aspartic acid has been researched along with cyclic gmp in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 34 (56.67) | 18.7374 |
1990's | 10 (16.67) | 18.2507 |
2000's | 11 (18.33) | 29.6817 |
2010's | 5 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Goridis, C | 1 |
Aronica, E; Bruno, V; Canonico, PL; Catania, MV; Copani, A; Gaviraghi, G; Nicoletti, F; Ratti, E; van Amsterdam, FT | 1 |
Marini, A; Novelli, A | 1 |
Bazarnyĭ, VV; Iastrebov, AP | 1 |
Gallo, V; Giovannini, C; Levi, G | 2 |
Cler, J; Emmett, MR; Iyengar, S; Mick, S; Oei, E; Rao, TS; Wood, PL | 1 |
Brooker, G; Costa, E; Danysz, W; Wroblewski, JT | 1 |
Hoffman, PL; Moses, F; Rabe, CS; Tabakoff, B | 1 |
Baron, BM; Dudley, MW; McCarty, DR; Miller, FP; Reynolds, IJ; Schmidt, CJ | 1 |
Rao, TS; Wood, PL | 1 |
Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
McCaslin, PP; Morgan, WW | 5 |
Bredt, DS; Snyder, SH | 1 |
Cheney, DL; Lehmann, J; McPherson, SE; Steel, D; Wood, PL | 1 |
Carter, CJ; Noel, F; Scatton, B | 2 |
Chapman, AG; Hutchison, A; Lehmann, J; Meldrum, BS; Tsai, C; Wood, PL | 1 |
Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B | 1 |
Carter, C; Noel, F; Scatton, B | 1 |
Garthwaite, J | 2 |
Canning, HM; Leach, MJ; Marden, CM | 1 |
Garthwaite, G; Garthwaite, J | 1 |
Bennett, DA; Bernard, P; Boehm, C; Lehmann, J; McPherson, S; Murphy, DE; Pastor, G; Schneider, J; Steel, DJ; Tsai, C | 1 |
Anand, H; Badman, G; Collins, JF; Dixon, AJ; Roberts, PJ | 1 |
Gallo, V; Levi, G | 1 |
Foster, GA; Roberts, PJ | 2 |
Burgal, M; Grisolía, S; Jordá, A | 1 |
Roberts, PJ | 1 |
Bruni, J; Hammond, EJ; Wilder, BJ | 1 |
Coyle, JT; Ferkany, JW; Zaczek, R | 1 |
Burgal, M; Grisolía, S; Jordá, A; Lizondo, J | 1 |
Itoh, T; Kamisaki, Y; Nakamoto, K; Wada, K | 1 |
Janáky, R; Marnela, KM; Oja, SS; Saransaari, P; Varga, V | 1 |
Beavo, JA; Colbran, JL; Corbin, JD; Francis, SH; Haik, TL; McAllister-Lucas, LM; Seger, D; Sonnenburg, WK; Turko, IV | 1 |
Scott, SP; Tanaka, JC | 1 |
Lee, YJ; Tsai, LH; Wu, J | 1 |
He, Y; Karpen, JW | 1 |
Dettmer, D; Hermsdorf, T; Kronbach, T; Richter, W; Unciuleac, L | 1 |
Haystead, TA; Liu, X; MacDonald, JA; Nakamoto, RK; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
Arendt, A; Brannock, MT; Hargrave, PA; McDowell, JH; Miller, RL; Robinson, PR; Smith, WC | 1 |
Kraus, MM; Prast, H | 1 |
Dolkart, PH; Ferrendelli, JA; Gorell, JM | 1 |
Lee, JC; Lin, SH | 1 |
Arrowsmith, CH; Brown, G; Edwards, AM; Kuznetsova, E; Proudfoot, M; Savchenko, A; Yakunin, AF | 1 |
Akiyama, M; Katusic, ZS; Santhanam, AV; Sessa, WC; Smith, LA; Sorenson, J | 1 |
Barrett, R; Bush, RA; Dizhoor, AM; Fain, GL; Olshevskaya, EV; Peshenko, IV; Savchenko, AB; Sieving, PA; Woodruff, ML | 1 |
Chieffi Baccari, G; D'Aniello, A; Di Giovanni, M; Di Maro, A; Monteforte, R; Santillo, A | 1 |
Kato, T; Kurahashi, H; Nishizawa, H; Pryor-Koishi, K; Sekiya, T; Suzuki, M; Tada, S; Udagawa, Y | 1 |
Cervetto, C; Marcoli, M; Maura, G | 1 |
Agasing, A; Green, J; Lacey, M; Lowry, R | 1 |
Aguilera, J; Balderas, A; Guillem, AM; Hernández-Kelly, LC; Martínez-Lozada, Z; Ortega, A | 1 |
Grigorenko, BL; Knyazeva, MA; Nemukhin, AV | 1 |
Aliverti, A; Cossu, F; Gourlay, L; Landini, P; Mauri, P; Motta, S; Rossi, E | 1 |
1 review(s) available for aspartic acid and cyclic gmp
Article | Year |
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Central actions of valproic acid in man and in experimental models of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Action Potentials; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Aspartic Acid; Brain; Cyclic GMP; Dyskinesia, Drug-Induced; Electric Stimulation; Electrophysiology; Epilepsies, Partial; gamma-Aminobutyric Acid; Glycine; Humans; Nervous System Diseases; Neurons; Seizures; Serotonin; Succinate-Semialdehyde Dehydrogenase; Succinates; Valproic Acid | 1981 |
