aspartame and methanol

aspartame has been researched along with methanol in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (40.54)	18.7374
1990's	5 (13.51)	18.2507
2000's	9 (24.32)	29.6817
2010's	6 (16.22)	24.3611
2020's	2 (5.41)	2.80

Authors

Authors	Studies
Frey, GH	1
Arky, RA; Brandt, K; Knopp, RH	1
McMahon, FG; Muldoon, E; Oppermann, JA; Ranney, RE	1
Andersen, DW; Burgert, SL; Schedl, HP; Stegink, LD; Takeuchi, H	1
Bell, EF; Filer, LJ; Krause, WL; Stegink, LD; Tephly, TR; Ziegler, EE	1
Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE	1
Filer, LJ; Stegink, LD	1
Bell, C; Hunninghake, DB; Leon, AS; Rassin, DK; Tephly, TR	1
Sturtevant, FM	1
London, RS	1
Franz, M	1
Airoldi, L; Cappellini, L; Davoli, E; Fanelli, R	1
Sturtevant, F	1
Sadler, MJ	1
Baker, GL; Brummel, MC; Filer, LJ; Stegink, LD	1
Baker, GL; Brummel, MC; Filer, LJ; Martin-Amat, G; McMartin, K; Stegink, LD; Tephly, TR	1
Hertelendy, ZI; Marshall, L; Mendenhall, CL; Rouster, SD; Weesner, R	1
Alemany, M; Fernández-López, JA; Pardo, R; Rafecas, I; Remesar, X; Trocho, C; Virgili, J	1
Tephly, TR	1
Akaike, N; Arata, T; Noda, K; Okano, Y; Oyama, Y; Sakai, H; Sakai, K	1
Benninger, C; Blackburn, GL; Butchko, HH; Comer, CP; de Sonneville, LM; Geha, RS; Hertelendy, Z; Koestner, A; Leon, AS; Liepa, GU; Mayhew, DA; McMartin, KE; Mendenhall, CL; Munro, IC; Novotny, EJ; Renwick, AG; Schiffman, SS; Schomer, DL; Shaywitz, BA; Spiers, PA; Stargel, WW; Tephly, TR; Thomas, JA; Trefz, FK	1
de Lourdes Cardeal, Z; Sales, JA	1
Finer, N	1
Giannoulia-Karantana, A; Schulpis, KH; Simintzi, I; Tsakiris, S	1
Angelogianni, P; Liapi, C; Schulpis, KH; Simintzi, I; Tsakiris, S	2
Bi, Y; Dong, J; Li, F; Lu, X; Shao, T; Yang, J	1
Humphries, P; Naudé, H; Pretorius, E	1
McConnell, EE; Schoeb, TR	1
Drelich, G; Górska, A; Majewska, M; Szponar, J; Tchórz, M	1
Iyyaswamy, A; Rathinasamy, S	1
Dryahina, K; Smith, D; Španěl, P; Vicherková, P	1
Miyakawa, H; Monma, K; Tahara, S; Uematsu, Y; Yamajima, Y; Yamamoto, S	1
Dapkupar, W; Iyaswamy, A; Kammella, AK; Rajan, R; Rathinasamy, S; Shanmugam, S; Thavasimuthu, C; Wankupar, W	1
Abe, I; Yokozeki, K	1
Martel, F; Rodrigues, H; Silva, C	1

Reviews

3 review(s) available for aspartame and methanol

Article	Year
Use of aspartame in pregnancy. International journal of fertility, 1985, Volume: 30, Issue:1 Topics: Aspartame; Aspartic Acid; Digestion; Dipeptides; Female; Fetus; Humans; Methanol; Phenylalanine; Pregnancy	1985
Aspartame: review of safety. Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 2 Topics: Affect; Animals; Aspartame; Behavior; Brain Neoplasms; Cognition; Drug Evaluation, Preclinical; Drug Hypersensitivity; Electroencephalography; Endocrine System; Headache; Humans; Methanol; Phenylalanine; Product Surveillance, Postmarketing; Seizures; Sweetening Agents; Weight Loss	2002
Direct and indirect cellular effects of aspartame on the brain. European journal of clinical nutrition, 2008, Volume: 62, Issue:4 Topics: Aspartame; Aspartic Acid; Brain; Humans; Methanol; Neurotransmitter Agents; Phenylalanine; Sweetening Agents	2008

