Page last updated: 2024-08-17

aspartic acid and calpain

aspartic acid has been researched along with calpain in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's7 (41.18)18.2507
2000's6 (35.29)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kegerise, C; Noszek, JC; Siman, R1
Christoph, G; Siman, R1
Noszek, JC; Siman, R1
Dolle, RE; Graybill, TL; Gregory, JS; Harris, AL; Helaszek, CT; Miller, RE; Osifo, IK; Singh, J; Speier, G; Whipple, D1
Arthur, JS; Elce, JS1
Coutts, CT; Foster, J; Gyte, A; Upton, R; Widdowson, PS; Wyatt, I1
Gnegy, ME; McGinnis, KM; Wang, KK; Whitton, MM1
Beavis, RC; Berman, Y; Devi, LA; Newcomb, EW; Reed, JC; Thomas, A; Wood, DE1
Edelstein, CL; Schrier, RW; Shi, Y1
Gnegy, ME; McGinnis, KM; Mukerjee, N; Park, YH; Wang, KK1
Imajoh-Ohmi, S; Kato, M; Kikuchi, H; Maki, M; Nonaka, T1
Anderson, DK; Bausano, B; DeFord, SM; Hayes, RL; Newcomb-Fernandez, JK; Pike, BR; Ringger, NC; Shohami, E; Wang, KK; Zhao, X1
Bordone, L; Campbell, C1
Dhermy, D; Kroviarski, Y; Lecomte, MC; Nicolas, G; Rotter, B1
Cheng Liu, M; Gold, MS; Hayes, RL; Kobeissy, FH; Larner, SF; Wang, KK; Warren, MW; Zheng, W1
Chen, D; Tang, R; Yu, B; Zhang, K1
Halpin, LE; Northrop, NA; Yamamoto, BK1

Other Studies

17 other study(ies) available for aspartic acid and calpain

ArticleYear
Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:5

    Topics: Animals; Aspartic Acid; Calpain; Colchicine; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Peptide Hydrolases; Rats; Rats, Inbred Strains; Spectrin; Time Factors; Tissue Distribution

1989
beta-Amyloid precursor is a PEST protein.
    Biochemical and biophysical research communications, 1989, Dec-29, Volume: 165, Issue:3

    Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine

1989
Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo.
    Neuron, 1988, Volume: 1, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Calpain; Cytosol; Enzyme Activation; Erythrocytes; Humans; Isoenzymes; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Peptide Mapping; Rats; Rats, Inbred Strains; Spectrin; Substrate Specificity

1988
Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.
    Journal of medicinal chemistry, 1995, Jan-20, Volume: 38, Issue:2

    Topics: Aspartic Acid; Calpain; Caspase 1; Cathepsin B; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Ketones; Structure-Activity Relationship

1995
Interaction of aspartic acid-104 and proline-287 with the active site of m-calpain.
    The Biochemical journal, 1996, Oct-15, Volume: 319 ( Pt 2)

    Topics: Animals; Aspartic Acid; Calcium; Calpain; Hydrogen-Ion Concentration; Point Mutation; Proline; Protein Conformation; Rats; Substrate Specificity

1996
Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Aspartic Acid; Blotting, Western; Calpain; Cerebellum; Free Radicals; Glutamic Acid; Hydrocarbons, Chlorinated; Lipid Peroxidation; Male; Necrosis; Nervous System Diseases; Neurons; Oxidative Stress; Propionates; Rats; Spectrin

1997
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspase 3; Caspases; Chlorobenzoates; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Mice; Neuroblastoma; Peptide Fragments; Recombinant Proteins; Staurosporine; Thapsigargin; Tumor Cells, Cultured

1998
Bax cleavage is mediated by calpain during drug-induced apoptosis.
    Oncogene, 1998, Sep-03, Volume: 17, Issue:9

    Topics: Alanine; Amino Acid Sequence; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Binding Sites; Calpain; Camptothecin; Cell Death; Cell Extracts; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; HL-60 Cells; Humans; Hydrolysis; Leucine; Molecular Sequence Data; Mutation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Substrate Specificity

1998
Role of caspases in hypoxia-induced necrosis of rat renal proximal tubules.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:9

    Topics: Animals; Aspartic Acid; Calpain; Caspase 1; Caspase Inhibitors; Caspases; Coumarins; Cysteine Proteinase Inhibitors; Hypoxia; Interleukin-1; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Necrosis; Oligopeptides; Rats; Rats, Sprague-Dawley; Substrate Specificity

1999
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.
    Biochemical and biophysical research communications, 1999, Sep-16, Volume: 263, Issue:1

    Topics: Acetylcysteine; Aspartic Acid; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Humans; Marine Toxins; Oxocins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Staurosporine; Substrate Specificity

1999
Caspases cleave the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human Jurkat T cells.
    Journal of biochemistry, 2000, Volume: 127, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Calcium-Binding Proteins; Calpain; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; fas Receptor; Humans; Jurkat Cells; Leupeptins; Oligopeptides; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Tumor Necrosis Factor-alpha

2000
TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.
    Journal of neuroscience research, 2001, Apr-15, Volume: 64, Issue:2

    Topics: Animals; Apoptosis; Aspartic Acid; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Nerve Tissue Proteins; Neurons; Protein Synthesis Inhibitors; Rats; Septum Pellucidum; Spectrin; Tumor Necrosis Factor-alpha

2001
DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.
    The Journal of biological chemistry, 2002, Jul-19, Volume: 277, Issue:29

    Topics: Amino Acid Motifs; Amino Acid Substitution; Apoptosis; Aspartic Acid; Calpain; DNA Damage; DNA Ligase ATP; DNA Ligases; Humans; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Proline; Recombinant Proteins; Serine; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Xenopus Proteins

2002
AlphaII-spectrin is an in vitro target for caspase-2, and its cleavage is regulated by calmodulin binding.
    The Biochemical journal, 2004, Feb-15, Volume: 378, Issue:Pt 1

    Topics: Aspartic Acid; Binding Sites; Calmodulin; Calpain; Caspase 2; Caspases; Protein Isoforms; Spectrin; Two-Hybrid System Techniques

2004
Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure.
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Aspartic Acid; Calpain; Caspase Inhibitors; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Methamphetamine; Microfilament Proteins; Molecular Weight; N-Methyl-3,4-methylenedioxyamphetamine; N-Methylaspartate; Neurons; Peptide Fragments; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; tau Proteins; Time Factors; Vesicular Transport Proteins

2007
Effects of supplementing two levels of magnesium aspartate and transportation stress on pork quality and gene expression of micro-calpain and calpastatin of finishing pigs.
    Archives of animal nutrition, 2008, Volume: 62, Issue:5

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Calcium-Binding Proteins; Calpain; Dietary Supplements; Dose-Response Relationship, Drug; Male; Meat; Muscle, Skeletal; Random Allocation; RNA, Messenger; Stress, Psychological; Swine; Time Factors; Transportation

2008
Ammonia mediates methamphetamine-induced increases in glutamate and excitotoxicity.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:4

    Topics: Ammonia; Animals; Aspartic Acid; Body Temperature; Brain; Calpain; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Routes; Glial Fibrillary Acidic Protein; Glutamic Acid; Lactulose; Male; Methamphetamine; Molecular Weight; Rats; Rats, Sprague-Dawley; Spectrin; Time Factors

2014