59 other study(ies) available for aspartic acid and cyclic gmp
Article | Year |
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The effect of flash illumination on the endogenous cyclic GMP content of isolated frog retinae.
Topics: Animals; Anura; Aspartic Acid; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Photic Stimulation; Photoreceptor Cells; Rana esculenta; Retina; Rhodopsin | 1977 |
Interaction between beta-N-methylamino-L-alanine and excitatory amino acid receptors in brain slices and neuronal cultures.
Topics: Amino Acids, Diamino; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cyanobacteria Toxins; Cyclic GMP; Hippocampus; Hydrolysis; In Vitro Techniques; Neurons; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
DL-threo-3-hydroxyaspartate reduces NMDA receptor activation by glutamate in cultured neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; Kainic Acid; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
[The mechanism of the immunotropic effect of aspartic acid].
Topics: Adjuvants, Immunologic; Anemia, Hypochromic; Animals; Aspartic Acid; Cyclic AMP; Cyclic GMP; DNA; Drug Evaluation, Preclinical; Drug Therapy, Combination; Male; Organometallic Compounds; Polysaccharides; Rats; Rats, Inbred Strains; T-Lymphocytes | 1990 |
Modulation of non-N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Granulocytes; Ibotenic Acid; Kainic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
In vivo antagonism of agonist actions at N-methyl-D-aspartate and N-methyl-D-aspartate-associated glycine receptors in mouse cerebellum: studies of 1-hydroxy-3-aminopyrrolidone-2.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Male; Mice; N-Methylaspartate; Pyrrolidinones; Receptors, Glycine; Receptors, Neurotransmitter | 1990 |
Quisqualic acid modulates kainate responses in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Interactions; Kainic Acid; Nitroprusside; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Brain; Cerebellum; Cyclic GMP; Glycine; Injections, Intraventricular; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
N-methyl-D-aspartate receptors and ethanol: inhibition of calcium flux and cyclic GMP production.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Ethanol; Glycine; Granulocytes; N-Methylaspartate; Osmolar Concentration; Phencyclidine; Picrotoxin | 1989 |
Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Calcium; Cerebellum; Cerebral Cortex; Cyclic GMP; Cytosol; Guanine Nucleotides; Hippocampus; Intracellular Membranes; Kinetics; Male; N-Methylaspartate; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1989 |
NMDA-coupled and uncoupled forms of the PCP receptor: preliminary in vivo evidence for PCP receptor subtypes.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Harmaline; Ketamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Reference Values | 1989 |
In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Cycloserine; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1989 |
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Cultured cerebellar cells as an in vitro model of excitatory amino acid receptor function.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Models, Neurological; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Antagonism of N-methyl-D-aspartate (NMDA) evoked increases in cerebellar cGMP and striatal ACh release by phencyclidine (PCP) receptor agonists: evidence for possible allosteric coupling of NMDA and PCP receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Brain Chemistry; Cerebellum; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; N-Methylaspartate; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1987 |
