asparagine has been researched along with lysine in 385 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 130 (33.77) | 18.7374 |
| 1990's | 63 (16.36) | 18.2507 |
| 2000's | 136 (35.32) | 29.6817 |
| 2010's | 46 (11.95) | 24.3611 |
| 2020's | 10 (2.60) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Bonaventura, C; Bonaventura, J; Ferruzzi, G; Fox, J; McCurdy, PR; Moo-Penn, WF; Sullivan, B | 1 |
| Charache, S; Fox, J; Hathaway, P; Jessop, M; Kazazian, H; McCurdy, P; van Beneden, R; Winslow, R | 1 |
| Conti, SF; LaMarre, AG; Straley, SC | 1 |
| North, ML; Rosa, J; Thillet, J | 1 |
| Charache, S; Winslow, RM | 1 |
| Amegnizin, KP; Labie, D; Lapoumeroulie, C; Pagnier, J; Wajcman, H | 1 |
| Behnken, LJ; Kleihauer, E; Kohne, E; Leupold, D; Martin, H; Rogge, H | 1 |
| Amegnizin, KP; Belkhodja, O; Kernemp, R; Labie, D; Wajcman, H | 1 |
| Andrian, S; Das, DK; Moo-Penn, WF; Schneider, RG | 1 |
| Kleyn, JG | 1 |
| Bradley, TB; Budge, LJ; Graham, JL | 1 |
| Asano, M; Kudoh, H; Matsuoka, M; Miyaji, T; Ohba, Y; Satoh, T; Yamamoto, K | 1 |
| Carpenter, KJ; Hurrell, RF | 1 |
| Mauk, MR; Putz, GR; Taketa, F | 1 |
| Caskey, CT; Wasmuth, JJ | 1 |
| Black, JA; Harkins, RN; Stenzel, P | 1 |
| Chellemi, F | 1 |
| Welch, SG | 1 |
| Elbaum, D; Harrington, J; Nagel, RL; Roth, EF | 1 |
| Crespeau, H; Ferri, G; Galliano, M; Minchiotti, L; Porta, F; Rochu, D; Stoppini, M | 1 |
| Dauth, J; Nkhumeleni, FS; Pitout, MJ; Raubenheimer, EJ; Smith, PD; van Heerden, WF | 1 |
| Costa, FF; Sonati, MF; Zago, MA | 1 |
| Kawakami, K; Mikuni, O; Nakamura, Y | 1 |
| Blanquet, S; Boulanger, Y; Ebel, JP; Fasiolo, F; Hountondji, C; Sanni, A | 1 |
| Buivids, IA; Ellen, RP; Rosenberg, M | 1 |
| Bartel, D; Kietz, D; Lepke, S; Passow, H | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Accili, D; Kadowaki, H; Kadowaki, T; Taylor, SI | 1 |
| Gonzalez Redondo, JM; Huisman, TH; Kutlar, A; Kutlar, F; Webber, BB; Wilson, JB | 1 |
| Buechler, JA; Taylor, SS | 1 |
| Matthews, BW; Nicholson, H; Söderlind, E; Tronrud, DE | 1 |
| Johnson, MH; Jue, DL; Lonser, R; Moo-Penn, WF | 1 |
| Cantatore, P; Gadaleta, MN; Rainaldi, G; Roberti, M; Saccone, C | 1 |
| Aoki, N; Matsuda, M; Moroi, M; Okuma, M; Terukina, S; Yoshida, N | 1 |
| Hirakawa, M; Imamura, T; Kagimoto, M; Kawaguchi, T; Naito, Y; Naritomi, Y; Yokota, E | 1 |
| Burley, SK; Petsko, GA | 1 |
| Parker, J; Precup, J | 1 |
| Klibanov, AM; Tomazic, SJ | 1 |
| Broquist, HP | 1 |
| Cigén, R | 1 |
| Arous, N; Bardakjian, J; Blouquit, Y; Bohn, B; Galacteros, F; Leclerc, L; Oules, O; Poyart, C; Rafaillat, D; Rosa, J | 1 |
| Miyazawa, Y; Sekine, T; Yamaguchi, M | 1 |
| Dhar, MM; Mathur, KB; Naithani, VK | 1 |
| Haguenau, F; Michelson-Fiske, S; Rabotti, GF | 1 |
| Arnone, A; Perutz, MF | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Pogorelova, TN | 1 |
| Cotton, RG; Crawford, IP | 1 |
| Peterkofsky, A; Powers, DM | 1 |
| Camerer, W; Galanos, C; Rietschel, ET; Rietschel, M | 1 |
| Funatsu, G; Nierhaus, K; Wittmann, HG | 1 |
| Halpern, YS | 1 |
| Ali, A; Faesel, JH; Sarantakis, D; Stevenson, D; Weinstein, B | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Belkhodja, O; Elion, J; Labie, D; Wajcman, H | 1 |
| Karasawa, Y; Shibata, F; Tasaki, I; Yokota, HO | 1 |
| Lesk, AM | 1 |
| Bradenberger, H; Hediger, H; Schmid, K; Stevens, L | 1 |
| Beintema, JJ; Scheffer, AJ; Zwiers, H | 1 |
| Murthy, MR; Roux, H | 1 |
| Carlsson, FH | 1 |
| de Jong, WW; Went, LN | 1 |
| Ajmar, F; Arese, P; Gallo, E; Mazza, U; Pich, PG; Ricco, G; Rossi, G | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Salas, M; Stanley, WM; Wahba, AJ | 1 |
| Koehn, PV; Perlmann, GE | 1 |
| Berger, H; Yanofsky, C | 1 |
| Spiro, RG | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Hardman, JK; Myers, JS | 1 |
| Morihara, K; Tsuzuki, H | 1 |
| Adams, HR; Efremov, GD; Huisman, TH; Kitchens, JL; Smith, LL; Wilson, JB; Wrightstone, RN | 1 |
| Hong, B; Solie, TN; Tu, AT | 1 |
| Fujita, S | 1 |
| Gross, W; Ring, K | 1 |
| Anthony, C; Drabble, WT; Robinson, JH | 1 |
| Svábová-Stronová, M | 1 |
| Schwartz, JH | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Hersh, EM; Ohno, R | 1 |
| Greer, J | 1 |
| Graeber, W | 1 |
| Ochoa, S; Salas, M; Smith, MA; Stanley, WM; Wahba, AJ | 2 |
| Jones, OW; Nirenberg, MW | 1 |
| Barclay, GP; Charlesworth, D; Lehmann, H | 1 |
| Meyer, ME | 2 |
| Bjarnason, J; Carpenter, KJ | 1 |
| Charlesworth, D; Lehmann, H; Lorkin, PA; Vella, F | 1 |
| Lichtenstein, N; Lustig, N; Spiegelstein-Klarfeld, H | 1 |
| Wilke, J | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Boulton, FE; Huntsman, RG; Lehmann, H; Lorkin, PA; Romero Herrera, AE | 1 |
| Allen, LM; Vanecek, J; Wolfe, RG | 1 |
| Anfinsen, CB; Chaiken, IM | 1 |
| Waidyasekera, PL | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Thiry, L | 1 |
| Beale, D; Lehmann, H; Van Ros, G | 1 |
| Bodnaryk, RP; Levenbook, L | 1 |
| Schneider, G | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Jefferson, LS; Korner, A | 1 |
| Blackwell, RQ; Wang, CC; Yang, HJ | 1 |
| Bradley, TB; Jacobs, AS; Ramot, B; Ranney, HM | 1 |
| Khodos, KhG; Kozarenko, TD; Okladnikov, VI | 1 |
| Munier, RL; Sarrazin, G | 1 |
| Fleischmann, L; Santamaria, L | 1 |
| Andreeva, LA | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Dimaria, P; Farooqui, J; Kim, CS; Kim, S; Kueppers, F; Paik, WK | 1 |
| Hidaka, K; Iuchi, I; Mizuta, W; Shimasaki, S | 1 |
| Hodgson, B; Rao, AS | 1 |
| Friesen, JD; Parker, J | 1 |
| Borgia, PT; Johnston, TC; Parker, J | 1 |
| Gandar, R; Hassan, W; North, ML; Ritter, J; Rosa, J; Schwartz, M; Taubert, C; Thillet, J | 1 |
| Wold, F | 1 |
| Hattori, Y; Matsui, Y; Miwa, S; Miyaji, T; Miyata, H; Nakatsuji, T; Ohba, Y; Shinohara, T | 1 |
| Headlee, ME; Henson, J; Huisman, TH; Lam, H; Wilson, JB; Yi-Tao, Z | 1 |
| Hopfer, SM; Kevorkian, CB; McCully, KS; Reid, MC; Sunderman, FW | 1 |
| Dlouhy, SR; Hodes, ME; Marks, HG; Naidu, S; Pratt, VM | 1 |
| Fukuda, K; Kato, S; Mori, K; Terasako, K | 1 |
| Garcia-Horsman, JA; Gennis, RB; Puustinen, A; Wikström, M | 1 |
| Akhtaruzzaman, M; Kimura, Y; Takagi, S | 1 |
| Offer, G; Sessions, R | 1 |
| Bartolone, L; Benvenga, S; Filetti, S; Pontecorvi, A; Regalbuto, C; Trimarchi, F | 1 |
| Kodama, H; Sugahara, K; Zhang, J | 1 |
| Chida, Y; Kamio, K; Kikawa, E; Nakazawa, M; Shiono, T; Tamai, M | 1 |
| Häberlein, I | 1 |
| Balasubramanian, S; Boxer, SG; Lambright, DG; Lambry, JC; Martin, JL; Petrich, JW | 1 |
| Aswad, DW; Henzel, WJ; Potter, SM | 1 |
| Castellino, FJ; Davidson, DJ | 1 |
| Furlan, M; Heinemann, G; Jungo, M; Lämmle, B; Reber, P; Steinmann, C; Wermuth, B | 1 |
| Sanna, MG; Simon, MI | 1 |
| Hamasaki, N; Kang, D; Mori, A; Okubo, K | 1 |
| Gastmann, U; Häussinger, D; Keul, J; Lehmann, M; Mann, H; Steinacker, JM; Vetter, D | 1 |
| Brahic, M; Jarousse, N; Martinat, C; McAllister, A; Syan, S | 1 |
| Edwards, RH; Kaback, HR; Merickel, A | 1 |
| Eldin, S; Knight, KL; Logan, KM; Skiba, MC | 1 |
| Himanen, JP; Manning, JM; Popowicz, AM | 1 |
| Denis, PE; Feinstein, SC; Goode, BL; Miller, HP; Panda, D; Radeke, MJ; Wilson, L | 1 |
| Balis, C; Kyriacou, A; Typas, MA | 1 |
| Ades, SE; Chambers, KA; Pabo, CO; Rould, MA; Sauer, RT; Tucker-Kellogg, L | 1 |
| Andersen, R; Cheskin, LJ; Chung, WK; Elahi, D; Leibel, RL; Muller, D; Parikh, VV; Shuldiner, AR; Silver, K; Walston, J; Yao, F | 1 |
| Clark, BF; Knudsen, CR; Nautrup Pedersen, G; Rattenborg, T | 1 |
| Hata, S; Izui, K; Ueno, Y | 1 |
| Wang, GK; Wang, SY | 1 |
| Endo, K; Esaki, N; Fuchikami, Y; Kishimoto, K; Liu, L; Manning, JM; Soda, K; Yoshimura, T | 1 |
| Aldrich, HC; Ferry, JG; Maupin-Furlow, JA | 1 |
| Grubmeyer, C; Xu, Y | 1 |
| Galliano, M; Kragh-Hansen, U; Li, B; Minchiotti, L; Savva, D; Tárnoky, AL | 1 |
| Ash, DE; Dismukes, GC; Khangulov, SV; Sossong, TM | 1 |
| Quirk, DJ; Raines, RT; Schultz, LW | 1 |
| Finazzi, G; Joliot, P; Wollman, FA; Zito, F | 1 |
| Giordano, H; Liang, L; Peterson, MG; Sivaraja, M; Spector, FC | 1 |
| Brennan, SO; George, PM; Loreth, RM | 1 |
| Hedstrom, L; Lin, TY; Liu, X; Pasternak, A | 1 |
| Christendat, D; Saridakis, VC; Turnbull, JL | 1 |
| Munagala, NR; Wang, CC | 1 |
| Brooker, RJ; Johnson, JL | 1 |
| Tomita, K; Ueda, T; Watanabe, K | 1 |
| Ezquieta Zubicaray, B; González Gancedo, P; Gracia Bouthelier, R; Iguacel, AO; Jariego Fente, CM; Varela Junquera, JM | 1 |
| Fucharoen, S; Itchayanan, D; Srisomsap, C; Svasti, J; Winichagoon, P | 1 |
| Alvarez, M; Depiereux, E; Maes, D; Mainfroid, V; Martial, JA; Rentier-Delrue, F; Wouters, J; Wyns, L | 1 |
| Gilman, AG; Mukhopadhyay, S; Posner, BA; Ross, EM; Tesmer, JJ | 1 |
| Abbenante, G; Alewood, D; Alewood, PF; Begun, J; Bergman, DA; Brinkworth, RI; Fairlie, DP; March, DR; Martin, JL; Reid, RC; Schindeler, A; Wickramasinghe, WA | 1 |
| Karam, J; Konigsberg, WH; Lin, T; Yang, G | 1 |
| Ho, C; Ho, NT; Shen, TJ; Tsai, CH | 1 |
| ffrench-Constant, RH; Jackson, MB; Rocheleau, TA; Wang, CT; Zhang, HG | 1 |
| Acharya, AS; Friedman, JM; Gottfried, DS; Malavalli, A; Manjula, BN | 1 |
| Hendrich, MP; Ho, C; Ho, NT; Jeong, ST | 1 |
| Suzuki, T; Varshavsky, A | 1 |
| Gang Yuan, R; Jenuth, JP; Litster, SA; Maynes, JT; Phipps, BM; Snyder, FF; Yam, W | 1 |
| Ibarra-Molero, B; Loladze, VV; Makhatadze, GI; Sanchez-Ruiz, JM | 1 |
| Balboni, G; Capasso, S; Di Cerbo, P | 1 |
| Beavil, AJ; Davison, E; Kirby, I; Kovesdi, I; Roelvink, PW; Santis, G; Soh, CP; Sutton, BJ; Wickham, TJ | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| DiMarco, M; Gagnon, L; Kirby, R; Penney, CL; Zacharie, B | 1 |
| Célérier, J; Corvol, P; Iturrioz, X; Llorens-Cortès, C; Vazeux, G | 1 |
| Abe, Y; Kim, JH; Kohda, D; Saito, K; Sato, C; Yokoyama, S | 1 |
| Fujita, K; Katsuyama, T; Okumura, N; Ota, H; Terasawa, F; Tozuka, M | 1 |
| Hinchliffe, SJ; Morgan, BP | 1 |
| Arima, K; Hasegawa, M; Iwatsubo, T; Kawai, M; Kowalska, A; Mukoyama, M; Sunohara, N; Tabira, T; Takahashi, K; Watanabe, R | 1 |
| Elleder, M; Francová, H; Hrabincová, E; Kozák, L; Pesková, K; Stastná, S | 1 |
| Brown, KM; Forbes, SL; Liggett, SB; Small, KM | 1 |
| Brennan, RG; Goodman, RH; Schumacher, MA | 1 |
| Duda, RL; Hendrix, RW; Johnson, JE; Liljas, L; Tsuruta, H; Wikoff, WR | 1 |
| Allocati, N; Casalone, E; Di Ilio, C; Masulli, M; Parker, MW; Polekhina, G; Rossjohn, J | 1 |
| Kraynov, VS; Liu, J; Showalter, AK; Tsai, MD; Zhong, X | 1 |
| Bramley, AJ; Kerr, DE; Lax, AJ; Moore, K; Plaut, K; Wall, RJ; Wells, KD; Williamson, CM | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Miyahara, I; Mizuguchi, H; Okada, K | 1 |
| Hwang, JJ; Stupp, SI | 1 |
| Babolat, M; Deville-Bonne, D; Janin, J; Schneider, B; Véron, M; Xu, YW | 1 |
| Eriguchi, Y; Haruta, S; Sawai, T; Yamamoto, ET | 1 |
| Bagwell, C; Banik, U; Dunn, MF; Hur, O; Miles, EW; Weber-Ban, E; Yang, LH | 1 |
| Matsuno, H; Niikura, K; Okahata, Y | 1 |
| Funahashi, J; Takano, K; Yutani, K | 1 |
| Aoki, K; Arakawa, T; Boone, T; Cheetham, J; Elliott, S; Narhi, LO; Wen, J | 1 |
| De Angelis, S; Degani, V; Leone, D; Murtas, R; Rabino-Massa, E | 1 |
| Cherepanov, DA; Mulkidjanian, AY | 1 |
| Argos, P; Gianese, G; Pascarella, S | 1 |
| Jørgensen, JR; Pedersen, PA | 1 |
| Aeschliman, SM; Ballou, DP; Massey, V; Ortiz-Maldonado, M | 1 |
| Angulo, Y; Lomonte, B; Núñez, CE | 1 |
| Barile, M; Wang, GK; Wang, SY | 1 |
| Bennett, GS; Chakraborti, T; Fu, Z; Morse, S; Shaw, G | 1 |
| Casey, ES; Conlon, FL; Fairclough, L; Price, BM; Smith, JC | 1 |
| Conesa-Zamora, P; Corbalán-García, S; Gómez-Fernández, JC; Lopez-Andreo, MJ | 1 |
| Bambino, T; Chauvin, S; Krasel, C; Lohse, MJ; Nissenson, RA; Vilardaga, JP | 1 |
| Chong, JM; Rubin, JS; Speicher, DW; Uren, A | 1 |
| Fernandes, AS; Gerchman, SE; Gilboa, R; Golan, G; Grollman, AP; Kycia, JH; Matz, E; Shoham, G; Zharkov, DO | 1 |
| Fujioka, M; Gomi, T; Huang, Y; Komoto, J; Ogawa, H; Takata, Y; Takusagawa, F; Yamada, T | 1 |
| Owen, D; Perutz, MF; Pope, BJ; Scherzinger, E; Wanker, EE | 1 |
| Cameron, I; Gaffney, D; Hoffs, MS; Kane, JP; Kulkarni, MV; O'Reilly, DS; Packard, CJ; Pullinger, CR; Schumaker, VN; Vass, JK; Watts, GF | 1 |
| Baker, M; Brefel-Courbon, C; Delisle, MB; Ferreira, JJ; Ghetti, B; Hutton, M; Murrell, JR; Rascol, O; Tsuboi, Y; Uitti, RJ; Wszolek, ZK | 1 |
| Flanigan, TP; Kurpewski, J; Melanson, SM; Skolnik, PR; Tashima, KT | 1 |
| Koizumi, Ki; Koseki, H; Kuriyama, T; Sakai, H; Shimizu, T; Shirasawa, T; Suzuki, Y; Tamaki, M; Tsuchida, E | 1 |
| Chalisova, NI; Haase, G; Pennijainen, VA | 1 |
