aspartame and tyrosine

aspartame has been researched along with tyrosine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199026 (66.67)18.7374
1990's10 (25.64)18.2507
2000's1 (2.56)29.6817
2010's2 (5.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Frey, GH1
Haber, M; Koch, R; Shaw, KN; Williamson, M1
Bleicher, SJ; Flores, A; Gombos, G; Recitas, D; Shu, J; Stern, SB1
Koch, R; Schaeffler, G; Shaw, NF1
Hutsell, TC; Mares, SE; Raczialowski, FM; Ranney, RE; Schroeder, RE1
Brisson, J; Dickie, BC; Dudley, RE; Hjelle, JJ; Kotsonis, FN; Marietta, MP; Sanders, PG1
Berlin, CM; Mackey, SA1
Kernan, WJ; Mullenix, PJ; Schunior, A; Tassinari, MS1
Caccia, S; Diomede, L; Guiso, G; Romano, M; Salmona, M; Sarati, S1
Fernstrom, JD; Fernstrom, MH; Massoudi, MS1
Andersen, DW; Burgert, SL; Schedl, HP; Stegink, LD; Takeuchi, H1
Caccia, S; Diomede, L; Guiso, G; Nava, S; Romano, M; Salmona, M1
Bordet, S; Commissiong, JW; Karoum, F; Zhang, C1
Burns, TS; Hurwitz, A; Stargel, WW1
Caccia, S; Diomede, L; Guiso, G; Perego, C; Romano, M; Salmona, M1
Algeri, S; De Simoni, MG; Diomede, L; Fodritto, F; Garattini, S; Perego, C; Raimondi, L; Salmona, M1
Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE1
Ashby, J; Cochran, C; Gorman, MA; Gupta, V; Liepa, GU; Long, DL; Parker, TF1
Maher, TJ2
Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE1
Caccia, S; Garattini, S; Guiso, G; Romano, M; Salmona, M; Stasi, MA; Vezzani, A1
Baker, GL; Filer, LJ; Stegink, LD3
Maher, TJ; Pinto, JM1
Bell, EF; Filer, LJ; Stegink, LD; Ziegler, EE1
Maher, TJ; Wurtman, RJ1
Ferguson, JM1
Wurtman, RJ; Yokogoshi, H1
Caballero, B; Roberts, CH; Wurtman, RJ; Yokogoshi, H1
Ghadimi, H1
Fernstrom, JD; Fernstrom, MH; Gillis, MA1
Baker, GL; Blaskovics, ME; Filer, LJ; Koch, R; McDonnell, JE; Stegink, LD1
Filer, LJ; Renn, E; Reynolds, WA; Stegink, LD1
Carvalho, TS; da Silva, FB; da Silva, LC; Giugliani, R; Pereira, ML; Pires, RF1
Abhilash, M; Alex, M; Mathews, VV; Nair, RH1

Reviews

2 review(s) available for aspartame and tyrosine

ArticleYear
Natural food constituents and food additives: the pharmacologic connection.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:3

    Topics: Aspartame; Brain; Food Additives; Food Analysis; Humans; Neurotransmitter Agents; Nutritional Physiological Phenomena; Tryptophan; Tyrosine

1987
Neurotoxicology of food additives.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Aspartame; Blood-Brain Barrier; Dietary Carbohydrates; Dietary Proteins; Dipeptides; Emotions; Female; Food Additives; Maximum Allowable Concentration; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Seizures; Sleep Initiation and Maintenance Disorders; Tyrosine; United States; United States Food and Drug Administration

1986

Trials

9 trial(s) available for aspartame and tyrosine

ArticleYear
Use of aspartame by apparently healthy children and adolescents.
    Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Aspartame; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Dipeptides; Female; Humans; Male; Methanol; Middle Aged; Phenylalanine; Phenylpyruvic Acids; Sucrose; Tyrosine; Visual Acuity

1976
Use of aspartame in phenylketonuric heteroxygous adults.
    Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2

    Topics: Adult; Aspartame; Clinical Trials as Topic; Dipeptides; Female; Heterozygote; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Placebos; Tyrosine

1976
Administration of aspartame in non-insulin-dependent diabetics.
    Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2

    Topics: Adult; Aged; Aspartame; Blood Glucose; Diabetes Mellitus; Dipeptides; Female; Humans; Male; Middle Aged; Phenylalanine; Placebos; Tyrosine

1976
Effect of dietary aspartame on plasma concentrations of phenylalanine and tyrosine in normal and homozygous phenylketonuric patients.
    Clinical pediatrics, 1992, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Aspartame; Body Weight; Child; Female; Homozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sweetening Agents; Tyrosine

