asparagine and glutaminase

asparagine has been researched along with glutaminase in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (59.38)	18.7374
1990's	3 (4.69)	18.2507
2000's	5 (7.81)	29.6817
2010's	9 (14.06)	24.3611
2020's	9 (14.06)	2.80

Authors

Authors	Studies
Banks, GT; Bascomb, S; Bettelheim, KA; Fleming, A; Skarstedt, MT	1
Cooney, DA; Homan, ER; Jayaram, HN; Milman, HA; Rosenbluth, RJ	1
Badr El-Din, SM; Foda, MS	1
Abuchowski, A; Davis, FF; McCoy, JR; Palczuk, NC; van Es, T	1
Rabinovitz, M; Rabon, A; Vistica, DT	1
Spiers, AS; Wade, HE	1
Dolowy, WC; Holcenberg, JS; Tang, E	1
Salloum, RM; Souba, WW; Stevens, BR	1
Bowen, DM; Esiri, MM; Francis, PT; Hunt, A; Lowe, SL; Najlerahim, A; Palmer, AM; Patel, AJ; Procter, AW; Stratmann, GC	1
Bergenstal, R; Burg, A; Cooney, DA; Fleischman, R; Morrison, R; Yavelow, J; Zlotoff, R	1
Nahorski, SR	1
Anderson, PM; Meister, A; Wellner, VP	1
Novak, EK; Phillips, AW	1
Oshima, M; Soda, K; Yamamoto, T	1
Berezov, TT; Hisamov, GZ; Zanin, VA	1
Laki, K; Wilson, E	1
Berezov, TT; Evseev, LP; Khisamov, GZ; Zanin, VA	1
Dolowy, WC; Fitzmaurice, MA; Holcenberg, JS; Riley, V; Roberts, J; Spackman, D	1
Goodman, D; Kafkewitz, D	1
Balis, ME; Miller, HK	1
Laboureur, P	1
Dolowy, WC; Holcenberg, JS; Roberts, J	1
Jacobasch, KH	1
Milner, L; Prusiner, S	1
Hayashida, H; Kikuchi, M; Nakano, E; Sakaguchi, K	1
Gross, R; Hirschmann, WD; Oerkermann, H	1
Boyse, EA; Campbell, HA; Mashburn, LT; Old, LJ	1
Sergeeva, SA	1
Tower, DB; Wherrett, JR	1
Foda, MS; Hashem, SA; Zedan, HH	1
Balling, R; Coon, C	1
Bendich, A; Kafkewitz, D	2
Abuchowski, A; Bendich, A; Davis, FF; Kafkewitz, D	1
Herbert, RA; Macfarlane, GT	1
Holcenberg, JS	1
Rennie, MJ; Tadros, LB; Taylor, PM; Willhoft, NM	1
Greenman, J; Hassan, IJ; Millar, MR; Stark, RM; Suleiman, MS	1
Dorr, RT; Fanta, P; Hersh, EM; Salmon, SE; Taylor, CW	1
GREENBERG, DM; RAMADAN, ME	1
EHRENFELD, E; MARBLE, SJ; MEISTER, A	1
TURSKY, T; VALOVICOVA, E	1
Hövel, S; Klöppner, U; Röhm, KH; Sonawane, A; Völker, U	1
Bootim, N; Kamemura, A; Moriguchi, M; Tachiki, T; Wakayama, M; Yamagata, T; Yano, S; Yoshimune, K	1
Chimnaronk, S; Nakamura, A; Sakai, N; Tanaka, I; Yao, M	1
Kumar, S; Pakshirajan, K; Venkata Dasu, V	1
Bussolati, O; Chiarelli, LR; Covini, D; Digilio, R; Pasquetto, MV; Scotti, C; Tardito, S; Valentini, G	1
Doble, M; Ln, R; Pulicherla, KK; Rekha, VP	1
Kango, N; Saxena, A; Upadhyay, R	1
De Zoysa, M; Heo, SJ; Jung, WK; Kang, DH; Kim, H; Lee, DW; Lee, SJ; Lee, Y; Oh, C; Park, GH; Umasuthan, N	1
Durden, DL; Lavie, A; Nguyen, HA	1
Bierhansl, L; Brepoels, K; Brüning, U; Carmeliet, P; Cruys, B; Cubbon, R; Dewerchin, M; Eelen, G; Ghesquière, B; Goveia, J; Huang, H; Kalucka, J; Rayport, S; Schoonjans, L; Vandekeere, S; Vinckier, S; Visnagri, A; Wyns, S; Yuldasheva, N; Zecchin, A	1
Eoh, H; Gao, SJ; Jung, JU; Lee, JJ; Li, T; Lu, C; Ramos da Silva, S; Zhu, Y	1
Akhtar, M; Chohan, SM; Coker, AR; Cooper, JB; Guo, J; Rashid, N; Wood, SP	1
Cai, Y; Cao, T; Chen, J; Du, F; Fan, D; Han, W; Liu, H; Nie, Y; Qian, M; Tian, D; Wu, K; Xia, L; Yi, X	1
Gerrits, J; Houwen, RHJ; Jans, JJM; Pras-Raves, ML; Rumping, L; Tang, YF; van Haaften, G; van Hasselt, PM; Verhoeven-Duif, NM; Willemsen, MA	1
Alcaro, S; Coricello, A; Radadiya, A; Richards, NGJ; Zhu, W	1
Chakraborty, M; Shivakumar, S	1
Manonmani, HK; Sindhu, R	1
Cao, Y; Chen, X; Han, A; Hu, J; Jiang, B; Li, Q; Lin, D; Lin, F; Liu, M; Liu, Q; Ma, H; Wang, J; Wu, C; Yao, L; Zhang, C; Zhang, J; Zhao, G; Zhao, W; Zheng, Y	1
Chan, WK; Chiche, J; Grima-Reyes, M; Lorenzi, PL; Marchetti, S; Martinez-Turtos, A; Meola, P; Nemazanyy, I; Nottet, N; Paul, R; Reverso-Meinietti, J; Ricci, JE; Vandenberghe, A	1
Almeida, MR; Bento, HBS; Carvalho, PJ; Paiva, GB; Pedrolli, DB; Santos-Ebinuma, VC; Silva, CG; Tavares, APM	1
Chan, WK; De Moerloose, B; De Visser, Y; Goossens, S; Lammens, T; Lavie, A; Lee, H; Lorenzi, PL; Mondelaers, V; Nguyen, HA; Peeters, E; Reunes, L; Schalk, AM; Su, Y; Van Trimpont, M; Van Vlierberghe, P; Vandemeulebroecke, K	1
Beitel, SM; Izidoro, SC; Knob, A; Lacerda, LT; Ratuchne, A	1

