asparagine has been researched along with leucine in 225 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 118 (52.44) | 18.7374 |
| 1990's | 33 (14.67) | 18.2507 |
| 2000's | 52 (23.11) | 29.6817 |
| 2010's | 14 (6.22) | 24.3611 |
| 2020's | 8 (3.56) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Barash, I; Breiman, A | 1 |
| Charache, S; Fox, J; Hathaway, P; Jessop, M; Kazazian, H; McCurdy, P; van Beneden, R; Winslow, R | 1 |
| Andrulis, IL; Arfin, SM; Hatfield, GW | 1 |
| Agranoff, BW; Heacock, AM | 1 |
| Hosbach, HA; Kubli, E | 1 |
| Lee, SG; Lipmann, F | 1 |
| Denham, DA; Hebert, CN; Lesslie, IW | 1 |
| Netrval, J | 1 |
| Chang, WC; Li, CH; Tseng, LF; Yamashiro, D | 1 |
| Allin, EP; Guetard, D | 1 |
| Gutte, B | 1 |
| Bürger, U; Wolf, H | 1 |
| Rognstad, R | 1 |
| Nakayama, T; Narita, K | 1 |
| Jayme, DW; Moore, PA; Oxender, DL | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Chellemi, F | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Siminovitch, L; Stanners, CP; Thompson, LH | 1 |
| Blouquit, Y; Cottenceau, D; Galacteros, F; Kister, J; Trastour, JC; Vasseur, C; Wajcman, H | 1 |
| McAlister-Henn, L; Steffan, JS | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Eijsink, VG; van den Burg, B; van der Zee, JR; Venema, G; Vriend, G | 1 |
| Spiro, MJ; Spiro, RG | 1 |
| Imoto, T; Ueda, T; Yamada, H | 1 |
| Mircevová, L; Mokrý, Z; Simonová, A | 1 |
| McClure, WO; Schlichter, DJ | 1 |
| Pliskowá, M | 1 |
| Hirschhorn, K; Waithe, WI; Weiner, MS | 1 |
| Dikow, A; Lolova, I | 1 |
| Miyazawa, Y; Sekine, T; Yamaguchi, M | 1 |
| Nair, PM; Sreenivasan, A | 1 |
| Park, WK; Regoli, D; Rioux, F | 1 |
| Caputo, A; Carrara, G; Castelli, L; Cioé, L; Perez-Bercoff, R; Rita, G | 1 |
| McConnell, HM; Ogata, RT | 1 |
| Hogan, BL; Murden, S | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Iijima, T; Sato, T | 1 |
| Melera, PW; Momeni, C; Rusch, HP | 1 |
| Batra, KV; Dolowy, WC; Holcenberg, JS; Roberts, J; Schrek, R | 1 |
| Peterkofsky, A; Powers, DM | 1 |
| Camerer, W; Galanos, C; Rietschel, ET; Rietschel, M | 1 |
| Halpern, YS | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Cline, TR; Crosby, LO | 1 |
| Nair, PM; Shirsat, SG | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Kalnitsky, G; Spadari, S; Subramanian, AR | 1 |
| Broome, JD | 2 |
| Koehn, PV; Perlmann, GE | 1 |
| Berger, H; Yanofsky, C | 1 |
| Balis, ME; Miller, HK | 1 |
| Dolowy, WC; Holcenberg, JS; Roberts, J | 1 |
| Gross, R; Hirschmann, WD; Oerkermann, H | 1 |
| Kaneda, T | 1 |
| Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
| Buu-Hoï, NP; Hauspie, R; Lambelin, G; Nicolle, J | 1 |
| Belasco, IJ | 1 |
| Nair, PM | 1 |
| Gross, W; Ring, K | 1 |
| Brinster, RL | 1 |
| Svábová-Stronová, M | 1 |
| Andrews, AT; Bates, CJ; Chang, PK; Fischer, GA; Handschumacher, RE | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Graeber, W | 1 |
| Jones, OW; Nirenberg, MW | 1 |
| Schubert, RH | 1 |
| Nicholson, I | 1 |
| Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
| Balian, G; Bornstein, P | 1 |
| Imada, M; Inouye, M; Tsugita, A | 1 |
| Wilke, J | 1 |
| Gevers, W; Kleinkauf, H; Lipmann, F; Roskoski, R | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Agranoff, BW; Elam, JS | 1 |
| Voris, L | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Thiry, L | 1 |
| Gordon, CS; Mashburn, LT | 1 |
| Cahill, CL; Li, SC | 1 |
| Schneider, G | 1 |
| Dietel, K; Schmöger, R | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Jefferson, LS; Korner, A | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Chang, CC; Hayashi, K; Suzuki, T; Yang, CC | 1 |
| Bien, S; Chakrabarti, JK; Friedman, OM; Olsen, G; Scher, C; Sommer, HZ | 1 |
| Fleischmann, L; Santamaria, L | 1 |
| Hentschel, G; Kull, U | 1 |
| Grooten, HJ; van der Horst, CJ | 1 |
| Makarov, PV | 1 |
| Braams, R | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Broome, JD; Schwartz, JH | 1 |
| Grinde, B; Seglen, PO | 3 |
| Abbracchio, MP; Costa, M; Meloni, M | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Hellerström, C; Herchuelz, A; Lebrun, P; Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Welsh, M | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Welsh, M | 1 |
| Kiyama, S; Makita, M; Watanabe, Y; Yamamoto, S | 1 |
| Manchester, KL; Tyobeka, EM | 1 |
| Hanson, DK; Maróti, P; Schiffer, M; Sebban, P | 1 |
| Vilsen, B | 1 |
| Offer, G; Sessions, R | 1 |
| Cornish, VW; Kaplan, MI; Kollman, PA; Schultz, PG; Veenstra, DL | 1 |
| Danielsson, O; Estonius, M; Höög, JO; Jörnvall, H | 1 |
| Brenner, B; Clemetson, JM; Clemetson, KJ; Kyrle, PA | 1 |
| Basilico, C; Gong, SS; Guerrini, L; Mangasarian, K | 1 |
| Codogno, P; Houri, JJ; Ogier-Denis, E; Trugnan, G | 1 |
| Iwasaki, M; Juvonen, RO; Lindberg, RL; Negishi, M | 1 |
| Atkinson, SJ; Butler, GS; Murphy, G; Smith, B; Will, H | 1 |
| Fink, AL; Lewis, ER; Winterberg, KM | 1 |
| Clausen, JO; Fridberg, M; Hansen, T; Møller, AM; Pedersen, O; Rasmussen, SK; Urhammer, SA | 1 |
| Delaney, JK; Subramaniam, S | 1 |
| Ellis, WR; Hill, CP; Martins, LJ | 1 |
| Chan, AM; Feuer, B; Lorenzi, MV; Saez, R; Tolkacheva, T | 1 |
| Bogumil, R; Brayer, GD; Luo, Y; Mauk, AG; Maurus, R; Overall, CM; Smith, M | 1 |
| de la Morena, ML; Hendrixson, DR; St Geme, JW; Stathopoulos, C | 1 |
| Finazzi, G; Joliot, P; Wollman, FA; Zito, F | 1 |
| Guo, J; Ko, DC; Marr, MT; Roberts, JW | 1 |
| Clausen, JO; Eiberg, H; Ekstrøm, CT; Hansen, T; Møller, AM; Nyholm, B; Pedersen, O; Schmitz, O; Urhammer, SA | 1 |
| Dong, S; Hecht, MH; Spiro, TG; Ybe, JA | 1 |
| Cordes, MH; McKnight, CJ; Sauer, RT; Walsh, NP | 1 |
| Baardsnes, J; Chao, H; Davies, PL; Hodges, RS; Houston, ME; Kay, CM; Loewen, MC; Sönnichsen, FD; Sykes, BD | 1 |
| Benashski, SE; King, SM; Maciejewski, MW; Mullen, GP; Wu, H | 1 |
| Abbenante, G; Alewood, D; Alewood, PF; Begun, J; Bergman, DA; Brinkworth, RI; Fairlie, DP; March, DR; Martin, JL; Reid, RC; Schindeler, A; Wickramasinghe, WA | 1 |
| French, GL; Shannon, KP; Stapleton, PD | 1 |
| Hendrich, MP; Ho, C; Ho, NT; Jeong, ST | 1 |
| Arora, KK; Catt, KJ; Chung, HO; Yang, Q | 1 |
| Beavil, AJ; Davison, E; Kirby, I; Kovesdi, I; Roelvink, PW; Santis, G; Soh, CP; Sutton, BJ; Wickham, TJ | 1 |
| Afshar-Kharghan, V; Dong, JF; Gineys, G; Li, CQ; López, JA; McIntire, LV; Schade, AJ; Sun, L | 1 |
