asparagine has been researched along with glutamine in 990 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 450 (45.45) | 18.7374 |
| 1990's | 162 (16.36) | 18.2507 |
| 2000's | 206 (20.81) | 29.6817 |
| 2010's | 138 (13.94) | 24.3611 |
| 2020's | 34 (3.43) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Houpert, Y; Siest, G; Tarallo, P | 1 |
| Banks, GT; Bascomb, S; Bettelheim, KA; Fleming, A; Skarstedt, MT | 1 |
| Halsall, DM | 1 |
| Cooney, DA; Homan, ER; Jayaram, HN; Milman, HA; Rosenbluth, RJ | 1 |
| Cooney, DA; Geran, RI; Homan, ER; Jayaram, HN; Milman, HA; Pittillo, R; Rosenbluth, RJ; Ryan, J | 1 |
| Badr El-Din, SM; Foda, MS | 1 |
| Lev, M; Milford, AF | 1 |
| Conti, SF; LaMarre, AG; Straley, SC | 1 |
| Bono, VH; Cable, RG; Cooney, DA; Dion, RL; Milman, HA | 1 |
| Herbert, RA; Pfennig, N; Siefert, E | 1 |
| Davidson, L; Kitto, GB; Mason, M; Smith, G; Thiet, TQ | 1 |
| Galaev, IuV; Kulikova, AI | 1 |
| Cooney, DA; Milman, HA; Ward, JM | 1 |
| Bocker, H; Gräfe, U; Thrum, H | 1 |
| Beaugé, F; Mangeney, M; Nordmann, J; Nordmann, R | 1 |
| Hofmann, T; Parr, DM | 1 |
| Bain, B | 1 |
| Baron, AJ; Kavanagh, JP; Lovett, MG; Wootton, JC | 1 |
| Tritz, GJ; Williams, MV | 1 |
| Hung, W; Tourian, A | 1 |
| Bagaglio, JF; Mokotoff, M; Parikh, BS | 1 |
| Colosi, NW; Harper, AE; Tews, JK | 1 |
| Lee, SG; Lipmann, F | 1 |
| Balcar, VJ; Johnston, GA | 1 |
| Lea, PJ; Miflin, BJ | 1 |
| Canellakis, ES; Chen, KY | 1 |
| Matinian, KS; Umanskiĭ, SR | 1 |
| Blumenthal, KM; Smith, EL | 1 |
| Benuck, M; Lajtha, A | 1 |
| Görög, S; Kisfaludy, L; Renyei, M; Schön, I | 1 |
| Bagaglio, JF; Brynes, S; Mokotoff, M | 1 |
| Glass, J; Pelzig, M | 1 |
| Spiers, AS; Wade, HE | 2 |
| Chinchar, GD; Sinclair, JH | 1 |
| Smith, GG; Williams, KM | 1 |
| Arimura, GK; Wu, MC; Yunis, AA | 1 |
| Borella, LD; Camitta, BM; Holcenberg, JS; Ring, BJ | 1 |
| McKerrow, JH | 1 |
| Gibson, KJ; Ordal, GW; Villani, DP | 1 |
| Jones, RA | 1 |
| Aharonowitz, Y; Demain, AL | 1 |
| Katz, J; Okajima, F | 1 |
| Abuchowski, A; Davis, FF; McCoy, JR; Palczuk, NC; van Es, T | 1 |
| Hornsperger, JM; McCann, PP; Seiler, N | 1 |
| Abuchowski, A; Kafkewitz, D; Radcliffe, CW | 1 |
| Bhuyan, BK; Douros, JD; Hanka, LJ; Martin, DG; Neil, GL | 1 |
| Coit, R; Magno, M; Woolley, PV | 1 |
| Rimpler, M; Robinson, DV | 1 |
| Hossmann, KA; Kawakami, S; Kleihues, P; Kobayashi, K | 1 |
| Brubaker, RR; Dreyfus, LA | 1 |
| Rabinovitz, M; Rabon, A; Vistica, DT | 1 |
| Rumen, NM | 1 |
| Neilson, AH; Nordlund, S | 1 |
| Rognstad, R | 1 |
| Karasawa, Y | 1 |
| Davy, KW; Morrris, CJ | 1 |
| Gilchrist, AJ; Juniper, BE; Robins, RJ | 1 |
| Walli, AK | 1 |
| Tschesche, H | 1 |
| Mantle, PG; Nisbet, LJ | 1 |
| Dickinson, HR; Flouret, G; Kopple, KD; Nakagawa, SH | 1 |
| Chrambach, A; Rumen, NM | 1 |
| Iboian, SR; Tatevosian, EM | 1 |
| Jarrett, IG; Lindsay, DB; Linzell, JL; Mangan, JL | 1 |
| Richheimer, SL; Robinson, AB | 1 |
| Aledort, L; Patel, I; Puszkin, EG | 1 |
| Albrecht, AM; Biedler, JL; Hutchison, DJ; Spengler, BA; Stockert, E | 1 |
| Golden, S; Katz, J; Wals, PA | 1 |
| Airoldi, LP; Doonan, S | 1 |
| Dolowy, WC; Holcenberg, JS; Tang, E | 1 |
| Ferguson, DA; Marucci, AA; Phillips, AW | 1 |
| Chaskes, S; Tyndall, RL | 1 |
| Trayhurn, P | 1 |
| Fillios, LC; Frankel, DL; Newburg, DS | 1 |
| Murthy, MR; Roux, H | 2 |
| Murthy, MR; Roux, H; Thénot, JP | 2 |
| Black, JA; Harkins, RN; Stenzel, P | 1 |
| Váradi, A | 1 |
| Rando, RR | 1 |
| Chellemi, F | 1 |
| Aseeva, KB; Evstigneeva, ZG; Kretovich, VL; Martynova, EM | 1 |
| Folbergrová, J; Norberg, K; Quistorff, B; Siesjö, BK | 1 |
| Spaeth, AE; Windmueller, HG | 1 |
| Desiderio, DM; Young, MA | 1 |
| Nau, H | 1 |
| Gross, S; Maskaleris, ML | 1 |
| Akiyama, Y; Asai, S; Kitoh, T; Kubota, M; Mikawa, H | 1 |
| Rupitz, K; Trimbur, D; Warren, RA; Withers, SG | 1 |
| Rideau, N; Simon, J | 1 |
| Fiechter, A; Kurano, N; Kurano, S; Leist, C; Messi, F | 1 |
| Baines, AJ; Bull, AT; Curling, EM; Hayter, PM; Jenkins, N; Salmon, I; Strange, PG | 1 |
| García, JL; García, P; Sanz, JM | 1 |
| Boone, T; Delorme, E; Elliott, S; Giffin, J; Jacobsen, F; Lorenzini, T; Martin, F | 1 |
| Acosta, GB; Losada, ME | 1 |
| Heyn, MP; Khorana, HG; Marti, T; Otto, H; Rösselet, SJ | 1 |
| Flint, HJ; Zhang, JX | 1 |
| Huber, R; Plückthun, A; Steipe, B | 1 |
| Brown, WV; Coleman, T; Faustinella, F; Goldberg, IJ; Hide, WA; Ishimura-Oka, K; Oka, K; Semenkovich, CF; Shachter, N; Smith, LC | 1 |
| Wright, HT | 2 |
| Chan, WY; Hill, PS; Hruby, VJ | 1 |
| Coruzzi, GM; McGrath, RB | 1 |
| Buczko, E; Dufau, ML; Kitamura, M; Tsai-Morris, CH; Zhang, R | 1 |
| Salloum, RM; Souba, WW; Stevens, BR | 1 |
| Betlach, MC; Kliger, DS; Miercke, LJ; Milder, SJ; Shand, RF; Stroud, RM; Thorgeirsson, TE | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Robinson, AB; Robinson, LR | 1 |
| Meunier, JC; Nury, S | 1 |
| Chen, MW; Ishino, Y; Jahn, D; Kim, YC; Söll, D | 1 |
| Nathans, J | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Kilberg, MS; Tamarappoo, BK | 1 |
| Chazenbalk, GD; Nagayama, Y; Rapoport, B; Russo, D; Wadsworth, HL | 1 |
| Chiu, L; Erecińska, M; Nelson, D; Zaleska, MM | 1 |
| Lingrel, JB; Price, EM; Rice, DA | 1 |
| Conradt, HS; Nimtz, M; Noll, G; Pâques, EP | 1 |
| Baquet, A; Hue, L; Meijer, AJ; Plomp, PJ; van Woerkom, GM | 1 |
| Aggarwal, AK; Beamer, LJ; Harrison, SC; Jordan, SR; Obeysekare, UR; Pabo, CO | 1 |
| Breipohl, G; Knolle, J; Stüber, W | 1 |
| Albericio, F; Barany, G; van Abel, R | 1 |
| Blacher, RW; Glazer, AN; Klotz, AV; Thomas, BA | 1 |
| Cox, GB; Gibson, F; Howitt, SM | 1 |
| Abumurad, N; Ghishan, FK; Nylander, W; Redha, R; Said, HM; Van Voorhis, K | 1 |
| Abumrad, NN; Ghishan, FK; Said, HM; Van Voorhis, K | 1 |
| Bennett, JL; Chen, GZ; Foster, LA; Pax, RA; VandeWaa, EA | 1 |
| Ennis, HL; Giorda, R; Ohmachi, T; Richter, H; Shaw, DR | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE | 1 |
| Clarke, DM; Inesi, G; Leberer, E; Loo, TW; MacLennan, DH; Maruyama, K | 1 |
| Cole, DE; Holcenberg, JS; Jolivet, J; Poplack, DG | 1 |
| Boghossian, JO; Pettit, FH; Shive, W | 1 |
| Harris, GW; Howlin, B; Moss, DS | 1 |
| Aleshin, OI; Baranov, AV; Nikolaeva, LF; Pavlov, NA; Pisarenko, OI; Pomerantsev, EA; Savchenko, AP; Studneva, IM | 1 |
| Natori, Y; Okada, M; Oshima, M; Shibata, S; Shindo, N | 1 |
| Kimura, H | 1 |
| Arst, HN; Grenson, M; Wiame, JM | 1 |
| Joy, K; Ta, TC | 1 |
| Fang, GH; Hager, LP; Kenigsberg, P | 1 |
| Yan, SB | 1 |
| Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE | 1 |
| Aronson, AI; Strauch, MA; Zalkin, H | 1 |
| Bowen, DM; Esiri, MM; Francis, PT; Hunt, A; Lowe, SL; Najlerahim, A; Palmer, AM; Patel, AJ; Procter, AW; Stratmann, GC | 1 |
| Chance, WT; Enrione, EB; Popp, MB; Wagner, SC | 1 |
| Barrett, J; Grantham, BD | 1 |
| Grinde, B | 1 |
| Arata, Y; Nishihara, S; Shimizu, A | 1 |
| Burley, SK; Petsko, GA | 1 |
| Klibanov, AM; Tomazic, SJ | 2 |
| Kossiakoff, AA | 1 |
| Sheares, BT | 1 |
| Chaves Das Neves, HJ; Vasconcelos, AM | 1 |
| Brkljac, O; Kovacević, Z; Lelas, S; Popović, J | 1 |
| Cole, DE; Holcenberg, JS; Jolivet, J; Lavi, LE | 1 |
| Gracy, RW; Yüksel, KU | 1 |
| Imoto, T; Kuroki, R; Moriyama, T; Yamada, H | 1 |
| Golan-Goldhirsh, A | 1 |
| Alpar, HO; Lewis, DA | 1 |
| Fujita, S; Sasada, Y; Takenaka, A | 1 |
| Carter, P; Fersht, AR; Lowe, DM; Wilkinson, AJ; Winter, G | 1 |
| Iwainsky, H; Sehrt, I | 4 |
| Mircevová, L; Mokrý, Z; Simonová, A | 1 |
| Gerstenbrand, F; Gründig, E; Schedl, R; Simanyi, M; Weiss, H | 1 |
| Dubois, E; Grenson, M; Wiame, JM | 1 |
| Fischbach, R; Harrer, G | 1 |
| Hersh, EM | 1 |
| van de Poll, KW | 1 |
| Dougall, DK | 1 |
| Fowler, MW; Jessup, W; Sarkissian, GS | 1 |
| Folbergrová, J; Ljunggren, B; Norberg, K; Siesjö, BK | 1 |
| Pliskowá, M | 1 |
| Mehta, JM; Prager, MD | 1 |
| Hill, JM; Khan, A | 1 |
| Benuck, M; Lajtha, A; Stern, F | 3 |
| Veerkamp, JH | 1 |
| Cohen, L; Eagle, H; Levy, M; Washington, CL | 1 |
| Orr, GR; Patterson, MK | 1 |
| Fontenelle, LJ; Henderson, JF | 1 |
| Haguenau, F; Michelson-Fiske, S; Rabotti, GF | 1 |
| Knox, WE; Kupchik, HZ | 1 |
| Cooney, D; Davis, R; Van Atta, G | 1 |
| Nahorski, SR | 1 |
| Cappugi, G; Nassi, P; Ramponi, G; Treves, C | 1 |
| Chou, TC; Handschumacher, RE | 1 |
| Bohnert, JL; Taniuchi, H | 1 |
| Bajusz, S; Barát, E; Cseh, G; Gráf, L; Patthy, A | 1 |
| Buchanan, JM | 1 |
| Holmquist, R; Jukes, TH | 1 |
| Hogan, BL; Murden, S | 1 |
| Robinson, AB; Rudd, CJ | 1 |
| Folkes, BF | 1 |
| Langer, BW; Smith, WJ; Theodorides, VJ | 1 |
| Suzuki, N; Tucker, D | 1 |
| Dautrevaux, M; Ducastaing, S; Han, KK; Hombrados, I; Neuzil, E; Plancot, MT; Tetaert, D | 1 |
| Iijima, T; Sato, T | 1 |
| Martin, DW; Murphy, B | 1 |
| Hellebust, JA; Liu, MS | 1 |
| Pogorelova, TN | 1 |
| Kaback, HR; Tucker, AN; White, DC | 1 |
| Erler, W; Feist, H; Flossmann, KD; Höfer, M | 1 |
| Borgström, B; Erlanson, C; Sternby, B | 1 |
| Vestermark, A | 1 |
| Batra, KV; Dolowy, WC; Holcenberg, JS; Roberts, J; Schrek, R | 1 |
| Robinson, AB | 1 |
| Benezra, D; Birkenfeld, V; Hochman, A; Pitaro, R | 1 |
| Tepper, BS; Varma, KG | 1 |
| Kreil, G | 1 |
| Anderson, PM; Meister, A; Wellner, VP | 1 |
| Yamamoto, M; Young, JL | 1 |
| Lewis, SD; Shafer, JA | 1 |
| Hooghe-Peters, EL | 1 |
| Novak, EK; Phillips, AW | 1 |
| Willis, RC; Woolfolk, CA | 1 |
| Halpern, YS | 1 |
| Doudoroff, M; Neilson, AH | 1 |
| Anderson, PJ; Gibson, D | 1 |
| Bittner, J | 1 |
| Benson, JV | 1 |
| Ali, A; Faesel, JH; Sarantakis, D; Stevenson, D; Weinstein, B | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Büchner, M; Hofmann, F; Scheid, P | 1 |
| Bentyn, K; Choroszewska, A; Jaszczak, S | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Bertolini, AM; Santagostino, A | 1 |
| Kihara, T; Kurimoto, K; Shimada, M; Watanabe, M | 1 |
| Karasawa, Y; Shibata, F; Tasaki, I; Yokota, HO | 1 |
| Cohen, HP; Lin, S | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Kopple, JD; Shinaberger, JH; Swendseid, ME; Umezawa, CY | 1 |
| Bradenberger, H; Hediger, H; Schmid, K; Stevens, L | 1 |
| Gurd, FR; Keim, P; Marshall, RC; Morrow, JS; Vigna, RA | 1 |
| Manchester, KL; Turner, LV | 1 |
| Chibata, I; Ito, H; Kishi, T | 1 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| McKerrow, JH; Robinson, AB; Scotchler, JW | 1 |
| Einarsson, M; Joner, PE; Kristiansen, T | 1 |
| Berezov, TT; Evseev, LP; Khisamov, GZ; Zanin, VA | 1 |
| Paquin, R | 1 |
| Dolowy, WC; Fitzmaurice, MA; Holcenberg, JS; Riley, V; Roberts, J; Spackman, D | 1 |
| Applegarth, DA; Hardwick, DF; Hingston, J; Ingram, P | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Goodman, D; Kafkewitz, D | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Broome, JD | 2 |
| Bachynsky, N; Prager, MD | 1 |
| Holcenberg, JS | 2 |
| Balis, ME; Miller, HK | 1 |
| Meister, A | 2 |
| Berk, B; Robison, RS | 1 |
| Bertino, JR; Capizzi, RL; Handschumacher, RE | 1 |
| Dolowy, WC; Holcenberg, JS; Roberts, J | 1 |
| Bobbitt, JL; Boeck, LD; Burck, PJ; Frank, BH; Grinnan, EL; Ho, PP; Milikin, EB; Squires, RW | 1 |
| Gallmeier, WM; Göbel, FW; Hartung, W; Schmidt, CG | 1 |
| Milner, L; Prusiner, S | 1 |
| Dworak, JE; Ryan, WL | 1 |
| Hayashida, H; Kikuchi, M; Nakano, E; Sakaguchi, K | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Hardman, JK; Myers, JS | 1 |
| Bauer, S; Kirchner, H | 1 |
| Balis, ME | 1 |
| Gross, R; Hirschmann, WD; Oerkermann, H | 1 |
| Canellos, GP; Haskell, CM | 2 |
| Freese, E; Wax, R | 1 |
| Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
| Wilcox, M | 1 |
| Holden, JT; Reid, KG; Utech, NM | 1 |
| Belasco, IJ | 1 |
| Boucher, ME; Bromer, WW; Frank, BH; Patterson, JM; Pekar, AH | 1 |
| Carmo, RJ; Leao, AA | 1 |
| Buttery, PJ | 1 |
| Asmar, JA; Daghir, NJ; Sifri, M | 1 |
| Horowitz, B; Meister, A | 1 |
| Fidler, IJ; Montgomery, PC | 1 |
| Casola, L; Di Matteo, G | 1 |
| Etheredge, EE; Najarian, JS; Shons, AR | 1 |
| Cannizzaro, G; La Grutta, V; Palazzoadriano, M | 1 |
| Kedenburg, CP | 1 |
| Gross, W; Ring, K | 1 |
| Meister, A; Ubuka, T | 1 |
| Parekh, LJ; Ramakrishnan, CV; Sakariah, KK | 1 |
| Maigret, B; Perahia, D; Pullman, B | 1 |
| Cavallo, P; Marshall, GR; Pietta, PG | 1 |
| Brinster, RL | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Chang, AY; Clark, JM; Reichmann, ME; Spiegelman, S | 1 |
| Jones, OW; Nirenberg, MW | 1 |
| Cannizzaro, G; Giammanco, S; La Grutta, V; Palazzoadriano, M | 1 |
| Nunn, PB; Vega, A | 1 |
| Chudnovskaia, MV; Matveev, MP; Sukhanberdina, FKh | 1 |
| Sergeeva, SA | 1 |
| Aledort, L; Puszkin, E; Puszkin, S | 2 |
| Bjarnason, J; Carpenter, KJ | 1 |
| Nakamura, T; Okami, Y; Seki, Y | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Hirs, CH; Jackson, RL | 1 |
| Lichtenstein, N; Lustig, N; Spiegelstein-Klarfeld, H | 1 |
| Elliott, KA; Yoshino, Y | 1 |
| Wilke, J | 1 |
| Garg, GK; Virupaksha, TK | 1 |
| Bennett, C; Edelman, GM; Konigsberg, WH | 1 |
| Melcher, G | 1 |
| Atkin, GE; Ferdinand, W | 1 |
| Brunfeldt, K; Halstrom, J; Kovács, K; Schou, O | 1 |
| Golovach, VM; Ratich, IB | 1 |
| Balis, ME; Krakoff, IH; Miller, HK; Salser, JS | 1 |
| Sinex, FM | 1 |
| Astaldi, A; Astaldi, G; Burgio, GR; Krc, I; Micu, D | 1 |
| Geppert, E; Hinzen, DH; Isselhard, W; Mäurer, W | 1 |
| Chung, WP; Smith, DB | 1 |
| Derr, I; Prager, MD | 1 |
| Delaunay, J; Maleknia, N; Schapira, G | 1 |
| Tower, DB; Wherrett, JR | 1 |
| Wender, M; Wróblewski, T; Zgorzalewicz, B | 1 |
| Paganou, A; Taylor-Papadimitriou, J; Yovanidis, C; Zervas, L | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Ariely, S; Patchornik, A; Wilchek, M | 1 |
| Flatmark, T; Sletten, K | 1 |
| Berridge, BJ; Cummings, JG; Lin, SC; Peters, JH | 1 |
| Jardetzky, O; Markley, JL; Putter, I | 1 |
| Orlova, NV | 1 |
| Bjarnason, J; Steglich, W; Weygand, F | 1 |
| Bodnaryk, RP; Levenbook, L | 1 |
| Schneider, G | 1 |
| Dietel, K; Schmöger, R | 1 |
| Cannizzaro, G; Gianguzza, M; Palazzoadriano, M | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Balis, ME; Miller, HK; Salser, JS | 1 |
| Berridge, BJ; Chao, WR; Cummings, JG; Lin, SC; Peters, JH | 1 |
| Hirsch, W; Mex, A; Vogel, F | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Naylor, AW; O'Neal, TD | 1 |
| Pearse, WH; Sornson, H | 1 |
| Harada, K | 2 |
| Cantor, F; Kupfer, S; Oreskes, I | 1 |
| De la Llosa, P; Jutisz, M; Tertrin, C | 1 |
| Kleczkowski, K | 1 |
| Benton, DA; Breuer, LH; Loosli, JK; Warner, RG | 1 |
| Carpenter, FH; Slobin, LI | 1 |
| Henderlong, PR; Schmidt, RR | 1 |
| Munier, RL; Sarrazin, G | 1 |
| Neumann, PZ; Silverberg, M | 1 |
| Christian, JH; Waltho, JA | 1 |
| Hempel, K; Männl, HF | 1 |
| Anand, N; Dutta, AS; Kar, K | 1 |
| Tracey, MV | 1 |
| Loewy, AG; Matacić, S | 1 |
| Baxter, CF; Ortiz, CL | 1 |
| Blomquist, AT; Harpp, DN; Hiscock, BF | 1 |
| Hentschel, G; Kull, U | 1 |
| Orlova, NV; Smolenskaia, NM | 1 |
| Andreeva, LA | 1 |
| Neumann, PZ; Sass-Kortsak, A | 1 |
| Alburn, HE; Grant, NH | 1 |
| Jones, HE; Park, RW | 1 |
| Alexander, NM; Klatskin, G; Scheig, R | 1 |
| Krishnaswamy, PR; Ramakrishna, M | 1 |
| Hubbard, JS; Stadtman, ER | 1 |
| Nozaki, Y; Tanford, C | 2 |
| Orr, G; Patterson, MK | 1 |
| Ochs, RS | 1 |
| Barbeau, A; Butterworth, RF; Giguere, F; Hamel, E; Landreville, F; Merkel, A | 1 |
| Coleman, PS; Lavietes, BB | 2 |
| Mangano, RM; Schwarcz, R | 1 |
| Berezov, TT | 1 |
| Magasanik, B; Reitzer, LJ | 1 |
| Boland, MJ; Farnden, KJ; Mc Cormack, DK | 1 |
| Applebaum, FR; Dennis, MB; Detter, JC; Holcenberg, JS; Newman, ML; Rastelli, LN; Schmer, G | 1 |
| Moraga, DA; Schuster, SM; Unnithan, S | 1 |
| Foda, MS; Hashem, SA; Zedan, HH | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Balling, R; Coon, C | 1 |
| Bendich, A; Kafkewitz, D | 2 |
| Abuchowski, A; Bendich, A; Davis, FF; Kafkewitz, D | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Welsh, M | 1 |
| Hayashi, S; Kawanaka, M; Ohtomo, H | 1 |
| Bassett, JM; Burks, AH; Madill, D; Pinches, RA | 1 |
| Benjamin, AM; Quastel, JH; Verjee, ZH | 1 |
| Wold, F | 1 |
| Coyle, JT; Ferkany, JW | 1 |
| Johnson, P; Soby, LM | 1 |
| Dubois, E; Grenson, M | 1 |
| Baker, GL; Filer, LJ; Stegink, LD | 1 |
| Kiyama, S; Makita, M; Watanabe, Y; Yamamoto, S | 1 |
| Herbert, RA; Macfarlane, GT | 1 |
| Roberts, J; Rosenfeld, H | 1 |
| Holcenberg, JS; Kien, CL | 1 |
| Grinde, B; Seglen, PO | 1 |
| Barral-Alix, I; Jean, G; Nordmann, J; Nordmann, R; Petit, MA | 1 |
| Manchester, KL; Tyobeka, EM | 1 |
| Christensen, HN; Handlogten, ME; Kilberg, MS | 1 |
| Gordon, PB; Poli, A; Seglen, PO | 1 |
| Churchill, RD; Evans, G; Gaitonde, MK | 1 |
| Porteous, JW | 1 |
| McDonald, IK; Thornton, JM | 1 |
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| Curukovic, A; DeBerardinis, RJ; Huerta-Rosario, M; Jeong, MH; Jewell, JL; Lama-Sherpa, TD; Lewis, C; Melick, CH; Meng, D; Tiwary, S; Urquhart, G; Wang, H; Yang, Q; Zacharias, LG | 1 |
| Li, W; Peng, Y; Yang, Y; Zhang, N; Zheng, J; Zhou, S | 1 |
| Bakkali, A; Brigitha, LJ; Pieters, R; Struys, EA; van der Sluis, IM | 1 |
| Li, R; Shi, W; Yan, Z; Yao, L | 1 |
| Li, B; Luo, P; Wu, J; Xian, Y; Xiao, R; Zhang, Y | 1 |
| Almeida, MR; Bento, HBS; Carvalho, PJ; Paiva, GB; Pedrolli, DB; Santos-Ebinuma, VC; Silva, CG; Tavares, APM | 1 |
| Birkou, M; Delegkou, GN; Episkopou, V; Fragkaki, N; Marousis, KD; Spyroulias, GA; Toro, T | 1 |
| Chai, Y; Gong, J; Kai, J; Lin, J; Liu, J; Shu, X; Tang, M; Yang, J; Yang, X; Zhang, W; Zhang, X | 1 |
| Flaxman, HA; Ichikawa, S; Lloyd, HC; Pratt, MR; Shen, D; Vallavoju, N; Wang, B; Woo, CM; Xu, W | 1 |
| Bai, J; Chang, J; Shi, J; Sun, C; Tang, R; Wang, H; Zhang, Q; Zhou, K | 1 |
| Hanada, K; Itatani, Y; Kawada, K; Maekawa, H; Miyoshi, H; Nishikawa, G; Obama, K; Taketo, MM | 1 |
| Bachir, N; Haddarah, A; Pujola, M; Sepulcre, F | 1 |
| Baiocco, G; Guardamagna, I; Iaria, O; Ivaldi, GB; Liotta, M; Lonati, L; Maggi, M; Mentana, A; Pessino, G; Previtali, A; Scotti, C; Tabarelli de Fatis, P; Uggè, V | 1 |
| Bain, J; Colón-Emeric, C; Ilkayeva, O; Lee, RH; Muehlbauer, M; Pieper, C; Wixted, D | 1 |
| Brown, K; Huff-Lonergan, EJ; Johnson, LG; Lonergan, SM; N Nair, M; Prenni, JE; Zhai, C | 1 |
| Amirjannati, N; Bazrafkan, M; Gilany, K; Henkel, R; Hosseini, E; Moghadasfar, H | 1 |
| Anand, A; Behera, PK; Beura, S; Bobde, RC; Chakrapani, M; Chandana, M; Das, R; Dixit, A; Ghosh, S; Jain, V; Kundu, R; Mohanty, AK; Nagaraj, VA; Padmanaban, G; Prabhu, SR; Satyamoorthy, K; Suryawanshi, AR | 1 |
| Li, J; Sun, X; Yan, S | 1 |
| Cheung, KK; Chung, SF; Chung, WH; Kim, CF; Leung, YC; So, PK; Tam, SY; To, JC; Wong, KY | 1 |
47 review(s) available for asparagine and glutamine
| Article | Year |
|---|---|
Aminotransferase activity in brain.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartate Aminotransferases; Brain; Catalysis; Chemical Phenomena; Chemistry; Diet; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycine; Hormones; Humans; Isoenzymes; Ketoglutaric Acids; Ornithine; Rats; Serine; Swine; Transaminases; Tyrosine Transaminase | 1975 |
A critical evaluation of the application of amino acid racemization to geochronology and geothermometry.
Topics: Amino Acids; Asparagine; Bacteria; Bone and Bones; Chemical Phenomena; Chemistry; Chronology as Topic; Collagen; Fossils; Geological Phenomena; Geology; Glutamine; Hydrolysis; Isoleucine; Kinetics; Minerals; Paleontology; Seawater; Temperature; Tooth; Water | 1977 |
Non-enzymatic, post-translational, amino acid modifications in ageing. A brief review.
Topics: Aging; Amides; Amino Acids; Animals; Asparagine; Aspartic Acid; Glutamine; Half-Life; Isomerism; Models, Biological; Oligopeptides; Proteins; Rats; Structure-Activity Relationship | 1979 |
Nonenzymatic deamidation of asparaginyl and glutaminyl residues in proteins.
Topics: Amides; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Molecular Sequence Data; Protein Processing, Post-Translational | 1991 |
A gene network controlling glutamine and asparagine biosynthesis in plants.
Topics: Asparagine; Aspartate Aminotransferases; Aspartate-Ammonia Ligase; Gene Expression Regulation; Genes, Plant; Glutamate-Ammonia Ligase; Glutamine; Isoenzymes; Multigene Family; Plants | 1991 |
[Neurotransmitters and modulators in the cerebellum].
Topics: Animals; Asparagine; Cerebellum; Electrophysiology; Glutamine; Prostaglandins; Purkinje Cells; Synaptic Transmission | 1988 |
Nitrogen catabolite repression in yeasts and filamentous fungi.
Topics: Amino Acids; Ammonia; Asparagine; Aspergillus nidulans; Biological Transport; Fungi; Genes, Fungal; Glutamates; Glutamic Acid; Glutamine; Membrane Transport Proteins; Neurospora crassa; Nitrogen; Proline; Saccharomyces cerevisiae; Yeasts | 1985 |
Autophagy and lysosomal proteolysis in the liver.
Topics: Amino Acids; Animals; Asparagine; Calcium; Cyclic AMP; Epinephrine; Glucagon; Glucocorticoids; Glutamine; Hydrogen-Ion Concentration; Hydrolases; Insulin; Intermediate Filaments; Kynurenine; Liver; Lysosomes; Membranes; Models, Biological; Peptide Hydrolases; Phagocytosis; Thyroxine | 1985 |
The amidotransferases.
Topics: Anthranilate Synthase; Asparagine; Aspartic Acid; Binding Sites; Carbamates; Cytosine Nucleotides; Fructosephosphates; Glutamine; Ligases; Liver; Macromolecular Substances; NAD; Organophosphorus Compounds; Protein Conformation; Pyrimidine Nucleotides; Ribose; RNA, Transfer; Transaminases; Xanthines | 1973 |
Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
Topics: Aging; Amides; Amino Acid Sequence; Animals; Ascorbic Acid; Asparagine; Bacterial Proteins; Biological Evolution; Cytochrome c Group; Escherichia coli; Fructose-Bisphosphate Aldolase; Glutamine; Histones; Humans; Hydrogen-Ion Concentration; Hydrolysis; Muramidase; Oxygen; Peptides; Proteins; Temperature | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
On the synthesis and utilization of glutamine.
Topics: Adenosine Triphosphate; Asparagine; Glutamine; Ligases | 1969 |
L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma | 1970 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
Determination of glutamic and aspartic acids and their amides.
Topics: Aminobutyrates; Ammonia; Asparaginase; Asparagine; Aspartic Acid; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Colorimetry; Electrophoresis, Paper; Glutamate Dehydrogenase; Glutamates; Glutamine; Indicators and Reagents; L-Lactate Dehydrogenase; Leucyl Aminopeptidase; Lyases; Manometry; Methods; Papain; Pyruvates; Transaminases | 1971 |
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
[Asparagine biosynthesis and tumor growth].
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1982 |
Enzyme-induced asparagine and glutamine depletion and immune system function.
Topics: Ammonia; Animals; Asparaginase; Asparagine; Escherichia coli; Glutaminase; Glutamine; Humans; Immunosuppressive Agents; Leukemia; Lymphocytes; Polyethylene Glycols; Vibrio | 1983 |
The inhibition of lymphocyte mitogenesis by asparaginase: a still unexplained phenomenon.
Topics: Animals; Asparaginase; Asparagine; Cell Membrane; Cells, Cultured; Erwinia; Escherichia coli; Glutaminase; Glutamine; Glycoproteins; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Membrane Proteins; Mitosis; Models, Biological; Polyethylene Glycols; Vibrio | 1984 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Deamidation of asparagine and glutamine residues in proteins and peptides: structural determinants and analytical methodology.
Topics: Amino Acid Sequence; Animals; Asparagine; Glutamine; Humans; Molecular Sequence Data; Peptides; Proteins | 1994 |
[Molecular and catalytic properties of bacterial glutamin-(asparagin-)ase].
Topics: Amidohydrolases; Asparagine; Catalysis; Glutamine; Hot Temperature; Molecular Weight; Pseudomonas aeruginosa; Substrate Specificity | 1995 |
[Involvement of excitatory amino acids in the brain damage of neonatal asphyxia].
Topics: Animals; Asparagine; Asphyxia Neonatorum; Brain Damage, Chronic; Cell Death; Glutamine; Humans; Infant, Newborn; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Nonenzymatic deamidation of food proteins.
Topics: Amides; Ammonia; Asparagine; Food; Food Handling; Glutamine; Hydrogen-Ion Concentration; Maillard Reaction; Plant Proteins; Plants, Edible | 1996 |
Analytical techniques used to study the degradation of proteins and peptides: chemical instability.
Topics: Arginine; Asparagine; Chemistry Techniques, Analytical; Drug Stability; Glutamine; Hydrolysis; Peptides; Proteins; Reproducibility of Results | 1998 |
[Stimulating amino acids in epilepsy: possibilities of treatment].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Asparagine; Epilepsy; Female; Glutamine; Humans; Kainic Acid; Male; N-Methylaspartate; Synaptic Transmission | 2000 |
Metabolite and light regulation of metabolism in plants: lessons from the study of a single biochemical pathway.
Topics: Amino Acids, Dicarboxylic; Arabidopsis; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Carbon; Gene Expression Regulation, Plant; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Light; Nitrogen; Receptors, Glutamate | 2001 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
Steps towards an integrated view of nitrogen metabolism.
Topics: Amino Acid Oxidoreductases; Amino Acids; Asparagine; Cysteine; Gene Expression Regulation, Plant; Glutamate Dehydrogenase; Glutamine; Glycine; Ketoglutaric Acids; Malates; Nicotiana; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrogen; Oxidation-Reduction; Quaternary Ammonium Compounds; Serine; Signal Transduction | 2002 |
The mechanism of intein-mediated protein splicing: variations on a theme.
Topics: Alanine; Amino Acid Sequence; Asparagine; Conserved Sequence; Glutamine; Inteins; Models, Chemical; Protein Splicing | 2005 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
Aminoacyl-tRNA synthesis by pre-translational amino acid modification.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Archaea; Asparagine; Bacillus subtilis; Chlorophyll; Escherichia coli; Glutamine; Heme; Models, Biological; Phylogeny; Porphyrins; Protein Modification, Translational; RNA, Transfer, Amino Acyl; Species Specificity | 2004 |
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Cysteine; Glutamine; Nitrogenous Group Transferases; Phosphotransferases; RNA, Transfer, Amino Acyl; Selenocysteine | 2008 |
Assembly of the asparagine- and glutamine-rich yeast prions into protein fibrils.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Glutathione Peroxidase; Molecular Sequence Data; Peptide Termination Factors; Prions; Protein Conformation; Protein Folding; Saccharomyces cerevisiae Proteins; Yeasts | 2008 |
Expanding targets for a metabolic therapy of cancer: L-asparaginase.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
Asparaginase pharmacokinetics and implications of therapeutic drug monitoring.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Clinical Trials as Topic; Drug Monitoring; Enzyme Activation; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2015 |
ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases.
Topics: Amidohydrolases; Animals; Asparagine; Glutamine; Humans; Hyperammonemia; Neoplasms; Nitrogen; Sulfur | 2016 |
Self-generated covalent cross-links in the cell-surface adhesins of Gram-positive bacteria.
Topics: Adhesins, Bacterial; Asparagine; Aspartic Acid; Bacterial Adhesion; Fimbriae Proteins; Glutamine; Gram-Positive Bacteria; Lysine; Models, Molecular; Protein Conformation; Protein Folding; Protein Interaction Domains and Motifs; Protein Stability; Threonine | 2015 |
Improved Therapeutic Efficacy in Bone and Joint Disorders by Targeted Drug Delivery to Bone.
Topics: Asparagine; Binding Sites; Bone and Bones; Bone Diseases; Drug Delivery Systems; Drug Design; Durapatite; Enzymes; Estradiol; Glutamine; Humans; Hydrolysis; Joint Diseases; Levofloxacin; Oligopeptides; Protein Binding | 2016 |
Amino acid synthesis deficiencies.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Asparagine; Brain Diseases; Central Nervous System; Fetal Growth Retardation; Glutamine; High-Throughput Nucleotide Sequencing; Humans; Ichthyosis; Limb Deformities, Congenital; Metabolic Diseases; Mice; Microcephaly; Proline; Serine | 2017 |
CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors.
Topics: Amidohydrolases; Asparagine; Bacterial Toxins; Computational Biology; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Glutamine; Immunologic Factors; Neoplasms; rac1 GTP-Binding Protein; Virulence Factors | 2018 |
Isolation, Purification, Characterisation and Application of L-ASNase: A Review.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Glutamine; Humans; Neuroblastoma; Patents as Topic; Pectobacterium carotovorum | 2019 |
Modifications of recombinant monoclonal antibodies in vivo.