Trials

6 trial(s) available for aspartame and methanol

Article	Year
Use of aspartame by apparently healthy children and adolescents. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Acne Vulgaris; Adolescent; Adult; Aspartame; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Dipeptides; Female; Humans; Male; Methanol; Middle Aged; Phenylalanine; Phenylpyruvic Acids; Sucrose; Tyrosine; Visual Acuity	1976
Effects of aspartame in young persons during weight reduction. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Adolescent; Adult; Amino Acids; Aspartame; Blood Coagulation Tests; Blood Glucose; Body Weight; Child; Clinical Trials as Topic; Diet, Reducing; Dipeptides; Female; Glucagon; Humans; Insulin; Male; Methanol; Obesity; Placebos	1976
Repeated ingestion of aspartame-sweetened beverages: further observations in individuals heterozygous for phenylketonuria. Metabolism: clinical and experimental, 1990, Volume: 39, Issue:10 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Beverages; Female; Heterozygote; Humans; Male; Methanol; Phenylalanine; Phenylketonurias	1990
Safety of long-term large doses of aspartame. Archives of internal medicine, 1989, Volume: 149, Issue:10 Topics: Adolescent; Adult; Amino Acids; Aspartame; Consumer Product Safety; Dipeptides; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Formates; Headache; Humans; Male; Methanol; Middle Aged; Random Allocation	1989
Biochemical and clinical effects of aspartame in patients with chronic, stable alcoholic liver disease. The American journal of gastroenterology, 1993, Volume: 88, Issue:5 Topics: Amino Acids; Animals; Aspartame; Drug Evaluation; Hepatic Encephalopathy; Humans; Liver; Liver Diseases, Alcoholic; Male; Methanol; Middle Aged; Milk; Phenylalanine; Risk Factors	1993
Increase of methanol in exhaled breath quantified by SIFT-MS following aspartame ingestion. Journal of breath research, 2015, Nov-19, Volume: 9, Issue:4 Topics: Adult; Aspartame; Breath Tests; Exhalation; Female; Humans; Male; Mass Spectrometry; Methanol; Middle Aged; Mouth; Time Factors; Young Adult	2015

