aspartic acid has been researched along with carbamates in 159 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 144 (90.57) | 18.7374 |
| 1990's | 2 (1.26) | 18.2507 |
| 2000's | 11 (6.92) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (1.26) | 2.80 |
| Authors | Studies |
|---|---|
| Opella, SJ; Phillips, HM; Roberts, MF; Schaffer, MH; Stark, GR | 1 |
| Crandall, DE; Tremblay, GC | 1 |
| Chevallier, MR; Greth, ML; Lacroute, F | 1 |
| Christopherson, RI; Jones, ME; Matsuura, T | 1 |
| Christopherson, RI; Jones, ME | 1 |
| Golovinski, E; Kharbov, D; Raducheva, T; Rutkov, A; Velianov, D | 1 |
| Grisolía, S; Martínez-Ramón, A; Rubio, V | 1 |
| Prescott, LM; Shindler, DB | 1 |
| Butterworth, PJ; Grayson, JE; Yon, RJ | 1 |
| Crabeel, M; Gigot, D; Glansdorff, N; Legrain, C; Piéard, A; Stalon, V | 1 |
| Johnson, RK | 1 |
| Kidder, GW; Nolan, LL | 1 |
| Chance, B; Erecińska, M; Rafalowska, U | 1 |
| Oberholzer, VG; Palmer, T | 1 |
| Inoue, Y; Matsumoto, I; Ohkura, T; Rudewicz, PJ | 1 |
| Gelbard, AS; Kaseman, DS; Meister, A; Rosenspire, KC | 1 |
| Kameyama, A; Miura, K | 1 |
| Platt, T; Weber, K; Weiner, AM | 1 |
| Bernhardt, SA; Davis, RH | 1 |
| Longton, RW | 1 |
| Chang, TY; Jones, ME | 2 |
| Karasek, MA; Pillarisetty, RJ | 1 |
| Campbell, JW; Tramell, PR | 1 |
| Buckman, T | 1 |
| Benisek, WF | 1 |
| Bhide, SV | 2 |
| Coleman, MS; Jones, ME | 1 |
| Olszowy, J; Switzer, RL | 1 |
| Adair, LB; Jones, ME | 1 |
| Shigesada, K; Tatibana, M | 1 |
| Buchanan, JM | 1 |
| Kurelec, B | 1 |
| Gülen, S; Smith, PC; Tremblay, GC | 1 |
| Seaver, SS; Stark, GR; Swyryd, EA | 1 |
| Kretchmer, N | 1 |
| Renfree, MB | 1 |
| Martin, DW; Murphy, B | 1 |
| Jund, R; Lacroute, F | 1 |
| Drillien, R; Lacroute, F | 1 |
| Gerhart, JC; Nelbach, ME; Pigiet, VP; Schachman, HK | 1 |
| Schaffer, MH; Stark, GR | 1 |
| Radford, A | 3 |
| Colman, PD; Markus, G | 1 |
| London, RE; Schmidt, PG | 1 |
| Evans, DR; McMurray, CH; Sykes, BD | 1 |
| Glansdorff, N; Halleux, P; Legrain, C; Stalon, V | 1 |
| Richards, KE; Williams, RC | 1 |
| Cohlberg, JA; Pigiet, VP; Schachman, HK | 1 |
| Cybis, J; Piotrowska, M; Weglenski, P | 1 |
| Griffin, JH; Rosenbusch, JP | 1 |
| Jacobson, GR; Stark, GR | 1 |
| Heyde, E; Morrison, JF; Nagabhushanam, A | 1 |
| Heyde, E; Morrison, JF | 1 |
| Gasser, FJ; Wedler, FC | 1 |
| Exinger, F; Korch, CT; Lacroute, F | 1 |
| Brouwer, A; Hoek, JB; Meijer, AJ; Reijngoud, DJ; Tager, JM | 1 |
| Bibbs, BS; Flora, JB; Schmidt, RR; Vassef, AA; Weeks, JG | 1 |
| Yashphe, J | 1 |
| Dunn, JH; Herrmann, EC; Schmidt, RR | 1 |
| Ito, K; Uchino, H | 1 |
| Yon, RJ | 1 |
| Knott, CE; Smith, PC; Tremblay, GC | 1 |
| Kennedy, J | 1 |
| Weber, K | 1 |
| Blakley, RL; Vitols, E | 1 |
| Bethell, MR; Jones, ME; Smith, KE; White, JS | 1 |
| Stadtman, ER | 1 |
| Modebe, MO; Porter, RW; Stark, GR | 1 |
| Collins, KD; Stark, GR | 2 |
| Atkinson, DE; Bigler, WN | 1 |
| Natale, PJ; Tremblay, GC | 1 |
| Davies, GE; Stark, GR; Vanaman, TC | 1 |
| Schmidt, PG; Stark, GR; Sykes, BD | 1 |
| Stark, GR; Vanaman, TC | 1 |
| Tokushige, M | 1 |
| Gregory, DS; Wilson, IB | 1 |
| Rosenbusch, JP; Weber, K | 1 |
| Hammes, GG; Porter, RW; Stark, GR | 1 |
| Stark, GR | 1 |
| Hammes, GG; Wu, CW | 1 |
| Eckfeldt, J; Hammes, GG; Mohr, SC; Wu, CW | 1 |
| Jones, ME | 1 |
| Camakaris, J; Cotton, RG; Danks, DM | 1 |
| Levin, B | 1 |
| Kornberg, A; Setlow, P | 1 |
| Jones, ME; Prescott, LM | 2 |
| Colley, L; Dicker, SE; Elliott, AB; Huggins, AK; Rowe, WC | 1 |
| Little, RC; Nishikawara, MT; Waymire, JC | 1 |
| Flink, EB; Lizarralde, G; Looney, T; Shane, SR | 1 |
| Bourget, PA; Tremblay, GC | 2 |
| Davis, RH | 1 |
| Hoogenraad, NJ; Kretchmer, N; Levine, RL | 1 |
| Jones, ME; Shoaf, WT | 1 |
| Chu, P; Miller, AL | 1 |
| Herries, DG | 1 |
| Merker, HJ; Spors, S | 1 |
| Crokaert, R; Wisenfeld, M | 1 |
| Davis, RH; Grindle, M | 1 |
| Kaplan, JG; Lue, PF | 4 |
| Karasawa, T; Minaki, Y; Miyazaki, H; Yoshimura, Y | 1 |
| Chibata, I; Kakimoto, T; Kato, J; Nishimura, N; Shibatani, T | 1 |
| Bernhardt, S; Davis, RH; Williams, LG | 1 |
| Hammes, GG; Porter, RW; Wu, CW | 1 |
| Toninello, A; Zoccarato, F | 1 |
| Inagaki, A; Tatibana, M | 1 |
| Bussel, JB; Markus, G; McClintock, DK | 1 |
| Bernhardt, SA; Davis, RH; Williams, LG | 1 |
| Jackson, JF; Ong, BL | 1 |
| Kirschner, MW; Schachman, HK | 2 |
| Chan, MS; Endrenyi, L; Wong, JT | 1 |
| Chamberlin, MJ; Gray, CW | 1 |
| Minaki, Y; Miyazaki, H; Yoshimura, Y | 1 |
| Hill, JM; Woodward, VW | 1 |
| Bayer, SM; McMurray, WC | 1 |
| Baldeschwieler, JD; Schmidt, PG; Stark, GR | 1 |
| Cohen, PP; Lan, SJ; Sallach, HJ | 1 |
| Bonciocat, C; Chiosa, L; Niculescu, V; Stancu, C | 1 |
| Buchowicz, J; Mazuś, B | 1 |
| Sprecher, M; Sprinson, DB | 1 |
| Grisolia, S; Hunninghake, D | 1 |
| Balestrieri, C; Cimino, F; Cittadini, D; De Cristofaro, D | 1 |
| Senior, JR; Shafritz, DA | 1 |
| Hubbard, JS; Stadtman, ER | 1 |
| Hisata, T; Tatibana, M | 1 |
| DeBons, FE; Loudon, GM | 1 |
| DeGrado, WF; Jackson, S; Mousa, S; Olson, RE; Rafalski, M; Rockwell, A; Roderick, J; Xue, CB | 1 |
| Cagiano, R; Cassano, T; Cuomo, V; Kendrick, KM; Pietra, C; Steardo, L; Tattoli, M; Trabace, L | 1 |
| Ihara, Y; Mitsumori, R; Morishima-Kawashima, M; Qi, Y; Sato, T | 1 |
| DONACHIE, WD | 1 |
| AMSTEY, M; BROWN, O; MCCARTY, KS; WOODSON, B | 1 |
| COHEN, PP; LINDSAY, RH; NAKAGAWA, H | 1 |
| BERLINGUET, L; CHARBONNEAU, R | 2 |
| HAGER, SE; HERZFELD, A; JONES, ME | 1 |
| BRESNICK, E | 1 |
| BAROEN, JP; CROKAERT, R | 1 |
| KLEPPE, K | 1 |
| Annunziato, L; Castaldo, P; D'Amico, M; Martire, M; Preziosi, P; Taglialatela, M | 1 |
| Brennan, DL; Cottrell, KM; Fulghum, JR; Gates, CA; Hsiao, HM; Kwong, AD; Lin, C; Lin, K; Luong, YP; Ma, S; Maxwell, JP; Perni, RB; Rao, BG; Wei, YY | 1 |
| Nakajima, T; Shimamoto, K; Takaoka, K; Tatsu, Y; Yumoto, N | 1 |
| Komano, H; Kurono, Y; Maeda, Y; Nishimura, M; Sai, X; Shiraishi, H; Wang, HQ; Yanagisawa, K | 1 |
| Brennan, DL; Frantz, JD; Fulghum, JR; Gates, CA; Kwong, AD; Lin, C; Lin, K; Luong, YP; Ma, S; Perni, RB; Rao, BG; Wei, YY | 1 |
| Clemente-Jiménez, JM; Las Heras-Vázquez, FJ; Martínez-Rodríguez, S; Rodríguez-Vico, F | 1 |
| Harrer, T; Horn, AH; Meiselbach, H; Sticht, H | 1 |
| Bethel, CR; Bonomo, RA; Hujer, AM; Hujer, KM; Leonard, DA; Schneider, KD; Smith, BA | 1 |
| Bihani, SC; Das, A; Ferrer, JL; Hosur, MV; Prashar, V | 1 |
| Adenusi, H; Bodo, E; Le Donne, A; Onofri, S | 1 |
| Liu, WT; Sun, HB; Wang, W; Wu, SL; Yu, YX; Zhang, LL | 1 |
7 review(s) available for aspartic acid and carbamates
| Article | Year |
|---|---|
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Carcinoma, Hepatocellular; Dietary Proteins; Glutamates; Humans; Liver; Liver Neoplasms; Magnesium; Mice; Models, Chemical; Neurospora; Phosphotransferases; Pyrimidines; Rats; Spleen; Transferases; Uracil Nucleotides; Urea | 1972 |
The amidotransferases.