Topics: Animals; Antibodies, Monoclonal; Asparagine; Cysteine; Disulfides; Glutamine; Glycosylation; Humans; Lysine; Pharmaceutical Preparations; Protein Processing, Post-Translational; Recombinant Proteins; Succinimides; Time Factors | 2019 |
Bacterial l-asparaginases for cancer therapy: Current knowledge and future perspectives.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombination, Genetic | 2019 |
Amino acid metabolism in hematologic malignancies and the era of targeted therapy.
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Asparagine; Cysteine; Glutamine; Hematologic Neoplasms; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Tumor Microenvironment | 2019 |
Mass spectrometric analysis of protein deamidation - A focus on top-down and middle-down mass spectrometry.
Topics: Asparagine; Glutamine; Protein Folding; Proteins; Tandem Mass Spectrometry | 2022 |
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review.
Topics: Asparaginase; Asparagine; Child; Escherichia coli; Glutaminase; Glutamine; Humans; Leukemia | 2022 |
3 trial(s) available for asparagine and glutamine
| Article | Year |
|---|---|
Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase.
Topics: Acinetobacter; Adolescent; Alkalosis, Respiratory; Amidohydrolases; Asparagine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Humans; Hyperglycemia; Leukemia, Lymphoid; Male; Neoplasms | 1979 |
Bacterial glutaminase in treatment of acute leukaemia.
Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Asparagine; Child; Clinical Trials as Topic; Female; Glutaminase; Glutamine; Half-Life; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male | 1976 |
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
940 other study(ies) available for asparagine and glutamine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Amino acid analysis by ion-exchange chromatography using a lithium elution gradient. Influence of methanol concentration and sample pH.
Topics: Amino Acids; Asparagine; Chromatography, Ion Exchange; Glutamates; Glutamine; Granulocytes; Humans; Hydrogen-Ion Concentration; Ion Exchange Resins; Lithium; Methanol | 1975 |
The properties and large-scale production of L-asparaginase from citrobacter.
Topics: Animals; Asparaginase; Asparagine; Citrobacter; Culture Media; Drug Evaluation, Preclinical; Enterobacteriaceae; Fermentation; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Lymphoma, Non-Hodgkin; Mice; Molecular Weight; Neoplasms, Experimental; Oxygen; Stereoisomerism; Temperature; Zea mays | 1975 |
Zoospore chemotaxis in Australian isolates of Phytophthora species.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chemotaxis; Drug Synergism; Ethanol; Fructose; Fungi; Glutamates; Glutamine; Hydrogen-Ion Concentration; Phytophthora; Spores, Fungal; Sucrose | 1976 |
DON, CONV and DONV-II. Inhibition of L-'asparagine synthetase in vivo.
Topics: Amino Acids; Animals; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Azo Compounds; Cells, Cultured; Diazooxonorleucine; DNA; Formates; Glutamine; Levulinic Acids; Ligases; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pancreas | 1976 |
DON, CONV and DONV-III. Pharmacologic and toxicologic studies.
Topics: Amino Acids; Animals; Asparagine; Azo Compounds; Candida; Cells, Cultured; Diazooxonorleucine; Erythrocytes; Escherichia coli; gamma-Glutamyltransferase; Glutamine; In Vitro Techniques; Levulinic Acids; Mice; Mice, Inbred Strains; Protein Binding | 1976 |
Kinetics and properties of L-glutaminase and L-asparaginase activities of Pseudomonas ovalis.
Topics: Asparaginase; Asparagine; Enzyme Induction; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Pseudomonas; Streptomycin; Tetracyclines; Time Factors | 1976 |
Energy-dependent incorporation of sphingolipid precursors and fatty acids in Bacteriodes melaninogenicus.
Topics: Acetates; Asparagine; Bacteroides; Ceramides; Energy Metabolism; Glutamine; Kinetics; NAD; Palmitates; Prevotella melaninogenica; Sphingosine; Vitamin K | 1977 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Maleimide--biochemical, pharmacologic and toxicologic studies. Interaction with L-asparagine metabolism.
Topics: Acid Phosphatase; Amylases; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Drug Interactions; Glutamine; In Vitro Techniques; L-Lactate Dehydrogenase; Maleimides; Mice; Mice, Inbred Strains; Microsomes, Liver; Nucleic Acids; Proteins; Transaminases | 1978 |
Nitrogen assimilation in Rhodopseudomonas acidophila.
Topics: Alanine; Alanine Transaminase; Amino Acid Oxidoreductases; Asparagine; Cell-Free System; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Nitrogen; Rhodopseudomonas | 1978 |
Tumor inhibitory and non-tumor inhibitory L-asparaginases from Pseudomonas geniculata.
Topics: Animals; Antigens, Bacterial; Asparaginase; Asparagine; Cross Reactions; Glutamine; Hydrogen-Ion Concentration; Mice; Molecular Weight; Neoplasms, Experimental; Pseudomonas; Substrate Specificity | 1979 |
[Metabolism of dicarboxylic amino acids and their amides in bacteria of the genus Citrobacter].
Topics: Amides; Amino Acids, Dicarboxylic; Asparagine; Aspartic Acid; Citrobacter; Deamination; Decarboxylation; Enzyme Activation; Glutamates; Glutamine; Hydrogen-Ion Concentration | 1979 |
Inhibition of L-asparagine synthetase by mineral cations.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cations; Dialysis; Glutamine; Leukemia, Experimental; Ligases; Mice; Mice, Inbred Strains; Pancreas; Sulfhydryl Reagents | 1979 |
[Regulation of glutamine synthetase production in streptomycetes].
Topics: Alanine; Amino Acids; Asparagine; Glutamate-Ammonia Ligase; Glutamine; Quaternary Ammonium Compounds; Species Specificity; Streptomyces | 1979 |
[Effect of natural amino acids on ethanol oxidation in isolated rat hepatocytes].
Topics: Amino Acids; Ammonium Chloride; Animals; Asparagine; Ethanol; Female; Glutamine; In Vitro Techniques; Liver; Oxidation-Reduction; Proline; Rats; Structure-Activity Relationship | 1979 |
A note of the amino acid sequence of residues 381--391 of human immunoglobulins gamma chains.
Topics: Amino Acid Sequence; Asparagine; Chemical Phenomena; Chemistry; Chromatography, Gas; Glutamine; Humans; Immunoglobulin gamma-Chains; Immunoglobulin Heavy Chains; Peptides | 1979 |
Folate requirement for blast cell transformation in mixed leukocyte cultures.
Topics: Asparagine; Culture Media; Folic Acid; Glucose; Glutamine; Glutathione; Humans; Lectins; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Thymidine; Time Factors; Tritium; Vitamin B 12 | 1975 |
Re-investigation of the effects of L-glutamine and L-asparagine on the Neurospora crassa NADP-specific glutamate dehydrogenase.
Topics: Asparagine; Chromatography, Ion Exchange; Glutamate Dehydrogenase; Glutamine; Neurospora; Neurospora crassa; Quaternary Ammonium Compounds | 1976 |
Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal.
Topics: Alanine; Asparagine; Azaserine; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Glutamine; Methionine; Mutation; Niacinamide; p-Fluorophenylalanine; Phenylalanine; Stereoisomerism | 1977 |
Glucosamine dependence of Huntington's chorea fibroblasts in culture.
Topics: Asparagine; Fibroblasts; Glucosamine; Glutamine; Glycine; Huntington Disease | 1976 |
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydroxy Acids; Ligases; Liver Neoplasms; Male; Molecular Conformation; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship | 1975 |
Effect of amino acid meals on hepatic alpha-aminoisobutyrate transport and cyclic AMP.
Topics: Adrenalectomy; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Caseins; Cyclic AMP; Diet; Electrolytes; Gelatin; Glutamine; Glycine; Inulin; Liver; Male; Protein Hydrolysates; Rats; Serine; Sodium Glutamate; Stimulation, Chemical | 1975 |
Tyrocidine synthetase system.
Topics: Aminoacylation; Asparagine; Bacillus; Cell Division; Chromatography, DEAE-Cellulose; Glutamine; Leucine; Ligases; Methods; Molecular Weight; Multienzyme Complexes; Ornithine; Phenylalanine; Proline; Time Factors; Tyrocidine; Tyrosine; Tyrothricin; Valine | 1975 |
High affinity uptake of L-Glutamine in rat brain slices.
Topics: 4-Chloromercuribenzenesulfonate; Allyl Compounds; Amino Acids; Aminooxyacetic Acid; Animals; Asparagine; Brain; Carbon Radioisotopes; Dibenzylchlorethamine; Dinitrophenols; Glutamates; Glutamine; Glycine; Kinetics; Male; Ouabain; Proline; Pyrrolidinones; Rats; Sodium; Temperature; Tritium | 1975 |
Glutamine and asparagine as nitrogen donors for reductant-dependent glutamate synthesis in pea roots.
Topics: Ammonia; Asparagine; Glutamates; Glutamine; Kinetics; NAD; Oxidation-Reduction; Plants | 1975 |
Enzyme regulation in neuroblastoma cells in a salts/glucose medium: induction of ornithine decarboxylase by asparagine and glutamine.
Topics: Asparagine; Bucladesine; Carboxy-Lyases; Cell Line; Culture Media; Dactinomycin; Enzyme Induction; Glutamine; Kinetics; Neuroblastoma; Ornithine Decarboxylase; Prostaglandins E; Xanthines | 1977 |
[Polypeptide synthetase activity of chromatin from eukaryotic cells].
Topics: Aminoacylation; Animals; Asparagine; Chromatin; Glutamates; Glutamine; Glycine; Hepatectomy; Liver; Male; NAD; Niacinamide; Peptide Biosynthesis; Poly Adenosine Diphosphate Ribose; Rats; Thymidine | 1978 |
Alternative substrates for glutamate dehydrogenases.
Topics: Adenosine Diphosphate; Ammonia; Animals; Asparagine; Cattle; Glutamate Dehydrogenase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Liver; Neurospora crassa | 1975 |
Letter: Competitive intramolecular displacement of the neutral amide group. Rearrangement and dehydration reactions of asparagine and glutamine.
Topics: Amides; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Hydrogen-Ion Concentration | 1975 |
Potential inhibitors of L-asparagine biosynthesis. 3. Aromatic sulfonyl fluoride analogs of L-asparagine and L-glutamine.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Liver Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sulfones | 1975 |
Enzymes as reagents in peptide synthesis: enzyme-labile protection for carboxyl groups.
Topics: Asparagine; Aspartic Acid; Carboxypeptidases; Chemical Phenomena; Chemistry; Glutamates; Glutamine; Methods; Proteins; Trypsin | 1977 |
Achromobacter L-glutaminase-L-asparaginase: human pharmacology, toxicology, and activity in acute leukemias.
Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Amidohydrolases; Amino Acids; Asparagine; Child; Drug Evaluation; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Vomiting | 1979 |
Amphibian cells in culture. I. Nutritional studies.
Topics: Amino Acids; Animals; Anura; Asparagine; Blood; Cell Division; Cell Line; Culture Media; Glutamates; Glutamine; Purines; Rana pipiens; Xenopus | 1978 |
Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase.
Topics: Amino Acids; Asparaginase; Asparagine; Breast Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA, Neoplasm; Escherichia coli; Female; Glutamine; Glycoproteins; Humans; Melanoma; Neoplasm Proteins; Pancreatic Neoplasms; RNA, Neoplasm; Vibrio | 1978 |
Amino acid chemoreceptors of Bacillus subtilis.
Topics: Amino Acids; Asparagine; Bacillus subtilis; Chemotaxis; Glutamine; Receptors, Drug; Threonine; Valine | 1977 |
Evidence for cycloheximide acting as a glutamine analogue in plant tissue.
Topics: Asparagine; Azaserine; Cycloheximide; Edetic Acid; Glutamine; Plants; Protein Biosynthesis; Puromycin; Zea mays | 1977 |
Nitrogen nutrition and regulation of cephalosporin production in Streptomyces clavuligerus.
Topics: Amino Acids; Asparagine; Cephalosporins; Glutamine; Nitrogen; Quaternary Ammonium Compounds; Spores, Bacterial; Streptomyces; Urea | 1979 |
Effect of mercaptopicolinic acid and of transaminase inhibitors on glycogen synthesis by rat hepatocytes.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Asparagine; Carbohydrates; Cycloserine; Fasting; Glutamine; In Vitro Techniques; Liver; Liver Glycogen; Male; Picolinic Acids; Rats; Sulfhydryl Compounds; Xylitol | 1979 |
Treatment of L5178Y tumor-bearing BDF1 mice with a nonimmunogenic L-glutaminase-L-asparaginase.
Topics: Amidohydrolases; Animals; Antibody Formation; Asparaginase; Asparagine; Drug Therapy, Combination; Glutaminase; Glutamine; Metabolic Clearance Rate; Mice; Neoplasms, Experimental; Polyethylene Glycols | 1979 |
Regulatory interrelations between GABA and polyamines. II. Effect of GABA on ornithine decarboxylase and putrescine levels in cell culture.
Topics: Aminocaproates; Animals; Asparagine; Carboxy-Lyases; Cells, Cultured; gamma-Aminobutyric Acid; Glutamine; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Stimulation, Chemical | 1979 |
Asparaginase production by human clinical isolates of Vibrio succinogenes.
Topics: Asparaginase; Asparagine; Cell-Free System; Glutamine; Humans; Hydrolysis; Species Specificity; Stereoisomerism; Substrate Specificity; Vibrio; Vibrio Infections | 1979 |
A multi-end point in vitro system for detection of new antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparagine; Bacteria; Carbohydrate Metabolism; Cells, Cultured; Culture Media; Drug Evaluation, Preclinical; Glutamine; Leukemia L1210 | 1978 |
Possibilities for a role of L-glutamine and L-asparagine antagonists in the treatment of gastrointestinal cancer.
Topics: Animals; Asparagine; Azo Compounds; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Glutamine; Humans; Leukemia L1210; Mice; Tryptophan | 1979 |
Isotachophoretic analysis of serum for aspartic acid, asparagine, glutamic acid and glutamine.
Topics: Asparagine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Glutamates; Glutamine; Humans | 1978 |
[Recovery after complete cerebral ischemia: free amino acid levels in the brain tissue during and after complete cerebral ischemia (author's transl)].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cats; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ischemic Attack, Transient | 1978 |
Consequences of aspartase deficiency in Yersinia pestis.
Topics: Amino Acids; Ammonia-Lyases; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Glutamates; Glutamine; Proline; Yersinia; Yersinia pestis | 1978 |
Enhancement of melphalan therapy with glutaminase:asparaginase.
Topics: Acinetobacter; Animals; Asparaginase; Asparagine; Drug Synergism; Glutaminase; Glutamine; Leukemia L1210; Melphalan; Mice; Time Factors | 1978 |
Inhibition of sickling in erythrocytes by amino acids.
Topics: Amino Acids; Anemia, Sickle Cell; Asparagine; Erythrocytes; Glutamine; Hemoglobin, Sickle; Homoserine; Humans | 1975 |
Regulation of nitrogenase synthesis in intact cells of Rhodospirillum rubrum: inactivation of nitrogen fixation by ammonia, L-glutamine and L-asparagine.
Topics: Acetylene; Amino Acids; Ammonia; Anaerobiosis; Asparaginase; Asparagine; Cell-Free System; Enzyme Repression; Glutamine; Nitrogen Fixation; Nitrogenase; Oxidation-Reduction; Rhodospirillum rubrum; Stereoisomerism | 1975 |
Sources of ammonia for urea synthesis in isolated rat liver cells.
Topics: Alanine; Aminooxyacetic Acid; Ammonium Chloride; Animals; Asparagine; Glucose; Glutamine; Glycine; Lactates; Leucine; Liver; Ornithine; Rats; Urea; Valine | 1977 |
Stimulatory effect of intraportal ammonia on plasma uric acid concentration and urinary uric acid excretion in chickens fed a low protein diet.
Topics: Ammonia; Animals; Asparagine; Chickens; Glutamine; Inosine; Liver; Male; Protein Deficiency; Quaternary Ammonium Compounds; Uric Acid | 1977 |
Applications of gas-liquid chromatography in protein chemistry. II. Determination of amide residues in nanomolar amounts of proteins.
Topics: Amides; Ammonia; Asparagine; Chromatography, Gas; Chromatography, Liquid; Glutamine; Hydrolysis; Methods; Microchemistry; Proteins | 1977 |
Some features of secretory systems in plants.
Topics: Ammonia; Asparagine; Calcium; Cell Wall; Colchicine; Cytochalasin B; Cytoplasm; Glutamine; Golgi Apparatus; Phenylalanine; Plant Cells; Plant Proteins; Plants; Urea; Uric Acid | 1977 |
Enhancement of glycogen synthesis in isolated perfused rat liver [proceedings].
Topics: Animals; Asparagine; Fasting; Glutamine; In Vitro Techniques; Liver; Liver Glycogen; Perfusion; Rats | 1977 |
Carboxypeptidase C.
Topics: Acetylesterase; Amino Acid Sequence; Aminopeptidases; Asparagine; Carboxypeptidases; Endopeptidases; Glutamine; Plants; Proteins; Substrate Specificity | 1977 |
Differentiation of Claviceps purpurea in axenic culture.
Topics: Amino Acids; Asparagine; Aspartic Acid; Claviceps; Ergot Alkaloids; Glutamates; Glutamine; Lipids; Morphogenesis; Spores, Fungal; Triglycerides | 1976 |
Solution conformation of a retro-D analogue of tocinamide.
Topics: Asparagine; Circular Dichroism; Dimethyl Sulfoxide; Disulfides; Glutamine; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxytocin; Solutions; Water | 1976 |
The binding of asparagine, glutamine and homoserine to human erythrocytes containing hemoglobins S and CS and to soluble hemoglobins S and CS.
Topics: Asparagine; Binding Sites; Computers; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutamine; Hemoglobin, Sickle; Hemoglobins; Homoserine; Humans; Kinetics; Oxyhemoglobins; Protein Binding | 1976 |
[Dicarboxylic amino acids anf total glutathione in chronic nonspecific pneumonias in children].
Topics: Adolescent; Asparagine; Child; Child, Preschool; Chronic Disease; Glutamine; Glutathione; Humans; Infant; Pneumonia | 1976 |
Utilization of amino acids by the isolated perfused sheep liver.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blood Flow Velocity; Glutamine; Glycine; In Vitro Techniques; Liver; Nitrogen; Organ Size; Oxygen Consumption; Protein Biosynthesis; Regional Blood Flow; Sheep; Urea | 1975 |
Instability and function: ascorbic acid and glutaminyl and asparaginyl residues.
Topics: Ascorbic Acid; Asparagine; Binding Sites; Chemical Phenomena; Chemistry; Glutamine; Peptides; Protein Binding; Proteins; Transferrin | 1975 |
Amino acid metabolism of platelets in leukemia.
Topics: Amino Acids; Asparagine; Aspartic Acid; Blood Platelets; Glucose; Glutamates; Glutamine; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous | 1976 |
Radiation-induced murine leukemia ERLD in cell culture.
Topics: Animals; Antigens, Neoplasm; Asparagine; Cell Line; Chromosome Aberrations; Culture Media; Glutamine; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Radiation-Induced; Mercaptoethanol; Mice; Mice, Inbred C57BL | 1976 |
Stimulation of hepatic glycogen synthesis by amino acids.
Topics: Alanine; Amino Acids; Ammonium Chloride; Animals; Asparagine; Cells, Cultured; Dihydroxyacetone; Fructose; Glucose; Glutamine; Glycogen; Kinetics; Lactates; Liver; Male; Rats | 1976 |
A method of distinguishing between aspartic acid and asparagine and between glutamic acid and glutamine during sequence analysis by the dansyl-Edman procedure.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Bees; Chymotrypsin; Dansyl Compounds; Glutamates; Glutamine; Methods; Pepsin A; Thermolysin; Trypsin; Venoms | 1975 |
Effect of Acinetobacter glutaminase-asparaginase treatment on free amino acids in mouse tissues.
Topics: Acetyltransferases; Acinetobacter; Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Body Weight; Brain; Escherichia coli; Female; Glutamates; Glutaminase; Glutamine; Kidney; Mice; Organ Size; Serine; Spleen; Threonine | 1975 |
Effects on specific antibodies on the catalytic activity of L-asparaginase from Serratia marcescens and Escherichia coli.
Topics: Animals; Antibodies, Bacterial; Antibody Specificity; Asparaginase; Asparagine; Catalysis; Cross Reactions; Escherichia coli; Glutamine; Hydrolysis; Kinetics; Rabbits; Serratia marcescens; Stereoisomerism | 1975 |
Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen source.
Topics: Asparagine; Benzenesulfonates; Candida albicans; Cryptococcus; Cryptococcus neoformans; Dihydroxyphenylalanine; Glutamine; Glycine; Hydroxybenzoates; Molecular Weight; Nitrogen; Phenols; Pigments, Biological; Solubility; Species Specificity | 1975 |
Asparagine metabolism in the bovine lens: a comparison with the metabolism of aspartic acid.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Biological Transport; Cattle; Eye Proteins; Glutamates; Glutamine; Glutathione; Lactates; Lens, Crystalline; Proline | 1975 |
An asparagine requirement in young rats fed the dietary combinations of aspartic acid, glutamine, and glutamic acid.
Topics: Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartic Acid; Body Weight; Deficiency Diseases; DNA; Drug Synergism; Glutamates; Glutamine; Liver; Male; Muscles; Myocardium; Nutritional Requirements; Organ Size; Protein Biosynthesis; Rats | 1975 |
Structural alterations of amino acids at the level of aminoacyl-tRNAs: transformation of dicarboxylic amino acids.
Topics: Amino Acids, Dicarboxylic; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartate-tRNA Ligase; Brain; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Paper; Electrophoresis, Paper; Glutamate-tRNA Ligase; Glutamine; Male; RNA, Transfer; Transfer RNA Aminoacylation | 1975 |
Structural alterations of amino acids at the level of aminoacyl-tRNAs: identification of the transformation products of dicarboxylic amino acids.
Topics: Amino Acids, Dicarboxylic; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartate-tRNA Ligase; Brain; Cattle; Chromatography, Paper; Electrophoresis, Paper; Glutamate-tRNA Ligase; Glutamine; History, Medieval; Hydrolysis; RNA, Transfer; Transfer RNA Aminoacylation | 1975 |
The terminal amino acids of protein sequences and protein maturation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Cell Nucleus; Codon; Glutamine; Lysine; Methionine; Peptide Chain Termination, Translational; Peptide Hydrolases; Phenylalanine; Protein Biosynthesis; Serine | 1975 |
Thin-layer chromatography on a chromatosheet coated with resin in different ionic forms for the separation of amino acid mixtures containing asparagine and glutamine.
Topics: Asparagine; Buffers; Chromatography, Ion Exchange; Chromatography, Thin Layer; Citrates; Glutamine; Ion Exchange Resins; Lithium; Mathematics | 1975 |
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
[Regulation of nitrogenase from lupin bacteroids].
Topics: Acetylene; Alanine; Amides; Amino Acids; Asparagine; Aspartic Acid; Glutamates; Glutamine; Glyoxylates; Hydroxybutyrates; Keto Acids; Ketoglutaric Acids; Nitrogenase; Oxaloacetates; Rhizobium | 1975 |
Carbohydrate and amino acid metabolism in rat cerebral cortex in moderate and extreme hypercapnia.
Topics: Acute Disease; Alanine; Amino Acids; Ammonia; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Cerebral Cortex; Citric Acid Cycle; Fructosephosphates; gamma-Aminobutyric Acid; Glucosephosphates; Glutamates; Glutamine; Glycogen; Glycolysis; Hypercapnia; Lactates; Male; Pyruvates; Rats | 1975 |
Intestinal metabolism of glutamine and glutamate from the lumen as compared to glutamine from blood.
Topics: Amino Acids; Animals; Arteries; Asparagine; Blood Flow Velocity; Glutamates; Glutamine; Jejunum; Kinetics; Male; Rats | 1975 |
Detection of asparagine and glutamine in peptides sequenced by dipeptidyl aminopeptidase I via gas chromatography-mass spectrometry.
Topics: Aminopeptidases; Asparagine; Chromatography, Thin Layer; Dipeptidases; Gas Chromatography-Mass Spectrometry; Glutamine; Peptides | 1976 |
Identification of asparagine, glutamine and the carboxyl-terminal amino acids in polypeptides via sequence analysis by gas chromatography-mass spectrometry.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Peptides | 1976 |
Letter: Improved cation-exchange separation of asparagine and glutamine in the presence of other amino acids.
Topics: Amino Acids; Asparagine; Cation Exchange Resins; Chromatography, Ion Exchange; Glutamine; Humans | 1976 |
The inhibition of lymphocyte blastogenesis by asparaginase: critical role of glutamine in both T and B lymphocyte transformation.
Topics: Asparaginase; Asparagine; B-Lymphocytes; Cell Division; Cells, Cultured; Glutamine; Humans; Lymphocyte Activation; T-Lymphocytes | 1992 |
Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium beta-glucosidase.
Topics: Asparagine; Aspartic Acid; beta-Glucosidase; Binding Sites; Deuterium; Drug Stability; Glucosides; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rhizobium; Structure-Activity Relationship | 1992 |
Specificity of the permissive effect of D-glucose on insulin release in chicken pancreas.
Topics: 3-O-Methylglucose; Animals; Asparagine; Chickens; Glucose; Glutamine; Glyceraldehyde; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Mannose; Methylglucosides; Perfusion | 1992 |
Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products.
Topics: Ammonia; Animals; Asparagine; Cell Division; Cell Line; Cells, Cultured; Cricetinae; Female; Glucose; Glutamine; Kinetics; Lactates; Lactic Acid; Ovary; Oxidation-Reduction | 1990 |
Chinese hamster ovary cell growth and interferon production kinetics in stirred batch culture.
Topics: Ammonia; Animals; Asparagine; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; Female; Glucose; Glutamine; Interferon-gamma; Kinetics; Lactates; Lactic Acid; Ovary | 1991 |
Role of Asp-9 and Glu-36 in the active site of the pneumococcal CPL1 lysozyme: an evolutionary perspective of lysozyme mechanism.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Binding Sites; Biological Evolution; DNA Mutational Analysis; Glutamine; Molecular Sequence Data; Muramidase; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology; Streptococcus pneumoniae; Structure-Activity Relationship | 1992 |
Role of glycosylation on the secretion and biological activity of erythropoietin.
Topics: Animals; Asparagine; Carbohydrate Conformation; Carbohydrates; Cell Line; CHO Cells; Cricetinae; Erythropoietin; Glutamine; Glycosylation; Immunoblotting; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Transfection | 1992 |
Effects of baclofen on amino acid release.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Asparagine; Baclofen; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamine; Glycine; Potassium; Rats; Taurine | 1992 |
Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn.
Topics: Amino Acid Sequence; Anions; Asparagine; Aspartic Acid; Bacteriorhodopsins; Binding Sites; Glutamine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Recombinant Proteins; Schiff Bases; Sodium Chloride; Spectrophotometry | 1992 |
A bifunctional xylanase encoded by the xynA gene of the rumen cellulolytic bacterium Ruminococcus flavefaciens 17 comprises two dissimilar domains linked by an asparagine/glutamine-rich sequence.
Topics: Amino Acid Sequence; Animals; Asparagine; Bacteria, Anaerobic; Bacterial Proteins; Base Sequence; Cattle; Cellulose; Cloning, Molecular; Codon; DNA, Bacterial; Escherichia coli; Glutamine; Glycoside Hydrolases; Gram-Positive Cocci; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Xylan Endo-1,3-beta-Xylosidase | 1992 |
Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant.
Topics: Amino Acid Sequence; Animals; Asparagine; Crystallography; Disulfides; Glutamine; Hydrogen Bonding; Immunoglobulin Fab Fragments; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; In Vitro Techniques; Mice; Models, Molecular; Molecular Sequence Data; Protein Conformation; Recombinant Fusion Proteins; X-Ray Diffraction | 1992 |
A missense (Asp250----Asn) mutation in the lipoprotein lipase gene in two unrelated families with familial lipoprotein lipase deficiency.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Exons; Female; Gene Expression; Glutamine; Humans; Lipase; Lipoprotein Lipase; Male; Molecular Sequence Data; Mutation; Pedigree; Polymerase Chain Reaction | 1992 |
Sequence and structure determinants of the nonenzymatic deamidation of asparagine and glutamine residues in proteins.
Topics: Amino Acid Sequence; Asparagine; Computer Simulation; Cytochrome c Group; Glutamine; Hemoglobin J; Hemoglobins, Abnormal; Humans; Insulin; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease, Pancreatic; Triose-Phosphate Isomerase | 1991 |
Oxytocin antagonists with changes in the Asn5 position shed light on hormone-oxytocin receptor interactions.
Topics: Amino Acid Sequence; Animals; Asparagine; Drug Combinations; Female; Glutamine; Molecular Sequence Data; Oxytocin; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Oxytocin; Serine; Structure-Activity Relationship; Uterine Contraction | 1991 |
Changes in binding activity of luteinizing hormone receptors by site directed mutagenesis of potential glycosylation sites.
Topics: Animals; Asparagine; Binding Sites; Carbohydrate Conformation; Cell Line; Female; Genetic Vectors; Glutamine; Glycosylation; Humans; Mutagenesis, Site-Directed; Ovary; Protein Conformation; Rats; Receptors, LH; Transfection | 1991 |
Adaptive regulation of brush-border amino acid transport in a chronic excluded jejunal limb.
Topics: Alanine; Anastomosis, Roux-en-Y; Asparagine; Biological Transport, Active; Glucose; Glutaminase; Glutamine; Histidine; Jejunum; Kinetics; Microvilli; Sodium | 1991 |
Effects of Asp-96----Asn, Asp-85----Asn, and Arg-82----Gln single-site substitutions on the photocycle of bacteriorhodopsin.
Topics: Arginine; Asparagine; Aspartic Acid; Bacteriorhodopsins; Biological Transport, Active; Glutamine; Halobacterium; In Vitro Techniques; Kinetics; Light; Photosynthesis; Recombinant Proteins; Retinaldehyde; Schiff Bases; Spectrum Analysis; Structure-Activity Relationship | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Distribution of glutamine and asparagine residues and their near neighbors in peptides and proteins.
Topics: Amino Acid Sequence; Asparagine; Databases, Factual; Glutamine; Molecular Sequence Data; Peptides; Proteins; Software | 1991 |
Molecular mechanisms of the irreversible thermal denaturation of guinea-pig liver transglutaminase.
Topics: Animals; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutamine; Guinea Pigs; Hot Temperature; Liver; Oxidation-Reduction; Protein Denaturation; Transglutaminases | 1990 |
Purification and functional characterization of the Glu-tRNA(Gln) amidotransferase from Chlamydomonas reinhardtii.
Topics: Adenosine Triphosphate; Ammonia; Asparagine; Azo Compounds; Binding Sites; Chlamydomonas; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamates; Glutamic Acid; Glutamine; Magnesium; Molecular Weight; Nitrogenous Group Transferases; Norleucine; Phosphorylation; Protein Denaturation; RNA, Transfer, Amino Acyl; Spectrophotometry; Substrate Specificity; Transferases | 1990 |
Determinants of visual pigment absorbance: identification of the retinylidene Schiff's base counterion in bovine rhodopsin.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Glutamates; Glutamic Acid; Glutamine; Kinetics; Membranes; Models, Molecular; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Schiff Bases; Spectrophotometry | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Functional reconstitution of the hepatic system N amino acid transport activity.
Topics: Animals; Asparagine; Biological Transport, Active; Cell Membrane; Detergents; Glutamine; Histidine; Kinetics; Liposomes; Liver; Membrane Proteins; Polyethylene Glycols; Proteolipids; Rats; Substrate Specificity | 1991 |
Site-directed mutagenesis of the human thyrotropin receptor: role of asparagine-linked oligosaccharides in the expression of a functional receptor.
Topics: Animals; Asparagine; Cell Line; Codon; Cricetinae; DNA; Gene Expression; Glutamine; Glycosylation; Humans; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Oligosaccharides; Receptors, Thyrotropin; Signal Transduction; Thyrotropin; Transfection | 1991 |
Transport of asparagine by rat brain synaptosomes: an approach to evaluate glutamine accumulation.
Topics: Amino Acids; Animals; Asparagine; Biological Transport; Brain; Glutamine; Kinetics; Male; Rats; Rats, Inbred Strains; Synaptosomes; Time Factors | 1991 |
Structure-function studies of Na,K-ATPase. Site-directed mutagenesis of the border residues from the H1-H2 extracellular domain of the alpha subunit.
Topics: Animals; Asparagine; Cell Membrane; DNA; Glutamine; Macromolecular Substances; Models, Structural; Mutation; Ouabain; Protein Conformation; Sheep; Sodium-Potassium-Exchanging ATPase | 1990 |
Carbohydrate structures of a human tissue plasminogen activator variant expressed in recombinant Chinese hamster ovary cells.
Topics: Animals; Asparagine; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Clone Cells; Cricetinae; Cricetulus; Genetic Variation; Glutamine; Glycoproteins; Glycosylation; Humans; Methylation; Molecular Sequence Data; Oligosaccharides; Plasminogen Activators; Recombinant Proteins | 1990 |
Swelling of rat hepatocytes stimulates glycogen synthesis.
Topics: Alanine; Aminoisobutyric Acids; Animals; Asparagine; Glutamine; In Vitro Techniques; Liver; Liver Glycogen; Organ Size; Osmolar Concentration; Proline; Raffinose; Rats; Sucrose | 1990 |
Conserved residues make similar contacts in two repressor-operator complexes.
Topics: Amino Acid Sequence; Asparagine; Base Composition; Base Sequence; Binding Sites; DNA-Binding Proteins; Glutamine; Hydrogen Bonding; Molecular Sequence Data; Molecular Structure; Operator Regions, Genetic; Protein Conformation; Repressor Proteins; Transcription Factors; Viral Proteins; Viral Regulatory and Accessory Proteins | 1990 |
Facile SPS of peptides having C-terminal Asn and Gln.
Topics: Amino Acids; Asparagine; Fluorenes; Glutamine; Methylene Chloride; Peptides; Trifluoroacetic Acid | 1990 |
Solid-phase synthesis of peptides with C-terminal asparagine or glutamine. An effective, mild procedure based on N alpha-fluorenylmethyloxycarbonyl (Fmoc) protection and side-chain anchoring to a tris(alkoxy)benzylamide (PAL) handle.
Topics: Amino Acids; Asparagine; Dimethylformamide; Fluorenes; Glutamine; Humans; Oligopeptides; Proinsulin; Thymic Factor, Circulating; Trifluoroacetic Acid; Valerates | 1990 |
Detection of methylated asparagine and glutamine residues in polypeptides.
Topics: Amino Acid Sequence; Asparagine; Bacteria; Chromatography, High Pressure Liquid; Glutamine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Molecular Sequence Data; Phenylthiohydantoin | 1990 |
The proton pore of the F0F1-ATPase of Escherichia coli: Ser-206 is not required for proton translocation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Base Sequence; Dicyclohexylcarbodiimide; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Fluorescence; Glutamine; Ion Channels; Oxidative Phosphorylation; Proton-Translocating ATPases; Protons; Quinacrine; Serine | 1988 |
Transport characteristics of glutamine in human intestinal brush-border membrane vesicles.
Topics: Asparagine; Biological Transport; Electrochemistry; Glutamine; Humans; Intestinal Absorption; Kinetics; Male; Membrane Potentials; Microvilli; Middle Aged; Osmolar Concentration; Potassium; Serine; Sodium; Temperature; Valinomycin | 1989 |
Transport of glutamine in rat intestinal brush-border membrane vesicles.
Topics: Animals; Asparagine; Biological Transport; Electrochemistry; Glutamine; Intestinal Mucosa; Kinetics; Male; Membrane Potentials; Microvilli; Osmolar Concentration; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Serine; Sodium; Thiocyanates; Valinomycin | 1989 |
Glutamine- vs glucose-supported motor activity in Schistosoma mansoni: physiological relevance of aerobic metabolism.
Topics: Adenine Nucleotides; Aerobiosis; Alanine; Animals; Asparagine; Carbon Dioxide; Energy Metabolism; Glucose; Glutamates; Glutamine; Movement; Oxygen Consumption; Schistosoma mansoni | 1989 |
Nucleotide sequences of Dictyostelium discoideum developmentally regulated cDNAs rich in (AAC) imply proteins that contain clusters of asparagine, glutamine, or threonine.
Topics: Asparagine; Base Sequence; Blotting, Northern; Blotting, Southern; Codon; Dictyostelium; DNA Probes; DNA, Circular; Genes; Glutamine; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Threonine | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Functional consequences of glutamate, aspartate, glutamine, and asparagine mutations in the stalk sector of the Ca2+-ATPase of sarcoplasmic reticulum.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Cloning, Molecular; Glutamates; Glutamic Acid; Glutamine; Immunoblotting; Microsomes; Molecular Sequence Data; Muscles; Mutation; Phosphorylation; Rabbits; Recombinant Fusion Proteins; Sarcoplasmic Reticulum; Transfection | 1989 |
Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation.
Topics: Animals; Asparaginase; Asparagine; Biological Transport; Cell Survival; DNA Replication; Glutamates; Glutamic Acid; Glutamine; Kinetics; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Peptides; Polyglutamic Acid | 1985 |
The effect of asparagine and adenine on the glutamine requirement for growth of human peripheral lymphocytes.
Topics: Adenine; Asparagine; Cell Division; Cells, Cultured; Glutamine; Humans; Kinetics; Lymphocytes | 1989 |
Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Histidine; Mathematics; Models, Molecular; Phenylalanine; Ribonuclease, Pancreatic; Sulfates; Tyrosine; X-Ray Diffraction | 1989 |
Features of myocardial metabolism of some amino acids and ammonia in patients with coronary artery disease.
Topics: Adult; Alanine; Amino Acids; Ammonia; Asparagine; Cardiac Pacing, Artificial; Coronary Disease; Evaluation Studies as Topic; Glucose; Glutamates; Glutamine; Humans; Lactates; Male; Middle Aged; Myocardium | 1989 |
Nephritogenic glycoprotein. XII. Focal glomerulonephritis with myeloid bodies produced in rats by synthetic analogues of the glycopeptide, nephritogenoside.