Reviews

6 review(s) available for asparagine and glutaminase

Article	Year
[Biochemistry of asparaginase. Properties of the asparaginase system and biological activity]. Pathologie-biologie, 1969, Volume: 17, Issue:19 Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Enzyme Repression; Glutaminase; Mice; Rabbits; Rats; Ribonucleases	1969
[Enzyme therapy of malignant tumors]. Archiv fur Geschwulstforschung, 1969, Volume: 34, Issue:4 Topics: Animals; Asparaginase; Asparagine; Glutaminase; Guinea Pigs; Humans; Leukemia; Mice; Neoplasms; Neoplasms, Experimental; Rabbits; Rats	1969
Enzyme-induced asparagine and glutamine depletion and immune system function. The American journal of clinical nutrition, 1983, Volume: 37, Issue:6 Topics: Ammonia; Animals; Asparaginase; Asparagine; Escherichia coli; Glutaminase; Glutamine; Humans; Immunosuppressive Agents; Leukemia; Lymphocytes; Polyethylene Glycols; Vibrio	1983
The inhibition of lymphocyte mitogenesis by asparaginase: a still unexplained phenomenon. Experientia, 1984, Nov-15, Volume: 40, Issue:11 Topics: Animals; Asparaginase; Asparagine; Cell Membrane; Cells, Cultured; Erwinia; Escherichia coli; Glutaminase; Glutamine; Glycoproteins; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Membrane Proteins; Mitosis; Models, Biological; Polyethylene Glycols; Vibrio	1984
Expanding targets for a metabolic therapy of cancer: L-asparaginase. Recent patents on anti-cancer drug discovery, 2012, Volume: 7, Issue:1 Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2012
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review. Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:13 Topics: Asparaginase; Asparagine; Child; Escherichia coli; Glutaminase; Glutamine; Humans; Leukemia	2022

Trials

2 trial(s) available for asparagine and glutaminase

Article	Year
Bacterial glutaminase in treatment of acute leukaemia. British medical journal, 1976, May-29, Volume: 1, Issue:6021 Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Asparagine; Child; Clinical Trials as Topic; Female; Glutaminase; Glutamine; Half-Life; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male	1976
A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors. Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:1 Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms	2001

Article

Year

Bacterial glutaminase in treatment of acute leukaemia.