| Alexov, E; Baciou, L; Gunner, MR; Hanson, DK; Miksovska, J; Schiffer, M; Sebban, P | 1 |
| Carrell, CJ; Cramer, WA; Ponamarev, MV; Sainz, G; Smith, JL; Soriano, GM | 1 |
| Cummings, D; Jesaitis, AJ; Miettinen, HM; Mills, JS | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Miyahara, I; Mizuguchi, H; Okada, K | 1 |
| Kimura, M; Numata, T; Suzuki, A; Tanaka, I; Yao, M | 1 |
| Harding, MM; Haymet, AD; Ward, LG | 1 |
| Mayer, MR; Stone, MJ | 1 |
| Battistuzzi, G; Borsari, M; De Rienzo, F; Loschi, L; Menziani, MC; Sola, M | 1 |
| Farazi, TA; Gordon, JI; Manchester, JK; Waksman, G | 1 |
| Dessen, A; Dideberg, O; Gordon, E; Hopkins, J; Mouz, N | 1 |
| Chin, HS; Sim, J; Sim, TS | 1 |
| Lario, PI; Sampson, NS; Vrielink, A; Yin, Y | 1 |
| Bergman, A; Brocchieri, L; Gentles, AJ; Karlin, S; Mrazek, J | 1 |
| Liang, J; Luba, J; McGee, MP | 1 |
| Antholine, W; Ferguson-Miller, S; Kang, UG; Schmidt, B; Zhen, Y | 1 |
| Durham, B; Ferguson-Miller, S; Geren, L; Ma, L; Millett, F; Wang, K; Zhen, Y | 1 |
| Ermolenko, DN; Loladze, VV; Makhatadze, GI | 1 |
| Findlay, JB; Nevett, CL; Wrigley, JD | 1 |
| Björk, I; Pavlova, A | 1 |
| Acharya, A; Gal, J; Moll, JR; Ruvinov, SB; Vinson, C | 1 |
| Bohác, M; Damborský, J; Koca, J; Monincová, M; Nagata, Y; Prokop, M; Prokop, Z; Tsuda, M | 1 |
| Carrick, KL; Topal, MD | 1 |
| Ambrose, C; Benjamin, C; Bixler, SA; Cachero, T; Day, E; Gilbride, K; Gong, D; Gorelik, L; Hsu, YM; Kalled, SL; Pelletier, M; Qian, F; Thompson, JS; Whitty, A; Zafari, M | 1 |
| FRIEDMAN, ME; ROESSLER, WG | 1 |
| WOLLENWEBER, P | 1 |
| MCCOY, TA; ORR, G; PATTERSON, MK | 1 |
| NOZAKI, Y; TANFORD, C | 1 |
| BRAUN, L | 1 |
| CHRISTENSEN, HN | 1 |
| LORINCZ, AB; RYAN, WL | 1 |
| DELALLOSA, P; JUTISZ, M; TERTRIN, C | 1 |
| GERIFFIN, G; KESNER, L; MUNTWYLER, E | 1 |
| BRUICE, TC; FRENCH, TC | 1 |
| GAEVSKAYA, MS; GERSHTEIN, LM; NOSOVA, EA; PORTUGALOV, VV | 1 |
| MORELOS, BS; ROBERTS, S | 1 |
| HYATT, MT; LEVINSON, HS | 1 |
| Dougan, DR; McRee, DE; Schryvers, AB; Shouldice, SR; Skene, RJ; Tari, LW | 1 |
| Minasov, G; Morandi, S; Prati, F; Roth, TA; Shoichet, BK | 1 |
| DeLisi, LE; Ferreira, A; Kao, HT; Porton, B | 1 |
| Langosch, D; Lindner, E; Ruan, W | 1 |
| Bowler, BE; Kristinsson, R | 1 |
| Claeysen, S; Costagliola, S; Deupí, X; Govaerts, C; Pardo, L; Urizar, E; Vassart, G | 1 |
| Gupta, A; Lewis, F; Mao, Q; Unadkat, JD; Vethanayagam, RR; Wang, H; Zhang, Y | 1 |
| Brown, RE; Kanack, AT; Malakhova, ML; Malinina, L; Patel, DJ; Pike, HM | 1 |
| Feng, YH; Qiu, R; Zeng, R; Zhou, L | 1 |
| Fanelli, F; Mizrachi, D; Segaloff, DL; Zhang, M | 1 |
| Bloodworth, LM; Hamdan, FF; Han, SJ; Jacobson, KA; Kim, SK; Li, B; Wess, J | 1 |
| Baltrusch, S; Francini, F; Lenzen, S; Tiedge, M | 1 |
| Gumbart, J; Schulten, K | 1 |
| Aasly, JO; Farrer, MJ; Pielsticker, L; Ross, OA; Toft, M | 1 |
| Blumer, JB; Gettys, TW; Kuriyama, R; Lanier, SM | 1 |
| Aldave, AJ; Bourla, N; Chen, MC; Gorin, MB; Khan, MA; Momi, RS; Rayner, SA; Sampat, KM; Sonmez, B; Yellore, VS | 1 |
| Annesi, F; Annesi, G; Carrideo, S; Cirò Candiano, IC; Civitelli, D; Condino, F; De Marco, EV; Messina, D; Morelli, M; Nicoletti, G; Novellino, F; Provenzano, G; Quattrone, A; Rocca, FE; Tarantino, P | 1 |
| Bosak, A; Gazić, I; Kovarik, Z; Vinković, V | 1 |
| Bird, TD; Griffith, A; Leis, BC; Leverenz, JB; Mata, IF; Roberts, JW; Samii, A; Schellenberg, GD; Schneer, SH; Sidransky, E; Tsuang, D; Zabetian, CP | 1 |
| Bock, H; Hilbig, A; Jardim, LB; Michelin-Tirelli, K; Rieder, CR; Saraiva-Pereira, ML; Socal, MP | 1 |
| Min, D; Yang, W | 1 |
| Akinshola, BE; Johnson, WD; Onaivi, ES; Parandaman, V; Taylor, RE | 1 |
| Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J | 1 |
| Ascenzi, P; Bolli, A; Colantonio, P; Leboffe, L; Luisi, G; Marino, M | 1 |
| Bae, CS; Choi, SH; Hwang, SH; Kim, BR; Kim, HC; Lee, BH; Lee, JH; Lee, SM; Nah, SY; Oh, JW; Pyo, MK; Rhim, H; Shin, TJ | 1 |
| Maupin, CM; McKenna, R; Silverman, DN; Tu, C; Voth, GA; Zheng, J | 1 |
| Breadmore, MC; Huo, F; Xiao, D; Yuan, H | 1 |
| Einav, Y; Hauschner, H; Koren, A; Mansour, W; Rosenberg, N; Seligsohn, U | 1 |
| Ben-Yair, R; Kahane, N; Kalcheim, C | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| Buranaprapuk, A; Liwporncharoenvong, T; Malaikaew, P; Yenjai, S | 1 |
| Blum, AP; Dougherty, DA; German, LA; Lester, HA; Van Arnam, EB | 1 |
| Antalffy, G; Enyedi, Á; Hegedűs, L; Padányi, R; Pászty, K; Varga, K | 1 |
| Anthonappa, RP; King, NM; Rabie, AB; Yan-Hui, F; You-Qiang, S | 1 |
| Kojo, S | 1 |
| Fukada, R; Kugimiya, A | 1 |
| Ahmed, M; Ikram, R; Qadir, MA | 1 |
| Boerwinkle, E; Chang, P; Coresh, J; Köttgen, A; Rebholz, CM; Selvin, E; Tin, A; Wagenknecht, LE; Yu, B; Zheng, Z | 1 |
| Fatima, S; Hafeez, A; Ijaz, AIA; Memon, AA; Waseem, M | 1 |
| Bitencourt-Ferreira, G; de Azevedo, WF; Souto, AA; Volkart, PA | 1 |
| Bergonzo, C; Christensen, M; Dharmadhikari, K; Samuels, E; Tullman, J | 1 |
| Du, D; Guo, F; Lin, H; Luo, C; Lv, S; Ye, F; Zhang, T; Zhang, Y; Zhou, L; Zhu, S | 1 |
| Altieri, AS; Baljinnyam, B; Bista, S; Dutta, S; Foor, SD; Kitsou, C; Linden, SB; Nelson, DC; Pal, U; Rana, VS; Ronzetti, M; Simeonov, A; Thakur, M; Yang, X | 1 |
| Armen, RS; Gaur, A; Lipponen, J; Wang, B; Yang, Y | 1 |
| Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Fischer, M; Görlich, D; Huyton, T; Jaiswal, M; Taxer, W | 1 |
| Bertinato, J; Hendry, A; Kenney, L; Xiao, CW | 1 |
2 review(s) available for asparagine and leucine
| Article | Year |
|---|---|
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review.
Topics: Asparagine; Binding Sites; Cellular Senescence; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Humans; Leucine; Models, Molecular; Neoplasms; Protein Kinase Inhibitors | 2019 |
223 other study(ies) available for asparagine and leucine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Characterization of L-asparagine transport systems in Stemphylium botryosum.
Topics: Ammonium Chloride; Asparagine; Azides; Biological Transport, Active; Dinitrophenols; Fungi; Hydrogen-Ion Concentration; Kinetics; Leucine; Membrane Transport Proteins; Nitrates; Structure-Activity Relationship; Temperature | 1976 |
Postsynthetic deamidation of hemoglobin Providence (beta 82 Lys replaced by Asn, Asp) and its effect on oxygen transport.