| Enyedi, A; Filoteo, AG; Padányi, R; Pászty, K; Penheiter, AR; Penniston, JT; Verma, AK | 1 |
| Klimacek, M; Nidetzky, B | 1 |
| Ayukarn, K; Changtrakun, Y; Fucharoen, G; Fucharoen, S; Sanchaisuriya, K; Siriratmanawong, N | 1 |
| Abe, F; Miura, K; Saito, K; Toriyama, K | 1 |
| Arnberg, N; Edlund, K; Kidd, AH; Nilsson, J; Pring-Akerblom, P; Wadell, G | 1 |
| Acharya, A; Gal, J; Moll, JR; Ruvinov, SB; Vinson, C | 1 |
| Bies, C; Blatch, GL; Hornby, JA; Odunuga, OO; Pugh, DJ; Zimmermann, R | 1 |
| Cowman, AF; Foth, BJ; Fraunholz, M; McFadden, GI; Ralph, SA; Roos, DS; Struck, NS; Tonkin, CJ | 1 |
| Galili, G; Zhu, X | 2 |
| Aldred, S; Fitzgerald, M; Moore, KM; Waring, RH | 1 |
| De Pont, JJ; Koenderink, JB; Swarts, HG; Willems, PH | 1 |
| Harano, K; Harano, T; Hong, YF; Kuroda, A; Suetsugu, Y; Than, AM | 1 |
| Andreux, F; Barois, A; Bauché, S; Eymard, B; Fardeau, M; Fournier, E; Gaudon, K; Hainque, B; Hantaï, D; Ioos, C; Koenig, J; Leroy, JP; Mayer, M; Mokhtari, M; Prioleau, C; Richard, P; Routon, MC; Yasaki, E | 1 |
| Daiho, T; Danko, S; Iizuka, H; Suzuki, H; Wang, G; Yamasaki, K | 1 |
| Prabhakar, R; Siegbahn, PE | 1 |
| Biddison, WE; Damirjian, M; Gagnon, SJ; Turner, R; Wang, Z | 1 |
| Drac, H; Hausmanowa-Petrusewicz, I; Jedrzejowska, H; Kochański, A | 1 |
| Cole, SP; Deeley, RG; Gu, HM; Haimeur, A; Situ, D; Zhang, DW | 1 |
| Barbeau, P; Harshfield, G; Kang, HS; Pollock, DM; Pollock, JS; Snieder, H; Treiber, FA | 1 |
| Robertson, AD; Sundd, M | 1 |
| CAMERON, HS; MEYER, ME | 1 |
| WOLLENWEBER, P | 1 |
| DECONNINCK, G; VOETS, JP | 1 |
| BRAUN, L | 1 |
| CHRISTENSEN, HN | 1 |
| ENSIGN, JC; WOLFE, RS | 1 |
| Breuer, LH; Loosli, JK; Pond, WG; Warner, RG | 1 |
| DELALLOSA, P; JUTISZ, M; TERTRIN, C | 1 |
| SASAKI, T; SHIMURA, K; SUGAWARA, K | 1 |
| HACHISUKA, Y | 1 |
| KIM, S; PAIK, WK | 1 |
| GERIFFIN, G; KESNER, L; MUNTWYLER, E | 1 |
| HENRY, L; HOBBS, H; NIEDERPRUEM, DJ | 1 |
| BERNFIELD, MR; BRIMACOMBE, RL; LEDER, P; NIRENBERG, MW; ROTTMAN, FM; TRUPIN, JS | 1 |
| GAEVSKAYA, MS; GERSHTEIN, LM; NOSOVA, EA; PORTUGALOV, VV | 1 |
| Chalisova, NI; Penniiaĭnen, VA | 1 |
| Engel, AG; Ohno, K | 1 |
| de Jong, AS; Glaudemans, DH; Melchers, WJ; van Kuppeveld, FJ; Willems, PH | 1 |
| Anderson, ME; Bhansali, VS; Cundari, TR; Dinescu, A; Luo, JL | 1 |
| Brunori, M; D'Itri, E; Forte, E; Giuffrè, A; Ludwig, B; Richter, OM; Sarti, P; Scandurra, FM | 1 |
| Beck, A; Brandenburg, J; Burster, T; Driessen, C; Falk, K; Kalbacher, H; Lautwein, A; Lehmann, R; Marin-Esteban, V; Melms, A; Reich, M; Rötzschke, O; Schwarz, G; Stevanovic, S; Tolosa, E; Wiendl, H | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Bramlett, MR; Feng, J; Kim, EJ; Lindahl, PA | 1 |
| Cheng, N; Conway, JF; Duda, RL; Firek, BA; Gan, L; Hendrix, RW; Johnson, JE; Steven, AC | 1 |
| Kamide, K; Kawano, Y; Miyata, T; Takiuchi, S; Tanaka, C | 1 |
| Garneau, P; Kumar, R; Nguyen, N; Pelletier, J; William Lown, J | 1 |
| Alleva, DG; Nickolls, SA; Ott, TR; Pahuja, A; Struthers, RS | 1 |
| Abicht, A; Baumeister, SK; Beeson, D; Burke, G; Cossins, J; Eymard, B; Hantaï, D; Lochmüller, H; Müller, JS; Richard, P; Stucka, R | 1 |
| Cheng, X; Collins, RE; Horton, JR; Sawada, K; Yang, Z; Zhang, X | 1 |
| Segaloff, DL; Tao, YX | 1 |
| Arima, K; Baba, Y; Ghetti, B; Hutton, ML; Kobayashi, T; Rascol, O; Tsuboi, Y; Woodruff, BK; Wszolek, ZK; Yasuda, M | 1 |
| Akinsete, O; Cartwright, C; Henry, K; Hirigoyen, D; Kantor, R; Schut, R | 1 |
| Boado, RJ; Li, JY; Pardridge, WM; Wise, P | 1 |
| Guan, Z; McClerren, AL; Raetz, CR; Rudolph, J; Zhou, P | 1 |
| Antipina, VV; Makarova, ER; Minushkina, LO; Nosikov, VV; Petrova, IR; Romanova, TA; Sidorenko, BA; Zateĭshikov, DA | 1 |
| Christendat, D; Collart, F; Joachimiak, A; Korolev, S; Koroleva, O; Singh, S; Zarembinski, T | 1 |
| Dalal, S; Starcevic, D; Sweasy, J | 1 |
| Brenna, JT; Sacks, GL | 1 |
| Ballou, DP; Brinker, DR; Casas, KR; Galloway, LJ; Scannell, SA; Trimmer, EE | 1 |
| Antonini, G; Burmeister, C; Caccuri, AM; De Maria, F; Federici, G; Giansanti, F; Liebau, E; Lo Bello, M; Perbandt, M; Ricci, G; Stella, L; Turella, P | 1 |
| Beghini, A; Bellini, M; Cairoli, R; Colapietro, P; Larizza, L; Magnani, I; Morra, E | 1 |
| Fu, Y; Katsuya, T; Masuo, K; Ogihara, T; Rakugi, H; Tuck, ML | 1 |
| Freindorf, M; Furlani, TR; Kong, J; Shao, Y | 1 |
| Drown, PM; MacDonald, G; Schwartz, CM | 1 |
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| Baker, EN; Gaspar, AH; Kang, HJ; Paterson, NG; Ton-That, H | 1 |
| Chang, YH; Chiu, CC; Chuang, LY; Hwang, CC; Wang, CZ | 1 |
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| Caplan, S; Giridharan, SS; Jovic, M; Kieken, F; Naslavsky, N; Sharma, M; Sorgen, PL | 1 |
| Chimirri, A; Crespan, E; Logoteta, P; Maga, G; Monforte, AM; Samuele, A; Vitellaro, S | 1 |
| Ginty, DD; Kolodkin, AL; Leahy, DJ; Merte, J; Sarsfield, S; Vander Kooi, CW; Wang, Q | 1 |
| Hoang, PV; Ito, M; Kawaoka, Y; Kiso, M; Le, QM; Muramoto, Y; Ozawa, M; Sakai-Tagawa, Y; Takano, R; Vuong, CD | 1 |
| Bobek-Billewicz, B; Cybulski, C; Lubiński, J; Majchrzak, H; Majchrzak, K | 1 |
| Bau, AE; de Zwart-Storm, EA; Foelster-Holst, R; Frank, J; Graziadio, C; Kamps, MA; Martin, PE; Paskulin, GA; Rosa, RF; van Geel, M; van Steensel, MA; Zen, PR | 1 |
| Hattori, N; Li, Y; Motoi, Y; Nakanishi, A; Ogaki, K; Shimizu, N; Takanashi, M; Tomiyama, H; Yokoyama, K | 1 |
| Boeve, BF; Dickson, DW; Dugger, BN; Fredrickson, P; Kaplan, J; Lin, SC; Spector, AR; Strongosky, A; Uitti, RJ; Wszolek, ZK | 1 |
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| Baker, EN; Kwon, H; Squire, CJ; Young, PG | 1 |
| García-García, A; Loera-Arias, MJ; Montes-de-Oca-Luna, R; Rodríguez-Rocha, H; Saucedo-Cárdenas, O; Villa-Cedillo, SA; Zavala-Flores, LM | 1 |
| Miyauchi, K; Nagao, A; Ohara, M; Suzuki, T; Watanabe, K; Yamagishi, A; Yokobori, SI | 1 |
| Danmaliki, GI; Hwang, PM; Liu, PB | 1 |
| Cronmiller, LE; Elibol, M; Ozturk, TK; Tepe, M; Turner, EG; Yazgan, I | 1 |
| Aviyente, V; Bali, SK; Catak, S; Dikmenli, AK; Marion, A; Ugur, I | 1 |
| Balgera, R; Comi, GP; Lucchiari, S; Mantero, V; Rigamonti, A; Salmaggi, A | 1 |
| Chen, S; Chen, Z; Cui, F; Huang, X; Li, Y; Ling, L; Ren, Y; Sun, B; Yang, F | 1 |
| Fatima, S; Hafeez, A; Ijaz, AIA; Memon, AA; Waseem, M | 1 |
| Gomez, GVB; Lima, CSP; Lourenço, GJ; Moraes, AM; Oliveira, C; Rinck-Junior, JA; Torricelli, C | 1 |
| Liu, H; Nowak, C; Patel, R | 1 |
| Antosik, J; Bednarek, E; Bierczyńska-Krzysik, A; Bocian, W; Borowicz, P; Kozerski, L; Sitkowski, J; Stadnik, D; Zielińska, J | 1 |
| Lin, PY; Yang, KL | 1 |
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| Chen, J; He, Z; Jiao, Y; Li, Y; Liu, G; Qin, F; Quan, W; Wang, Z; Xue, C; Zeng, M | 1 |
| Li, W; Peng, Y; Yang, Y; Zhang, N; Zheng, J; Zhou, S | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Ascher, DB; Boer, JC; Holien, JK; Nguyen, TB; Pan, Q; Plebanski, M | 1 |
| Bae, E; Jo, HA; Kim, DJ; Kim, DK; Kim, YS; Lee, S; Seo, JH; Yang, SH; Yu, MY | 1 |
| Ho, CT; Huang, Q; Xiao, Q | 1 |
| Brown, K; Huff-Lonergan, EJ; Johnson, LG; Lonergan, SM; N Nair, M; Prenni, JE; Zhai, C | 1 |
| Li, J; Sun, X; Yan, S | 1 |
| Bertinato, J; Hendry, A; Kenney, L; Xiao, CW | 1 |
9 review(s) available for asparagine and lysine
| Article | Year |
|---|---|
Amino acid composition of dentine in permanent human teeth.
Topics: Amino Acids; Asparagine; Aspartic Acid; Dentin; Glutamates; Glutamic Acid; Humans; Hydroxylysine; Lysine | 1992 |
The indolizidine alkaloids, slaframine and swainsonine: contaminants in animal forages.
Topics: Alkaloids; alpha-Mannosidase; Animal Diseases; Animal Feed; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Fabaceae; Female; Food Contamination; Glycoproteins; Goats; Horses; Humans; Lysine; Male; Mannosidases; Mycotoxins; Nervous System Diseases; Plants, Medicinal; Rats; Sheep; Sialorrhea; Substance-Related Disorders; Swainsonine; Swine | 1985 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Glycoproteins.
Topics: Amino Acids; Animals; Asparagine; Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Chemical Phenomena; Chemistry; Enzymes; Glycoproteins; Hydroxyproline; Kinetics; Lysine; Polysaccharides; Serine; Threonine; Transferases | 1970 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Snake venom Lys49 myotoxins: From phospholipases A(2) to non-enzymatic membrane disruptors.
Topics: Animals; Asparagine; Cell Membrane; Crotalid Venoms; Dimerization; Evolution, Molecular; Gene Expression Regulation, Enzymologic; Lysine; Muscle, Skeletal; Necrosis; Neurotoxins; Phospholipases A2; Structure-Activity Relationship; Viperidae | 2012 |
Self-generated covalent cross-links in the cell-surface adhesins of Gram-positive bacteria.
Topics: Adhesins, Bacterial; Asparagine; Aspartic Acid; Bacterial Adhesion; Fimbriae Proteins; Glutamine; Gram-Positive Bacteria; Lysine; Models, Molecular; Protein Conformation; Protein Folding; Protein Interaction Domains and Motifs; Protein Stability; Threonine | 2015 |
Modifications of recombinant monoclonal antibodies in vivo.
Topics: Animals; Antibodies, Monoclonal; Asparagine; Cysteine; Disulfides; Glutamine; Glycosylation; Humans; Lysine; Pharmaceutical Preparations; Protein Processing, Post-Translational; Recombinant Proteins; Succinimides; Time Factors | 2019 |
2 trial(s) available for asparagine and lysine
| Article | Year |
|---|---|
Influence of Lys656Asn polymorphism of leptin receptor gene on leptin response secondary to two hypocaloric diets: a randomized clinical trial.
Topics: Asparagine; Body Mass Index; Diet, Carbohydrate-Restricted; Diet, Fat-Restricted; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Female; Genotype; Humans; Leptin; Lysine; Male; Middle Aged; Obesity; Polymorphism, Genetic; Prospective Studies; Receptors, Leptin; Weight Loss | 2008 |
Effect of the Tottori familial disease mutation (D7N) on the monomers and dimers of Aβ40 and Aβ42.
Topics: Alzheimer Disease; Amination; Amyloid beta-Peptides; Asparagine; Aspartic Acid; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Dynamics Simulation; Multiprotein Complexes; Mutation; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary; Static Electricity; Substrate Specificity; Up-Regulation | 2013 |
374 other study(ies) available for asparagine and lysine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Hemoglobin providence. Functional consequences of two alterations of the 2,3-diphosphoglycerate binding site at position beta 82.
Topics: Adult; Asparagine; Aspartic Acid; Binding Sites; Carbon Monoxide; Diphosphoglyceric Acids; Female; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Conformation; Osmolar Concentration; Oxygen; Phytic Acid; Protein Conformation; Sodium Chloride | 1976 |
Postsynthetic deamidation of hemoglobin Providence (beta 82 Lys replaced by Asn, Asp) and its effect on oxygen transport.
Topics: Adolescent; Adult; Asparagine; Aspartic Acid; Child, Preschool; Diphosphoglyceric Acids; Erythrocytes; Female; Glycine; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Infant; Leucine; Lysine; Male; Oxygen; Peptide Fragments; Protein Binding | 1977 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Functional properties of Hb Stanleyville II alpha 78 (EF 7) asparagine replaced by lysine. Effect of sodium chloride.
Topics: Asparagine; Erythrocytes; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Lysine; Osmolar Concentration; Oxygen; Oxyhemoglobins; Sodium Chloride | 1979 |
Hemoglobin Richmond. Subunit dissociation and oxygen equilibrium properties.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Carbon Monoxide; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kansas; Kinetics; Lysine; Macromolecular Substances; Oxygen; Threonine; Virginia | 1975 |
Hb J Lome beta 59 (E3) Lys is replaced by Asn associated with HPFH in a Togolese family.
Topics: Asparagine; Child; Female; Fetal Hemoglobin; Genetic Carrier Screening; Hemoglobin J; Hemoglobins, Abnormal; Humans; Lysine; Pedigree; Togo | 1979 |
Hemoglobin Presbyterian [beta 108 (G10) Asn replaced by Lys] in a German family.
Topics: Adult; Asparagine; Electrophoresis, Cellulose Acetate; Female; Germany; Hemoglobins, Abnormal; Humans; Lysine; Male | 1979 |
Hemoglobin J Lome beta 59 (E3) Lys leads to Asn. A new fast moving variant found in a Togolese.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Hemoglobins, Abnormal; Humans; Lysine; Peptide Fragments | 1977 |
Hemoglobin Detroit: beta95 (FG2) lysine leads to asparagine.