Topics: Anthranilate Synthase; Asparagine; Aspartic Acid; Binding Sites; Carbamates; Cytosine Nucleotides; Fructosephosphates; Glutamine; Ligases; Liver; Macromolecular Substances; NAD; Organophosphorus Compounds; Protein Conformation; Pyrimidine Nucleotides; Ribose; RNA, Transfer; Transaminases; Xanthines | 1973 |
Developmental biochemistry--a relevant endeavor. Borden Award address.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carbamates; Carbohydrate Metabolism, Inborn Errors; Cetacea; Chick Embryo; Galactosidases; Glucose; Glycoside Hydrolases; Growth; Intestinal Mucosa; Intestine, Small; Ligases; Pyrimidines; Rats; Transferases; Tyrosine Transaminase | 1970 |
The control of nucleotide biosynthesis.
Topics: Aspartic Acid; Carbamates; Enzymes; Escherichia coli; Lactobacillus; Ligases; Nucleotides; Oxidoreductases; Phosphates; Phosphotransferases; Purines; Thymidine Kinase; Transferases | 1968 |
[Allosteric effects and metabolic regulation].
Topics: Aspartic Acid; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Enzymes; Metabolism; Muramidase; Sulfides; Transferases | 1970 |
Regulation of pyrimidine and arginine biosynthesis in mammals.
Topics: Amidohydrolases; Animals; Arginine; Aspartic Acid; Bacillus; Basidiomycota; Carbamates; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Enzyme Induction; Enzyme Repression; Escherichia coli; Feedback; Humans; Ligases; Lyases; Mice; Neurospora; Nucleotides; Ornithine Carbamoyltransferase; Orotic Acid; Oxidoreductases; Pentosyltransferases; Phosphotransferases; Pseudomonas; Pyrimidines; Saccharomyces; Transferases; Uracil; Urea | 1970 |
Hereditary metabolic disorders of the urea cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; Humans; Ligases; Liver; Lyases; Models, Chemical; Ornithine Carbamoyltransferase; Phosphotransferases; Succinates; Urea | 1971 |
152 other study(ies) available for aspartic acid and carbamates
| Article | Year |
|---|---|
Evidence from 13C NMR for protonation of carbamyl-P and N-(phosphonacetyl)-L-aspartate in the active site of aspartate transcarbamylase.
Topics: Aspartic Acid; Binding Sites; Carbamates; Carbamyl Phosphate; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Organophosphonates; Protein Binding; Structure-Activity Relationship | 1976 |
Pyrimidine biosynthesis and its regulation in embryos of the sea urchin, Arbacia punctulata.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Azauridine; Bicarbonates; Carbamates; Carbamoyl-Phosphate Synthase (Ammonia); Dihydroorotase; Dihydroorotate Oxidase; Embryo, Nonmammalian; Female; Kinetics; Male; Orotate Phosphoribosyltransferase; Orotic Acid; Pyrimidines; Sea Urchins; Species Specificity; Uracil | 1976 |
Ureidosuccinic acid permeation in Saccharomyces cerevisiae.
Topics: Amino Acids; Aspartic Acid; Azides; Binding, Competitive; Biological Transport; Carbamates; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlorhexidine; Dinitrophenols; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship | 1977 |
Radioassay of dihydroorotase utilizing ion-exchange chromatography.
Topics: Amidohydrolases; Animals; Aspartic Acid; Carbamates; Carcinoma, Ehrlich Tumor; Chromatography, Ion Exchange; Dihydroorotase; Mice; Orotic Acid | 1978 |
Interconversion of carbamayl-L-aspartate and L-dihydroorotate by dihydroorotase from mouse Ehrlich ascites carcinoma.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Carcinoma, Ehrlich Tumor; Diethyl Pyrocarbonate; Dihydroorotase; Hydrogen-Ion Concentration; Kinetics; Mathematics; Mice; Orotic Acid | 1979 |
[Effect of D,L-ureidosuccinic dihydrazide on the biological properties of Pseudomonas pseudomallei and Salmonella typhimurium].
Topics: Animals; Antimetabolites; Aspartic Acid; Carbamates; Cell Division; Kinetics; Mice; Oxygen Consumption; Phagocytosis; Pseudomonas; Rabbits; Salmonella typhimurium; Virulence | 1979 |
Autoradiographic evidence of increased incorporation of aspartate and of carbamoyl aspartate in fibroblasts from a Lesch-Nyhan patient.
Topics: Aspartic Acid; Autoradiography; Carbamates; Cell Nucleus; Cells, Cultured; Child, Preschool; Cycloheximide; Fibroblasts; Humans; Lesch-Nyhan Syndrome; Skin | 1979 |
Improvements on the Prescott-Jones method for the colorimetric analysis of ureido compounds.
Topics: Aspartic Acid; Carbamates; Citrulline; Colorimetry; Urea | 1979 |
Wheat-germ aspartate transcarbamoylase. Steady-state kinetics and stereochemistry of the binding site for L-aspartate.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamates; Carbamyl Phosphate; Kinetics; Molecular Conformation; Seeds; Triticum | 1979 |
Structural and regulatory mutations allowing utilization of citrulline or carbamoylaspartate as a source of carbamoylphosphate in Escherichia coli K-12.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Citrulline; Cytosine Nucleotides; Escherichia coli; Genes; Genes, Regulator; Mutation; Ornithine Carbamoyltransferase; Recombination, Genetic | 1976 |
Reversal of toxicity and antitumor activity of N-(phosphonacetyl)-L-aspartate by uridine or carbamyl-DL-asparate in vivo.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Body Weight; Carbamates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1977 |
Enzymatic synthesis of labeled carbamyl- aspartic acid.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Carbamyl Phosphate; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Eukaryota; Evaluation Studies as Topic; Methods | 1975 |
The effect of aspartate on citrate metabolism in the cytosolic fraction of brain under conditions of normoxia, hypoxia and anaesthesia.
Topics: Anesthesia, General; Animals; Aspartic Acid; Brain; Carbamates; Citrates; Cytosol; Hypoxia, Brain; Ketoglutaric Acids; Microsomes; Mitochondria; Rats; Urea | 1975 |
Increased excretion of N-carbamoyl compounds in patients with urea cycle defects.
