Page last updated: 2024-08-17

aspartic acid and aspartimide

aspartic acid has been researched along with aspartimide in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's4 (10.53)18.2507
2000's15 (39.47)29.6817
2010's14 (36.84)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Bateman, A; Bennett, HP; Gagnon, C; Toney, K1
Karlström, A; Undén, A1
Chen, W; Ede, NJ; Jackson, DC; McCluskey, J; Purcell, AW1
Cuthbertson, A; Fischer, PM; Husbyn, M; Orning, L1
Barrow, CJ; Clippingdale, AB; Wade, JD1
Barrow, CJ; Tickler, AK; Wade, JD1
Cuthbertson, A; Husbyn, M1
Dick, F; Mergler, M; Sax, B; Vorherr, T; Weiler, P1
Dick, F; Mergler, M; Sax, B; Stähelin, C; Vorherr, T1
BIGNAMI, G; BOVET, D; BOVET-NITTI, F; MISITI, D; ROSNATI, V1
Cebrián, J; Domingo, V; Reig, F1
Dziadek, S; Kunz, H; Wagner, M1
Flora, D; Khan, MA; Mayer, JP; Mo, H; Yan, LZ1
Dick, F; Mergler, M1
Kostidis, S; Papas, S; Stathopoulos, P; Tsikaris, V1
Kaneshiro, CM; Michael, K1
Collins, JM; Cox, ZJ; Palasek, SA1
Albericio, F; Alvarez, M; Isidro-Llobet, A; Just-Baringo, X1
Ilas, J; Schlosser, G; Süli-Vargha, H1
Lewandowska, B; Mucha, P; Rekowski, P; Ruczyński, J1
Carlescu, I; Desbrieres, J; Osborn, HM; Popa, M; Scutaru, D1
Cybal, M; Kocić, I; Konstański, Z; Rekowski, P; Ruczyński, J1
Albericio, F; El-Faham, A; Subirós-Funosas, R1
Boos, I; Freund, J; Pöhner, C; Rädisch, M; Schwarzinger, S; Ullmann, V; Unverzagt, C1
Aussedat, B; Danishefsky, SJ; Vohra, Y; Wang, P1
Dölling, R; Haberkorn, U; Michels, T; Mier, W1
Dyer, FB; Garner, P; Joseph, R1
Chen, CC; Chen, KL; Lin, F; Lin, PC; Liu, XY; Rajagopal, B; Tyan, YC1
Brandstetter, H; Briza, P; Dall, E; Fegg, JC1
Behrendt, R; Huber, S; Martí, R; White, P1
Bathgate, RA; Gooley, PR; Hossain, MA; Petrie, EJ; Sethi, A; Tailhades, J; Wade, JD1
Behrendt, R; Offer, J; White, P1
Abdel-Aal, AB; Burlina, F; Offer, J; Papageorgiou, G; Quibell, M; Raz, R1
Loidl, G; Meier, T; Minuth, M; Rentsch, D; Samson, D1
Baldauf, S; Bode, JW; Farnung, J; Neumann, K1
Beiser, M; Cao, L; Elashal, HE; Koos, JD; Link, AJ; Orlova, M; Schröder, HV1
Cao, L; Elashal, HE; Link, AJ1
Alam, N; Cao, L; Do, T; Duan, J; Link, AJ; Zhu, A1

Reviews

1 review(s) available for aspartic acid and aspartimide

ArticleYear
Advances in Fmoc solid-phase peptide synthesis.
    Journal of peptide science : an official publication of the European Peptide Society, 2016, Volume: 22, Issue:1

    Topics: Amino Acids; Aspartic Acid; Cell Line; Epithelial Cells; Fluorenes; Glycosylation; Humans; Methylation; Peptides; Phosphorylation; Protein Prenylation; Protein Processing, Post-Translational; Solid-Phase Synthesis Techniques

2016

Other Studies

37 other study(ies) available for aspartic acid and aspartimide

ArticleYear
Aspartimide formation in the joining peptide sequence of porcine and mouse pro-opiomelanocortin.
    The Journal of biological chemistry, 1993, Jan-15, Volume: 268, Issue:2

    Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Endopeptidases; Erythrocytes; Male; Methylation; Mice; Mice, Inbred Strains; Molecular Sequence Data; Peptide Fragments; Pituitary Gland; Pro-Opiomelanocortin; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Substrate Specificity; Swine

1993
Design of protecting groups for the beta-carboxylic group of aspartic acid that minimize base-catalyzed aspartimide formation.
    International journal of peptide and protein research, 1996, Volume: 48, Issue:4

    Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Esters; Oligopeptides; Piperidines; Temperature; Time Factors

1996
Identification and synthesis of altered peptides modulating T cell recognition of a synthetic peptide antigen.
    Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity, 1995, Volume: 1, Issue:4

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cell Line; H-2 Antigens; Indicators and Reagents; Mice; Nitriles; Oligopeptides; T-Lymphocytes, Cytotoxic

1995
Linear analogues derived from the first EGF-like domain of human blood coagulation factor VII: enhanced inhibition of FVIIa/TF complex activity by backbone modification through aspartimide formation.
    Journal of peptide science : an official publication of the European Peptide Society, 1999, Volume: 5, Issue:7

    Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Epidermal Growth Factor; Factor VII; Humans; Molecular Sequence Data; Structure-Activity Relationship

1999
Peptide thioester preparation by Fmoc solid phase peptide synthesis for use in native chemical ligation.
    Journal of peptide science : an official publication of the European Peptide Society, 2000, Volume: 6, Issue:5

    Topics: alpha-Synuclein; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Dimethylformamide; Esters; Fluorenes; Humans; Models, Chemical; Nerve Tissue Proteins; Peptide Biosynthesis; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Synucleins; Time Factors; Triazoles

2000
Improved preparation of amyloid-beta peptides using DBU as Nalpha-Fmoc deprotection reagent.
    Journal of peptide science : an official publication of the European Peptide Society, 2001, Volume: 7, Issue:9

    Topics: Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Fluorenes; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Protein Binding; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2001
A novel approach to the synthesis of EGF-like domains: a method for the one-pot regioselective formation of the three disulfide bonds of a human blood coagulation factor VII EGF-1 analogue.
    The journal of peptide research : official journal of the American Peptide Society, 2002, Volume: 60, Issue:2

    Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; Epidermal Growth Factor; Factor VII; Humans; Molecular Sequence Data; Peptides; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2002
The aspartimide problem in Fmoc-based SPPS. Part I.
    Journal of peptide science : an official publication of the European Peptide Society, 2003, Volume: 9, Issue:1

    Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorenes; Peptides

2003
The aspartimide problem in Fmoc-based SPPS. Part II.
    Journal of peptide science : an official publication of the European Peptide Society, 2003, Volume: 9, Issue:8

    Topics: Amino Acids; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Fluorenes; Peptide Biosynthesis; Peptides; Piperidines

2003
EFFECTS OF D,1-3-PHTHALIMIDOGLUTARIMIDE AND N-PHTHALYL-D,L-ASPARTIMIDE ON RAT PREGNANCY.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Abnormalities, Drug-Induced; Animals; Aspartic Acid; Female; Humans; Imides; Pharmacology; Phthalic Acids; Pregnancy; Pregnancy, Animal; Rats; Research; Thalidomide; Toxicology

1963
Synthesis of peptide sequences related to thrombospondin: factors affecting aspartimide by-product formation.
    The journal of peptide research : official journal of the American Peptide Society, 2003, Volume: 62, Issue:6

    Topics: Amino Acid Sequence; Aspartic Acid; Cell Line, Tumor; Humans; Molecular Sequence Data; Peptides; Thrombospondins

2003
The (2-phenyl-2-trimethylsilyl)ethyl-(PTMSEL)-linker in the synthesis of glycopeptide partial structures of complex cell surface glycoproteins.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2003, Dec-15, Volume: 9, Issue:24