Topics: Adolescent; Adult; Asparagine; Aspartic Acid; Child, Preschool; Diphosphoglyceric Acids; Erythrocytes; Female; Glycine; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Infant; Leucine; Lysine; Male; Oxygen; Peptide Fragments; Protein Binding | 1977 |
Asparaginyl-tRNA aminoacylation levels and asparagine synthetase expression in cultured Chinese hamster ovary cells.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cell Line; Cricetinae; Cycloheximide; Emetine; Female; Kinetics; Leucine; Ligases; Mutation; Ovary; Protein Biosynthesis; RNA, Transfer; RNA, Transfer, Amino Acyl | 1979 |
Reutilization of precursor following axonal transport of [3H]proline-labeled protein.
Topics: Acetohexamide; Animals; Asparagine; Axonal Transport; Axons; Cycloheximide; Goldfish; Hydroxyproline; Leucine; Nerve Tissue Proteins; Optic Nerve; Proline; Superior Colliculi | 1977 |
Transfer RNA in aging Drosophila: II. Isoacceptor patterns.
Topics: Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Drosophila melanogaster; Histidine; Leucine; Male; RNA, Transfer; Tyrosine | 1979 |
Tyrocidine synthetase system.
Topics: Aminoacylation; Asparagine; Bacillus; Cell Division; Chromatography, DEAE-Cellulose; Glutamine; Leucine; Ligases; Methods; Molecular Weight; Multienzyme Complexes; Ornithine; Phenylalanine; Proline; Time Factors; Tyrocidine; Tyrosine; Tyrothricin; Valine | 1975 |
The relationship between length of incubation, bacterial growth and tuberculin yield of a strain of Mycobacterium tuberculosis.
Topics: Alanine; Asparagine; Aspartic Acid; Bacteriological Techniques; Chromatography, Paper; Culture Media; Glutamates; Hydrogen-Ion Concentration; Leucine; Mycobacterium tuberculosis; Time Factors; Tuberculin; Valine | 1975 |
Stimulation of L-asparaginase production in Escherichia coli by organic and amino acids.
Topics: Acids; Amino Acids; Anaerobiosis; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Lactates; Leucine; Methionine; Stereoisomerism; Valine | 1977 |
beta-Endorphin: deletion of a single amino acid residue abolishes immunoreactivity but retains opiate potency.
Topics: Amino Acid Sequence; Animals; Asparagine; Biological Assay; Camelus; Endorphins; Kinetics; Leucine; Mice; Radioimmunoassay; Structure-Activity Relationship | 1979 |
The effect on macromolecular synthesis of amino acid deprivation of hamster kidney cells.
Topics: Amino Acids; Arginine; Asparaginase; Asparagine; Cells, Cultured; DNA; Isoleucine; Kinetics; Leucine; Protein Biosynthesis; RNA; Tryptophan | 1977 |
Synthetic 63-residue RNase A analogs. Simultaneous exchange of asparagine 44 by leucine and of threonine 45 by valine.
Topics: Asparagine; Binding Sites; Hydrogen Bonding; Leucine; Ribonucleases; Threonine; Valine | 1978 |
[Investigations on the utilization of parenterally administered amino acids by premature and small-for-dates neonates. I. Free amino acids in the blood of premature and small-for dates neonates (author's transl)].
Topics: Age Factors; Amino Acids; Asparagine; Birth Weight; Fasting; Female; Glycine; Humans; Infant; Infant, Newborn; Infant, Premature; Leucine; Male; Parenteral Nutrition; Pregnancy; Sex Factors | 1975 |
Sources of ammonia for urea synthesis in isolated rat liver cells.
Topics: Alanine; Aminooxyacetic Acid; Ammonium Chloride; Animals; Asparagine; Glucose; Glutamine; Glycine; Lactates; Leucine; Liver; Ornithine; Rats; Urea; Valine | 1977 |
Regulation of Protein Synthesis in Hen's oviducts. I. Removal of extracellular and intracellular proteins and their effects on protein synthesis.
Topics: Animals; Asparagine; Body Fluids; Chickens; Deoxycholic Acid; Egg Proteins; Extracellular Space; Female; Glycine; Intracellular Fluid; Leucine; Muramidase; Ovalbumin; Oviducts; Oviposition; Proline; Time Factors | 1977 |
A role for aminoacyl-tRNA synthetases in the regulation of amino acid transport in mammalian cell lines.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Asparagine; Biological Transport, Active; Cell Line; Kinetics; Leucine; Leucine-tRNA Ligase; Mutation; Temperature | 1977 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Selection by [3H] amino acids of CHO-cell mutants with altered leucyl- and asparagyl-transfer RNA synthetases.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Cell Line; Cricetinae; Culture Media; Genes, Recessive; Hybrid Cells; In Vitro Techniques; Leucine; Leucine-tRNA Ligase; Mutation; Phenotype; Selection, Genetic; Valine | 1975 |
Structure of the EF corner favors deamidation of asparaginyl residues in hemoglobin: the example of Hb La Roche-sur-Yon [beta 81 (EF5) Leu----His].
Topics: Adolescent; Amino Acid Sequence; Asparagine; Chromatography, High Pressure Liquid; Female; Hemoglobins, Abnormal; Histidine; Humans; Isoelectric Focusing; Leucine; Models, Molecular; Molecular Sequence Data; Oxygen; Protein Conformation; Protein Processing, Post-Translational | 1992 |
Structural and functional effects of mutations altering the subunit interface of mitochondrial malate dehydrogenase.
Topics: Acetates; Acetic Acid; Amino Acid Sequence; Asparagine; Aspartic Acid; Blotting, Western; Chromatography, Gel; Codon; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Macromolecular Substances; Malate Dehydrogenase; Mitochondria; Molecular Sequence Data; Mutagenesis; Saccharomyces cerevisiae; Structure-Activity Relationship | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Improving the thermostability of the neutral protease of Bacillus stearothermophilus by replacing a buried asparagine by leucine.
Topics: Asparagine; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Geobacillus stearothermophilus; Hydrogen Bonding; Leucine; Metalloendopeptidases; Molecular Structure; Mutagenesis, Site-Directed; Temperature | 1991 |
Biosynthesis of sulfated asparagine-linked complex carbohydrate units of calf thyroglobulin.
Topics: Animals; Asparagine; Carbon Radioisotopes; Cattle; Glucose; Glycopeptides; In Vitro Techniques; Kinetics; Leucine; Mannose; Oligosaccharides; Subcellular Fractions; Sulfates; Sulfur Radioisotopes; Thyroglobulin; Thyroid Gland; Tritium; Trypsin | 1988 |
Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of Leu129 or Asp119.
Topics: Amino Acid Sequence; Asparagine; Cross-Linking Reagents; Ethyldimethylaminopropyl Carbodiimide; Leucine; Muramidase; Protein Engineering | 1987 |
The activation of Mg++-dependent ATPase by aspartic and glutamic acids.
Topics: Adenosine Triphosphatases; Alanine; Asparagine; Aspartic Acid; Cell Membrane; Cell Membrane Permeability; Depression, Chemical; Enzyme Activation; Erythrocytes; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine; Magnesium; Potassium; Saponins; Serine; Sodium | 1970 |
Dynamics of axoplasmic transport in the optic system of the rat.
Topics: Alanine; Animals; Asparagine; Axonal Transport; Circadian Rhythm; Estrus; Female; Leucine; Male; Neurons; Pregnancy; Proline; Rats; Retina; Sex Factors; Solubility; Time Factors; Tritium; Visual Pathways | 1974 |
Chromatographic analysis of the bleeding sap of inoculated and non-inoculated soya plants.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Paper; Glutamine; Glycine max; Injections; Leucine; Nitrogen; Rhizobium; Serine; Valine | 1967 |
L-asparaginase and blastogenesis.
Topics: Asparaginase; Asparagine; Carbon Isotopes; Culture Media; Glycine; Humans; In Vitro Techniques; Leucine; Lymphocyte Activation; Lymphocytes; Protein Biosynthesis | 1969 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
Preparation and properties of smooth muscle myosin from horse esophagus.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Asparagine; Aspartic Acid; Calcium; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Edetic Acid; Enzyme Activation; Esophagus; Ethylmaleimide; Glycine; Horses; Leucine; Lysine; Magnesium; Muscle Proteins; Muscle, Smooth; Muscles; Organ Specificity; Osmolar Concentration; Phosphorus; Potassium Chloride; Proline; Rabbits; Sulfhydryl Compounds; Temperature; Ultracentrifugation | 1970 |
Evidence for de novo synthesis of asparagine synthetase in gamma irradiated potatoes.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Leucine; Plants, Edible; Radiation Effects | 1971 |
II. Pharmacology of angiotensin antagonists.
Topics: Angiotensin II; Animals; Asparagine; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Isoleucine; Leucine; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Rats; Sarcosine; Serotonin; Stomach | 1973 |
L-asparaginase-induced alterations of Burkitt's lymphoma cells.
Topics: Antigens, Neoplasm; Asparaginase; Asparagine; Burkitt Lymphoma; Cell Count; Cell Line; Cell Membrane; Cell Survival; DNA, Neoplasm; Herpesvirus 4, Human; Humans; Leucine; Mutation; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1973 |
Triphosphate spin-label studies of allosteric interactions in hemoglobin.
Topics: Adenosine Triphosphate; Allosteric Regulation; Arginine; Asparagine; Aspartic Acid; Australia; Binding Sites; Cyanides; Electron Spin Resonance Spectroscopy; Ferricyanides; Glycerophosphates; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Leucine; Maryland; Mathematics; Models, Biological; Mutation; Phosphoric Acids; Piperidines; Protein Binding; Protein Conformation; Spin Labels | 1973 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
A modified lithium buffer system for analysis of acidic and neutral amino acids in physiological fluids.