Topics: Alanine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Aspartic Acid; Carbamates; Child; Child, Preschool; Chromatography, Paper; Chromatography, Thin Layer; Humans; Infant, Newborn; Ligases; Lyases; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 1976 |
Fast atom bombardment tandem mass spectrometric analysis of N-carbamoylamino acids.
Topics: Amino Acids; Aspartic Acid; beta-Alanine; Carbamates; Humans; Ornithine Carbamoyltransferase Deficiency Disease; Spectrometry, Mass, Fast Atom Bombardment | 1991 |
Enzymatic syntheses of carbamyl phosphate, L-citrulline, and N-carbamyl L-aspartate labeled with either 13N or 11C.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Carbon Isotopes; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Female; Isotope Labeling; Mice; Mice, Inbred Strains; Nitrogen Radioisotopes; Ornithine Carbamoyltransferase; Radioisotope Dilution Technique; Tissue Distribution | 1985 |
Changes in activities of carbamoylphosphate synthase and aspartate carbamoyltransferase in the life cycle of the blowfly "Aldrichina grahami".
Topics: Animals; Aspartic Acid; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Citrulline; Diptera; DNA; Larva; Metamorphosis, Biological; Microsomes; Mitochondria; Phosphotransferases; Pupa; RNA; Transferases | 1970 |
Amino-terminal sequence analysis of proteins purified on a nanomole scale by gel electrophoresis.
Topics: Acrylamides; Amino Acid Sequence; Amino Acids; Aspartic Acid; Bacterial Proteins; Carbamates; Chromatography, Thin Layer; Coliphages; Dansyl Compounds; DNA, Viral; Electrophoresis; Galactosidases; Methods; Microchemistry; Muramidase; Proteins; RNA, Viral; Sodium Dodecyl Sulfate; Staining and Labeling; Thiocyanates; Transferases; Tryptophan Synthase; Viral Proteins | 1972 |
Carbamoyl phosphate compartmentation in Neurospora: histochemical localization of aspartate and ornithine transcarbamoylases.
Topics: Aspartic Acid; Carbamates; Cell Nucleus; Genetics, Microbial; Histocytochemistry; Lead; Microscopy, Electron; Mitochondria; Mutation; Neurospora; Neurospora crassa; Ornithine Carbamoyltransferase; Phosphates; Phosphoric Acids; Staining and Labeling; Transferases | 1972 |
Production of lesions in various tissues by amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamates; Dermatitis, Contact; Erythema; Glutamates; Guinea Pigs; Haplorhini; Histidine; Injections, Intraperitoneal; Intestines; Kidney; Liver; Macaca; Ornithine; Rabbits; Tyrosine | 1973 |
Aspartate transcarbamylase from Streptococcus faecalis. Reverse reaction and binding studies.
Topics: Acetates; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamates; Carbon Radioisotopes; Citrulline; Cyanates; Enterococcus faecalis; Enzyme Activation; Isotope Labeling; Organophosphorus Compounds; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Potassium; Protein Binding; Sodium; Succinates; Ultrafiltration | 1974 |
Pyrimidine biosynthesis de novo in skin.
Topics: Animals; Animals, Newborn; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Cytosine Nucleotides; Depression, Chemical; Hydrogen-Ion Concentration; In Vitro Techniques; Methods; Orotic Acid; Perchlorates; RNA; Skin; Solubility; Uracil; Uracil Nucleotides | 1970 |
Carbamyl phosphate synthesis in a land snail, Strophocheilus oblongus.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Centrifugation, Density Gradient; Citrulline; Cytoplasm; Electron Transport Complex IV; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Microscopy, Electron; Mitochondria; Nucleotides; Ornithine; Ornithine Carbamoyltransferase; Phosphoric Acids; Phosphotransferases; Pyrimidines; Snails; Transferases | 1970 |
Spin-labeling studies of aspartate transcarbamylase. I. Effects of nucleotide binding and subunit separation.
Topics: Adenosine Triphosphate; Aspartic Acid; Benzoates; Carbamates; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Cytosine Nucleotides; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Hydrogen-Ion Concentration; Mercury; Nucleotides; Organometallic Compounds; Piperidines; Protein Binding; Succinates; Transferases; Uracil Nucleotides | 1970 |
Reaction of the catalytic subunit of Escherichia coli aspartate transcarbamylase with permanganate ion, a reactive structural analogue of phosphate ion.
Topics: Aspartic Acid; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Cysteine; Diphosphates; Escherichia coli; Mercaptoethanol; Oxidation-Reduction; Phosphates; Potassium Permanganate; Succinates; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfonic Acids; Transferases | 1971 |
Comparative study of metabolic profiles of primary hepatoma, regenerating liver, and liver in newborn Swiss mice.
Topics: Acetates; Aldehyde-Lyases; Amides; Animals; Animals, Newborn; Aspartic Acid; Carbamates; Carcinoma, Hepatocellular; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Lactates; Liver; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Ornithine Carbamoyltransferase; Phosphoric Monoester Hydrolases; Transferases | 1971 |
Aspartate transcarbamylases of Citrobacter freundii.
Topics: Adenosine Triphosphate; Aspartic Acid; Carbamates; Centrifugation, Density Gradient; Chloromercuribenzoates; Chromatography, Gel; Cytidine; Cytosine; Cytosine Nucleotides; Diphosphates; Enzyme Activation; Escherichia; Guanosine Triphosphate; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Macromolecular Substances; Molecular Weight; Pentosephosphates; Phosphates; Phosphoric Acids; Ribose; Transferases; Uracil Nucleotides | 1971 |
Progressive changes in the enzyme levels of mouse foetal liver.
Topics: Animals; Arginase; Aspartic Acid; Carbamates; Female; Fetus; Fructose; Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase; Gestational Age; Glucose-6-Phosphatase; Liver; Mice; Pregnancy; Transferases | 1971 |
Specific repression of phosphoribosylpyrophosphate synthetase by uridine compounds in Salmonella typhimurium.
Topics: Adenosine Triphosphate; Aspartic Acid; Carbamates; Cytidine; Enzyme Repression; Genetics, Microbial; Mutation; Pentosephosphates; Phosphoric Acids; Phosphotransferases; Salmonella typhimurium; Transferases; Uridine | 1972 |
Purification and characteristics of aspartate transcarbamylase from Pseudomonas fluorescens.
Topics: Aspartic Acid; Binding Sites; Carbamates; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography; Cytosine Nucleotides; Diphosphates; Electrophoresis, Disc; Hydroxyapatites; Kinetics; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Phosphates; Protein Denaturation; Pseudomonas; Pseudomonas fluorescens; Ribonucleotides; Sodium Dodecyl Sulfate; Transferases; Ultracentrifugation | 1972 |
Initial steps in the de novo pyrimidine biosynthesis in Ascaris suum.
Topics: Adenosine Triphosphate; Animals; Ascaris; Aspartate Carbamoyltransferase; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; Cytoplasm; Cytosine Nucleotides; Female; Hydrogen-Ion Concentration; Intestines; Maleates; Mitochondria; Ornithine; Ornithine Carbamoyltransferase; Ovary; Phosphates; Phosphotransferases; Pyrimidines; Stereoisomerism; Temperature | 1973 |
Aspartate transcarbamylase from Streptococcus faecalis. Steady-state kinetic analysis.
Topics: Acetates; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Binding, Competitive; Carbamates; Carbon Radioisotopes; Catalysis; Diphosphates; Enterococcus faecalis; Enzyme Activation; Feedback; Kinetics; Maleates; Models, Chemical; Organophosphorus Compounds; Protein Binding | 1974 |
Evidence from the control of pyrimidine biosynthesis in tissue minces by purines.
Topics: Adenosine; Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Chickens; Guanosine; In Vitro Techniques; Male; Mammary Glands, Animal; Organ Specificity; Organophosphorus Compounds; Orotic Acid; Oviducts; Phosphotransferases; Rats; Time Factors; Uridine | 1974 |
N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Ion Exchange; Fibroblasts; Haplorhini; Kidney; Kinetics; Mice; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Simian virus 40; Species Specificity; Time Factors; Tritium; Uridine | 1974 |
Yolk sac fluid and yolk sac membrane enzymes in the marsupial, Macropus eugenii.