British medical journal, 1976, May-29, Volume: 1, Issue:6021

Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Asparagine; Child; Clinical Trials as Topic; Female; Glutaminase; Glutamine; Half-Life; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male

1976

A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors.

Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:1

Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms

2001

Other Studies

56 other study(ies) available for asparagine and glutaminase

Article	Year
The properties and large-scale production of L-asparaginase from citrobacter. Journal of general microbiology, 1975, Volume: 91, Issue:1 Topics: Animals; Asparaginase; Asparagine; Citrobacter; Culture Media; Drug Evaluation, Preclinical; Enterobacteriaceae; Fermentation; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Lymphoma, Non-Hodgkin; Mice; Molecular Weight; Neoplasms, Experimental; Oxygen; Stereoisomerism; Temperature; Zea mays	1975
Don, conv and donv--I. Inhibition of L-asparagine synthetase in vitro. Biochemical pharmacology, 1976, Jul-15, Volume: 25, Issue:14 Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Azo Compounds; Diazooxonorleucine; Glutamate-Ammonia Ligase; Glutaminase; In Vitro Techniques; Ligases; Male; Mice; Mice, Inbred Strains; Pancreas; Time Factors; Transaminases	1976
Kinetics and properties of L-glutaminase and L-asparaginase activities of Pseudomonas ovalis. Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie, 1976, Volume: 131, Issue:3 Topics: Asparaginase; Asparagine; Enzyme Induction; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Pseudomonas; Streptomycin; Tetracyclines; Time Factors	1976
Treatment of L5178Y tumor-bearing BDF1 mice with a nonimmunogenic L-glutaminase-L-asparaginase. Cancer treatment reports, 1979, Volume: 63, Issue:6 Topics: Amidohydrolases; Animals; Antibody Formation; Asparaginase; Asparagine; Drug Therapy, Combination; Glutaminase; Glutamine; Metabolic Clearance Rate; Mice; Neoplasms, Experimental; Polyethylene Glycols	1979
Enhancement of melphalan therapy with glutaminase:asparaginase. Research communications in chemical pathology and pharmacology, 1978, Volume: 22, Issue:1 Topics: Acinetobacter; Animals; Asparaginase; Asparagine; Drug Synergism; Glutaminase; Glutamine; Leukemia L1210; Melphalan; Mice; Time Factors	1978
Effect of Acinetobacter glutaminase-asparaginase treatment on free amino acids in mouse tissues. Cancer research, 1975, Volume: 35, Issue:5 Topics: Acetyltransferases; Acinetobacter; Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Body Weight; Brain; Escherichia coli; Female; Glutamates; Glutaminase; Glutamine; Kidney; Mice; Organ Size; Serine; Spleen; Threonine	1975
Adaptive regulation of brush-border amino acid transport in a chronic excluded jejunal limb. The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 1 Topics: Alanine; Anastomosis, Roux-en-Y; Asparagine; Biological Transport, Active; Glucose; Glutaminase; Glutamine; Histidine; Jejunum; Kinetics; Microvilli; Sodium	1991
Topographical distribution of neurochemical changes in Alzheimer's disease. Journal of the neurological sciences, 1988, Volume: 84, Issue:2-3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids, Dicarboxylic; Asparagine; Aspartic Acid; Cerebellar Cortex; Cerebral Cortex; Choline O-Acetyltransferase; Glutamates; Glutaminase; Glutamine; Humans; Middle Aged; Somatostatin	1988
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice. Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24 Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia; Azo Compounds; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Diarrhea; DNA; Formates; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Lethal Dose 50; Ligases; Liver Neoplasms; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Protein Biosynthesis; Seizures; Spleen; Time Factors	1974
Fluorometric measurement of glutamine and asparagine using enzymic methods. Analytical biochemistry, 1971, Volume: 42, Issue:1 Topics: Adenine Nucleotides; Animals; Asparaginase; Asparagine; Aspartate Aminotransferases; Cerebral Cortex; Escherichia coli; Fluorometry; Glutamate Dehydrogenase; Glutaminase; Glutamine; Hydrolysis; Ketoglutaric Acids; Malate Dehydrogenase; Methods; NAD; Rats	1971