Topics: Adult; Amino Acid Sequence; Amino Acids; Asparagine; Diphosphoglyceric Acids; Female; Hemoglobin A; Hemoglobin J; Hemoglobins, Abnormal; Humans; Kinetics; Lysine; Oxygen; Peptide Fragments | 1978 |
The effect of aminopterin (4-amino folic acid) on growth and cell division of fermentative versus oxidative yeasts.
Topics: Aminopterin; Asparagine; Biotin; Cell Division; Fermentation; Lysine; Oxidation-Reduction; Species Specificity; Thymine; Yeasts | 1977 |
Hemoglobin Riyadh in a Mexican American family of Spanish ancestry.
Topics: Adolescent; Amino Acids; Asparagine; Electrophoresis, Cellulose Acetate; Female; Hemoglobins, Abnormal; Humans; Lysine; Peptide Fragments | 1977 |
Hemoglobin Karatsu: beta 120 (GH 3) lysine leads to asparagine, an example of HB Riyadh in Japan.
Topics: Aged; Amino Acids; Asparagine; Electrophoresis, Cellulose Acetate; Hemoglobins, Abnormal; Humans; Japan; Lysine; Male; Peptides; Spectrum Analysis | 1977 |
Nutritional significance of cross-link formation during food processing.
Topics: Amino Acids; Animals; Asparagine; Caseins; Chemical Phenomena; Chemistry; Chickens; Dietary Proteins; Digestion; Food Handling; Glucose; Hot Temperature; Lysine; Meat; Methionine; Nutritional Physiological Phenomena; Proteins; Rats | 1977 |
Turnover of amino-terminal acetylated and non-acetylated hemoglobins in vivo.
Topics: Acetates; Animals; Arginine; Asparagine; Blood Cell Count; Cats; Glycine; Hematocrit; Hemoglobins; Hemoglobins, Abnormal; Kinetics; Lysine; Phenotype; Reticulocytes; Serine; Time Factors | 1976 |
Selection of temperature-sensitive CHL asparagyl-tRNA synthetase mutants using the toxic lysine analog, S-2-aminoethyl-L-cysteine.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Cell Line; DNA; Genes; Lysine; Mutation; Protein Biosynthesis; Temperature | 1976 |
The terminal amino acids of protein sequences and protein maturation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Cell Nucleus; Codon; Glutamine; Lysine; Methionine; Peptide Chain Termination, Translational; Peptide Hydrolases; Phenylalanine; Protein Biosynthesis; Serine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Haemoglobin G Szuhu beta 80 asn leads to lys in an English family.
Topics: Amino Acid Sequence; Asparagine; England; Female; Hemoglobins, Abnormal; Humans; Lysine; Male; Peptide Fragments; Taiwan | 1975 |
Surface activity of hemoglobin S and other human hemoglobin variants.
Topics: Asparagine; Aspartic Acid; Glutamates; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Lysine; New York City; Osmolar Concentration; Oxygen; Pressure; Protein Conformation; Sodium Chloride; Surface Properties; Thermodynamics; Valine | 1976 |
Two alloalbumins with identical electrophoretic mobility are produced by differently charged amino acid substitutions.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Genetic Variation; Glutamates; Glutamic Acid; Humans; Isoelectric Focusing; Lysine; Molecular Sequence Data; Mutation; Serum Albumin | 1992 |
Hemoglobin Stanleyville II (alpha 78 Asn----Lys) is associated with a 3.7-kb alpha-globin gene deletion.
Topics: Asparagine; Chromosome Deletion; Chromosome Mapping; DNA; Female; Genetic Carrier Screening; Globins; Hemoglobins, Abnormal; Homozygote; Humans; Leukocytes; Lysine; Male; Polymorphism, Restriction Fragment Length | 1991 |
Sequence and functional analysis of mutations in the gene encoding peptide-chain-release factor 2 of Escherichia coli.
Topics: Amino Acid Sequence; Asparagine; Blotting, Southern; Codon; Escherichia coli; Lysine; Molecular Sequence Data; Mutation; Peptide Chain Termination, Translational; Peptide Termination Factors; Protein Biosynthesis; Suppression, Genetic | 1991 |
Interaction of the tRNA(Phe) acceptor end with the synthetase involves a sequence common to yeast and Escherichia coli phenylalanyl-tRNA synthetases.
Topics: Amino Acid Sequence; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Lysine; Macromolecular Substances; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Phenylalanine-tRNA Ligase; RNA, Transfer, Phe; Saccharomyces cerevisiae | 1991 |
Adhesion of Actinomyces viscosus to Porphyromonas (Bacteroides) gingivalis-coated hexadecane droplets.
Topics: Actinomyces; Alkanes; Arginine; Asparagine; Bacterial Adhesion; Bacteroides; Lysine; Microscopy, Electron; Phenylalanine; Serum Albumin, Bovine | 1991 |
pH-dependence of inhibition by H2DIDS of mouse erythroid band 3-mediated Cl- transport in Xenopus oocytes. The effect of oligonucleotide-directed replacement of Lys-558 by an Asn residue.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anion Exchange Protein 1, Erythrocyte; Asparagine; Chlorides; Erythrocyte Membrane; Hydrogen-Ion Concentration; Kinetics; Lysine; Mice; Mutagenesis, Site-Directed; Oligonucleotide Probes; Oocytes; Temperature; Xenopus | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Substitution of lysine for asparagine at position 15 in the alpha-subunit of the human insulin receptor. A mutation that impairs transport of receptors to the cell surface and decreases the affinity of insulin binding.
Topics: Animals; Asparagine; Base Sequence; Cell Line; Cell Membrane; Humans; Insulin; Kinetics; Lysine; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phosphorylation; Receptor, Insulin; Transfection | 1990 |
Hb F-Clarke or alpha 2G gamma 2(65)(E9)Lys----Asn.
Topics: Amino Acids; Asparagine; Chromatography, High Pressure Liquid; Fetal Hemoglobin; Hemoglobins, Abnormal; Hispanic or Latino; Humans; Infant, Newborn; Lysine; Male; Peptide Mapping | 1987 |
Dicyclohexylcarbodiimide cross-links two conserved residues, Asp-184 and Lys-72, at the active site of the catalytic subunit of cAMP-dependent protein kinase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Carbodiimides; Catalysis; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dicyclohexylcarbodiimide; Lysine; Models, Molecular; Peptide Fragments; Protein Kinase Inhibitors; Protein Kinases | 1989 |
Contributions of left-handed helical residues to the structure and stability of bacteriophage T4 lysozyme.
Topics: Amino Acid Sequence; Asparagine; Crystallography; Enzyme Stability; Glycine; Lysine; Molecular Sequence Data; Muramidase; Mutation; Protein Conformation; T-Phages; Thermodynamics; Viral Proteins | 1989 |
Hb Hinsdale [beta 139 (H17)Asn----Lys]: a variant in the central cavity showing reduced affinity for oxygen and 2,3-diphosphoglycerate.
Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Asparagine; Chromatography, High Pressure Liquid; Diphosphoglyceric Acids; Female; Genetic Variation; Hemoglobins, Abnormal; Humans; Kinetics; Lysine; Male; Molecular Sequence Data; Oxyhemoglobins; Peptide Fragments; Trypsin | 1989 |
The complete nucleotide sequence, gene organization, and genetic code of the mitochondrial genome of Paracentrotus lividus.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Biological Evolution; Chromosome Mapping; Codon; DNA, Mitochondrial; Electron Transport Complex IV; Genetic Code; Isoleucine; Lysine; Methionine; Molecular Sequence Data; Proteins; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Sea Urchins | 1989 |
Characterization of an apparently lower molecular weight gamma-chain variant in fibrinogen Kyoto I. The replacement of gamma-asparagine 308 by lysine which causes accelerated cleavage of fragment D1 by plasmin and the generation of a new plasmin cleavage
Topics: Amino Acid Sequence; Asparagine; Calcium; Chromatography, High Pressure Liquid; Cyanogen Bromide; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Genetic Variation; Humans; Lysine; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Serine Endopeptidases | 1988 |
Identification of abnormal hemoglobin (J Lome): beta 59 (E3) lysine----asparagine in a Japanese.
Topics: Asparagine; Diabetes Mellitus; Hemoglobin J; Hemoglobins, Abnormal; Humans; Liver Cirrhosis; Lysine; Male; Middle Aged | 1986 |
Amino-aromatic interactions in proteins.
Topics: Arginine; Asparagine; Crystallography; Glutamine; Histidine; Lysine; Proteins | 1986 |
Missense misreading of asparagine codons as a function of codon identity and context.
Topics: Asparagine; Bacteriophages; Base Sequence; Capsid; Capsid Proteins; Cloning, Molecular; Codon; DNA, Recombinant; Escherichia coli; Lysine; Mutation; Plasmids; Protein Biosynthesis; RNA-Binding Proteins; RNA, Messenger; Transcription, Genetic | 1987 |
Why is one Bacillus alpha-amylase more resistant against irreversible thermoinactivation than another?
Topics: alpha-Amylases; Amides; Asparagine; Bacillus; Electrochemistry; Geobacillus stearothermophilus; Glutamine; Half-Life; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Lysine; Protein Conformation; Starch; Thermodynamics | 1988 |
Structural difference between the two forms of guinea-pig beta 2-microglobulin and their occurrence in inbred guinea-pig strains.
Topics: Amino Acid Sequence; Animals; Asparagine; beta 2-Microglobulin; Carboxypeptidases; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Lysine; Peptide Chain Termination, Translational | 1985 |
A new case of hemoglobin Providence (alpha 2 beta 2 82 (EF6) Lys----Asn or Asp) discovered in a French Caucasian family. Structural and functional studies.
Topics: Adolescent; Adult; Asparagine; Aspartic Acid; Child, Preschool; Female; France; Hemoglobin J; Hemoglobins, Abnormal; Humans; Kinetics; Lysine; Male; Middle Aged; Oxygen; Pedigree; Peptide Fragments; Trypsin; White People | 1985 |
Preparation and properties of smooth muscle myosin from horse esophagus.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Asparagine; Aspartic Acid; Calcium; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Edetic Acid; Enzyme Activation; Esophagus; Ethylmaleimide; Glycine; Horses; Leucine; Lysine; Magnesium; Muscle Proteins; Muscle, Smooth; Muscles; Organ Specificity; Osmolar Concentration; Phosphorus; Potassium Chloride; Proline; Rabbits; Sulfhydryl Compounds; Temperature; Ultracentrifugation | 1970 |
Synthetic substitute enzymes. II. Synthesis & catalytic properties of L-asparaginyl-L-lysyl-L-histidyl-L-histidyl-L-arginine.
Topics: Acetates; Arginine; Asparagine; Binding Sites; Catalysis; Esterases; Histidine; Hydrolysis; Lysine; Methods; Models, Structural; Peptides; Ribonucleases; RNA | 1969 |
[Development kinetics of Rous sarcoma virus (Schmidt-Ruppin strain). Estimation of arginine incorporation time into viral proteins. Electron microscope autoradiographic study].
Topics: Arginine; Asparagine; Autoradiography; Avian Sarcoma Viruses; Glutamine; Glycine; Kinetics; Lysine; Microscopy, Electron; Tritium; Uridine; Valine; Viral Proteins | 1969 |
Structure of inositol hexaphosphate--human deoxyhaemoglobin complex.
Topics: Asparagine; Binding Sites; Diphosphoglyceric Acids; Fourier Analysis; Hemoglobins; Lysine; Models, Structural; Molecular Conformation; Phosphatidylinositols; Protein Binding; X-Ray Diffraction | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Amino acid composition of proteins of the placenta and the fetal membranes in abortion].
Topics: Abortion, Spontaneous; Asparagine; Cystine; Extraembryonic Membranes; Female; Glutamine; Histidine; Humans; Lysine; Placenta; Pregnancy; Proteins; Valine | 1974 |
Tryptophan synthetase B 2 subunit. Application of genetic analysis to the study of primary structure.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Asparagine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cyanogen Bromide; Electrophoresis, Paper; Escherichia coli; Genetic Code; Hydro-Lyases; Lysine; Mutation; Operon; Peptides; Species Specificity; Trypsin; Tryptophan Synthase | 1972 |
The presence of N-(purin-6-ylcarbamoyl)threonine in transfer ribonucleic acid species whose codons begin with adenine.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Arginine; Asparagine; Benzoates; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Genetic Code; Glycolates; Isoleucine; Leucine; Lysine; Methionine; Purine Nucleotides; RNA, Bacterial; RNA, Transfer; Serine; Succinimides; Threonine; Tritium | 1972 |
[Chemical studies on colibiogen].
Topics: Alanine; Asparagine; Biological Products; Escherichia coli; Galactose; Glucose; Glutamates; Glycine; Leucine; Lysine; Palmitic Acids; Stearic Acids; Xylose | 1973 |
Ribosomal proteins. XXXVII. Determination of allelle types and amino acid exchanges in protein S12 of three streptomycin-resistant mutants of Escherichia coli.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Bacterial Proteins; Carbon Radioisotopes; Centrifugation, Zonal; Chromatography, Ion Exchange; Chromatography, Paper; Drug Resistance, Microbial; Escherichia coli; Lysine; Mutation; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Ribosomes; Species Specificity; Spectrophotometry, Ultraviolet; Streptomycin; Trypsin | 1972 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Two variants of hemoglobin D in the algerian population: hemoglobin D Ouled Rabah 19 (BI) Asn leads to Lys and hemoglobin D Iran 22 (Br) Glu leads to Gln.
Topics: Algeria; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis, Starch Gel; Globins; Glutamates; Glycine; Hemoglobins, Abnormal; Iron; Lysine; Mutation; Peptides; Trypsin | 1973 |
Comparative effect of intravenously administered nitrogenous compounds on uric acid synthesis in chickens fed a 20 per cent protein diet.
Topics: Acetates; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Chickens; Dietary Proteins; Glutamates; Glutamine; Glycine; Injections, Intravenous; Inosine; Lysine; Male; Nitrogen; Quaternary Ammonium Compounds; Sodium; Structure-Activity Relationship; Threonine; Time Factors; Uric Acid | 1973 |
On hypothesized selective pressure by u.v. on DNA base compositions.
Topics: Adenine; Asparagine; Base Sequence; DNA; Genetic Code; Lysine; Nucleotides; Phenylalanine; Radiation Effects; Thymine; Ultraviolet Rays | 1973 |
Determination of asparagine, glutamine and pyrrolidonecarboxylic acid in total enzymic hydrolysates of peptides and glycopeptides by gas-liquid chromatography.
Topics: Amino Acids; Asparagine; Chromatography, Gas; Enzymes; Esters; Fluoroacetates; Glutamine; Glycopeptides; Homoserine; Hydrolysis; Hydroxylysine; Lysine; Methods; Peptides; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1973 |
Amino-acid sequences of red-deer and roe-deer pancreatic ribonucleases.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Deer; Glycosides; Isoleucine; Lysine; Methionine; Methods; Pancreas; Ribonucleases; Species Specificity | 1973 |
Recovery of amino acids and tRNA after scintillation counting of radioactive aminoacyl-tRNA in filter paper strips.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartic Acid; Brain; Carbon Radioisotopes; Carbonates; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Evaluation Studies as Topic; Glutamates; Glutamine; Lysine; Male; Methionine; Methods; Paper; Quaternary Ammonium Compounds; RNA, Transfer; Time Factors | 1974 |
Snake venom toxins. The primary structures of two novel cytotoxin homologues from the venom of forest cobra (Naja melanoleuca).
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chromatography, DEAE-Cellulose; Disulfides; Hydrogen-Ion Concentration; Lysine; Peptide Fragments; Snakes; Spectrophotometry, Ultraviolet; Toxins, Biological; Trypsin; Venoms | 1974 |
Haemoglobin A2-NYU in the Netherlands. Incidence of delta-chain variants in human populations.
Topics: Aged; Amino Acid Sequence; Asparagine; Blood Protein Electrophoresis; Electrophoresis, Starch Gel; Female; Gene Frequency; Genetic Variation; Hemoglobins, Abnormal; Humans; Lysine; Male; Middle Aged; Mutation; Netherlands; Polymorphism, Genetic; Racial Groups | 1974 |
Hb J Sicilia: beta 65 (E9) Lys-Asn, a beta homologue of Hb Zambia.
Topics: Adult; Amino Acid Sequence; Amino Acids; Anemia; Asparagine; Blood Protein Electrophoresis; Carbohydrate Metabolism, Inborn Errors; Cell Survival; Cellulose; Chromatography, Ion Exchange; Chromium Radioisotopes; Electrophoresis, Paper; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Hemoglobins, Abnormal; Heterozygote; Humans; Lysine; Oxyhemoglobins; Peptide Fragments; Sicily; Trypsin; Zambia | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
Studies on the translation of the genetic message. II. Translation of oligonucleotide messengers of specified base sequence.
Topics: Adenine Nucleotides; Amino Acids; Ammonium Chloride; Asparagine; Carbon Isotopes; Carboxypeptidases; Cell-Free System; Chromatography; Escherichia coli; Genetic Code; Lactobacillus; Lysine; Nucleotidyltransferases; Peptides; Polynucleotides; Ribosomes; RNA, Messenger; Threonine; Tritium | 1966 |
The amino acid sequences of some tryptic peptides from porcine pepsinogen.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Asparagine; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glycine; Histidine; Leucine; Lysine; Pepsin A; Peptides; Proline; Swine; Trypsin; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Formaldehyde-induced cross-linkages in the subunit of the Escherichia coli tryptophan synthetase.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Formaldehyde; Glutamine; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Lysine; Molecular Weight; Paper; Pepsin A; Peptides; Serine; Trypsin; Tryptophan | 1971 |
Substrate specificity of elastolytic and nonelastolytic proteinases from Pseudomonas aeruginosa.