Topics: Animals; Arginine; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell Membrane; Chromatography, Paper; Chromatography, Thin Layer; Citric Acid Cycle; Citrulline; Egg Yolk; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Female; Fumarates; Glucose; Glucosephosphate Dehydrogenase; Glutamates; Glycolysis; Ketoglutaric Acids; L-Lactate Dehydrogenase; Malate Dehydrogenase; Malates; Marsupialia; Ornithine Carbamoyltransferase; Ovum; Pyruvates; Succinates | 1974 |
Carbamyl phosphate and glutamine stimulation of the gallbladder salt pump.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Azaserine; Bicarbonates; Biological Transport, Active; Carbamates; Gallbladder; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; Organophosphorus Compounds; Rabbits; Sodium Chloride; Water | 1974 |
Regulation of orotidylic acid pyrophosphorylase in Saccharomyces cerevisiae.
Topics: Amidohydrolases; Amino Acids; Aspartic Acid; Carbamates; Carboxy-Lyases; Cell-Free System; Culture Media; Enzyme Induction; Enzyme Repression; Fluorouracil; Genes; Genetic Complementation Test; Genetics, Microbial; Mutation; Orotic Acid; Oxidoreductases; Pentosyltransferases; Pyrimidines; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry; Transferases; Uracil; Uracil Nucleotides | 1972 |
Ureidosuccinic acid uptake in yeast and some aspects of its regulation.
Topics: Amino Acids; Ammonium Sulfate; Aspartic Acid; Canavanine; Carbamates; Carbon Isotopes; Citrulline; Culture Media; Drug Resistance, Microbial; Genetic Complementation Test; Genetics, Microbial; Membrane Transport Proteins; Mutation; Phenotype; Proline; Pyrimidines; Saccharomyces; Saccharomyces cerevisiae | 1972 |
A role for zinc in the quaternary structure of aspartate transcarbamylase from Escherichia coli.
Topics: Aspartic Acid; Binding Sites; Cadmium; Carbamates; Carbon Isotopes; Centrifugation, Zonal; Chelating Agents; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Drug Stability; Electrophoresis; Escherichia coli; Macromolecular Substances; Mercury; Mercury Isotopes; Protein Conformation; Spectrophotometry; Transferases; Ultracentrifugation; Ultraviolet Rays; Zinc; Zinc Isotopes | 1972 |
Aspartate transcarbamylase is not a ping-pong enzyme.
Topics: Aspartic Acid; Carbamates; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Phosphoric Acids; Transferases | 1972 |
Restoration of a single enzyme function in bifunctionally defective non-polar pyrimidine-3 mutants of Neurospora.
Topics: Acridines; Alleles; Arginine; Aspartic Acid; Bacteriological Techniques; Carbamates; Genetic Code; Genetic Complementation Test; Hydroxylamines; Models, Biological; Mutagens; Mutation; Neurospora; Nitrites; Nitrosoguanidines; Phosphotransferases; Pyrimidines; Transferases | 1972 |
Conformational changes in aspartate transcarbamylase. IV. Ligand effects on intersubunit interactions.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartic Acid; Binding Sites; Carbamates; Chromatography, Gel; Cytosine Nucleotides; Drug Stability; Escherichia coli; Hot Temperature; Macromolecular Substances; Models, Structural; Phosphates; Phosphoric Acids; Protein Binding; Protein Conformation; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Transferases | 1972 |
A model for nucleotide regulation of aspartate transcarbamylase.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Aspartic Acid; Binding Sites; Carbamates; Cytidine; Cytosine; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Guanosine Triphosphate; Inosine; Inosine Nucleotides; Kinetics; Mathematics; Models, Chemical; Nucleotides; Phosphoric Acids; Protein Conformation; Radioisotopes; Transferases | 1972 |
A nuclear magnetic resonance study of the binding of substrate analogues to a modified aspartate transcarbamylase.
Topics: Acetates; Aspartic Acid; Binding Sites; Carbamates; Deuterium; Escherichia coli; Magnetic Resonance Spectroscopy; Mathematics; Mercury; Nitrophenols; Organometallic Compounds; Phosphoric Acids; Protein Binding; Succinates; Sulfhydryl Reagents; Transferases | 1972 |
The dual genetic control of ornithine carbamolytransferase in Escherichia coli. A case of bacterial hybrid enzymes.
Topics: Aspartic Acid; Biological Evolution; Carbamates; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Escherichia coli; Genes; Genetics, Microbial; Isoenzymes; Macromolecular Substances; Molecular Biology; Molecular Weight; Ornithine; Ornithine Carbamoyltransferase; Sodium Dodecyl Sulfate; Transferases | 1972 |
Electron microscopy of aspartate transcarbamylase and its catalytic subunit.
Topics: Aspartic Acid; Carbamates; Escherichia coli; Macromolecular Substances; Microscopy, Electron; Transferases | 1972 |
Structure and arrangement of the regulatory subunits in aspartate transcarbamylase.
Topics: Alkylation; Allosteric Regulation; Apoproteins; Aspartic Acid; Carbamates; Carbon Isotopes; Catalysis; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Cytosine Nucleotides; Electrophoresis, Disc; Escherichia coli; Imides; Macromolecular Substances; Mercury; Models, Structural; Optical Rotatory Dispersion; Pimelic Acids; Prednisone; Sodium Dodecyl Sulfate; Sulfhydryl Reagents; Ultracentrifugation; Ultraviolet Rays; Zinc | 1972 |
Genetic control of the arginine pathways in Aspergillus nidulans. Common regulation of anabolism and catabolism.
Topics: Arginase; Arginine; Aspartate Carbamoyltransferase; Aspartic Acid; Aspergillus; Aspergillus nidulans; Carbamates; Enzyme Repression; Genes, Regulator; Keto Acids; Mutation; Ornithine; Phosphates; Proline; Transaminases | 1972 |
Carbamyl phosphate binding to aspartate transcarbamylase. Partial saturation and its alteration by succinate.
Topics: Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamates; Carbon Isotopes; Catalysis; Dialysis; Escherichia coli; Isotope Labeling; Organophosphorus Compounds; Phosphoric Acids; Phosphorus Isotopes; Structure-Activity Relationship; Succinates; Zinc | 1973 |
Aspartate transcarbamylase. A study of possible roles for the sulfhydryl group at the active site.
Topics: Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Benzoates; Binding Sites; Carbamates; Catalysis; Chemical Phenomena; Chemistry; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Ligands; Macromolecular Substances; Nitro Compounds; Organophosphonates; Organophosphorus Compounds; Oxidation-Reduction; Potassium Permanganate; Protein Conformation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds; Ultracentrifugation | 1973 |
Mechanism of the reaction catalyzed by the catalytic subunit of aspartate transcarbamylase. Kinetic studies with carbamyl phosphate as substrate.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Binding, Competitive; Carbamates; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Escherichia coli; Isotope Labeling; Kinetics; Mathematics; Mercuribenzoates; Organophosphorus Compounds; Phosphates; Phosphorus Radioisotopes; Protein Binding; Succinates; Time Factors; Tritium; Trypsin | 1973 |
Mechanism of the reaction catalyzed by the catalytic subunit of aspartate transcarbamylase. Kinetic studies with acetyl phosphate as substrate.
Topics: Acetates; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Binding, Competitive; Carbamates; Carbon Radioisotopes; Escherichia coli; Kinetics; Mathematics; Organophosphorus Compounds; Phosphates; Protein Binding; Succinates; Time Factors | 1973 |
Ordered substrate binding and evidence for a thermally induced change in mechanism for E. coli aspartate transcarbamylase.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Calorimetry; Carbamates; Carbon Radioisotopes; Chromatography, Ion Exchange; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Organophosphorus Compounds; Phosphorus Radioisotopes; Protein Binding; Temperature; Thermodynamics; Time Factors | 1974 |
A regulatory interaction between pyrimidine and purine biosyntheses via ureidosuccinic acid.
Topics: Adenine; Aspartic Acid; Carbamates; Cytosine; Drug Resistance, Microbial; Mutation; Orotic Acid; Phenotype; Purines; Pyrimidines; Saccharomyces cerevisiae; Uracil | 1974 |
Transport of glutamate in rat-liver mitochondria.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Carbamates; Carbon Isotopes; Cyanides; Ethylmaleimide; Glutamates; Hydrazones; In Vitro Techniques; Ketoglutaric Acids; Malates; Membranes; Mitochondria, Liver; Mitochondrial Swelling; Organomercury Compounds; Osmosis; Oxidation-Reduction; Oxygen Consumption; Rats; Rotenone; Succinates; Valinomycin | 1972 |
The effects of enzyme synthesis and stability and of deoxyribonucleic acid replication on the cellular levels of aspartate transcarbamylase during the cell cycle of eucaryote Chlorella.