1992
Bioavailability of phenylalanine and aspartate from aspartame (20 mg/kg) in capsules and solution.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:11

    Topics: Adolescent; Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Female; Humans; Male; Osmolar Concentration; Phenylalanine; Random Allocation; Solutions; Tyrosine

1990
Effect of aspartame on plasma amino acid profiles of diabetic patients with chronic renal failure.
    The American journal of clinical nutrition, 1989, Volume: 49, Issue:6

    Topics: Amino Acids; Aspartame; Diabetic Nephropathies; Dipeptides; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine

1989
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
    The Journal of nutrition, 1987, Volume: 117, Issue:11

    Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine

1987
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults.
    Metabolism: clinical and experimental, 1988, Volume: 37, Issue:3

    Topics: Adult; Amino Acids; Aspartame; Beverages; Biological Transport; Brain; Dietary Proteins; Dipeptides; Female; Humans; Male; Phenylalanine; Tyrosine

1988
Plasma amino acid concentrations in normal adults administered aspartame in capsules or solution: lack of bioequivalence.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:5

    Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Dipeptides; Female; Humans; Kinetics; Male; Phenylalanine; Solutions; Tyrosine

1987

Other Studies

28 other study(ies) available for aspartame and tyrosine

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Results of loading doses of aspartame by two phenylketonuric (PKU) children compared with two normal children.
    Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2

    Topics: Adolescent; Aspartame; Child; Dipeptides; Female; Glutamine; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine

1976
The phenylalanine and tyrosine contnet of maternal and fetal body fluids from rabbits fed aspartame.
    Toxicology and applied pharmacology, 1975, Volume: 32, Issue:2

    Topics: Amino Acids; Amniotic Fluid; Animals; Aspartame; Body Fluids; Body Weight; Dipeptides; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rabbits; Tyrosine

1975
Plasma concentrations and pharmacokinetics of phenylalanine in rats and mice administered aspartame.
    Pharmacology, 1992, Volume: 44, Issue:1

    Topics: Administration, Oral; Amino Acids; Animals; Aspartame; Humans; Male; Mice; Mice, Inbred ICR; Phenylalanine; Random Allocation; Rats; Rats, Inbred Strains; Tyrosine

1992
No change in spontaneous behavior of rats after acute oral doses of aspartame, phenylalanine, and tyrosine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:3

    Topics: Animals; Aspartame; Behavior, Animal; Central Nervous System; Data Interpretation, Statistical; Dextroamphetamine; Male; Motor Activity; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine

1991
Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:12

    Topics: Animals; Aspartame; Brain; Drug Interactions; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Tyrosine

1991
In vivo tyrosine hydroxylation in rat retina: effect of aspartame ingestion in rats pretreated with p-chlorophenylalanine.
    The American journal of clinical nutrition, 1991, Volume: 53, Issue:4

    Topics: Animals; Aspartame; Dihydroxyphenylalanine; Fenclonine; Hydroxylation; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Retina; Tyrosine

1991
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6

    Topics: Animals; Aspartame; Aspartic Acid; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver Circulation; Methanol; Perfusion; Phenylalanine; Swine; Tyrosine

1991
Interspecies and interstrain studies on the increased susceptibility to metrazol-induced convulsions in animals given aspartame.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:2

    Topics: Animals; Aspartame; Brain; Drug Synergism; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Tyrosine

1991
Effect of precursors on the synthesis of catecholamines and on neurotransmission in the superior cervical ganglion of the rat.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Animals; Aspartame; Catecholamines; Dipeptides; Dopamine; Electric Stimulation; Ganglia, Sympathetic; Levodopa; Male; Nialamide; Norepinephrine; Rats; Rats, Inbred Strains; Synaptic Transmission; Tyrosine

1990
Plasma and brain kinetics of large neutral amino acids and of striatum monoamines in rats given aspartame.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:5

    Topics: Animals; Aspartame; Biogenic Monoamines; Corpus Striatum; Dipeptides; Phenylalanine; Rats; Rats, Inbred Strains; Time Factors; Tyrosine

1990
Aspartame and the rat brain monoaminergic system.
    Toxicology letters, 1988, Volume: 44, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartame; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Hippocampus; Hydroxyindoleacetic Acid; Nucleus Accumbens; Phenylalanine; Plasma; Rats; Serotonin; Tyrosine

1988
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4

    Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine

1989
Effect of aspartame on seizures in various models of experimental epilepsy.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:3

    Topics: Animals; Aspartame; Brain Chemistry; Dipeptides; Electroshock; Epilepsy; Male; Pentylenetetrazole; Phenylalanine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tyrosine

1988
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice.
    Neuropharmacology, 1988, Volume: 27, Issue:1