Interaction of Escherichia coli carbamyl phosphate synthetase with glutamine. Biochemistry, 1973, May-22, Volume: 12, Issue:11 Topics: Adenosine Triphosphate; Amides; Amino Acids; Asparagine; Bicarbonates; Binding Sites; Carbamates; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Glutaminase; Glutamine; Keto Acids; Kinetics; Magnesium; Molecular Weight; Phosphotransferases; Protein Binding; Protein Denaturation; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship	1973
L-glutamine as a substrate for L-asparaginase from Serratia marcescens. Journal of bacteriology, 1974, Volume: 117, Issue:2 Topics: Ammonium Sulfate; Animals; Asparaginase; Asparagine; Chemical Precipitation; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Escherichia coli; Female; Glutaminase; Glutamine; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Mice; Mice, Inbred C3H; Serratia marcescens; Spectrophotometry; Stereoisomerism	1974
Purification and properties of isozymes of glutaminase from Pseudomonas aeruginosa. Biochemical and biophysical research communications, 1972, Feb-16, Volume: 46, Issue:3 Topics: Amides; Ammonium Sulfate; Anilides; Asparagine; Catalysis; Chemical Precipitation; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Crystallization; Electrophoresis, Disc; Glutamates; Glutaminase; Hydrazines; Hydroxylamines; Isoenzymes; Kinetics; Mercury; Molecular Weight; Nitro Compounds; Pseudomonas aeruginosa; Stereoisomerism; Structure-Activity Relationship; Ultracentrifugation	1972
On the regulation of asparaginase synthesis in Pseudomonas Boreopolis 526. FEBS letters, 1972, Nov-15, Volume: 28, Issue:1 Topics: Asparaginase; Asparagine; Aspartic Acid; Enzyme Induction; Enzyme Repression; Glutaminase; Kinetics; Pseudomonas	1972
The action of hydroxylamine on myosin. Physiological chemistry and physics, 1972, Volume: 4, Issue:3 Topics: Amino Acids; Animals; Asparagine; Glutaminase; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxylamines; Myosins; Protein Binding; Protein Conformation; Rabbits	1972
[Characteristics of asparaginase and glutaminase synthesis in Ps. boreopolis 526]. Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:10 Topics: Asparaginase; Asparagine; Aspartic Acid; Glutamates; Glutaminase; Glutamine; Ligases; Pseudomonas	1973
Therapeutic properties of a new glutaminase-asparaginase preparation and the influence of the lactate dehydrogenase-elevating virus. Cancer research, 1974, Volume: 34, Issue:2 Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamates; Glutaminase; Glutamine; Half-Life; Hydrogen-Ion Concentration; Isoelectric Focusing; L-Lactate Dehydrogenase; Leukemia, Experimental; Mice; Mice, Inbred C57BL; RNA Viruses	1974
L-Asparaginase production by the rumen anaerobe Vibrio succinogenes. Applied microbiology, 1974, Volume: 27, Issue:1 Topics: Anaerobiosis; Animals; Asparaginase; Asparagine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Culture Media; Electron Transport; Fumarates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Malates; Nitrates; Rumen; Stereoisomerism; Succinates; Vibrio	1974
Glutaminase activity of L-asparagine amidohydrolase. Biochemical pharmacology, 1969, Volume: 18, Issue:9 Topics: Asparaginase; Asparagine; Azaserine; Carbon Isotopes; Escherichia coli; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine	1969
Antineoplastic activity of highly purified bacterial glutaminases. Nature, 1970, Sep-12, Volume: 227, Issue:5263 Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacteria; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Escherichia coli; Female; Glutaminase; Glutamine; Leucine; Mice; Neoplasm Proteins	1970
A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase. Analytical biochemistry, 1970, Volume: 37, Issue:2 Topics: Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Escherichia coli; Glutamates; Glutaminase; Glutamine; Ligases	1970
