Page last updated: 2024-08-17

aspartic acid and dithiothreitol

aspartic acid has been researched along with dithiothreitol in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199011 (32.35)18.7374
1990's9 (26.47)18.2507
2000's10 (29.41)29.6817
2010's4 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cooney, DA; Cragoe, EJ; Homan, ER; Jayaram, HN; King, WM; Milman, HA1
Feldman, J; Takahashi, M; Wright, JK1
Aksamit, RR; Howlett, BJ; Koshland, DE1
Kawata, T; Kinouchi, T; Takumi, K1
Casanova, J; Johnson, AB; Kaul, R; Matalon, R; Tang, P1
Inoue, S; Kataoka, K; Okano, T; Sakurai, Y; Yokoyama, M1
Aizenman, E; Lipton, SA; Loring, RH1
Hamanaka, K; Ono, B; Shinoda, S; Suemoto, Y; Yamamoto, S1
Janin, J1
Botes, DP1
Lamont, HC; Staudenbauer, WL; Strominger, JL1
Anderson, DM; Hendrie, A1
Aschner, M; Fehm, MN; Mullaney, KJ; Vitarella, D; Wagoner, DE1
Albrecht, J; Aschner, M; Kimelberg, HK; Mullaney, KJ; Vitarella, D1
Gomi, S; Imae, Y; Iwama, T; Lee, L1
Denissova, L; Goldfarb, A; Heumann, H; Kashlev, M; Kozlov, M; Markovtsov, V; Martin, E; Mustaev, A; Nikiforov, V; Zaychikov, E1
Ikuta, K; Kameoka, M; Kimura, T; Okada, Y; Tobiume, M1
Fonnum, F; Mathisen, GA; Paulsen, RE1
LeMaster, DM; Springer, PA; Unkefer, CJ1
Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA1
Hada, J; Hayashi, Y; Jiang, MH; Kaku, T; Morimoto, K1
Allen, JW; Aschner, M; Mutkus, LA1
Geczy, CL; Raftery, MJ; Valenzuela, SM; Yang, Z1
Gross, AK; Oprian, DD; Xie, G1
Jackson, RM; Powell, CS1
Bartholomew, LA; Gimi, K; Senior, AE; Tombline, G; Tyndall, GA; Urbatsch, IL1
Eapen, A; Sharma, A; Subbarao, SK1
Chait, BT; Fushitani, K; Gorr, TA; Kao, WY; Knapp, JE; Qin, J; Riggs, AF; Riggs, CK; Smith, SS1
Betté, S; Castagna, M; Mandela, PG; Mari, SA; Peres, A; Rudnick, G; Sacchi, VF; Santacroce, M; Soragna, A1
Ahmad, MF; Ramakrishna, T; Raman, B; Rao, ChM1
Lukesh, JC; Palte, MJ; Raines, RT1
Gibney, PA; Morano, KA; Wang, Y; West, JD1
Qu, S; Zhang, X; Zhang, Y1
Qu, S; Rong, X; Zhang, X1

Other Studies

34 other study(ies) available for aspartic acid and dithiothreitol

ArticleYear
Ethacrynic acid--an inhibitor of L-asparagine synthetase.
    Biochemical pharmacology, 1975, Oct-01, Volume: 24, Issue:19

    Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Asparaginase; Aspartate-Ammonia Ligase; Aspartic Acid; Cell Line; Dithiothreitol; Dogs; Escherichia coli; Ethacrynic Acid; Female; Glutamine; In Vitro Techniques; Leukemia, Experimental; Ligases; Magnesium; Male; Mice; Mice, Inbred Strains; Pancreas; Rodentia; Time Factors

1975
Cobalt(III) affinity-labeled aspartokinase. Formation of substrate and inhibitor adducts.
    Biochemistry, 1976, Aug-24, Volume: 15, Issue:17

    Topics: Adenosine Triphosphate; Affinity Labels; Aspartate Kinase; Aspartic Acid; Aspartokinase Homoserine Dehydrogenase; Binding Sites; Borohydrides; Cobalt; Dithiothreitol; Escherichia coli; Hydrogen Peroxide; Mercaptoethanol; Multienzyme Complexes; Phosphotransferases; Protein Binding; Threonine

1976
Soluble and membrane-bound aspartate-binding activities in Salmonella typhimurium.
    Journal of bacteriology, 1975, Volume: 123, Issue:3