Topics: Amino Acids; Asparagine; Blood Chemical Analysis; Body Fluids; Buffers; Citrates; Cystine; Glutamine; Humans; Hydrogen-Ion Concentration; Leucine; Lithium; Methods; Urine | 1974 |
Analysis of isoaccepting tRNAs during the growth phase mitotic cycle of Physarum polycephalum.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Asparagine; Cell Division; Chromatography, Ion Exchange; Codon; Genetic Code; Glycine; Histidine; Isoleucine; Leucine; Mitosis; Myxomycetes; Protein Biosynthesis; RNA, Transfer; Tritium; Tryptophan; Valine | 1974 |
Effect of asparagine and glutamine deficiency on normal and leukemic cells.
Topics: Animals; Asparagine; Carbon Radioisotopes; Cell Count; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Glutamine; Humans; Lectins; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocytes; Mice; Neoplasm Proteins | 1973 |
The presence of N-(purin-6-ylcarbamoyl)threonine in transfer ribonucleic acid species whose codons begin with adenine.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Arginine; Asparagine; Benzoates; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Genetic Code; Glycolates; Isoleucine; Leucine; Lysine; Methionine; Purine Nucleotides; RNA, Bacterial; RNA, Transfer; Serine; Succinimides; Threonine; Tritium | 1972 |
[Chemical studies on colibiogen].
Topics: Alanine; Asparagine; Biological Products; Escherichia coli; Galactose; Glucose; Glutamates; Glycine; Leucine; Lysine; Palmitic Acids; Stearic Acids; Xylose | 1973 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Effect of asparagine on growth and protein synthesis in weanling rats.
Topics: Administration, Oral; Animal Feed; Animals; Asparagine; Aspartic Acid; Carbon Radioisotopes; Caseins; Citrates; Injections, Intraperitoneal; Leucine; Liver; Male; Muscles; Nutritional Requirements; Protein Biosynthesis; Protein Hydrolysates; Quaternary Ammonium Compounds; Rats; Weaning | 1973 |
In vitro synthesis of a specific protein viz. Asparagine synthetase by nuclear fraction from gamma irradiated potato buds.
Topics: Ammonia; Asparagine; Aspartic Acid; Carbon Radioisotopes; Cell Nucleus; Cycloheximide; Dactinomycin; Enzyme Induction; Hydroxamic Acids; Leucine; Ligases; Plant Cells; Plants; Puromycin; Radiation Effects | 1973 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Highly restricted specificity of the serine proteinase aspergillopeptidase B.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspergillus; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Glutamates; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Methods; Oxidation-Reduction; Peptide Fragments; Peptide Hydrolases; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tyrosine; Zinc | 1974 |
Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and -resis
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Cell-Free System; Culture Techniques; Escherichia coli; Female; Glutamine; Leucine; Lymphoma; Male; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rabbits; Rats | 1968 |
The amino acid sequences of some tryptic peptides from porcine pepsinogen.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Asparagine; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Enzyme Precursors; Glycine; Histidine; Leucine; Lysine; Pepsin A; Peptides; Proline; Swine; Trypsin; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Glutaminase activity of L-asparagine amidohydrolase.
Topics: Asparaginase; Asparagine; Azaserine; Carbon Isotopes; Escherichia coli; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine | 1969 |
Antineoplastic activity of highly purified bacterial glutaminases.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacteria; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Escherichia coli; Female; Glutaminase; Glutamine; Leucine; Mice; Neoplasm Proteins | 1970 |
Studies on the glutaminase activity of E. coli asparaginase in tissue culture.
Topics: Asparaginase; Asparagine; Carbon Isotopes; Depression, Chemical; Drug Resistance; Eosinophils; Escherichia coli; Glutamates; Glutaminase; Glutamine; HeLa Cells; Humans; Leucine; Leukocytes; Lymphocyte Activation; Mitosis; Monocytes; Neutrophils; Stimulation, Chemical; Thymidine; Uridine | 1970 |
Biosynthesis of branched-chain fatty acids. IV. Factors affecting relative abundance of fatty acids produced by Bacillus subtilis.
Topics: Asparagine; Bacillus subtilis; Biotin; Chromatography, Gas; Culture Media; Fatty Acids; Isoleucine; Leucine; Valine | 1966 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Stability of methionine hydroxy analog in rumen fluid and its conversion in vitro to methionine by calf liver and kidney.
Topics: Aminobutyrates; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Biotransformation; Carbon Isotopes; Cattle; Chromatography, Thin Layer; Culture Techniques; Ethers; Female; Glutamine; Kidney; Leucine; Liver; Methionine; Microsomes; Microsomes, Liver; Rumen | 1972 |
Induction of asparagine synthetase in gamma-irradiated potatoes.
Topics: Asparagine; Carbon Isotopes; Enzyme Induction; Leucine; Ligases; Plants; Radiation Effects | 1972 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Uptake and incorporation of amino acids by the preimplantation mouse embryo.
Topics: Amino Acids; Animals; Asparagine; Carbon Isotopes; Culture Media; Embryo, Mammalian; Female; Fertilization; Glutamine; Leucine; Mice; Ovum | 1971 |
[Findings concerning the decrease of amino acid content during ther heating of proteins].
Topics: Amino Acids; Asparagine; Caseins; Chromatography, Paper; Cystine; Dietary Proteins; Food; Food Analysis; Glutamates; Hot Temperature; Leucine; Lysine; Methionine; Time Factors; Valine | 1971 |
5-Diazo-4-oxo-L-norvaline: reactive asparagine analog with biological specificity.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Carbon Isotopes; Culture Techniques; DNA; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Protein Biosynthesis; RNA; Spectrum Analysis; Thymidine; Ultraviolet Rays; Valine | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
[On the capability of the members of the genus Aeromonas to use amino acids as sole source of carbon].
Topics: Aeromonas; Alanine; Amino Acids; Arginine; Asparagine; Culture Media; Glutamates; Histidine; Leucine; Methionine; Phenylalanine; Serine; Species Specificity | 1969 |
Prediction and explanation of chemical mutation sites.
Topics: Arginine; Asparagine; Genetic Code; Genetics, Microbial; Glycine; Leucine; Models, Chemical; Mutagens; Mutation; Nucleotides; Phenylalanine; Proline; RNA, Viral; Serine; Tobacco Mosaic Virus | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
The specific nonenzymatic cleavage of bovine ribonuclease with hydroxylamine.
Topics: Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Collagen; Glycine; Hydroxylamines; Imides; Leucine; Pancreas; Ribonucleases | 1970 |
The amino acid sequence of T4 phage lysozyme. IV. Dilute acid hydrolysis and the order of tryptic peptides.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Coliphages; Electrophoresis; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Leucine; Muramidase; Peptides; Trypsin; Valine | 1970 |
[The qualitative and quantitative demonstration of free amino acids in tonsil tissue with the use of paper chromatography].
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Asparagine; Child; Child, Preschool; Chromatography, Paper; Glutamine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Methods; Middle Aged; Palatine Tonsil; Phenylalanine; Valine | 1970 |
Isolation of enzyme-bound peptide intermediates in tyrocidine biosynthesis.
Topics: Anti-Bacterial Agents; Asparagine; Bacillus; Carbon Isotopes; Chemical Precipitation; Chromatography, Thin Layer; Esters; Leucine; Ornithine; Peptide Biosynthesis; Phenylalanine; Proline; Trichloroacetic Acid | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
L-asparaginase: early findings and current studies on the metabolism of L-asparagine in lymphoma cells.
Topics: Amino Acyl-tRNA Synthetases; Asparaginase; Asparagine; Aspartic Acid; Cell Line; Chromatography, DEAE-Cellulose; Drug Resistance; Kinetics; Leucine; Lymphoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Transfer | 1970 |
Rapid transport of protein in the optic system of the goldfish.
Topics: Acetylcholinesterase; Animals; Asparagine; Biological Transport; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Thin Layer; Cyprinidae; DNA; Hydrolysis; Kinetics; Leucine; Microsomes; Mitochondria; Myelin Sheath; Nerve Tissue Proteins; Optic Nerve; Oxidoreductases; Proline; Ribosomes; RNA; Synaptic Vesicles; Temperature; Tritium | 1971 |
Energy metabolism of proteins and amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Temperature Regulation; Caseins; Dietary Proteins; Gelatin; Glutamates; Glycine; Humans; Leucine; Muscles; Nutritional Physiological Phenomena; Proteins; Rats; Tyrosine | 1971 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The action of sparsomycin and gougerotin on virus growth.
Topics: Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Carbon Isotopes; Encephalitis Viruses; Glycine; Herpesviridae; Influenza A virus; Leucine; Lysine; Molecular Biology; Newcastle disease virus; Phenylalanine; Proline; RNA, Messenger; Vaccinia virus; Virus Replication; Viruses | 1968 |
The effects of L-asparaginase on the amino acid incorporation of mouse lymphoid tumors.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Leucine; Lymphoma; Mice; Neoplasms, Experimental; Tritium | 1968 |
Terminal animo acid residues of ovine follicle stimulating hormone.