Topics: Ammonium Sulfate; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Cell Division; Centrifugation, Density Gradient; Chlorella; Chlorophyta; Chromatography, Gel; DNA Replication; Drug Stability; Feedback; Genes; Hot Temperature; Hydrogen-Ion Concentration; Molecular Weight; Periodicity; Phosphoric Acids; RNA; Ultrafiltration; Uracil Nucleotides | 1973 |
Estimation of micro amounts of urea and carbamyl derivatives.
Topics: Alanine; Aspartic Acid; Butanones; Carbamates; Citrulline; Colorimetry; Evaluation Studies as Topic; Glutamates; Methods; Microchemistry; Oximes; Urea | 1973 |
DEAE paper chromatography to separate intermediates of the pyrimidine biosynthetic pathway and to assay asparatate transcarbamylase and dihydroorotase activities.
Topics: Amidohydrolases; Aspartate Carbamoyltransferase; Aspartic Acid; Autoradiography; Carbamates; Carbon Isotopes; Chlorella; Chlorophyta; Chromatography, DEAE-Cellulose; Chromatography, Paper; Kinetics; Methods; Nucleotides; Orotic Acid; Uridine | 1973 |
Control of pyrimidine biosynthesis in human lymphocytes. Inhibition of pyrimidine biosynthesis de novo in phytohemagglutinin-stimulated lymphocytes by external uridine and its inhibition mechanism.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Azauridine; Bicarbonates; Carbamates; Carbon Dioxide; Carbon Isotopes; Humans; Lectins; Lymphocytes; Nucleic Acids; Phosphoric Acids; Phosphotransferases; Pyrimidines; Tritium; Uracil Nucleotides; Uridine | 1973 |
Wheat-germ aspartate transcarbamoylase. The effects of ligands on the inactivation of the enzyme by trypsin and denaturing agents.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Chromatography, Gel; Dicarboxylic Acids; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Ligands; Organophosphorus Compounds; Plants; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Time Factors; Triticum; Trypsin; Trypsin Inhibitors; Uracil Nucleotides | 1973 |
Detection of the feedback control of pyrimidine biosynthesis in slices of several rat tissues.
Topics: Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Depression, Chemical; Feedback; Female; Kidney; Liver; Mammary Glands, Animal; Organophosphorus Compounds; Orotic Acid; Pyrimidines; Rats; Spleen; Uridine | 1973 |
Dihydroorotase from rat liver: purification, properties and regulatory role in pyrimidine biosynthesis.
Topics: Amidohydrolases; Animals; Aspartic Acid; Carbamates; Cations, Divalent; Cations, Monovalent; Chromatography, Gel; Cytosol; Female; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Organ Specificity; Orotic Acid; Purines; Pyrimidines; Rats; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Ultracentrifugation | 1974 |
Aspartate transcarbamylase from Escherichia coli. Characterization of the polypeptide chains by molecular weight, amino acid composition, and amino-terminal residues.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Carbamates; Dinitrophenols; Escherichia coli; Molecular Weight; Transferases | 1968 |
Carbamyl phosphate: an allosteric substrate for aspartate transcarbamylase of Escherichia coli.
Topics: Aspartic Acid; Binding Sites; Carbamates; Escherichia coli; Nucleotides; Phosphates; Transferases | 1968 |
The role of multiple enzymes in the regulation of branched metabolic pathways.
Topics: Aspartic Acid; Carbamates; Enterobacter; Escherichia coli; Feedback; Glutamate Dehydrogenase; Heptoses; Hydro-Lyases; Isoenzymes; L-Lactate Dehydrogenase; Ligases; Lyases; Ornithine Carbamoyltransferase; Oxidoreductases; Phosphates; Phosphotransferases | 1968 |
Aspartate transcarbamylase. Kinetic studies of the catalytic subunit.
Topics: Aspartic Acid; Binding Sites; Carbamates; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Cytosine Nucleotides; Dicarboxylic Acids; Escherichia coli; Feedback; Hydrogen-Ion Concentration; Kinetics; Phosphates; Transferases | 1969 |
Aspartate transcarbamylase. Studies of the catalytic subunit by ultraviolet difference spectroscopy.
Topics: Aspartic Acid; Binding Sites; Carbamates; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Malates; Methods; Models, Biological; Phosphates; Spectrophotometry; Stereoisomerism; Succinates; Transferases; Ultraviolet Rays | 1969 |
Response to the adenylate energy charge by Escherichia coli aspartate transcarbamylase and its catalytic subunit.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Aspartic Acid; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Cytosine Nucleotides; Energy Transfer; Escherichia coli; Feedback; Magnesium; Transferases | 1969 |
On the availability of intramitochondrial carbamoylphosphate for the extramitochondrial biosynthesis of pyrimidines.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Aspartic Acid; Bicarbonates; Biological Transport; Carbamates; Carbon Isotopes; Depression, Chemical; Drug Stability; Escherichia coli; Glycosides; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mitochondria, Liver; Ornithine; Phosphoric Acids; Pyrimidines; Rats; Solubility; Stimulation, Chemical; Transferases | 1969 |
Aspartate transcarbamylase. Stereospecific restrictions on the binding site for L-aspartate.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Fumarates; Kinetics; Malates; Maleates; Malonates; Phosphates; Stereoisomerism; Succinates; Tartrates; Transferases | 1970 |
Aspartate transcarbamylase. A study by transient nuclear magnetic resonance of the binding of succinate to the native enzyme and its catalytic subunit.
Topics: Aspartic Acid; Binding Sites; Carbamates; Escherichia coli; Kinetics; Magnetic Resonance Spectroscopy; Phosphoric Acids; Succinates; Temperature; Thermodynamics; Time Factors; Transferases | 1970 |
A study of the sulfhydryl groups of the catalytic subunit of Escherichia coli aspartate transcarbamylase. The use of enzyme--5-thio-2-nitrobenzoate mixed disulfides as intermediates in modifying enzyme sulfhydryl groups.
Topics: Alkylating Agents; Aspartic Acid; Benzoates; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Cyanides; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Mercury; Phosphates; Protein Binding; Spectrophotometry; Succinates; Sulfhydryl Compounds; Sulfides; Sulfites; Transferases; Ultraviolet Rays | 1970 |
Studies with aspartate transcarbamylase.
Topics: Alkylation; Amino Acids; Aspartic Acid; Binding Sites; Bromine; Carbamates; Centrifugation, Density Gradient; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Maleates; Phosphoric Acids; Succinates; Transferases; Urea | 1971 |
Subunit structure of aspartate transcarbamylase from Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Benzoates; Binding Sites; Cadmium; Carbamates; Catalysis; Centrifugation, Zonal; Chemical Phenomena; Chemistry; Chromatography, Gel; Cystine; Detergents; Escherichia coli; Guanidines; Hot Temperature; Mercury; Models, Structural; Molecular Weight; Organometallic Compounds; Peptides; Polymers; Protein Denaturation; Succinates; Sulfuric Acids; Transferases; Ultracentrifugation; Viscosity; Zinc | 1971 |
Relaxation spectra of aspartate transcarbamylase. Interaction of the catalytic subunit with carbamyl phosphate, succinate, and L-malate.
Topics: Aspartic Acid; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Escherichia coli; Isomerism; Kinetics; Malates; Mathematics; Mutation; Oscillometry; Phosphoric Acids; Spectrophotometry; Succinates; Temperature; Transferases | 1971 |
Aspartate transcarbamylase. The use of primary kinetic and solvent deuterium isotope effects to delineate some aspects of the mechanism.
Topics: Anhydrides; Aspartic Acid; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mathematics; Oxygen Isotopes; Transferases | 1971 |
Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate.
Topics: Aspartic Acid; Bromine; Carbamates; Chemical Phenomena; Chemistry, Physical; Cytosine Nucleotides; Escherichia coli; Hydrogen-Ion Concentration; Isomerism; Kinetics; Lithium; Malates; Mathematics; Models, Biological; Phosphoric Acids; Protein Binding; Spectrophotometry; Succinates; Temperature; Transferases | 1971 |
Relaxation spectra of aspartate transcarbamylase. I. Interaction of 5-bromocytidine triphosphate with native enzyme and regulatory subunit.
Topics: Aspartic Acid; Bromine; Carbamates; Catalysis; Cytosine Nucleotides; Electrophoresis, Disc; Escherichia coli; Kinetics; Macromolecular Substances; Mathematics; Phosphates; Protein Binding; Spectrophotometry; Succinates; Temperature; Thermodynamics; Transferases; Ultraviolet Rays | 1970 |
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid | 1970 |
Aspartate transcarbamylase. Interaction with the transition state analogue N-(phosphonacetyl)-L-aspartate.