Topics: Animals; Asparagine; Cells, Cultured; Disease Models, Animal; Fluorescent Antibody Technique; Glomerulonephritis; Glutamine; Glycopeptides; Humans; Inclusion Bodies; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred Strains; Trisaccharides | 1987 |
Separation of amino acid and amide nitrogen from plant extracts for 15N analysis.
Topics: Amides; Amino Acids; Ammonia; Asparagine; Aspartic Acid; Chromatography, Ion Exchange; Fabaceae; Glutamates; Glutamic Acid; Glutamine; Nitrogen; Nitrogen Isotopes; Plants; Plants, Medicinal | 1986 |
Post-translational modifications of chloroperoxidase from Caldariomyces fumago.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Chloride Peroxidase; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Isoenzymes; Mitosporic Fungi; Peptide Fragments; Peroxidases; Protein Conformation; Protein Processing, Post-Translational; Protein Sorting Signals | 1987 |
Covalent attachment of oligosaccharide-asparagine derivatives: incorporation into glutamine residues with the enzyme transglutaminase.
Topics: Animals; Asparagine; Caseins; Glutamine; Glycoproteins; Guinea Pigs; Indicators and Reagents; Liver; Oligosaccharides; Ribonuclease, Pancreatic; Transglutaminases | 1987 |
Characterization of the glutamyl-tRNA(Gln)-to-glutaminyl-tRNA(Gln) amidotransferase reaction of Bacillus subtilis.
Topics: Ammonia; Asparagine; Bacillus subtilis; Diazooxonorleucine; Glutamate-Ammonia Ligase; Glutamine; Hot Temperature; Methionine Sulfoximine; Mutation; Nitrogenous Group Transferases; RNA, Transfer, Amino Acyl; RNA, Transfer, Gln; Transferases | 1988 |
Topographical distribution of neurochemical changes in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids, Dicarboxylic; Asparagine; Aspartic Acid; Cerebellar Cortex; Cerebral Cortex; Choline O-Acetyltransferase; Glutamates; Glutaminase; Glutamine; Humans; Middle Aged; Somatostatin | 1988 |
Influence of total nitrogen, asparagine, and glutamine on MCA tumor growth in the Fischer 344 rat.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamic Acid; Glutamine; Male; Nitrogen; Organ Size; Parenteral Nutrition, Total; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1988 |
Glutamine and asparagine synthesis in the nematodes Heligmosomoides polygyrus and Panagrellus redivivus.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Glutamate-Ammonia Ligase; Glutamine; Heligmosomatoidea; Nematoda; Nematospiroides dubius | 1988 |
Mn2+-probe ESR method for the analyses of the dissociation of charged residues on the surface of immunoglobulins.
Topics: Asparagine; Binding Sites, Antibody; Crystallography; Electron Spin Resonance Spectroscopy; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Immunoglobulin A; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Manganese; Myeloma Proteins | 1986 |
Amino-aromatic interactions in proteins.
Topics: Arginine; Asparagine; Crystallography; Glutamine; Histidine; Lysine; Proteins | 1986 |
Why is one Bacillus alpha-amylase more resistant against irreversible thermoinactivation than another?
Topics: alpha-Amylases; Amides; Asparagine; Bacillus; Electrochemistry; Geobacillus stearothermophilus; Glutamine; Half-Life; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Lysine; Protein Conformation; Starch; Thermodynamics | 1988 |
Mechanisms of irreversible thermal inactivation of Bacillus alpha-amylases.
Topics: Acetamides; alpha-Amylases; Amides; Asparagine; Bacillus; Chemical Precipitation; Chromatography, High Pressure Liquid; Cysteine; Enzyme Activation; Geobacillus stearothermophilus; Glutamine; Half-Life; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Oxidation-Reduction; Protein Conformation; Sulfhydryl Compounds; Thermodynamics | 1988 |
Tertiary structure is a principal determinant to protein deamidation.
Topics: Amides; Asparagine; Computer Graphics; Glutamine; Hydrogen Bonding; Models, Molecular; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Trypsin | 1988 |
Site-specific glycosylation in animal cells. Substitution of glutamine for asparagine 293 in chicken ovalbumin does not allow glycosylation of asparagine 312.
Topics: Amidohydrolases; Animals; Asparagine; Base Sequence; Chickens; DNA, Recombinant; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycosylation; L Cells; Mice; Mutation; Nucleic Acid Hybridization; Oligosaccharides; Ovalbumin; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Plasmids; Transfection; Transformation, Genetic | 1988 |
Capillary gas chromatography of amino acids, including asparagine and glutamine: sensitive gas chromatographic-mass spectrometric and selected ion monitoring gas chromatographic-mass spectrometric detection of the N,O(S)-tert.-butyldimethylsilyl derivativ
Topics: Amino Acids; Animals; Asparagine; Cattle; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Glutamine; Hydrolysis; Organosilicon Compounds; Peptides; Silicon | 1987 |
Interaction of metabolism of aspartate and inosine and energy state of malignant cells.
Topics: Adenosine Triphosphate; Animals; Asparagine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Cells, Cultured; Energy Metabolism; Glutamine; Inosine; Lactates; Lactic Acid; Mice; Oxygen Consumption; Proline | 1987 |
Sensitive analysis of asparagine and glutamine in physiological fluids and cells by precolumn derivatization with phenylisothiocyanate and reversed-phase high-performance liquid chromatography.
Topics: Amino Acids; Animals; Asparagine; Body Fluids; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocytes; Glutamine; Humans; Isothiocyanates; Leukemia L5178; Spectrophotometry, Ultraviolet; Thiocyanates | 1986 |
In vitro deamidation of human triosephosphate isomerase.
Topics: Asparagine; Buffers; Carbohydrate Epimerases; Dihydroxyacetone Phosphate; Glutamine; Glyceraldehyde 3-Phosphate; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Isoenzymes; Osmolar Concentration; Temperature; Triose-Phosphate Isomerase | 1986 |
Chemical mutations of the catalytic carboxyl groups in lysozyme to the corresponding amides.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chromatography, Affinity; Glutamates; Glutamine; Kinetics; Muramidase; Mutation; Sulfonamides | 1986 |
Effect of the add-back process on the free amino acid pool of potatoes.
Topics: Amines; Amino Acids; Asparagine; Chromatography, Gas; Food Handling; Glutamine; Vegetables | 1986 |
Therapeutic efficacy of asparaginase encapsulated in intact erythrocytes.
Topics: Animals; Asparaginase; Asparagine; Erythrocytes; Female; Glutamine; Lymphoma; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
Model for interactions of amino acid side chains with Watson-Crick base pair of guanine and cytosine: crystal structure of 9-(2-carbamoylethyl)guanine and 1-methylcytosine complex.
Topics: Asparagine; Crystallography; Cytosine; DNA; DNA-Binding Proteins; Glutamine; Guanine; Hydrogen Bonding; Models, Molecular; Models, Structural; Nucleic Acid Conformation | 1985 |
Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Asparagine; Binding Sites; Genes; Geobacillus stearothermophilus; Glutamine; Histidine; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Tyrosine-tRNA Ligase | 1985 |
[Enzyme induction and metabolic regulation in mycobacteria. 3. Induction of enzymatic hydrolysis and utilization of amides in M. smegmatis].
Topics: Acetates; Amides; Amidohydrolases; Arylformamidase; Asparagine; Butyrates; Caproates; Chloramphenicol; Enzyme Induction; Formamides; Glutamine; Mycobacterium; Oxygen Consumption; Propionates; Succinates; Urea; Valerates | 1970 |
The activation of Mg++-dependent ATPase by aspartic and glutamic acids.
Topics: Adenosine Triphosphatases; Alanine; Asparagine; Aspartic Acid; Cell Membrane; Cell Membrane Permeability; Depression, Chemical; Enzyme Activation; Erythrocytes; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine; Magnesium; Potassium; Saponins; Serine; Sodium | 1970 |
[Effect of administration of amino acids, especially of L-DOPA and -methyldopa, on the composition of cerebrospinal fluid in extrapyramidal syndromes. 3. Alterations of cerebrospinal fluid in patients with Huntington's chorea after -methyldopa or L-DOPA
Topics: Adult; Aged; Alanine Transaminase; Asparagine; Aspartic Acid; Child; Dihydroxyphenylalanine; Female; Glutamates; Glutamine; Glycine; Humans; Huntington Disease; Male; Methyldopa; Middle Aged; Phenylalanine; Pyruvates; Threonine | 1973 |
[Proceedings: Catabolic repression by nitrogen of arginase synthesis in Saccharomyces cerevisiae].
Topics: Ammonia; Arginase; Asparagine; Enzyme Repression; Genes; Glutamine; Nitrogen; Saccharomyces cerevisiae | 1974 |
[Effect of specific amino acids on the hot-bath-test in multiple sclerosis patients].
Topics: Amino Acids; Asparagine; Body Temperature; Epinephrine; Female; Flicker Fusion; Glutamine; Humans; Male; Multiple Sclerosis; Neurotransmitter Agents; Norepinephrine; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine | 1973 |
Immunosuppressive enzymes.
Topics: Animals; Antigens; Asparaginase; Asparagine; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Glutamine; Graft vs Host Reaction; Hemocyanins; Hemolytic Plaque Technique; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Neoplasms; Sheep; Skin Tests; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous | 1973 |
Ammonium repression in a mutant of Saccharomyces carlsbergensis lacking NADP dependent glutamate dehydrogenase activity.
Topics: Allantoin; Amidohydrolases; Ammonium Sulfate; Asparagine; Diploidy; Genes, Regulator; Genotype; Glutamate Dehydrogenase; Glutamine; Mutation; NADP; Saccharomyces | 1973 |
Evidence for the presence of glutamate synthase in extracts of carrot cell cultures.
Topics: Ammonium Chloride; Asparagine; Cells, Cultured; Chromatography, Gel; Dialysis; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Kinetics; NAD; NADP; Nitrates; Oxidation-Reduction; Plants; Spectrophotometry, Ultraviolet; Transaminases | 1974 |
Glutamate synthetase type activity in higher plants.
Topics: Asparagine; Cells, Cultured; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Plants; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; Transaminases | 1974 |
Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex.
Topics: Acetone; Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Citrates; Citric Acid Cycle; Fructosephosphates; Fumarates; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycerophosphates; Ischemia; Ketoglutaric Acids; Malates; Male; Methods; Phosphates; Rats; Succinates | 1974 |
Chromatographic analysis of the bleeding sap of inoculated and non-inoculated soya plants.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Paper; Glutamine; Glycine max; Injections; Leucine; Nitrogen; Rhizobium; Serine; Valine | 1967 |
Enzymes as immunosuppressants: basic considerations.
Topics: Alanine; Asparaginase; Asparagine; Carbon Isotopes; Concanavalin A; Diazonium Compounds; Electrophoresis, Polyacrylamide Gel; Enzymes; Erwinia; Fusarium; Glutamine; Humans; Immunosuppressive Agents; Lymphocytes; Mycobacterium tuberculosis; Proteins; Valine | 1973 |
Suppression of skin hypersensitivity and antibody formation by L-asparaginase.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Arthus Reaction; Asparaginase; Asparagine; Escherichia coli; Female; Freund's Adjuvant; Glutamine; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocytes; Male; Precipitin Tests; Rabbits; Serum Albumin, Bovine; Skin Tests | 1970 |
[Nutritive sources in mycobacteria. 3. The influence of serum on the metabolism of M. smegmatis].
Topics: Acetates; Amides; Amidohydrolases; Amino Acids; Asparagine; Chromatography, Paper; Colorimetry; Culture Media; Formamides; Glutamine; Glycerol; Isonicotinic Acids; Mycobacterium; Niacinamide; Oxygen Consumption; Propionates; Pyrazinamide; Succinates; Urea | 1968 |
Formation of asparagine from aspartic acid in rat brain.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Ammonium Chloride; Animals; Animals, Newborn; Asparaginase; Asparagine; Aspartic Acid; Brain; Carbon Isotopes; Centrifugation; Chromatography; Electrophoresis; Glucose; Glutamine; Hydrogen-Ion Concentration; Male; Mitochondria; Rats | 1970 |
The structure of the cell wall peptidoglycan of Bifidobacterium bifidum var. pennsylvanicus.
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Cell Wall; Chromatography, Gel; Chromatography, Paper; Cycloserine; Dinitrophenols; Electrophoresis; Fluorine; Glucosamine; Glutamine; Glycosaminoglycans; Hydrazines; Hydrolysis; Lactobacillus; Models, Structural; Muramidase; Nucleoside Diphosphate Sugars; Ornithine; Paper; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Stereoisomerism; Uracil Nucleotides | 1971 |
The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Culture Techniques; Glucose; Glutamates; Glutamine; Liver Neoplasms; Rats; Sarcoma, Experimental | 1966 |
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; Diphosphates; Female; Glutamine; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Liver Neoplasms; Magnesium; Manganese; Neoplasms, Experimental; Potassium; Rats | 1968 |
Sources of nitrogen as rate-limiting factors for purine biosynthesis de novo in Ehrlich ascites tumor cells.
Topics: Adenine; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Drug Synergism; Glutamine; Glycine; Hypoxanthines; Kinetics; Ligases; Methionine Sulfoximine; Nitrogen; Nucleotides; Pentosephosphates; Purines; Transferases | 1969 |
[Development kinetics of Rous sarcoma virus (Schmidt-Ruppin strain). Estimation of arginine incorporation time into viral proteins. Electron microscope autoradiographic study].
Topics: Arginine; Asparagine; Autoradiography; Avian Sarcoma Viruses; Glutamine; Glycine; Kinetics; Lysine; Microscopy, Electron; Tritium; Uridine; Valine; Viral Proteins | 1969 |
Assays of glutamine and its aminotransferase with the enol-borate of phenylpyruvate.
Topics: Age Factors; Animals; Asparagine; Boric Acids; Carcinoma, Hepatocellular; Cold Temperature; Drug Stability; Female; Fetus; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver Neoplasms; Liver Regeneration; Male; Mammary Neoplasms, Experimental; Mathematics; Methods; Neoplasms, Experimental; Organ Specificity; Phenylpyruvic Acids; Rats; Sex Factors; Solubility; Spectrophotometry; Time Factors; Transaminases; Ultraviolet Rays | 1970 |
A spectrophotometric method for the simultaneous measurement of L-glutamine and L-asparagine in biological materials.
Topics: Aminohydrolases; Ammonia; Animals; Arginine; Asparagine; Brain; Escherichia coli; Evaluation Studies as Topic; Glutamate Dehydrogenase; Glutamine; Hot Temperature; Humans; Ketoglutaric Acids; Liver; Methionine Sulfoximine; Methods; Mice; NAD; Peptide Hydrolases; Spectrophotometry; Time Factors; Trichloroacetic Acid | 1971 |
Fluorometric measurement of glutamine and asparagine using enzymic methods.
Topics: Adenine Nucleotides; Animals; Asparaginase; Asparagine; Aspartate Aminotransferases; Cerebral Cortex; Escherichia coli; Fluorometry; Glutamate Dehydrogenase; Glutaminase; Glutamine; Hydrolysis; Ketoglutaric Acids; Malate Dehydrogenase; Methods; NAD; Rats | 1971 |
The complete enzymic hydrolysis of horse muscle acyl phosphatase.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chemical Phenomena; Chemistry, Physical; Dipeptidases; Glutamine; Horses; Hydrolysis; Leucyl Aminopeptidase; Muscles; Papain; Phosphoric Monoester Hydrolases; Tryptophan | 1971 |
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotopes; Carcinoma, Hepatocellular; Chlorine; Glutamine; Kinetics; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mast Cells; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma 180 | 1972 |
The examination of the presence of amide groups in glutamic acid and aspartic acid residues of staphylococcal nuclease (Foggi strain).
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Asparagine; Aspartic Acid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glutamates; Glutamine; Molecular Weight; Peptides; Phosphoric Monoester Hydrolases; Staphylococcus; Thiocyanates; Trypsin | 1972 |
Revised amide location for porcine and human adrenocorticotropic hormone.
Topics: Adrenocorticotropic Hormone; Amides; Amino Acid Sequence; Animals; Asparagine; Chemical Phenomena; Chemistry; Electrophoresis, Disc; Glutamine; Humans; Swine | 1971 |
Sequence data: magnitude and implications of some ambiguities.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Biological Evolution; Cytochrome c Group; Fibrin; Glutamates; Glutamine; Hemoglobins; Horses; Mutation; Peptides; Plants; Swine | 1972 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
The physiology of the synthesis of amino acids and their movement into the seed proteins of plants.
Topics: Amino Acids; Asparagine; Carbon Isotopes; Edible Grain; Glutamine; NADP; Nitrogen; Photosynthesis; Plant Proteins; Seeds | 1970 |
Conversion of the alpha-hydroxy and alpha-keto analogues of methionine to methionine by cell-free extracts of adult female Ascaris suum.
Topics: Ascaris; Asparagine; Aspartic Acid; Butyrates; Cell-Free System; Female; Glutamates; Glutamine; Methionine; NAD; NADP; Oxidation-Reduction; Proteins | 1971 |
Amino acids as olfactory stimuli in freshwater catfish, Ictalurus catus (Linn.).
Topics: Alanine; Amino Acids; Animals; Asparagine; Cysteine; Fishes; Glutamine; Methionine; Olfactory Mucosa; Stereoisomerism | 1971 |
The primary sequence of badger myoglobin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Carnivora; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Chymotrypsin; Cyanogen Bromide; Dansyl Compounds; Electrophoresis, Paper; Glutamine; Myoglobin; Peptide Fragments; Protein Denaturation; Thermolysin; Trypsin | 1974 |
A modified lithium buffer system for analysis of acidic and neutral amino acids in physiological fluids.
Topics: Amino Acids; Asparagine; Blood Chemical Analysis; Body Fluids; Buffers; Citrates; Cystine; Glutamine; Humans; Hydrogen-Ion Concentration; Leucine; Lithium; Methods; Urine | 1974 |
Carbamyl phosphate and glutamine stimulation of the gallbladder salt pump.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Azaserine; Bicarbonates; Biological Transport, Active; Carbamates; Gallbladder; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; Organophosphorus Compounds; Rabbits; Sodium Chloride; Water | 1974 |
Utilization of amino acids as nitrogen sources, and their effects on nitrate reductase in the marine diatom Cyclotella cryptica.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Asparagine; Cell-Free System; Chlorophyll; Eukaryota; Glutamates; Glutamine; Glycine; Isoleucine; Nitrate Reductases; Nitrates; Ornithine; Plant Proteins; Proline; Seawater; Urea; Water Microbiology | 1974 |
[Amino acid composition of proteins of the placenta and the fetal membranes in abortion].
Topics: Abortion, Spontaneous; Asparagine; Cystine; Extraembryonic Membranes; Female; Glutamine; Histidine; Humans; Lysine; Placenta; Pregnancy; Proteins; Valine | 1974 |
Relationship between amino acid transport and electron transport by membrane vesicles of Micrococcus denitrificans.
Topics: Alanine; Amino Acids; Anaerobiosis; Asparagine; Biological Transport; Carbon Radioisotopes; Cell Membrane; Electron Transport; Glucose; Glutamine; Glycine; Kinetics; Lactates; Micrococcus; Muramidase; Nitrate Reductases; Oxygen Consumption; Paracoccus denitrificans; Succinates | 1974 |
[Studies of the chemically defined media for Pasteurella multocida and P. haemolytica].
Topics: Arginine; Asparagine; Cell Division; Culture Media; Cystine; Glucose; Glutamine; Hydrogen-Ion Concentration; Magnesium Sulfate; Nicotinic Acids; Orotic Acid; Pantothenic Acid; Pasteurella; Phosphates; Plant Growth Regulators; Serine; Sodium Chloride; Stereoisomerism | 1974 |
Further characterization of two co-lipases from porcine pancreas.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Electrophoresis, Disc; Glutamates; Glutamine; Hydrogen-Ion Concentration; Isoenzymes; Lipase; Molecular Weight; Pancreas; Swine | 1974 |
Determination of pH differences occurring during isotachophoresis with different systems of leading and terminating electrolytes.
Topics: Acetates; Asparagine; Buffers; Electrolytes; Electrophoresis; Formates; Glutamine; Glycine; Hydrogen-Ion Concentration; Methods; Tromethamine | 1973 |
Effect of asparagine and glutamine deficiency on normal and leukemic cells.
Topics: Animals; Asparagine; Carbon Radioisotopes; Cell Count; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Glutamine; Humans; Lectins; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocytes; Mice; Neoplasm Proteins | 1973 |
Evolution and the distribution of glutaminyl and asparaginyl residues in proteins.
Topics: Amides; Asparagine; Biological Clocks; Biological Evolution; Chemical Phenomena; Chemistry; Genetic Code; Glutamine; Kinetics; Peptides; Proteins; Time Factors | 1974 |
Reversal of the immunosuppressive effect of L-asparaginase by L-glutamine.
Topics: Animals; Antibody Formation; Asparaginase; Asparagine; Cells, Cultured; Erythrocytes; Glutamine; Hemolytic Plaque Technique; Immunization; Immunosuppressive Agents; Lectins; Lymphocyte Activation; Male; Mice; Sheep; Spleen | 1972 |
Metabolic activity of purified suspensions of Mycobacterium lepraemurium.
Topics: Acetates; Aerobiosis; Asparagine; Carbon Isotopes; Citric Acid Cycle; Culture Media; Fumarates; Glucose; Glutamine; Glycerol; Hydrogen-Ion Concentration; Ketoglutaric Acids; Mycobacterium lepraemurium; Succinates | 1972 |
Biosynthesis of melittin, a toxic peptide from bee venom. Amino-acid sequence of the precursor.
Topics: Alanine; Amides; Amino Acid Sequence; Animals; Asparagine; Bees; Carbon Isotopes; Cathepsins; Chromatography, Paper; Electrophoresis, Paper; Exocrine Glands; Glutamates; Glutamine; Glycine; Hydrolysis; Pepsin A; Peptides; Proline; Protein Precursors; Threonine; Tritium; Trypsin; Venoms | 1973 |
Interaction of Escherichia coli carbamyl phosphate synthetase with glutamine.
Topics: Adenosine Triphosphate; Amides; Amino Acids; Asparagine; Bicarbonates; Binding Sites; Carbamates; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Glutaminase; Glutamine; Keto Acids; Kinetics; Magnesium; Molecular Weight; Phosphotransferases; Protein Binding; Protein Denaturation; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship | 1973 |
Step-change versus gradient lithium buffers for single-column chromatography of complex amino acid mixtures.
Topics: Amino Acids; Asparagine; Buffers; Chromatography; Glutamine; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Lithium; Methods | 1973 |
Conversion of exposed aspartyl and glutamyl residues in proteins to asparaginyl and glutaminyl residues.
Topics: Amides; Ammonium Chloride; Animals; Asparaginase; Asparagine; Aspartic Acid; Autoanalysis; Carbodiimides; Cattle; Chymotrypsin; Chymotrypsinogen; Escherichia coli; Esters; Glutamates; Glutamine; Glycine; Muramidase; Pancreas; Pepsin A; Protein Conformation; Proteins; Ribonucleases; Spectrophotometry; Stomach; Swine; Trypsin | 1973 |
Effect of L-asparaginase on retention of maze learning in mice.
Topics: Animals; Asparaginase; Asparagine; Behavior, Animal; Escherichia coli; Glutamine; Injections, Intraperitoneal; Injections, Spinal; Male; Memory; Mice; Mice, Inbred BALB C; Time Factors | 1973 |
L-glutamine as a substrate for L-asparaginase from Serratia marcescens.
Topics: Ammonium Sulfate; Animals; Asparaginase; Asparagine; Chemical Precipitation; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Escherichia coli; Female; Glutaminase; Glutamine; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Mice; Mice, Inbred C3H; Serratia marcescens; Spectrophotometry; Stereoisomerism | 1974 |
Isoacceptor tRNAs for glutamate, glutamine, aspartate and asparagine in calf brain.
Topics: Animals; Asparagine; Aspartic Acid; Brain; Carbon Radioisotopes; Cattle; Chromatography; Chromatography, Gel; Escherichia coli; Glutamates; Glutamine; Humans; Liver; Liver Regeneration; Lymphocytes; Male; Mice; Neoplasms, Experimental; Organ Specificity; Plasmacytoma; Rats; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet | 1974 |
Asparagine utilization in Escherichia coli.
Topics: Ammonia; Anaerobiosis; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bacterial Proteins; Carbon Radioisotopes; Chromatography, Thin Layer; Culture Media; Cytoplasm; Densitometry; Escherichia coli; Glutamine; Mutation; Stereoisomerism; Valerates | 1974 |
Ammonia assimilation in blue-green algae.
Topics: Alanine; Amino Acid Oxidoreductases; Ammonia; Asparagine; Cell-Free System; Cyanobacteria; Glutamate Dehydrogenase; Glutamates; Glutamine; Ketoglutaric Acids; Nitrates; Nitrogen; Transaminases | 1973 |
Carboxyl group modification and amide assignments in automated sequencing of proteins.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Esters; Glutamates; Glutamine; Glycine; Hydrolysis; Imines; Methanol; Methods; Methylamines; Ribonucleases; Serine; Thiazoles | 1972 |
Metabolite activation and glycine accumulation in Ehrlich ascites tumor.
Topics: Acetates; Adenosine Triphosphate; Alanine; Animals; Ascites; Asparagine; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cycloheximide; Female; Fructose; Glucose; Glutamine; Glycine; Ketoglutaric Acids; Lactates; Linoleic Acids; Methods; Mice; Oxaloacetates; Puromycin; Pyruvates; Stimulation, Chemical; Succinates | 1972 |
Multiple resins for analysis of amino acids and ninhydrin-positive compounds in hydrolyzates and physiological fluids.
Topics: Amino Acids; Asparagine; Buffers; Chromatography, Ion Exchange; Citrates; Glutamine; Humans; Hydrolysis; Ion Exchange Resins; Lithium; Methods; Peptides; Time Factors | 1972 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
[Demonstration of tumor-induced amino acid changes in the extracellular fluid using two-way separation by high voltage electrophoresis followed by chromatography].
Topics: Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Chromatography; Cystine; Electrophoresis; Extracellular Space; Glutamates; Glutamine; Rats; Sarcoma, Yoshida; Serine; Threonine | 1972 |
Concentration of alpha-amino nitrogen and free amino acid in the uterine and blastocoelic fluid of rabbit.
Topics: Alanine; Amines; Amino Acids; Amniotic Fluid; Animals; Asparagine; Autoanalysis; Blastocyst; Castration; Chromatography, Paper; Embryo Implantation; Estrus; Female; Fertilization; Glutamates; Glutamine; Glycine; Nitrogen; Pregnancy; Pregnancy, Animal; Rabbits; Serine; Time Factors | 1972 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
[Free plasma amino acids in diabetes during acute hypoglycemia].
Topics: Acute Disease; Amino Acids; Asparagine; Diabetes Mellitus; Female; Glutamine; Humans; Hypoglycemia; Insulin; Male; Taurine | 1973 |
Incorporation of 14 C from (U- 14 C)glucose into free amino acids in mouse brain loci in vivo under normal conditions.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Autoradiography; Brain; Carbon Isotopes; Cerebral Cortex; Chromatography, Gas; Densitometry; Female; Glucose; Glutamates; Glutamine; Glycine; Hippocampus; Hypothalamus; Kinetics; Male; Mice; Thalamus | 1973 |
Comparative effect of intravenously administered nitrogenous compounds on uric acid synthesis in chickens fed a 20 per cent protein diet.
Topics: Acetates; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Chickens; Dietary Proteins; Glutamates; Glutamine; Glycine; Injections, Intravenous; Inosine; Lysine; Male; Nitrogen; Quaternary Ammonium Compounds; Sodium; Structure-Activity Relationship; Threonine; Time Factors; Uric Acid | 1973 |
Crayfish ventral nerve cord and hemolymph: content of free amino acids and other metabolites.
Topics: Amino Acids; Aminobutyrates; Ammonia; Animals; Asparagine; Astacoidea; Chromatography, Ion Exchange; Citrulline; Female; Glucose; Glutamates; Glutamine; Hemolymph; In Vitro Techniques; Male; Neurons; Sex Factors; Tryptophan; Urea | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
The free and bound amino acids removed by hemodialysis.
Topics: Adult; Alanine; Amino Acids; Asparagine; Aspartic Acid; Blood Flow Velocity; Blood Glucose; Body Weight; Cystine; Fasting; Female; Freeze Drying; Glucose; Glutamine; Glycine; Humans; Hydrolysis; Kidneys, Artificial; Male; Methionine; Middle Aged; Molecular Weight; Proline; Renal Dialysis; Uremia | 1973 |
Determination of asparagine, glutamine and pyrrolidonecarboxylic acid in total enzymic hydrolysates of peptides and glycopeptides by gas-liquid chromatography.
Topics: Amino Acids; Asparagine; Chromatography, Gas; Enzymes; Esters; Fluoroacetates; Glutamine; Glycopeptides; Homoserine; Hydrolysis; Hydroxylysine; Lysine; Methods; Peptides; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1973 |
Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of serine, threonine, aspartic and glutamic acids, asparagine, and glutamine.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Fourier Analysis; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Protons; Serine; Threonine; Time Factors | 1973 |
Influence of denervation on the free amino acids of the rat diaphragm.
Topics: Alanine; Amino Acids; Animals; Asparagine; Denervation; Diaphragm; Glutamine; Glycine; Liver Regeneration; Male; Rats; Serine; Taurine; Time Factors | 1973 |
Comparative effects of casein and amino acid mixture simulating casein on growth and food intake in rats.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartic Acid; Body Weight; Caseins; Diet; Dietary Proteins; Evaluation Studies as Topic; Feeding Behavior; Glutamates; Glutamine; Male; Metabolism; Nitrogen; Nutritional Requirements; Rats; Structure-Activity Relationship | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Rates of nonenzymatic deamidation of glutaminyl and asparaginyl residues in pentapeptides.
Topics: Asparagine; Buffers; Deamination; Glutamine; Hydrogen-Ion Concentration; Kinetics; Methods; Oligopeptides | 1973 |
Purification and properties of L-asparaginase A from Acinetobacter calcoaceticus.
Topics: Animals; Asparaginase; Asparagine; Bacteria; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamine; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Lymphoma; Macromolecular Substances; Magnesium; Mice; Molecular Weight; Sulfhydryl Reagents; Temperature; Ultracentrifugation | 1973 |
[Characteristics of asparaginase and glutaminase synthesis in Ps. boreopolis 526].
Topics: Asparaginase; Asparagine; Aspartic Acid; Glutamates; Glutaminase; Glutamine; Ligases; Pseudomonas | 1973 |
[Effect of some organic acids on the growth of Corynebacterium sepedonicum in the presence of asparagine and glutamine].
Topics: Asparagine; Carboxylic Acids; Citrates; Corynebacterium; Glutamine; Ketoglutaric Acids; Malates; Methionine; Oxaloacetates; Pyruvates; Succinates | 1973 |
Therapeutic properties of a new glutaminase-asparaginase preparation and the influence of the lactate dehydrogenase-elevating virus.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamates; Glutaminase; Glutamine; Half-Life; Hydrogen-Ion Concentration; Isoelectric Focusing; L-Lactate Dehydrogenase; Leukemia, Experimental; Mice; Mice, Inbred C57BL; RNA Viruses | 1974 |
Recovery of amino acids and tRNA after scintillation counting of radioactive aminoacyl-tRNA in filter paper strips.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartic Acid; Brain; Carbon Radioisotopes; Carbonates; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Evaluation Studies as Topic; Glutamates; Glutamine; Lysine; Male; Methionine; Methods; Paper; Quaternary Ammonium Compounds; RNA, Transfer; Time Factors | 1974 |
Hyperprolinemia type II.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amino Acid Metabolism, Inborn Errors; Amino Acids; Asparagine; Aspartate Aminotransferases; Blood Protein Electrophoresis; Body Height; Body Weight; Borohydrides; Child; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Paper; Creatinine; Electroencephalography; Female; Glutamine; Humans; Immunoglobulin A; Immunoglobulin G; L-Lactate Dehydrogenase; Male; Proline; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
L-Asparaginase production by the rumen anaerobe Vibrio succinogenes.
Topics: Anaerobiosis; Animals; Asparaginase; Asparagine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Culture Media; Electron Transport; Fumarates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Malates; Nitrates; Rumen; Stereoisomerism; Succinates; Vibrio | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and -resis
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Cell-Free System; Culture Techniques; Escherichia coli; Female; Glutamine; Leucine; Lymphoma; Male; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rabbits; Rats | 1968 |
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Cell Nucleus; Enzyme Repression; Escherichia coli; Feedback; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Leukemia; Ligases; Liver; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Microsomes; Mitochondria, Liver; Neoplasms, Experimental; Puromycin; Spleen; Stimulation, Chemical | 1968 |
Guinea pig asparagine synthetase.
Topics: Aluminum; Animals; Asparaginase; Asparagine; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Escherichia coli; Gels; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Intestine, Small; Ligases; Liver; Lymph Nodes; Male; Methods; Quaternary Ammonium Compounds; Spleen; Sulfates | 1969 |
Glutaminase activity of L-asparagine amidohydrolase.
Topics: Asparaginase; Asparagine; Azaserine; Carbon Isotopes; Escherichia coli; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine | 1969 |
L-asparaginase synthesis by Escherichia coli B.
Topics: Asparaginase; Asparagine; Aspartic Acid; Copper; Culture Media; Escherichia coli; Glucose; Glutamine; Glycerol; Iron; Manganese; Monosaccharides; Temperature; Zinc | 1969 |
Antineoplastic activity of highly purified bacterial glutaminases.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacteria; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Escherichia coli; Female; Glutaminase; Glutamine; Leucine; Mice; Neoplasm Proteins | 1970 |
Crystalline L-asparaginase from Escherichia coli B. I. Purification and chemical characterization.
Topics: Alcohols; Amino Acids; Asparaginase; Asparagine; Carbohydrates; Crystallization; Electrophoresis, Disc; Escherichia coli; Glutamine; Hydrogen-Ion Concentration; Magnesium; Methods; Molecular Weight; Phospholipids; Spectrophotometry; Ultracentrifugation; Ultraviolet Rays | 1970 |
[Studies of a Burkitt lymphoma].
Topics: Asparagine; Burkitt Lymphoma; Child, Preschool; Fluorescent Antibody Technique; Glutamine; Humans; Male | 1970 |
A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase.
Topics: Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Escherichia coli; Glutamates; Glutaminase; Glutamine; Ligases | 1970 |
Amino acids of the 6C3HED lymphosarcoma following treatment with asparaginase.
Topics: Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Female; Glutamates; Glutamine; Glycine; Liver; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Spleen | 1970 |
Peptidoglutaminase. Enzymes for selective deamidation of gamma-amide of peptide-bound glutamine.
Topics: Amides; Amino Acids; Amino Alcohols; Asparagine; Bacillus; Carbon Isotopes; Caseins; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis; Escherichia coli; Glutaminase; Glutamine; Glycine; Hydroxamic Acids; Hydroxyapatites; Methods; Paper; Peptide Hydrolases; Peptides; Phenylalanine; Soil Microbiology | 1971 |
Formaldehyde-induced cross-linkages in the subunit of the Escherichia coli tryptophan synthetase.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Formaldehyde; Glutamine; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Lysine; Molecular Weight; Paper; Pepsin A; Peptides; Serine; Trypsin; Tryptophan | 1971 |
[Effect of L-asparaginase from Escherichia coli on the phytohemagglutinin stimulated lymphocyte cultures].
Topics: Asparaginase; Asparagine; Aspartic Acid; Culture Techniques; Depression, Chemical; Escherichia coli; Glutamine; Humans; Lectins; Lymphocytes; Mitosis; Stimulation, Chemical; Time Factors | 1970 |
Studies on the glutaminase activity of E. coli asparaginase in tissue culture.
Topics: Asparaginase; Asparagine; Carbon Isotopes; Depression, Chemical; Drug Resistance; Eosinophils; Escherichia coli; Glutamates; Glutaminase; Glutamine; HeLa Cells; Humans; Leucine; Leukocytes; Lymphocyte Activation; Mitosis; Monocytes; Neutrophils; Stimulation, Chemical; Thymidine; Uridine | 1970 |
Studies of resistance to L-asparaginase in human leukemia.
Topics: Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Drug Resistance; Escherichia coli; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Ligases | 1970 |
Initiation of the germination of Bacillus subtilis spores by a combination of compounds in place of L-alanine.
Topics: Alanine; Amino Acids; Asparagine; Bacillus cereus; Bacillus subtilis; Buffers; Fructose; Glucose; Glutamine; Hydroxylamines; Potassium; Spores | 1968 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
Gamma-glutamyl phosphate attached to glutamine-specific tRNA. A precursor of glutaminyl-tRNA in Bacillus subtilis.
Topics: Adenosine Triphosphate; Amides; Asparagine; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Chromatography, Paper; Glutamates; Glutamine; Phosphoric Acids; Phosphorus Isotopes; Protein Biosynthesis; Ribonucleases; RNA, Bacterial; RNA, Transfer; Transferases; Tritium | 1969 |
Multiple transport components for dicarboxylic amino acids in Streptococcus faecalis.
Topics: Amino Acids; Aminoisobutyric Acids; Asparagine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cyclopentanes; Diffusion; Enterococcus faecalis; Glucose; Glutamates; Glutamine; Kinetics | 1970 |
Stability of methionine hydroxy analog in rumen fluid and its conversion in vitro to methionine by calf liver and kidney.
Topics: Aminobutyrates; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Biotransformation; Carbon Isotopes; Cattle; Chromatography, Thin Layer; Culture Techniques; Ethers; Female; Glutamine; Kidney; Leucine; Liver; Methionine; Microsomes; Microsomes, Liver; Rumen | 1972 |
Regional and subcellular distribution of aminotransferases in rat brain.