Other Studies

28 other study(ies) available for aspartame and methanol

Article	Year
Comparative metabolism of aspartame in experimental animals and humans. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Animals; Aspartame; Aspartic Acid; Carbon Radioisotopes; Dipeptides; Dogs; Haplorhini; Humans; Methanol; Mice; Phenylalanine; Rabbits; Rats	1976
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6 Topics: Animals; Aspartame; Aspartic Acid; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver Circulation; Methanol; Perfusion; Phenylalanine; Swine; Tyrosine	1991
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4 Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine	1989
Aspartame metabolism in normal adults, phenylketonuric heterozygotes, and diabetic subjects. Diabetes care, 1989, Volume: 12, Issue:1 Topics: Adult; Aspartame; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Erythrocytes; Female; Glucagon; Heterozygote; Humans; Insulin; Lipids; Male; Methanol; Phenylalanine; Phenylketonurias; Reference Values	1989
Aspartame. Review of safety issues. Council on Scientific Affairs. JAMA, 1985, Jul-19, Volume: 254, Issue:3 Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats	1985
Saccharin and aspartame. Are they safe to consume during pregnancy? The Journal of reproductive medicine, 1988, Volume: 33, Issue:1 Topics: Aspartame; Aspartic Acid; Dipeptides; Female; Humans; Methanol; Phenylalanine; Pregnancy; Saccharin	1988
Is it safe to consume aspartame during pregnancy? A review. Nutrition update. The Diabetes educator, 1986,Spring, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aspartame; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Lactation; Male; Methanol; Phenylalanine; Pregnancy	1986
Serum methanol concentrations in rats and in men after a single dose of aspartame. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:3 Topics: Adult; Animals; Aspartame; Dipeptides; Humans; Methanol; Rats; Rats, Inbred Strains; Time Factors	1986
Does aspartame cause methanol toxicity? Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:10 Topics: Animals; Aspartame; Dipeptides; Humans; Methanol	1985
Recent aspartame studies. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:9 Topics: Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Dipeptides; Drug Interactions; Glutamates; Glutamic Acid; Humans; Infant; Methanol; Phenylalanine; Sodium Glutamate	1984
Blood methanol concentrations in one-year-old infants administered graded doses of aspartame. The Journal of nutrition, 1983, Volume: 113, Issue:8 Topics: Age Factors; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Humans; Infant; Methanol; Time Factors	1983
Blood methanol concentrations in normal adult subjects administered abuse doses of aspartame. Journal of toxicology and environmental health, 1981, Volume: 7, Issue:2 Topics: Adult; Aspartame; Dipeptides; Female; Humans; Male; Methanol	1981
Formaldehyde derived from dietary aspartame binds to tissue components in vivo. Life sciences, 1998, Volume: 63, Issue:5 Topics: Administration, Oral; Animals; Aspartame; Carbon Radioisotopes; Chromatography, Thin Layer; DNA Adducts; Formaldehyde; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Methanol; Protein Binding; Rats; Rats, Wistar	1998
Comments on the purported generation of formaldehyde and adduct formation from the sweetener aspartame. Life sciences, 1999, Volume: 65, Issue:13 Topics: Animals; Aspartame; Formaldehyde; Haplorhini; Methanol; Rats; Sweetening Agents	1999
Cytotoxic effects of methanol, formaldehyde, and formate on dissociated rat thymocytes: a possibility of aspartame toxicity. Cell biology and toxicology, 2002, Volume: 18, Issue:1 Topics: Animals; Aspartame; Calcium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Formaldehyde; Formates; Glutathione; Methanol; Rats; Rats, Wistar; T-Lymphocytes	2002
Headspace solid-phase micro-extraction gas chromatography method for the determination of methanol in aspartame sweeteners. Food additives and contaminants, 2003, Volume: 20, Issue:6 Topics: Aspartame; Beverages; Chromatography, Gas; Food Analysis; Food Contamination; Humans; Methanol	2003
Aspartame and its effects on health: approach seems simplistic in electronic responses to editorial. BMJ (Clinical research ed.), 2005, Feb-05, Volume: 330, Issue:7486 Topics: Aspartame; Formaldehyde; Formates; Health; Humans; Methanol; Phenylalanine; Sweetening Agents	2005
The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity. Pharmacological research, 2006, Volume: 53, Issue:1 Topics: Acetylcholinesterase; Adult; Aspartame; Aspartic Acid; Erythrocyte Membrane; Humans; Methanol; Phenylalanine	2006
The effect of aspartame on acetylcholinesterase activity in hippocampal homogenates of suckling rats. Pharmacological research, 2007, Volume: 56, Issue:2 Topics: Acetylcholinesterase; Animals; Animals, Suckling; Aspartame; Aspartic Acid; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Hippocampus; In Vitro Techniques; Kinetics; Methanol; Phenylalanine; Rats; Rats, Wistar; Subcellular Fractions; Sweetening Agents	2007
L-Cysteine and glutathione restore the reduction of rat hippocampal Na+, K+-ATPase activity induced by aspartame metabolites. Toxicology, 2007, Jul-31, Volume: 237, Issue:1-3 Topics: Animals; Animals, Suckling; Aspartame; Aspartic Acid; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Hippocampus; In Vitro Techniques; Male; Methanol; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sweetening Agents	2007
Validated chiral separation of M9, a Mannich ketone compound, by chiral ligand-exchange chromatography. Journal of separation science, 2007, Volume: 30, Issue:12 Topics: Antifungal Agents; Aspartame; Chemistry Techniques, Analytical; Chromatography; Copper; Ethanol; Hydrogen-Ion Concentration; Ketones; Ligands; Methanol; Models, Chemical; Reproducibility of Results; Temperature; Time Factors	2007
Commentary: further comments on Mycoplasma pulmonis and lymphoma in bioassays of rats. Veterinary pathology, 2011, Volume: 48, Issue:2 Topics: Animals; Animals, Laboratory; Aspartame; Biological Assay; Lung; Lymphoma; Methanol; Methyl Ethers; Mycoplasma Infections; Mycoplasma pulmonis; Rats; Rats, Sprague-Dawley; Rodent Diseases	2011
[Methanol poisoning in a 61-year old male with recently diagnosed diabetes--a case report]. Przeglad lekarski, 2011, Volume: 68, Issue:8 Topics: Animals; Aspartame; Beverages; Cattle; Diabetes Complications; Diabetes Mellitus; Drug Overdose; Fruit; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Male; Methanol; Middle Aged; Milk	2011
Effect of chronic exposure to aspartame on oxidative stress in the brain of albino rats. Journal of biosciences, 2012, Volume: 37, Issue:4 Topics: Animals; Aspartame; Brain; Free Radicals; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Male; Methanol; Methotrexate; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase	2012
A Rapid Dialysis Method for Analysis of Artificial Sweeteners in Foods (2nd Report). Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2017, Volume: 58, Issue:3 Topics: Aspartame; Calcium Carbonate; Chromatography, High Pressure Liquid; Citrates; Dialysis; Dialysis Solutions; Drug Combinations; Food Analysis; Hot Temperature; Hydrochloric Acid; Magnesium Oxide; Methanol; Phenylurea Compounds; Saccharin; Sodium Chloride; Sweetening Agents; Thiazines; Time Factors; Water	2017
Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR-CaMKII-ERK/CREB signalling on consumption of aspartame in rat model. Journal of food and drug analysis, 2018, Volume: 26, Issue:2 Topics: Animals; Apoptosis; Aspartame; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Female; Male; Memory; Methanol; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sweetening Agents	2018
A novel route for aspartame production by combining enzymatic and chemical reactions for industrial use. Bioscience, biotechnology, and biochemistry, 2021, Feb-18, Volume: 85, Issue:2 Topics: Acyltransferases; Aspartame; Chemistry Techniques, Synthetic; Industry; Methanol; Water	2021
The effects of aspartame on the HTR8/SVneo extravillous trophoblast cell line. Reproductive biology, 2022, Volume: 22, Issue:3 Topics: Aspartame; Aspartic Acid; Cell Line; Cell Movement; Female; Glucose; Humans; Methanol; Phenylalanine; Placenta; Pregnancy; Trophoblasts	2022