Topics: Amino Acids; Animals; Asparagine; Carboxypeptidases; Female; Follicle Stimulating Hormone; Leucine; Leucyl Aminopeptidase; Protein Hydrolysates; Sheep | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver.
Topics: Amino Acids; Animals; Arginine; Asparagine; In Vitro Techniques; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Perfusion; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Tryptophan; Valine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Amino acid composition and end group analysis of cobrotoxin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chromatography; Leucine; Molecular Weight; Snakes; Tritium; Venoms | 1969 |
Synthesis of potentially cytoactive amino acid amide mustards.
Topics: Alanine; Antineoplastic Agents; Asparagine; Chemistry, Organic; Culture Techniques; Glutamates; Glycine; Leucine; Nitrogen Mustard Compounds; Organic Chemistry Phenomena; Phenylalanine | 1966 |
Photochemical synthesis of amino acids from paraformaldehyde catalyzed by inorganic agents.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Catalysis; Chemistry, Organic; Chromatography, Paper; Cobalt; Copper; Formaldehyde; Iron; Leucine; Light; Lysine; Nitrates; Organic Chemistry Phenomena; Quaternary Ammonium Compounds; Sulfides; Valine | 1966 |
[The influence of temperature on the content of some carbohydrates and amino acids in Spirogyra].
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, Paper; Eukaryota; Fructose; Glucose; Glutamates; Glutamine; Leucine; Nitrogen; Serine; Starch; Temperature; Valine | 1966 |
The occurrence of hypotaurine and other sulfur-containing amino acids in seminal plasma and spermatozoa of boar, bull and dog.
Topics: Alanine; Amino Acids; Animals; Asparagine; Cattle; Dogs; Electrophoresis; Glutamates; Glycine; In Vitro Techniques; Leucine; Male; Semen; Serine; Spermatozoa; Swine; Taurine; Valine | 1966 |
[An attempt at the use of autoradiography for the study of the chemical composition of cellular structures (experiments using the oocytes of the frog)].
Topics: Adenine; Amino Acids; Animals; Anura; Asparagine; Autoradiography; Carbon Isotopes; Female; Glutamates; Glycine; Histocytochemistry; Leucine; Methionine; Methods; Nucleosides; Ovum; Phenylalanine; Tritium; Tyrosine | 1966 |
Rate constants of hydrated electron reactions with peptides and proteins.
Topics: Alanine; Albumins; Asparagine; Electrons; Gelatin; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muramidase; Peptides; Phenylalanine; Proline; Proteins; Ribonucleases; Tryptophan; Tyrosine; Valine | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Differences in the production of L-asparagine in asparaginase-sensitive and resistant lymphoma cells.
Topics: Amidohydrolases; Animals; Asparagine; Carbon Isotopes; Culture Techniques; Leucine; Lymphoma; Mice; Tritium | 1967 |
Effects of amino acids and amino acid analogues on lysosomal protein degradation in isolated rat hepatocytes.
Topics: alpha-Fetoproteins; Amino Acids; Animals; Asialoglycoproteins; Asparagine; Fetuins; Leucine; Liver; Lysosomes; Male; Propylamines; Proteins; Rats; Rats, Inbred Strains; Vacuoles | 1981 |
Cellular effects of ornithine decarboxylase induction in cells maintained with a salts/glucose medium.
Topics: Animals; Asparagine; Bucladesine; Carboxy-Lyases; Cell Line; Culture Media; Enzyme Induction; Glucose; Leucine; Ornithine Decarboxylase; Salts; Thymidine; Uridine | 1981 |
The stimulus-secretion coupling of amino acid-induced insulin release metabolic interaction of L-asparagine and L-leucine in pancreatic islets.
Topics: Animals; Asparagine; Carbon Radioisotopes; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Rats | 1984 |
The stimulus-secretion coupling of amino acid-induced insulin release. Secretory and oxidative response of pancreatic islets to L-asparagine.
Topics: Amino Acids; Animals; Asparagine; Calcium; Drug Interactions; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Malates; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Theophylline | 1984 |
The stimulus-secretion coupling of amino acid-induced insulin release. Inhibition of islet respiration and insulin release by aminooxyacetate.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Animals; Asparagine; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Oxygen Consumption; Rats | 1984 |
Practical gas-liquid chromatographic method for the determination of amino acids in human serum.
Topics: Amino Acids; Arginine; Asparagine; Chromatography, Gas; Formates; Formic Acid Esters; Glutamine; Humans; Isoleucine; Leucine; Tyrosine | 1982 |
Leucine inhibition of autophagic vacuole formation in isolated rat hepatocytes.
Topics: Animals; Asparagine; Autophagy; Leucine; Liver; Lysosomes; Male; Microscopy, Electron; Phagocytosis; Proteins; Rats | 1981 |
Effects of amino acid analogues on protein degradation in isolated rat hepatocytes.
Topics: Amino Acids; Animals; Asparagine; Autophagy; Glutamine; Histidine; Leucine; Liver; Male; Phenylalanine; Proteins; Rats; Structure-Activity Relationship; Tryptophan | 1981 |
Influence of individual amino acids on incorporation of [14C]leucine by rat liver ribosomes.
Topics: Amino Acids; Amino Acids, Essential; Animals; Asparagine; Aspartic Acid; Glutamates; Glutamine; Leucine; Liver; Rats; Ribosomal Proteins; Ribosomes | 1980 |
Electrostatic dominoes: long distance propagation of mutational effects in photosynthetic reaction centers of Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Electron Transport; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Point Mutation; Recombinant Proteins; Rhodobacter capsulatus | 1995 |
Functional consequences of mutation Asn326-->Leu in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+, K(+)-ATPase.
Topics: Adenosine Triphosphate; Animals; Asparagine; Cell Line; Cell Membrane; Gene Expression; Kidney; Leucine; Mutagenesis, Site-Directed; Phosphorylation; Potassium; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Stabilizing and destabilizing effects of placing beta-branched amino acids in protein alpha-helices.
Topics: Acetonitriles; Amino Acids, Branched-Chain; Asparagine; Bacteriophage T4; Base Sequence; Circular Dichroism; Computer Simulation; Drug Stability; Electrophoresis, Polyacrylamide Gel; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Muramidase; Mutation; Oligonucleotides; Protein Structure, Secondary; Serine; Valine | 1994 |
Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzyme.
Topics: Alcohol Dehydrogenase; Asparagine; Base Sequence; Binding Sites; Fomepizole; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Pyrazoles; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1994 |
Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX.
Topics: Adult; Amino Acid Sequence; Asparagine; Base Sequence; Bernard-Soulier Syndrome; Blood Platelets; Blotting, Western; DNA; DNA Primers; Female; Genetic Variation; Humans; Leucine; Male; Molecular Sequence Data; Pedigree; Platelet Aggregation; Platelet Membrane Glycoproteins; Point Mutation; Polymerase Chain Reaction; Reference Values; Serine | 1994 |
Cis- and trans-acting elements involved in amino acid regulation of asparagine synthetase gene expression.
Topics: Amino Acids; Animals; Asparagine; Aspartate-Ammonia Ligase; Base Sequence; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Cricetinae; DNA; Exons; Gene Expression Regulation, Enzymologic; Glutamine; HeLa Cells; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Sequence Deletion; Sequence Homology, Nucleic Acid; Transfection | 1993 |
Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells.
Topics: Adenine; Adenocarcinoma; Asparagine; Autophagy; Carbon Radioisotopes; Carcinogens; Cell Differentiation; Cell Line; Chloroquine; Colonic Neoplasms; Ethers, Cyclic; Glycoproteins; Humans; Kinetics; Leucine; Lysosomes; Mannose; Okadaic Acid; Polysaccharides; Tritium; Tumor Cells, Cultured | 1993 |
Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Base Sequence; Binding Sites; Corticosterone; Coumarins; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Hydroxyprogesterones; Leucine; Mice; Mice, Inbred AKR; Molecular Sequence Data; Mutagenesis, Site-Directed; Progesterone; Spectrophotometry; Steroid Hydroxylases; Structure-Activity Relationship | 1993 |
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Cloning, Molecular; Collagenases; Enzyme Activation; Enzyme Precursors; Gelatinases; Humans; Kinetics; Leucine; Matrix Metalloproteinase 1; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Substrate Specificity; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tyrosine | 1996 |
A point mutation leads to altered product specificity in beta-lactamase catalysis.
Topics: Asparagine; Bacillus; beta-Lactamases; Carboxypeptidases; Catalysis; Chromatography, High Pressure Liquid; Leucine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Penicillin G; Point Mutation; Structure-Activity Relationship; Substrate Specificity | 1997 |
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Topics: Administration, Oral; Adult; Aged; Alanine; Amino Acids; Asparagine; C-Peptide; Codon; DNA-Binding Proteins; Female; Glucose; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Serine; Transcription Factors; Valine | 1997 |
The residues Leu 93 and Asp 96 act independently in the bacteriorhodopsin photocycle: studies with the leu 93-->Ala, Asp 96-->Asn double mutant.
Topics: Alanine; Asparagine; Aspartic Acid; Bacteriorhodopsins; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Leucine; Light; Models, Molecular; Mutagenesis, Site-Directed; Photochemistry; Point Mutation; Protein Conformation; Recombinant Proteins; Schiff Bases; Spectrophotometry; Time Factors | 1996 |
Structures of wild-type chloromet and L103N hydroxomet Themiste zostericola myohemerythrins at 1.8 A resolution.