Topics: Alanine; Alanine Transaminase; Aminobutyrates; Animals; Asparagine; Aspartate Aminotransferases; Brain; Cerebral Cortex; Corpus Callosum; Glutamates; Glutamine; Glyoxylates; Ketoglutaric Acids; Male; Mesencephalon; Methionine; Ornithine; Oxaloacetates; Phenylalanine; Rats; Sciatic Nerve; Spinal Cord; Subcellular Fractions; Transaminases; Tyrosine | 1972 |
Glucagon structure and function. I. Purification and properties of bovine glucagon and monodesmidoglucagon.
Topics: Amino Acids; Animals; Asparagine; Biological Assay; Blood Glucose; Carboxypeptidases; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chymotrypsin; Circular Dichroism; Electrophoresis, Disc; Glucagon; Glutamine; Peptides; Protein Conformation; Rabbits; Radioimmunoassay; Swine; Ultraviolet Rays; Urea | 1972 |
On the relation of glutamic acid and some allied compounds to corticl spreading depression.
Topics: Action Potentials; Animals; Asparagine; Aspartic Acid; Cerebral Cortex; Cortical Spreading Depression; Glutamates; Glutamine; Hippocampus; Iontophoresis; Membrane Potentials; Rabbits; Rats | 1972 |
Enzymic assay of L-asparagine.
Topics: Asparaginase; Asparagine; Glutamate Dehydrogenase; Glutamine; Mathematics; Methods; Plants; Spectrophotometry; Ultraviolet Rays | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
Glutamine-dependent asparagine synthetase from leukemia cells. Chloride dependence, mechanism of action, and inhibition.
Topics: Amino Acids; Ammonium Sulfate; Animals; Asparagine; Aspartic Acid; Bromides; Carbon Isotopes; Catalysis; Chemical Precipitation; Chlorides; Chromatography, Gel; Electrophoresis, Disc; Enzyme Activation; Glutamine; Iodides; Keto Acids; Leukemia, Experimental; Ligases; Mice; Phosphorus Isotopes; Protein Binding; Quaternary Ammonium Compounds | 1972 |
Effects of L-asparaginase on lymphocyte surface and blastogenesis.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Binding Sites; Cell Membrane; Cell Survival; Cells, Cultured; Concanavalin A; DNA; Dose-Response Relationship, Drug; Glutamine; Immunity; Immunosuppressive Agents; Iodine Isotopes; Isoelectric Focusing; Lymphocyte Activation; Lymphocytes; Mitosis; Protein Binding; Rats; Receptors, Drug; Time Factors | 1972 |
Studies on the dansylation reaction by the use of 14 C-dansyl chloride: application to analysis of free amino acids in the rat optic nerve.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Autoanalysis; Autoradiography; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Thin Layer; Dansyl Compounds; Glucose; Glutamates; Glutamine; Glycine; Male; Methods; Optic Nerve; Rats; Tritium | 1972 |
The effect of L-asparaginase in mixed leukocyte culture.
Topics: Asparaginase; Asparagine; Aspartic Acid; Culture Techniques; Depression, Chemical; Glutamine; Humans; Leukocytes; Thymidine; Tritium | 1971 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
Analysis of the effects of arginine N-acetylasparaginate on the central nervous system.
Topics: Acetylcholine; Amygdala; Animals; Arginine; Asparagine; Cats; Caudate Nucleus; Cerebral Cortex; Depression, Chemical; Dipeptides; Electroencephalography; Evoked Potentials; Female; Glutamine; Male; Neural Pathways; Neurons, Efferent; Olivary Nucleus; Organ of Corti; Rabbits; Thiopental | 1971 |
A lithium buffer system for accelerated single-column amino acid analysis in physiological fluids.
Topics: Amino Acids; Amniotic Fluid; Animals; Asparagine; Autoanalysis; Buffers; Cattle; Chromatography, Ion Exchange; Citrates; Female; Glutamine; Hydrogen-Ion Concentration; Indicators and Reagents; Ion Exchange Resins; Lithium; Methods; Pregnancy; Sheep; Temperature | 1971 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Studies on the utilization of asparagine by mouse leukemia cells.
Topics: Amides; Ammonium Chloride; Animals; Asparagine; Carbon Isotopes; Culture Techniques; DNA, Neoplasm; Glutamine; Leukemia, Experimental; Mice; Neoplasm Proteins; Nitrogen Isotopes; Pentosyltransferases; RNA, Neoplasm | 1971 |
Studies on fruit tissues of Citrus acida. I. Utilization of protein for the respiration in mature fruit tissues of Citrus acida.
Topics: Adenosine Triphosphate; Alanine; Alanine Transaminase; Amides; Aminobutyrates; Ammonia; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Carboxy-Lyases; Citrus; Glutamate Dehydrogenase; Glutamates; Glutamine; Ligases; Oxygen Consumption; Peptide Hydrolases; Plant Development; Plant Proteins; Plants; Time Factors | 1971 |
Molecular orbital calculations on the conformation of polypeptides and proteins. 8. The conformational energy maps and stereochemical rotational states of the asparaginyl, glutaminyl aspartyl and glutamyl residues.
Topics: Amides; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glutamine; Mathematics; Molecular Weight; Peptides; Protein Conformation; Quantum Theory | 1971 |
2,4-dimethoxybenzyl as a protecting group for glutamine and asparagine in peptide synthesis.
Topics: Asparagine; Benzyl Compounds; Glutamine; Peptides | 1971 |
Uptake and incorporation of amino acids by the preimplantation mouse embryo.
Topics: Amino Acids; Animals; Asparagine; Carbon Isotopes; Culture Media; Embryo, Mammalian; Female; Fertilization; Glutamine; Leucine; Mice; Ovum | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
The in vitro translation of a monocistronic message.
Topics: Asparagine; Autoradiography; Cysteine; Electrophoresis; Escherichia coli; Genetic Code; Glutamine; In Vitro Techniques; Kinetics; Plant Viruses; RNA, Messenger; Tryptophan; Viral Proteins | 1965 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
[Electroencephalographic and biochemical changes induced by a drug(N-acetylasparaginate of arginine)facilitating various learning processes].
Topics: Acetylcholine; Animals; Arginine; Asparagine; Brain Chemistry; Catecholamines; Cats; Cerebral Cortex; Electroencephalography; Glutamine; Learning | 1969 |
A lithium buffer system for single-column amino acid analysis.
Topics: Amino Acids; Asparagine; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Glutamine; Hot Temperature; Indicators and Reagents; Lithium; Serine; Threonine | 1969 |
[Some data on the developmental mechanism of nephrotic edema].
Topics: Asparagine; Blood Proteins; Child; Child, Preschool; Edema; Female; Glutamine; Glycine; Humans; Male; Nephrotic Syndrome; Proteinuria | 1969 |
[Enzyme induction and metabolic regulation in mycobacteria. II. Utilization of glutamic acid and propionic acid in the proliferative phase of M. smegmatis].
Topics: Alanine; Amides; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Chromatography, Paper; Culture Media; Enzyme Induction; Enzyme Repression; Formamides; Glutamates; Glutamine; Glycerol; Mycobacterium; Oxygen Consumption; Propionates; Valine | 1969 |
[Seasonal changes in the activity of enzymes, desaminizing glutamine in the brain of Spermophilus].
Topics: Ammonia; Animals; Asparagine; Brain; Glutaminase; Glutamine; Rodentia; Seasons; Transaminases | 1969 |
The labeling of dicarboxylic amino acids and their amides by glucose and acetate in human platelets.
Topics: Amino Acids; Asparagine; Aspartic Acid; Biological Assay; Blood Platelets; Carbon Isotopes; Glutamates; Glutamine; Humans; Radiometry; Uranium | 1970 |
Mechanisms of heat damage in proteins. 2. Chemical changes in pure proteins.
Topics: Albumins; Ammonia; Asparagine; Chemical Phenomena; Chemistry; Cystine; Glutamine; Hot Temperature; Isoleucine; Lysine; Protein Denaturation; Serum Albumin, Bovine; Sulfides | 1970 |
Accumulation of 2-aminoimidazole by Streptomyces eurocidicus.
Topics: Amines; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Asparagine; Chromatography, Paper; Creatine; Creatinine; Glucose; Glutamine; Glycine; Histidine; Imidazoles; Nucleosides; Spectrophotometry; Streptomyces | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
The primary structure of porcine pancreatic ribonuclease. II. The amino acid sequence of the reduced S-aminoethylated protein.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Animals; Asparagine; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cyanides; Cysteine; Glutamine; Glycoproteins; Kinetics; Oxidation-Reduction; Pancreatic Juice; Papain; Peptides; Polysaccharides; Rats; Ribonucleases; Species Specificity; Spectrophotometry; Swine; Trypsin | 1970 |
Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and gamma-glutamyl transfer.
Topics: Acyltransferases; Alanine; Amino Acids; Animals; Asparagine; Brain; Chemical Phenomena; Chemistry; Formates; Glutamine; Glycine; Kinetics; Ligases; Liver; Lysine; Phenylalanine; Rats; Sheep; Tyrosine | 1970 |
Protein-bound amide groups in brain.
Topics: Amides; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Glucose; Glutamates; Glutamine; Hydrochloric Acid; Nerve Tissue Proteins; Pentobarbital; Peptide Hydrolases; Picrotoxin; Protein Binding; Rats; Seizures; Streptomyces | 1970 |
[The qualitative and quantitative demonstration of free amino acids in tonsil tissue with the use of paper chromatography].
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Asparagine; Child; Child, Preschool; Chromatography, Paper; Glutamine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Methods; Middle Aged; Palatine Tonsil; Phenylalanine; Valine | 1970 |
Acid protease from germinated sorghum. 2. Substrate specificity with synthetic peptides and ribonuclease A.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Endopeptidases; Formates; Glutamates; Glutamine; Methylation; Peptides; Peroxides; Plants; Ribonucleases | 1970 |
The covalent structure of a human gamma G-immunoglobulin. IX. Assignment of asparaginyl and glutaminyl residues.
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Asparagine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Electrophoresis; Endopeptidases; Glutamine; Humans; Immunoglobulin G; Immunoglobulins; Leucyl Aminopeptidase; Peptide Hydrolases | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
Accelerated amino acid analysis: studies on the use of lithium citrate buffers and the effect of n-propanol, in the analysis of physiological fluids and protein hydrolyzates.
Topics: 1-Propanol; Amino Acids; Asparagine; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Glutamine; Hydrogen-Ion Concentration; Lithium; Methods; Protein Hydrolysates; Time Factors | 1970 |
Benzyl and p-nitrobenzyl monoesters of N-t-butyloxycarbonyl-L-glutamic acid and N-t-butyloxycarbonyl-L-aspartic acid.
Topics: Amines; Asparagine; Aspartic Acid; Cyclohexanes; Dimethylformamide; Esters; Furans; Glutamates; Glutamine; Nitrobenzenes | 1970 |
Asparagine biosynthesis in human KB tumor cells: inhibitor studies with asparagine and glutamine antagonists.
Topics: Amino Acids; Anti-Bacterial Agents; Asparagine; Aspartic Acid; Azaserine; Azo Compounds; Carcinoma; Cell Line; Culture Techniques; Glutamine; Humans; Ligases; Mouth Neoplasms; Puromycin | 1970 |
[Amino acid composition of calf skin proteins and radiation effects].
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Proteins; Radiation Effects; Serine; Skin | 1970 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium | 1970 |
The interaction of protein with single strands of DNA and RNA.
Topics: Amino Acid Sequence; Asparagine; DNA; Glutamine; Models, Chemical; Proteins; Purines; Pyrimidines; RNA | 1970 |
With reference to blastogenesis inhibition by L-asparaginase.
Topics: Asparaginase; Asparagine; Aspartic Acid; Cells, Cultured; Depression, Chemical; Glutamine; Humans; Lectins; Lymphocyte Activation; Time Factors | 1970 |
[Effect of substrate supply on post-asphyctic restoration of adenine nucleotides in rabbit hearts in vivo].
Topics: Adenine; Adenine Nucleotides; Animals; Asparagine; Asphyxia; Creatine; Folic Acid; Formates; Fructose; Glucose; Glutamine; Glycine; Glycogen; Heart; Isotonic Solutions; Lactates; Methods; Myocardium; Nucleosides; Oxalates; Phosphates; Phosphocreatine; Rabbits; Ribose | 1970 |
Amide groups of some tryptic peptides from the beta-chain of horse hemoglobin.
Topics: Amides; Amino Acid Sequence; Amino Acids; Animals; Asparagine; Chromatography, Ion Exchange; Electrophoresis; Glutamine; Hemoglobins; Horses; Papain; Peptides; Trypsin | 1970 |
Metabolism of asparagine, aspartate, glutamine, and glutamate in lymphoid tissue: basis for immunosuppression by L-asparaginase.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Carbon Isotopes; Dogs; Glutamates; Glutamine; Humans; Immunity; Immunosuppression Therapy; Ligases; Lymph Nodes; Lymphoid Tissue; Mice; Spleen | 1971 |
Rabbit hemoglobin. The heterogeneity of the beta-chain.
Topics: Acetates; Alleles; Amino Acids; Animals; Asparagine; Chromatography, Ion Exchange; Formates; Glutamine; Hemoglobins; Heterozygote; Histidine; Homozygote; Peptides; Pyridines; Rabbits; Serine | 1971 |
Glutamyl, aspartyl and amide moieties of cerebral proteins: metabolic aspects in vitro.
Topics: Amides; Ammonia; Ammonium Chloride; Animals; Asparaginase; Asparagine; Aspartic Acid; Autoradiography; Carbon Isotopes; Carboxy-Lyases; Cats; Cerebral Cortex; Glutamates; Glutaminase; Glutamine; Hydrolases; Hydrolysis; In Vitro Techniques; Mass Spectrometry; Nerve Tissue Proteins; Nitrogen Isotopes; Protein Binding | 1971 |
Activation of amino acids in the brain during experimental allergic encephalomyelitis.
Topics: Amino Acids; Animals; Asparagine; Brain Chemistry; Cerebral Cortex; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamates; Glutamine; Ligases; Male; Phenylalanine; Rabbits; Tissue Extracts | 1971 |
New methods in peptide synthesis. V. On alpha- and gamma-diphenylmethyl and phenacyl esters of L-glutamic acid.
Topics: Asparagine; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Glutamine; Peptides; Proline | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The reaction of asparagine, glutamine, and derivatives with phosgene.
Topics: Asparagine; Chemical Phenomena; Chemistry; Dioxins; Glutamine; Nitriles; Phosgene | 1968 |
Multiple forms of cytochrome c in the rat. Precursor-product relationship between the main component Cy I and the minor components Cy II and Cy 3 in vivo.
Topics: Animals; Asparagine; Cattle; Chromatography, Gel; Cytochromes; DNA; Electron Transport; Electrophoresis, Disc; Female; Glutamine; Iron Isotopes; Kidney; Liver; Myocardium; Rats; Time Factors | 1968 |
Column chromatographic analysis of neutral and acidic amino acids using lithium buffers.
Topics: Adipates; Amino Acids; Aminobutyrates; Asparagine; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrulline; Fasting; Glutamine; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Lithium; Methods; Proline; Spectrophotometry; Time Factors | 1968 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
[On the question of biosynthesis of 2 acetyl-2 decarboxamidooxytetracycline by the culture Act. rimosus].
Topics: Actinomyces; Ammonia; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Oxytetracycline; Streptomyces; Sulfates; Time Factors; Urea | 1968 |
[Derivatives of asparagine and glutamine with 2,4-dimethoxy-benzyl- and 2,4,6-trimethoxybenzyl protected amide groups].
Topics: Amides; Asparagine; Glutamine; Methods; Peptides | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
[Conditioning of avoidance learning, labyrinth learning and operant behavior under the influence of central stimulation].
Topics: Animals; Arginine; Asparagine; Avoidance Learning; Behavior, Animal; Central Nervous System; Conditioning, Psychological; Glutamine; Learning; Male; Methylphenidate; Rats; Stimulation, Chemical | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
[The nitrogen metabolism of mycobacteria].
Topics: Amino Acids; Asparagine; Glutamates; Glutamine; Glycerol; Mycobacterium; Nicotinic Acids; Nitrogen; Oxygen Consumption | 1968 |
Amino acid levels following L-asparagine amidohydrolase (EC.3.5.1.1) therapy.
Topics: Amidohydrolases; Amino Acids; Asparaginase; Asparagine; Female; Glutamates; Glutamine; Humans; Male; Neoplasms | 1969 |
Amino acids, including asparagine and glutamine, in plasma and urine of normal human subjects.
Topics: Adult; Amino Acids; Asparagine; Autoanalysis; Buffers; Chromatography; Citrates; Creatinine; Female; Glutamine; Humans; Lithium; Male; Methods; Spectrophotometry; Tryptophan | 1969 |
Human platelets: amino acid synthesis.
Topics: Acetates; Asparagine; Aspartic Acid; Blood Platelets; Carbon Isotopes; Citric Acid Cycle; Coenzyme A; Glucose; Glutamates; Glutamine; Humans | 1969 |
Metabolic traits in mentally retarded children as compared with normal populations: monoaminodicarboxylic acids and their half amides and total amino acids.
Topics: Adolescent; Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Child; Child, Preschool; Chromatography; Chromatography, Paper; Female; Glutamates; Glutamine; Glycine; Humans; Intellectual Disability; Male | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Partial purification and properties of carbamoyl phosphate synthetase of Alaska pea (Pisum sativum L. cultivar Alaska).
Topics: Adenosine Triphosphate; Asparagine; Carbamates; Chromatography, Gel; Glutamine; Iron; Magnesium; Manganese; Ornithine; Phosphotransferases; Plants; Potassium; Quaternary Ammonium Compounds; Urea | 1969 |
Free amino acids of normal and abnormal human placenta.
Topics: Amino Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Female; Glutamine; Humans; Hydatidiform Mole; Infarction; Ligases; Placenta; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications | 1969 |
The optical resolution of DL-aspartic acid, DL-glutamic acid, DL-asparagine and DL-glutamine by preferential crystallization.
Topics: Asparagine; Chemistry Techniques, Analytical; Crystallization; Glutamates; Glutamine | 1965 |
Total optical resolution of free alpha-amino-acids by the inoculation method.
Topics: Asparagine; Aspartic Acid; Crystallization; Glutamates; Glutamine | 1965 |
Separation of glutamine and asparagine by ion exchange chromatography with temperature programming.
Topics: Adult; Aged; Asparagine; Blood; Chromatography, Ion Exchange; Female; Glutamine; Humans; Infant; Male; Middle Aged | 1965 |
[On the identification of the C-terminal residues of a protein after hydrazinolysis].
Topics: Amino Acid Sequence; Asparagine; Chromatography; Glutamine; Hydrazines; Protein Hydrolysates | 1964 |
L-Glutamine as donor of carbamoyl group nitrogen for the enzymic synthesis of citrulline in green pea seedlings.
Topics: Asparagine; Citrulline; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Magnesium; Nitrogen; Plants; Quaternary Ammonium Compounds; Sulfhydryl Compounds | 1965 |
Dietary requirement for asparagine and its metabolism in rats.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Dioxide; Caseins; Diet; Glutamine; Protein Hydrolysates; Rats | 1966 |
Kinetic studies on the action of carboxypeptidase A on bovine insulin and related model peptides.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Kinetics; Models, Theoretical; Peptides; Spectrophotometry | 1966 |
Determination of free ammonium and asparagine and glutamine amide-nitrogen in extracts of plant tissue.
Topics: Amides; Ammonia; Asparagine; Glutamine; Nitrogen; Plants | 1966 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Active copper transport in mammalian tissues--a possible role in Wilson's disease.
Topics: Animals; Asparagine; Carcinoma, Ehrlich Tumor; Copper; Glutamine; Hepatolenticular Degeneration; Histidine; In Vitro Techniques; Kidney; Liver; Radioisotopes; Rats; Threonine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
The conversion of [3H]tyrosine to [3H]DOPA in mouse melanoma in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Chromatography, Paper; Dihydroxyphenylalanine; Electrophoresis; Glutamates; Glutamine; Melanoma; Mice; Neoplasms, Experimental; Tyrosine | 1966 |
Synthesis and pharmacological activity of 4-d-glutamine-oxytocin, 5-d-asparagine-oxytocin, and 4-d-glutamine-5-d-asparagine-oxytocin.
Topics: Animals; Asparagine; Blood Pressure; Chemistry, Organic; Drug Synergism; Female; Glutamine; Organic Chemistry Phenomena; Oxytocin; Poultry; Rats; Uterus | 1966 |
A method for estimating free asparagine and glutamine in biological fluids as trinitrophenyl derivatives.
Topics: Animals; Asparagine; Chemical Precipitation; Chromatography; Glutamine; Horses; Mice; Nitrophenols; Tissue Extracts | 1966 |
Solubility-composition relations of gluten proteins.
Topics: Asparagine; Glutamine; Glutens; Solubility | 1966 |
Transglutaminase activity of the fibrin crosslinking enzyme.
Topics: Acyltransferases; Asparagine; Chromatography, Ion Exchange; Dipeptides; Fibrin; Glutamine; Glycine; Sulfites | 1966 |
Amino acids and the maintenance of osmotic equilibrium in brain tissue.
Topics: Alanine; Amino Acids; Amino Alcohols; Aminobutyrates; Animals; Anura; Asparagine; Aspartic Acid; Brain Chemistry; Female; Glutamates; Glutamine; Glycine; Male; Osmosis; Urea | 1966 |
Deuterated amino acids. 3. Synthesis of DL-Aspartic-2,3,3-d-3 acid, L-glutamic-2,3,3,4,4-d-5 acid, L-asparagine-2,3,3-d-3, and L-Glutamine-2,3,3,4,4-d-5 1,2a.
Topics: Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Chemistry, Organic; Deuterium; Glutamates; Glutamine; Organic Chemistry Phenomena | 1966 |
[The influence of temperature on the content of some carbohydrates and amino acids in Spirogyra].
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, Paper; Eukaryota; Fructose; Glucose; Glutamates; Glutamine; Leucine; Nitrogen; Serine; Starch; Temperature; Valine | 1966 |
[Study of the conditions of biosynthesis of 2-acetyl-2-decarboxyamidooxytetracycline by the culture of Act. rimosus].
Topics: Asparagine; Culture Media; Fermentation; Glutamine; Hybridization, Genetic; Oxytetracycline; Phosphorus; Streptomyces | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
The state of copper in human serum: evidence for an amino acid-bound fraction.
Topics: Amino Acids; Asparagine; Biological Transport; Ceruloplasmin; Copper; Glutamine; Histidine; Humans; Radioisotopes; Serum Albumin; Threonine | 1967 |
Reactions in frozen systems. VI. Ice as a possible model for biological structured-water systems.
Topics: Acetylcholine; Asparagine; Catalysis; Chemical Phenomena; Chemistry; Copper; Cytosine; Dioxins; Glutamates; Glutamine; Glycine; Hydroxylamines; Ice; Imidazoles; Kinetics; Models, Theoretical; Nitrates; Phenylalanine; Piperazines; Potassium Chloride; Pyrazoles; Serine; Tyrosine | 1967 |
The influence of medium composition on the growth and swarming of Proteus.
Topics: Alanine; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Proline; Proteus; Serine | 1967 |
Effects of L-asparagine and related compounds on the hepatic fatty infiltration and necrosis induced by ethionine and carbon tetrachloride.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Tetrachloride; Chromatography, Gas; Ethionine; Fatty Acids; Fatty Liver; Female; Glutamine; Glycerides; Ketoglutaric Acids; Liver; Methionine; Necrosis; Rats; Triglycerides | 1967 |
A paper chromatographic method for identification and estimation of pyrrolidonecarboxylic acid.
Topics: Asparagine; Chemical Phenomena; Chemistry; Chlorides; Chromatography, Paper; Glutamates; Glutamine; Glutathione; Humans; Hydroxylamines; Iron; Methanol; Pyrrolidinones; Trichloroacetic Acid | 1967 |
Regulation of glutamine synthetase. VI. Interactions of inhibitors for Bacillus licheniformis glutamine synthetase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Ammonium Chloride; Asparagine; Aspartic Acid; Bacillus; Carbamates; Drug Antagonism; Drug Synergism; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydroxamic Acids; Isoleucine; Kinetics; Ligases | 1967 |
Intrinsic dissociation constants of aspartyl and glutamyl carboxyl groups.
Topics: Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Hydrogen-Ion Concentration | 1967 |
L-asparagine biosynthesis by nutritional variants of the Jensen sarcoma.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; Culture Techniques; Electrophoresis; Glutamine; Ligases; Magnesium; Sarcoma, Experimental | 1967 |
Glutamine metabolism of isolated rat hepatocytes. Evidence for catecholamine activation of alpha-ketoglutarate dehydrogenase.
Topics: Acyl Coenzyme A; Ammonium Chloride; Animals; Asparagine; Bucladesine; Enzyme Activation; Glutamine; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Liver; Male; Norepinephrine; Ornithine; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1984 |
Effect of asparagine, glutamine and insulin on cerebral amino acid neurotransmitters.
Topics: Animals; Asparagine; Aspartic Acid; Brain Chemistry; Cerebellum; Friedreich Ataxia; gamma-Aminobutyric Acid; Glutamates; Glutamine; Insulin; Male; Medulla Oblongata; Neurotransmitter Agents; Rats | 1980 |
Huntington's disease. Glutamate and aspartate metabolism in blood platelets.
Topics: Adult; Asparagine; Aspartic Acid; Blood Platelets; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Huntington Disease; Kinetics; Male; Middle Aged | 1982 |
Asparagine synthetases of Klebsiella aerogenes: properties and regulation of synthesis.
Topics: Ammonia; Asparagine; Aspartate-Ammonia Ligase; Genes; Genes, Bacterial; Glutamine; Kinetics; Klebsiella pneumoniae; Ligases; Molecular Weight; Mutation | 1982 |
Purification and properties of glutamine synthetase from the plant cytosol fraction of lupin nodules.
Topics: Amino Acids; Asparagine; Cytosol; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Molecular Weight; Plants | 1982 |
Successful long-term use of a plasmapheresis reactor system in dogs with lymphoma.
Topics: Animals; Asparagine; Dog Diseases; Dogs; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lymphoma; Plasmapheresis | 1983 |
A high-performance liquid chromatography assay for asparagine synthetase.
Topics: Amino Acids; Animals; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Glutamates; Glutamine; Ligases; o-Phthalaldehyde; Pancreas; Pyridoxal | 1984 |
Formation and properties of L-glutaminase and L-asparaginase activities in Pichia polymorpha.
Topics: Ascomycota; Asparaginase; Asparagine; Cations, Divalent; Enzyme Induction; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Pichia; Substrate Specificity; Temperature | 1980 |
Comparison of system N in fetal hepatocytes and in related cell lines.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lithium; Liver; Liver Neoplasms; Sodium | 1983 |
Asparagine and glutamine metabolism in chicks.
Topics: Amino Acids; Ammonium Chloride; Animals; Asparaginase; Asparagine; Bicarbonates; Chickens; Dietary Proteins; Glutaminase; Glutamine; Kidney; Liver; Mitochondria; Mitochondria, Liver; Sodium Bicarbonate | 1984 |
Inhibition of blastogenesis by native and polyethylene glycol-modified asparaginases from Escherichia coli and Vibrio succinogenes.
Topics: Animals; Asparaginase; Asparagine; Cells, Cultured; Escherichia coli; Glutaminase; Glutamine; Immunosuppressive Agents; Lymphocyte Activation; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Vibrio | 1983 |
The stimulus-secretion coupling of amino acid-induced insulin release. Inhibition of islet respiration and insulin release by aminooxyacetate.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Animals; Asparagine; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Oxygen Consumption; Rats | 1984 |
A minimum essential medium for cultivation of Schistosoma japonicum eggs.
Topics: Amino Acids; Animals; Asparagine; Culture Media; Female; Glutamine; Ovum; Parasitology; Schistosoma japonicum | 1983 |
Glucagon and insulin release in the lamb before and after birth: effects of amino acids in vitro and in vivo.
Topics: Amino Acids; Animals; Asparagine; Glucagon; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Sheep | 1982 |
Effects of branched-chain L-amino acids, L-phenylalanine, and L-methionine on the transport of L-glutamine in rat brain cortex in vitro. Influence of cations.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Asparagine; Biological Transport; Calcium; Cations; Cerebral Cortex; Egtazic Acid; Glutamine; In Vitro Techniques; Kinetics; Male; Methionine; Phenylalanine; Potassium; Rats | 1980 |
Kainic acid selectively stimulates the release of endogenous excitatory acidic amino acids.
Topics: Amino Acids; Animals; Asparagine; Brain Chemistry; Calcium; Cerebellum; Corpus Striatum; Glutamine; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred Strains; Neurotoxins; Pyrrolidines; Rats; Rats, Inbred Strains; Tetrodotoxin | 1983 |
Determination of asparagine and glutamine in polypeptides using bis(I,I-trifluoroacetoxy)iodobenzene.
Topics: Actins; Amino Acids; Asparagine; Chymotrypsinogen; Glutamine; Guanidines; Hydrolysis; Insulin; Iodobenzenes; Peptides; Ribonucleases | 1981 |
Pleiotropic deficiency in nitrogen-uptake systems and derepression of nitrogen-catabolic enzymes in npr-1 mutants of Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Acidic; Ammonia; Asparagine; Carbon-Nitrogen Ligases; Gene Expression Regulation; Glutamine; Ligases; Membrane Transport Proteins; Mutation; Nitrogen; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1982 |
Plasma and erythrocyte amino acid levels in normal adult subjects fed a high protein meal with and without added monosodium glutamate.
Topics: Adult; Alanine; Amino Acids; Asparagine; Aspartic Acid; Dietary Proteins; Erythrocytes; Female; Glutamates; Glutamine; Humans; Male; Sodium Glutamate | 1982 |
Practical gas-liquid chromatographic method for the determination of amino acids in human serum.
Topics: Amino Acids; Arginine; Asparagine; Chromatography, Gas; Formates; Formic Acid Esters; Glutamine; Humans; Isoleucine; Leucine; Tyrosine | 1982 |
Asparagine and glutamine metabolism in Rhodopseudomonas acidophila.
Topics: Asparaginase; Asparagine; Glutaminase; Glutamine; Glycine; Glyoxylates; Methionine Sulfoximine; Rhodopseudomonas; Transaminases | 1980 |
Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.
Topics: Amidohydrolases; Animals; Asparagine; Azo Compounds; Cell Line; Diazooxonorleucine; DNA; Glutamine; Glycine; Isoxazoles; Kinetics; Leukemia L1210; Mice; Oxazoles; Temperature | 1981 |
Nitrogen utilization in mice bearing Ehrlich ascites tumor treated with Acinetobacter glutaminase-asparaginase.
Topics: Acinetobacter; Amidohydrolases; Animals; Asparagine; Body Weight; Bone and Bones; Carcinoma, Ehrlich Tumor; Diet; Dietary Proteins; Energy Metabolism; Female; Glutamine; Liver; Mice; Nitrogen; Prognosis | 1981 |
Effects of amino acid analogues on protein degradation in isolated rat hepatocytes.
Topics: Amino Acids; Animals; Asparagine; Autophagy; Glutamine; Histidine; Leucine; Liver; Male; Phenylalanine; Proteins; Rats; Structure-Activity Relationship; Tryptophan | 1981 |
Conversion of alpha-ketobutyrate to alpha-amino-n-butyric acid by isolated rat liver cells: effect of ethanol.
Topics: Aminobutyrates; Animals; Asparagine; Aspartic Acid; Butyrates; Ethanol; Female; Glutamates; Glutamine; In Vitro Techniques; Liver; Rats; Rats, Inbred Strains | 1981 |
Enzyme therapy of cancer, future studies.
Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice | 1981 |
Influence of individual amino acids on incorporation of [14C]leucine by rat liver ribosomes.
Topics: Amino Acids; Amino Acids, Essential; Animals; Asparagine; Aspartic Acid; Glutamates; Glutamine; Leucine; Liver; Rats; Ribosomal Proteins; Ribosomes | 1980 |
Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.
Topics: Amino Acids; Animals; Asparagine; Biological Transport; Cells, Cultured; Choline; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lithium; Liver; Male; Rats; Sodium; Structure-Activity Relationship | 1980 |
Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Asparagine; Autophagy; Drug Synergism; Glutamine; Liver; Lysosomes; Male; Phagocytosis; Proteins; Rats; Transaminases | 1980 |
Fate of [G-3H]glutamate and [U-14C]glucose in the rat liver in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Glucose; Glutamates; Glutamine; Glutathione; Kinetics; Liver; Male; Proteins; Rats | 1980 |
The role of lipid metabolism in neoplastic differentiation.
Topics: Animals; Asparagine; Cell Transformation, Neoplastic; Cholesterol; Citric Acid Cycle; Feedback; Glucose; Glutamine; Humans; Lipids; Models, Biological; Neoplasms, Experimental; Nitrogen; Oxygen Consumption; Polyamines | 1980 |
Glutamate, glutamine, aspartate, asparagine, glucose and ketone-body metabolism in chick intestinal brush-border cells.
Topics: Adenine Nucleotides; Amino Acids, Dicarboxylic; Animals; Asparagine; Aspartic Acid; Chickens; Glucose; Glutamates; Glutamine; Glutathione; In Vitro Techniques; Jejunum; Ketone Bodies; Male; Microvilli; Oxygen Consumption; Rats | 1980 |
The application of hydrogen bonding analysis in X-ray crystallography to help orientate asparagine, glutamine and histidine side chains.
Topics: Algorithms; Asparagine; Computer Simulation; Crystallography, X-Ray; Databases, Factual; Glutamine; Histidine; Hydrogen Bonding; Models, Molecular; Protein Conformation | 1995 |
L-glutamine and L-asparagine stimulate ODC activity and proliferation in a porcine jejunal enterocyte line.
Topics: Aminooxyacetic Acid; Animals; Asparagine; Cell Division; Cell Line; Drug Synergism; Eflornithine; Enzyme Activation; Glutamine; Jejunum; Ornithine Decarboxylase; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sodium-Hydrogen Exchangers; Swine; Thymidine; Transaminases | 1995 |
Genetic evidence for Gln3p-independent, nitrogen catabolite repression-sensitive gene expression in Saccharomyces cerevisiae.
Topics: Asparagine; Base Sequence; DNA-Binding Proteins; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; Glutamine; Glutathione Peroxidase; Molecular Sequence Data; Mutation; Nitrogen; Prions; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors | 1995 |
Molecular study of the 5 alpha-reductase type 2 gene in three European families with 5 alpha-reductase deficiency.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adolescent; Amino Acid Sequence; Arginine; Asparagine; Base Sequence; Disorders of Sex Development; Exons; Female; France; Glutamine; Histidine; Humans; Introns; Male; Molecular Sequence Data; Open Reading Frames; Point Mutation; Poland; Serine | 1995 |
Structural determinants of protein dynamics: analysis of 15N NMR relaxation measurements for main-chain and side-chain nuclei of hen egg white lysozyme.
Topics: Amino Acid Sequence; Animals; Asparagine; Chickens; Crystallography, X-Ray; Female; Glutamine; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Nitrogen Isotopes; Protein Structure, Secondary; Recombinant Fusion Proteins; Recombinant Proteins; Thermodynamics | 1995 |
Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity.
Topics: Animals; Asparagine; Catalysis; Cell Line; Glutamine; Histidine; Humans; Mutagenesis, Site-Directed; Nucleopolyhedroviruses; Procollagen-Proline Dioxygenase; Serine; Spodoptera | 1995 |
Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway.
Topics: Acyltransferases; Amidohydrolases; Amino Acid Sequence; Amino Acids; Aminoacyltransferases; Asparagine; Aspartic Acid; Base Sequence; Carbohydrate Sequence; Cloning, Molecular; Codon; Fungal Proteins; Genes, Fungal; Glutamic Acid; Glutamine; Half-Life; Ligases; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Promoter Regions, Genetic; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligases | 1995 |
Expression in Escherichia coli of a gene encoding a thermostable chitinase from Streptomyces thermoviolaceus OPC-520.
Topics: Amino Acid Sequence; Asparagine; Catalysis; Chitinases; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Gene Expression Regulation, Bacterial; Glutamine; Hot Temperature; Molecular Sequence Data; Mutation; Plasmids; Promoter Regions, Genetic; Reference Standards; Streptomyces | 1995 |
Hydrogen bonding motifs of protein side chains: descriptions of binding of arginine and amide groups.
Topics: Adenine; Amides; Arginine; Asparagine; Glutamine; Guanine; Protein Binding; Protein Conformation; Proteins; Urea | 1995 |
Post-transcriptional regulation of nitrate reductase by light is abolished by an N-terminal deletion.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Asparagine; Base Sequence; Conserved Sequence; Darkness; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Genetic Complementation Test; Glutamine; Homozygote; Light; Molecular Sequence Data; Nicotiana; Nitrate Reductase; Nitrate Reductases; Peptides; Phosphorylation; Plants, Genetically Modified; Plants, Toxic; Protein Processing, Post-Translational; RNA Processing, Post-Transcriptional; RNA, Plant; Sequence Deletion; Sequence Homology, Amino Acid; Yeasts | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Tracing 15N with chemical reaction interface mass spectrometry: a demonstration using 15N-labeled glutamine and asparagine substrates in cell culture.
Topics: Asparagine; Carcinoma, Hepatocellular; Culture Media; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Liver Neoplasms; Nitrogen Isotopes; Tumor Cells, Cultured | 1994 |
Inhibition of cultured leukemia cell growth by enhanced adriamycin cytotoxicity with reduction of glutamine or asparagine level in medium.
Topics: Animals; Asparagine; Cell Division; Culture Media; Doxorubicin; Glutamine; Humans; Leukemia P388; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proline; Tumor Cells, Cultured | 1994 |
In vitro mutagenesis of growth hormone receptor Asn-linked glycosylation sites.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Binding, Competitive; Cross-Linking Reagents; Gene Expression; Glutamine; Glycosylation; L Cells; Mice; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Receptors, Somatotropin; Structure-Activity Relationship | 1994 |
Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cell Line; Glutamates; Glutamic Acid; Glutamine; Kinetics; Light; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Time Factors; Transfection | 1993 |
Effects of glutamine deprivation on glutamine transport and synthesis in primary culture of rat skeletal muscle.