Topics: Arginine; Asparagine; Chromatography; Glutamates; Glycine; Insulin; Lysine; Pancreatic Elastase; Peptide Hydrolases; Peptides; Phenylalanine; Pseudomonas aeruginosa; Sulfonic Acids; Tyrosine | 1966 |
Hemoglobin Richmond, a human hemoglobin which forms asymmetric hybrids with other hemoglobins.
Topics: Adolescent; Adult; Amino Acid Sequence; Amino Acids; Asparagine; Black or African American; Blood Protein Electrophoresis; Buffers; Child; Chromatography, Ion Exchange; Edetic Acid; Genes; Hemoglobins, Abnormal; Humans; Hybridization, Genetic; Hydrogen-Ion Concentration; Lysine; Middle Aged; Pedigree; Peptides; Sodium Chloride; Ultracentrifugation | 1969 |
Characterization and chemical modifications of toxins isolated from the venoms of the sea snake, Laticauda semifasciata, from Philippines.
Topics: Amino Acids; Animals; Antigens; Arginine; Asparagine; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis; Hot Temperature; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Isoelectric Focusing; Lethal Dose 50; Lysine; Mice; Molecular Weight; Pyrrolidinones; Rabbits; Snakes; Sulfhydryl Compounds; Toxins, Biological; Tryptophan; Ultracentrifugation; Venoms | 1971 |
Oxygen equilibrium characteristics of abnormal hemoglobins. Hirose (alpha-2-beta-2-37Ser), L Ferrara (alpha-2-47-Gly-beta-2), Broussais (alpha-2-90-Asn-beta-2), and Dhofar (alpha-2-beta-2-58Arg).
Topics: Arginine; Asparagine; Aspartic Acid; Electrophoresis, Starch Gel; Genetic Variation; Glycine; Hemoglobins, Abnormal; Heterozygote; Humans; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Mathematics; Oxygen; Partial Pressure; Polarography; Proline; Serine; Tryptophan | 1972 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Activity and regulation of an acidic amino acid permease of Aspergillus nidulans.
Topics: Ammonia; Asparagine; Aspartic Acid; Aspergillus; Cycloheximide; Cysteine; Glutamates; Glycine; Kinetics; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylamines; Nitrates; Urea | 1971 |
[Findings concerning the decrease of amino acid content during ther heating of proteins].
Topics: Amino Acids; Asparagine; Caseins; Chromatography, Paper; Cystine; Dietary Proteins; Food; Food Analysis; Glutamates; Hot Temperature; Leucine; Lysine; Methionine; Time Factors; Valine | 1971 |
An effect of streptomycin on the biosynthesis of the coat protein of coliphage f2 by extract of E. coli.
Topics: Amino Acids; Asparagine; Coliphages; Genetic Code; Lysine; RNA, Viral; Streptomycin; Viral Proteins | 1965 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Immunosuppressive effects of L-asparaginase.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine | 1970 |
Three-dimensional structure of abnormal human haemoglobins Kansas and Richmond.
Topics: Asparagine; Hemoglobins, Abnormal; Humans; Lysine; Models, Structural; Mutation; Threonine; X-Ray Diffraction | 1971 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Direction of reading of the genetic message.
Topics: Asparagine; Carboxypeptidases; Chromatography; Escherichia coli; Genetic Code; In Vitro Techniques; Lactobacillus; Lysine; Peptide Biosynthesis; Polynucleotides | 1965 |
Direction of reading of the genetic message. II.
Topics: Asparagine; Carboxypeptidases; Chromatography, Gel; Escherichia coli; Genetic Code; In Vitro Techniques; Lactobacillus; Lysine; Peptide Biosynthesis; Polynucleotides; Ribosomes; Threonine | 1966 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
Abnormal haemoglobins in Zambia. A new haemoglobin Zambia alpha-60 (E9) lysine--asparagine.
Topics: Adult; Anemia, Sickle Cell; Asparagine; Blood Protein Electrophoresis; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Infant; Lysine; Thalassemia; Zambia | 1969 |
Brucella organisms isolated from dogs: comparison of characteristics of members of the genus Brucella.
Topics: Abortion, Veterinary; Alanine; Animals; Arabinose; Arginine; Asparagine; Brucella; Brucellosis; Citrulline; Culture Media; Dog Diseases; Dogs; Female; Galactose; Glutamates; Hematoma; Humans; Lysine; Ornithine; Pregnancy; Ribose; Xylose | 1969 |
Mechanisms of heat damage in proteins. 2. Chemical changes in pure proteins.
Topics: Albumins; Ammonia; Asparagine; Chemical Phenomena; Chemistry; Cystine; Glutamine; Hot Temperature; Isoleucine; Lysine; Protein Denaturation; Serum Albumin, Bovine; Sulfides | 1970 |
Hemoglobin Broussais: alpha-90 lys changed to asn.
Topics: Amino Acids; Asparagine; Autoanalysis; Blood Protein Electrophoresis; Female; Globins; Hemoglobins, Abnormal; Humans; Infant; Lysine; Male; Peptides; Saskatchewan; Trypsin | 1970 |
Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and gamma-glutamyl transfer.
Topics: Acyltransferases; Alanine; Amino Acids; Animals; Asparagine; Brain; Chemical Phenomena; Chemistry; Formates; Glutamine; Glycine; Kinetics; Ligases; Liver; Lysine; Phenylalanine; Rats; Sheep; Tyrosine | 1970 |
[The qualitative and quantitative demonstration of free amino acids in tonsil tissue with the use of paper chromatography].
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Asparagine; Child; Child, Preschool; Chromatography, Paper; Glutamine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Methods; Middle Aged; Palatine Tonsil; Phenylalanine; Valine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
A human myoglobin variant 133 (H-10)lysine--asparagine.
Topics: Aged; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Cyanides; Electrophoresis; Genetic Variation; Humans; Lysine; Male; Muscles; Myoglobin; Peptides; Trypsin | 1971 |
Malic dehydrogenase. IX. Primary structure of tryptic peptides from pig heart supernatant enzyme.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Histidine; Imines; Lysine; Malate Dehydrogenase; Methods; Myocardium; Peptides; Threonine; Tritium; Trypsin; Tryptophan | 1971 |
Solic phase synthetic study of the active site region of staphylococcal nuclease-T'.
Topics: Amides; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Calcium; Chemical Phenomena; Chemistry; Chromatography, Paper; Citrulline; Deoxyribonucleases; Electrophoresis; Fluorescence; Glutamates; Lysine; Models, Structural; Peptides; Protein Binding; Ribonucleases; Spectrum Analysis; Staphylococcus; Trypsin | 1971 |
Abnormal encystment after the action of certain amino-acids.
Topics: Amino Acids; Amoeba; Animals; Asparagine; Cystine; Isoleucine; Lysine; Tryptophan | 1971 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The action of sparsomycin and gougerotin on virus growth.
Topics: Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Carbon Isotopes; Encephalitis Viruses; Glycine; Herpesviridae; Influenza A virus; Leucine; Lysine; Molecular Biology; Newcastle disease virus; Phenylalanine; Proline; RNA, Messenger; Vaccinia virus; Virus Replication; Viruses | 1968 |
Haemoglobin Stanleyville II (alpha asparagine replaced by lysine).
Topics: Adolescent; Amino Acid Sequence; Asparagine; Blood Protein Electrophoresis; Chromatography, Ion Exchange; Female; Hemoglobins, Abnormal; Humans; Lysine | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver.
Topics: Amino Acids; Animals; Arginine; Asparagine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Perfusion; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Tryptophan; Valine | 1969 |
Hemoglobin G Szuhu: beta80 Asn replaced by Lys.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography, Ion Exchange; Electrophoresis; Glutamates; Glycine; Hemoglobins, Abnormal; Humans; Lysine; Male; Peptides; Taiwan; Trypsin | 1969 |
Hemoglobin NYU, a delta chain variant, alpha 2 delta 2 lys.
Topics: Adolescent; Asparagine; Blood Protein Disorders; Blood Protein Electrophoresis; Chemical Phenomena; Chemistry; Chromatography; Female; Gels; Hemoglobins, Abnormal; Humans; Israel; Jews; Lysine; Male; New York City; Pedigree; Protein Hydrolysates; Starch; Thalassemia | 1969 |
Phenotypic comparison of Brucella ovis to the DNA-homologous Brucella species.
Topics: Alanine; Arabinose; Arginine; Asparagine; Brucella; Citrulline; Culture Media; DNA, Bacterial; Galactose; Glutamates; Lysine; Ornithine; Phenotype; Ribose; Xylose | 1969 |
[Amino acid content in the cerebrospinal fluid in epilepsy].
Topics: Amino Acids; Ammonia; Asparagine; Chromatography, Ion Exchange; Epilepsy; Glutamates; Histidine; Humans; In Vitro Techniques; Lysine | 1965 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Photochemical synthesis of amino acids from paraformaldehyde catalyzed by inorganic agents.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Catalysis; Chemistry, Organic; Chromatography, Paper; Cobalt; Copper; Formaldehyde; Iron; Leucine; Light; Lysine; Nitrates; Organic Chemistry Phenomena; Quaternary Ammonium Compounds; Sulfides; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Enzymatic trimethylation of residue-72 lysine in cytochrome c. Effect on the total structure.
Topics: Animals; Asparagine; Chemical Phenomena; Chemistry; Cytochrome c Group; Histone-Lysine N-Methyltransferase; Horses; Hydrogen Bonding; Isoelectric Focusing; Isoelectric Point; Lysine; Methylation; Models, Molecular; Neurospora crassa; Protein Methyltransferases; Saccharomyces cerevisiae; Species Specificity | 1980 |
Hb Albany-Suma (alpha 11 [A9] Lys----Asn), a hemoglobin variant with slightly elevated oxygen affinity in Japan.
Topics: Aged; Amino Acids; Asparagine; Blood Protein Electrophoresis; Chromatography; Electrophoresis, Starch Gel; Goiter; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Japan; Lysine; Male; Oxygen | 1984 |
On the aggregation of cells during growth and its effect on the isolation of auxotrophic mutants of Bacillus brevis ATCC 10068.
Topics: Asparagine; Bacillus; Culture Media; Glycerol; Histidine; Lysine; Methionine; Mutation; Penicillins; Peptones | 1984 |
"Two out of three" codon reading leading to mistranslation in vivo.
Topics: Asparagine; Codon; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Isoelectric Focusing; Lysine; Protein Biosynthesis; Ribosomal Protein S9; RNA, Messenger; RNA, Ribosomal | 1980 |
Mistranslation in cells infected with the bacteriophage MS2: direct evidence of Lys for Asn substitution.
Topics: Asparagine; Capsid; Codon; Coliphages; Escherichia coli; Genetic Code; Lysine; Protein Biosynthesis; RNA Phages; RNA, Viral; Viral Proteins | 1980 |
[Clinical and biological studies of an hybrid S/Stanleyville II hemoglobin (alpha 2 78 Asn replaced by Lys beta 2 6 Glu replaced by Val) (author's transl)].
Topics: Adult; Asparagine; Blood Protein Electrophoresis; Female; Glutamates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Heterozygote; Humans; Hybridization, Genetic; Lysine; Pedigree; Valine | 1980 |
A further example of hemoglobin Hikari (beta 61[E5] Lys replaced by Asn).
Topics: Aged; Asparagine; Electrophoresis, Starch Gel; Female; Genetic Variation; Hemoglobin A; Hemoglobins, Abnormal; Humans; Lysine; Male; Pedigree | 1981 |
Identification of hemoglobin G-Philadelphia (alpha 68 Asn replaced by Lys) and hemoglobin Matsue-Oki (alpha 75 Asp replaced by Asn) in a black infant.
Topics: Adolescent; Adult; Asparagine; Aspartic Acid; Black People; Child; Female; Genetic Carrier Screening; Genetic Variation; Hemoglobins, Abnormal; Humans; Infant; Lysine; Male; Mutation; Pedigree; Peptide Fragments; Thalassemia | 1982 |
Effects of unilateral nephrectomy on erythrocytosis and arteriosclerosis induced in rats by intrarenal injection of nickel subsulfide.
Topics: Animals; Arteriosclerosis; Asparagine; Glycine; Histidine; Lysine; Male; Nephrectomy; Nickel; Polycythemia; Rats; Rats, Inbred F344; Time Factors | 1982 |
A novel mutation in exon 3 of the proteolipid protein gene in Pelizaeus-Merzbacher disease.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Child, Preschool; Diffuse Cerebral Sclerosis of Schilder; DNA Primers; Exons; Female; Humans; Lysine; Male; Molecular Sequence Data; Myelin Proteins; Myelin Proteolipid Protein; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic | 1995 |
Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the delta- and mu-opioid receptors.
Topics: Amino Acid Sequence; Analgesics; Animals; Asparagine; Binding Sites; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Kinetics; Lysine; Molecular Sequence Data; Morphine; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Proteins | 1995 |
Proton transfer in cytochrome bo3 ubiquinol oxidase of Escherichia coli: second-site mutations in subunit I that restore proton pumping in the mutant Asp135-->Asn.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Electron Transport; Electron Transport Complex IV; Escherichia coli; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Proton Pumps; Structure-Activity Relationship | 1995 |
Purification and characterization of a CM-glycinin digesting protease from soybean seeds.
Topics: Alanine; Amino Acid Sequence; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Globulins; Glycine max; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Molecular Sequence Data; Molecular Weight; Plant Proteins, Dietary; Seeds; Soybean Proteins; Tyrosine | 1993 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Three new mutations of thyroid hormone receptor-beta associated with resistance to thyroid hormone.
Topics: Adolescent; Adult; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Drug Resistance; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Lysine; Male; Molecular Sequence Data; Point Mutation; Receptors, Thyroid Hormone; Sicily; Syndrome; Thyroid Hormones | 1994 |
Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.
Topics: Acetylation; Amino Acids; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutamates; Glutamine; Humans; Lysine; Mass Spectrometry; Regression Analysis; Serine | 1994 |
Ocular findings in patients with autosomal dominant retinitis pigmentosa and transversion mutation in codon 244 (Asn244Lys) of the peripherin/RDS gene.
Topics: Adult; Asparagine; Base Sequence; Child; Codon; Female; Genes, Dominant; Humans; Intermediate Filament Proteins; Lysine; Male; Membrane Glycoproteins; Middle Aged; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neuropeptides; Pedigree; Peripherins; Retinitis Pigmentosa | 1994 |
Structure requirements for disulfide bridge sulfitolysis of oxidized Escherichia coli thioredoxin studied by fluorescence spectroscopy.
Topics: Amino Acid Sequence; Asparagine; Disulfides; Escherichia coli; Lysine; Molecular Sequence Data; Molecular Structure; Mutation; Spectrometry, Fluorescence; Sulfites; Thioredoxins | 1994 |
Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin.
Topics: Asparagine; Histidine; Humans; Lysine; Mutagenesis, Site-Directed; Mutation; Myoglobin; Nitric Oxide; Photolysis; Structure-Activity Relationship; Thermodynamics; Valine | 1994 |
In vitro aging of calmodulin generates isoaspartate at multiple Asn-Gly and Asp-Gly sites in calcium-binding domains II, III, and IV.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Binding Sites; Brain Chemistry; Calcium; Calmodulin; Cattle; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Lysine; Methylation; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Time Factors; Trypsin | 1993 |
The influence of the nature of the asparagine 289-linked oligosaccharide on the activation by urokinase and lysine binding properties of natural and recombinant human plasminogens.
Topics: Animals; Asparagine; Enzyme Activation; Glycoproteins; Humans; In Vitro Techniques; Kinetics; Lysine; Moths; Oligosaccharides; Plasminogen; Recombinant Proteins; Structure-Activity Relationship; Urokinase-Type Plasminogen Activator | 1993 |
Fibrinogen Bern I: substitution gamma 337 Asn-->Lys is responsible for defective fibrin monomer polymerization.
Topics: Adult; Aged; Amino Acid Sequence; Asparagine; Base Sequence; DNA; DNA Primers; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Fibrinopeptide A; Fibrinopeptide B; Genetic Variation; Humans; Kinetics; Lysine; Male; Molecular Sequence Data; Nuclear Family; Oligonucleotides, Antisense; Point Mutation; Polymerase Chain Reaction | 1993 |
Isolation and in vitro characterization of CheZ suppressors for the Escherichia coli chemotactic response regulator mutant CheYN23D.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Base Sequence; Chemotaxis; DNA Primers; Escherichia coli; Escherichia coli Proteins; Lysine; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins; Suppression, Genetic | 1996 |
A structural study of the carboxyl terminal region of the human erythrocyte band 3 protein.
Topics: Alanine; Amino Acid Sequence; Anion Exchange Protein 1, Erythrocyte; Asparagine; Cyanogen Bromide; Erythrocyte Membrane; Humans; Lysine; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Sequence Homology, Amino Acid; Sodium Hydroxide; Trypsin; Valine | 1995 |
Unaccustomed high-mileage vs intensity training-related changes in performance and serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cystine; Erythrocyte Count; Exercise Test; Fatigue; Glycine; Hematocrit; Hemoglobins; Humans; Lactates; Leukocyte Count; Lysine; Methionine; Phenylalanine; Physical Endurance; Prospective Studies; Running; Serine; Taurine; Tryptophan; Tyrosine | 1996 |
Role of VP2 amino acid 141 in tropism of Theiler's virus within the central nervous system.
Topics: Animals; Asparagine; Capsid; Capsid Proteins; Cell Line; Central Nervous System; Cricetinae; Demyelinating Diseases; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Mutagenesis, Site-Directed; Poliomyelitis; RNA, Viral; Spinal Cord; Theilovirus | 1996 |
Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition.