    Topics: Aspartic Acid; Bacterial Proteins; Binding, Competitive; Biological Transport, Active; Cell Membrane; Chemotaxis; Cysteic Acid; Dithiothreitol; Edetic Acid; Glutamates; Hydrogen-Ion Concentration; Molecular Weight; Propionates; Receptors, Drug; Salmonella typhimurium; Structure-Activity Relationship

1975
Isolation and partial characterization of exosporium from spores of a highly sporogenic mutant of Clostridium botulinum type A.
    Microbiology and immunology, 1979, Volume: 23, Issue:6

    Topics: Amino Acids; Amino Sugars; Aspartic Acid; Clostridium botulinum; Dithiothreitol; Guanidines; Mercaptoethanol; Peptide Hydrolases; Spores, Bacterial

1979
Purification, characterization, and localization of aspartoacylase from bovine brain.
    Journal of neurochemistry, 1991, Volume: 56, Issue:1

    Topics: Amidohydrolases; Animals; Aspartic Acid; Brain; Cations, Divalent; Cattle; Detergents; Dipeptides; Dithiothreitol; Enzyme Stability; Kinetics; Mercaptoethanol; Molecular Weight; Tissue Distribution

1991
Stabilization of disulfide linkage in drug-polymer-immunoglobulin conjugate by microenvironmental control.
    Biochemical and biophysical research communications, 1989, Nov-15, Volume: 164, Issue:3

    Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Disulfides; Dithiothreitol; Doxorubicin; Drug Stability; Immunoglobulin G; Polyethylene Glycols; Polymers; Protein Binding; Spectrometry, Fluorescence

1989
Selective modulation of NMDA responses by reduction and oxidation.
    Neuron, 1989, Volume: 2, Issue:3

    Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Chickens; Dithionitrobenzoic Acid; Dithiothreitol; Fetus; Membrane Potentials; N-Methylaspartate; Neurons; Oxidation-Reduction; Rats; Retina; Retinal Ganglion Cells; Zinc

1989
Evidence for the presence of a novel biosynthetic pathway for norspermidine in Vibrio.
    Canadian journal of microbiology, 1986, Volume: 32, Issue:2

    Topics: Aspartic Acid; Diamines; Dithiothreitol; Gas Chromatography-Mass Spectrometry; NADP; Putrescine; Pyridoxal Phosphate; Schiff Bases; Spermidine; Vibrio; Vibrio parahaemolyticus

1986
Crystallization of E. coli aspartokinase I-homoserine dehydrogenase I.
    FEBS letters, 1974, Sep-01, Volume: 45, Issue:1

    Topics: Alcohol Oxidoreductases; Ammonium Sulfate; Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallization; Dithiothreitol; Escherichia coli; Homoserine; Macromolecular Substances; Molecular Weight; NADP; Oxidation-Reduction; Phosphotransferases; Protein Binding; Protein Conformation; Temperature; Threonine; X-Ray Diffraction

1974
Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin alpha.
    Biochimica et biophysica acta, 1974, Aug-08, Volume: 359, Issue:2

    Topics: Animals; Aspartic Acid; Binding Sites; Biological Assay; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Disulfides; Dithiothreitol; Electrophoresis, Paper; Glycine; Immunodiffusion; Iodoacetates; Lethal Dose 50; Mice; Peptide Fragments; Phenylalanine; Protein Binding; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Toxins, Biological; Tryptophan; Venoms

1974
Partial purification and characterization of an aspartate racemase from Streptococcus faecalis.
    The Journal of biological chemistry, 1972, Aug-25, Volume: 247, Issue:16

    Topics: Alanine; Aluminum Hydroxide; Amino Acid Isomerases; Ammonium Sulfate; Aspartic Acid; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dithiothreitol; Drug Stability; Enterococcus faecalis; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Isomerases; Kinetics; Ligases; Manganese; Structure-Activity Relationship; Sulfhydryl Reagents

1972
The proteinaceous, gum polysaccharide from Azadirachta indica A. Juss.
    Carbohydrate research, 1971, Volume: 20, Issue:2

    Topics: Amino Acids; Amino Sugars; Aspartic Acid; Chromatography, Gel; Dithiothreitol; Plant Proteins; Polysaccharides; Resins, Plant; Serine; Threonine; Trees