Topics: Amino Acids; Animals; Animals, Newborn; Asparagine; Biological Transport; Cell Differentiation; Cell Division; Cells, Cultured; Cycloheximide; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Histidine; Insulin; Kinetics; Methionine Sulfoximine; Muscles; Rats; Time Factors; Tritium | 1993 |
Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B. Searching for the catalytic triad.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartate-Ammonia Ligase; Base Sequence; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Glutamine; Humans; Kinetics; Molecular Sequence Data; Nitrogen; Oligodeoxyribonucleotides; Recombinant Proteins; Sequence Homology, Amino Acid | 1994 |
Three new mutations of thyroid hormone receptor-beta associated with resistance to thyroid hormone.
Topics: Adolescent; Adult; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Drug Resistance; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Lysine; Male; Molecular Sequence Data; Point Mutation; Receptors, Thyroid Hormone; Sicily; Syndrome; Thyroid Hormones | 1994 |
Short-term starvation alters the free amino acid content of the human intestinal mucosa.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Asparagine; Colon; Duodenum; Food; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Intestinal Mucosa; Intestine, Large; Male; Starvation; Threonine; Time Factors | 1994 |
The role of two conserved amino acids, glutamine 90 and asparagine 137, in O6-methylguanine-DNA methyltransferase stability, activity and substrate specificity.
Topics: Asparagine; Binding Sites; DNA; DNA Repair; Enzyme Stability; Glutamine; Guanine; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity | 1994 |
Arginine 30 and asparagine 74 have functional roles in the glutamine dependent activities of Escherichia coli asparagine synthetase B.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Ammonia; Arginine; Asparagine; Aspartate-Ammonia Ligase; Base Sequence; Catalysis; Escherichia coli; Glutamine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen; Nucleotides; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transaminases | 1994 |
Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.
Topics: Acetylation; Amino Acids; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutamates; Glutamine; Humans; Lysine; Mass Spectrometry; Regression Analysis; Serine | 1994 |
Taurine, amino acid transmitters, and related molecules in the retina of the Australian lungfish Neoceratodus forsteri: a light-microscopic immunocytochemical and electron-microscopic study.
Topics: Animals; Arginine; Asparagine; Fishes; gamma-Aminobutyric Acid; Ganglia, Sensory; Glutamic Acid; Glutamine; Immunohistochemistry; Microglia; Microscopy, Electron; Neurotransmitter Agents; Nitric Oxide; Photoreceptor Cells; Retina; Taurine | 1994 |
NMR studies of recombinant Coprinus peroxidase and three site-directed mutants. Implications for peroxidase substrate binding.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Coprinus; Glutamine; Heme; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peroxidase; Phenylalanine; Recombinant Proteins; Substrate Specificity | 1994 |
Purification, crystallization and preliminary X-ray analysis of murine interleukin-5.
Topics: Animals; Asparagine; Baculoviridae; Crystallization; Crystallography, X-Ray; Glutamine; Interleukin-5; Isoelectric Point; Mice; Mutagenesis, Site-Directed; X-Ray Diffraction | 1994 |
Cis- and trans-acting elements involved in amino acid regulation of asparagine synthetase gene expression.
Topics: Amino Acids; Animals; Asparagine; Aspartate-Ammonia Ligase; Base Sequence; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Cricetinae; DNA; Exons; Gene Expression Regulation, Enzymologic; Glutamine; HeLa Cells; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Sequence Deletion; Sequence Homology, Nucleic Acid; Transfection | 1993 |
Subunit-specific block of cloned NMDA receptors by argiotoxin636.
Topics: Amino Acid Sequence; Animals; Asparagine; Cloning, Molecular; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Indoleacetic Acids; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylacetates; Polyamines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spider Venoms; Xenopus laevis | 1993 |
L-glutamine and L-asparagine stimulate Na+ -H+ exchange in porcine jejunal enterocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid-Base Equilibrium; Amiloride; Ammonium Chloride; Animals; Asparagine; Cell Line; Epithelium; Fluoresceins; Fluorescent Dyes; Glutamine; Hydrogen-Ion Concentration; Isoquinolines; Jejunum; Kinetics; Mannitol; Meglumine; Piperazines; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Swine; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Identification of alpha-carboxamidated and carboxy-terminal glycine forms of peptides in bovine hypothalamus, bovine pituitary and porcine heart extracts.
Topics: Acetylation; Amides; Amino Acid Sequence; Animals; Asparagine; Cattle; Chromatography, High Pressure Liquid; Glutamine; Glycine; Hypothalamus; Mass Spectrometry; Molecular Sequence Data; Myocardium; Oxidation-Reduction; Peptides; Pituitary Gland, Anterior; Swine; Thiohydantoins | 1993 |
Mutational analysis of the NH2-terminal glycosylation sites of the insulin receptor alpha-subunit.
Topics: 3T3 Cells; Animals; Asparagine; Binding Sites; Cell Membrane; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA Mutational Analysis; Glutamine; Glycosylation; Humans; Insulin; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphorylation; Receptor, Insulin; Restriction Mapping; Trypsin | 1994 |
Planar stacking interactions of arginine and aromatic side-chains in proteins.
Topics: Amino Acids; Arginine; Asparagine; Glutamine; Protein Conformation; Proteins | 1994 |
Glutamine transport in human skeletal muscle.
Topics: Asparagine; Biological Transport; Culture Media; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Ions; Kinetics; Membrane Potentials; Muscle Proteins; Muscles; Osmolar Concentration; Sarcolemma; Sodium; Substrate Specificity | 1993 |
Specific glycosylation site mutations of the insulin receptor alpha subunit impair intracellular transport.
Topics: 3T3 Cells; Animals; Asparagine; Biological Transport; DNA; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glutamine; Glycosylation; Humans; Insulin; Mice; Mutagenesis, Site-Directed; Peptide Mapping; Receptor, Insulin; Transfection | 1993 |
Characterization of the active site and thermostability regions of endoxylanase from Thermoanaerobacterium saccharolyticum B6A-RI.
Topics: Amino Acid Sequence; Asparagine; Bacteria, Anaerobic; Base Sequence; Binding Sites; Catalysis; Cloning, Molecular; DNA, Bacterial; Endo-1,4-beta Xylanases; Enzyme Stability; Glutamine; Glycoside Hydrolases; Molecular Sequence Data; Restriction Mapping; Sequence Homology, Amino Acid | 1993 |
Decoupling of photo- and proton cycle in the Asp85-->Glu mutant of bacteriorhodopsin.
Topics: Asparagine; Bacteriorhodopsins; Glutamine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protons | 1993 |
Regulatory circuit for responses of nitrogen catabolic gene expression to the GLN3 and DAL80 proteins and nitrogen catabolite repression in Saccharomyces cerevisiae.
Topics: Allantoin; Asparagine; Base Sequence; DNA-Binding Proteins; Fungal Proteins; gamma-Aminobutyric Acid; GATA Transcription Factors; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Glutamine; Models, Genetic; Molecular Sequence Data; Nitrogen; Proline; Regulatory Sequences, Nucleic Acid; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 1993 |
Inhibition of glycolysis by amino acids in ascites tumor cells. Specificity and mechanism.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Asparagine; Carcinoma, Ehrlich Tumor; Fructosediphosphates; Glucose; Glutamine; Glycolysis; Kinetics; Lactates; Male; Mice; Phosphofructokinase-1; Tumor Cells, Cultured | 1993 |
Effect of tunicamycin treatment on ligand binding to the erythropoietin receptor: conversion from two classes of binding sites to a single class.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Cell Line; Cricetinae; Erythropoietin; Glutamine; Glycosylation; Kidney; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, Erythropoietin; Recombinant Proteins; Tunicamycin | 1993 |
Common ring motifs in proteins involving asparagine or glutamine amide groups hydrogen-bonded to main-chain atoms.
Topics: Amides; Asparagine; Glutamine; Hydrogen Bonding; Protein Conformation; X-Ray Diffraction | 1993 |
Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells.
Topics: Adipose Tissue; Animals; Asparagine; Base Sequence; Cell Line; Cell Membrane; Chlorocebus aethiops; DNA Primers; Electroporation; Epididymis; Epitopes; Gene Expression; Glucose Transporter Type 4; Glutamine; Glycosylation; Insulin; Male; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Rats; Recombinant Proteins; RNA, Messenger; Transfection | 1996 |
Changes in intracellular concentration of amino acids in human saphenous vein during preparation for coronary artery bypass grafting.
Topics: Adenosine Triphosphate; Amino Acids; Asparagine; Biological Transport; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Glutamic Acid; Glutamine; Humans; Intracellular Fluid; Saphenous Vein; Taurine | 1995 |
Mobilization of glutamine and asparagine in mouse kidney during Ehrlich cell carcinoma development.
Topics: Animals; Asparagine; Carcinoma; Carcinoma, Ehrlich Tumor; Glutamine; Kidney; Mice | 1996 |
Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs.
Topics: Alkylation; Antineoplastic Agents; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Bacterial Proteins; Binding Sites; Drug Design; Enzyme Inhibitors; Escherichia coli; Glutamine; Humans; Isoenzymes; Kinetics; Molecular Conformation; Molecular Structure; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 1996 |
Assignment of aliphatic side-chain 1HN/15N resonances in perdeuterated proteins.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Deuterium; Glutamine; Guanidine; Guanidines; Humans; Hydrogen; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteins; Sensitivity and Specificity | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Protection of asparagine and glutamine during N alpha-Bpoc-based solid-phase peptide synthesis.
Topics: Asparagine; Biphenyl Compounds; Glutamine; Magnetic Resonance Spectroscopy; Molecular Structure; Oligopeptides | 1996 |
tRNA-dependent asparagine formation.
Topics: Acylation; Asparagine; Glutamine; Halobacteriaceae; RNA, Transfer; RNA, Transfer, Asn; RNA, Transfer, Gln | 1996 |
Storage of pure proteins.
Topics: Asparagine; Bacterial Physiological Phenomena; Drug Contamination; Drug Storage; Endopeptidases; Glutamine; Hydrogen-Ion Concentration; Kinetics; Ligands; Oxidation-Reduction; Protein Denaturation; Proteins; Reducing Agents; Salts; Temperature | 1996 |
A glutamate/glutamine/aspartate/asparagine transport operon in Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Asparagine; Aspartic Acid; Biological Transport; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Glutamic Acid; Glutamine; Molecular Sequence Data; Operon; Rhodobacter capsulatus; Sequence Homology, Amino Acid | 1996 |
Neurotransmitter amino acids in cerebrospinal fluid of patients with Parkinson's disease.
Topics: Aged; Amino Acids; Asparagine; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Parkinson Disease | 1996 |
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
Substrate binding mechanism of Glu180-->Gln, Asp176-->Asn, and wild-type glucoamylases from Aspergillus niger.
Topics: Asparagine; Aspartic Acid; Aspergillus niger; Glucan 1,4-alpha-Glucosidase; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Point Mutation; Protein Binding; Thermodynamics | 1996 |
Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Catalysis; Conserved Sequence; DNA; DNA Topoisomerases, Type I; Glutamine; Histidine; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Vaccinia virus | 1997 |
Isolation and characterization of Rhizobium etli mutants altered in degradation of asparagine.
Topics: Asparaginase; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Cloning, Molecular; Enzyme Stability; Genes, Bacterial; Genetic Complementation Test; Glutamic Acid; Glutamine; Isoenzymes; Mutation; Nitrogenase; Rhizobium; Temperature | 1997 |
Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides. Implications for motor activity.
Topics: Amino Acid Sequence; Asparagine; Chromatography, Gel; Circular Dichroism; Glutamine; Humans; Kinesins; Lasers; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Scattering, Radiation; Structure-Activity Relationship; Tyrosine | 1997 |
NCR-sensitive transport gene expression in S. cerevisiae is controlled by a branched regulatory pathway consisting of multiple NCR-responsive activator proteins.
Topics: Amino Acid Transport Systems; Asparagine; Blotting, Northern; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Glutamine; Glutathione Peroxidase; Membrane Transport Proteins; Nitrogen Compounds; Prions; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators; Transcription Factors; Transcription, Genetic | 1996 |
PMR1, a Ca2+-ATPase in yeast Golgi, has properties distinct from sarco/endoplasmic reticulum and plasma membrane calcium pumps.
Topics: Adenosine Triphosphate; Asparagine; Aspartic Acid; Calcium; Calcium-Transporting ATPases; Cell Membrane; Endoplasmic Reticulum; Enzyme Inhibitors; Evolution, Molecular; Glutamine; Golgi Apparatus; Heat-Shock Proteins; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Sarcoplasmic Reticulum | 1997 |
Mutagenesis and chemical rescue indicate residues involved in beta-aspartyl-AMP formation by Escherichia coli asparagine synthetase B.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Arginine; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Escherichia coli; Glutamine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Sequence Alignment; Software; Structure-Activity Relationship; Threonine | 1997 |
Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser/Thr sequons that are poor oligosaccharide acceptors.
Topics: Amino Acids; Antigens, Viral; Asparagine; Binding Sites; Glutamine; Glycoproteins; Glycosylation; Mutagenesis, Site-Directed; Oligosaccharides; Rabies virus; Serine; Structure-Activity Relationship; Threonine; Viral Envelope Proteins | 1997 |
Effect of individual carbohydrate chains of recombinant antithrombin on heparin affinity and on the generation of glycoforms differing in heparin affinity.
Topics: Animals; Antithrombin III; Asparagine; Binding Sites; Cell Line; Cricetinae; Glutamine; Glycosylation; Heparin; Humans; Kinetics; Mesocricetus; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Processing, Post-Translational; Recombinant Fusion Proteins | 1997 |
Ca2+ binding to the first epidermal growth factor module of coagulation factor VIIa is important for cofactor interaction and proteolytic function.
Topics: 1-Carboxyglutamic Acid; Alanine; Animals; Asparagine; Binding Sites; Calcium; CHO Cells; Cricetinae; Epidermal Growth Factor; Factor IX; Factor VIIa; Factor X; Glutamine; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Structure-Activity Relationship | 1997 |
Effect of polar side chains at position 172 on thermal stability of 3-isopropylmalate dehydrogenase from Thermus thermophilus.
Topics: 3-Isopropylmalate Dehydrogenase; Alanine; Alcohol Oxidoreductases; Asparagine; Enzyme Stability; Glutamic Acid; Glutamine; Heating; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Thermus thermophilus | 1997 |
Which amino-acids do serum and hemofiltrate of critically ill patients with acute renal failure contain?
Topics: Alanine; Amino Acids; Asparagine; Citrulline; Cystathionine; Ethanolamines; Extracorporeal Circulation; Glutamine; Glycine; Hemofiltration; Histidine; Humans; Kidney Failure, Chronic; Lactic Acid; Methionine; Proline | 1997 |
Glutamine homologues and derivatives: a limiting factor in current artificial nutrition?
Topics: Arginine; Asparagine; Aspartic Acid; Evaluation Studies as Topic; Glutamic Acid; Glutamine; Humans; Oxaloacetates; Parenteral Nutrition, Total | 1997 |
Amino acid utilisation and deamination of glutamine and asparagine by Helicobacter pylori.
Topics: Amino Acids; Ammonia; Asparaginase; Asparagine; Culture Media; Diazooxonorleucine; Enzyme Inhibitors; Glutaminase; Glutamine; Helicobacter pylori | 1997 |
Hydrogen bonding interactions between glutamine and asparagine in alpha-helical peptides.
Topics: Asparagine; Circular Dichroism; Computer Simulation; Crystallography; Databases, Factual; Glutamine; Hydrogen Bonding; Models, Theoretical; Peptides; Protein Structure, Secondary; Proteins | 1997 |
Evaluation of the role of specific acidic amino acid residues in electron transfer between the flavodoxin and cytochrome c3 from Desulfovibrio vulgaris.
Topics: Amino Acids, Dicarboxylic; Asparagine; Aspartic Acid; Cytochrome c Group; Desulfovibrio vulgaris; Electrochemistry; Electron Transport; Flavodoxin; Gene Expression Regulation, Bacterial; Glutamic Acid; Glutamine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration | 1997 |
The Gln223Arg and Lys656Asn polymorphisms in the human leptin receptor do not associate with traits related to obesity.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Asparagine; Blood Glucose; Body Constitution; Body Mass Index; Carrier Proteins; Female; Glutamine; Heterozygote; Homozygote; Humans; Insulin; Lysine; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Leptin; Reference Values; Socioeconomic Factors | 1997 |
Structure-function relationships in helix-bundle channels probed via total chemical synthesis of alamethicin dimers: effects of a Gln7 to Asn7 mutation.
Topics: Alamethicin; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Dimerization; Electric Conductivity; Glutamine; Ion Channels; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Structure, Secondary; Structure-Activity Relationship | 1997 |
Picosecond to hour time scale dynamics of a "three finger" toxin: correlation with its toxic and antigenic properties.
Topics: Animals; Anisotropy; Antibodies; Asparagine; Binding Sites; Cobra Neurotoxin Proteins; Deuterium; Disulfides; Epitopes; Glutamine; Kinetics; Models, Molecular; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Software | 1997 |
H2NCO-E.COSY, a simple method for the sterospecific assignment of side-chain amide protons in proteins.
Topics: Asparagine; Carbon Isotopes; Deuterium; Flavodoxin; Glutamine; Nuclear Magnetic Resonance, Biomolecular; Proteins | 1997 |
The influence of a scalar-coupled deuterium upon the relaxaton of a 15N Nucleus and its possible exploitation as a probe for side-chain interactions in proteins.
Topics: Asparagine; Deuterium; Epidermal Growth Factor; Fibronectins; Glutamine; Hydrogen Bonding; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Proteins; Recombinant Proteins; Tissue Plasminogen Activator | 1997 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine | 1997 |
Dissecting histidine interactions of ribonuclease T1 with asparagine and glutamine replacements: analysis of double mutant cycles at one position.
Topics: Amino Acid Substitution; Asparagine; Crystallography, X-Ray; Esterification; Exoribonucleases; Glutamine; Histidine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation | 1998 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Glutamine; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Ligands; Lysine; Mutagenesis, Site-Directed; Polymerase Chain Reaction | 1998 |
The Saccharomyces cerevisiae YCC5 (YCL025c) gene encodes an amino acid permease, Agp1, which transports asparagine and glutamine.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Amino Acids, Dicarboxylic; Ammonia; Asparagine; Biological Transport; Gene Expression Regulation, Fungal; Genes, Fungal; Glutamine; Kinetics; Membrane Transport Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1998 |
Involvement of glutamic acid 278 in the redox reaction of the cytochrome c oxidase from Paracoccus denitrificans investigated by FTIR spectroscopy.
Topics: Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport Complex IV; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Paracoccus denitrificans; Serine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 1998 |
Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Cattle; Glutamic Acid; Glutamine; Histidine; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Protein Structure, Secondary; Rhodopsin; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transducin | 1998 |
The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Deoxyuracil Nucleotides; Folic Acid; Glutamic Acid; Glutamine; Lacticaseibacillus casei; Mutation; Nucleotides; Protein Binding; Protein Conformation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Thymidylate Synthase | 1998 |
Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis.
Topics: Asparagine; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallization; Crystallography, X-Ray; Dimerization; Escherichia coli; Glutamine; Histidine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed | 1998 |
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Fungal Proteins; Glutamine; Kinetics; Molecular Sequence Data; Peptide Termination Factors; Peptides; Point Mutation; Prions; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Suppression, Genetic | 1998 |
Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Substitution; Animals; Arginine; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Citrate (si)-Synthase; Citric Acid; Enzyme Stability; Glutamine; Glycine; Histidine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxaloacetates; Protons; Solvents; Substrate Specificity; Swine | 1998 |
Glu78, from the conserved PEWY sequence of subunit IV, has a key function in cytochrome b6f turnover.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Transformation, Genetic | 1998 |
Determination of the in vivo deamidation rate of asparagine-101 from alpha-A crystallin using microdissected sections of the aging human lens.
Topics: Adolescent; Adult; Aging; Amides; Asparagine; Child; Child, Preschool; Crystallins; Dissection; Glutamine; Half-Life; Humans; Lens, Crystalline | 1998 |
Kinetic mechanism of Escherichia coli asparagine synthetase B.
Topics: Adenosine Monophosphate; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Bacterial Proteins; Binding, Competitive; Escherichia coli; Glutamine; Isotope Labeling; Kinetics; Oxygen Isotopes; Substrate Specificity | 1998 |
Membrane cofactor protein: importance of N- and O-glycosylation for complement regulatory function.
Topics: Animals; Antigens, CD; Asparagine; Cell Fractionation; CHO Cells; Clone Cells; Complement Activation; Complement C3b; Complement C4b; Cricetinae; Cytoprotection; Glutamine; Glycosylation; Humans; Hydrolysis; Kinetics; Membrane Cofactor Protein; Membrane Glycoproteins; Mutagenesis, Site-Directed; Proline; Protein Structure, Tertiary; Sequence Deletion; Serine; Threonine; Transfection | 1998 |
Transient kinetics of formation and reaction of the uridylyl-enzyme form of galactose-1-P uridylyltransferase and its Q168R-variant: insight into the molecular basis of galactosemia.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Enzyme Stability; Escherichia coli; Galactosemias; Glutamine; Humans; Iron; Kinetics; Mutagenesis, Site-Directed; Thermodynamics; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Zinc | 1998 |
Use of site-directed mutagenesis to identify residues specific for each reaction catalyzed by chorismate mutase-prephenate dehydrogenase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Chorismate Mutase; Circular Dichroism; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Prephenate Dehydrogenase; Recombinant Proteins | 1998 |
Asparagine and glutamine rotamers: B-factor cutoff and correction of amide flips yield distinct clustering.
Topics: Asparagine; Glutamine; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Structure, Secondary; Proteins | 1999 |
Calcium binding to the class I alpha-1,2-mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif.
Topics: Asparagine; Aspartic Acid; Binding Sites; Calcium; Calcium-Binding Proteins; Catalysis; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Kinetics; Mannosidases; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Saccharomyces cerevisiae | 1999 |
Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation.
Topics: Algorithms; Amides; Asparagine; Crystallography, X-Ray; Databases, Factual; Glutamine; Hydrogen; Models, Molecular; Protein Conformation; Proteins; Software; Static Electricity | 1999 |
Is glutamine a pretender to the throne?
Topics: Arginine; Asparagine; Aspartic Acid; Dipeptides; Glutamic Acid; Glutamine; Humans; Parenteral Nutrition, Total | 1999 |
Thiamin-binding protein from sunflower seeds.
Topics: Asparagine; Aspartic Acid; Carrier Proteins; Chromatography, Gel; Glutamic Acid; Glutamine; Helianthus; Hydrogen-Ion Concentration; Molecular Weight; Seeds; Thiamine | 1998 |
Evaluation of the role of His447 in the reaction catalyzed by cholesterol oxidase.
Topics: Asparagine; Binding Sites; Catalysis; Cholestenones; Cholesterol; Cholesterol Oxidase; Crystallography, X-Ray; Deuterium; Glutamine; Histidine; Hydrogen; Mutagenesis, Insertional; Oxidation-Reduction; Protein Isoforms; Solvents; Substrate Specificity | 1998 |
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity.
Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1998 |
Transfers of N metabolites across the ovine liver in response to short-term infusions of an amino acid mixture into the mesenteric vein.
Topics: Amino Acids; Ammonia; Animals; Asparagine; Glutamine; Hepatic Artery; Infusions, Intravenous; Liver; Male; Mesenteric Veins; Nitrogen; Portal Vein; Regional Blood Flow; Sheep; Urea | 1998 |
A K319N/E325Q double mutant of the lactose permease cotransports H+ with lactose. Implications for a proposed mechanism of H+/lactose symport.
Topics: Alanine; Amino Acid Substitution; Asparagine; Biological Transport; Codon; Escherichia coli; Escherichia coli Proteins; Glutamine; Hydrogen; Kinetics; Lactose; Lysine; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Symporters | 1999 |
Blood levels of ammonia and nitrogen scavenging amino acids in patients with inherited hyperammonemia.
Topics: Adolescent; Adult; Alanine; Amino Acids; Ammonia; Asparagine; Carbon-Nitrogen Ligases; Child; Child, Preschool; Data Interpretation, Statistical; Female; Glutamine; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Retrospective Studies | 1999 |
The contribution of acidic residues to the conformational stability of common-type acylphosphatase.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Amino Acid Substitution; Asparagine; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins; Substrate Specificity | 1999 |
H-bonding maintains the active site of type 1 copper proteins: site-directed mutagenesis of Asn38 in poplar plastocyanin.
Topics: Asparagine; Binding Sites; Glutamine; Hydrogen Bonding; Leucine; Mutagenesis, Site-Directed; Plastocyanin; Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Threonine; Trees | 1999 |
Hydrogen bonds between short polar side chains and peptide backbone: prevalence in proteins and effects on helix-forming propensities.
Topics: Asparagine; Aspartic Acid; Glutamine; Hydrogen Bonding; Kinetics; Protein Structure, Secondary; Serine; Threonine | 1999 |
Deamidation of alpha-A crystallin from nuclei of cataractous and normal human lenses.
Topics: Aged; Amides; Amino Acid Sequence; Asparagine; Cataract; Chromatography; Crystallins; Glutamine; Humans; Lens, Crystalline; Middle Aged | 1999 |
Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Topics: Asparagine; Binding Sites; Cholesterol Oxidase; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Glutamic Acid; Glutamine; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Streptomyces; Structure-Activity Relationship; Substrate Specificity; Water | 1999 |
Active sites of diacylglycerol kinase from Escherichia coli are shared between subunits.
Topics: Alanine; Asparagine; Aspartic Acid; Binding Sites; Circular Dichroism; Diacylglycerol Kinase; Enzyme Activation; Escherichia coli; Genetic Complementation Test; Glutamine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Serine; Structure-Activity Relationship | 1999 |
Measurement of urinary amino acids using high-performance liquid chromatography equipped with a strong cation exchange resin pre-column.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Humans; Reproducibility of Results | 1999 |
Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Biological Transport; Brain; Citric Acid Cycle; Glutamic Acid; Glutamine; Ketoglutaric Acids; Kinetics; Malates; Mitochondria; Rats; Rats, Wistar; Succinic Acid | 1999 |
Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein.
Topics: Amino Acid Substitution; Animals; Asparagine; Binding Sites; Carrier Proteins; CHO Cells; Cholesterol; Cricetinae; Endosomes; Glutamine; Glycosylation; Humans; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Leucine Zippers; Lysosomes; Membrane Glycoproteins; Molecular Weight; Mutagenesis, Site-Directed; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Phenotype; Point Mutation; Proteins; Recombinant Proteins; Sterols; Transfection | 1999 |
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Topics: Acylation; Anti-Bacterial Agents; Asparagine; Aspartic Acid; beta-Lactamases; beta-Lactams; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Glutamine; Kinetics; Models, Molecular; Mutation; Protein Conformation; Staphylococcus aureus; Structure-Activity Relationship | 1999 |
Influence of carbon and nitrogen sources on Flavobacteriumgrowth and zeaxanthin biosynthesis.
Topics: Ammonia; Asparagine; beta Carotene; Carbon; Flavobacterium; Glucose; Glutamine; Nitrogen; Oxaloacetic Acid; Pyruvic Acid; Sucrose; Xanthophylls; Zeaxanthins | 1999 |
Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.
Topics: Animals; Asparagine; Cell Membrane; COS Cells; Factor V; Factor Va; Glutamine; Glycoside Hydrolases; Glycosylation; Humans; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Thromboplastin; Transfection | 1999 |
Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Deuterium Oxide; DNA Glycosylases; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Solvents; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 1999 |
Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.
Topics: Ammonia; Asparagine; Crosses, Genetic; Fungal Proteins; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Glutamine; Glutathione Peroxidase; Nitrogen; Plasmids; Prions; Proline; Recombinant Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 1999 |
Intersegment hydrogen bonds as possible structural determinants of the N/Q/R site in glutamate receptors.
Topics: Arginine; Asparagine; Aspartic Acid; Binding Sites; Calcium; Excitatory Amino Acid Antagonists; Glutamine; Hydrogen Bonding; Kinetics; Models, Molecular; Monte Carlo Method; Oxygen; Protein Conformation; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Static Electricity | 1999 |
Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase.
Topics: Aggrecans; Alanine; Animals; Asparagine; Cattle; Cloning, Molecular; Endopeptidases; Extracellular Matrix Proteins; Glutamine; Humans; Lectins, C-Type; Matrix Metalloproteinases; Metalloendopeptidases; Phenylalanine; Protein Conformation; Proteoglycans; Recombinant Proteins; Substrate Specificity | 1999 |
Glutamate-containing parenteral nutrition doubles plasma glutamate: a risk factor in neurosurgical patients with blood-brain barrier damage?
Topics: Asparagine; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Chromatography, High Pressure Liquid; Craniotomy; Female; Glutamic Acid; Glutamine; Hospitals, University; Humans; Intensive Care Units; Male; Middle Aged; Parenteral Nutrition; Prospective Studies; Risk Factors; Treatment Outcome | 1999 |
Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase.
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Catalytic Domain; Computer Simulation; Formycins; Glutamine; Kinetics; Lysine; Mice; Models, Molecular; Purine-Nucleoside Phosphorylase; Substrate Specificity | 1999 |
The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Topics: Apoenzymes; Asparagine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamine; Histidine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Serine; Stereoisomerism | 1999 |
Mutant trimers of light-harvesting complex II exhibit altered pigment content and spectroscopic features.
Topics: Asparagine; Binding Sites; Carotenoids; Chlorophyll; Glutamic Acid; Glutamine; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Pisum sativum; Protein Folding; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Functional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domain.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; CHO Cells; Cricetinae; Glutamine; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Nociceptin Receptor; Phenylalanine; Protein Conformation; Receptors, Opioid; Signal Transduction; Tryptophan; Tyrosine | 2000 |
Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis.
Topics: Asparagine; Base Sequence; Binding Sites; Deoxyguanine Nucleotides; Dideoxynucleosides; Drug Resistance, Microbial; Glutamine; HIV Reverse Transcriptase; Humans; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; RNA, Viral; Substrate Specificity; Templates, Genetic | 2000 |
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions.
Topics: Adipose Tissue, Brown; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Chlorides; Cricetinae; Electron Transport; Glutamic Acid; Glutamine; Guanosine Triphosphate; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1 | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Probing the CD lumenal loop region of the D2 protein of photosystem II in Synechocystis sp. strain PCC 6803 by combinatorial mutagenesis.
Topics: Alanine; Asparagine; Base Sequence; Cyanobacteria; DNA, Bacterial; Glutamine; Glycine; Molecular Sequence Data; Mutagenesis; Phenylalanine; Photosynthetic Reaction Center Complex Proteins | 2000 |
Human lens beta-crystallin solubility.
Topics: Aged; Asparagine; Chromatography, High Pressure Liquid; Crystallins; Glutamine; Glutathione; Humans; Lens Capsule, Crystalline; Mass Spectrometry; Models, Chemical; Molecular Weight; Peptide Mapping; Solubility; Solutions | 2000 |
Functional analysis of the C-terminal region of recombinant human thrombopoietin. C-terminal region of thrombopoietin is a "shuttle" peptide to help secretion.
Topics: Animals; Asparagine; Blotting, Western; COS Cells; Enzyme-Linked Immunosorbent Assay; Glutamine; Glycosylation; Humans; Mutagenesis, Site-Directed; Recombinant Proteins; Structure-Activity Relationship; Thrombopoietin | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Modeling the effects of mutations on the free energy of the first electron transfer from QA- to QB in photosynthetic reaction centers.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Electron Transport; Energy Transfer; Glutamic Acid; Glutamine; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter capsulatus; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Water | 2000 |
Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.
Topics: Amino Acid Transport Systems, Neutral; Animals; Asparagine; Carrier Proteins; Cell Line; Exons; Female; Gene Library; Glutamine; Humans; Introns; Liver; Membrane Potentials; Membrane Transport Proteins; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Protons; Rats; Sequence Analysis, DNA; Sodium; Species Specificity; Substrate Specificity; Xenopus laevis | 2000 |
Selective methylation changes on the Bacillus subtilis chemotaxis receptor McpB promote adaptation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus subtilis; Bacterial Proteins; Chemoreceptor Cells; Consensus Sequence; Genotype; Glutamic Acid; Glutamine; Membrane Proteins; Methanol; Methylation; Models, Biological; Mutagenesis, Site-Directed; Recombinant Proteins; Static Electricity | 2000 |
N-Linked oligosaccharides on the meprin A metalloprotease are important for secretion and enzymatic activity, but not for apical targeting.
Topics: Animals; Anti-Bacterial Agents; Asparagine; Bradykinin; Brefeldin A; Cell Line; Colchicine; DNA Mutational Analysis; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glutamine; Glycoside Hydrolases; Glycosylation; Hot Temperature; Humans; Immunoblotting; Indolizines; Metalloendopeptidases; Mice; Mutagenesis, Site-Directed; Oligosaccharides; Plasmids; Point Mutation; Protein Conformation; Protein Synthesis Inhibitors; Recombinant Proteins; Swainsonine; Time Factors; Transfection; Trypsin; Tunicamycin | 2000 |
Asparagine repeats are rare in mammalian proteins.
Topics: Animals; Asparagine; Databases, Factual; Dictyostelium; Drosophila; Glutamine; Humans; Recombination, Genetic; Trinucleotide Repeats; Yeasts | 2000 |
Specific glutamine and asparagine residues of gamma-S crystallin are resistant to in vivo deamidation.
Topics: Aged; Amino Acid Sequence; Asparagine; Cell Line; Chromatography, High Pressure Liquid; Crystallins; Glutamine; Humans; Middle Aged; Molecular Sequence Data; Molecular Weight; Peptide Mapping; Structure-Activity Relationship | 2000 |
Mutants provide evidence of the importance of glycosydic chains in the activation of lipase 1 from Candida rugosa.
Topics: Asparagine; Blotting, Western; Candida; Enzyme Activation; Glutamine; Glycosides; Glycosylation; Hydrogen-Ion Concentration; Lipase; Models, Molecular; Mutagenesis, Site-Directed; Pichia; Plasmids; Recombinant Proteins; Temperature; Water | 2000 |
Distribution of Q188R and N314D mutations in the Hungarian galactosemic population.
Topics: Amino Acid Substitution; Arginine; Asparagine; Aspartic Acid; Galactosemias; Gene Frequency; Genetic Carrier Screening; Genetics, Population; Glutamine; Humans; Hungary; Infant, Newborn; Neonatal Screening | 2000 |
Identification of essential amino acid residues in the Sinorhizobium meliloti glucosyltransferase ExoM.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Bacterial Proteins; Blotting, Western; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glucosyltransferases; Glutamine; Glycosyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Polysaccharides, Bacterial; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Sinorhizobium meliloti | 2000 |
Glutamine metabolism in endothelial cells: ornithine synthesis from glutamine via pyrroline-5-carboxylate synthase.
Topics: Alanine; Ammonia; Animals; Antimetabolites, Antineoplastic; Aorta; Asparagine; Aspartic Acid; Azaserine; Carbon Dioxide; Cattle; Cells, Cultured; Diazooxonorleucine; Endothelium, Vascular; Enzymes; Glutamic Acid; Glutamine; Humans; Microcirculation; Ornithine; Ornithine-Oxo-Acid Transaminase; Umbilical Veins; Venules | 2000 |
Interruption of the internal water chain of cytochrome f impairs photosynthetic function.
Topics: Animals; Asparagine; Brassica; Chlamydomonas reinhardtii; Crystallography, X-Ray; Cyanobacteria; Cytochromes; Cytochromes f; Glutamine; Hydrogen Bonding; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthesis; Plant Proteins; Protozoan Proteins; Sequence Homology, Amino Acid; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Water | 2000 |
Changes in the concentrations of amino acids in the cerebrospinal fluid that correlate with pain in patients with fibromyalgia: implications for nitric oxide pathways.
Topics: Adult; Aged; Analysis of Variance; Asparagine; Excitatory Amino Acids; Female; Fibromyalgia; Glutamine; Humans; Male; Middle Aged; N-Methylaspartate; Nitric Oxide; Pain; Pain Measurement; Signal Transduction | 2000 |
Two clusters of acidic amino acids near the NH2 terminus of complement component C4 alpha'-chain are important for C2 binding.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antibodies, Blocking; Asparagine; Aspartic Acid; Binding Sites, Antibody; Complement C2; Complement C4; COS Cells; Glutamic Acid; Glutamine; Humans; Molecular Mimicry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding | 2000 |
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cations; Crystallography, X-Ray; Cyclic AMP Response Element-Binding Protein; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrons; Escherichia coli; Glutamic Acid; Glutamine; Hydrogen Bonding; Ions; Kinetics; Leucine Zippers; Lysine; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Response Elements; Sequence Homology, Amino Acid; Signal Transduction; Somatostatin | 2000 |
Directed glycosylation of human coagulation factor X at residue 333. Insight into factor Va-dependent prothrombin catalysis.
Topics: Amino Acid Substitution; Asparagine; Catalysis; Factor IXa; Factor Va; Factor VIIa; Factor X; Factor Xa; Glutamine; Glycosylation; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Prothrombin; Recombinant Proteins; Substrate Specificity; Thromboplastin | 2000 |
Contribution of salt bridges near the surface of a protein to the conformational stability.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Glutamic Acid; Glutamine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Muramidase; Mutagenesis, Site-Directed; Potassium Chloride; Protein Conformation; Protein Denaturation; Salts; Surface Properties | 2000 |
Negative regulation of nitrate reductase gene expression by glutamine or asparagine accumulating in leaves of sulfur-deprived tobacco.
Topics: Asparagine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamine; Nicotiana; Nitrate Reductase; Nitrate Reductases; Plant Leaves; Plants, Toxic; Sulfur | 2000 |
A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Codon; Glutamine; Humans; Prions | 2000 |
Amino acid analysis. An overview.
Topics: Amino Acids; Asparagine; Cysteine; Cystine; Glutamine; Hydrolysis; Sensitivity and Specificity; Stereoisomerism; Tryptophan | 2000 |
Novel recombinant hemoglobin, rHb (beta N108Q), with low oxygen affinity, high cooperativity, and stability against autoxidation.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Carboxyhemoglobin; Glutamine; Hemoglobin A; Humans; Mass Spectrometry; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Protein Conformation; Recombinant Proteins | 2000 |
Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice.
