aspartic acid has been researched along with camptothecin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Kataoka, S; Kawai, H; Mashima, T; Naito, M; Tsuruo, T | 1 |
| Kowalska-Loth, B; Staron, K; Szumiel, I | 1 |
| Beavis, RC; Berman, Y; Devi, LA; Newcomb, EW; Reed, JC; Thomas, A; Wood, DE | 1 |
| Clarke, EE; Gervais, FG; Huang, J; LeBlanc, A; Nicholson, DW; Rigby, M; Robertson, GS; Roy, S; Ruffolo, SC; Shearman, MS; Smith, D; Thornberry, NA; Vaillancourt, JP; Van Der Ploeg, LH; Xanthoudakis, S; Xu, D; Zamboni, RJ; Zheng, H; Zhu, Y | 1 |
| Arioka, H; Fukumoto, H; Fukuoka, K; Ishida, T; Iwamoto, Y; Kurokawa, H; Narita, N; Nishio, K; Saijo, N; Suzuki, T; Tomonari, A; Usuda, J | 1 |
| de, J; Kapchina, VM; Woltering, EJ; Yakimova, ET | 1 |
| Albor, A; El-Hizawi, S; Kulesz-Martin, M; Lagowski, JP | 1 |
| Ando, M; Hanioka, N; Ishida, S; Jinno, H; Nishimura, T; Ozawa, S; Saeki, M; Saito, Y; Sawada, J; Tanaka-Kagawa, T | 1 |
| Ando, M; Hanioka, N; Jinno, H; Kaniwa, N; Minami, H; Ohtsu, A; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sawada, J; Shirao, K; Tanaka-Kagawa, T; Yoshida, T | 1 |
| Kawano, K; Maitani, Y; Okano, T; Opanasopit, P; Watanabe, M; Yokoyama, M | 2 |
| Balaña-Fouce, R; Diaz-González, R; Pérez-Pertejo, Y; Pommier, Y; Reguera, RM | 1 |
| Chen, GQ; Duan, XF; Wen, DH; Zhao, M | 1 |
| Fan, N; Huang, J; Li, Y; Liu, S; Liu, Y; Wang, D; Yu, J; Zhang, W | 1 |
| Harada, Y; Kawano, K; Maitani, Y; Saiki, T; Sakai, M; Yamamoto, T; Yokoyama, M | 1 |
| Huang, H; Huang, J; Liu, S; Xu, H; Yu, J; Zeng, J | 1 |
| Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z | 1 |
| Alberts, SR; Berenberg, JL; Diasio, RB; Goldberg, RM; Lee, AM; Pavey, E; Sargent, DJ; Shi, Q; Sinicrope, FA | 1 |
| Brünner, N; Bunch, L; Christensen, S; Jensen, AA; Jensen, NF; Pedersen, SF; Pedraz-Cuesta, E; Romer, MU; Stenvang, J | 1 |
| D'Annessa, I; Dasari, JB; Fiorani, P; Messina, B; Ottaviani, A; Soren, BC; Tesauro, C; Thareparambil, A; Wang, Z | 1 |
2 trial(s) available for aspartic acid and camptothecin
| Article | Year |
|---|---|
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Choline; Creatine; Dacarbazine; Feasibility Studies; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Prognosis; Prospective Studies; Survival Rate; Temozolomide | 2013 |
DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147).
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Diarrhea; Dihydrouracil Dehydrogenase (NADP); Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Genetic Predisposition to Disease; Humans; Leucovorin; Logistic Models; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Polymorphism, Single Nucleotide; Prospective Studies; Severity of Illness Index; Thrombocytopenia; Valine; Vomiting | 2014 |
19 other study(ies) available for aspartic acid and camptothecin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells.
Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 1; Cell Cycle; Cell Line; Cysteine Endopeptidases; Cytarabine; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; Kinetics; Leukemia, Myeloid; Time Factors; Tumor Cells, Cultured | 1995 |
The sensitivity to camptothecin of DNA topoisomerase I in L5178Y-S lymphoma cells.
Topics: Animals; Aspartic Acid; Camptothecin; Drug Resistance; Leukemia L5178; Mice; Neoplasm Proteins; Potassium Chloride; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1994 |
Bax cleavage is mediated by calpain during drug-induced apoptosis.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Binding Sites; Calpain; Camptothecin; Cell Death; Cell Extracts; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; HL-60 Cells; Humans; Hydrolysis; Leucine; Molecular Sequence Data; Mutation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Substrate Specificity | 1998 |
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Topics: Acute Disease; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloidosis; Animals; Apoptosis; Aspartic Acid; Aspartic Acid Endopeptidases; Brain Diseases; Camptothecin; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Excitatory Amino Acid Agonists; Hippocampus; Humans; In Situ Nick-End Labeling; Kainic Acid; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oligopeptides; Rabbits; Rats; Rats, Wistar; Sweden; Tumor Cells, Cultured | 1999 |
Ectopic p16(ink4) expression enhances CPT-11-induced apoptosis through increased delay in S-phase progression in human non-small-cell-lung-cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aspartic Acid; Camptothecin; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase Inhibitors; Caspases; Cyclin A; Cyclin-Dependent Kinase Inhibitor p16; DNA Fragmentation; DNA, Complementary; Enzyme Activation; Gene Expression; Humans; Irinotecan; Lung Neoplasms; Protease Inhibitors; S Phase; Time Factors; Transfection; Tumor Cells, Cultured | 2000 |
A critical role for ethylene in hydrogen peroxide release during programmed cell death in tomato suspension cells.