Topics: Animals; Asparagine; Aspartic Acid; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Humans; Kinetics; Lysine; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Neuropeptides; Neurotransmitter Agents; Rats; Reserpine; Serotonin; Structure-Activity Relationship; Substrate Specificity; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 1997 |
Mutant RecA proteins which form hexamer-sized oligomers.
Topics: Arginine; Asparagine; Bacteria; Chromatography, Liquid; Crystallography, X-Ray; DNA Repair; Lysine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Rec A Recombinases; Tyrosine | 1997 |
Recombinant sickle hemoglobin containing a lysine substitution at Asp-85(alpha): expression in yeast, functional properties, and participation in gel formation.
Topics: Asparagine; Gene Expression; Hemoglobin, Sickle; Humans; Lysine; Mutation; Plasmids; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae | 1997 |
Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Lysine; Microtubules; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Structure-Activity Relationship; tau Proteins | 1997 |
Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium Gordona bronchialis (Rhodococcus bronchialis).
Topics: Acetylene; Asparagine; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Pyruvates; Rhodococcus | 1997 |
Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity.
Topics: Animals; Asparagine; Crystallography, X-Ray; DNA; Drosophila; Homeodomain Proteins; Hydrogen Bonding; Lysine; Models, Molecular; Mutation; Nucleic Acid Conformation; Protein Conformation; Transcription Factors | 1997 |
The Gln223Arg and Lys656Asn polymorphisms in the human leptin receptor do not associate with traits related to obesity.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Asparagine; Blood Glucose; Body Constitution; Body Mass Index; Carrier Proteins; Female; Glutamine; Heterozygote; Homozygote; Humans; Insulin; Lysine; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Leptin; Reference Values; Socioeconomic Factors | 1997 |
Contribution of Arg288 of Escherichia coli elongation factor Tu to translational functionality.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Conserved Sequence; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; Recombinant Proteins; Ribosomes; RNA, Transfer, Phe; Thermus | 1997 |
Regulatory phosphorylation of plant phosphoenolpyruvate carboxylase: role of a conserved basic residue upstream of the phosphorylation site.
Topics: Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Enzyme Activation; Enzyme Inhibitors; Glucose-6-Phosphate; Lysine; Malates; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxylase; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Zea mays | 1997 |
Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
Topics: Animals; Asparagine; Batrachotoxins; Cell Line; Cell Membrane; Humans; Lysine; Macromolecular Substances; Membrane Potentials; Models, Molecular; Muscle, Skeletal; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Protein Conformation; Rats; Recombinant Proteins; Sodium Channels; Transfection; Veratridine | 1998 |
Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression.
Topics: Alanine Transaminase; Amino Acid Isomerases; Asparagine; Culture Media; D-Alanine Transaminase; Escherichia coli; Gene Expression; Glutamic Acid; Lysine; Mutagenesis, Site-Directed | 1998 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Glutamine; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Ligands; Lysine; Mutagenesis, Site-Directed; Polymerase Chain Reaction | 1998 |
Genetic variation in human serum albumin: a 313 Lys-->Asn mutation in albumin reading identified by PCR analysis.
Topics: Aged; Amino Acid Sequence; Asparagine; Cyanogen Bromide; DNA; Female; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Point Mutation; Polymerase Chain Reaction; Serum Albumin; Trypsin | 1998 |
L-arginine binding to liver arginase requires proton transfer to gateway residue His141 and coordination of the guanidinium group to the dimanganese(II,II) center.
Topics: Animals; Arginase; Arginine; Asparagine; Binding Sites; Borates; Citrulline; Electron Spin Resonance Spectroscopy; Guanidine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Liver; Lysine; Manganese; Mutagenesis, Site-Directed; Ornithine; Protons; Rats; Substrate Specificity | 1998 |
His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Histidine; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ribonuclease, Pancreatic; Structure-Activity Relationship | 1998 |
Glu78, from the conserved PEWY sequence of subunit IV, has a key function in cytochrome b6f turnover.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Transformation, Genetic | 1998 |
Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; Asparagine; Base Composition; Cell Line; Chlorocebus aethiops; DNA Helicases; DNA Primase; DNA Replication; Drug Resistance, Microbial; Enzyme Inhibitors; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Lysine; Molecular Sequence Data; Mutagenesis; Sequence Homology, Amino Acid; Spodoptera; Thiazoles; Vero Cells; Viral Proteins; Virus Replication | 1998 |
Oligosaccharide configuration of fibrinogen Kaiserslautern: electrospray ionisation analysis of intact gamma chains.
Topics: Amino Acid Substitution; Asparagine; Carbohydrate Conformation; Fibrinogen; Homozygote; Humans; Lysine; Mass Spectrometry; Models, Molecular; N-Acetylneuraminic Acid; Oligosaccharides; Point Mutation | 1998 |
Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.
Topics: Animals; Aprotinin; Asparagine; Aspartic Acid; Cattle; Coumarins; Enzyme Activation; Enzyme Stability; Histidine; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Oligopeptides; Peptide Fragments; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Substrate Specificity; Trypsin; Trypsinogen | 1998 |
Use of site-directed mutagenesis to identify residues specific for each reaction catalyzed by chorismate mutase-prephenate dehydrogenase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Chorismate Mutase; Circular Dichroism; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Prephenate Dehydrogenase; Recombinant Proteins | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
A K319N/E325Q double mutant of the lactose permease cotransports H+ with lactose. Implications for a proposed mechanism of H+/lactose symport.
Topics: Alanine; Amino Acid Substitution; Asparagine; Biological Transport; Codon; Escherichia coli; Escherichia coli Proteins; Glutamine; Hydrogen; Kinetics; Lactose; Lysine; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Symporters | 1999 |
The presence of pseudouridine in the anticodon alters the genetic code: a possible mechanism for assignment of the AAA lysine codon as asparagine in echinoderm mitochondria.
Topics: Amino Acid Substitution; Animals; Anticodon; Asparagine; Base Sequence; Echinodermata; Genetic Code; Lysine; Mitochondria; Molecular Sequence Data; Nucleic Acid Conformation; Protein Biosynthesis; Pseudouridine; RNA, Transfer | 1999 |
[Gly380Arg and Asn540Lys mutations of fibroblast growth factor receptor 3 in achondroplasia and hypochndroplasia in the Spanish population].
Topics: Achondroplasia; Arginine; Asparagine; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 4; Genetic Counseling; Glycine; Humans; Lysine; Osteochondrodysplasias; Phenotype; Point Mutation; Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; RNA, Transfer, Amino Acid-Specific; Spain | 1999 |
Identification of Hb J-Buda [alpha61(E10)Lys-->Asn] in a Thai female.
Topics: Asparagine; Female; Hemoglobins, Abnormal; Humans; Lysine; Point Mutation; Thailand | 1999 |
Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperatures.
Topics: Adaptation, Physiological; Asparagine; Crystallography, X-Ray; Enzyme Stability; Geobacillus stearothermophilus; Glycine; Hot Temperature; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Structure-Activity Relationship; Triose-Phosphate Isomerase | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Topics: Aminobutyrates; Asparagine; Binding Sites; Computer Simulation; Crystallography, X-Ray; HIV Protease Inhibitors; HIV-1; Isoleucine; Leucine; Lysine; Models, Molecular; Molecular Mimicry; Oligopeptides; Peptides, Cyclic; Phenylalanine; Protein Conformation; Stereoisomerism; Valine | 1999 |
Steady-state kinetic characterization of RB69 DNA polymerase mutants that affect dNTP incorporation.
Topics: Alanine; Asparagine; Bacteriophage T4; Deoxyguanine Nucleotides; Dinucleoside Phosphates; DNA-Directed DNA Polymerase; Enzyme Activation; Exodeoxyribonucleases; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Substrate Specificity; Tyrosine; Viral Proteins | 1999 |
Effects of substitutions of lysine and aspartic acid for asparagine at beta 108 and of tryptophan for valine at alpha 96 on the structural and functional properties of human normal adult hemoglobin: roles of alpha 1 beta 1 and alpha 1 beta 2 subunit inter
Topics: 2,3-Diphosphoglycerate; Adult; Amino Acid Substitution; Asparagine; Aspartic Acid; Buffers; Chlorides; Hemoglobin A; Hemoglobins; Hemoglobins, Abnormal; HEPES; Humans; Lysine; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Oxyhemoglobins; Phosphates; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Tryptophan; Valine | 1999 |
Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Biophysical Phenomena; Biophysics; Chloride Channels; Drosophila; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Permeability; Point Mutation; Protein Conformation; Rats; Static Electricity; Xenopus laevis | 1999 |
Probing the diphosphoglycerate binding pocket of HbA and HbPresbyterian (beta 108Asn --> Lys).
Topics: 2,3-Diphosphoglycerate; Asparagine; Binding Sites; Carboxyhemoglobin; Hemoglobin A; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Nitrophenols; Pyrenes; Spectrometry, Fluorescence; Titrimetry | 1999 |
Recombinant hemoglobin(alpha 29leucine --> phenylalanine, alpha 96valine --> tryptophan, beta 108asparagine --> lysine) exhibits low oxygen affinity and high cooperativity combined with resistance to autoxidation.
Topics: Amino Acid Substitution; Asparagine; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Humans; Kinetics; Leucine; Lysine; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Phenylalanine; Protein Binding; Recombinant Proteins; Tryptophan; Valine | 1999 |
Degradation signals in the lysine-asparagine sequence space.
Topics: Amino Acid Sequence; Asparagine; beta-Galactosidase; Fungal Proteins; Hemagglutinins; Kinetics; Ligases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Proteins; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetrahydrofolate Dehydrogenase; Ubiquitin-Protein Ligases | 1999 |
Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase.
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Catalytic Domain; Computer Simulation; Formycins; Glutamine; Kinetics; Lysine; Mice; Models, Molecular; Purine-Nucleoside Phosphorylase; Substrate Specificity | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Effect of lysine residues on the deamidation reaction of asparagine side chains.
Topics: Amides; Amino Acid Sequence; Asparagine; Isomerism; Lysine; Peptides, Cyclic | 2000 |
Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein.
Topics: Adenoviruses, Human; Animals; Asparagine; Binding Sites; Capsid; Capsid Proteins; CHO Cells; Circular Dichroism; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cricetinae; Humans; Leucine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Virus | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
D-LysAsnProTyr tetrapeptide: a novel B-cell stimulant and stabilized bursin mimetic.
Topics: Animals; Asparagine; B-Lymphocyte Subsets; Cells, Cultured; Female; Half-Life; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Molecular Mimicry; Oligopeptides; Proline; Spleen; Tyrosine | 2000 |
Histidine 450 plays a critical role in catalysis and, with Ca2+, contributes to the substrate specificity of aminopeptidase A.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Asparagine; Calcium; Catalysis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutamates; Glutamyl Aminopeptidase; Histidine; Humans; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Organophosphonates; Rats; Recombinant Proteins; Substrate Specificity; Sulfhydryl Compounds | 2000 |
Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epidermal growth factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carbohydrate Sequence; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Glycosylation; Humans; Lysine; Molecular Sequence Data; Oligosaccharides; Recombinant Proteins; Transfection | 2000 |
Identification of a dysfibrinogen, the substitution of gamma308Asn(AAT) to Lys(AAG), using coagulation tests, immunoblot analysis, and allele-specific polymerase chain reaction.
Topics: Alleles; Amino Acid Substitution; Asparagine; Base Sequence; Blood Coagulation Tests; Blotting, Western; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Fibrinogens, Abnormal; Humans; Lysine; Male; Polymerase Chain Reaction | 2000 |
Identification of mutations in rat CD59 that increase the complement regulatory activity.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Asparagine; Binding Sites, Antibody; CD59 Antigens; Cell Line; CHO Cells; Complement Inactivator Proteins; Complement Membrane Attack Complex; Complement Pathway, Classical; Cricetinae; Glutamic Acid; Humans; Lysine; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Rabbits; Rats; Recombinant Proteins; Transfection | 2000 |
Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene.
Topics: Amino Acid Substitution; Asparagine; Codon; Dementia; Diagnosis, Differential; Frontal Lobe; Humans; Lysine; Male; Microscopy, Electron; Middle Aged; Motor Neurons; Mutation, Missense; Neurologic Examination; Neuropsychological Tests; Parkinsonian Disorders; Pedigree; Pyramidal Tracts; Retrospective Studies; tau Proteins; Temporal Lobe | 2000 |
Identification of mutations in the glucose-6-phosphatase gene in Czech and Slovak patients with glycogen storage disease type ia, including novel mutations K76N, V166A and 540del5.
Topics: Alanine; Amino Acid Substitution; Asparagine; Czech Republic; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; Humans; Lysine; Mutation; Sequence Deletion; Slovakia; Valine | 2000 |
An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-2 Receptor Agonists; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Cattle; Cell Membrane; CHO Cells; Cricetinae; Epinephrine; Genetic Variation; GTP-Binding Protein alpha Subunits, Gi-Go; Guinea Pigs; Humans; Inositol Phosphates; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Polymorphism, Genetic; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Swine; Transfection | 2000 |
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cations; Crystallography, X-Ray; Cyclic AMP Response Element-Binding Protein; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrons; Escherichia coli; Glutamic Acid; Glutamine; Hydrogen Bonding; Ions; Kinetics; Leucine Zippers; Lysine; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Response Elements; Sequence Homology, Amino Acid; Signal Transduction; Somatostatin | 2000 |
Topologically linked protein rings in the bacteriophage HK97 capsid.
Topics: Asparagine; Capsid; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Hydrogen Bonding; Lysine; Models, Molecular; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Siphoviridae | 2000 |
Evaluation of the role of two conserved active-site residues in beta class glutathione S-transferases.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Arginine; Asparagine; Binding Sites; Catalysis; Conserved Sequence; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Guanidine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteus mirabilis; Rifamycins; Spectrometry, Fluorescence; Temperature; Time Factors | 2000 |
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Topics: Animals; Arginine; Asparagine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyribonucleotides; DNA Polymerase beta; DNA-Binding Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Templates, Genetic | 2000 |
Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice.
Topics: Amino Acid Substitution; Animals; Asparagine; Cattle; Female; Genetic Engineering; Glutamine; Lactation; Lysine; Lysostaphin; Mammary Glands, Animal; Mastitis, Bovine; Mice; Mice, Transgenic; Milk; Recombinant Proteins; Staphylococcal Infections; Staphylococcus | 2001 |
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Topics: Arginine; Asparagine; Aspartate Aminotransferases; Catalytic Domain; Crystallography, X-Ray; Dicarboxylic Acids; DNA Mutational Analysis; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Lysine; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Static Electricity; Structure-Activity Relationship | 2001 |
Poly(amino acid) bioadhesives for tissue repair.
Topics: Adhesiveness; Amino Acids; Animals; Asparagine; Aspartic Acid; Biocompatible Materials; Cartilage; Cattle; Chondroitin Sulfates; Glass; Glutamic Acid; Hydrogen Bonding; Lysine; Materials Testing; Models, Chemical; Models, Molecular; Permeability; Tissue Adhesions; Tissue Adhesives; Wound Healing; Wounds and Injuries | 2000 |
Mechanism of phosphoryl transfer by nucleoside diphosphate kinase pH dependence and role of the active site Lys16 and Tyr56 residues.
Topics: Adenosine Triphosphate; Animals; Asparagine; Catalysis; Crystallography, X-Ray; Dictyostelium; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Phosphorus; Protein Conformation; Structure-Activity Relationship; Tyrosine | 2001 |
Characterization of the active-site residues asparagine 167 and lysine 161 of the IMP-1 metallo beta-lactamase.
Topics: Asparagine; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Zinc | 2001 |
Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.
Topics: Alanine; Allosteric Regulation; Asparagine; Aspartic Acid; Cations, Monovalent; Deuterium; Dimerization; Enzyme Activation; Kinetics; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Potassium; Quaternary Ammonium Compounds; Salmonella typhimurium; Salts; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Threonine; Titrimetry; Tryptophan Synthase | 2001 |
Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance.
Topics: Adenine; Alanine; Amino Acid Sequence; Asparagine; Base Pairing; Biosensing Techniques; Circular Dichroism; DNA-Binding Proteins; Kinetics; Lysine; Models, Chemical; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Peptides; Polydeoxyribonucleotides; Protein Binding; Protein Structure, Secondary; Thymine | 2001 |
Are the parameters of various stabilization factors estimated from mutant human lysozymes compatible with other proteins?
Topics: Amino Acid Substitution; Arginine; Asparagine; Bacteriophage T4; Calorimetry, Differential Scanning; Crystallography, X-Ray; Enzyme Stability; Humans; Lysine; Muramidase; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteins; Thermodynamics | 2001 |
Asn to Lys mutations at three sites which are N-glycosylated in the mammalian protein decrease the aggregation of Escherichia coli-derived erythropoietin.
Topics: Amino Acid Substitution; Amino Acids; Asparagine; Binding Sites, Antibody; Biological Assay; Circular Dichroism; Erythropoietin; Escherichia coli; Glycosylation; Hot Temperature; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Receptors, Erythropoietin; Temperature | 2001 |
Molecular characterization of a rare hemoglobin variant: Hb-Hinsdale: beta139(H17)ASN-->Lys.
Topics: Asparagine; Female; Hemoglobins, Abnormal; Humans; Lysine; Point Mutation | 2001 |
Proton transfer in Azotobacter vinelandii ferredoxin I: entatic Lys84 operates as elastic counterbalance for the proton-carrying Asp15.
Topics: Asparagine; Aspartic Acid; Azotobacter vinelandii; Energy Metabolism; Ferredoxins; Lysine; Models, Molecular; Mutation; Protein Conformation; Proton Pumps | 2001 |
Structural adaptation of enzymes to low temperatures.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Asparagine; Catalysis; Cold Temperature; Enzyme Stability; Enzymes; Eukaryotic Cells; Lysine; Models, Chemical; Prokaryotic Cells; Protein Engineering; Protein Structure, Secondary; Sequence Alignment; Sequence Analysis, Protein; Structure-Activity Relationship; Thermodynamics | 2001 |
Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Cell Membrane; Conserved Sequence; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation, Fungal; Lysine; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Protein Folding; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Temperature; Threonine | 2001 |
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Catalysis; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Parabens; Phenylalanine; Riboflavin; Serine; Spectrophotometry; Substrate Specificity; Tyrosine | 2001 |
Identification of the myotoxic site of the Lys49 phospholipase A(2) from Agkistrodon piscivorus piscivorus snake venom: synthetic C-terminal peptides from Lys49, but not from Asp49 myotoxins, exert membrane-damaging activities.