Topics: Amino Acid Substitution; Animals; Asparagine; Cattle; Female; Genetic Engineering; Glutamine; Lactation; Lysine; Lysostaphin; Mammary Glands, Animal; Mastitis, Bovine; Mice; Mice, Transgenic; Milk; Recombinant Proteins; Staphylococcal Infections; Staphylococcus | 2001 |
Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
Topics: Amino Acid Substitution; Antimetabolites; Antiviral Agents; Asparagine; Bromodeoxyuridine; Cell Cycle; Ganciclovir; Glutamine; Herpesvirus 1, Human; Humans; Mutation; Nucleoside-Phosphate Kinase; Osteosarcoma; Thiouridine; Thymidine Kinase; Transfection; Tumor Cells, Cultured | 2001 |
N-linked carbohydrate on human leukocyte antigen-C and recognition by natural killer cell inhibitory receptors.
Topics: Amino Acid Substitution; Animals; Antigens, CD; Asparagine; Carbohydrate Conformation; Carbohydrate Metabolism; Carbohydrates; Cell Line, Transformed; COS Cells; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Glutamine; Glycosylation; HLA-C Antigens; Humans; Immunoglobulins; Killer Cells, Natural; Lectins, C-Type; Membrane Glycoproteins; Mice; NK Cell Lectin-Like Receptor Subfamily D; Protein Binding; Receptors, Immunologic; Receptors, KIR; Receptors, KIR2DL1; Receptors, Natural Killer Cell; Recombinant Fusion Proteins; Signal Transduction; Swainsonine; Transfection; Tumor Cells, Cultured | 2000 |
Structural analysis of the transcriptional activation region on Fis: crystal structures of six Fis mutants with different activation properties.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Dimerization; DNA; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Factor For Inversion Stimulation Protein; Gene Expression Regulation, Bacterial; Glutamine; Hydrogen Bonding; Integration Host Factors; Models, Molecular; Mutation; Nucleic Acid Conformation; Protein Denaturation; Protein Structure, Secondary; Thermodynamics; Transcriptional Activation | 2000 |
Lanthanide induced residual dipolar couplings for the conformational investigation of peripheral 15NH2 moieties.
Topics: Anisotropy; Asparagine; Binding Sites; Calbindins; Cerium; Dysprosium; Glutamine; Magnetics; Metalloproteins; Metals, Rare Earth; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; S100 Calcium Binding Protein G; Ytterbium | 2000 |
The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Genetic Complementation Test; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Kinetics; Mutagenesis, Site-Directed; Plasmodium falciparum; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2001 |
Ion chromatographic analysis of selected free amino acids and cations to investigate the change of nitrogen metabolism by herbicide stress in soybean (glycine max).
Topics: Alanine; Amino Acids; Arylsulfonates; Asparagine; Aspartic Acid; Cations; Chromatography, Ion Exchange; Glutamine; Glycine max; Herbicides; Nitrogen; Plant Structures; Potassium; Quaternary Ammonium Compounds; Sodium; Tissue Distribution | 2001 |
Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport.
Topics: Acetyltransferases; Amino Acid Sequence; Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Arylamine N-Acetyltransferase; Asparagine; beta-Alanine; Biological Transport; Brain; Carrier Proteins; Cell Cycle Proteins; Cloning, Molecular; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Mice; Molecular Sequence Data; Optic Nerve; Retina; Retinal Ganglion Cells; RNA, Messenger; Sequence Homology, Amino Acid; Sodium; Tissue Distribution; Transcription Factors | 2001 |
Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Topics: Acylation; Amino Acid Substitution; Asparagine; Aspartic Acid; beta-Lactamases; Binding Sites; Catalysis; Cephaloridine; Crystallization; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Glutamine; Hydrolysis; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Penicillin G; Staphylococcus aureus; Substrate Specificity | 2001 |
Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants.
Topics: Asparagine; Binding Sites; Calorimetry; Carbonic Anhydrases; Cations, Divalent; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Bonding; Ligands; Mutagenesis, Site-Directed; Protein Binding; Thermodynamics; Zinc | 2001 |
Stabilization of apoflavodoxin by replacing hydrogen-bonded charged Asp or Glu residues by the neutral isosteric Asn or Gln.
Topics: Amino Acid Substitution; Anabaena; Apoproteins; Asparagine; Aspartic Acid; Bacterial Proteins; Base Sequence; Circular Dichroism; Cyanobacteria; Flavodoxin; Glutamic Acid; Glutamine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Urea | 2001 |
Purification and characterization of N-glycosylation mutant mouse and human P-glycoproteins expressed in Pichia pastoris cells.
Topics: Adenosine Triphosphatases; Alanine; Animals; Asparagine; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Binding Sites; Catalysis; Chromatography, Agarose; Dithiothreitol; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycosylation; Humans; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Mice; Mutagenesis, Site-Directed; Mutation; Photoaffinity Labels; Pichia; Plasmids; Protein Binding; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Vasodilator Agents; Verapamil | 2001 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
Control of metalloprotein reduction potential: the role of electrostatic and solvation effects probed on plastocyanin mutants.
Topics: Asparagine; Electrochemistry; Glutamine; Hydrogen Bonding; Leucine; Metalloproteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Plastocyanin; Quantitative Structure-Activity Relationship; Solvents; Spinacia oleracea; Static Electricity; Surface Properties; Thermodynamics | 2001 |
Deamidation of Asn-143 of gamma S crystallin from protein aggregates of the human lens.
Topics: Aging; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Deamination; Glutamine; Humans; Lens, Crystalline; Middle Aged; Molecular Weight | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 3. A steady-state kinetic model consistent with the behavior of both wild-type and variant enzymes at all relevant pH values.
Topics: Acetaldehyde; Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Catalytic Domain; Computer Simulation; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Pyruvates; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 2001 |
A dual-specific Glu-tRNA(Gln) and Asp-tRNA(Asn) amidotransferase is involved in decoding glutamine and asparagine codons in Acidithiobacillus ferrooxidans.
Topics: Asparagine; Aspartate-tRNA Ligase; Cloning, Molecular; Codon; Enzyme Activation; Escherichia coli; Gammaproteobacteria; Glutamine; Nitrogenous Group Transferases; Protein Biosynthesis; Pseudomonas putida; RNA, Transfer, Amino Acyl; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Substrate Specificity | 2001 |
Asparagine uptake in rat hepatocytes: resolution of a paradox and insights into substrate-dependent transporter regulation.
Topics: Amino Acids; Androstadienes; Animals; Asparagine; Binding, Competitive; Biological Transport; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Glutamine; Hepatocytes; Kinetics; Lithium; Male; Models, Biological; Morpholines; Ornithine Decarboxylase; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Substrate Specificity; Time Factors; Wortmannin | 2001 |
A method for assessing the side chain orientations of histidine, asparagine, and glutamine as well as the protonation forms of histidine in protein structures.
Topics: Aldehyde Reductase; Asparagine; beta-Lactamases; Glutamine; Histidine; Hydrogen Bonding; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Trypsin | 2001 |
A program of Yersinia enterocolitica type III secretion reactions is activated by specific signals.
Topics: Albumins; Asparagine; Aspartic Acid; Bacterial Outer Membrane Proteins; Calcium; Genes, Regulator; Glutamic Acid; Glutamine; HeLa Cells; Humans; Mutation; Signal Transduction; Yersinia enterocolitica | 2001 |
Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion.
Topics: Amino Acid Sequence; Asparagine; Ataxin-3; Fungal Proteins; Gene Expression; Genes, Fungal; Glutamine; Humans; Machado-Joseph Disease; Microscopy, Fluorescence; Molecular Chaperones; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; Peptide Termination Factors; Peptides; Phenotype; Prions; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2001 |
Accurate orientation of the functional groups of asparagine and glutamine side chains using one- and two-bond dipolar couplings.
Topics: Asparagine; DNA-Binding Proteins; Glutamine; Membrane Proteins; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Protein Conformation; Stereoisomerism | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Deamidation of human proteins.
Topics: Asparagine; Glutamine; Humans; Protein Conformation; Proteins | 2001 |
Simultaneous replacement of Asp-L210 and Asp-M17 with Asn increases proton uptake by Glu-L212 upon first electron transfer to QB in reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport; Glutamic Acid; Glutamine; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Protons; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared | 2001 |
Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Asparagine; Aspartic Acid; Binding Sites; Complement C1; Complement C1q; Complement Pathway, Classical; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Rats | 2001 |
Two simple NMR experiments for measuring dipolar couplings in asparagine and glutamine side chains.
Topics: Anisotropy; Asparagine; Bacterial Proteins; Glutamine; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Protein Conformation; Troponin C | 2001 |
The mouse guanylate kinase double mutant E72Q/D103N is a functional adenylate kinase.
Topics: Adenosine Monophosphate; Adenylate Kinase; Animals; Asparagine; Binding Sites; DNA, Complementary; Escherichia coli; Genetic Complementation Test; Genetic Vectors; Glutamine; Guanosine Monophosphate; Guanylate Kinases; Mice; Models, Chemical; Mutagenesis; Mutation; Nucleoside-Phosphate Kinase; Spectrophotometry; Substrate Specificity; Time Factors | 2001 |
Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed).
Topics: Animals; Asparagine; Cnidaria; Genetic Techniques; Glutamine; Kinetics; Luminescent Proteins; Microscopy, Fluorescence; Mutagenesis; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Saccharomyces cerevisiae; Temperature; Time Factors | 2002 |
Characterization of polyanionic collagen prepared by selective hydrolysis of asparagine and glutamine carboxyamide side chains.
Topics: Amides; Animals; Asparagine; Biocompatible Materials; Cattle; Collagen; Collagen Type I; Drug Stability; Elastin; Glutamine; Hydrolysis; Ions; Microscopy, Electron; Protein Conformation | 2001 |
Amino acid runs in eukaryotic proteomes and disease associations.
Topics: Animals; Arabidopsis; Asparagine; Caenorhabditis elegans; Drosophila melanogaster; Genome; Genome, Human; Glutamine; Humans; Leucine; Saccharomyces cerevisiae; Serine; Species Specificity; Transcription, Genetic | 2002 |
Amyloid fibers are water-filled nanotubes.
Topics: Alzheimer Disease; Amyloid; Asparagine; Crystallography, X-Ray; Exons; Fourier Analysis; Fungal Proteins; Glutamine; Humans; Huntingtin Protein; Hydrogen Bonding; Microscopy, Electron; Nerve Tissue Proteins; Nuclear Proteins; Peptide Termination Factors; Peptides; Prions; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins | 2002 |
Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Animals; Asparagine; Circular Dichroism; Exons; Fungal Proteins; Glutamine; Hemoglobins; Humans; Hydrogen-Ion Concentration; Light; Lysine; Mice; Mice, Transgenic; Molecular Sequence Data; Peptide Fragments; Peptide Termination Factors; Peptides; Prions; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Scattering, Radiation; Thermodynamics; Ultraviolet Rays; X-Ray Diffraction | 2002 |
Effects of amino acid substitutions at beta 131 on the structure and properties of hemoglobin: evidence for communication between alpha 1 beta 1- and alpha 1 beta 2-subunit interfaces.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cysteine; Globins; Glutamine; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Mercuribenzoates; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 2002 |
Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality.
Topics: Amino Acids; Animals; Antibodies; Apoptosis; Asparagine; Betaine; Carbon Dioxide; Cell Size; CHO Cells; Cricetinae; Glucose; Glutamine; Glycine; Hybridomas; Hydrogen-Ion Concentration; Ion Transport; Osmolar Concentration; Sensitivity and Specificity; Threonine; Tissue Plasminogen Activator | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Glutamine; Histidine Ammonia-Lyase; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Petroselinum; Phenylalanine Ammonia-Lyase; Sequence Homology; Substrate Specificity; Tyrosine | 2002 |
Short-term changes in xylem N compounds in Lolium perenne following defoliation.
Topics: Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Hydroponics; Logistic Models; Lolium; Nitrates; Nitrogen; Nitrogen Radioisotopes; Plant Leaves; Time Factors | 2002 |
X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
Topics: Amino Acid Sequence; Arginine; Asparagine; Binding Sites; Dose-Response Relationship, Drug; Glutamine; Histidine; Humans; Isoenzymes; K562 Cells; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonucleases; Sequence Homology, Amino Acid; Streptomyces aureofaciens; Temperature; Tumor Cells, Cultured; X-Ray Diffraction | 2002 |
The N-linked oligosaccharides at the amino terminus of human apoB are important for the assembly and secretion of VLDL.
Topics: Amino Acid Substitution; Apolipoproteins B; Asparagine; Glutamine; Humans; Lipoproteins, VLDL; Oligosaccharides; Structure-Activity Relationship; Tunicamycin | 2002 |
Can the nitrogenous composition of xylem sap be used to assess salinity stress in Casuarina glauca?
Topics: Arginine; Asparagine; Citrulline; Glutamine; Hamamelidaceae; Nitrogen Compounds; Plant Stems; Proline; Queensland; Rain; Soil; Trees; Water | 2002 |
Acrylamide from Maillard reaction products.
Topics: Acrylamide; Amino Acids; Asparagine; Food; Glucose; Glutamine; Glycosides; Hot Temperature; Maillard Reaction; Methionine | 2002 |
The relative rates of glutamine and asparagine deamidation in glucagon fragment 22-29 under acidic conditions.
Topics: Acids; Asparagine; Deamination; Glucagon; Glutamine; Hydrogen-Ion Concentration; Peptide Fragments | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73.
Topics: Animals; Asparagine; Cathepsin B; Cathepsin L; Cathepsins; Chickens; Crystallography, X-Ray; Cystatins; Cysteine Endopeptidases; Glutamine; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence | 2002 |
Excitatory amino acid release in the spinal cord caused by plantar incision in the rat.
Topics: Animals; Asparagine; Aspartic Acid; Dermatologic Surgical Procedures; Glutamic Acid; Glutamine; Glycine; Male; Microdialysis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord | 2002 |
The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism.
Topics: Anions; Asparagine; Binding Sites; Catalysis; Cations, Divalent; Cell Membrane; Cobalt; Crystallization; Crystallography, X-Ray; Glutamine; Group II Phospholipases A2; Histidine; Humans; Hydrolysis; Micrococcus luteus; Mutagenesis, Site-Directed; Nickel; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Recombinant Proteins; Substrate Specificity | 2002 |
Characterization of nitrogen relationships between Sorghum bicolor and the root-hemiparasitic angiosperm Striga hermonthica (Del.) Benth. using K15 NO3 as isotopic tracer.
Topics: Algorithms; Asparagine; Biological Transport; Glutamine; Nitrates; Nitrogen; Nitrogen Isotopes; Plant Roots; Poaceae; Potassium Compounds; Striga | 2003 |
Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Glutamine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; Protons; Recombinant Proteins; Rhodospirillum rubrum | 2003 |
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Crystallography, X-Ray; DNA; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Humans; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Substrate Specificity | 2003 |
Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivity.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Calcium; Catalytic Domain; Cattle; Glutamic Acid; Glutamine; Metals, Alkaline Earth; Mutagenesis, Site-Directed; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Stereoisomerism; Streptomyces antibioticus; Substrate Specificity; Type C Phospholipases | 2003 |
Effect of aspartate and asparagine supplementation on fatigue determinants in intense exercise.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Blood Glucose; Dietary Supplements; Glutamine; Glycogen; Lactic Acid; Liver Glycogen; Male; Muscle Fatigue; Muscle, Skeletal; Physical Conditioning, Animal; Physical Exertion; Random Allocation; Rats; Rats, Wistar; Swimming | 2003 |
Redox potential of quinones in photosynthetic reaction centers from Rhodobacter sphaeroides: dependence on protonation of Glu-L212 and Asp-L213.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport; Glutamic Acid; Glutamine; Light; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Protons; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared | 2003 |
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
Topics: Amino Acids; Arabidopsis; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Gene Expression Regulation, Plant; Germination; Glutamic Acid; Glutamine; Hydro-Lyases; Lysine; Methionine; Mutation; Plants, Genetically Modified; Pterocarpans; Seeds; Signal Transduction; Threonine | 2003 |
Revisiting the steady state kinetic mechanism of glutamine-dependent asparagine synthetase from Escherichia coli.
Topics: Ammonia; Asparagine; Aspartate-Ammonia Ligase; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Catalytic Domain; Escherichia coli; Glutamine; Kinetics; Models, Biological; Models, Molecular; Protein Conformation | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
Characterization of Nkx3.2 DNA binding specificity and its requirement for somitic chondrogenesis.
Topics: 3T3 Cells; Amino Acid Motifs; Animals; Asparagine; Base Sequence; Binding Sites; Chick Embryo; Chondrocytes; Cloning, Molecular; DNA; Genes, Reporter; Glutamine; Glutathione Transferase; Homeodomain Proteins; Mice; Molecular Sequence Data; Mutation, Missense; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Transcription Factors; Transcription, Genetic | 2003 |
Biomimetic mineralization of charged collagen matrices: in vitro and in vivo study.
Topics: Animals; Anions; Asparagine; Biocompatible Materials; Bone and Bones; Calcium Phosphates; Cattle; Collagen; Fracture Healing; Glutamine; In Vitro Techniques; Male; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Surface Properties; Tibia; X-Ray Diffraction | 2003 |
Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers.
Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Asparagine; Bupivacaine; Cells, Cultured; Glutamic Acid; Glutamine; Humans; Mutagenesis, Site-Directed; Point Mutation; Rats; Sodium Channel Blockers; Sodium Channels; Stereoisomerism | 2003 |
Two-electrode voltage-clamp analysis of Na,K-ATPase asparagine 776 mutants.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Female; Glutamine; Kinetics; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Xenopus | 2003 |
Carotenoprotein complexes in entomostracan crustaceans (Streptocephalus dichotomus and Moina micrura).
Topics: Animals; Anostraca; Asparagine; beta Carotene; Canthaxanthin; Carotenoids; Chromatography, Thin Layer; Cladocera; Fresh Water; Glutamine; Glycine; Lutein; Molecular Structure; Proteins; Xanthophylls | 2003 |
A method to assess compositional bias in biological sequences and its application to prion-like glutamine/asparagine-rich domains in eukaryotic proteomes.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Caenorhabditis elegans Proteins; Computational Biology; Drosophila Proteins; Eukaryotic Cells; Fungal Proteins; Glutamine; Humans; Molecular Sequence Data; Prions; Protein Structure, Tertiary; Proteome; Saccharomycetales; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Selection, Genetic; Sequence Analysis, Protein | 2003 |
Sequence context strongly modulates association of polar residues in transmembrane helices.
Topics: Amino Acid Sequence; Amino Acids, Acidic; Amino Acids, Basic; Asparagine; Aspartic Acid; Capsid; Capsid Proteins; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins | 2003 |
Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104.
Topics: Asparagine; Cytosol; Fungal Proteins; Glutamine; Heat-Shock Proteins; Magnetic Resonance Spectroscopy; Models, Biological; Peptide Biosynthesis; Peptide Termination Factors; Peptides; Prions; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Tyrosine | 2003 |
Potential of acrylamide formation, sugars, and free asparagine in potatoes: a comparison of cultivars and farming systems.
Topics: Acrylamides; Agriculture; Amino Acids; Asparagine; Carbohydrates; Fructose; Glucose; Glutamine; Hot Temperature; Sensitivity and Specificity; Solanum tuberosum; Sucrose | 2003 |
Effect of additional N-glycosylation signal in the N-terminal region on intracellular function of the human gonadotropin alpha-subunit.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; CHO Cells; Chorionic Gonadotropin, beta Subunit, Human; Cricetinae; Cricetulus; Dimerization; Electrophoretic Mobility Shift Assay; Glutamine; Glycoprotein Hormones, alpha Subunit; Glycosylation; Humans; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mutation; Terminal Repeat Sequences; Threonine | 2003 |
Specific isotopic labeling and photooxidation-linked structural changes in the manganese-stabilizing subunit of photosystem II.
Topics: Asparagine; Aspartic Acid; Escherichia coli; Gas Chromatography-Mass Spectrometry; Gene Expression; Glutamic Acid; Glutamine; Isotope Labeling; Manganese; Oxidation-Reduction; Photochemistry; Photosynthesis; Photosystem II Protein Complex; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Water | 2003 |
Evolution of amino acid metabolism inferred through cladistic analysis.
Topics: Amino Acids; Asparagine; Aspartic Acid; Biochemical Phenomena; Biochemistry; Biological Evolution; Citric Acid Cycle; Enzymes; Glutamic Acid; Glutamine; Models, Biological; Multigene Family; Phylogeny; Software; Statistics as Topic; Substrate Specificity | 2003 |
Transamination and associated deamidation of asparagine and glutamine.
Topics: Asparagine; Glutamine; Keto Acids; Ketones | 1952 |
Preparation of enzymatic reactions of the keto analogues of asparagine and glutamine.
Topics: Asparagine; Glutamine; Keto Acids; Ketones; Organic Chemicals | 1953 |
[Synthesis of protein from asparagine and glutamine in wheat sprouts].
Topics: Asparagine; Biochemical Phenomena; Dietary Fats, Unsaturated; Glutamine; Plant Oils; Proteins; Triticum | 1953 |
[Variation of structure and of chemical properties of asparagine and glutamine].
Topics: Asparagine; Glutamine | 1953 |
Nature and extent of the biochemical lesion in human epileptogenic cerebral cortex; an approach to its control in vitro and in vivo.
Topics: Asparagine; Cerebral Cortex; Epilepsy; Glutamine; Humans; In Vitro Techniques | 1955 |
Presence of glutamine and asparagine in enzymatic hydrolysates of oxytocin and vasopressin.
Topics: Arginine Vasopressin; Asparagine; Endopeptidases; Glutamine; Humans; Hydrolases; Oxytocin; Peptide Hydrolases; Vasopressins | 1954 |
[Metabolism of asparagine, glutamine, and glutathione].
Topics: Asparagine; Glutamine; Glutathione | 1954 |
Diminished phenylketonuria in phenylpyruvic oligophrenia after administration of L-glutamine, L-glutamate or L-asparagine.
Topics: Asparagine; Body Fluids; Glutamic Acid; Glutamine; Humans; Intellectual Disability; Ketones; Phenylketonurias; Urine | 1956 |
Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine.
Topics: Animals; Asparagine; Biochemical Phenomena; Carcinoma 256, Walker; Glutamine; Humans; In Vitro Techniques; Neoplasms | 1956 |
Anticonvulsant properties of l-glutamine and l-asparagine in mice and rats.
Topics: Animals; Anticonvulsants; Asparagine; Glutamine; Mice; Rats | 1957 |
Evidence that glutamine is a precursor of asparagine in a human cell in tissue culture.
Topics: Asparagine; Biochemical Phenomena; Glutamine; Immunologic Tests; Research Design | 1957 |
Enzymatic transfer and hydrolysis involving glutamine and asparagine.
Topics: Asparagine; Glutamine; Hydrolysis; Mycobacterium | 1957 |
Amino acid composition of alpha-chymotrypsinogen, including estimation of asparagine and glutamine.
Topics: Amino Acids; Asparagine; Chymotrypsinogen; Enzyme Precursors; Glutamine | 1957 |
On the efficacy of asparagine, glutamine, gamma-aminobutyric acid and 1-pyrroiidinone in preventing chemically induced seizures in mice.
Topics: Amino Acids; Animals; Asparagine; Central Nervous System Stimulants; gamma-Aminobutyric Acid; Glutamine; Mice; Pyrrolidinones; Seizures | 1957 |
Studies on the amide and C-terminal residues in proteins. 5. Estimation of asparagine and glutamine residues.
Topics: Amides; Asparagine; Glutamine; Proteins | 1958 |
The use of asparagine and glutamine for the biosynthesis of casein and plasma proteins.
Topics: Asparagine; Blood Proteins; Caseins; Glutamine | 1958 |
[The action of glutamine and asparagine on the in vitro metabolism of acetylcholine in the cerebral cortex from dogs predisposed to epilepsy induced by afferent excitation].
Topics: Acetylcholine; Animals; Asparagine; Cerebral Cortex; Dogs; Epilepsy; Glutamine; In Vitro Techniques; Synaptic Transmission | 1958 |
The biosynthesis of dicarboxylic amino acids and enzymic transformations of amides in plants.
Topics: Amides; Amino Acids, Dicarboxylic; Anesthetics, Local; Asparagine; Aspartic Acid; Biochemical Phenomena; Glutamates; Glutamine; Plants | 1958 |
Enthalpies of hydrolysis of glutamine and asparagine and of ionization of glutamic and aspartic acids.
Topics: Asparagine; Aspartic Acid; Glutamates; Glutamine; Hydrolysis; Thermodynamics | 1959 |
[Determination of asparagine and glutamine residues in Taka-amylase A].
Topics: alpha-Amylases; Amylases; Asparagine; Glutamine; Humans | 1960 |
Metabolic studies of rickettsiae. V. Metabolism of glutamine and asparagine in Rickettsia mooseri.
Topics: Asparagine; Glutamine; Humans; Rickettsia; Rickettsia typhi | 1960 |
Glucosylglycine, asparagine, and glutamine metabolism in Escherichia coli.
Topics: Asparagine; Escherichia coli; Glutamine; Glycine | 1960 |
[Experimental research on the anticonvulsant properties of 1-glutamine, 1-asparagine, gamma-aminobutyric acid and gamma-amino-beta-hydroxybutyric acid].
Topics: Amino Acids; Anticonvulsants; Antifibrinolytic Agents; Asparagine; Epilepsy; gamma-Aminobutyric Acid; Glutamine | 1962 |
Growth of Listeria monocytogenes in defined media.
Topics: Alanine; Arginine; Asparagine; Culture Media; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Listeria monocytogenes; Methionine; Proteins; Valine | 1961 |
Heat capacities from 11 to 305 degree K, entropies and free energies of formation of L-asparagine monohydrate, L-aspartic acid, L-glutamic acid, and L-glutamine.
Topics: Asparagine; Aspartic Acid; Entropy; Glutamates; Glutamic Acid; Glutamine; Hot Temperature | 1963 |
Determination of protein-bound glutamine and asparagine.
Topics: Asparagine; Glutamine; Proteins | 1962 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
AN ENZYMIC MICROMETHOD FOR DETERMINATION OF GLUTAMINE AND ASPARAGINE IN BLOOD.
Topics: Amidohydrolases; Animals; Asparagine; Blood Chemical Analysis; Colorimetry; Glutaminase; Glutamine; Guinea Pigs; Microchemistry; Pseudomonas; Rabbits; Rats; Research | 1963 |
PAPER CHROMATOGRAPHY USING LIQUID ION EXCHANGERS.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chromatography; Chromatography, Paper; Glutamates; Glutamine; Ion Exchange Resins; Research | 1963 |
CARBON DIOXIDE FIXATION IN THE JA-1 SARCOMA IN VITRO.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fumarates; Glutamates; Glutamine; In Vitro Techniques; Isoleucine; Leucine; Metabolism; Propionates; Proteins; Pyruvates; Sarcoma; Sarcoma, Experimental; Succinates | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
ASPARAGINE-C14 AND GLUTAMINE-C14 FROM ANIMAL CELL PROTEIN AND THEIR CHEMICAL DEGRADATION.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Glutamine; Ion Exchange Resins; Malates; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Research; Sarcoma; Sarcoma, Experimental | 1963 |
[RECENT KNOWLEDGE ABOUT THE PROBLEM OF PHENYLPYRUVIC OLIGOPHRENIA. FREQUENCY, GENETICS, BIOCHEMISTRY, DIAGNOSIS, AND THERAPEUTICS].
Topics: Asparagine; Biochemistry; Diet; Diet Therapy; Genetics, Medical; Glutamine; Humans; Knowledge; Nialamide; Pathology; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Prognosis; Urine | 1963 |
THE BIOSYNTHESIS OF ASPARAGINE IN THE ETIOLATED SOYBEAN SEEDLING. I. RELATIONSHIP OF ASPARAGINE FORMATION TO CHANGES OF NITROGEN COMPOUNDS.
Topics: Acetates; Asparagine; Darkness; Glutamates; Glutamine; Glycine max; Ketoglutaric Acids; Nitrogen; Nitrogen Compounds; Plant Proteins; Proteins; Research; Seedlings | 1963 |
THE METABOLISM OF THE ORGANIC ACIDS OF TOBACCO LEAVES. XX. EFFECT OF CULTURE OF EXCISED LEAVES IN SOLUTIONS OF POTASSIUM ASPARTATE AND OF ASPARAGINE.
Topics: Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Citrates; Culture Media; Glutamine; Ion Exchange Resins; Malates; Metabolism; Nicotiana; Pharmacology; Proteins; Research; Succinates | 1963 |
ENZYMATIC SYNTHESIS OF GAMMA-GLUTAMYLHYDROXAMIC ACID FROM GLUTAMIC ACID AND HYDROXYLAMINE.
Topics: Amidohydrolases; Ammonia; Antimetabolites; Asparagine; Azaserine; Azotobacter; Carbon Isotopes; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Pharmacology; Proteins; Research; Streptomycin | 1963 |
[THE EXCRETION OF AMMONIA BY A FRESH WATER TELEOST: CYPRINUS CARPIO L].
Topics: Ammonia; Animals; Asparagine; Blood Chemical Analysis; Carps; Cell Respiration; Fishes; Fresh Water; Glutamine; Hydroxylamines; Liver; Metabolism; Nitrogen; Periodicity; Research; Respiration | 1963 |
[RESEARCH ON THE ROLE OF THE CECAL WALL OF THE RABBIT IN THE METABOLISM OF AMINO ACIDS].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Blood Chemical Analysis; Cecum; Chromatography; Glutamates; Glutamine; Perfusion; Physiology; Proteins; Rabbits; Research | 1963 |
THE DETECTION OF AMIDES ON PAPER CHROMATOGRAMS.
Topics: Amides; Asparagine; Chromatography; Chromatography, Paper; Citrulline; Cyanides; Glutamine; Niacin; Niacinamide; Research; Urea; Uric Acid | 1964 |
THE METABOLISM OF THE VOLATILE AMINES: VII. THE CLINICAL SIGNIFICANCE OF TWO COMPONENTS OF THE BLOOD AMMONIA LEVEL.
Topics: Amines; Ammonia; Arginine; Asparagine; Blood Chemical Analysis; Glutamates; Glutamine; Hematologic Tests; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Potassium; Proteins | 1964 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
[THE EFFECT OF ALKALI ON COLLAGEN. THE CHANGE IN THE CHARGE PATTERN OF THE TROPOCOLLAGEN MOLECULE AND SPLITTING OF INTRA- AND INTERMOLECULAR COMPOUNDS].
Topics: Alkalies; Asparagine; Chemistry Techniques, Analytical; Collagen; Glutamine; Research; Tropocollagen | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
[CONCERNING LINKED PRODUCTS OF GLUTAMIC ACID, GLUTAMINE, ASPARAGINE AND AROMATIC CARBOXYLIC ACIDS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Asparagine; Benzoates; Chromatography; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Hippurates; Kidney; Liver; Metabolism; Phenylacetates; Rats; Research; Ultraviolet Rays | 1964 |
MICROBIOLOGICAL ASSAY FOR L-ASPARAGINE WITH A STREPTOCOCCUS BOVIS MUTANT.
Topics: Asparagine; Culture Media; Dipeptides; Glutamine; Mutation; Pharmacology; Research; Spectrophotometry; Streptococcus; Streptococcus bovis | 1964 |
[DETERMINATION OF AMMONIA IN DEPROTEINIZED BLOOD].
Topics: Amino Acids; Ammonia; Asparagine; Biomedical Research; Blood Chemical Analysis; Blood Proteins; Glutamine; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Trichloroacetic Acid | 1964 |
THE EFFECT OF NITROGENOUS SUBSTANCES ON THE TIME OF FLOCCULATION OF SACCHAROMYCES CEREVISIAE.
Topics: Aminobutyrates; Ammonia; Asparagine; Benzoates; Colloids; Culture Media; Flocculation; Glucosamine; Glucose; Glutamine; Growth; Microbiology; Nitrogen; Pantothenic Acid; Proteins; Research; Saccharomyces; Saccharomyces cerevisiae; Yeasts | 1964 |
[EFFECT OF ORAL AMINO ACIDS ON THE AMMONIA CONCENTRATION IN THE PORTAL BLOOD].
Topics: Alanine; Amino Acids; Ammonia; Animals; Asparagine; Blood; Cystine; Dogs; Glutamates; Glutamine; Glycine; Methionine; Pharmacology; Portal Vein; Research | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
EFFECT OF ORALLY ADMINISTERED AMINO ACIDS ON PORTAL BLOOD AMMONIA CONCENTRATIONS.
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Blood; Cystine; Dogs; Glutamates; Glutamine; Glycine; Methionine; Pharmacology; Portal System; Research | 1964 |
[ON THE SYNTHESIS OF GLYCINE BY THE CHICK EMBRYONIC LIVER].
Topics: Amino Acids; Animals; Asparagine; Chick Embryo; Glutamine; Glycine; Liver; Research | 1964 |
[INCLUSION OF N15 INTO FREE AMINO ACIDS AND GLUTAMINE DURING ASSIMILATION OF N15-AMMONIA BY THE FUNGUS CANDIDA TROPICALIS].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Candida; Candida tropicalis; Glutamates; Glutamine; Nitrogen; Research | 1964 |
AMINO ACID UTILIZATION BY ALCALIGENES VISCOLACTIS FOR GROWTH AND SLIME PRODUCTION.
Topics: Alcaligenes; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Colorimetry; Culture Media; Glucose; Glutamic Acid; Glutamine; Lactose; Nitrogen; Proline; Research; Salts; Tyrosine | 1965 |
A SYNTHETIC MEDIUM FOR EXTREMELY HALOPHILIC BACTERIA.
Topics: Adenine Nucleotides; Amino Acids; Ammonium Chloride; Asparagine; Betaine; Culture Media; Glutamine; Glycerol; Halobacterium; Metabolism; Pharmacology; Research; Sarcina; Uracil Nucleotides; Vitamins | 1965 |
THE METABOLISM OF THE DIGESTIVE GLANDS OF TWO SPECIES OF MARINE GASTROPOD (MELANERITA MELANOTRAGUS AND AUSTROCOCHLEA OBTUSA).
Topics: Acetates; Alanine; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Autoradiography; Carbohydrate Metabolism; Carbon Dioxide; Chromatography; Citrates; Citric Acid Cycle; Fumarates; Gastrointestinal Tract; Gastropoda; Glucose; Glutamates; Glutamine; Glycolysis; Malates; Mollusca; Research; Succinates | 1965 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
REGULATION OF CEREBRAL METABOLISM OF AMINO ACIDS. IV. INFLUENCE OF AMINO ACID LEVELS ON LEUCINE UPTAKE, UTILIZATION AND INCORPORATION INTO PROTEIN IN VIVO.
Topics: Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Blood Volume; Brain Chemistry; Cerebral Cortex; Diet; Extracellular Space; Glutamates; Glutamine; Inulin; Leucine; Nerve Tissue Proteins; Proteins; Rats; Research; Serum Albumin; Serum Albumin, Radio-Iodinated | 1965 |
UPTAKE OF FREE PLASMA AMINO ACIDS BY THE LACTATING COW'S UDDER AND AMINO ACID COMPOSITION OF UDDER LYMPH.
Topics: Amino Acids; Animals; Arteries; Asparagine; Biochemical Phenomena; Biochemistry; Blood; Cattle; Chromatography; Citrulline; Female; Glutamine; Humans; Lactation; Lymph; Mammary Glands, Animal; Manometry; Milk; Milk Proteins; Plasma; Proline; Research; Veins | 1965 |
Nutrition of Leptospira pomona. 1. A chemically defined substitute for rabbit serum ultrafiltrate.
Topics: Animals; Asparagine; Culture Media; Glutamine; Leptospira; Rabbits; Renal Dialysis; Thiamine | 1962 |
Identification of Pseudomonas proteins coordinately induced by acidic amino acids and their amides: a two-dimensional electrophoresis study.
Topics: Asparaginase; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Glutaminase; Glutamine; Periplasm; Proteomics; Pseudomonas fluorescens; Pseudomonas putida; Reverse Transcriptase Polymerase Chain Reaction; Sigma Factor | 2003 |
Amyloid nucleation and hierarchical assembly of Ure2p fibrils. Role of asparagine/glutamine repeat and nonrepeat regions of the prion domains.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amyloid; Asparagine; Benzothiazoles; Dimerization; Glutamine; Glutathione Peroxidase; Hydrogen-Ion Concentration; Kinetics; Microscopy, Atomic Force; Molecular Sequence Data; Mutation; Prions; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Thiazoles; Time Factors | 2004 |
Nitrogen starvation-induced changes in amino acid and free ammonium pools in Schizophyllum commune colonies.
Topics: Alanine; Amino Acids; Ammonium Sulfate; Asparagine; Culture Media; Glutamine; Mycelium; Nitrogen; Schizophyllum | 2003 |
Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.
Topics: Alanine; Allosteric Site; Asparagine; Aspartic Acid; Binding Sites; Cations; Dose-Response Relationship, Drug; Glutamine; Humans; Hydrolysis; Ions; Kinetics; Lithium; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Rubidium; Serine; Sodium; Substrate Specificity; Thrombin; Trypsin | 2004 |
The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Biological Transport; Biotinylation; Cell Line; Cell Membrane; COS Cells; Glutamic Acid; Glutamine; Humans; Iodides; Kinetics; Mutation, Missense; Sodium; Symporters; Thyroid Gland | 2004 |
Role of glycosylation in the organic anion transporter OAT1.
Topics: Animals; Anions; Asparagine; Binding Sites; Biological Transport; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cloning, Molecular; COS Cells; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycosylation; HeLa Cells; Humans; Immunoblotting; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mutagenesis, Site-Directed; Mutation; Organic Anion Transport Protein 1; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Transfection | 2004 |
Mutant R1 proteins from Escherichia coli class Ia ribonucleotide reductase with altered responses to dATP inhibition.
Topics: Adenosine Triphosphate; Allosteric Site; Asparagine; Binding Sites; Cell Division; Dose-Response Relationship, Drug; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Kinetics; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Protein Binding; Ribonucleotide Reductases; Substrate Specificity; Surface Plasmon Resonance | 2004 |
The enzymatic formation of hydroxamic acids from glutamine and asparagine.
Topics: Asparagine; Glutamine; Hydroxamic Acids | 1950 |
The effect of hydroxylamine on the metabolism of glutamine and asparagine.