Peptidoglutaminase. Enzymes for selective deamidation of gamma-amide of peptide-bound glutamine. Biochemistry, 1971, Mar-30, Volume: 10, Issue:7 Topics: Amides; Amino Acids; Amino Alcohols; Asparagine; Bacillus; Carbon Isotopes; Caseins; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis; Escherichia coli; Glutaminase; Glutamine; Glycine; Hydroxamic Acids; Hydroxyapatites; Methods; Paper; Peptide Hydrolases; Peptides; Phenylalanine; Soil Microbiology	1971
Studies on the glutaminase activity of E. coli asparaginase in tissue culture. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33 Topics: Asparaginase; Asparagine; Carbon Isotopes; Depression, Chemical; Drug Resistance; Eosinophils; Escherichia coli; Glutamates; Glutaminase; Glutamine; HeLa Cells; Humans; Leucine; Leukocytes; Lymphocyte Activation; Mitosis; Monocytes; Neutrophils; Stimulation, Chemical; Thymidine; Uridine	1970
Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity. Biochemistry, 1967, Volume: 6, Issue:3 Topics: Amidohydrolases; Antineoplastic Agents; Asparagine; Chromatography; Escherichia coli; Glutaminase; Hydrogen-Ion Concentration; Lymphoma	1967
[Seasonal changes in the activity of enzymes, desaminizing glutamine in the brain of Spermophilus]. Ukrains'kyi biokhimichnyi zhurnal, 1969, Volume: 41, Issue:2 Topics: Ammonia; Animals; Asparagine; Brain; Glutaminase; Glutamine; Rodentia; Seasons; Transaminases	1969
Glutamyl, aspartyl and amide moieties of cerebral proteins: metabolic aspects in vitro. Journal of neurochemistry, 1971, Volume: 18, Issue:6 Topics: Amides; Ammonia; Ammonium Chloride; Animals; Asparaginase; Asparagine; Aspartic Acid; Autoradiography; Carbon Isotopes; Carboxy-Lyases; Cats; Cerebral Cortex; Glutamates; Glutaminase; Glutamine; Hydrolases; Hydrolysis; In Vitro Techniques; Mass Spectrometry; Nerve Tissue Proteins; Nitrogen Isotopes; Protein Binding	1971
Formation and properties of L-glutaminase and L-asparaginase activities in Pichia polymorpha. Acta microbiologica Polonica, 1980, Volume: 29, Issue:4 Topics: Ascomycota; Asparaginase; Asparagine; Cations, Divalent; Enzyme Induction; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Pichia; Substrate Specificity; Temperature	1980
Asparagine and glutamine metabolism in chicks. Poultry science, 1984, Volume: 63, Issue:4 Topics: Amino Acids; Ammonium Chloride; Animals; Asparaginase; Asparagine; Bicarbonates; Chickens; Dietary Proteins; Glutaminase; Glutamine; Kidney; Liver; Mitochondria; Mitochondria, Liver; Sodium Bicarbonate	1984
Inhibition of blastogenesis by native and polyethylene glycol-modified asparaginases from Escherichia coli and Vibrio succinogenes. Immunological communications, 1983, Volume: 12, Issue:3 Topics: Animals; Asparaginase; Asparagine; Cells, Cultured; Escherichia coli; Glutaminase; Glutamine; Immunosuppressive Agents; Lymphocyte Activation; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Vibrio	1983
Asparagine and glutamine metabolism in Rhodopseudomonas acidophila. Archives of microbiology, 1980, Volume: 128, Issue:2 Topics: Asparaginase; Asparagine; Glutaminase; Glutamine; Glycine; Glyoxylates; Methionine Sulfoximine; Rhodopseudomonas; Transaminases	1980
Enzyme therapy of cancer, future studies. Cancer treatment reports, 1981, Volume: 65 Suppl 4 Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice	1981
Effects of glutamine deprivation on glutamine transport and synthesis in primary culture of rat skeletal muscle. The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1 Topics: Amino Acids; Animals; Animals, Newborn; Asparagine; Biological Transport; Cell Differentiation; Cell Division; Cells, Cultured; Cycloheximide; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Histidine; Insulin; Kinetics; Methionine Sulfoximine; Muscles; Rats; Time Factors; Tritium	1993
Amino acid utilisation and deamination of glutamine and asparagine by Helicobacter pylori. Journal of medical microbiology, 1997, Volume: 46, Issue:9 Topics: Amino Acids; Ammonia; Asparaginase; Asparagine; Culture Media; Diazooxonorleucine; Enzyme Inhibitors; Glutaminase; Glutamine; Helicobacter pylori	1997
AN ENZYMIC MICROMETHOD FOR DETERMINATION OF GLUTAMINE AND ASPARAGINE IN BLOOD. Analytical biochemistry, 1963, Volume: 6 Topics: Amidohydrolases; Animals; Asparagine; Blood Chemical Analysis; Colorimetry; Glutaminase; Glutamine; Guinea Pigs; Microchemistry; Pseudomonas; Rabbits; Rats; Research	1963