Topics: Agkistrodon; Amino Acid Sequence; Animals; Anticoagulants; Asparagine; Bothrops; Cell Line; Cell Survival; Cells, Cultured; Creatine Kinase; Crotalid Venoms; Edema; Heparin; Injections, Intramuscular; Injections, Subcutaneous; L-Lactate Dehydrogenase; Lysine; Membranes; Mice; Muscle, Skeletal; Necrosis; Phospholipases A; Protein Binding; Protein Isoforms; Structure-Activity Relationship | 2001 |
A phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
Topics: Amino Acid Motifs; Animals; Asparagine; Batrachotoxins; Cells, Cultured; Drug Interactions; Humans; Insecticides; Isoleucine; Lysine; Methionine; Mutagenesis, Site-Directed; Nitriles; Patch-Clamp Techniques; Phenylalanine; Pyrethrins; Rats; Sodium Channels; Transfection | 2001 |
Four casein kinase I isoforms are differentially partitioned between nucleus and cytoplasm.
Topics: 3T3 Cells; Alternative Splicing; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Blotting, Western; Casein Kinases; Cell Nucleus; COS Cells; Cytoplasm; Cytoskeleton; Green Fluorescent Proteins; Luminescent Proteins; Lysine; Mice; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nuclear Localization Signals; Phosphorylation; Plasmids; Protein Binding; Protein Isoforms; Protein Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Transfection | 2001 |
Determinants of T box protein specificity.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Embryo, Nonmammalian; Female; Fetal Proteins; Gene Expression Regulation, Developmental; Lysine; Molecular Sequence Data; Point Mutation; Repetitive Sequences, Nucleic Acid; Sequence Homology, Amino Acid; Substrate Specificity; T-Box Domain Proteins; Xenopus; Xenopus Proteins | 2001 |
Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.
Topics: Alanine; Animals; Arginine; Asparagine; Binding Sites; Calcium; Cell Line; Cell Membrane; COS Cells; Enzyme Activation; Humans; Isoenzymes; Liposomes; Lysine; Micelles; Mutagenesis, Site-Directed; Phosphatidylserines; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Protein Transport; Threonine | 2001 |
Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association.
Topics: Arrestins; Asparagine; beta-Arrestins; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP; Cytoplasm; DNA, Complementary; Endocytosis; Green Fluorescent Proteins; Humans; Immunoblotting; Kinetics; Ligands; Luminescent Proteins; Lysine; Microscopy, Confocal; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Parathyroid Hormone; Signal Transduction; Time Factors | 2002 |
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Electrophoresis, Polyacrylamide Gel; Frizzled Receptors; Glycosylation; Heparin; Humans; Lysine; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Netrin Receptors; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Proteins; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subtilisin; Time Factors; Xenopus | 2002 |
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.
Topics: Arginine; Asparagine; Binding Sites; Catalytic Domain; Crystallography, X-Ray; DNA; DNA-Formamidopyrimidine Glycosylase; Electrons; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen Bonding; Lysine; Methionine; Models, Molecular; Mutation; N-Glycosyl Hydrolases; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Protein Binding; Static Electricity | 2002 |
Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
Topics: Adenosylhomocysteinase; Animals; Apoenzymes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cattle; Circular Dichroism; Crystallography, X-Ray; DNA, Complementary; Escherichia coli; Holoenzymes; Hydrolases; Hydrolysis; Kinetics; Liver; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Protein Binding; Rats; Time Factors; Ultraviolet Rays | 2002 |
Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Animals; Asparagine; Circular Dichroism; Exons; Fungal Proteins; Glutamine; Hemoglobins; Humans; Hydrogen-Ion Concentration; Light; Lysine; Mice; Mice, Transgenic; Molecular Sequence Data; Peptide Fragments; Peptide Termination Factors; Peptides; Prions; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Scattering, Radiation; Thermodynamics; Ultraviolet Rays; X-Ray Diffraction | 2002 |
Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding.
Topics: Adult; Apolipoproteins B; Asparagine; Cell Line; Cholesterol, LDL; DNA Mutational Analysis; Enzyme-Linked Immunosorbent Assay; Exons; Female; Gene Frequency; Heterozygote; Humans; Lasers; Lysine; Male; Middle Aged; Mutation, Missense; Pedigree; Phenotype; Polymorphism, Restriction Fragment Length; Protein Binding; Receptors, LDL | 2002 |
Clinical features and disease haplotypes of individuals with the N279K tau gene mutation: a comparison of the pallidopontonigral degeneration kindred and a French family.
Topics: Adult; Asparagine; Dementia; Exons; Female; Genetic Linkage; Haplotypes; Humans; Lysine; Male; Middle Aged; Mutation, Missense; Pedigree; Supranuclear Palsy, Progressive; tau Proteins | 2002 |
Discordant Human Immunodeficiency Virus Type 1 drug resistance mutations, including K103N, observed in cerebrospinal fluid and plasma.
Topics: Amino Acid Substitution; Asparagine; Drug Resistance, Microbial; HIV-1; Humans; Lysine; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral | 2002 |
Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.
Topics: 2-Propanol; Anemia, Hemolytic; Animals; Asparagine; Chromatography, High Pressure Liquid; Erythrocytes; Globins; Hemoglobins, Abnormal; Heterozygote; Homozygote; Lysine; Mice; Mice, Knockout; Models, Genetic; Mutation; Oxygen; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2002 |
[Regulating role of various amino acids in development of apoptosis in organotypic culture of the nervous and lymphoid tissue].
Topics: Amino Acids; Animals; Apoptosis; Arginine; Asparagine; Brain; Culture Techniques; Lysine; Rats; Rats, Wistar; Spleen | 2002 |
Asp1080 upstream of the calmodulin-binding domain is critical for autoinhibition of hPMCA4b.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Binding Sites; Calcium; Calcium-Transporting ATPases; Calmodulin; Catalysis; Cation Transport Proteins; Cell Membrane; COS Cells; Dose-Response Relationship, Drug; Kinetics; Lysine; Microsomes; Molecular Sequence Data; Mutation; Plasma Membrane Calcium-Transporting ATPases; Protein Binding; Protein Structure, Tertiary; Time Factors; Transfection | 2002 |
A catalytic consensus motif for D-mannitol 2-dehydrogenase, a member of a polyol-specific long-chain dehydrogenase family, revealed by kinetic characterization of site-directed mutants of the enzyme from Pseudomonas fluorescens.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Motifs; Amino Acid Sequence; Asparagine; Catalytic Domain; Conserved Sequence; Hydrogen-Ion Concentration; Isotopes; Kinetics; Lysine; Mannitol; Mannitol Dehydrogenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Pseudomonas fluorescens; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2002 |
Compound heterozygosity for Hb Korle-Bu (beta(73); Asp-Asn) and Hb E (beta(26); Glu-Lys) with a 3.7-kb deletional alpha-thalassemia in Thai patients.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Aspartic Acid; Base Sequence; Chromosome Segregation; Female; Gene Deletion; Glutamic Acid; Hemoglobin E; Hemoglobins, Abnormal; Heterozygote; Humans; Lysine; Male; Middle Aged; Pregnancy; Thailand | 2002 |
A single nucleotide polymorphism in the alternative oxidase gene among rice varieties differing in low temperature tolerance.
Topics: Asparagine; Chromosome Mapping; Genetic Variation; Lysine; Mitochondrial Proteins; Oryza; Oxidoreductases; Plant Proteins; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable; Recombinant Proteins; Temperature | 2002 |
Adenovirus type 37 binds to cell surface sialic acid through a charge-dependent interaction.
Topics: Adenoviruses, Human; Animals; Asparagine; Binding Sites; Capsid Proteins; Cell Line; Cell Membrane; CHO Cells; Chondroitin Sulfates; Cricetinae; Dermatan Sulfate; Dextran Sulfate; Glycosaminoglycans; HeLa Cells; Humans; Lysine; N-Acetylneuraminic Acid; Protein Structure, Tertiary; Receptors, Virus; Sodium Chloride; Virion | 2002 |
A heterodimerizing leucine zipper coiled coil system for examining the specificity of a position interactions: amino acids I, V, L, N, A, and K.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Chickens; Circular Dichroism; Dimerization; Isoleucine; Leucine; Leucine Zippers; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Transcription Factors; Ultracentrifugation; Valine | 2002 |
Tetratricopeptide repeat motif-mediated Hsc70-mSTI1 interaction. Molecular characterization of the critical contacts for successful binding and specificity.
Topics: 3T3 Cells; Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Circular Dichroism; Fibroblasts; Gene Deletion; Glutathione; Glutathione Transferase; Heat-Shock Proteins; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Kinetics; Lysine; Mice; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Peptides; Precipitin Tests; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sepharose; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Surface Plasmon Resonance; Time Factors | 2003 |
Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum.
Topics: Acyl Carrier Protein; Algorithms; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Computational Biology; Green Fluorescent Proteins; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Luminescent Proteins; Lysine; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Neural Networks, Computer; Organelles; Plasmodium falciparum; Protein Binding; Protein Sorting Signals; Protein Transport; Protozoan Proteins; Vacuoles | 2003 |
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
Topics: Amino Acids; Arabidopsis; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Gene Expression Regulation, Plant; Germination; Glutamic Acid; Glutamine; Hydro-Lyases; Lysine; Methionine; Mutation; Plants, Genetically Modified; Pterocarpans; Seeds; Signal Transduction; Threonine | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
The role of Lys791 and Asn792 in gastric H,K-ATPase.
Topics: Amino Acid Substitution; Animals; Asparagine; Conserved Sequence; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Kinetics; Lysine; Mutagenesis, Site-Directed; Recombinant Proteins; Vanadates | 2003 |
A new hemoglobin variant, Hb Fukui [alpha139(HC1)Lys --> Asn (AAA --> AAC) (alpha2)].
Topics: Asparagine; Base Sequence; DNA Primers; Genetic Variation; Hemoglobins, Abnormal; Humans; Japan; Lysine; Male; Middle Aged; Mutation, Missense | 2003 |
Possible founder effect of rapsyn N88K mutation and identification of novel rapsyn mutations in congenital myasthenic syndromes.
Topics: Adult; Amino Acid Substitution; Asparagine; Child; Child, Preschool; Female; Founder Effect; Humans; Infant; Lysine; Male; Muscle Proteins; Mutation; Myasthenic Syndromes, Congenital; Pedigree; Receptors, Nicotinic | 2003 |
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermedia
Topics: Adenosine Triphosphate; Animals; Asparagine; Calcium-Transporting ATPases; COS Cells; Enzyme Activation; Gene Deletion; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Lysine; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2003 |
A comparison of the mechanism for the reductive half-reaction between pea seedling and other copper amine oxidases (CAOs).
Topics: Amine Oxidase (Copper-Containing); Asparagine; Binding Sites; Copper; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Pisum sativum; Seeds | 2003 |
MHC recognition by hapten-specific HLA-A2-restricted CD8+ CTL.
Topics: Alanine; Amino Acid Substitution; Antigen Presentation; Asparagine; Cell Line; Cell Membrane; Cells, Cultured; Cytotoxicity, Immunologic; Dinitrobenzenes; Epitopes, T-Lymphocyte; Haptens; HLA-A Antigens; HLA-A2 Antigen; Humans; Lysine; Peptide Fragments; Protein Binding; T-Lymphocytes, Cytotoxic; Transfection | 2003 |
Focally folded myelin in Charcot-Marie-Tooth type 1B disease is associated with Asn131Lys mutation in myelin protein zero gene: short report.
Topics: Asparagine; Charcot-Marie-Tooth Disease; Child, Preschool; Female; Humans; Lysine; Male; Mutation; Myelin P0 Protein; Myelin Sheath; Pedigree | 2003 |
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Anions; Asparagine; Aspartic Acid; Binding Sites; Biological Transport; Cell Line; Cytoplasm; Drug Resistance; Estradiol; Humans; Hydrolysis; Kinetics; Leukotriene C4; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Synthesis Inhibitors; Protein Binding; Protein Structure, Tertiary; Rats; Serine; Time Factors; Transfection | 2003 |
Endothelin-1 gene Lys198Asn polymorphism and blood pressure reactivity.
Topics: Adolescent; Adult; Asparagine; Black People; Blood Pressure; Cold Temperature; Endothelin-1; Female; Forehead; Gene Frequency; Genotype; Hemodynamics; Heterozygote; Humans; Lysine; Male; Nitric Oxide; Obesity; Polymorphism, Genetic; Socioeconomic Factors; Stress, Physiological; Video Games; White People | 2003 |
Rearrangement of charge-charge interactions in variant ubiquitins as detected by double-mutant cycles and NMR.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Ubiquitin | 2003 |
Metabolic characterization of the genus Brucella. I. Statistical evaluation of the oxidative rates by which type I of each species can be identified.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Asparagine; Brucella; Brucella abortus; Brucella melitensis; Brucella suis; Brucellosis; Carbohydrate Metabolism; Galactose; Glutamic Acid; Lysine; Ornithine; Oxidation-Reduction; Ribose; Xylose | 1961 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
NUTRITIONAL CONTROL OF MORPHOGENESIS IN ARTHROBACTER CRYSTALLOPIETES.
Topics: Amino Acids; Arginine; Arthrobacter; Asparagine; Bacteriological Techniques; Butyrates; Colorimetry; Culture Media; Fumarates; Lactates; Lysine; Malates; Microscopy; Microscopy, Phase-Contrast; Morphogenesis; Phenylalanine; Research; Succinates | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
[STUDIES ON AMINO ACIDS REQUIRED FOR COLONY FORMATION OF SUBLETHALLY HEATED SPORES OF BACILLUS SUBTILIS].
Topics: Alanine; Amino Acids; Asparagine; Bacillus subtilis; Culture Media; Glutamates; Hot Temperature; Isoleucine; Lysine; Spores, Bacterial | 1964 |
COLORIMETRIC DIFFERENTIATION OF ALPHA- AND EPSILON-N-SUBSTITUTED LYSINE DERIVATIVES.
Topics: Aminocaproates; Aminocaproic Acid; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Colorimetry; Lysine; Ornithine; Research | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
NUTRITIONAL STUDIES OF DEVELOPMENT IN SCHIZOPHYLLIUM COMMUNE.
Topics: Acetates; Agaricales; Alcohols; Amino Acids; Ammonium Compounds; Asparagine; Carbohydrate Metabolism; Carbon; Carbon Dioxide; Citrates; Culture Media; Disaccharides; Glucose; Hot Temperature; Lysine; Metabolism; Nitrates; Nitrogen; Peptones; Pharmacology; Potassium; Quaternary Ammonium Compounds; Research; Succinates | 1964 |
RNA CODEWORDS AND PROTEIN SYNTHESIS, VI. ON THE NUCLEOTIDE SEQUENCES OF DEGENERATE CODEWORD SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE.
Topics: Asparagine; Base Sequence; Carbon Isotopes; Escherichia coli; Genetic Code; Isoleucine; Lysine; Nucleotides; Protein Biosynthesis; Proteins; Research; Ribosomes; RNA; Tyrosine | 1965 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen | 2003 |
Lack of founder haplotype for the rapsyn N88K mutation: N88K is an ancient founder mutation or arises from multiple founders.
Topics: Amino Acid Sequence; Animals; Asparagine; Child; Child, Preschool; Cohort Studies; Founder Effect; Haplotypes; Humans; Lysine; Male; Mice; Molecular Sequence Data; Muscle Proteins; Mutation, Missense; Physical Chromosome Mapping; Rats | 2004 |
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
Topics: Amino Acid Sequence; Animals; Arginine; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Dimerization; DNA Mutational Analysis; Enterovirus; Glutamic Acid; Hygromycin B; Kinetics; Lysine; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides, Antisense; Permeability; Protein Structure, Tertiary; RNA; Subcellular Fractions; Time Factors; Transfection; Tryptophan; Two-Hybrid System Techniques; Viral Nonstructural Proteins; Virus Replication | 2004 |
Function of conserved residues of human glutathione synthetase: implications for the ATP-grasp enzymes.
Topics: Adenosine Triphosphate; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Conserved Sequence; Crystallography, X-Ray; DNA; Glutamic Acid; Glutathione; Glutathione Synthase; Humans; Kinetics; Ligands; Lysine; Models, Chemical; Models, Molecular; Multigene Family; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Software | 2004 |
Proton uptake upon anaerobic reduction of the Paracoccus denitrificans cytochrome c oxidase: a kinetic investigation of the K354M and D124N mutants.
Topics: Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Calibration; Electron Transport Complex IV; Heme; Lysine; Methionine; Oxidation-Reduction; Paracoccus denitrificans; Phenolsulfonphthalein; Protein Subunits; Protons; Spectrophotometry | 2004 |
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Topics: Adult; Amino Acid Sequence; Animals; Antigen-Presenting Cells; Asparagine; B-Lymphocyte Subsets; Cathepsin G; Cathepsins; Cell Line; Cell Line, Transformed; Cell Separation; Cysteine Endopeptidases; Humans; Hydrolysis; Lymphocyte Activation; Lysine; Lysosomes; Mice; Molecular Sequence Data; Myelin Basic Protein; Phenylalanine; Protein Processing, Post-Translational; Serine; Serine Endopeptidases | 2004 |
Lysine metabolism is concurrently regulated by synthesis and catabolism in both reproductive and vegetative tissues.