Topics: Apoptosis; Aspartic Acid; Calcium; Calcium Channels; Camptothecin; Caspase Inhibitors; Cells, Cultured; Ethylenes; Glycine; Hydrogen Peroxide; Lanthanum; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Plant Growth Regulators; Solanum lycopersicum; Tosyllysine Chloromethyl Ketone | 2002 |
Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteins.
Topics: Aspartic Acid; Bone Neoplasms; Camptothecin; DNA Topoisomerases, Type I; Enzyme Inhibitors; Gene Amplification; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mutation; Osteosarcoma; Phenotype; Phosphonoacetic Acid; Protein Structure, Tertiary; Topoisomerase I Inhibitors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Camptothecin; Chlorocebus aethiops; COS Cells; Genetic Variation; Glucuronides; Glucuronosyltransferase; Glutamine; Glycine; Humans; Irinotecan; Proline; Tyrosine | 2003 |
Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Camptothecin; COS Cells; Exons; Genetic Variation; Glucuronates; Glucuronic Acid; Glucuronosyltransferase; Humans; Irinotecan; Japan; Mutation; Neoplasms; Polymorphism, Single Nucleotide; Transfection; UDP-Glucuronosyltransferase 1A9 | 2003 |
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting.
Topics: Antineoplastic Agents, Phytogenic; Aspartic Acid; Biopolymers; Buffers; Camptothecin; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Chromatography, High Pressure Liquid; Drug Delivery Systems; Lactones; Micelles; Phosphates; Polyethylene Glycols; Proteins; Pyrenes | 2004 |
Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Aspartic Acid; Biopolymers; Camptothecin; Drug Carriers; Drug Stability; Injections, Intravenous; Male; Mice; Micelles; Particle Size; Polyethylene Glycols; Polymers; Solubility | 2006 |
Mutational study of the "catalytic tetrad" of DNA topoisomerase IB from the hemoflagellate Leishmania donovani: Role of Asp-353 and Asn-221 in camptothecin resistance.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Base Sequence; Binding Sites; Camptothecin; Catalysis; DNA Primers; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Flagella; Leishmania donovani; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Topoisomerase I Inhibitors | 2008 |
PU.1, a novel caspase-3 substrate, partially contributes to chemotherapeutic agents-induced apoptosis in leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Mutagenesis, Site-Directed; Oligopeptides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Trans-Activators | 2009 |
Nanomicelle with long-term circulation and enhanced stability of camptothecin based on mPEGylated alpha,beta-poly (L-aspartic acid)-camptothecin conjugate.
Topics: Antineoplastic Agents, Phytogenic; Aspartic Acid; Camptothecin; Drug Compounding; Drug Stability; Micelles; Microscopy, Electron, Transmission; Models, Chemical; Molecular Structure; Nanostructures; Particle Size; Polyethylene Glycols; Polymers; Spectroscopy, Fourier Transform Infrared; Time Factors | 2010 |
Effects of organic solvents on drug incorporation into polymeric carriers and morphological analyses of drug-incorporated polymeric micelles.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Biopolymers; Camptothecin; Chemistry, Pharmaceutical; Chloroform; Drug Carriers; Drug Compounding; Kinetics; Light; Male; Mice; Micelles; Microscopy, Atomic Force; Microscopy, Polarization; Molecular Structure; Nanotechnology; Particle Size; Polyethylene Glycols; Scattering, Radiation; Solubility; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Trifluoroethanol | 2011 |
Hollow nanosphere fabricated from β-cyclodextrin-grafted α,β-poly(aspartic acid) as the carrier of camptothecin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aspartic Acid; beta-Cyclodextrins; Biopolymers; Camptothecin; Cell Survival; Cells, Cultured; Drug Carriers; Drug Compounding; Fibrosarcoma; Mice; Nanospheres; Tumor Cells, Cultured; Water | 2013 |
The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.
Topics: Amino Acid Transport System X-AG; Antineoplastic Agents; Aspartic Acid; Camptothecin; Cell Death; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Copper; Drug Resistance, Neoplasm; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Gene Expression; Gene Knockdown Techniques; Glutathione; HCT116 Cells; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Protein Transport; Tumor Suppressor Protein p53 | 2015 |
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance.
Topics: Antineoplastic Agents, Phytogenic; Aspartic Acid; Binding Sites; Camptothecin; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Glycine; Humans; Kinetics; Mutation; Proteolysis | 2019 |