ENZYMATIC SYNTHESIS OF GAMMA-GLUTAMYLHYDROXAMIC ACID FROM GLUTAMIC ACID AND HYDROXYLAMINE. The Journal of biological chemistry, 1963, Volume: 238 Topics: Amidohydrolases; Ammonia; Antimetabolites; Asparagine; Azaserine; Azotobacter; Carbon Isotopes; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Pharmacology; Proteins; Research; Streptomycin	1963
ASPARAGINASE IN THE BRAIN OF GUINEA PIG IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS. Journal of neurochemistry, 1964, Volume: 11 Topics: Amidohydrolases; Animals; Asparaginase; Asparagine; Benzoates; Brain; Cerebellum; Chromatography; Clinical Enzyme Tests; Encephalomyelitis; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Glutaminase; Guinea Pigs; Hydrogen-Ion Concentration; Hypersensitivity; Kidney; Liver; Medulla Oblongata; Organophosphate Poisoning; Phosphorus; Poisons; Pons; Research; Tissue Extracts; Zinc	1964
Identification of Pseudomonas proteins coordinately induced by acidic amino acids and their amides: a two-dimensional electrophoresis study. Microbiology (Reading, England), 2003, Volume: 149, Issue:Pt 10 Topics: Asparaginase; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Glutaminase; Glutamine; Periplasm; Proteomics; Pseudomonas fluorescens; Pseudomonas putida; Reverse Transcriptase Polymerase Chain Reaction; Sigma Factor	2003
Characterization of salt-tolerant glutaminase from Stenotrophomonas maltophilia NYW-81 and its application in Japanese soy sauce fermentation. Journal of industrial microbiology & biotechnology, 2005, Volume: 32, Issue:9 Topics: Amino Acid Sequence; Asparagine; Aspergillus oryzae; Chromatography, Gel; DNA, Bacterial; DNA, Ribosomal; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Fermentation; Glutamic Acid; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Micrococcus luteus; Molecular Sequence Data; Molecular Weight; Pseudomonas; Saline Solution, Hypertonic; Soy Foods; Stenotrophomonas maltophilia; Substrate Specificity; Temperature	2005
Ammonia channel couples glutaminase with transamidase reactions in GatCAB. Science (New York, N.Y.), 2006, Jun-30, Volume: 312, Issue:5782 Topics: Adenosine Diphosphate; Amino Acid Sequence; Aminoacyltransferases; Ammonia; Apoenzymes; Asparagine; Base Pairing; Catalytic Domain; Crystallography, X-Ray; Glutaminase; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Magnesium; Manganese; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; RNA, Bacterial; RNA, Transfer, Amino Acyl; RNA, Transfer, Gln; Staphylococcus aureus	2006
Development of medium for enhanced production of glutaminase-free L-asparaginase from Pectobacterium carotovorum MTCC 1428. Applied microbiology and biotechnology, 2009, Volume: 84, Issue:3 Topics: Antineoplastic Agents; Asparaginase; Asparagine; Biotechnology; Culture Media; Glucose; Glutaminase; Models, Statistical; Pectobacterium carotovorum	2009
In silico engineering of L-asparaginase to have reduced glutaminase side activity for effective treatment of acute lymphoblastic leukemia. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8 Topics: Asparaginase; Asparagine; Catalytic Domain; Child; Computer Simulation; Drug Design; Glutaminase; Glutamine; Humans; Ligands; Mutagenesis, Site-Directed; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Engineering	2011
Isolation and identification of actinomycetes for production of novel extracellular glutaminase free L-asparaginase. Indian journal of experimental biology, 2015, Volume: 53, Issue:12 Topics: Antineoplastic Agents; Asparaginase; Asparagine; Bacterial Proteins; Biocatalysis; Fermentation; Glutaminase; Hydrolysis; Industrial Microbiology; Soil Microbiology; Streptomyces	2015
A Newly Identified Glutaminase-Free ʟ-Asparaginase (ʟ-ASPG86) from the Marine Bacterium Mesoflavibacter zeaxanthinifaciens. Journal of microbiology and biotechnology, 2016, Jun-28, Volume: 26, Issue:6 Topics: Amino Acid Sequence; Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Flavobacteriaceae; Glutaminase; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Models, Molecular; Phylogeny; Recombinant Proteins; Seawater; Substrate Specificity; Yersinia pseudotuberculosis	2016
