbits

2022