Topics: Asparagine; Glutamine; Hydroxylamine; Hydroxylamines | 1951 |
[Biologic synthesis of asparagine and glutamine by means of re-amidization].
Topics: Asparagine; Biological Products; Glutamine | 1951 |
Utilization of glutamine and asparagine and their peptides by micro-organisms.
Topics: Asparagine; Glutamine; Lactobacillus; Peptides | 1952 |
The synthesis of glutamine and asparagine peptides and of glutamine.
Topics: Asparagine; Glutamine; Peptides | 1952 |
The utilization of glutamine and asparagine peptides by microorganisms.
Topics: Asparagine; Bacteria; Glutamine; Peptides | 1952 |
Properties and physiological role of asparagine and glutamine, with a new interpretation of the structure of asparagine.
Topics: Asparagine; Glutamine | 1952 |
Certain aspects of intermediary metabolism of glutamine, asparagine, and glutathione.
Topics: Amino Acids; Asparagine; Biochemical Phenomena; Enzymes; Glutamine; Glutathione | 1952 |
Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide.
Topics: Amides; Asparagine; beta-Crystallin B Chain; Chromatography, Gel; Circular Dichroism; Crystallins; Electrophoresis, Polyacrylamide Gel; Glutamine; Hot Temperature; Humans; Lasers; Mass Spectrometry; Middle Aged; Molecular Weight; Mutagenesis, Site-Directed; Nephelometry and Turbidimetry; Point Mutation; Protein Conformation; Protein Denaturation; Protein Structure, Quaternary; Protein Subunits; Recombinant Proteins; Scattering, Radiation | 2004 |
Protein splicing of a Pyrococcus abyssi intein with a C-terminal glutamine.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacterial Proteins; Base Sequence; DNA Polymerase II; DNA Primers; Glutamine; Hydrogen-Ion Concentration; Kinetics; Protein Splicing; Protein Subunits; Pyrococcus abyssi; Recombinant Fusion Proteins; Thermodynamics | 2004 |
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Carbon-Oxygen Lyases; Crystallography, X-Ray; Deuterium Exchange Measurement; Deuterium Oxide; Dihydroxyacetone Phosphate; Enzyme Inhibitors; Escherichia coli Proteins; Glutamine; Glycolates; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Insertional; Protein Conformation; Recombinant Proteins; Substrate Specificity; Thermodynamics | 2004 |
A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
Topics: Amino Acid Substitution; Asparagine; Bacteriophage M13; Base Pair Mismatch; Binding Sites; Deoxyribonucleotides; DNA Primers; Gene Frequency; Glutamine; HIV Reverse Transcriptase; HIV-1; Isoleucine; Kinetics; Lac Operon; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Substrate Specificity; Templates, Genetic; Valine | 2004 |
Short sequences of non-proline residues can adopt the polyproline II helical conformation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Circular Dichroism; Glutamine; Oligopeptides; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Spectrophotometry; Valine | 2004 |
Design of mineral medium for growth of Actinomadura sp. ATCC 39727, producer of the glycopeptide A40926: effects of calcium ions and nitrogen sources.
Topics: Actinomycetales; Anti-Bacterial Agents; Asparagine; Biomass; Biotechnology; Calcium; Culture Media; Fermentation; Glucose; Glutamine; Glycopeptides; Microscopy, Fluorescence; Nitrogen; Phosphates; Quaternary Ammonium Compounds; Teicoplanin | 2004 |
Gln212, Asn270, and Arg301 are critical for catalysis by adenylosuccinate lyase from Bacillus subtilis.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Animals; Arginine; Asparagine; Bacillus subtilis; Binding Sites; Catalysis; Circular Dichroism; Glutamine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Sequence Alignment; Thermodynamics | 2004 |
Action of Pasteurella multocida toxin depends on the helical domain of Galphaq.
Topics: Amino Acid Sequence; Animals; Asparagine; Bacterial Proteins; Bacterial Toxins; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Genetic Vectors; Glutamine; GTP-Binding Protein alpha Subunits, Gq-G11; Histidine; Inositol Phosphates; Isoenzymes; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; Phospholipase C beta; Plasmids; Protein Structure, Tertiary; Recombinant Fusion Proteins; Retroviridae; Signal Transduction; Type C Phospholipases | 2004 |
Complete resonance assignments of the 'donor-strand complemented' AfaD: the afimbrial invasin from Diffusely Adherent E. coli.
Topics: Adhesins, Escherichia coli; Asparagine; Bacterial Adhesion; Cysteine; Escherichia coli; Genetic Complementation Test; Glutamine; Hydrogen-Ion Concentration; Integrins; Magnetic Resonance Spectroscopy; Oxygen; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Temperature; Valine | 2004 |
Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: implication for dimerization of nucleotide-binding domains to induce channel opening.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Dimerization; Glutamic Acid; Glutamine; Humans; Membrane Proteins; Mice; Mutation; Nicorandil; Nucleotides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Receptors, Drug; Sodium; Sulfonylurea Receptors | 2004 |
Identification of CC chemokine receptor 7 residues important for receptor activation.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Chemokine CCL19; Chemokine CCL21; Chemokines, CC; Chemotaxis; CHO Cells; COS Cells; Cricetinae; Dose-Response Relationship, Drug; Electroporation; Glutamine; Guanine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inhibitory Concentration 50; Jurkat Cells; Ligands; Lysine; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, CCR7; Receptors, Chemokine; Sequence Homology, Amino Acid; Time Factors; Transfection; Tyrosine | 2004 |
Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Catalytic Domain; Chickens; Cross-Linking Reagents; Crystallography, X-Ray; DNA; DNA Methylation; Fungal Proteins; Gene Silencing; Glutamine; Histone-Lysine N-Methyltransferase; Histones; Hydrogen-Ion Concentration; Lysine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Nucleosomes; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Ultraviolet Rays | 2004 |
Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro.
Topics: Alleles; Amyloid; Asparagine; Glutamine; Peptide Termination Factors; Prions; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors | 2004 |
Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Child; Child, Preschool; Delayed-Action Preparations; Female; Glutamine; Humans; Immunophenotyping; Male; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2004 |
The enzyme catalyzed exchange of ammonia with the amide group of glutamine and asparagine.
Topics: Amides; Ammonia; Ammonium Compounds; Asparagine; Enzymes; Glutamine; Quaternary Ammonium Compounds | 1950 |
Kinetic analysis of the individual steps of protein splicing for the Pyrococcus abyssi PolII intein.
Topics: Asparagine; Dithiothreitol; DNA Polymerase II; Electrophoresis, Polyacrylamide Gel; Glutamine; Hydrogen-Ion Concentration; Inteins; Kinetics; Models, Chemical; Peptides; Plasmids; Protein Splicing; Protein Structure, Tertiary; Pyrococcus abyssi; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2005 |
4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Asparagine; Cell Proliferation; D-Amino-Acid Oxidase; DNA Fragmentation; Fibroblasts; Glutamine; HeLa Cells; Humans; Liver; Methionine; Pyridoxal; Pyridoxamine; Rats; Transaminases | 2004 |
Gradually glycosylated protein C mutants (Arg178Gln and Cys331Arg) are degraded by proteasome after mannose trimming.
Topics: Animals; Arginine; Asparagine; Binding Sites; CHO Cells; Cricetinae; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Genetic Vectors; Glucose; Glutamine; Glycosylation; Immunoprecipitation; Mannose; Mutation; Oligosaccharides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein C; Recombinant Proteins; Time Factors; Transfection | 2004 |
The active site of L-asparaginase: dimethylsulfoxide effect of 5-diazo-4-oxo-L-norvaline interactions.
Topics: Aminolevulinic Acid; Asparaginase; Asparagine; Binding Sites; Dimethyl Sulfoxide; Enzyme Activation; Escherichia coli; Glutamine; Hydrolysis; Kinetics | 1976 |
Induction of class-1 non-symbiotic hemoglobin genes by nitrate, nitrite and nitric oxide in cultured rice cells.
Topics: Asparagine; Cells, Cultured; Cycloheximide; Gene Expression Regulation, Plant; Glutamine; Hemoglobins; Mannose-Binding Lectins; Nitrates; Nitric Oxide; Nitrites; Oryza; Plant Lectins; Protein Synthesis Inhibitors; RNA, Messenger | 2005 |
In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.
Topics: Amides; Animals; Antibodies, Monoclonal; Asparagine; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Liquid; Glutamine; Humans; Immunoglobulin G; Immunosorbent Techniques; Kinetics; Macaca fascicularis; Tandem Mass Spectrometry; Temperature | 2005 |
The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion.
Topics: Alternative Splicing; Animals; Asparagine; Embryo, Mammalian; Exons; Fertility; Glutamine; Lipid Metabolism; Lipids; Lysosomes; Male; Mice; Mice, Mutant Strains; Protein Isoforms; RNA, Messenger; Saposins; Sequence Deletion; Stem Cells; Testis; Tissue Distribution | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Asparagine and glutamine side-chain conformation in solution and crystal: a comparison for hen egg-white lysozyme using residual dipolar couplings.
Topics: Animals; Asparagine; Crystallography, X-Ray; Glutamine; Muramidase; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Solutions | 2004 |
NAD deamidation "a new reaction" by an enzyme from Aspergillus terreus DSM 826.
Topics: Acetamides; Acrylic Resins; Asparagine; Aspergillus; Chromatography, Liquid; Deamination; Enzyme Inhibitors; Enzyme Stability; Freezing; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; Niacinamide; Nicotinamide Mononucleotide; Pyridinium Compounds; Substrate Specificity; Temperature | 2005 |
Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Ions; Membrane Fusion; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Salts; Severe acute respiratory syndrome-related coronavirus; Spike Glycoprotein, Coronavirus; Static Electricity; Thermodynamics; Viral Envelope Proteins | 2005 |
15N/14N position-specific isotopic analyses of polynitrogenous amino acids.
Topics: Amino Acids; Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Lysine; Nitrogen Isotopes; Reproducibility of Results | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
A novel A*24 allele, A*2442, was detected through routine bone marrow donor screening.
Topics: Alleles; Asparagine; Base Sequence; Bone Marrow; DNA Primers; Exons; Female; Glutamine; Heterozygote; Histidine; HLA-A Antigens; HLA-A24 Antigen; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Tissue Banks; Tissue Donors | 2005 |
Protein misfolding and amyloid formation for the peptide GNNQQNY from yeast prion protein Sup35: simulation by reaction path annealing.
Topics: Amyloid; Asparagine; Computer Simulation; Glutamine; Models, Molecular; Peptide Fragments; Peptide Termination Factors; Prions; Protein Folding; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins; Water | 2005 |
Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch.
Topics: Alanine; Amino Acid Substitution; Arginine; Asparagine; Base Pair Mismatch; Binding Sites; DNA Polymerase I; DNA Primers; DNA-Binding Proteins; DNA, Single-Stranded; Escherichia coli Proteins; Exonucleases; Glutamine; Hydrolysis; Kinetics; Multienzyme Complexes; Protein Structure, Secondary; Templates, Genetic | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Amino Acid Sequence; Asparagine; Catalytic Domain; Glutamine; Guanosine Triphosphate; Isoenzymes; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Substrate Specificity | 2005 |
Difference FTIR studies reveal nitrogen-containing amino acid side chains are involved in the allosteric regulation of RecA.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Amino Acids; Arginine; Asparagine; Binding Sites; DNA-Binding Proteins; Escherichia coli Proteins; Glutamine; Hydrolysis; Lysine; Nitrogen; Nitrogen Isotopes; Protein Binding; Protein Conformation; Rec A Recombinases; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2005 |
Characterization of salt-tolerant glutaminase from Stenotrophomonas maltophilia NYW-81 and its application in Japanese soy sauce fermentation.
Topics: Amino Acid Sequence; Asparagine; Aspergillus oryzae; Chromatography, Gel; DNA, Bacterial; DNA, Ribosomal; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Fermentation; Glutamic Acid; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Micrococcus luteus; Molecular Sequence Data; Molecular Weight; Pseudomonas; Saline Solution, Hypertonic; Soy Foods; Stenotrophomonas maltophilia; Substrate Specificity; Temperature | 2005 |
Change in content of sugars and free amino acids in potato tubers under short-term storage at low temperature and the effect on acrylamide level after frying.
Topics: Acrylamide; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Cold Temperature; Color; Cooking; Food Handling; Food Preservation; Fructose; Glucose; Glutamic Acid; Glutamine; Solanum tuberosum; Time Factors | 2005 |
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine | 2005 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
Effect of deamidation on stability for the collagen to gelatin transition.
Topics: Amides; Asparagine; Circular Dichroism; Collagen; Drug Stability; Gelatin; Glutamine; Hot Temperature; Peptides; Protein Folding | 2005 |
Two rings of negative charges in the cytosolic vestibule of type-1 ryanodine receptor modulate ion fluxes.
Topics: Amino Acid Motifs; Animals; Asparagine; Biophysical Phenomena; Biophysics; Calcium; Cations; Cell Line; Cytosol; DNA, Complementary; Glutamic Acid; Glutamine; Humans; Ions; Kinetics; Lipid Bilayers; Models, Molecular; Muscle, Skeletal; Mutation; Neomycin; Potassium; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2006 |
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.
Topics: Animals; Asparagine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Endoplasmic Reticulum; Fungal Proteins; Gene Expression Profiling; Glutamine; Heat-Shock Proteins; Longevity; Resveratrol; RNA Interference; Sirtuins; Stilbenes; Transcription, Genetic | 2005 |
The amino terminus and the third extracellular loop of CX3CR1 contain determinants critical for distinct receptor functions.
Topics: Amino Acid Sequence; Asparagine; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Chemotaxis; CX3C Chemokine Receptor 1; Glutamine; Humans; Ligands; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Mutation; Phosphorylation; Protein Structure, Tertiary; Receptors, Chemokine; Signal Transduction; Tyrosine | 2006 |
Contribution of conserved polar glutamine, asparagine and threonine residues and glycosylation to agonist action at human P2X1 receptors for ATP.
Topics: Adenosine Triphosphate; Animals; Asparagine; Dose-Response Relationship, Radiation; Electric Stimulation; Glutamine; Glycosylation; Humans; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Point Mutation; Receptors, Purinergic P2; Receptors, Purinergic P2X; Structure-Activity Relationship; Threonine; Xenopus | 2006 |
Exchange of glutamine-217 to glutamate of Clostridium limosum exoenzyme C3 turns the asparagine-specific ADP-ribosyltransferase into an arginine-modifying enzyme.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Arginine; Asparagine; Botulinum Toxins; Clostridium; Escherichia coli; Glutamic Acid; Glutamine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Trypsin Inhibitor, Bowman-Birk Soybean | 2006 |
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
Topics: Adenocarcinoma; Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Xeroderma Pigmentosum Group D Protein | 2007 |
A novel-type substrate-selectivity filter and ER-exit determinants in the UapA purine transporter.
Topics: Amino Acid Substitution; Asparagine; Aspergillus nidulans; DNA Mutational Analysis; Endoplasmic Reticulum; Fungal Proteins; Glutamine; Kinetics; Membrane Transport Proteins; Phenylalanine; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Substrate Specificity | 2006 |
The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome.
Topics: Adult; Arginine; Asparagine; Aspartic Acid; Case-Control Studies; Female; Fertilization; Fertilization in Vitro; Gene Frequency; Genetic Variation; Genotype; Glutamine; Humans; Infertility; Mutation; Pregnancy; Pregnancy Rate; Treatment Outcome; UDPglucose-Hexose-1-Phosphate Uridylyltransferase | 2006 |
NQ-Flipper: validation and correction of asparagine/glutamine amide rotamers in protein crystal structures.
Topics: Asparagine; Crystallography; Data Interpretation, Statistical; Databases, Protein; Escherichia coli; Glutamine; Internet; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Folding; Reproducibility of Results; Software; Thermodynamics | 2006 |
Proposal for a hydrogen bond network in the active site of the prototypic gamma-class carbonic anhydrase.
Topics: Asparagine; Binding Sites; Carbonic Anhydrases; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary; Spectrum Analysis | 2006 |
Self-consistent assignment of asparagine and glutamine amide rotamers in protein crystal structures.
Topics: Amides; Asparagine; Crystallography; Databases, Protein; Glutamine; Models, Structural; Protein Conformation; Stereoisomerism | 2006 |
Ammonia channel couples glutaminase with transamidase reactions in GatCAB.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Aminoacyltransferases; Ammonia; Apoenzymes; Asparagine; Base Pairing; Catalytic Domain; Crystallography, X-Ray; Glutaminase; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Magnesium; Manganese; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; RNA, Bacterial; RNA, Transfer, Amino Acyl; RNA, Transfer, Gln; Staphylococcus aureus | 2006 |
Vibrational spectra of the Cu(II) complexes of L-asparagine and L-glutamine.
Topics: Amides; Asparagine; Copper Sulfate; Glutamine; Ligands; Spectrum Analysis, Raman | 2007 |
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; Cisplatin; Cysteine; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Female; Gene Frequency; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Female; Glutamine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Protein Serine-Threonine Kinases; Wolinella | 2006 |
Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Baculoviridae; Binding Sites; Catalytic Domain; Cell Line, Tumor; Genetic Vectors; Glutamic Acid; Glutamine; Histidine; Humans; Nucleotides; Protein Transport | 2006 |
Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Glutamine; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Protein Structure, Secondary; Valine; Xanthine | 2006 |
Direct analysis of 15N-label in amino and amide groups of glutamine and asparagine.
Topics: Asparagine; Chromatography, High Pressure Liquid; Glutamine; Isotope Labeling; Nitrogen Isotopes; Spectrometry, Mass, Electrospray Ionization | 2007 |
Conducting polymers in modelling transient potential of biological membranes.
Topics: Adenosine Triphosphate; Asparagine; Calcium; Cations, Divalent; Cell Membrane; Diffusion; Electrochemistry; Glutamine; Heparin; Ion Exchange; Ligands; Magnesium; Models, Biological; Polymers; Pyrroles; Sensitivity and Specificity; Solutions; Spectrum Analysis; Surface Properties; Time Factors | 2007 |
Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.
Topics: Adult; Amino Acid Substitution; Arsenic; Asparagine; Aspartic Acid; Case-Control Studies; Female; Genetic Predisposition to Disease; Glutamine; Humans; Lysine; Male; Polymorphism, Single Nucleotide; Skin Diseases; Sunburn; Water Supply; Xeroderma Pigmentosum Group D Protein | 2007 |
NQ-Flipper: recognition and correction of erroneous asparagine and glutamine side-chain rotamers in protein structures.
Topics: Asparagine; Computational Biology; Crystallography; Data Interpretation, Statistical; Databases, Protein; Glutamine; Internet; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Folding; Proteins; Reproducibility of Results; Software; Thermodynamics | 2007 |
Hematological and molecular characteristics of Hb Sarrebourg [beta131(H9)Gln-->Arg (CAG-->CGG)] found in a Spanish family.
Topics: Amino Acid Substitution; Asparagine; Female; Globins; Glutamine; Hemoglobins, Abnormal; Humans; Male; Pedigree; Polymorphism, Single Nucleotide; Spain | 2007 |
Overexpression of BACE1 stimulates spontaneous basal secretion in PC12 cells.
Topics: Amyloid Precursor Protein Secretases; Animals; Asparagine; Aspartic Acid Endopeptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glutamine; Growth Hormone; Humans; Mutation; Norepinephrine; PC12 Cells; Potassium Chloride; Rats; Time Factors; Transfection | 2007 |
Molecular characterization of cold adaptation based on ortholog protein sequences from Vibrionaceae species.
Topics: Acclimatization; Alanine; Aliivibrio salmonicida; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacterial Proteins; Cold Temperature; Computational Biology; Databases, Genetic; Glutamine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Protein Conformation; Sequence Alignment; Surface Properties; Vibrionaceae | 2007 |
A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast.
Topics: Asparagine; Detergents; Gene Deletion; Glutamine; Heat-Shock Proteins; Podospora; Prions; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sarcosine | 2007 |
Effect of liposome characteristics and dose on the pharmacokinetics of liposomes coated with poly(amino acid)s.
Topics: Animals; Asparagine; Cholesterol; Glutamine; Injections, Intravenous; Lipids; Liposomes; Male; Membrane Fluidity; Particle Size; Rats; Rats, Wistar; Succinimides; Surface Properties | 2007 |
Glutamine phosphoribosylpyrophosphate amidotransferase-independent phosphoribosyl amine synthesis from ribose 5-phosphate and glutamine or asparagine.
Topics: Acid Phosphatase; Amidophosphoribosyltransferase; Asparagine; Escherichia coli; Escherichia coli Proteins; Glutamine; Periplasmic Proteins; Ribosemonophosphates; Salmonella enterica | 2007 |
Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae.
Topics: Asparagine; Cytoplasm; Glutamine; Models, Biological; Oligonucleotides; Protein Biosynthesis; Protein Structure, Tertiary; Ribonucleoprotein, U4-U6 Small Nuclear; Ribonucleoproteins; RNA Stability; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Two-Hybrid System Techniques | 2007 |
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Topics: Acetylcholinesterase; Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutamine; Isoleucine; Leucine; Mice; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Stereoisomerism; Terbutaline; Tyrosine | 2008 |
Methanothermobacter thermautotrophicus tRNA Gln confines the amidotransferase GatCAB to asparaginyl-tRNA Asn formation.
Topics: Asparagine; Bacillus subtilis; Glutamine; Helicobacter pylori; Methanobacterium; Nitrogenous Group Transferases; RNA, Transfer, Asn; RNA, Transfer, Gln | 2008 |
Experimental and theoretical studies of sodium cation complexes of the deamidation and dehydration products of asparagine, glutamine, aspartic acid, and glutamic acid.
Topics: Amides; Amino Acids; Asparagine; Aspartic Acid; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Sodium; Thermodynamics; Water | 2008 |
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.
Topics: Animals; Arginine; Asparagine; Disease Models, Animal; Female; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Nipecotic Acids; PC12 Cells; Rats; Tiagabine | 2008 |
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease.
Topics: Animals; Asparagine; Cell Differentiation; Cell Movement; Disease Models, Animal; Disease Progression; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Sertraline | 2008 |
SO-LAAO, a novel L-amino acid oxidase that enables Streptococcus oligofermentans to outcompete Streptococcus mutans by generating H2O2 from peptone.
Topics: Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Glutamine; Hydrogen Peroxide; Isoleucine; L-Amino Acid Oxidase; Molecular Sequence Data; Mutation; Peptones; Sequence Homology, Amino Acid; Streptococcus; Streptococcus mutans; Tryptophan | 2008 |
Novel mutations in the TK2 gene associated with fatal mitochondrial DNA depletion myopathy.
Topics: Asparagine; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Glutamine; Humans; Infant; Male; Mitochondrial Myopathies; Multienzyme Complexes; Muscle, Skeletal; Mutation; Serine; Thymidine Kinase | 2008 |
A role for Q/N-rich aggregation-prone regions in P-body localization.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Cytoplasm; Cytoplasmic Granules; Glutamine; Molecular Sequence Data; Ribonucleoprotein, U4-U6 Small Nuclear; RNA Stability; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2008 |
Comparison of nitrogen narcosis and helium pressure effects on striatal amino acids: a microdialysis study in rats.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Glutamic Acid; Glutamine; Helium; Inert Gas Narcosis; Male; Microdialysis; Nitrogen; Pressure; Rats; Rats, Sprague-Dawley | 2009 |
An isocratic fluorescence HPLC assay for the monitoring of l-asparaginase activity and l-asparagine depletion in children receiving E. colil-asparaginase for the treatment of acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli Proteins; Fluorescence; Glutamic Acid; Glutamine; Homoserine; Humans; Least-Squares Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population.
Topics: Adult; Age Factors; Aged; Alleles; Asparagine; Case-Control Studies; Coronary Artery Disease; Endothelium, Vascular; Exons; Female; Glutamine; Greece; Humans; Introns; Male; Middle Aged; Minisatellite Repeats; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors | 2008 |
Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation.
Topics: Animals; Asparagine; Cations, Divalent; Computer Simulation; Copper; Cysteine; Dimerization; Glutamine; Humans; Models, Chemical; Protein Folding; Protein Structure, Secondary; Superoxide Dismutase; Superoxide Dismutase-1; Thermodynamics; Zinc | 2008 |
Effects of genotype and environment on free amino acid levels in wheat grain: implications for acrylamide formation during processing.
Topics: Acrylamide; Amino Acids; Asparagine; Crosses, Genetic; Environment; Flour; Food Handling; Genotype; Glutamine; Hot Temperature; Seeds; Triticum | 2009 |
Molecular mechanism of the interaction between activated factor XIII and its glutamine donor peptide substrate.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Factor XIIIa; Glutamine; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Peptides; Protein Binding; Substrate Specificity | 2009 |
Inoculation of sugarcane with Pantoea sp. increases amino acid contents in shoot tissues; serine, alanine, glutamine and asparagine permit concomitantly ammonium excretion and nitrogenase activity of the bacterium.
Topics: Alanine; Amino Acids; Asparagine; Bacterial Proteins; Glutamine; Nitrogenase; Pantoea; Quaternary Ammonium Compounds; Saccharum; Serine | 2009 |
Participation of asparagine 370 and glutamine 235 in the catalysis by acid beta-glucosidase: the enzyme deficient in Gaucher disease.
Topics: 2,4-Dinitrophenol; Amino Acid Substitution; Asparagine; Azides; Biocatalysis; Catalytic Domain; Enzyme Activation; Gaucher Disease; Glucosylceramidase; Glutamine; Glycosylation; Hydrogen-Ion Concentration; Hydrolysis; Mutant Proteins; Phosphatidylserines; Structure-Activity Relationship; Substrate Specificity; Taurocholic Acid | 2009 |
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Cytosol; Genome, Fungal; Glutamine; Heat-Shock Proteins; Molecular Sequence Data; Peptide Termination Factors; Phenotype; Prions; Proteome; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 2009 |
Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases.
Topics: Animals; Asparagine; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Structure, Tertiary; Protein Transport; RNA-Binding Proteins; Solubility | 2009 |
Effective amino acid composition of seaweeds inducing food preference behaviors in Aplysia kurodai.
Topics: Amino Acids; Animals; Aplysia; Asparagine; Aspartic Acid; Eating; Food Preferences; Glutamic Acid; Glutamine; Jaw; Phaeophyceae; Phenylalanine; Rhodophyta; Taste; Taurine; Ulva | 2009 |
Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine.
Topics: Amidohydrolases; Animals; Asparagine; Catalysis; Deamination; Glutamine; Ketoglutaric Acids; Liver; Rats; Spectrophotometry | 2009 |
Impact of bulking agents on the stability of a lyophilized monoclonal antibody.
Topics: Amides; Antibodies, Monoclonal; Asparagine; Calorimetry, Differential Scanning; Chromatography, Gel; Excipients; Freeze Drying; Glutamine; Glycine; Mannose; Pharmaceutic Aids; Protein Stability; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Sucrose; Transition Temperature; Tumor Necrosis Factor-alpha; Water | 2009 |
Demonstration of catalytic proton acceptor of chitosanase from Paenibacillus fukuinensis by comprehensive analysis of mutant library.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Chitosan; DNA Mutational Analysis; Glucans; Glutamine; Glycoside Hydrolases; Models, Molecular; Mutagenesis, Site-Directed; Paenibacillus; Protein Structure, Tertiary; Protons | 2009 |
Insights into tRNA-dependent amidotransferase evolution and catalysis from the structure of the Aquifex aeolicus enzyme.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteria; Catalysis; Catalytic Domain; Crystallography, X-Ray; Evolution, Molecular; Genetic Complementation Test; Glutamine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nitrogenous Group Transferases; Protein Structure, Quaternary; RNA, Transfer; Substrate Specificity; Zinc | 2009 |
tRNA-dependent cysteine biosynthetic pathway represents a strategy to increase cysteine contents by preventing it from thermal degradation: thermal adaptation of methanogenic archaea ancestor.
Topics: Adaptation, Physiological; Archaea; Asparagine; Cysteine; Glutamine; Hot Temperature; Methane; RNA, Transfer, Amino Acyl | 2009 |
Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination.
Topics: Amidohydrolases; Aminohydrolases; Animals; Asparagine; Electrophoresis, Polyacrylamide Gel; Glutamine; Humans; Ketoglutaric Acids; Kinetics; Liver; Mice; Mice, Knockout; Protein Subunits; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
How can an inert gas counterbalance a NMDA-induced glutamate release?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Asparagine; Aspartic Acid; Catheters, Indwelling; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Homovanillic Acid; Inert Gas Narcosis; Male; Microdialysis; N-Methylaspartate; Nitrogen; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric | 2009 |
Compositional determinants of prion formation in yeast.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Molecular Sequence Data; Mutagenesis; Peptide Termination Factors; Prions; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2010 |
Role of asparagine-linked glycosylation in cell surface expression and function of the human adrenocorticotropin receptor (melanocortin 2 receptor) in 293/FRT cells.
Topics: Asparagine; Cell Line; Codon; Cyclic AMP; DNA Nucleotidyltransferases; Glutamine; Glycosylation; Humans; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Receptor, Melanocortin, Type 2; Transfection | 2010 |
Age-dependent deamidation of lifelong proteins in the human lens.
Topics: Aged; Aged, 80 and over; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Gestational Age; Glutamine; Humans; Lens, Crystalline; Middle Aged; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Regulation of synaptic Pumilio function by an aggregation-prone domain.
Topics: Amyloid; Animals; Animals, Genetically Modified; Asparagine; Base Sequence; Computational Biology; Drosophila; Drosophila Proteins; Fungal Proteins; Gene Expression Regulation; Gene Expression Regulation, Fungal; Glutamine; Green Fluorescent Proteins; Larva; Luminescent Proteins; Microscopy, Electron, Transmission; Molecular Sequence Data; Muscles; Neuromuscular Junction; Presynaptic Terminals; Protein Binding; Receptors, AMPA; RNA-Binding Proteins; Sequence Homology, Amino Acid | 2010 |
Embryo and larva development in common dentex (Dentex dentex), a pelagophil teleost: the quantitative composition of egg-free amino acids and their interrelations.
Topics: Amino Acids; Animals; Arginine; Asparagine; Embryonic Development; Female; Glutamic Acid; Glutamine; Larva; Male; Oocytes; Perciformes | 2010 |
A pressurized nitrogen counterbalance to cortical glutamatergic pathway stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Asparagine; Aspartic Acid; Baclofen; Corpus Striatum; Dopamine; Glutamic Acid; Glutamine; Homovanillic Acid; Hyperbaric Oxygenation; Inert Gas Narcosis; Male; Nitrogen; Pressure; Rats; Rats, Sprague-Dawley | 2010 |
Identification of genes regulated by ammonium availability in the roots of maritime pine trees.
Topics: Amino Acids; Asparagine; Gene Expression Regulation, Plant; Genes, Plant; Glutamine; Pinus; Plant Roots; Polymerase Chain Reaction; Protein Array Analysis; Quaternary Ammonium Compounds; RNA, Plant; Signal Transduction; Stress, Physiological; Tracheophyta; Transcription, Genetic | 2010 |
Synthesis of mono-ADP-ribosylated oligopeptides using ribosylated amino acid building blocks.
Topics: Adenosine Diphosphate Ribose; Asparagine; Glutamine; Molecular Structure; Oligopeptides; Stereoisomerism | 2010 |
Studies on the effect of pyruvate on the desamidation of glutamine, asparagine, and related compounds.
Topics: Amino Acids; Asparagine; Enzymes; Glutamine; Pyruvates; Pyruvic Acid | 1947 |
Desamidation of glutamine and asparagine in normal and neoplastic hepatic tissues.
Topics: Amino Acids; Asparagine; Glutamine; Liver Neoplasms; Neoplasms | 1947 |
Effect of heating on the capacity of rat liver extracts to desamidate glutamine and asparagine.
Topics: Amino Acids; Animals; Asparagine; Glutamine; Heating; Hot Temperature; Liver; Liver Extracts; Rats | 1947 |
Effects of acidity and of heating on the capacity of rat liver extracts to desamidate glutamine and asparagine.
Topics: Amino Acids; Animals; Asparagine; Glutamine; Heating; Liver; Liver Extracts; Rats | 1947 |
Relation between pH and the effect of pyruvate on the desamidation of glutamine and asparagine.
Topics: Amino Acids; Asparagine; Biochemical Phenomena; Glutamine; Hydrogen-Ion Concentration; Pyruvates; Pyruvic Acid | 1947 |
Deglycosylation of FcalphaR at N58 increases its binding to IgA.
Topics: Animals; Antigens, CD; Asparagine; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Glutamine; Immunoglobulin A; Mutagenesis, Site-Directed; Rats; Receptors, Fc | 2010 |
Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.
Topics: Amyotrophic Lateral Sclerosis; Asparagine; Cell Line; Cell Nucleus; DNA-Binding Proteins; Glutamine; Humans; Multiprotein Complexes; Peptides; Protein Multimerization | 2010 |
Porous lanthanide oxides via a precursor method: morphology control through competitive interaction of lanthanide cations with oxalate anions and amino acids.
Topics: Amino Acids; Asparagine; Coordination Complexes; Glutamine; Hydrogen-Ion Concentration; Lanthanoid Series Elements; Microscopy, Electron, Scanning; Oxalates; Oxides; Porosity; Spectrometry, Mass, Electrospray Ionization; Temperature | 2010 |
Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function.
Topics: Amino Acid Motifs; Amyloid; Asparagine; Chromosomal Proteins, Non-Histone; Chromosome Deletion; Chromosomes, Fungal; Glutamine; Immunoblotting; Luminescent Proteins; Microscopy, Confocal; Microscopy, Electron; Mutation; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 2010 |
Structural and mechanistic Information on c(1) ion formation in collision-induced fragmentation of peptides.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Molecular Sequence Data; Ornithine; Peptides; Tandem Mass Spectrometry | 2010 |
Accelerated removal of deamidated proteins and endogenous electric fields: possible implications.
Topics: Aging; Asparagine; Biophysical Phenomena; Electricity; Glutamine; Isoelectric Point; Models, Biological; Peptide Hydrolases; Protein Folding; Proteins | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
An αIIb mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the β-propeller (Asn2Asp) disrupts a calcium binding site in blade 6.
Topics: Adolescent; Amino Acid Sequence; Animals; Arabs; Asparagine; Aspartic Acid; Binding Sites; Blood Platelets; Calcium; Cell Line; Child; Child, Preschool; Cricetinae; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glutamine; Hemostasis; Heredity; Humans; Hydrogen Bonding; Integrin alpha2; Integrin beta3; Israel; Leucine; Male; Models, Molecular; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Thrombasthenia; Transfection | 2011 |
An economical method for producing stable-isotope labeled proteins by the E. coli cell-free system.
Topics: Amino Acids; Asparagine; Cysteine; Escherichia coli; Glutamine; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Biosynthesis; Proteins; Tryptophan | 2010 |
Deamidation at asparagine and glutamine as a major modification upon deterioration/aging of proteinaceous binders in mural paintings.
Topics: Amides; Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Paintings; Peptide Fragments; Proteins; Time Factors | 2011 |
Yeast prion protein New1 can break Sup35 amyloid fibrils into fragments in an ATP-dependent manner.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amyloid; Asparagine; Binding Sites; Blotting, Western; Glutamine; Green Fluorescent Proteins; Heat-Shock Proteins; Mutation; Peptide Termination Factors; Prions; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2011 |
A sister group contrast using untargeted global metabolomic analysis delineates the biochemical regulation underlying desiccation tolerance in Sporobolus stapfianus.
Topics: Adaptation, Physiological; Allantoin; Asparagine; Citric Acid Cycle; Desiccation; Glutamine; Glutathione; Glycolysis; Metabolome; Metabolomics; Nitrogen; Phenotype; Poaceae; Raffinose; Tocopherols; Water | 2011 |
Protein kinase C-mediated phosphorylation of a single serine residue on the rat glial glutamine transporter SN1 governs its membrane trafficking.
Topics: Amino Acid Transport Systems, Neutral; Animals; Asparagine; Biotinylation; Chlorocebus aethiops; Computational Biology; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamine; Histones; Immunoprecipitation; Indoles; Male; Maleimides; Membrane Potentials; Models, Molecular; Oocytes; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Point Mutation; Protein Isoforms; Protein Kinase C; Protein Transport; Qa-SNARE Proteins; Rats; Rats, Wistar; Serine; Transfection; Xenopus laevis | 2011 |
Systematic examination of polymorphism in amyloid fibrils by molecular-dynamics simulation.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Glutamine; Hydrogen Bonding; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Protein Stability; Protein Structure, Quaternary; Static Electricity; Surface Properties; Thermodynamics | 2011 |
A small, glutamine-free domain propagates the [SWI(+)] prion in budding yeast.
Topics: Asparagine; Glutamine; Peptide Fragments; Prions; Saccharomycetales | 2011 |
Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Glutamine; Molecular Sequence Data; Peptide Termination Factors; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, Protein | 2011 |
A new approach to obtaining Nα -t-Boc-amino acid aldehydes from asparagine and glutamine for reduced amide pseudopeptide solid-phase synthesis.
Topics: Aldehydes; Amides; Asparagine; Glutamine; Oxidation-Reduction; Solid-Phase Synthesis Techniques | 2011 |
Detection, evaluation and minimization of nonenzymatic deamidation in proteomic sample preparation.
Topics: Amides; Analytic Sample Preparation Methods; Animals; Asparagine; Chromatography, Liquid; False Positive Reactions; Glutamine; Glycosylation; Peptide Fragments; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Proteolysis; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Trypsin | 2011 |
Pitfalls in protein quantitation using acid-catalyzed O18 labeling: hydrolysis-driven deamidation.
Topics: Acids; Amino Acid Sequence; Asparagine; Catalysis; Chromatography, High Pressure Liquid; Deamination; Glutamine; Humans; Hydrolysis; Isotope Labeling; Mass Spectrometry; Oxygen Isotopes; Proteins; Transferrin | 2011 |
Elucidation of degradants in acidic peak of cation exchange chromatography in an IgG1 monoclonal antibody formed on long-term storage in a liquid formulation.