Topics: Animals; Asparagine; Binding Sites; Crystallography, X-Ray; Hemerythrin; Hydrogen Bonding; Kinetics; Leucine; Ligands; Models, Molecular; Nematoda; Pigments, Biological; Protein Conformation; Recombinant Proteins; Water | 1997 |
Cooperative transformation of NIH3T3 cells by G alpha12 and Rac1.
Topics: 3T3 Cells; Animals; Asparagine; cdc42 GTP-Binding Protein; Cell Cycle Proteins; COS Cells; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Hemagglutinins; JNK Mitogen-Activated Protein Kinases; Leucine; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mutagenesis; Plasmids; Poly(ADP-ribose) Polymerases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Transformation, Genetic; Valine | 1997 |
A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket.
Topics: Animals; Asparagine; Binding Sites; Circular Dichroism; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Horses; Leucine; Molecular Sequence Data; Mutation; Myocardium; Myoglobin; Nucleic Acid Conformation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectrophotometry | 1997 |
Structural determinants of processing and secretion of the Haemophilus influenzae hap protein.
Topics: Amino Acid Sequence; Asparagine; Bacterial Outer Membrane Proteins; Base Sequence; Cell Membrane; DNA, Bacterial; Haemophilus influenzae; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Secondary; Serine Endopeptidases; Structure-Activity Relationship | 1997 |
Glu78, from the conserved PEWY sequence of subunit IV, has a key function in cytochrome b6f turnover.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Transformation, Genetic | 1998 |
A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriophage lambda; Base Sequence; DNA-Directed RNA Polymerases; Escherichia coli; Leucine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis; Peptide Chain Termination, Translational; Phenylalanine; Promoter Regions, Genetic; Protein Binding; Sigma Factor; Transcription, Genetic; Viral Proteins | 1998 |
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
Topics: Adult; Amino Acid Substitution; Asparagine; C-Peptide; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Genetic Variation; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Islets of Langerhans; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Serine; Transcription Factors; White People | 1998 |
H-bonding maintains the active site of type 1 copper proteins: site-directed mutagenesis of Asn38 in poplar plastocyanin.
Topics: Asparagine; Binding Sites; Glutamine; Hydrogen Bonding; Leucine; Mutagenesis, Site-Directed; Plastocyanin; Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Threonine; Trees | 1999 |
Evolution of a protein fold in vitro.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Circular Dichroism; Hydrogen Bonding; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Viral Proteins; Viral Regulatory and Accessory Proteins | 1999 |
Alternative roles for putative ice-binding residues in type I antifreeze protein.
Topics: Amino Acid Sequence; Antifreeze Proteins; Asparagine; Binding Sites; Glycoproteins; Ice; Leucine; Molecular Sequence Data | 1999 |
1H, 15N and 13C resonance assignments for the 22 kDa LC1 light chain from Chlamydomonas outer arm dynein.
Topics: Animals; Asparagine; Carbon Isotopes; Chlamydomonas; Dyneins; Hydrogen; Leucine; Leucine-Rich Repeat Proteins; Macromolecular Substances; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins | 1999 |
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Topics: Aminobutyrates; Asparagine; Binding Sites; Computer Simulation; Crystallography, X-Ray; HIV Protease Inhibitors; HIV-1; Isoleucine; Leucine; Lysine; Models, Molecular; Molecular Mimicry; Oligopeptides; Peptides, Cyclic; Phenylalanine; Protein Conformation; Stereoisomerism; Valine | 1999 |
Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.
Topics: Amino Acid Substitution; Arginine; Asparagine; Aspartic Acid; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporin Resistance; Cysteine; Enzyme Inhibitors; Leucine; Methionine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Penicillin Resistance; Phenotype | 1999 |
Recombinant hemoglobin(alpha 29leucine --> phenylalanine, alpha 96valine --> tryptophan, beta 108asparagine --> lysine) exhibits low oxygen affinity and high cooperativity combined with resistance to autoxidation.
Topics: Amino Acid Substitution; Asparagine; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Humans; Kinetics; Leucine; Lysine; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Phenylalanine; Protein Binding; Recombinant Proteins; Tryptophan; Valine | 1999 |
Expression and function of the gonadotropin-releasing hormone receptor are dependent on a conserved apolar amino acid in the third intracellular loop.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Conserved Sequence; COS Cells; Gonadotropin-Releasing Hormone; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Kinetics; Leucine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Structure, Secondary; Radioligand Assay; Receptors, LHRH; Transfection; Tyrosine | 1999 |
Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein.
Topics: Adenoviruses, Human; Animals; Asparagine; Binding Sites; Capsid; Capsid Proteins; CHO Cells; Circular Dichroism; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cricetinae; Humans; Leucine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Virus | 2000 |
Necessity of conserved asparagine residues in the leucine-rich repeats of platelet glycoprotein Ib alpha for the proper conformation and function of the ligand-binding region.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Asparagine; Binding Sites, Antibody; Cell Adhesion; Cell Movement; CHO Cells; Conserved Sequence; Cricetinae; Humans; Leucine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; Transfection; von Willebrand Factor | 2000 |
Modeling the effects of mutations on the free energy of the first electron transfer from QA- to QB in photosynthetic reaction centers.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Electron Transport; Energy Transfer; Glutamic Acid; Glutamine; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter capsulatus; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Water | 2000 |
Interruption of the internal water chain of cytochrome f impairs photosynthetic function.
Topics: Animals; Asparagine; Brassica; Chlamydomonas reinhardtii; Crystallography, X-Ray; Cyanobacteria; Cytochromes; Cytochromes f; Glutamine; Hydrogen Bonding; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthesis; Plant Proteins; Protozoan Proteins; Sequence Homology, Amino Acid; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Water | 2000 |
Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.
Topics: Alanine; Animals; Anti-HIV Agents; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enfuvirtide; Guanosine 5'-O-(3-Thiotriphosphate); HIV Envelope Protein gp41; Humans; Kinetics; Leucine; Ligands; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Peptide Biosynthesis; Peptide Fragments; Phenylalanine; Protein Binding; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium; Tryptophan | 2000 |
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Topics: Arginine; Asparagine; Aspartate Aminotransferases; Catalytic Domain; Crystallography, X-Ray; Dicarboxylic Acids; DNA Mutational Analysis; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Lysine; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Static Electricity; Structure-Activity Relationship | 2001 |
Amino acid residues in ribonuclease MC1 from bitter gourd seeds which are essential for uridine specificity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Arginine; Asparagine; Cucurbitaceae; Enzyme Activation; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Ribonucleases; Seeds; Substrate Specificity; Uridine; Valine | 2001 |
Hydrophobic analogues of the winter flounder 'antifreeze' protein.
Topics: Alanine; Amino Acid Substitution; Aminobutyrates; Animals; Antifreeze Proteins; Asparagine; Aspartic Acid; Flounder; Freezing; Ice; Isoleucine; Leucine; Protein Engineering; Protein Structure, Secondary; Structure-Activity Relationship; Threonine | 2001 |
Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin.
Topics: Alanine; Asparagine; Binding, Competitive; Calcium; Chemokine CCL11; Chemokines, CC; Cytokines; Dose-Response Relationship, Drug; Humans; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Threonine; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
Control of metalloprotein reduction potential: the role of electrostatic and solvation effects probed on plastocyanin mutants.
Topics: Asparagine; Electrochemistry; Glutamine; Hydrogen Bonding; Leucine; Metalloproteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Plastocyanin; Quantitative Structure-Activity Relationship; Solvents; Spinacia oleracea; Static Electricity; Surface Properties; Thermodynamics | 2001 |
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.
Topics: Acyltransferases; Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Arsenate Reductases; Arsenite Transporting ATPases; Asparagine; Catalysis; Cattle; Ion Pumps; Kinetics; Leucine; Multienzyme Complexes; Mutagenesis, Site-Directed; Myristic Acid; Peptide Fragments; Phenylalanine; Rabbits; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Spectrometry, Fluorescence; Substrate Specificity; Swine; Threonine | 2001 |
Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Asparagine; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Drug Resistance; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Penicillin-Binding Proteins; Penicillins; Protein Binding; Protein Conformation; Streptococcus pneumoniae; Threonine | 2001 |
Mutation of N304 to leucine in Streptomyces clavuligerus deacetoxycephalosporin C synthase creates an enzyme with increased penicillin analogue conversion.
Topics: Amino Acid Substitution; Asparagine; Biological Assay; Chromatography, High Pressure Liquid; Computational Biology; Intramolecular Transferases; Leucine; Models, Molecular; Mutation; Penicillin-Binding Proteins; Penicillins; Protein Conformation; Streptomyces | 2001 |
The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase.
Topics: Asparagine; Binding Sites; Catalysis; Cholesterol Oxidase; Crystallization; Crystallography, X-Ray; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Kinetics; Leucine; Mutagenesis, Site-Directed; Oxidation-Reduction; Recombinant Proteins; Static Electricity; Streptomyces; Substrate Specificity | 2001 |
Amino acid runs in eukaryotic proteomes and disease associations.