    Topics: Animals; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Drug Synergism; Flurothyl; Male; Mice; Pentylenetetrazole; Phenylalanine; Seizures; Tyrosine

1988
Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note.
    Journal of neural transmission, 1987, Volume: 70, Issue:1-2

    Topics: Administration, Oral; Animals; Aspartame; Dipeptides; Humans; Mice; Phenylalanine; Rodentia; Tyrosine

1987
Interaction of aspartame and carbohydrates in an eating-disordered patient.
    The American journal of psychiatry, 1985, Volume: 142, Issue:2

    Topics: Adult; Aspartame; Brain Chemistry; Dietary Carbohydrates; Dipeptides; Drug Interactions; Feeding and Eating Disorders; Female; Headache; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Tyrosine

1985
Acute effects of oral or parenteral aspartame on catecholamine metabolism in various regions of rat brain.
    The Journal of nutrition, 1986, Volume: 116, Issue:3

    Topics: Administration, Oral; Amino Acids; Animals; Aspartame; Body Weight; Brain; Catecholamines; Chromatography, High Pressure Liquid; Dipeptides; Injections, Intraperitoneal; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity; Tyrosine

1986
Effect of aspartame loading on plasma and erythrocyte free amino acid concentrations in one-year-old infants.
    The Journal of nutrition, 1983, Volume: 113, Issue:8

    Topics: Adult; Age Factors; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Erythrocytes; Glutamates; Glutamic Acid; Humans; Infant; Phenylalanine; Tyrosine

1983
Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles.
    The American journal of clinical nutrition, 1984, Volume: 40, Issue:1

    Topics: Amino Acids; Animals; Aspartame; Brain; Dipeptides; Drug Interactions; Glucose; Hydroxyindoleacetic Acid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine

1984
Amino acids and obesity.
    Pediatric annals, 1984, Volume: 13, Issue:7

    Topics: Amino Acids; Amino Acids, Branched-Chain; Appetite Depressants; Arginine; Aspartame; Cysteine; Humans; Obesity; Tryptophan; Tyrosine

1984
Acute effects of aspartame on large neutral amino acids and monoamines in rat brain.
    Life sciences, 1983, Apr-04, Volume: 32, Issue:14

    Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Aspartame; Brain; Catecholamines; Dipeptides; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine

1983
Levels of free amino acids in lactating women following ingestion of the sweetener aspartame.
    Nutrition reviews, 1980, Volume: 38, Issue:5

    Topics: Adult; Aspartame; Dipeptides; Female; Humans; Lactation; Lactose; Phenylalanine; Pregnancy; Tyrosine

1980
Plasma and erythrocyte concentrations of free amino acids in adult humans administered abuse doses of aspartame.
    Journal of toxicology and environmental health, 1981, Volume: 7, Issue:2

    Topics: Adult; Alanine; Alanine Transaminase; Amino Acids; Aspartame; Aspartate Aminotransferases; Dipeptides; Erythrocytes; Female; Humans; Male; Phenylalanine; Plasma; Tyrosine

1981
Plasma phenylalanine levels in phenylketonuric heterozygous and normal adults administered aspartame at 34 mg/kg body weight.
    Toxicology, 1981, Volume: 20, Issue:1

    Topics: Adult; Aspartame; Aspartic Acid; Dipeptides; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sex Factors; Tyrosine

1981
Aspartame administration to the infant monkey: hypothalamic morphology and plasma amino acid levels.
    The Anatomical record, 1980, Volume: 198, Issue:1

    Topics: Amino Acids; Animals; Aspartame; Aspartic Acid; Dipeptides; Female; Glutamates; Hypothalamus; Macaca; Macaca fascicularis; Macaca mulatta; Male; Phenylalanine; Sodium Glutamate; Tyrosine

1980
Aspartame loading test in PKU heterozygous individuals bearing severe and moderate mutations.
    Clinical genetics, 2000, Volume: 58, Issue:1

    Topics: Aspartame; DNA; DNA Mutational Analysis; Heterozygote; Humans; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine

2000
Chronic Effect of Aspartame on Ionic Homeostasis and Monoamine Neurotransmitters in the Rat Brain.
    International journal of toxicology, 2014, Volume: 33, Issue:4

    Topics: Animals; Apoptosis; Aspartame; Cerebral Cortex; Corpus Striatum; Dopamine Antagonists; Male; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Non-Nutritive Sweeteners; Phenylalanine; Random Allocation; Rats, Wistar; Serotonin Antagonists; Sodium-Potassium-Exchanging ATPase; Toxicity Tests, Chronic; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase; Water-Electrolyte Imbalance

2014