Raised extracellular potassium relieves the blockade by magnesium of NMDA-induced cerebellar cyclic GMP production.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Extracellular Space; Magnesium; Magnesium Sulfate; N-Methylaspartate; Osmolar Concentration; Potassium; Potassium Chloride; Rats | 1987 |
CGS 19755 is a potent and competitive antagonist at NMDA-type receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Binding, Competitive; Blood-Brain Barrier; Cerebellum; Cyclic GMP; Harmaline; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Sodium dependence of NMDA's effects on cyclic GMP production in immature rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium Channels; Cerebellum; Cyclic GMP; N-Methylaspartate; Rats; Sodium | 1988 |
Cellular uptake disguises action of L-glutamate on N-methyl-D-aspartate receptors. With an appendix: diffusion of transported amino acids into brain slices.
Topics: Aging; Animals; Aspartic Acid; Biological Transport; Brain; Cyclic GMP; Diffusion; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1985 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
Cellular origins of cyclic GMP responses to excitatory amino acid receptor agonists in rat cerebellum in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Nitroprusside; Purkinje Cells; Rats; Tetrodotoxin | 1987 |
CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Novel kainic acid analogues. Effects on cyclic GMP content of adult rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship | 1986 |
2-Amino-7-phosphonoheptanoic acid, a selective N-methyl-D-aspartate antagonist, blocks swim-induced elevation of cerebellar cyclic guanosine monophosphate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Female; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Swimming | 1986 |
Ionic mechanisms implicated in the stimulation of cerebellar cyclic GMP levels by N-methyl-D-aspartate.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Male; N-Methylaspartate; Nifedipine; Rats; Zinc | 1987 |
Glutamate as a putative transmitter in the cerebellum: stimulation by GABA of glutamic acid release from specific pools.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Male; Neurotransmitter Agents; Rats; Synaptosomes; Veratridine | 1981 |
Stimulation of rat cerebellar guanosine 3',5'-cyclic monophosphate (cyclic GMP) levels: effects of amino acid antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Protoveratrines; Rats; Rats, Inbred Strains | 1981 |
Effects of N-acetyl aspartate, aspartate, and glutamate on cAMP and cGMP levels in developing rat cerebral cortex.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Glutamates; Glutamic Acid; Guanylate Cyclase; Male; Rats; Rats, Inbred Strains | 1982 |
Excitatory amino acid receptors and guanosine 3',5'-cyclic monophosphate in incubated slices of immature and adult rat cerebellum.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1982 |
Neurochemical and pharmacological correlates of inferior olive destruction in the rat: attenuation of the events mediated by an endogenous glutamate-like substance.
Topics: Afferent Pathways; Animals; Aspartic Acid; Brain Mapping; Cyclic GMP; Female; Glutamates; Glutamic Acid; Nerve Fibers; Olivary Nucleus; Purkinje Cells; Pyridines; Rats; Rats, Inbred Strains; Synaptic Transmission; Synaptosomes | 1983 |
Receptors for excitatory amino acids: binding studies and stimulation of cyclic GMP levels.