Topics: Arabidopsis; Arabidopsis Proteins; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Cotyledon; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Germination; Hydro-Lyases; Lysine; Membrane Proteins; Methionine; Mutation; Plants, Genetically Modified; RNA Interference; Seeds | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation.
Topics: Asparagine; Bacillus Phages; Binding Sites; Capsid; Capsid Proteins; Cryoelectron Microscopy; Lysine; Protein Conformation; Protein Structure, Quaternary; Protein Subunits | 2004 |
Evaluation of the Lys198Asn and -134delA genetic polymorphisms of the endothelin-1 gene.
Topics: 5' Untranslated Regions; Adenine; Aged; Amino Acid Substitution; Animals; Asparagine; Cells, Cultured; COS Cells; Culture Media; Endothelin-1; Female; Gene Deletion; Gene Expression; Humans; Hypertension; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide | 2004 |
Methionine sustituted polyamides are RNAse mimics that inhibit translation.
Topics: Aminoglycosides; Animals; Asparagine; Imidazoles; In Vitro Techniques; Luciferases, Firefly; Lysine; Methionine; Molecular Mimicry; Nylons; Protein Biosynthesis; Protein Synthesis Inhibitors; Rabbits; Reticulocytes; Ribonucleases; RNA; Structure-Activity Relationship; Tryptophan | 2004 |
Identification of CC chemokine receptor 7 residues important for receptor activation.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Chemokine CCL19; Chemokine CCL21; Chemokines, CC; Chemotaxis; CHO Cells; COS Cells; Cricetinae; Dose-Response Relationship, Drug; Electroporation; Glutamine; Guanine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inhibitory Concentration 50; Jurkat Cells; Ligands; Lysine; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, CCR7; Receptors, Chemokine; Sequence Homology, Amino Acid; Time Factors; Transfection; Tyrosine | 2004 |
The congenital myasthenic syndrome mutation RAPSN N88K derives from an ancient Indo-European founder.
Topics: Asparagine; Europe; Evolution, Molecular; Founder Effect; Humans; India; Lysine; Muscle Proteins; Mutation, Missense; Myasthenic Syndromes, Congenital | 2004 |
Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Catalytic Domain; Chickens; Cross-Linking Reagents; Crystallography, X-Ray; DNA; DNA Methylation; Fungal Proteins; Gene Silencing; Glutamine; Histone-Lysine N-Methyltransferase; Histones; Hydrogen-Ion Concentration; Lysine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Nucleosomes; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Ultraviolet Rays | 2004 |
Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation.
Topics: Asparagine; Cell Line; Codon; Gene Expression Regulation; Genetic Variation; Humans; Isoleucine; Lysine; Mutation; Receptor, Melanocortin, Type 3; Receptors, G-Protein-Coupled; Receptors, LH; Threonine; Valine | 2004 |
Haplotype-phenotype correlations in kindreds with the N279K mutation in the tau gene.
Topics: Adult; Asparagine; Female; Haplotypes; Humans; Lysine; Male; Mutation; Phenotype; tau Proteins | 2004 |
K103N mutation in antiretroviral therapy-naive African patients infected with HIV type 1.
Topics: Amino Acid Substitution; Antiretroviral Therapy, Highly Active; Asparagine; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lysine; Male; Middle Aged; Mutation, Missense; RNA-Directed DNA Polymerase; Viral Proteins | 2004 |
Human LAT1 single nucleotide polymorphism N230K does not alter phenylalanine transport.
Topics: Animals; Anura; Asparagine; Biological Transport; Brain; Capillaries; Humans; Large Neutral Amino Acid-Transporter 1; Lysine; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Polymorphism, Single Nucleotide; Rabbits | 2004 |
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
Topics: Alanine; Amidohydrolases; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Gram-Negative Bacteria; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lysine; Mutagenesis, Site-Directed; Substrate Specificity; Zinc | 2005 |
[Angiotensin converting enzyme, NO-synthase, and endothelin-1 genes and left ventricular hypertrophy in natives of Yakutia with hypertensive disease].
Topics: Adult; Alanine; Asparagine; Blood Flow Velocity; Endothelin-1; Female; Gene Frequency; Genotype; Glycine; Humans; Hypertension; Hypertrophy, Left Ventricular; Lysine; Male; Middle Aged; Mitral Valve; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Russia; Severity of Illness Index | 2005 |
Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.
Topics: Alcohol Oxidoreductases; Asparagine; Bayes Theorem; Catalysis; Circular Dichroism; Cloning, Molecular; Crystallography, X-Ray; Haemophilus influenzae; Herbicides; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Models, Molecular; Mutagenesis; Mutagenesis, Site-Directed; NAD; NADP; Oxygen; Phylogeny; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Temperature | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
15N/14N position-specific isotopic analyses of polynitrogenous amino acids.
Topics: Amino Acids; Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Lysine; Nitrogen Isotopes; Reproducibility of Results | 2005 |
Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alanine; Asparagine; Aspartic Acid; Catalysis; Cold Temperature; Escherichia coli Proteins; Flavin-Adenine Dinucleotide; Folic Acid; Imines; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry; Substrate Specificity; Thermodynamics | 2005 |
Cooperativity and pseudo-cooperativity in the glutathione S-transferase from Plasmodium falciparum.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Asparagine; Binding Sites; Catalysis; Dimerization; Enzyme Inhibitors; Evolution, Molecular; Glutathione Transferase; Hemin; Inhibitory Concentration 50; Kinetics; Lysine; Models, Chemical; Models, Molecular; Nitrogen; Phosphates; Plasmodium falciparum; Potassium Compounds; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Static Electricity; Sulfhydryl Compounds | 2005 |
STI 571 inhibition effect on KITAsn822Lys-mediated signal transduction cascade.
Topics: Antineoplastic Agents; Asparagine; Benzamides; Cell Line, Tumor; Humans; Imatinib Mesylate; Lysine; Mutation; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Signal Transduction | 2005 |
Lys418Asn polymorphism of the alpha2-adrenoceptor gene relates to serum uric acid levels but not to insulin sensitivity.
Topics: Adult; Alleles; Asparagine; Gene Frequency; Genotype; Glycine; Homeostasis; Humans; Hyperuricemia; Insulin Resistance; Lysine; Male; Middle Aged; Norepinephrine; Polymorphism, Genetic; Predictive Value of Tests; Prevalence; Receptors, Adrenergic, alpha-2; Time Factors; Uric Acid; Waist-Hip Ratio | 2005 |
Lennard-Jones parameters for the combined QM/MM method using the B3LYP/6-31G*/AMBER potential.
Topics: Acetamides; Amino Acids; Asparagine; Aspartic Acid; Computer Simulation; Histidine; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Structure; Proteins; Serine; Thermodynamics | 2005 |
Difference FTIR studies reveal nitrogen-containing amino acid side chains are involved in the allosteric regulation of RecA.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Amino Acids; Arginine; Asparagine; Binding Sites; DNA-Binding Proteins; Escherichia coli Proteins; Glutamine; Hydrolysis; Lysine; Nitrogen; Nitrogen Isotopes; Protein Binding; Protein Conformation; Rec A Recombinases; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2005 |
The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level.
Topics: Apoptosis; Asparagine; Benzoquinones; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia, Myeloid, Acute; Lysine; Mutation; Proto-Oncogene Proteins c-kit; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 2006 |
Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation.
Topics: Alzheimer Disease; Animals; Asparagine; Avoidance Learning; Chromosomes, Human, Pair 17; Cognition Disorders; Disease Models, Animal; Hippocampus; Humans; Lysine; Maze Learning; Mice; Mice, Transgenic; Mutation, Missense; Nerve Tissue Proteins; Neurofibrillary Tangles; Phosphorylation; tau Proteins | 2005 |
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
Topics: Adenocarcinoma; Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Xeroderma Pigmentosum Group D Protein | 2007 |
Functional characterization of fibrinogen Bicêtre II: a gamma 308 Asn-->Lys mutation located near the fibrin D:D interaction sites.
Topics: Adult; Asparagine; Blood Coagulation; Coagulation Protein Disorders; Factor XIII; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogens, Abnormal; Fibrinolysis; Humans; Lysine; Male; Microscopy, Electron, Scanning; Models, Molecular; Mutation, Missense; Reference Values | 2006 |
Brain acetylcholinesterase activity in FTDP-17 studied by PET.
Topics: Acetylcholinesterase; Asparagine; Brain; Chromosomes, Human, Pair 17; Dementia; Frontal Lobe; Humans; Lysine; Male; Microtubule-Associated Proteins; Middle Aged; Mutation; Parkinsonian Disorders; Positron-Emission Tomography; tau Proteins; Temporal Lobe | 2006 |
The metal-binding sites of the zinc-transporting P-type ATPase of Escherichia coli. Lys693 and Asp714 in the seventh and eighth transmembrane segments of ZntA contribute to the coupling of metal binding and ATPase activity.
Topics: Adenosine Triphosphatases; Asparagine; Binding Sites; Copper; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Lysine; Metals; Phosphorylation; Protein Structure, Tertiary; Substrate Specificity; Zinc | 2006 |
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; Cisplatin; Cysteine; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Female; Gene Frequency; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
Leptin receptor Lys656Asn polymorphism is associated with decreased leptin response and weight loss secondary to a lifestyle modification in obese patients.
Topics: Adult; Asparagine; Body Mass Index; Exercise; Female; Humans; Leptin; Life Style; Lysine; Male; Middle Aged; Obesity; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Leptin; Weight Loss | 2006 |
Amino acid residues in the P2X7 receptor that mediate differential sensitivity to ATP and BzATP.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Conserved Sequence; Humans; Kinetics; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Sequence Homology, Amino Acid; Transfection | 2007 |
Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene.
Topics: Acyltransferases; Adult; Asparagine; Charcot-Marie-Tooth Disease; Cytosine; Foot Ulcer; Genetic Variation; Guanine; Heterozygote; Humans; Lysine; Male; Mutation, Missense; Pedigree; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Serine C-Palmitoyltransferase | 2006 |
Clinical-pathologic study of biomarkers in FTDP-17 (PPND family with N279K tau mutation).
Topics: Adult; Asparagine; Cerebral Cortex; Chromosomes, Human, Pair 17; Dementia; Family Health; Female; Fluorodeoxyglucose F18; Humans; Lysine; Male; Middle Aged; Mutation; Neuropsychological Tests; Parkinsonian Disorders; Positron-Emission Tomography; tau Proteins | 2007 |
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
Topics: Amyotrophic Lateral Sclerosis; Asparagine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Lysine; Middle Aged; Mutation; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.
Topics: Alanine; Amino Acid Substitution; Arginine; Asparagine; Epidermal Growth Factor; Factor VIIa; Factor X; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Thromboplastin | 2007 |
Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.
Topics: Adult; Amino Acid Substitution; Arsenic; Asparagine; Aspartic Acid; Case-Control Studies; Female; Genetic Predisposition to Disease; Glutamine; Humans; Lysine; Male; Polymorphism, Single Nucleotide; Skin Diseases; Sunburn; Water Supply; Xeroderma Pigmentosum Group D Protein | 2007 |
Mutagenesis of lysine 62, asparagine 64, and conserved region 1 reduces the activity of human ecto-ATPase (NTPDase 2).
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Cations, Divalent; Conserved Sequence; Enzyme Activation; Enzyme Inhibitors; Glycosylation; Humans; Lysine; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2007 |
Mass spectrometrical analysis of the processed metastasis-inducing anterior gradient protein 2 homolog reveals 100% sequence coverage.
Topics: Amino Acid Sequence; Asparagine; Biomarkers, Tumor; Chymotrypsin; Electrophoresis, Gel, Two-Dimensional; Humans; Lysine; Mass Spectrometry; Mucoproteins; Oncogene Proteins; Proteins; Sensitivity and Specificity; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Trypsin | 2008 |
FGFR3 mutations and medial temporal lobe dysgenesis.
Topics: Asparagine; Child, Preschool; Humans; Lysine; Magnetic Resonance Imaging; Male; Mutation; Osteochondrodysplasias; Receptor, Fibroblast Growth Factor, Type 3; Temporal Lobe | 2007 |
A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization.
Topics: Amino Acid Motifs; Aquaporin 1; Asparagine; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Folding | 2007 |
The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model.
Topics: Age Factors; Analysis of Variance; Animals; Asparagine; Behavior, Animal; Central Nervous System; Chromosomes, Human, Pair 17; Dementia; Embryo, Mammalian; Exons; Gene Expression Regulation, Developmental; Humans; Lysine; Maze Learning; Mice; Mice, Transgenic; Models, Molecular; Motor Activity; Nerve Tissue Proteins; Neurons; Parkinsonian Disorders; RNA Splicing; tau Proteins | 2007 |
Variable phenotypic manifestations of a K44N mutation in the TGIF gene.
Topics: Asparagine; Child; DNA Mutational Analysis; Holoprosencephaly; Homeodomain Proteins; Humans; Lysine; Male; Mutation; Repressor Proteins | 2008 |
Effect of amino acids and antibodies against nerve growth factor receptors on the development of organotypic culture of lymphoid tissue.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Asparagine; Cell Proliferation; Glutamic Acid; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Nerve Growth Factor; Spleen | 2007 |
Structural basis for catalysis by onconase.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Disulfides; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; K562 Cells; Kinetics; Lysine; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Ribonucleases; Sequence Homology, Amino Acid; Substrate Specificity; X-Ray Diffraction | 2008 |
Stabilizing isopeptide bonds revealed in gram-positive bacterial pilus structure.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Fimbriae Proteins; Fimbriae, Bacterial; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Sequence Data; Peptides; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Streptococcus pyogenes | 2007 |
Interaction of the Lys(3614)-Asn(3643) calmodulin-binding domain with the Cys(4114)-Asn(4142) region of the type 1 ryanodine receptor is involved in the mechanism of Ca2+/agonist-induced channel activation.
Topics: Animals; Asparagine; Calcium; Calcium Channels; Calmodulin; Cysteine; Lysine; Molecular Weight; Protein Binding; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2008 |
Development of fructosyl amine oxidase specific to fructosyl valine by site-directed mutagenesis.
Topics: Amino Acid Oxidoreductases; Asparagine; Bacillus; Buffers; Glycated Hemoglobin; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Pichia; Recombinant Proteins; Sarcosine Oxidase; Substrate Specificity; Valine | 2008 |
Binding of ATP to UAP56 is necessary for mRNA export.
Topics: Adenosine Triphosphate; Antigens, Nuclear; Asparagine; Cytoplasm; DEAD-box RNA Helicases; Fluorescence Recovery After Photobleaching; HeLa Cells; Humans; Lysine; Mitosis; Mutant Proteins; Nuclear Matrix-Associated Proteins; Point Mutation; Protein Binding; RNA Splicing; RNA Transport; RNA-Binding Proteins; RNA, Messenger | 2008 |
[Plasmodium falciparum chloroquine and pyrimethamine resistance monitoring network with molecular tools in the Niger River valley, Republic of Niger].
Topics: Animals; Antigens, Protozoan; Antimalarials; Asparagine; Biomarkers; Chloroquine; Communicable Disease Control; Drug Resistance; Humans; Lysine; Membrane Transport Proteins; Mutation; Niger; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 2008 |
Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Asparagine; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Conserved Sequence; ErbB Receptors; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutation, Missense; Nuclear Proteins; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; RNA Interference | 2008 |
Influence of Lys656Asn polymorphism of leptin receptor gene on insulin resistance in patients with diabetes mellitus type 2.
Topics: Amino Acid Substitution; Asparagine; Body Mass Index; Cytokines; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lysine; Obesity; Polymorphism, Genetic; Receptors, Leptin | 2008 |
EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes.
Topics: Age of Onset; Aged; Asparagine; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelin-1; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Regression Analysis | 2008 |
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function.
Topics: Action Potentials; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Asparagine; Biophysical Phenomena; Cell Line; Ether-A-Go-Go Potassium Channels; Humans; Ion Channel Gating; Lysine; Mutant Proteins; Mutation; Temperature; Time Factors; Xenopus | 2008 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
Influence of preformed Asp23-Lys28 salt bridge on the conformational fluctuations of monomers and dimers of Abeta peptides with implications for rates of fibril formation.
Topics: Amyloid; Amyloid beta-Peptides; Asparagine; Computer Simulation; Dimerization; Lactams; Lysine; Models, Molecular; Peptide Fragments; Protein Conformation; Salts; Thermodynamics | 2009 |
Magnetic resonance imaging, magnetic resonance spectroscopy, and facial dysmorphism in a case of Lowe syndrome with novel OCRL1 gene mutation.
Topics: Asparagine; Brain; Child; DNA Mutational Analysis; Exons; Face; Humans; Lysine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mutation; Oculocerebrorenal Syndrome; Phosphoric Monoester Hydrolases | 2009 |
Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry.
Topics: Alanine; Amino Acid Sequence; Asparagine; Binding Sites; Crystallography, X-Ray; Fimbriae Proteins; Fimbriae, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Lysine; Mass Spectrometry; Models, Molecular; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary | 2009 |
Incorporating structural characteristics for identification of protein methylation sites.
Topics: Arginine; Asparagine; Binding Sites; Computer Simulation; Glutamic Acid; Lysine; Methylation; Protein Conformation; Proteins; Surface Properties | 2009 |
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.
Topics: Amino Acid Substitution; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Malates; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Nitro Compounds; Propionates; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine | 2009 |
Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions.
Topics: Afibrinogenemia; Asparagine; Crystallography, X-Ray; Fibrinogens, Abnormal; Hemorrhagic Disorders; Humans; Hydrogen Bonding; Lysine; Protein Interaction Mapping; Protein Stability; Protein Structure, Tertiary | 2009 |
The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Corynebacterium diphtheriae; Crystallography, X-Ray; Disulfides; Fimbriae Proteins; Immunoglobulins; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Threonine | 2009 |
Contributions of active site residues to cofactor binding and catalysis of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.