1971
Astrocytes as potential modulators of mercuric chloride neurotoxicity.
    Cellular and molecular neurobiology, 1994, Volume: 14, Issue:6

    Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biological Transport; Brain; Calcium Channels; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Glutamic Acid; Glutathione; Kinetics; Mercuric Chloride; Nimodipine; Rats; Rats, Sprague-Dawley; Time Factors

1994
Stimulation of D-aspartate efflux by mercuric chloride from rat primary astrocyte cultures.
    Brain research. Developmental brain research, 1993, Oct-15, Volume: 75, Issue:2

    Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Cell Membrane; Cells, Cultured; Chromates; Chromium Radioisotopes; Dithiothreitol; Glutathione; Mercuric Chloride; Rats; Rats, Sprague-Dawley; Sodium Compounds; Stimulation, Chemical; Sulfhydryl Compounds

1993
Inhibition of aspartate chemotaxis of Escherichia coli by site-directed sulfhydryl modification of the receptor.
    Journal of biochemistry, 1993, Volume: 113, Issue:2

    Topics: Aspartic Acid; Bacterial Proteins; Base Sequence; Chemoreceptor Cells; Chemotaxis; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Escherichia coli; Escherichia coli Proteins; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Receptors, Cell Surface; Sulfhydryl Compounds; Threonine

1993
Mapping of catalytic residues in the RNA polymerase active center.
    Science (New York, N.Y.), 1996, Jul-05, Volume: 273, Issue:5271

    Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Dithiothreitol; DNA; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ferrous Compounds; Hydroxyl Radical; Magnesium; Molecular Sequence Data; Mutagenesis; Promoter Regions, Genetic

1996
Intracellular glutathione as a possible direct blocker of HIV type 1 reverse transcription.
    AIDS research and human retroviruses, 1996, Nov-20, Volume: 12, Issue:17

    Topics: Acetylcysteine; Aspartic Acid; Cysteine; Dithiothreitol; DNA, Viral; Glutathione; HIV Reverse Transcriptase; HIV-1; Humans; Transcription, Genetic; Tumor Cells, Cultured

1996
Contributing mechanisms for cysteine excitotoxicity in cultured cerebellar granule cells.
    Neurochemical research, 1996, Volume: 21, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Bicarbonates; Biological Transport; Cell Death; Cells, Cultured; Cerebellum; Culture Media; Cysteine; Dithiothreitol; Dizocilpine Maleate; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Neurons; Neurotoxins; Rats; Rats, Wistar

1996
The role of the buried aspartate of Escherichia coli thioredoxin in the activation of the mixed disulfide intermediate.
    The Journal of biological chemistry, 1997, Nov-28, Volume: 272, Issue:48

    Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Cysteine; Disulfides; Dithiothreitol; Escherichia coli; Kinetics; Oxidation-Reduction; Protein Disulfide-Isomerases; Thioredoxins

1997
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
    Free radical research, 1998, Volume: 28, Issue:2

    Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin

1998
Sodium nitroprusside-induced seizures and adenosine release in rat hippocampus.
    European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3

    Topics: Adenosine; Animals; Aspartic Acid; Chelating Agents; Dithiothreitol; Ditiocarb; Hippocampus; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Seizures; Vasodilator Agents

2001
Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase.
    Brain research, 2001, May-25, Volume: 902, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antioxidants; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Catalase; Cattle; Cells, Cultured; Chromans; Cyclic N-Oxides; Dinitrobenzenes; Dithiothreitol; Hydrogen Peroxide; Methylmercury Compounds; Nerve Tissue Proteins; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reducing Agents; RNA, Messenger; Spin Labels

2001
Novel intra- and inter-molecular sulfinamide bonds in S100A8 produced by hypochlorite oxidation.
    The Journal of biological chemistry, 2001, Sep-07, Volume: 276, Issue:36

    Topics: Amino Acid Sequence; Antigens, Differentiation; Aspartic Acid; Binding Sites; Calcium-Binding Proteins; Calgranulin A; Chromatography, High Pressure Liquid; Cyclohexanones; Cysteine; Dimerization; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hypochlorous Acid; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neutrophils; Oxygen; Peptides; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfenic Acids; Sulfur; Tetradecanoylphorbol Acetate; Time Factors

2001
An opsin mutant with increased thermal stability.
    Biochemistry, 2003, Feb-25, Volume: 42, Issue:7

    Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cattle; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dithiothreitol; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Thermodynamics; Transducin; Transfection