Topics: Animals; Arabidopsis; Asparagine; Caenorhabditis elegans; Drosophila melanogaster; Genome; Genome, Human; Glutamine; Humans; Leucine; Saccharomyces cerevisiae; Serine; Species Specificity; Transcription, Genetic | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Mutants of the CuA site in cytochrome c oxidase of Rhodobacter sphaeroides: I. Spectral and functional properties.
Topics: Amino Acid Substitution; Asparagine; Cell Membrane; Copper; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glycine; Heme; Histidine; Iron; Kinetics; Leucine; Manganese; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Structure, Secondary; Proton Pumps; Rhodobacter sphaeroides; Spectrometry, Fluorescence; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 2002 |
Mutants of the CuA site in cytochrome c oxidase of Rhodobacter sphaeroides: II. Rapid kinetic analysis of electron transfer.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Copper; Electron Transport; Electron Transport Complex IV; Histidine; Kinetics; Leucine; Ligands; Methionine; Organometallic Compounds; Photolysis; Rhodobacter sphaeroides; Ruthenium; Ultracentrifugation | 2002 |
Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior.
Topics: Amino Acids; Asparagine; Binding Sites; Calorimetry, Differential Scanning; Escherichia coli; Fungal Proteins; Hydrogen-Ion Concentration; Leucine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Temperature; Thermodynamics; Ubiquitin; Valine | 2002 |
Topological analysis of peripherin/rds and abnormal glycosylation of the pathogenic Pro216-->Leu mutation.
Topics: Amino Acid Sequence; Animals; Asparagine; Glycosylation; Intermediate Filament Proteins; Leucine; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Peripherins; Point Mutation; Proline; Recombinant Proteins; Retinal Degeneration | 2002 |
The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73.
Topics: Animals; Asparagine; Cathepsin B; Cathepsin L; Cathepsins; Chickens; Crystallography, X-Ray; Cystatins; Cysteine Endopeptidases; Glutamine; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence | 2002 |
A heterodimerizing leucine zipper coiled coil system for examining the specificity of a position interactions: amino acids I, V, L, N, A, and K.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Chickens; Circular Dichroism; Dimerization; Isoleucine; Leucine; Leucine Zippers; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Transcription Factors; Ultracentrifugation; Valine | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Circular Dichroism; Crystallography, X-Ray; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA Ligases; DNA Restriction Enzymes; DNA Topoisomerases; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Histidine; Leucine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Proteins; Sequence Homology, Amino Acid; Temperature; Ultraviolet Rays | 2003 |
Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF.
Topics: Animals; Arthritis, Rheumatoid; Asparagine; B-Cell Activating Factor; B-Cell Activation Factor Receptor; B-Cell Maturation Antigen; B-Lymphocytes; Cell Membrane; Cell Separation; Cell Survival; CHO Cells; Cricetinae; Dimerization; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoglobulin G; Leucine; Lupus Erythematosus, Systemic; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phenotype; Proline; Protein Binding; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Spleen; Tumor Necrosis Factor-alpha; Valine | 2003 |
Growth of Listeria monocytogenes in defined media.
Topics: Alanine; Arginine; Asparagine; Culture Media; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Listeria monocytogenes; Methionine; Proteins; Valine | 1961 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
CARBON DIOXIDE FIXATION IN THE JA-1 SARCOMA IN VITRO.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fumarates; Glutamates; Glutamine; In Vitro Techniques; Isoleucine; Leucine; Metabolism; Propionates; Proteins; Pyruvates; Sarcoma; Sarcoma, Experimental; Succinates | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
CATALYTIC REACTIONS INVOLVING AZOMETHINES. IV. RATES AND EQUILIBRIA OF IMINE FORMATION WITH PYRIDINE-4-ALDEHYDE AND VARIOUS AMINO ACIDS.
Topics: Alanine; Aldehydes; Amino Acids; Arginine; Asparagine; Aspartic Acid; Azo Compounds; Biochemical Phenomena; Biochemistry; Glutamates; Glycine; Imines; Leucine; Phenylalanine; Pyridines; Research; Serine; Spectrophotometry; Thiosemicarbazones; Valine | 1964 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
REGULATION OF CEREBRAL METABOLISM OF AMINO ACIDS. IV. INFLUENCE OF AMINO ACID LEVELS ON LEUCINE UPTAKE, UTILIZATION AND INCORPORATION INTO PROTEIN IN VIVO.
Topics: Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Blood Volume; Brain Chemistry; Cerebral Cortex; Diet; Extracellular Space; Glutamates; Glutamine; Inulin; Leucine; Nerve Tissue Proteins; Proteins; Rats; Research; Serum Albumin; Serum Albumin, Radio-Iodinated | 1965 |
Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores.
Topics: Alanine; Arginine; Asparagine; Bacillus; Bacillus megaterium; Culture Media; Cysteine; Hot Temperature; Leucine; Nitrates; Nitrogen; Proline; Spores, Bacterial; Valine | 1962 |
Presence of ferric hydroxide clusters in mutants of Haemophilus influenzae ferric ion-binding protein A.
Topics: Alanine; Asparagine; Bacterial Outer Membrane Proteins; Bacterial Proteins; Crystallization; Crystallography, X-Ray; Ferric Compounds; Haemophilus influenzae; Histidine; Iron-Binding Proteins; Leucine; Mutagenesis, Site-Directed; Periplasmic Binding Proteins; Protein Binding; Solutions; Transferrin | 2003 |
Thermodynamic cycle analysis and inhibitor design against beta-lactamase.
Topics: Alanine; Asparagine; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Hydrogen Bonding; Leucine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins; Thermodynamics | 2003 |
A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia.
Topics: Animals; Animals, Newborn; Asparagine; Base Sequence; Brain; Cyclin-Dependent Kinases; DNA Mutational Analysis; Embryo, Mammalian; Enzyme Inhibitors; Exons; Family Health; Female; Genotype; Hippocampus; Humans; Immunoblotting; Leucine; Linkage Disequilibrium; Male; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neuropeptides; Pedigree; Phosphoproteins; Phosphorylation; Polymerase Chain Reaction; Polymorphism, Genetic; Precipitin Tests; Psychiatric Status Rating Scales; Schizophrenia; Sequence Analysis, Protein; Serine; Synapsins | 2004 |
The interface of a membrane-spanning leucine zipper mapped by asparagine-scanning mutagenesis.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Leucine; Leucine Zippers; Membrane Proteins; Molecular Sequence Data; Mutagenesis | 2004 |
Communication of stabilizing energy between substructures of a protein.
Topics: Amino Acid Substitution; Asparagine; Cytochromes c; Enzyme Stability; Genetic Variation; Guanidine; Hydrogen-Ion Concentration; Isoenzymes; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Saccharomyces cerevisiae Proteins; Temperature; Thermodynamics | 2005 |
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
Topics: Alanine; Amino Acid Motifs; Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Cell Membrane; Cell Separation; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Flow Cytometry; Hydrogen Bonding; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Thyrotropin; Rhodopsin; Software; Static Electricity; Threonine; Transfection | 2005 |
Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.
Topics: Alleles; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Isoleucine; Leucine; Neoplasm Proteins; Polymorphism, Single Nucleotide; Transfection; Tyrosine | 2005 |
Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex.
Topics: Animals; Antigens, CD; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; DNA Mutational Analysis; Galactosylceramides; Glycolipids; Humans; Lactosylceramides; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Point Mutation; Protein Binding; Recombinant Fusion Proteins; Swine; Time Factors; Tryptophan | 2005 |
Single mutations at Asn295 and Leu305 in the cytoplasmic half of transmembrane alpha-helix domain 7 of the AT1 receptor induce promiscuous agonist specificity for angiotensin II fragments: a pseudo-constitutive activity.
Topics: Angiotensin II; Animals; Asparagine; Chlorocebus aethiops; COS Cells; Cytoplasm; Humans; Leucine; Membrane Proteins; Mutation; Peptide Fragments; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 1 | 2005 |
The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor.
Topics: Amino Acid Motifs; Arginine; Asparagine; Binding Sites; Cell Line; Cell Membrane; Chorionic Gonadotropin; Crystallography, X-Ray; Cyclic AMP; Cytosol; DNA, Complementary; Heterozygote; Humans; Hydrogen Bonding; Leucine; Models, Molecular; Mutagenesis; Mutation; Phenotype; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, LH; Rhodopsin; Salts; Software | 2005 |
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blotting, Western; Carbachol; Cell Membrane; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dose-Response Relationship, Drug; Kinetics; Leucine; Ligands; Luciferases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Phosphatidylinositols; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, Muscarinic; Serine; Transfection | 2005 |
Interaction of glucokinase with the liver regulatory protein is conferred by leucine-asparagine motifs of the enzyme.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Carrier Proteins; Chlorocebus aethiops; Consensus Sequence; COS Cells; Glucokinase; Green Fluorescent Proteins; Hepatocytes; Humans; Kinetics; Leucine; Microscopy, Fluorescence; Models, Molecular; Mutagenesis, Site-Directed; Peptide Library; Rats; Rats, Wistar; Recombinant Fusion Proteins; Recombinant Proteins; Structure-Activity Relationship; Transfection; Two-Hybrid System Techniques | 2005 |
Molecular dynamics studies of the archaeal translocon.