Topics: Androsterone; Asparagine; Catalysis; Catalytic Domain; Fluorescence Polarization; Hydroxysteroid Dehydrogenases; Kinetics; Lysine; Mutation; NAD; Protein Binding; Tyrosine | 2010 |
Biochemical analysis of phenotypic diversity associated with mutations in codon 244 of the retinal degeneration slow gene.
Topics: Amino Acid Substitution; Animals; Asparagine; Chlorocebus aethiops; Codon; COS Cells; Eye Proteins; Genetic Variation; Histidine; Intermediate Filament Proteins; Lysine; Membrane Glycoproteins; Membrane Proteins; Mice; Nerve Tissue Proteins; Peripherins; Phenotype; Retinal Degeneration; Tetraspanins | 2010 |
Mechanism for the selective interaction of C-terminal Eps15 homology domain proteins with specific Asn-Pro-Phe-containing partners.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Asparagine; Calcium-Binding Proteins; Glutathione Transferase; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Phenylalanine; Phosphoproteins; Proline; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Two-Hybrid System Techniques | 2010 |
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation.
Topics: Amino Acid Substitution; Asparagine; Benzimidazoles; Cell Line; Cell Survival; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mutant Proteins; Mutation, Missense; Protein Binding; Reverse Transcriptase Inhibitors | 2010 |
A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cell Line; Female; Genes, Recessive; Genetic Testing; Humans; Lysine; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Neuropilin-1; Point Mutation; Protein Binding; Semaphorin-3A; Signal Transduction | 2010 |
Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam.
Topics: Animals; Asparagine; Cluster Analysis; Disease Models, Animal; Genotype; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Orthomyxoviridae Infections; Phylogeny; RNA-Dependent RNA Polymerase; RNA, Viral; Sequence Analysis, DNA; Sequence Homology; Vietnam; Viral Proteins; Virulence; Virulence Factors | 2010 |
A case of carotid body paraganglioma and haemangioblastoma of the spinal cord in a patient with the N131K missense mutation in the VHL gene.
Topics: Asparagine; Carotid Body Tumor; Female; Hemangioblastoma; Humans; Lysine; Middle Aged; Mutation, Missense; Spinal Cord Neoplasms; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein | 2011 |
Molecular analysis of connexin26 asparagine14 mutations associated with syndromic skin phenotypes.
Topics: Adult; Asparagine; Aspartic Acid; Cell Membrane; Child; Connexin 26; Connexins; Cytoplasm; Endoplasmic Reticulum; Female; Fluoresceins; Gap Junctions; Hearing Loss; HeLa Cells; Humans; Hypertrichosis; Keratoderma, Palmoplantar; Keratosis; Lysine; Male; Mutation, Missense; Nails, Malformed; Protein Transport; Skin; Skin Diseases; Syndrome; Transfection; Tyrosine | 2011 |
Visual grasping in frontotemporal dementia and parkinsonism linked to chromosome 17 (microtubule-associated with protein tau): a comparison of N-Isopropyl-p-[(123)I]-iodoamphetamine brain perfusion single photon emission computed tomography analysis with
Topics: Adult; Aged; Asparagine; Benzamides; Brain; Chromosomes, Human, Pair 17; Female; Hand Strength; Humans; Lysine; Male; Middle Aged; Parkinsonian Disorders; Pyrrolidines; Supranuclear Palsy, Progressive; tau Proteins; Tomography, Emission-Computed, Single-Photon | 2011 |
Anatomy of disturbed sleep in pallido-ponto-nigral degeneration.
Topics: Actigraphy; Adult; Asparagine; Female; Genetic Testing; Globus Pallidus; Humans; Lysine; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Neurofibrillary Tangles; Polysomnography; Pons; Severity of Illness Index; Sleep Wake Disorders; Substantia Nigra; tau Proteins; Tyrosine 3-Monooxygenase; Young Adult | 2011 |
Effects of mutations of Lys41 and Asp102 of bacteriorhodopsin.
Topics: Amino Acid Sequence; Asparagine; Bacteriorhodopsins; Halobacterium salinarum; Hydrogen-Ion Concentration; Kinetics; Light; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Proton Pumps; Retinaldehyde | 2011 |
Engineering of a metagenome derived lipase toward thermal tolerance: effect of asparagine to lysine mutation on the protein surface.
Topics: Amino Acid Substitution; Animals; Asparagine; Circular Dichroism; Enzyme Stability; Lipase; Lysine; Metagenome; Protein Conformation; Protein Folding; Temperature | 2012 |
The kinase activity of the Helicobacter pylori Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase is sensitive to distal mutations in its putative ammonia tunnel.
Topics: Ammonia; Asparagine; Aspartate-tRNA Ligase; Enzyme Activation; Glutamine; Helicobacter pylori; Lysine; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrogenous Group Transferases; Phosphorylation; RNA, Transfer, Amino Acyl; Staphylococcus aureus; Tyrosine | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution.
Topics: Amino Acid Motifs; Amino Acid Sequence; Archaeoglobus fulgidus; Asparagine; Catalytic Domain; Crystallography, X-Ray; Hexosyltransferases; Lysine; Membrane Proteins; Molecular Sequence Data; Mutation; Protein Conformation; Pyrococcus | 2012 |
The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene.
Topics: Acoustic Stimulation; Age Factors; Alcohol Oxidoreductases; Animals; Animals, Newborn; Asparagine; Barium; Biophysical Phenomena; Cadherins; Cell Line, Transformed; Cochlea; Disease Models, Animal; DNA-Binding Proteins; Evoked Potentials, Auditory, Brain Stem; Green Fluorescent Proteins; Hair Cells, Auditory; Humans; Lysine; Mechanoreceptors; Membrane Potentials; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Scanning; Mutation; Nerve Fibers; Organ Culture Techniques; Patch-Clamp Techniques; Physical Stimulation; Psychoacoustics; Pyridinium Compounds; Quaternary Ammonium Compounds; Receptors, AMPA; Synapses; Transfection; Usher Syndromes | 2012 |
Is etravirine and two nucleosides an option for HIV with an isolated K103N mutation?
Topics: Adenine; Adult; Anti-HIV Agents; Asparagine; Deoxycytidine; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; HIV Seropositivity; HIV-1; Humans; Lysine; Male; Mutation; Nitriles; Organophosphonates; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Tenofovir | 2013 |
A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site.
Topics: Amino Acid Motifs; Amino Acyl-tRNA Synthetases; Aminoacylation; Asparagine; Catalytic Domain; Crystallography, X-Ray; Hydrogen Bonding; Lysine; Methanosarcina; Protein Binding; Protein Conformation; Protein Multimerization; Substrate Specificity | 2013 |
A C-terminal di-leucine motif controls plasma membrane expression of PMCA4b.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Calcium; Cell Compartmentation; Cell Count; Cell Membrane; Dogs; Dynamins; Endocytosis; Endosomes; Green Fluorescent Proteins; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Isoenzymes; Leucine; Lysine; Madin Darby Canine Kidney Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasma Membrane Calcium-Transporting ATPases; Protein Sorting Signals; Protein Transport; Sequence Alignment; Structure-Activity Relationship; Subcellular Fractions | 2013 |
Enhanced silencing and stabilization of siRNA polyplexes by histidine-mediated hydrogen bonds.
Topics: Asparagine; Cell Line, Tumor; Gene Silencing; Histidine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Peptides; Polylysine; Polymers; Protein Conformation; RNA, Small Interfering; Transfection | 2014 |
Comparative analysis of barophily-related amino acid content in protein domains of Pyrococcus abyssi and Pyrococcus furiosus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Evolution, Molecular; Genome, Archaeal; Lysine; Protein Structure, Tertiary; Proteome; Pyrococcus abyssi; Pyrococcus furiosus; Threonine | 2013 |
Synergistic effect of LEP and LEPR gene polymorphism on body mass index in a Chinese population.
Topics: Adult; Alleles; Arginine; Asian People; Asparagine; Body Mass Index; China; Female; Genetic Predisposition to Disease; Genotype; Humans; Leptin; Logistic Models; Lysine; Male; Obesity; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Prevalence; Receptors, Leptin; Risk Factors; Waist-Hip Ratio | 2013 |
A model of glycosylated human butyrylcholinesterase.
Topics: Asparagine; Butyrylcholinesterase; Catalytic Domain; Cocaine; Glycosylation; Half-Life; Humans; Lysine; Models, Molecular; Molecular Dynamics Simulation; Polyethylene Glycols; Polysaccharides; Protein Stability; Protein Structure, Tertiary | 2014 |
Amino acid derivatives as bitter taste receptor (T2R) blockers.
Topics: Alanine; Amino Acids; Asparagine; Binding Sites; GABA Agents; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Lysine; Models, Molecular; Molecular Structure; Mutation; Protein Binding; Protein Structure, Tertiary; Quinine; Receptors, G-Protein-Coupled; Taste; Threonine | 2014 |
In silico investigation of potential pyruvate kinase M2 regulators from traditional Chinese medicine against cancers.
Topics: Asparagine; Binding Sites; Carrier Proteins; Chemistry, Pharmaceutical; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Ligands; Lysine; Medicine, Chinese Traditional; Membrane Proteins; Mitosis; Molecular Dynamics Simulation; Neoplasms; Protein Conformation; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tryptophan | 2014 |
Investigation of the reactions of acrylamide during in vitro multistep enzymatic digestion of thermally processed foods.
Topics: Acrylamide; Asparagine; Bread; Carcinogens; Cooking; Cystine; Dietary Carbohydrates; Digestion; Food Contamination; Gastric Juice; Hot Temperature; Humans; Intestinal Secretions; Lysine; Models, Molecular; Molecular Structure; Plant Roots; Schiff Bases; Solanum tuberosum | 2015 |
β-Lactoglobulin mutant Lys69Asn has attenuated IgE and increased retinol binding activity.
Topics: Antibodies, Monoclonal; Asparagine; Humans; Immunoglobulin E; Immunoglobulin G; Lactoglobulins; Lysine; Milk Hypersensitivity; Mutation; Palmitic Acid; Pichia; Protein Binding; Resveratrol; Stilbenes; Vitamin A | 2015 |
Mechanism of hydrogen activation by [NiFe] hydrogenases.
Topics: Alanine; Amino Acid Substitution; Asparagine; Crystallography, X-Ray; Escherichia coli Proteins; Guanidine; Hydrogen; Hydrogenase; Iron; Lysine; Mutation; Nickel; Protein Conformation | 2016 |
Salt bridge as a gatekeeper against partial unfolding.
Topics: Asparagine; Circular Dichroism; Escherichia coli; Escherichia coli Proteins; Lysine; Models, Molecular; Mutation; Protein Stability; Protein Structure, Secondary; Protein Unfolding; Proteolysis; Ribonuclease H; Salts; Thermodynamics | 2016 |
Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Asparagine; Aurora Kinase B; Cell Cycle; Cell Cycle Proteins; Centromere; Cyclin B; Glutamic Acid; Kinetochores; Lysine; Nuclear Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus | 2017 |
Engineering a Lys-Asn isopeptide bond into an immunoglobulin-like protein domain enhances its stability.
Topics: Asparagine; Bacterial Proteins; Immunoglobulins; Lysine; Mutagenesis; Protein Domains; Protein Engineering; Protein Stability; Streptococcus pyogenes | 2017 |
Asn194Lys mutation in RVG29 peptide increases GFP transgene delivery by endocytosis to neuroblastoma and astrocyte cells.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Asparagine; Astrocytes; Cells, Cultured; Endocytosis; Gene Transfer Techniques; Glycoproteins; Green Fluorescent Proteins; Lysine; Mice; Mutation; Neuroblastoma; Peptide Fragments; Transgenes; Viral Proteins | 2017 |
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria.
Topics: Animals; Asparagine; Genetic Code; Hydroxylation; Lysine; Mitochondria; RNA Processing, Post-Transcriptional; RNA, Transfer, Lys; Sea Urchins | 2017 |
Stereoselective Deuteration in Aspartate, Asparagine, Lysine, and Methionine Amino Acid Residues Using Fumarate as a Carbon Source for Escherichia coli in D
Topics: Amino Acids; Asparagine; Aspartic Acid; Carbon; Culture Media; Deuterium; Escherichia coli; Fumarates; Humans; Lysine; Methionine; Models, Molecular; Mutant Proteins; NIMA-Interacting Peptidylprolyl Isomerase; Stereoisomerism | 2017 |
Modification of chitosan-bead support materials with L-lysine and L-asparagine for α-amylase immobilization.
Topics: alpha-Amylases; Asparagine; Chitosan; Enzymes, Immobilized; Hydrogen-Ion Concentration; Lysine | 2018 |
Activity of Topotecan toward the DNA/Topoisomerase I Complex: A Theoretical Rationalization.
Topics: Asparagine; DNA; DNA Topoisomerases, Type I; Humans; Lysine; Molecular Dynamics Simulation; Quantum Theory; Structure-Activity Relationship; Thermodynamics; Topoisomerase I Inhibitors; Topotecan | 2018 |
Novel Lys215Asn mutation in an Italian family with Thomsen myotonia.
Topics: Adult; Asparagine; Chloride Channels; DNA Mutational Analysis; Electromyography; Family Health; Humans; Italy; Lysine; Male; Middle Aged; Mutation; Myotonia Congenita | 2018 |
A novel D90_K91insN mutation in exon 4 of the SOD1 gene caused familial amyotrophic lateral sclerosis in a Chinese pedigree.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Asparagine; Computational Biology; DNA Mutational Analysis; Exons; Humans; Lysine; Male; Middle Aged; Models, Molecular; Mutation; Pediatrics; Superoxide Dismutase-1 | 2018 |
Bilirubin Interference in Plasma Amino Acid Analysis by Ion Exchange Chromatography.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Bilirubin; Cellulose; Child, Preschool; Chromatography, Ion Exchange; Cross-Sectional Studies; Cystine; Female; Glycine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Tryptophan | 2018 |
Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S-transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis.
Topics: Aged; Asparagine; Aspartic Acid; Cell Survival; Disease-Free Survival; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Glutathione Transferase; Humans; Lysine; Melanoma; Middle Aged; Prognosis; Proportional Hazards Models; Skin Neoplasms; Treatment Outcome; Xeroderma Pigmentosum | 2019 |
Identification of Lysine Misincorporation at Asparagine Position in Recombinant Insulin Analogs Produced in E. coli.
Topics: Asparagine; Chromatography, High Pressure Liquid; Escherichia coli; Humans; Insulins; Lysine; Peptides; Recombinant Proteins; Tandem Mass Spectrometry | 2019 |
HLA-A*31:68, a novel variant of HLA-A*31, discovered in a Taiwanese individual.
Topics: Amino Acid Substitution; Asian People; Asparagine; Base Sequence; Blood Donors; Histocompatibility Testing; HLA-A Antigens; Humans; Lysine; Mutation, Missense; Sequence Analysis, DNA; Taiwan | 2019 |
Delineating elastic properties of kinesin linker and their sensitivity to point mutations.
Topics: Alanine; Amino Acid Sequence; Asparagine; Computer Simulation; Elasticity; Kinesins; Lysine; Molecular Dynamics Simulation; Molecular Motor Proteins; Point Mutation; Protein Conformation; Protein Domains | 2020 |
Simultaneous generation of acrylamide, β-carboline heterocyclic amines and advanced glycation ends products in an aqueous Maillard reaction model system.
Topics: Acrylamide; Amines; Asparagine; Carbolines; Chromatography, Gas; Chromatography, High Pressure Liquid; Glucose; Glycation End Products, Advanced; Harmine; Hot Temperature; Lysine; Maillard Reaction; Models, Biological; Pyruvaldehyde | 2020 |
Asparagine and Glutamine Residues Participate in Protein Covalent Binding by Epoxide Metabolite of 8-Epidiosbulbin E Acetate
Topics: Amides; Amines; Animals; Asparagine; Cytochrome P-450 CYP3A; Diterpenes; Epoxy Compounds; Glutamine; Lysine; Mice | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility.
Topics: Asparagine; COVID-19; Endothelial Cells; Humans; Lysine; Mutation; Pandemics; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2022 |
Metabolomic profiling in kidney cells treated with a sodium glucose-cotransporter 2 inhibitor.
Topics: Arginine; Asparagine; Epithelial Cells; Glucose; Glutathione; Histidine; Humans; Isoleucine; Kidney; Lysine; Metabolomics; Methionine; Phenylalanine; Proline; Sodium; Sodium-Glucose Transporter 2; Threonine | 2023 |
Influence of Deamidation on the Formation of Pyrazines and Proline-Specific Compounds in Maillard Reaction of Asparagine and Proline with Glucose.
Topics: Asparagine; Glucose; Lysine; Maillard Reaction; Proline; Pyrazines | 2023 |
Lipid Peroxidation Products Influence Calpain-1 Functionality In Vitro by Covalent Binding.
Topics: Aldehydes; Asparagine; Calpain; Chromatography, Liquid; Glutamine; Hexobarbital; Histidine; Lipid Peroxidation; Lysine; Tandem Mass Spectrometry | 2023 |
Study on the non-enzymatic browning of lotus rhizome juice during sterilization mediated by 1,2-dicarboxyl and heterocyclic compounds.
Topics: Asparagine; Fructose; Glucose; Glutamine; Glyoxal; Heterocyclic Compounds; Lotus; Lysine; Maillard Reaction; Pyruvaldehyde; Rhizome; Sterilization | 2024 |
L-Lysine supplementation affects dietary protein quality and growth and serum amino acid concentrations in rats.
Topics: Amino Acids; Animals; Asparagine; Carnitine; Caseins; Diet; Dietary Proteins; Dietary Supplements; Histidine; Leucine; Lysine; Male; Methionine; Ornithine; Racemethionine; Rats; Rats, Sprague-Dawley; Tryptophan; Valine; Weight Gain | 2023 |