Topics: Acetates; Aspartic Acid; Binding Sites; Carbamates; Catalysis; Chemical Phenomena; Chemistry; Drug Stability; Escherichia coli; Hydrazines; Lithium; Maleates; Mathematics; Organophosphonates; Phosphonoacetic Acid; Phosphoric Acids; Protein Binding; Protein Conformation; Spectrophotometry; Succinates; Transferases; Ultraviolet Rays | 1971 |
Biochemical studies of bacterial sporulation and germination. 23. Nucleotide metabolism during spore germination.
Topics: Amino Acids; Aspartic Acid; Bacillus megaterium; Bacterial Proteins; Carbamates; Carbon Isotopes; Chloramphenicol; Cyanates; Dactinomycin; Glycine; Kinetics; Metabolism; Nitrogen; Nucleosides; Nucleotides; RNA, Bacterial; Spores; Time Factors; Transferases | 1970 |
Streptococcus faecalis aspartate transcarbamylase. I. Purification and general properties.
Topics: Aspartic Acid; Benzoates; Carbamates; Chromatography, DEAE-Cellulose; Drug Stability; Electrophoresis, Disc; Enterococcus faecalis; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Mercury; Methods; Molecular Weight; Nucleotides; Organomercury Compounds; Organometallic Compounds; Temperature; Transferases | 1970 |
The effect of short-term changes in the external salinity on the levels of the non-protein nitrogenous compounds and the ornithine-urea cycle enzymes in Rana cancrivora.
Topics: Amino Acids; Animals; Anura; Arginase; Aspartic Acid; Carbamates; Choline; Citrulline; Female; Hypertonic Solutions; Ligases; Liver; Lysine; Male; Mannitol; Muscles; Ornithine Carbamoyltransferase; Phosphotransferases; Potassium; Ranidae; Sodium; Sucrose; Urea; Water-Electrolyte Balance | 1972 |
Increased aspartate carbamyltransferase activity in compensatory renal growth.
Topics: Animals; Aspartic Acid; Carbamates; Cell Division; Female; Kidney; Nephrectomy; Rats; Rats, Inbred Strains; Transferases | 1972 |
Alterations in hepatic pyrimidine and nucleic acid metabolism in magnesium-deficient rats.
Topics: Animals; Aspartic Acid; Body Weight; Carbamates; Carbon Isotopes; DNA; Female; Liver; Magnesium; Magnesium Deficiency; Organ Size; Proteins; Rats; Rats, Inbred Strains; Ribonucleases; RNA; Succinates; Transferases | 1972 |
Pyrimidine biosynthesis in rat brain.
Topics: Acetates; Adenosine; Ammonium Chloride; Animals; Aspartic Acid; Azauridine; Bicarbonates; Brain; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Glutamates; Glutamine; Guanosine; Liver; Male; Orotic Acid; Pyrimidines; Rats; RNA | 1972 |
Control of pyrimidine biosynthesis in rat liver by feedback inhibition of aspartate carbamoyltransferase.
Topics: Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Feedback; Kinetics; Liver; Orotic Acid; Phosphoric Acids; Pyrimidines; Rats; Transferases; Uridine | 1972 |
Metabolite distribution in cells.
Topics: Arginine; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Citrulline; Genes; Histocytochemistry; Kinetics; Mutation; Neurospora; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Phosphotransferases; Succinates; Uracil Nucleotides | 1972 |
Change in complementation patterns and enzyme activity of pyrimidine-3 mutants of Neurospora crassa by induced reversion.
Topics: Acridines; Alleles; Aspartic Acid; Carbamates; Chromosome Mapping; Genetic Complementation Test; Hydroxylamines; Molecular Biology; Mutation; Neurospora; Nitrites; Phosphotransferases; Pyrimidines; Radiation Genetics; Transferases; Ultraviolet Rays | 1971 |
Copurification of carbamoyl phosphate synthetase and aspartate transcarbamoylase from mouse spleen.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Animals; Aspartic Acid; Carbamates; Carbon Isotopes; Carbonates; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography; Dialysis; Drug Stability; Glutamine; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Male; Mice; Nucleotides; Phosphates; Phosphoric Acids; Phosphotransferases; Sodium; Spleen; Transferases | 1971 |
Initial steps in pyrimidine synthesis in Ehrlich ascites carcinoma.
Topics: Amidohydrolases; Animals; Aspartic Acid; Carbamates; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Orotic Acid; Phosphotransferases; Pyrimidines; Transferases | 1971 |
The development of urea cycle enzyme activity in the liver of foetal and neonatal rats.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; Female; Fetus; Ligases; Liver; Lyases; Ornithine Carbamoyltransferase; Phosphotransferases; Pregnancy; Rats; Succinates; Urea | 1970 |
The simultaneous estimation of orthophosphate and carbamoyl phosphate and application to the aspartate transcarbamoylase reaction.
Topics: Aspartic Acid; Carbamates; Escherichia coli; Phosphates; Transferases | 1967 |
Modified methods for the determination of carbamyl aspartate.
Topics: Alanine; Antipyrine; Arginine; Aspartic Acid; Carbamates; Citrulline; Colorimetry; Darkness; Indicators and Reagents; Methods; Oximes; Spectrophotometry; Sulfuric Acids; Time Factors; Uracil; Urea | 1969 |
Fine structural localization of aspartate carbamoyltransferase in rat liver.
Topics: Animals; Aspartic Acid; Carbamates; Endoplasmic Reticulum; Histocytochemistry; Liver; Microscopy, Electron; Microsomes, Liver; Rats; Succinates; Transferases | 1969 |
[Action of uracil aza-derivatives in Saccharomyces cervisiae. IV. Identification in acid soluble extracts of compounds reacting positively with diacetylmonoxime].
Topics: Arginine; Aspartic Acid; Autoradiography; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Citrulline; Oximes; Pyrimidines; Saccharomyces; Triazines; Uracil; Urea | 1969 |
Variations in enzyme phenotypes and their underlying genotypes among wild strains of the genus Neurospora.
Topics: Aspartic Acid; Carbamates; Crosses, Genetic; Genes; Genotype; Hybridization, Genetic; Mutation; Neurospora; Ornithine Carbamoyltransferase; Phenotype; Phosphotransferases; Recombination, Genetic; Transferases | 1970 |
Heat-induced disaggregation of a multifunctional enzyme complex catalyzing the first steps in pyrimidine biosynthesis in bakers' yeast.
Topics: Aspartic Acid; Binding Sites; Carbamates; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Feedback; Genetic Code; Models, Chemical; Molecular Weight; Phosphoric Acids; Phosphotransferases; Pyrimidines; Saccharomyces; Temperature; Time Factors; Transferases; Uracil Nucleotides | 1970 |
Induction of fatty liver by dietary carbamylaspartic acid.
Topics: Animals; Aspartic Acid; Carbamates; Cholesterol; Diet; Fatty Liver; Lipids; Liver; Nucleotides; Rats; Spectrophotometry | 1970 |
Crystalline L-aspartate beta-decarboxylase of Pseudomonas dacunhae. II. Subunit and amino acid composition.
Topics: Aspartic Acid; Carbamates; Carboxy-Lyases; Carboxypeptidases; Chloromercuribenzoates; Crystallization; Cystine; Dialysis; Guanidines; Hydantoins; Hydrazines; Lysine; Mercaptoethanol; Molecular Weight; Peptides; Pseudomonas; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Ultracentrifugation; Urea | 1970 |
Copurification of pyrimidine-specific carbamyl phosphate synthetase and aspartate transcarbamylase of Neurospora crassa.
Topics: Adsorption; Aspartic Acid; Calcium Phosphates; Carbamates; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Feedback; Methods; Molecular Weight; Neurospora; Ornithine Carbamoyltransferase; Phosphotransferases; Polysaccharides; Pyrimidines; Transferases; Uracil Nucleotides | 1970 |
Determination of the number of regulatory and catalytic sites on aspartate transcarbamylase.
Topics: Aspartic Acid; Binding Sites; Bromine; Carbamates; Catalysis; Chemical Phenomena; Chemistry; Cytosine Nucleotides; Molecular Weight; Protein Binding; Spectrum Analysis; Transferases | 1970 |
[Action of precursors of purine and pyrimidine nucleotides on hepatic lesions caused by ethionine].
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carbamates | 1970 |
Metabolic compartmentation at the molecular level: the function of a multienzyme aggregate in the pyrimidine pathway of yeast.