The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity. Scientific reports, 2017, 01-31, Volume: 7 Topics: Amino Acid Sequence; Amino Acids; Asparaginase; Asparagine; Conserved Sequence; Enzyme Activation; Glutaminase; Glutamine; Kinetics; Models, Molecular; Point Mutation; Protein Conformation; Substrate Specificity; Wolinella	2017
Role of glutamine and interlinked asparagine metabolism in vessel formation. The EMBO journal, 2017, 08-15, Volume: 36, Issue:16 Topics: Asparagine; Cell Movement; Cell Proliferation; Culture Media; Endothelial Cells; Glutaminase; Glutamine; Human Umbilical Vein Endothelial Cells; Humans; Metabolic Networks and Pathways; Neovascularization, Pathologic; Neovascularization, Physiologic	2017
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. mBio, 2017, 08-15, Volume: 8, Issue:4 Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides	2017
Structure and function of the thermostable L-asparaginase from Thermococcus kodakarensis. Acta crystallographica. Section D, Structural biology, 2017, Nov-01, Volume: 73, Issue:Pt 11 Topics: Amino Acid Sequence; Asparaginase; Asparagine; Catalytic Domain; Crystallization; Crystallography, X-Ray; Glutaminase; Hydrolysis; Models, Molecular; Protein Conformation; Sequence Homology; Thermococcus	2017
SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis. Cell death & disease, 2019, 03-11, Volume: 10, Issue:3 Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Biomarkers, Tumor; Caco-2 Cells; Cell Movement; Cell Proliferation; Cohort Studies; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutaminase; HCT116 Cells; HT29 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prognosis; SOXC Transcription Factors; Transaminases; Transplantation, Heterologous; Up-Regulation	2019
Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity. Biochimica et biophysica acta. General subjects, 2020, Volume: 1864, Issue:3 Topics: Asparagine; Cell Line, Tumor; Glutamic Acid; Glutaminase; Glutamine; Glutathione; HEK293 Cells; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Proline	2020
Improving the Treatment of Acute Lymphoblastic Leukemia. Biochemistry, 2020, 09-08, Volume: 59, Issue:35 Topics: Adolescent; Asparaginase; Asparagine; Child; Child, Preschool; Glutaminase; Humans; Medical Oncology; Models, Molecular; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Conformation; Quality Improvement; Young Adult	2020
Bioprospecting of the agaricomycete Ganoderma australe GPC191 as novel source for L-asparaginase production. Scientific reports, 2021, 03-18, Volume: 11, Issue:1 Topics: Antineoplastic Agents; Asparaginase; Asparagine; Enzyme Assays; Fruiting Bodies, Fungal; Fungal Proteins; Ganoderma; Gene Expression; Glutaminase; Humans; Kinetics; Phylogeny; Urease	2021
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis. Molecular cell, 2022, 05-19, Volume: 82, Issue:10 Topics: Apoptosis; Asparagine; Glutaminase; Glutamine; Humans; Reactive Oxygen Species	2022
Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression. Science advances, 2022, 07-08, Volume: 8, Issue:27 Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Cell Line, Tumor; Glutaminase; Lymphoma, B-Cell; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Microenvironment	2022
Aliivibrio fischeri L-Asparaginase production by engineered Bacillus subtilis: a potential new biopharmaceutical. Bioprocess and biosystems engineering, 2022, Volume: 45, Issue:10 Topics: Aliivibrio fischeri; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus subtilis; Biological Products; Glutaminase; Glutamine; Pharmaceutical Preparations; Xylose	2022
Haematologica, 2023, 02-01, Volume: 108, Issue:2 Topics: Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutaminase; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2023
A new extracellular glutaminase and urease-free L-asparaginase from Meyerozyma guilliermondii. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023, Volume: 54, Issue:2 Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Glucose; Glutaminase; Urease	2023