Topics: Animals; Aspartic Acid; Cyclic GMP; Glutamates; Humans; Neurons; Receptors, Amino Acid; Receptors, Cell Surface | 1981 |
Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Pyrrolidines; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1982 |
Inhibition by N-acetyl-aspartate of aspartate binding to a proteolipid fraction from rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Male; N-Methylaspartate; Protein Binding; Proteolipids; Rats; Rats, Inbred Strains | 1984 |
Nitric oxide inhibition of the depolarization-evoked glutamate release from synaptosomes of rat cerebellum.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nitric Oxide; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Synaptosomes | 1995 |
Interactions of gamma-L-glutamyltaurine with excitatory aminoacidergic neurotransmission.
Topics: Aging; Animals; Aspartic Acid; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclic GMP; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Mice; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synaptic Transmission; Synaptosomes; Taurine | 1994 |
An essential aspartic acid at each of two allosteric cGMP-binding sites of a cGMP-specific phosphodiesterase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Allosteric Site; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Blotting, Western; Cattle; Cyclic GMP; Kinetics; Lung; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Recombinant Proteins | 1995 |
Three residues predicted by molecular modeling to interact with the purine moiety alter ligand binding and channel gating in cyclic nucleotide-gated channels.
Topics: Amino Acid Substitution; Amino Acids; Animals; Aspartic Acid; Cattle; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Evoked Potentials; Ion Channels; Ligands; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Nickel; Patch-Clamp Techniques; Phenylalanine; Protein Binding; Protons; Purine Nucleotides; Rod Cell Outer Segment | 1998 |
Effect of excitatory amino acid neurotransmitters on acid secretion in the rat stomach.
Topics: 1-Methyl-3-isobutylxanthine; 2-Amino-5-phosphonovalerate; Animals; Aspartate Aminotransferases; Aspartic Acid; Cyclic AMP; Cyclic GMP; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Histamine; Histamine Release; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Agonists; Neurons; Oxotremorine; Pentagastrin; Piperazines; Rats; Rats, Sprague-Dawley; Stomach | 1999 |
Probing the interactions between cAMP and cGMP in cyclic nucleotide-gated channels using covalently tethered ligands.
Topics: Allosteric Regulation; Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Eye Proteins; Ion Channels; Ligands; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Rod Cell Outer Segment; Xenopus laevis | 2001 |
Identification of substrate specificity determinants in human cAMP-specific phosphodiesterase 4A by single-point mutagenesis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Binding, Competitive; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphodiesterase Inhibitors; Polymerase Chain Reaction; RNA, Messenger; Rolipram; Sequence Alignment; Substrate Specificity | 2001 |
Site-specific phosphorylation and point mutations of telokin modulate its Ca2+-desensitizing effect in smooth muscle.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Calcium; Colforsin; Culture Techniques; Cyclic GMP; Ileum; Microcystins; Microscopy, Electron; Muscle Proteins; Muscle Relaxation; Muscle, Smooth; Myosin-Light-Chain Kinase; Peptide Fragments; Peptides; Peptides, Cyclic; Phosphorylation; Point Mutation; Rabbits; Serine | 2001 |
Activation of arrestin: requirement of phosphorylation as the negative charge on residues in synthetic peptides from the carboxyl-terminal region of rhodopsin.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arrestin; Aspartic Acid; Cattle; Cyclic GMP; Cysteic Acid; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Peptide Fragments; Phosphorylation; Rhodopsin; Rod Cell Outer Segment; Sulfhydryl Compounds; Vision, Ocular | 2001 |
Involvement of nitric oxide, cyclic GMP and phosphodiesterase 5 in excitatory amino acid and GABA release in the nucleus accumbens evoked by activation of the hippocampal fimbria.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aspartic Acid; Catheterization; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; Electrodes, Implanted; Enzyme Inhibitors; Excitatory Amino Acids; Fornix, Brain; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nucleus Accumbens; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley | 2002 |
Regional levels of glucose, amino acids, high energy phosphates, and cyclic nucleotides in the central nervous system during hypoglycemic stupor and behavioral recovery.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Central Nervous System; Coma; Cyclic AMP; Cyclic GMP; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glycogen; Hypoglycemia; Insulin; Male; Mice; Phosphocreatine; Recovery of Function | 1976 |
Linkage of multiequilibria in DNA recognition by the D53H Escherichia coli cAMP receptor protein.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli Proteins; Galactose; Histidine; Kinetics; Lactose; Point Mutation; Protein Binding; Protein Conformation; Thermodynamics | 2002 |
The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Aspartic Acid; Calcium; Chromatography, Thin Layer; Cloning, Molecular; Conserved Sequence; Cyclic AMP; Cyclic CMP; Cyclic GMP; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Hydrolysis; Ions; Kinetics; Magnesium; Manganese; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nickel; Nucleotidases; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; RNA Nucleotidyltransferases; Substrate Specificity | 2004 |
Expression and function of recombinant S1179D endothelial NO synthase in human pial arteries.