Topics: Arginine; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange | 1970 |
Control of pyrimidine biosynthesis in mammalian tissues. 3. Multiple forms of aspartate transcarbamoylase of mouse spleen.
Topics: Apatites; Aspartic Acid; Carbamates; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography | 1970 |
Pyrimidine-requiring suppressor mutations of arginine-3 in Neurospora and their bearing on the structure of the pyrimidine-3 locus.
Topics: Acridines; Arginine; Aspartic Acid; Carbamates; Genetic Complementation Test; Genetics, Microbial; Mutation; Neurospora; Phosphotransferases; Pyrimidines; Recombination, Genetic; Suppression, Genetic; Transferases | 1970 |
Conformational changes in aspartate transcarbamylase. 3. A functional model for allosteric behavior.
Topics: Adenosine Triphosphate; Aspartic Acid; Benzoates; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Cytosine Nucleotides | 1971 |
Evidence for two discrete carbamyl phosphate pools in Neurospora.
Topics: Arginine; Aspartic Acid; Carbamates; Carbon Isotopes | 1971 |
Aggregation states of a regulatory enzyme complex catalyzing the early steps of pyrimidine biosynthesis in bakers' yeast.
Topics: 1-Propanol; Aspartic Acid; Binding Sites; Calcium Phosphates; Carbamates; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Gel; Chromosomes, Bacterial; Diploidy; Enzyme Repression; Feedback; Genes; Genotype; Glutamine; Magnesium; Methods; Molecular Weight; Mutation; Phenotype; Protamines; Quaternary Ammonium Compounds; Saccharomyces; Species Specificity; Sulfates; Sulfuric Acids; Transferases; Ultracentrifugation; Uracil Nucleotides | 1971 |
Determination of aspartate transcarbamylase by the radioassay of carbamyl 14C-aspartate separated by high-voltage paper electrophoresis.
Topics: Aspartic Acid; Carbamates; Carbon Isotopes; Electrophoresis; Kinetics; Methods; Paper; Plants; Transferases | 1971 |
Conformational changes in proteins as measured by difference sedimentation studies. I. A technique for measuring small changes in sedimentation coefficient.
Topics: Aspartic Acid; Carbamates; Carboxypeptidases; Catalysis; Densitometry; Deuterium; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunoglobulin G; Light; Macromolecular Substances; Mathematics; Methods; Molecular Biology; Molecular Weight; Photography; Plant Viruses; Proteins; Rotation; Spectrum Analysis; Transferases; Ultracentrifugation; Viscosity | 1971 |
Conformational changes in proteins as measured by difference sedimentation studies. II. Effect of stereospecific ligands on the catalytic subunit of aspartate transcarbamylase.
Topics: Aspartic Acid; Carbamates; Catalysis; Chemical Phenomena; Chemistry; Glutarates; Mathematics; Molecular Biology; Molecular Weight; Phosphoric Acids; Succinates; Transferases; Ultracentrifugation | 1971 |
Interpretation of nonhyperbolic behavior in enzymic systems. II. Quantitative characteristics of rate and binding functions.
Topics: Aspartic Acid; Carbamates; Chemical Phenomena; Chemistry; Computers; Enzymes; Kinetics; Protein Binding; Succinates; Transferases | 1971 |
Measurement of ligand-protein binding interactions in a biphasic aqueous polymer system.
Topics: Aspartic Acid; Buffers; Carbamates; Cytosine Nucleotides; Dextrans; Dialysis; Glycols; Mathematics; Methods; Polyethylenes; Polymers; Protein Binding; Temperature; Transferases | 1971 |
Preparation of optically active N-carbamylaspartic acid.
Topics: Aspartic Acid; Carbamates; Chromatography, Paper; Spectrum Analysis | 1967 |
Genetic control of aspartate transcarbamylase by the pyr-3 locus of Neurospora crassa.
Topics: Aspartic Acid; Carbamates; Genetics, Microbial; Hydrogen-Ion Concentration; Kinetics; Mutation; Neurospora; Phosphates; Pyridines; Transferases | 1968 |
The aspartate transcarbamylase and carbamoyl phosphate synthetase of yeast: a multi-functional enzyme complex.
Topics: Adenosine Triphosphate; Aspartic Acid; Binding Sites; Carbamates; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Citrulline; Dextrans; Enzyme Repression; Feedback; Genetics, Microbial; Haploidy; Methods; Molecular Weight; Phosphotransferases; Saccharomyces; Succinates; Transferases; Uracil Nucleotides | 1969 |
Inhibition of urea cycle enzymes by aspartic acid analogues.
Topics: Animals; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; In Vitro Techniques; Ligases; Liver; Lyases; Magnesium; Male; Ornithine Carbamoyltransferase; Oxaloacetates; Oxidative Phosphorylation; Phosphates; Phosphotransferases; Rats; Succinates; Urea | 1969 |
Aspartate transcarbamylase. A nuclear magnetic resonance study of the binding of inhibitors and substrates to the catalytic subunit.
Topics: Amides; Aspartic Acid; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methods; Organophosphonates; Phosphates; Rotation; Temperature; Transferases | 1969 |
The enzymatic steps of pyrimidine biosynthesis in the unfertilized frog egg.
Topics: Ammonium Chloride; Animals; Anura; Aspartic Acid; Bicarbonates; Carbamates; Carbon Dioxide; Carbon Isotopes; Citrulline; Female; Fertilization; Glutamine; Orotic Acid; Ovary; Ovulation; Ovum; Phosphates; Phosphotransferases; Pyrimidines; Transferases; Uracil Nucleotides | 1969 |
The protective action of N-acetyl and N-carbamyl derivatives of glutamic and aspartic acids against ammonia intoxication.
Topics: Acetates; Ammonia; Ammonium Chloride; Animals; Antidotes; Aspartic Acid; Blood; Carbamates; Glutamates; Mice; Rats; Urea | 1965 |
Dihydropyrimidinase activity in pea plants.
Topics: Aminohydrolases; Aspartic Acid; Carbamates; Chemistry Techniques, Analytical; Chromatography, Paper; Hydrogen-Ion Concentration; Orotic Acid; Plants; Pyrimidines | 1965 |
Preparation of (R)-beta-hydroxyisobutyric acid from threo-3-methyl-L-aspartate.
Topics: Aspartic Acid; Carbamates; Chemical Phenomena; Chemistry; Hydroxybutyrates; Succinates | 1966 |
A sensitive and convenient micromethod for estimation of urea, citrulline, and carbamyl derivatives.
Topics: Aspartic Acid; Carbamates; Citrulline; Colorimetry; Indicators and Reagents; Microchemistry; Urea | 1966 |
Carbamylaspartate, a new agent against acute ammonia intoxication.
Topics: Ammonia; Animals; Aspartic Acid; Carbamates; Male; Mortality; Rats; Seizures | 1966 |
Synthesis of pyrimidine nucleotide precursors in human and rat small intestinal mucosa.
Topics: Animals; Aspartic Acid; Carbamates; Carbon Isotopes; Cell Division; Chromatography, Thin Layer; Humans; Intestinal Mucosa; Jejunum; Nucleotides; Orotic Acid; Pyrimidines; Rats | 1967 |
Regulation of glutamine synthetase. VI. Interactions of inhibitors for Bacillus licheniformis glutamine synthetase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Ammonium Chloride; Asparagine; Aspartic Acid; Bacillus; Carbamates; Drug Antagonism; Drug Synergism; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydroxamic Acids; Isoleucine; Kinetics; Ligases | 1967 |
Control of de novo pyrimidine biosynthesis in mammalian tissues. Levels and turnover of early intermediates in mouse spleen in vivo.
Topics: Animals; Aspartic Acid; Azauridine; Bicarbonates; Carbamates; Carbamyl Phosphate; Kinetics; Male; Mice; Orotic Acid; Phenylhydrazines; Pyrimidines; Spleen; Uridine Monophosphate | 1980 |
Tryptic cleavage of a peptide at modified aspartic acid.
Topics: Aspartic Acid; Carbamates; Indicators and Reagents; Oligopeptides; Substrate Specificity; Trypsin | 1980 |
Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2,3-diaminopropionic acid derivatives as surrogates of aspartic acid.
Topics: Alanine; Alkylation; Animals; Aspartic Acid; Benzamides; Benzamidines; Benzoates; Benzoic Acid; beta-Alanine; Carbamates; Esterases; Humans; Liver; Magnetic Resonance Spectroscopy; Oligopeptides; Piperazine; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship; Sulfonamides; Swine | 1997 |
Effects of ENA713 and CHF2819, two anti-Alzheimer's disease drugs, on rat amino acid levels.