    Topics: Aspartic Acid; Cadherins; Diketopiperazines; Disaccharides; Fluorides; Glycopeptides; Humans; Intestinal Mucosa; Intestines; Liver; Membrane Glycoproteins; Methylene Chloride; Models, Chemical; Mucins; Piperazines; Quaternary Ammonium Compounds; Sialic Acids; Trimethylsilyl Compounds

2003
Detection and control of aspartimide formation in the synthesis of cyclic peptides.
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Aspartic Acid; Combinatorial Chemistry Techniques; Lactams; Magnetic Resonance Spectroscopy; Molecular Structure; Peptides, Cyclic; Quality Control

2005
The aspartimide problem in Fmoc-based SPPS. Part III.
    Journal of peptide science : an official publication of the European Peptide Society, 2005, Volume: 11, Issue:10

    Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorenes; Oligopeptides

2005
Alpha- and beta- aspartyl peptide ester formation via aspartimide ring opening.
    Journal of peptide science : an official publication of the European Peptide Society, 2005, Volume: 11, Issue:10

    Topics: Amino Acids; Aspartic Acid; Esters; Fluorenes; Imides; Isoaspartic Acid; Oligopeptides; Peptides; Spectrometry, Mass, Electrospray Ionization

2005
A convergent synthesis of N-glycopeptides.
    Angewandte Chemie (International ed. in English), 2006, Feb-06, Volume: 45, Issue:7

    Topics: Acylation; Amino Acids; Aspartic Acid; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Erythropoietin; Glycopeptides; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Photochemistry; Spectrometry, Mass, Electrospray Ionization

2006
Limiting racemization and aspartimide formation in microwave-enhanced Fmoc solid phase peptide synthesis.
    Journal of peptide science : an official publication of the European Peptide Society, 2007, Volume: 13, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Fluorenes; Isomerism; Microwaves; Peptides

2007
EDOTn and MIM, new peptide backbone protecting groups.
    Biopolymers, 2008, Volume: 90, Issue:3

    Topics: Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Hydrogen-Ion Concentration; Indoles; Molecular Structure; Peptides; Polymers

2008
1,4-diazepine-2,5-dione ring formation during solid phase synthesis of peptides containing aspartic acid beta-benzyl ester.
    Journal of peptide science : an official publication of the European Peptide Society, 2007, Volume: 13, Issue:11

    Topics: Aspartic Acid; Esters; Molecular Structure; Peptides, Cyclic; Piperidines

2007
Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acid.
    Journal of peptide science : an official publication of the European Peptide Society, 2008, Volume: 14, Issue:3

    Topics: Amino Acids; Aspartic Acid; Chemistry; Fluorenes; Isoaspartic Acid; Peptides

2008
Synthesis of poly(aspartimide)-based bio-glycoconjugates.
    Carbohydrate research, 2010, Jan-11, Volume: 345, Issue:1

    Topics: Antiviral Agents; Aspartic Acid; Drug Design; Glycoconjugates; N-Acetylneuraminic Acid; Polymers; Solubility; Water

2010
Aspartimide modified galanin analogue antagonizes galanin action on insulin secretion.
    Protein and peptide letters, 2010, Volume: 17, Issue:10

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Female; Galanin; Insulin; Insulin Secretion; Islets of Langerhans; Male; Molecular Sequence Data; Muscle, Smooth; Rats; Rats, Wistar; Stomach; Swine

2010
Use of Oxyma as pH modulatory agent to be used in the prevention of base-driven side reactions and its effect on 2-chlorotrityl chloride resin.
    Biopolymers, 2012, Volume: 98, Issue:2

    Topics: Aspartic Acid; Hydrogen-Ion Concentration; Hydroxylamines; Molecular Structure; Peptides; Pregnadienes; Trityl Compounds

2012
Convergent solid-phase synthesis of N-glycopeptides facilitated by pseudoprolines at consensus-sequence Ser/Thr residues.
    Angewandte Chemie (International ed. in English), 2012, Nov-12, Volume: 51, Issue:46