2003
Mitochondrial complex I, aconitase, and succinate dehydrogenase during hypoxia-reoxygenation: modulation of enzyme activities by MnSOD.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:1

    Topics: Aconitate Hydratase; Adenocarcinoma, Papillary; Adenoviridae; Aspartic Acid; Dithiothreitol; Electron Transport Complex I; Enzyme Activation; Epithelial Cells; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Ketoglutaric Acids; Light; Mitochondria; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxidative Stress; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Respiratory Mucosa; Rhodamines; Succinate Dehydrogenase; Succinic Acid; Superoxide Dismutase; Transfection; Tumor Cells, Cultured

2003
Properties of P-glycoprotein with mutations in the "catalytic carboxylate" glutamate residues.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carboxylic Acids; Catalysis; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutamic Acid; Hydrolysis; Kinetics; Lipid Metabolism; Lysine; Mice; Models, Chemical; Mutation; Pichia; Protein Conformation; Protein Structure, Tertiary; Time Factors; Vanadates

2004
Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition.
    Journal of biochemistry, 2004, Volume: 136, Issue:3

    Topics: Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Catalase; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Gelatin; Glutamate Dehydrogenase (NADP+); Glutathione; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Malaria, Vivax; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Pepsin A; Pepstatins; Plasmodium; Plasmodium vivax; Protease Inhibitors; Reactive Nitrogen Species; S-Nitrosoglutathione; Time Factors; Up-Regulation

2004
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
    Proteins, 2006, Apr-01, Volume: 63, Issue:1

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase

2006
Interaction between lysine 102 and aspartate 338 in the insect amino acid cotransporter KAAT1.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:4

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Binding Sites; Biological Transport; Cross-Linking Reagents; Cysteine; Dithiothreitol; Female; Insect Proteins; Kinetics; Lepidoptera; Lysine; Models, Molecular; Molecular Sequence Data; Oocytes; Phenanthrolines; Potassium; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium; Tryptophan; Xenopus laevis

2007
Effect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant.
    Journal of molecular biology, 2008, Jan-25, Volume: 375, Issue:4

    Topics: alpha-Crystallin B Chain; alpha-Synuclein; Amino Acid Substitution; Amyloid; Aspartic Acid; Citrate (si)-Synthase; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Heat-Shock Proteins, Small; Hot Temperature; Humans; Insulin; Molecular Chaperones; Phosphorylation; Protein Denaturation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Sodium Dodecyl Sulfate; Surface-Active Agents; Urea

2008
A potent, versatile disulfide-reducing agent from aspartic acid.
    Journal of the American Chemical Society, 2012, Mar-07, Volume: 134, Issue:9

    Topics: Aspartic Acid; Creatine Kinase; Disulfides; Dithiothreitol; Molecular Structure; Oxidation-Reduction; Papain; Stereoisomerism

2012
The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds.
    Molecular biology of the cell, 2012, Volume: 23, Issue:17

    Topics: Adenosine Triphosphatases; Aspartic Acid; Binding Sites; Diamide; Dithiothreitol; DNA-Binding Proteins; Heat-Shock Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Maleates; Oxidative Stress; Pentacyclic Triterpenes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfhydryl Compounds; Transcription Factors; Triterpenes; Unfolded Protein Response

2012
Cysteine mutagenesis reveals alternate proximity between transmembrane domain 2 and hairpin loop 1 of the glutamate transporter EAAT1.
    Amino acids, 2014, Volume: 46, Issue:7

    Topics: Amino Acid Sequence; Aspartic Acid; Cadmium Chloride; Cross-Linking Reagents; Cysteine; Dithiothreitol; Excitatory Amino Acid Transporter 1; Glutamic Acid; HeLa Cells; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenanthrolines; Protein Structure, Tertiary; Structure-Activity Relationship

2014
A complex relative motion between hairpin loop 2 and transmembrane domain 5 in the glutamate transporter GLT-1.
    The international journal of biochemistry & cell biology, 2015, Volume: 60

    Topics: Aspartic Acid; Dithiothreitol; Excitatory Amino Acid Transporter 2; Glutamic Acid; HeLa Cells; Humans; Kinetics; Mesylates; Protein Structure, Secondary; Protein Structure, Tertiary; Sodium Chloride; Sulfhydryl Compounds

2015