Topics: Alzheimer Disease; Animals; Arginine; Aspartic Acid; Carbamates; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Dose-Response Relationship, Drug; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurons; Phenylcarbamates; Rats; Rats, Wistar; Rivastigmine; Synaptic Transmission; Taurine | 2001 |
Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
Topics: Amino Acid Substitution; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Asparagine; Aspartic Acid; Aspartic Acid Endopeptidases; Carbamates; Cell Line; Cell-Free System; CHO Cells; Cricetinae; Culture Media; Dipeptides; Endopeptidases; Humans; Intracellular Fluid; Isoleucine; Membrane Proteins; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Presenilin-1; Presenilin-2; Serine Proteinase Inhibitors; Threonine; Transfection; Up-Regulation; Valine | 2003 |
THE REGULATION OF PYRIMIDINE BIOSYNTHESIS IN NEUROSPORA CRASSA. I. END-PRODUCT INHIBITION AND REPRESSION OF ASPARTATE CARBAMOYLTRANSFERASE.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Enzyme Inhibitors; Metabolism; Neurospora; Neurospora crassa; Nucleosides; Phosphates; Pyrimidines; Transferases | 1964 |
ARGININE AS A PRECURSOR OF PYRIMIDINES IN STRAIN L-929 FIBROBLASTS INFECTED WITH PLEUROPNEUMONIA-LIKE ORGANISMS.
Topics: Arginase; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Connective Tissue; Fibroblasts; Glutamine; Ligases; Metabolism; Mycoplasma; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Phosphates; Phosphotransferases; Proline; Proteins; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Uracil; Urea; Ureohydrolases | 1964 |
PATHWAY OF PYRIMIDINE BIOSYNTHESIS IN PREMETAMORPHIC TADPOLES.
Topics: Alanine; Animals; Anura; Aspartic Acid; Carbamates; Carbon Isotopes; Carboxy-Lyases; Glucose; Larva; Liver; Metabolism; Metamorphosis, Biological; Orotic Acid; Phosphates; Pyrimidines; Research; RNA; Succinates; Uracil | 1964 |
A STUDY ON THE "IN VITRO" SYNTHESIS OF CITRULLINE. I. EFFECT OF SOME N-ALKYL DERIVATIVES OF ASPARTIC ACID.
Topics: Adenosine Triphosphate; Amino Acids; Ammonium Chloride; Antimetabolites; Aspartic Acid; Bicarbonates; Carbamates; Chelating Agents; Citrulline; Digestion; Esters; Glutamates; In Vitro Techniques; Ions; Liver; Magnesium; Ornithine; Pharmacology; Phosphates; Rats; Research | 1964 |
A STUDY ON THE "IN VITRO" SYNTHESIS OF CITRULLINE. II. EFFECT OF GLUTAMIC ACID AND DERIVATIVES IN THE PRESENCE OF FUMARIC ACID.
Topics: Acetates; Amino Acids; Antimetabolites; Aspartic Acid; Carbamates; Carbon Dioxide; Citric Acid Cycle; Citrulline; Fumarates; Glutamates; Glutamic Acid; In Vitro Techniques; Liver; Pharmacology; Rats; Research | 1964 |
THE CARBAMYL PHOSPHATE CONTENT OF RABBIT BLOOD PLASMA.
Topics: Aspartic Acid; Blood Chemical Analysis; Carbamates; Carbamyl Phosphate; Esters; Phosphates; Pyrimidines; Rabbits; Research; Transferases | 1964 |
EARLY CHANGES IN PYRIMIDINE BIOSYNTHESIS AFTER PARTIAL HEPATECTOMY.
Topics: Aspartic Acid; Carbamates; Carbon Dioxide; Carboxy-Lyases; Chromatography; Dactinomycin; Glucosyltransferases; Hepatectomy; Ligases; Liver Regeneration; Metabolism; Oxidoreductases; Phosphotransferases; Pyrimidines; Rats; Research; RNA; Transferases; Uracil Nucleotides | 1965 |
[BIOSYNTHESIS OF UREA IN THE RAT. I. IN VITRO TRIALS WITH LIVER HOMOGENATES].
Topics: Adenosine Triphosphate; Amino Acids; Aspartic Acid; Carbamates; Chemistry Techniques, Analytical; Chromatography; Citrulline; Colorimetry; In Vitro Techniques; Liver; Ornithine; Rats; Research; Urea | 1965 |
INORGANIC PYROPHOSPHATE AND CELLULAR CONTROL MECHANISMS: INHIBITION OF ASPARTATE TRANSCARBAMYLASE.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Catalysis; Diphosphates; Enzyme Inhibitors; Escherichia coli; Kinetics; Research; Transferases | 1965 |
M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals.
Topics: Aminopyridines; Animals; Anthracenes; Anticonvulsants; Aspartic Acid; Carbamates; CHO Cells; Cricetinae; gamma-Aminobutyric Acid; Hippocampus; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Norepinephrine; Patch-Clamp Techniques; Phenylenediamines; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Presynaptic Terminals; Protein Subunits; Rats; Synaptosomes | 2004 |
In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbamates; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Genes, Dominant; Hepacivirus; Inhibitory Concentration 50; Kinetics; Macrocyclic Compounds; Models, Chemical; Models, Molecular; Mutation; Oligopeptides; Plasmids; Protein Structure, Tertiary; Quinolines; Serine Proteinase Inhibitors; Thiazoles; Time Factors; Viral Nonstructural Proteins | 2004 |
Synthesis of carbamate-type caged derivatives of a novel glutamate transporter blocker.
Topics: Amination; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carbamates; Cell Line; Dogs; Fluorine; Glutamic Acid; Methylation; Molecular Structure; Spectrum Analysis | 2004 |
PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Blotting, Western; Carbamates; Cell Line; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; gamma-Aminobutyric Acid; Gene Expression Regulation; Membrane Glycoproteins; Membrane Proteins; Mice; Peptide Fragments; Presenilin-1; Presenilin-2; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Radioimmunoassay; Statistics, Nonparametric; Transgenes; Triglycerides | 2004 |
In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.
Topics: Amino Acid Substitution; Amino Acids; Aspartic Acid; Binding Sites; Carbamates; Drug Resistance, Viral; Genes, Dominant; Hepacivirus; Humans; In Vitro Techniques; Inhibitory Concentration 50; Kinetics; Macrocyclic Compounds; Models, Chemical; Models, Molecular; Mutation; Oligopeptides; Quinolines; Replicon; RNA, Viral; Serine Proteinase Inhibitors; Thiazoles; Viral Nonstructural Proteins | 2005 |
Molecular cloning and biochemical characterization of L-N-carbamoylase from Sinorhizobium meliloti CECT4114.
Topics: Amidohydrolases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Carbamates; Cloning, Molecular; Coenzymes; Dimerization; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Metals; Methionine; Molecular Sequence Data; Molecular Weight; N-Formylmethionine; Recombinant Proteins; Sequence Homology, Amino Acid; Sinorhizobium meliloti; Substrate Specificity; Temperature; Tryptophan | 2005 |
Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.
Topics: Amino Acid Substitution; Aspartic Acid; Carbamates; Drug Resistance, Viral; Furans; Glutamic Acid; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Protein Binding; Sulfonamides; Thermodynamics | 2007 |
The role of OXA-1 beta-lactamase Asp(66) in the stabilization of the active-site carbamate group and in substrate turnover.
Topics: Aspartic Acid; Base Sequence; beta-Lactamases; Binding Sites; Blotting, Western; Carbamates; DNA Primers; Kinetics; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Substrate Specificity | 2008 |
Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S.
Topics: Asparagine; Aspartic Acid; Carbamates; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Viral; Furans; HIV Protease; HIV Protease Inhibitors; Humans; Hydrogen Bonding; Mutation; Nelfinavir; Sulfonamides | 2009 |
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Topics: Aspartic Acid; Carbamates; Carbon Dioxide; Glycine; Homocysteine; Ionic Liquids; Kinetics; Models, Chemical; Thermodynamics; Water | 2020 |
Insights into effect of the Asp25/Asp25' protonation states on binding of inhibitors Amprenavir and MKP97 to HIV-1 protease using molecular dynamics simulations and MM-GBSA calculations.
Topics: Aspartic Acid; Benzothiazoles; Carbamates; Furans; HIV Protease; HIV Protease Inhibitors; Molecular Dynamics Simulation; Protein Stability; Protons; Sulfonamides | 2021 |