Topics: Alanine; Archaea; Archaeal Proteins; Asparagine; Biophysics; Computer Simulation; Cytoplasm; Databases, Protein; Dimerization; Glycine; Histidine; Hydrogen; Ions; Leucine; Lipid Bilayers; Lipids; Methanococcus; Models, Molecular; Molecular Conformation; Oligopeptides; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Reproducibility of Results; Static Electricity; Time Factors; Water | 2006 |
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2006 |
The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells.
Topics: Amino Acid Motifs; Animals; Asparagine; CHO Cells; Cricetinae; Cricetulus; Female; Gene Expression Regulation; Glycine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Leucine; Metaphase; Mitosis; Spindle Apparatus | 2006 |
Identification of mutations in UBIAD1 following exclusion of coding mutations in the chromosome 1p36 locus for Schnyder crystalline corneal dystrophy.
Topics: Amino Acid Substitution; Asparagine; Corneal Dystrophies, Hereditary; Dimethylallyltranstransferase; Female; Humans; Leucine; Male; Mutation; Mutation, Missense; Polymorphism, Single Nucleotide; Proteins; Serine; Valine | 2007 |
Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy.
Topics: Aged; Asparagine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Italy; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2008 |
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Topics: Acetylcholinesterase; Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutamine; Isoleucine; Leucine; Mice; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Stereoisomerism; Terbutaline; Tyrosine | 2008 |
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders.
Topics: Aged; Asparagine; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Leucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Risk Factors; Serine | 2008 |
Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians.
Topics: Adult; Asparagine; Brazil; Female; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2009 |
Energy difference space random walk to achieve fast free energy calculations.
Topics: Algorithms; Asparagine; Chemistry, Physical; Computer Simulation; Entropy; Ethane; Leucine; Methanol; Models, Chemical; Models, Molecular; Models, Statistical; Normal Distribution; Probability; Random Allocation; Thermodynamics | 2008 |
Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Larva; Leucine; Ligands; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, AMPA; Sequence Deletion; Threonine; Xenopus | 2008 |
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan | 2008 |
Human caspase-3 inhibition by Z-tLeu-Asp-H: tLeu(P2) counterbalances Asp(P4) and Glu(P3) specific inhibitor truncation.
Topics: Amino Acid Sequence; Apoptosis; Asparagine; Caspase Inhibitors; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Dipeptides; Glutamic Acid; Humans; Leucine; Molecular Structure | 2008 |
Mutations Leu427, Asn428, and Leu431 residues within transmembrane domain-I-segment 6 attenuate ginsenoside-mediated L-type Ca(2+) channel current inhibitions.
Topics: Amino Acid Substitution; Animals; Asparagine; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Female; Ginsenosides; Ion Channel Gating; Leucine; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Xenopus laevis | 2009 |
Effect of active-site mutation at Asn67 on the proton transfer mechanism of human carbonic anhydrase II.
Topics: Asparagine; Carbonic Anhydrase II; Catalytic Domain; Crystallography, X-Ray; Deuterium Exchange Measurement; Enzyme Stability; Histidine; Humans; Kinetics; Leucine; Mutagenesis, Site-Directed; Proton-Motive Force; Thermodynamics; Water | 2009 |
Multi-wavelength light emitting diode array as an excitation source for light emitting diode-induced fluorescence detection in capillary electrophoresis.
Topics: Asparagine; Electrophoresis, Capillary; Epinephrine; Equipment Design; Fiber Optic Technology; Fluorescence; Fluorescent Dyes; Leucine; Limit of Detection | 2010 |
An αIIb mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the β-propeller (Asn2Asp) disrupts a calcium binding site in blade 6.
Topics: Adolescent; Amino Acid Sequence; Animals; Arabs; Asparagine; Aspartic Acid; Binding Sites; Blood Platelets; Calcium; Cell Line; Child; Child, Preschool; Cricetinae; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glutamine; Hemostasis; Heredity; Humans; Hydrogen Bonding; Integrin alpha2; Integrin beta3; Israel; Leucine; Male; Models, Molecular; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Thrombasthenia; Transfection | 2011 |
LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis.
Topics: Animals; Asparagine; Cell Differentiation; Cell Division; Cell Lineage; Coturnix; Dermis; Electroporation; Epithelium; Gene Expression Regulation, Developmental; Glycine; Leucine; Mitosis; Morphogenesis; Muscle Cells; Muscles; Somites; Transfection | 2011 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Selective cleavage of pepsin by molybdenum metallopeptidase.
Topics: Animals; Asparagine; Hot Temperature; Leucine; Metalloproteases; Molybdenum; Pepsin A; Peptide Fragments; Protein Conformation; Sequence Analysis, Protein; Swine; Tyrosine | 2012 |
Binding interactions with the complementary subunit of nicotinic receptors.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Female; Humans; Hydrogen Bonding; Leucine; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Nicotine; Oocytes; Patch-Clamp Techniques; Protein Binding; Pyridines; Receptors, Nicotinic; Sequence Homology, Amino Acid; Xenopus laevis | 2013 |
A C-terminal di-leucine motif controls plasma membrane expression of PMCA4b.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Calcium; Cell Compartmentation; Cell Count; Cell Membrane; Dogs; Dynamins; Endocytosis; Endosomes; Green Fluorescent Proteins; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Isoenzymes; Leucine; Lysine; Madin Darby Canine Kidney Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasma Membrane Calcium-Transporting ATPases; Protein Sorting Signals; Protein Transport; Sequence Alignment; Structure-Activity Relationship; Subcellular Fractions | 2013 |
Novel complex disease allele mutations in cleidocranial dysplasia patients.
Topics: Adenine; Alleles; Amino Acid Sequence; Asparagine; Aspartic Acid; Case-Control Studies; Cleidocranial Dysplasia; Conserved Sequence; Core Binding Factor Alpha 1 Subunit; Cytosine; Exons; Female; Guanine; Humans; Leucine; Male; Mutation, Missense; Proline; Protein Conformation; Thymine; Tooth, Supernumerary | 2014 |
S-Isovaline Contained in Meteorites, Induces Enantiomeric Excess in D,L-glutamic Acid During Recrystallization.
Topics: Asparagine; Chromatography, High Pressure Liquid; Crystallization; Evolution, Chemical; Glutamic Acid; Leucine; Meteoroids; Nitro Compounds; Stereoisomerism; Valine | 2015 |
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water | 2015 |
Synthesis, antimicrobial and antifungal possessions of tramadol esters: In vitro studies.
Topics: Anti-Bacterial Agents; Antifungal Agents; Asparagine; Esters; Leucine; Magnetic Resonance Spectroscopy; Tramadol | 2015 |
Serum metabolomic profile of incident diabetes.
Topics: Amino Acids, Branched-Chain; Asparagine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Erythritol; Female; Glucose; Humans; Isoleucine; Lactic Acid; Leucine; Male; Maryland; Metabolome; Middle Aged; Minnesota; Mississippi; North Carolina; Prospective Studies; Risk Factors; Trehalose; Valine | 2018 |
Bilirubin Interference in Plasma Amino Acid Analysis by Ion Exchange Chromatography.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Bilirubin; Cellulose; Child, Preschool; Chromatography, Ion Exchange; Cross-Sectional Studies; Cystine; Female; Glycine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Tryptophan | 2018 |
A single amino acid substitution alters ClpS2 binding specificity.
Topics: Agrobacterium tumefaciens; Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Cell Surface Display Techniques; Gene Expression; Hydrogen Bonding; Leucine; Molecular Dynamics Simulation; Mutation; Peptide Hydrolases; Peptides; Phenylalanine; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Proteolysis; Recombinant Proteins; Saccharomyces cerevisiae | 2020 |
Structural basis of ketamine action on human NMDA receptors.
Topics: Antidepressive Agents; Asparagine; Binding Sites; Cryoelectron Microscopy; Glutamic Acid; Glycine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ketamine; Leucine; Molecular Dynamics Simulation; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate | 2021 |
Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.
Topics: Animals; Asparagine; Bacterial Proteins; Borrelia burgdorferi; Leucine; Lyme Disease; Mice; Peptide Hydrolases; Proteolysis; Virulence; Virulence Factors | 2022 |
Mutation of Methionine to Asparagine but Not Leucine in Parathyroid Hormone Mimics the Loss of Biological Function upon Oxidation.
Topics: Asparagine; Humans; Leucine; Methionine; Mutation; Parathyroid Hormone; Peptides; Racemethionine; Sulfoxides | 2022 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Animal; Epilepsy; Glucose; Glutamates; Isoleucine; Ketone Bodies; Lactates; Leucine; Pentylenetetrazole; Pyruvates; Rats; Seizures; Succinates; Valine | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.
Topics: Amino Acid Sequence; Asparagine; Dictyostelium; Histidine; Isoleucine; Leucine; Leucine-Rich Repeat Proteins; Phenylalanine; Tryptophan; Tyrosine | 2022 |
L-Lysine supplementation affects dietary protein quality and growth and serum amino acid concentrations in rats.
Topics: Amino Acids; Animals; Asparagine; Carnitine; Caseins; Diet; Dietary Proteins; Dietary Supplements; Histidine; Leucine; Lysine; Male; Methionine; Ornithine; Racemethionine; Rats; Rats, Sprague-Dawley; Tryptophan; Valine; Weight Gain | 2023 |