Topics: Animals; Antibodies, Monoclonal; Asparagine; Aspartic Acid; Chemistry, Pharmaceutical; CHO Cells; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Liquid; Chromatography, Reverse-Phase; Complementarity Determining Regions; Cricetinae; Drug Stability; Drug Storage; Glutamine; Glycosylation; Histocompatibility Antigens Class I; Humans; Immunoglobulin G; Isoelectric Focusing; Mass Spectrometry; Peptide Mapping; Receptors, Fc; Temperature; Trypsin | 2012 |
Introduction of glutamines into the B2-H2 loop promotes prion protein conversion.
Topics: Amino Acid Sequence; Amyloid; Animals; Asparagine; Glutamine; Mice; Molecular Sequence Data; Mutation; Protein Folding; Protein Structure, Secondary; PrPC Proteins; PrPSc Proteins | 2011 |
In silico engineering of L-asparaginase to have reduced glutaminase side activity for effective treatment of acute lymphoblastic leukemia.
Topics: Asparaginase; Asparagine; Catalytic Domain; Child; Computer Simulation; Drug Design; Glutaminase; Glutamine; Humans; Ligands; Mutagenesis, Site-Directed; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Engineering | 2011 |
An engineered pathway for glyoxylate metabolism in tobacco plants aimed to avoid the release of ammonia in photorespiration.
Topics: Aldose-Ketose Isomerases; Ammonia; Asparagine; Carboxy-Lyases; Cell Respiration; Escherichia coli; Escherichia coli Proteins; Gene Transfer Techniques; Genetic Engineering; Glutamine; Glyoxylates; Nicotiana; Nitrogen Cycle; Plant Leaves; Plants, Genetically Modified | 2011 |
Role of N-glycosylation in cell surface expression and protection against proteolysis of the intestinal anion exchanger SLC26A3.
Topics: Amino Acid Substitution; Animals; Asparagine; Cell Membrane; Chloride-Bicarbonate Antiporters; CHO Cells; Congenital Disorders of Glycosylation; Cricetinae; Cricetulus; Glutamine; Glycoside Hydrolases; Glycosylation; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Mutagenesis, Site-Directed; Oligosaccharides; Proteolysis; Sulfate Transporters | 2012 |
Evidence for a new post-translational modification in Staphylococcus aureus: hydroxymethylation of asparagine and glutamine.
Topics: Asparagine; Bacterial Proteins; Chromatography, Liquid; Glutamine; Membrane Proteins; Protein Processing, Post-Translational; Staphylococcus aureus; Tandem Mass Spectrometry | 2012 |
Asparagine and glutamine differ in their propensities to form specific side chain-backbone hydrogen bonded motifs in proteins.
Topics: Amino Acid Motifs; Asparagine; Computational Biology; Glutamine; Histidine; Hydrogen Bonding; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Proteins | 2012 |
The kinase activity of the Helicobacter pylori Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase is sensitive to distal mutations in its putative ammonia tunnel.
Topics: Ammonia; Asparagine; Aspartate-tRNA Ligase; Enzyme Activation; Glutamine; Helicobacter pylori; Lysine; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrogenous Group Transferases; Phosphorylation; RNA, Transfer, Amino Acyl; Staphylococcus aureus; Tyrosine | 2012 |
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide | 2012 |
Asparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin-Frankfurt-Münster-based induction therapy for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Child; Child, Preschool; Daunorubicin; Drug Administration Schedule; Female; Glutamic Acid; Glutamine; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Time Factors; Treatment Outcome; Vincristine | 2012 |
Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT₇a receptor.
Topics: Adenylyl Cyclases; Asparagine; Glutamine; Glycosylation; HEK293 Cells; Humans; Mutation; Plasmids; Protein Binding; Radioligand Assay; Receptors, Serotonin; Serotonin; Transfection | 2012 |
The arbuscular mycorrhizal status has an impact on the transcriptome profile and amino acid composition of tomato fruit.
Topics: Asparagine; Carbohydrate Metabolism; Flowers; Fruit; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Glutamine; Molecular Sequence Annotation; Mycorrhizae; Nitrogen; RNA, Plant; Signal Transduction; Solanum lycopersicum; Symbiosis; Time Factors; Transcriptome | 2012 |
An update view on the substrate recognition mechanism of phosphodiesterases: a computational study of PDE10 and PDE4 bound with cyclic nucleotides.
Topics: Asparagine; Binding Sites; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Databases, Protein; Glutamine; Humans; Hydrogen Bonding; Isoenzymes; Kinetics; Molecular Dynamics Simulation; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Temperature; Thermodynamics | 2012 |
Nitrogen nutrition in the cyanobacterium Nostoc ANTH, a symbiotic isolate from Anthoceros: uptake and assimilation of inorganic-n and amino acids.
Topics: Amino Acids; Anthocerotophyta; Arginine; Asparagine; Culture Media; Cyanobacteria; Gene Expression Regulation, Bacterial; Glutamate-Ammonia Ligase; Glutamine; Inorganic Chemicals; Mutation; Nitrate Reductase; Nitrogen; Nitrogen Fixation; Nitrogenase; Quaternary Ammonium Compounds | 2002 |
Changes in the C/N balance caused by increasing external ammonium concentrations are driven by carbon and energy availabilities during ammonium nutrition in pea plants: the key roles of asparagine synthetase and anaplerotic enzymes.
Topics: Ammonium Compounds; Asparagine; Aspartate-Ammonia Ligase; Carbon; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Light; Nitrogen; Pisum sativum; Polyamines | 2013 |
Purification, characterization and kinetic properties of extracellular L-asparaginase produced by Cladosporium sp.
Topics: Asparaginase; Asparagine; Chromatography, Gel; Cladosporium; Culture Media; Electrophoresis, Polyacrylamide Gel; Enzyme Activators; Enzyme Inhibitors; Enzyme Stability; Glutamine; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Protein Multimerization; Substrate Specificity; Temperature | 2013 |
Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability.
Topics: Amyloid; Asparagine; Glutamine; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Molecular Chaperones; Peptide Termination Factors; Prions; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
High irradiance improves ammonium tolerance in wheat plants by increasing N assimilation.
Topics: Ammonium Compounds; Asparagine; Biomass; Carbohydrate Metabolism; Carbon; Citric Acid Cycle; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Nitrates; Nitrogen; Photosynthesis; Sunlight; Triticum | 2013 |
Molecular antagonism between X-chromosome and autosome signals determines nematode sex.
Topics: Amino Acid Motifs; Animals; Asparagine; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Nucleus; Chromosomes; DNA Transposable Elements; DNA-Binding Proteins; Dosage Compensation, Genetic; Embryo, Nonmammalian; Female; Gene Dosage; Gene Expression Regulation, Developmental; Genes, Helminth; Glutamine; Homeodomain Proteins; Male; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA-Binding Proteins; Sex Determination Processes; Transcription, Genetic; Transposases; X Chromosome | 2013 |
Schiff bases attached L-glutamine and L-asparagine: first investigation on antimutagenic and antimicrobial analyses.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimutagenic Agents; Asparagine; Bacteria; Candida albicans; Female; Glutamine; Humans; Lymphocytes; Male; Manganese; Micronucleus Tests; Schiff Bases | 2014 |
A bioinformatics method for identifying Q/N-rich prion-like domains in proteins.
Topics: Algorithms; Asparagine; Computational Biology; Glutamine; Humans; Internet; Prions; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sequence Analysis, Protein; Software | 2013 |
Spectroscopic identification of cyclic imide b2-ions from peptides containing Gln and Asn residues.
Topics: Amides; Asparagine; Glutamine; Imides; Lasers; Models, Molecular; Nitrogen; Oxazolone; Oxygen; Peptides; Piperazines; Piperidones; Spectrophotometry, Infrared; Succinimides; Tandem Mass Spectrometry | 2013 |
Ecological implications of single and mixed nitrogen nutrition in Arabidopsis thaliana.
Topics: Arabidopsis; Asparagine; Glutamine; Nitrates; Nitrogen; Nitrogen Isotopes; Reproduction | 2013 |
A facile synthesis of α-N-ribosyl-asparagine and α-N-ribosyl-glutamine building blocks.
Topics: Adenosine Diphosphate; Amino Acids; Asparagine; Chemistry Techniques, Synthetic; Glutamine; Glycosylation; Protein Processing, Post-Translational | 2013 |
Simulations of peptide-graphene interactions in explicit water.
Topics: Arginine; Asparagine; Computer Simulation; Glutamine; Graphite; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Dynamics Simulation; Peptides; Protein Conformation; Surface Properties; Water | 2013 |
Acidic amino acids increase fusion activity in the specific fusion domain of Newcastle disease virus fusion protein.
Topics: Animals; Asparagine; Cell Line; Glutamine; HN Protein; Membrane Fusion; Newcastle Disease; Newcastle disease virus; Point Mutation; Viral Fusion Proteins | 2013 |
Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation.
Topics: Amides; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Campylobacter jejuni; Campylobacter lari; Escherichia coli; Gene Expression; Glutamine; Glycosylation; Hexosyltransferases; Homoserine; Kinetics; Membrane Proteins; Models, Molecular; Protein Binding; Recombinant Proteins; Substrate Specificity | 2013 |
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance.
Topics: Amino Acid Sequence; Antibiotics, Antitubercular; Asparagine; Aspartic Acid; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Glutamic Acid; Glutamine; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Phenotype; Protein Biosynthesis; Proteomics; Recombination, Genetic; Rifampin | 2014 |
Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dacarbazine; DNA Damage; Drug Synergism; Glioblastoma; Glutamine; Humans; Male; Medulloblastoma; Mice; Mice, Nude; Temozolomide; Xenograft Model Antitumor Assays | 2014 |
Metal cation dependence of interactions with amino acids: bond dissociation energies of Rb(+) and Cs(+) to the acidic amino acids and their amide derivatives.
Topics: Asparagine; Aspartic Acid; Cations; Cesium; Computer Simulation; Entropy; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Potassium; Quantum Theory; Rubidium; Sodium; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Xenon | 2014 |
Increasing prion propensity by hydrophobic insertion.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Blotting, Western; Computational Biology; Glutamine; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Mutagenesis; Mutation; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Tyrosine | 2014 |
Cerebrospinal fluid asparagine depletion during pegylated asparaginase therapy in children with acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Child; Child, Preschool; Drug Administration Schedule; Drug Monitoring; Female; Glutamine; Humans; Infant; Injections, Intramuscular; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Specimen Handling | 2014 |
Selective (15)N-labeling of the side-chain amide groups of asparagine and glutamine for applications in paramagnetic NMR spectroscopy.
Topics: Asparagine; Escherichia coli; Escherichia coli Proteins; Glutamine; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular | 2014 |
Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Hep G2 Cells; Humans; Ki-67 Antigen; Liver Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Nude; Mutation; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Topics: Activating Transcription Factor 4; Apoptosis; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citrate (si)-Synthase; Citric Acid Cycle; Glutamine; Humans; Oxaloacetic Acid; RNA Interference; RNA, Small Interfering | 2014 |
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; Basidiomycota; Cell Proliferation; Glutamic Acid; Glutamine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleases; Structure-Activity Relationship | 2015 |
Asparagine protects tumor cells from glutamine depletion-induced cell death.
Topics: Asparagine; Aspartate-Ammonia Ligase; Cell Death; Glutamine; Humans; Neoplasms; Transcription Factor CHOP | 2014 |
Interaction of Bordetella adenylate cyclase toxin with complement receptor 3 involves multivalent glycan binding.
Topics: Adenylate Cyclase Toxin; Amino Acid Substitution; Asparagine; Bordetella pertussis; CD11b Antigen; CD18 Antigens; Glutamine; Glycosylation; Humans; Macrophage-1 Antigen; Polysaccharides; Protein Structure, Tertiary | 2015 |
Heterologous aggregates promote de novo prion appearance via more than one mechanism.
Topics: Asparagine; Cytoplasm; Glutamine; Molecular Chaperones; Prion Diseases; Prions; Protein Aggregates; Protein Conformation; Saccharomyces cerevisiae; Vacuoles | 2015 |
Does deamidation cause protein unfolding? A top-down tandem mass spectrometry study.
Topics: Amides; Asparagine; beta 2-Microglobulin; Calmodulin; Glutamine; Hydrogen Bonding; Protein Folding; Protein Processing, Post-Translational; Protein Unfolding; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry | 2015 |
UV resonance Raman investigation of the aqueous solvation dependence of primary amide vibrations.
Topics: Amides; Asparagine; Glutamine; Hydrogen Bonding; Quantum Theory; Spectrum Analysis, Raman; Vibration; Water | 2015 |
Pulsed electromembrane extraction for analysis of derivatized amino acids: A powerful technique for determination of animal source of gelatin samples.
Topics: Animals; Asparagine; Cattle; Chromatography, High Pressure Liquid; Gelatin; Glutamine; o-Phthalaldehyde; Swine | 2015 |
Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma.
Topics: Asparagine; Cell Growth Processes; Glutamic Acid; Glutamine; Humans; Melanoma | 2015 |
Synthesis of 'head-to-tail' cyclized peptides on solid support using a chelating amide as new orthogonal protecting group.
Topics: Amides; Asparagine; Chelating Agents; Chemistry Techniques, Synthetic; Glutamine; Organometallic Compounds; Peptides, Cyclic; Pyridines; Solid-Phase Synthesis Techniques; Trimethylsilyl Compounds | 2015 |
Application of a portable infrared instrument for simultaneous analysis of sugars, asparagine and glutamine levels in raw potato tubers.
Topics: Amino Acids; Asparagine; Carbohydrates; Chromatography, High Pressure Liquid; Glutamine; Linear Models; Plant Tubers; Solanum tuberosum; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared | 2015 |
Preserved Proteins from Extinct Bison latifrons Identified by Tandem Mass Spectrometry; Hydroxylysine Glycosides are a Common Feature of Ancient Collagen.
Topics: Amino Acid Sequence; Animals; Asparagine; Bison; Collagen; Extinction, Biological; Glutamine; Glycosylation; Hydroxylysine; Molecular Sequence Data; Skull; Tandem Mass Spectrometry; Time Factors | 2015 |
PrionW: a server to identify proteins containing glutamine/asparagine rich prion-like domains and their amyloid cores.
Topics: Amyloid; Asparagine; Fungal Proteins; Glutamine; Internet; Prions; Protein Structure, Tertiary; Proteomics; Sequence Analysis, Protein; Software | 2015 |
Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase.
Topics: Asparaginase; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Glutamine; Models, Molecular; Molecular Dynamics Simulation | 2015 |
Deamidation of Human γS-Crystallin Increases Attractive Protein Interactions: Implications for Cataract.
Topics: Asparagine; Cataract; gamma-Crystallins; Glutamine; Humans; Models, Chemical; Protein Structure, Secondary; Protein Structure, Tertiary | 2015 |
Asparagine Repeat Peptides: Aggregation Kinetics and Comparison with Glutamine Repeats.
Topics: Asparagine; Glutamine; Peptides; Protein Structure, Secondary; Repetitive Sequences, Amino Acid | 2015 |
Role of host cell-derived amino acids in nutrition of intracellular Salmonella enterica.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Bacterial Proteins; Gene Expression Regulation, Bacterial; Glutamine; Glycoproteins; HeLa Cells; Host-Pathogen Interactions; Humans; Mice; Proline; Salmonella enterica; Succinate Dehydrogenase; Succinic Acid; Vacuoles | 2015 |
Glutamine and Asparagine Side Chain Hyperconjugation-Induced Structurally Sensitive Vibrations.
Topics: Asparagine; Deuterium Oxide; Glutamine; Molecular Structure; Spectrum Analysis, Raman; Water | 2015 |
Controlling the prion propensity of glutamine/asparagine-rich proteins.
Topics: Amyloid; Asparagine; Glutamine; Prions; Saccharomyces cerevisiae | 2015 |
General N-and O-Linked Glycosylation of Lipoproteins in Mycoplasmas and Role of Exogenous Oligosaccharide.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Cell Membrane; Cell Wall; Chromatography, Gas; Chromatography, Liquid; Disaccharides; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycoproteins; Glycosylation; Gram-Positive Bacteria; Hexoses; Lipoproteins; Mass Spectrometry; Molecular Sequence Data; Mycoplasma pneumoniae; Mycoplasma pulmonis; Oligosaccharides; Phylogeny; Protein Binding; Tandem Mass Spectrometry | 2015 |
Stable isotope studies reveal pathways for the incorporation of non-essential amino acids in Acyrthosiphon pisum (pea aphids).
Topics: Amino Acids; Animals; Aphids; Asparagine; Aspartic Acid; Buchnera; Carbon Isotopes; Glutamic Acid; Glutamine; Nitrogen; Nitrogen Isotopes; Symbiosis | 2015 |
Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1.
Topics: Amino Acid Substitution; Asparagine; Carboxylic Ester Hydrolases; Catalytic Domain; Crystallography, X-Ray; Gene Expression; Glutamine; Glycosylation; HEK293 Cells; Humans; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship | 2015 |
Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity.
Topics: Ammonia; Animals; Asparagine; Aspartate-Ammonia Ligase; Female; Glutamine; Humans; Leishmania infantum; Leishmaniasis, Visceral; Mice, Inbred BALB C; Molecular Sequence Data; Protozoan Proteins; Sequence Alignment; Virulence | 2016 |
Deamidation reactions of protonated asparagine and glutamine investigated by ion spectroscopy.
Topics: Asparagine; Glutamine; Molecular Structure; Protons; Spectrophotometry, Infrared | 2016 |
Amyloid Properties of Asparagine and Glutamine in Prion-like Proteins.
Topics: Amyloidogenic Proteins; Asparagine; Glutamine; GPI-Linked Proteins; Molecular Dynamics Simulation; Prion Proteins; Prions | 2016 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Topics: Arginine; Asparagine; Aspartate-Ammonia Ligase; Biological Transport; Cell Line, Tumor; Cell Proliferation; Culture Media; Gene Expression Regulation, Neoplastic; Glutamine; HeLa Cells; Histidine; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolic Networks and Pathways; Multiprotein Complexes; Nucleotides; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.
Topics: Asparagine; Carrier Proteins; Endosomes; Glutamine; HeLa Cells; Humans; Membrane Lipids; Microtubules; Peptides; Protein Binding; Protein Structure, Tertiary; Vesicular Transport Proteins | 2016 |
A Glutamine/Asparagine-Rich Fragment of Gln3, but not the Full-Length Protein, Aggregates in Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Cell Nucleus; Glutamine; Luminescent Proteins; Peptide Termination Factors; Prions; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 2016 |
Using Surface Scans for the Evaluation of Halogen Bonds toward the Side Chains of Aspartate, Asparagine, Glutamate, and Glutamine.
Topics: Amides; Amino Acids; Asparagine; Aspartic Acid; Carboxylic Acids; Crystallography, X-Ray; Drug Design; Glutamic Acid; Glutamine; Halogens; Models, Molecular; Molecular Conformation; Solvents | 2016 |
Characterization of Glutamine Deamidation by Long-Length Electrostatic Repulsion-Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry (LERLIC-MS/MS) in Shotgun Proteomics.
Topics: Asparagine; Brain Chemistry; Chromatography, Ion Exchange; Glutamine; Humans; Hydrophobic and Hydrophilic Interactions; Isomerism; Protein Processing, Post-Translational; Proteome; Proteomics; Tandem Mass Spectrometry | 2016 |
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping.
Topics: Amides; Amyloid; Animals; Asparagine; Aspartic Acid; Cattle; Enzyme Stability; Glutamine; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Domains; Protein Multimerization; Ribonuclease, Pancreatic | 2017 |
Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Topics: Amidohydrolases; Amino Acid Sequence; Asparagine; Catalytic Domain; Crystallography, X-Ray; Glutamine; Hydrogen Bonding; Kinetics; Models, Molecular; Peptides; Protein Conformation; Proteolysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 2016 |
Glycosylation affects the stability and subcellular distribution of human PAT1 protein.
Topics: Amino Acid Transport Systems; Asparagine; Blotting, Western; Cell Membrane; Endoplasmic Reticulum-Associated Degradation; Glutamine; Glycosylation; Green Fluorescent Proteins; HEK293 Cells; Humans; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Mutation, Missense; Protein Stability; Symporters; TOR Serine-Threonine Kinases | 2017 |
The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Topics: Amino Acid Sequence; Amino Acids; Asparaginase; Asparagine; Conserved Sequence; Enzyme Activation; Glutaminase; Glutamine; Kinetics; Models, Molecular; Point Mutation; Protein Conformation; Substrate Specificity; Wolinella | 2017 |
Minimizing Laboratory-Induced Decay in Bone Proteomics.
Topics: Acetates; Animals; Asparagine; Bone and Bones; Cattle; Edetic Acid; Forensic Medicine; Formates; Glutamine; Guanidine; Humans; Liquid-Liquid Extraction; Paleontology; Proteins; Proteolysis; Proteomics; Time Factors | 2017 |
Stereospecific assignment of the asparagine and glutamine sidechain amide protons in proteins from chemical shift analysis.
Topics: Algorithms; Amides; Asparagine; Glutamine; Magnetic Resonance Spectroscopy; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons; Software | 2017 |
Amino acid composition predicts prion activity.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Computational Biology; Glutamine; Humans; Machine Learning; Prions; Yeasts | 2017 |
Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer.
Topics: Asparagine; Autophagy; Cell Line, Tumor; Colonic Neoplasms; Glutamine; HEK293 Cells; Humans; Signal Transduction; Sulfides; Thiadiazoles | 2017 |
LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics.
Topics: Amides; Asparagine; Chromatography, Liquid; Glutamine; Humans; Hydrophobic and Hydrophilic Interactions; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry | 2017 |
Deamidation Slows Curli Amyloid-Protein Aggregation.
Topics: Amyloid beta-Peptides; Asparagine; Biofilms; Chromatography, High Pressure Liquid; Circular Dichroism; Deuterium Exchange Measurement; Escherichia coli; Escherichia coli Proteins; Glutamine; Kinetics; Models, Molecular; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Conformation, beta-Strand; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2017 |
Role of glutamine and interlinked asparagine metabolism in vessel formation.
Topics: Asparagine; Cell Movement; Cell Proliferation; Culture Media; Endothelial Cells; Glutaminase; Glutamine; Human Umbilical Vein Endothelial Cells; Humans; Metabolic Networks and Pathways; Neovascularization, Pathologic; Neovascularization, Physiologic | 2017 |
N-linked glycosylation of a subunit isoforms is critical for vertebrate vacuolar H
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Endoplasmic Reticulum; Glutamine; Glycosylation; HEK293 Cells; Humans; Mutation; Protein Binding; Protein Biosynthesis; Protein Stability; Protein Subunits; Vacuolar Proton-Translocating ATPases | 2018 |
The effects of glutamine/asparagine content on aggregation and heterologous prion induction by yeast prion-like domains.
Topics: Amyloid; Asparagine; Glutamine; Prions; Protein Aggregation, Pathological; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2017 |
Computational analysis of Asp519 and Glu665 mutations of coagulation factor FVIIIa: Implications for enhanced binding affinity of A2-domain.
Topics: Asparagine; Factor VIIIa; Glutamine; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Quantitative Structure-Activity Relationship | 2017 |
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides | 2017 |
ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma.
Topics: Activating Transcription Factor 4; Animals; Asparagine; Cancer-Associated Fibroblasts; Carcinogenesis; Cell Line, Tumor; Glucose; Glutamine; HEK293 Cells; Humans; Male; Mice; Prostatic Neoplasms; RNA-Binding Proteins; Stress, Physiological; Stromal Cells; Tumor Microenvironment; Ubiquitination | 2017 |
Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Asparagine; Aspartate-Ammonia Ligase; Binding Sites; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Child; Child, Preschool; Consanguinity; DNA Mutational Analysis; Female; Fibroblasts; Glutamine; Homozygote; Humans; Intellectual Disability; Male; Models, Molecular; Mutation; Seizures; Siblings | 2018 |
Effect of amino acids and frequency of reuse frying oils at different temperature on acrylamide formation in palm olein and soy bean oils via modeling system.
Topics: Acrylamide; Amino Acids; Asparagine; Cooking; Glutamine; Palm Oil; Soybean Oil; Temperature | 2018 |
Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.
Topics: Animals; Asparagine; DNA-Binding Proteins; Glutamine; HEK293 Cells; HSP40 Heat-Shock Proteins; Humans; Neurodegenerative Diseases; Neurons; Peptides; Prions; Protein Aggregates; RNA-Binding Protein FUS; Ubiquitin; Yeasts | 2018 |
As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.
Topics: Amino Acids, Essential; Animals; Asparaginase; Asparagine; Cell Line; Cell Line, Tumor; Cell Proliferation; Extracellular Space; Female; Glutamine; Humans; Mammals; Mice, Inbred C57BL; Protein Biosynthesis; Substrate Specificity | 2018 |
Novel mutant of Escherichia coli asparaginase II to reduction of the glutaminase activity in treatment of acute lymphocytic leukemia by molecular dynamics simulations and QM-MM studies.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Catalytic Domain; Drug Design; Escherichia coli Proteins; Glutamine; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation, Missense; Point Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Protein Conformation; Quantum Theory; Substrate Specificity; Thermodynamics | 2018 |
Quantifying Interactions of Nucleobase Atoms with Model Compounds for the Peptide Backbone and Glutamine and Asparagine Side Chains in Water.
Topics: Asparagine; Glutamine; Methylurea Compounds; Peptides; Thermodynamics; Urea; Water | 2018 |
The complex allosteric and redox regulation of the fumarate hydratase and malate dehydratase reactions of Arabidopsis thaliana Fumarase 1 and 2 gives clues for understanding the massive accumulation of fumarate.
Topics: Allosteric Regulation; Arabidopsis; Arabidopsis Proteins; Asparagine; Binding Sites; Evolution, Molecular; Fumarate Hydratase; Fumarates; Gene Expression; Gene Expression Regulation, Plant; Glutamine; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Models, Molecular; NADP; Oxaloacetic Acid; Oxidation-Reduction; Phylogeny; Protein Aggregates; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Recombinant Proteins; Substrate Specificity | 2018 |
Effects of nitrogen combined with zinc application on glutamate, glutamine, aspartate and asparagine accumulation in two winter wheat cultivars.
Topics: Asparagine; Aspartic Acid; Glutamic Acid; Glutamine; Nitrogen; Triticum; Zinc | 2018 |
Asparagine and Glutamine: Co-conspirators Fueling Metastasis.
Topics: Asparagine; Biological Availability; Breast Neoplasms; Glutamine; Humans; Metabolic Networks and Pathways | 2018 |
Sequence features governing aggregation or degradation of prion-like proteins.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Neurodegenerative Diseases; Peptide Termination Factors; Prions; Protein Aggregation, Pathological; Protein Domains; Proteolysis; Saccharomyces cerevisiae Proteins | 2018 |
ADPr-Peptide Synthesis.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Amino Acids; Asparagine; Fluorenes; Glutamine; Peptide Biosynthesis; Phosphorylation; Solid-Phase Synthesis Techniques | 2018 |
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutamine; Glutathione; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Metabolome; Methionine; Nitrogen; Streptococcus thermophilus | 2018 |
Coordination to Divalent Cations by Calcium-Binding Proteins.
Topics: Apoproteins; Asparagine; Calcium-Binding Proteins; Cations, Divalent; Glutamine; Models, Molecular; Spectroscopy, Fourier Transform Infrared; Water | 2019 |
Expression, purification, and characterization of asparaginase II from Saccharomyces cerevisiae in Escherichia coli.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Bacterial Proteins; Cell Line, Tumor; Cloning, Molecular; Escherichia coli; Gene Expression; Glutamine; Humans; Molecular Weight; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Saccharomyces cerevisiae | 2019 |
Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S-transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis.
Topics: Aged; Asparagine; Aspartic Acid; Cell Survival; Disease-Free Survival; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Glutathione Transferase; Humans; Lysine; Melanoma; Middle Aged; Prognosis; Proportional Hazards Models; Skin Neoplasms; Treatment Outcome; Xeroderma Pigmentosum | 2019 |
In-solution behavior and protective potential of asparagine synthetase A from Trypanosoma cruzi.
Topics: Ammonia; Animals; Asparagine; Aspartate-Ammonia Ligase; Chagas Disease; Chromatography, Liquid; Circular Dichroism; Disease Models, Animal; Dynamic Light Scattering; Glutamine; Mice, Inbred BALB C; Parasitemia; Protein Conformation; Protein Folding; Protozoan Vaccines; Recombinant Proteins; Trypanosoma cruzi; Vaccines, Synthetic | 2019 |
Asparagine Is a Critical Limiting Metabolite for Vaccinia Virus Protein Synthesis during Glutamine Deprivation.
Topics: Animals; Antiviral Agents; Asparagine; Cell Line; Glutamine; Humans; Metabolome; Poxviridae; Protein Biosynthesis; Vaccinia; Vaccinia virus; Viral Proteins; Virus Replication | 2019 |
Functional Research on Three Presumed Asparagine Synthetase Family Members in Poplar.
Topics: Asparagine; Aspartate-Ammonia Ligase; Escherichia coli; Gene Expression Regulation, Plant; Glutamate-Ammonia Ligase; Glutamine; Nitrogen; Populus | 2019 |
Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells.
Topics: Animals; Asparagine; Cell Line, Tumor; Cytoplasmic Granules; Cytoskeleton; DNA-Binding Proteins; Gene Ontology; Glutamine; Mice; Peptide Termination Factors; Prions; Protein Domains; Proteolysis; RNA-Binding Proteins; Saccharomyces cerevisiae Proteins | 2019 |
Alteration in NMDAR-related amino acids in first episode psychosis.
Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Effect of Single Amino Acid Substitutions by Asn and Gln on Aggregation Properties of Bence-Jones Protein BIF.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bence Jones Protein; Glutamine; Humans; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Protein Aggregates; Protein Conformation; X-Ray Diffraction | 2019 |
Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity.
Topics: Asparagine; Cell Line, Tumor; Glutamic Acid; Glutaminase; Glutamine; Glutathione; HEK293 Cells; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Proline | 2020 |
Effects of cysteine, asparagine, or glutamine limitations in Chinese hamster ovary cell batch and fed-batch cultures.
Topics: Animals; Antibody Formation; Asparagine; Batch Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Cysteine; Glutamine; Glycosylation; Humans; Immunoglobulin G | 2020 |
Assessment method for deamidation in proteins using carboxylic acid derivatization-liquid chromatography-tandem mass spectrometry.
Topics: Amides; Asparagine; Carboxylic Acids; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Storage; Glutamine; Peptide Fragments; Proteolysis; Serum Albumin, Bovine; Tandem Mass Spectrometry | 2020 |
Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 1; Amino Acids; Animals; Asparagine; Cell Cycle Proteins; Cell Line; Culture Media; Glutamine; HEK293 Cells; Humans; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Mice; Monomeric GTP-Binding Proteins; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus | 2020 |
Characterization of a novel type I l-asparaginase from Acinetobacter soli and its ability to inhibit acrylamide formation in potato chips.
Topics: Acinetobacter; Acrylamide; Asparaginase; Asparagine; Enzyme Stability; Escherichia coli; Glutamine; Snacks; Solanum tuberosum | 2020 |
Short disordered protein segment regulates cross-species transmission of a yeast prion.
Topics: Amino Acid Sequence; Asparagine; Cloning, Molecular; Escherichia coli; Gene Expression; Genetic Vectors; Glutamine; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Peptide Termination Factors; Prions; Protein Interaction Domains and Motifs; Protein Isoforms; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thermodynamics | 2020 |
Metabolomics approach revealed robust changes in amino acid and biogenic amine signatures in patients with schizophrenia in the early course of the disease.
Topics: Adult; Amino Acids; Antipsychotic Agents; Asparagine; Aspartic Acid; Biogenic Amines; Chromatography, Liquid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Metabolomics; Proline; Schizophrenia; Tandem Mass Spectrometry; Taurine; Young Adult | 2020 |
Demystifying the catalytic pathway of Mycobacterium tuberculosis isocitrate lyase.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Glutamine; Isocitrate Lyase; Isocitrates; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Conformation; Quantum Theory | 2020 |
Characterization of Penicillium crustosum L-asparaginase and its acrylamide alleviation efficiency in roasted coffee beans at non-cytotoxic levels.
Topics: Acrylamide; Asparaginase; Asparagine; Coffea; Electrophoresis, Polyacrylamide Gel; Glutamine; Molecular Weight; Penicillium; Seeds; Soil Microbiology; Substrate Specificity | 2021 |
Asparagine sustains cellular proliferation and c‑Myc expression in glutamine‑starved cancer cells.
Topics: Asparagine; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Gene Expression Regulation, Neoplastic; Glutamate-Ammonia Ligase; Glutamine; Humans; Leupeptins; Methionine Sulfoximine; Proteasome Endopeptidase Complex; Protein Isoforms; Proteolysis; Proto-Oncogene Proteins c-myc | 2021 |
Gut bacterial gene changes following pegaspargase treatment in pediatric patients with acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Genes, Bacterial; Glutamic Acid; Glutamine; Humans; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2021 |
SLC1A5 provides glutamine and asparagine necessary for bone development in mice.
Topics: Amino Acid Transport System ASC; Animals; Asparagine; Bone Development; Female; Glutamine; Mice; Minor Histocompatibility Antigens; Osteoblasts; Osteogenesis | 2021 |
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Topics: Apoptosis; Asparagine; Glutaminase; Glutamine; Humans; Reactive Oxygen Species | 2022 |
SNAT7 regulates mTORC1 via macropinocytosis.
Topics: Amino Acid Transport Systems, Neutral; Asparagine; Glutamine; Humans; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Pancreatic Neoplasms; Pinocytosis; Signal Transduction | 2022 |
Asparagine and Glutamine Residues Participate in Protein Covalent Binding by Epoxide Metabolite of 8-Epidiosbulbin E Acetate
Topics: Amides; Amines; Animals; Asparagine; Cytochrome P-450 CYP3A; Diterpenes; Epoxy Compounds; Glutamine; Lysine; Mice | 2022 |
Depletion of d- and l-asparagine in cerebrospinal fluid in acute lymphoblastic leukemia during PEGasparaginase therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Child; Child, Preschool; Glutamine; Humans; Infant; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease.
Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine | 2022 |
Glutamine synthetase plays an important role in ammonium tolerance of Myriophyllum aquaticum.
Topics: Ammonium Compounds; Animals; Asparagine; Glutamate-Ammonia Ligase; Glutamine; Methionine Sulfoximine; Nitrogen; Saxifragales; Swine; Wastewater | 2022 |
Aliivibrio fischeri L-Asparaginase production by engineered Bacillus subtilis: a potential new biopharmaceutical.
Topics: Aliivibrio fischeri; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus subtilis; Biological Products; Glutaminase; Glutamine; Pharmaceutical Preparations; Xylose | 2022 |
Unveiling the Essential Role of Arkadia's Non-RING Elements in the Ubiquitination Process.
Topics: Alanine; Arginine; Asparagine; Glutamine; Glycine; Isoleucine; Threonine; Transforming Growth Factor beta; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
Effects of multi-walled carbon nanotubes in soil on earthworm growth and reproduction, enzymatic activities, and metabolomics.
Topics: Animals; Asparagine; Aspartic Acid; Galactose; Glutamine; Glutathione Transferase; Nanotubes, Carbon; Oligochaeta; Oxidative Stress; Pyruvates; Reproduction; Soil; Soil Pollutants; Superoxide Dismutase | 2022 |
The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron.
Topics: Amino Acid Motifs; Asparagine; Cyclization; Dipeptides; Glutamine; Humans; Imides; Lenalidomide; Ligands; Peptide Hydrolases; Proteolysis; Proteome; Thalidomide; Ubiquitin-Protein Ligase Complexes; Ubiquitination | 2022 |
An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma.
Topics: Asparagine; Aspartate Aminotransferases; Biomarkers, Tumor; Carcinoma, Hepatocellular; Gene Expression Profiling; Glutamine; Humans; Liver Neoplasms; Prognosis; Tumor Microenvironment | 2022 |
Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells.
Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Spheroids, Cellular; Xenograft Model Antitumor Assays | 2022 |
Study the interaction of amino acids, sugars, thermal treatment and cooking technique on the formation of acrylamide in potato models.
Topics: Acrylamide; Amino Acids; Asparagine; Cooking; Fructose; Glucose; Glutamine; Hot Temperature; Solanum tuberosum; Sucrose; Sugars | 2023 |
Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53
Topics: Asparaginase; Asparagine; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Glutamine; Humans; Radiation, Ionizing; Tumor Suppressor Protein p53 | 2023 |
Metabolic factors associated with incident fracture among older adults with type 2 diabetes mellitus: a nested case-control study.
Topics: Aged; Amino Acids; Asparagine; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Fatty Acids; Fractures, Bone; Glutamine; Humans; Middle Aged; Risk Factors | 2023 |
Lipid Peroxidation Products Influence Calpain-1 Functionality In Vitro by Covalent Binding.
Topics: Aldehydes; Asparagine; Calpain; Chromatography, Liquid; Glutamine; Hexobarbital; Histidine; Lipid Peroxidation; Lysine; Tandem Mass Spectrometry | 2023 |
Targeted Amino Acids Profiling of Human Seminal Plasma from Teratozoospermia Patients Using LC-MS/MS.
Topics: Amino Acids; Asparagine; Biomarkers; Case-Control Studies; Chromatography, Liquid; Cysteine; Glutamine; Glycine; Humans; Male; Semen; Tandem Mass Spectrometry; Teratozoospermia; Tryptophan; Valine | 2023 |
Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement.
Topics: Amino Acids; Animals; Artemisinins; Asparagine; Glutamate-Ammonia Ligase; Glutamine; Humans; Parasites; Plasmodium falciparum | 2023 |
Study on the non-enzymatic browning of lotus rhizome juice during sterilization mediated by 1,2-dicarboxyl and heterocyclic compounds.
Topics: Asparagine; Fructose; Glucose; Glutamine; Glyoxal; Heterocyclic Compounds; Lotus; Lysine; Maillard Reaction; Pyruvaldehyde; Rhizome; Sterilization | 2024 |
Development of a bioengineered Erwinia chrysanthemi asparaginase to enhance its anti-solid tumor potential for treating gastric cancer.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Dickeya chrysanthemi; Enterobacteriaceae; Glutamine; Humans; Mice; Serum Albumin; Stomach Neoplasms | 2023 |