Page last updated: 2024-08-17

aspartic acid and acivicin

aspartic acid has been researched along with acivicin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's6 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abanobi, SE; Laconi, E; Rajalakshmi, S; Rao, PM; Sarma, DS; Vasudevan, S1
Ardalan, B; Jayaram, HN; Johnson, RK1
Cooney, DA; Jayaram, HN; Kensler, TW1
Kufe, DW; Loh, E1
Cooney, DA; Kensler, TW; Reck, LJ1
Mu, X; Welbourne, TC1
Nelson, J; Qureshi, IA; Sarma, DS; Vasudevan, S1
Li, X; Orwar, O; Revesjö, C; Sandberg, M1
Chevalier, D; Mu, X; Welbourne, TC1
Cory, AH; Cory, JG1
Huang, Q; Lau, SS; Monks, TJ1
Peters, GJ1

Other Studies

12 other study(ies) available for aspartic acid and acivicin

ArticleYear
Effect of glycine on the induction of orotic aciduria and urinary bladder tumorigenesis in the rat.
    Toxicologic pathology, 1987, Volume: 15, Issue:2

    Topics: Ammonium Chloride; Animals; Aspartic Acid; Cycloheximide; Glycine; Isoxazoles; Male; Orotic Acid; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1987
Collateral sensitivity to N-(phosphonacetyl)-L-aspartic acid in a line of P388 leukemia cells selected for resistance to L-(alpha S, 5S)-alpha-amino-3- chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Adenine Phosphoribosyltransferase; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Ammonia); Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Isoxazoles; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Oxazoles; Phosphonoacetic Acid; Purines; Pyrimidines

1983
Effects of acivicin and PALA, singly and in combination, on de novo pyrimidine biosynthesis.
    Advances in enzyme regulation, 1982, Volume: 20

    Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Isoxazoles; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nucleic Acids; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines

1982
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspartic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Deoxyribonucleosides; Drug Synergism; Glycine; Isoxazoles; Leukemia L1210; Mice; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Ribonucleosides

1981
Therapeutic effects of acivicin and N-(phosphonacetyl)-L-aspartic acid in a biochemically designed trial against a N-(phosphonacetyl)-L-aspartic acid-resistant variant of the Lewis lung carcinoma.
    Cancer research, 1981, Volume: 41, Issue:3

    Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma; Drug Therapy, Combination; Glycine; Isoxazoles; Ligases; Lung Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Rats

1981
Extracellular glutamate flux regulates intracellular glutaminase activity in LLC-PK1-F+ cells.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Animals; Aspartic Acid; Cell Line; Extracellular Space; gamma-Glutamyltransferase; Glutamic Acid; Glutaminase; Glutamine; Intracellular Fluid; Isoxazoles; Kidney Tubules, Proximal; Kinetics; LLC-PK1 Cells; Models, Biological; Swine

1995
The effects of various inhibitors on the regulation of orotic acid excretion in sparse-fur mutant mice (spf/Y) deficient in ornithine transcarbamylase.
    Chemico-biological interactions, 1993, Volume: 89, Issue:1

    Topics: Adenine; Animals; Antimetabolites; Aspartic Acid; Creatinine; Cycloheximide; Injections, Intraperitoneal; Isoxazoles; Liver; Male; Mice; Mice, Mutant Strains; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phosphonoacetic Acid

1993
Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition.
    Neurochemistry international, 1996, Volume: 29, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Dipeptides; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutamine; Glutathione; Hippocampus; Isoxazoles; Male; Rats; Rats, Sprague-Dawley

1996
Glutamate transport modulation of paracellular permeability across LLC-PK1-F+ monolayers.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Epithelium; gamma-Glutamyltransferase; Glucose; Glutamic Acid; Glutamine; Isoxazoles; Kidney Tubules, Proximal; Kinetics; LLC-PK1 Cells; Models, Biological; Rabbits; Swine

1996
Cellular responses in mouse leukemia L1210 cells made resistant to deoxyadenosine.
    Biochemical and biophysical research communications, 1998, Aug-28, Volume: 249, Issue:3

    Topics: Animals; Apoptosis; Aspartic Acid; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Guanosine Triphosphate; Isoxazoles; Leukemia L1210; Mice; Nucleotides; Phosphonoacetic Acid; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine.
    The Biochemical journal, 1999, Jul-01, Volume: 341 ( Pt 1)

    Topics: Animals; Aspartic Acid; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Culture Media; Cytidine; Cytidine Triphosphate; Diazooxonorleucine; DNA Damage; DNA-Binding Proteins; Epithelial Cells; Gene Expression Regulation; Glutamine; Isoxazoles; Ketoglutaric Acids; Kidney Tubules, Proximal; RNA, Messenger; Salts; Swine; Transcription Factor CHOP; Transcription Factors; Uridine

1999
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:6

    Topics: Amides; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Biphenyl Compounds; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Head and Neck Neoplasms; Humans; Isoxazoles; Naphthoquinones; Orotate Phosphoribosyltransferase; Oxidoreductases Acting on CH-CH Group Donors; Phosphonoacetic Acid; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose

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