    Topics: Amino Acid Sequence; Aspartic Acid; Consensus Sequence; Glycopeptides; Molecular Sequence Data; Proline; Serine; Solid-Phase Synthesis Techniques; Threonine

2012
An advance in the chemical synthesis of homogeneous N-linked glycopolypeptides by convergent aspartylation.
    Angewandte Chemie (International ed. in English), 2012, Nov-12, Volume: 51, Issue:46

    Topics: Amino Acid Sequence; Aspartic Acid; Glycopeptides; Molecular Sequence Data; Solid-Phase Synthesis Techniques

2012
Acid-mediated prevention of aspartimide formation in solid phase peptide synthesis.
    Organic letters, 2012, Oct-19, Volume: 14, Issue:20

    Topics: Acids; Aspartic Acid; Hydrogen-Ion Concentration; Molecular Structure; Solid-Phase Synthesis Techniques

2012
Rapid formation of N-Glycopeptides via Cu(II)-promoted glycosylative ligation.
    Organic letters, 2013, Feb-15, Volume: 15, Issue:4

    Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Combinatorial Chemistry Techniques; Copper; Glycopeptides; Glycosylation; Lysine; Molecular Structure

2013
A mild removal of Fmoc group using sodium azide.
    Amino acids, 2014, Volume: 46, Issue:2

    Topics: Amino Acids; Angiotensin II; Aspartic Acid; Fluorenes; Insect Proteins; Scorpion Venoms; Sodium Azide; Solid-Phase Synthesis Techniques

2014
Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain.
    Angewandte Chemie (International ed. in English), 2015, Mar-02, Volume: 54, Issue:10

    Topics: Aspartic Acid; Cysteine Endopeptidases; Humans; Ligases; Models, Molecular; Protein Conformation

2015
New t-butyl based aspartate protecting groups preventing aspartimide formation in Fmoc SPPS.
    Journal of peptide science : an official publication of the European Peptide Society, 2015, Volume: 21, Issue:8

    Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Fluorenes; Molecular Structure; Peptides; Solid-Phase Synthesis Techniques

2015
Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Jan-18, Volume: 22, Issue:3

    Topics: Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Aspartic Acid; Calcium Chelating Agents; DNA, Recombinant; Humans; Ligation; Magnetic Resonance Spectroscopy; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Peptide

2016
A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation.
    Journal of peptide science : an official publication of the European Peptide Society, 2016, Volume: 22, Issue:5

    Topics: Acylation; Amides; Amino Acid Sequence; Aspartic Acid; Molecular Structure; Nitrobenzenes; Peptides; Solid-Phase Synthesis Techniques

2016
The aspartimide problem persists: Fluorenylmethyloxycarbonyl-solid-phase peptide synthesis (Fmoc-SPPS) chain termination due to formation of N-terminal piperazine-2,5-diones.
    Journal of peptide science : an official publication of the European Peptide Society, 2019, Volume: 25, Issue:7

    Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Fluorenes; Molecular Structure; Peptides; Piperazines; Solid-Phase Synthesis Techniques

2019
Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups.
    Nature communications, 2020, 02-20, Volume: 11, Issue:1

    Topics: Aspartic Acid; Carboxylic Acids; Cyanides; Lipoproteins, LDL; Peptides; Protein Folding; Solid-Phase Synthesis Techniques; Ubiquitin

2020
Cellulonodin-2 and Lihuanodin: Lasso Peptides with an Aspartimide Post-Translational Modification.
    Journal of the American Chemical Society, 2021, 08-04, Volume: 143, Issue:30

    Topics: Aspartic Acid; Bacillales; Peptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Thermobifida

2021
Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin.
    Biochemistry, 2023, 02-07, Volume: 62, Issue:3

    Topics: Aspartic Acid; Hydrolysis; Kinetics; Peptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase

2023
Genome Mining and Discovery of Imiditides, a Family of RiPPs with a Class-Defining Aspartimide Modification.
    Journal of the American Chemical Society, 2023, 08-30, Volume: 145, Issue:34

    Topics: Algorithms; Aspartic Acid; Biological Products; Methyltransferases

2023