Topics: Adult; Aspartic Acid; Cerebral Arteries; Cyclic GMP; Endothelium, Vascular; Epilepsy; Female; Gene Expression; Humans; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Point Mutation; Recombinant Proteins; Serine; Vasodilation | 2005 |
Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark.
Topics: Adaptation, Ocular; Animals; Aspartic Acid; Calcium; Cyclic GMP; Cysteine; Dark Adaptation; Disease Models, Animal; Electroretinography; Gene Expression Regulation; Glycine; Guanylate Cyclase-Activating Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Physical Stimulation; Retina; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Rhodopsin; Tyrosine | 2007 |
D-Aspartate affects secretory activity in rat Harderian gland: molecular mechanism and functional significance.
Topics: Amino Acid Isomerases; Animals; Aspartic Acid; Cyclic AMP; Cyclic GMP; D-Aspartic Acid; Extracellular Signal-Regulated MAP Kinases; Harderian Gland; Liver; Male; MAP Kinase Kinase 4; Microscopy, Electron, Transmission; Nitric Oxide Synthase; Porphyrins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2009 |
Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia.
Topics: Adult; Aspartic Acid; Case-Control Studies; Cyclic GMP; Female; Gestational Age; Glutamic Acid; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Inhibition of presynaptic release-facilitatory kainate autoreceptors by extracellular cyclic GMP.
Topics: Animals; Aspartic Acid; Autoreceptors; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synaptosomes | 2010 |
Identification of the YfgF MASE1 domain as a modulator of bacterial responses to aspartate.
Topics: Amino Acid Motifs; Aspartic Acid; Bacterial Proteins; Benzoquinones; Chemotaxis; Cyclic GMP; Mutagenesis, Site-Directed; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Salmonella enterica | 2013 |
GLAST/EAAT1 regulation in cultured Bergmann glia cells: role of the NO/cGMP signaling pathway.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium Signaling; Cells, Cultured; Chick Embryo; Cyclic GMP; Neuroglia; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Primary Cell Culture; Signal Transduction | 2014 |
Analysis of proton wires in the enzyme active site suggests a mechanism of c-di-GMP hydrolysis by the EAL domain phosphodiesterases.
Topics: Amino Acid Substitution; Aspartic Acid; Catalytic Domain; Cyclic GMP; Escherichia coli; Escherichia coli Proteins; Gene Expression; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Kinetics; Molecular Dynamics Simulation; Phosphoric Diester Hydrolases; Phosphorus; Protein Structure, Secondary; Protons; Quantum Theory; Structure-Activity Relationship; Thermodynamics; Water | 2016 |
Cellulose production is coupled to sensing of the pyrimidine biosynthetic pathway via c-di-GMP production by the DgcQ protein of Escherichia coli.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Biosynthetic Pathways; Cellulose; Cyclic GMP; DNA; Escherichia coli; Escherichia coli Proteins; Phosphorus-Oxygen Lyases; RNA; Uridine Triphosphate | 2017 |