asparagine and epidermal growth factor

asparagine has been researched along with epidermal growth factor in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19908 (24.24)18.7374
1990's16 (48.48)18.2507
2000's6 (18.18)29.6817
2010's2 (6.06)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Hoshi, K; Kasai, H; Kohri, K; Koide, H; Miyake, T; Muto, Y; Sasaki, T; Takahashi, S; Takusari, H; Tsukumo, K1
Stenflo, J1
Arlaud, GJ; Aude, C; Bell, A; Gagnon, J; Mancini, M; Van Dorsselaer, A1
Bennett, CD; Friedman, PA; Musson, DG; Przysiecki, CT; Ramjit, HG; Staggers, JE; Stern, AM1
Ohlin, AK; Owen, WG; Schneider, WJ; Stenflo, J1
Canellakis, ES; Fong, WF; Ortiz, JG; Rinehart, CA; Viceps-Madore, D1
Dahlbäck, B; Lundwall, A; Stenflo, J1
DiAugustine, RP; Grove, RI; Harvan, DJ; Hernandez, O; Klapper, DG; Walker, MP; Willis, WD1
Aberth, W; Brown, CF; DiAugustine, RP; Ferrua, CM; Gibson, BW; Kelly, M; Tomooka, Y; Walker, M1
Canellakis, ES; Rinehart, CA1
Brown, KN; McKean, PG; O'Dea, K1
Johnson, LR; McCormack, SA; Viar, MJ; Wang, JY1
Burgeson, RE; Gerecke, DR; Mayer, U; Pöschl, E; Timpl, R; Wagman, DW1
Arrandale, JM; Dannies, PS1
Iwanaga, S; Miyata, T; Niho, Y; Nishimura, H; Okamura, T; Suehiro, K; Takeya, H1
Biamonti, C; Campion, SR; Montelione, GT; Niyogi, SK1
Worley, PF; Yee, WM1
Dickinson, CD; Kelly, CR; Ruf, W1
Boyd, J; Campbell, ID; Mal, TK; Soffe, N1
Drakenberg, T; Finn, BE; Forsén, S; Gippert, GP; Muranyi, A; Stenflo, J1
Bass, BL; Li, J; Li, L; Patel, AR; Summers, S; Wang, JY1
Nielsen, LS; Persson, E1
Johnson, LR; Patel, TB; Ray, RM; Viar, MJ1
Björk, I; Stenflo, J; Valcarce, C1
Chang, YJ; Hamaguchi, N; Hsu, YC; Lin, SW; Wu, HL1
Kaelin, WG1
Chang, YJ; Lin, SW; Walsh, PN; Yang, X1
Beth, AH; Johns, TG; McCoy, AJ; Red-Brewer, ML; Staros, JV; Vitali, AA; Walker, F; Whitson, KB; Whitson, SR1
Manithody, C; Rezaie, AR; Yang, L1
Carlson, CB; Keck, JL; Liu, Y; Mosher, DF1
Lins, RD; Lower, SK; Pol-Fachin, L; Taylor, ES1
Brewitz, L; Handford, PA; Hewitson, KS; Hopkinson, RJ; Jensen, SA; Kershaw, NJ; Kochan, GT; Kramer, H; Krojer, T; McDonough, MA; McNeill, LA; Münzel, M; Oppermann, U; Pfeffer, I; Schofield, CJ1
Brewitz, L; Onisko, BC; Schofield, CJ1

Reviews

2 review(s) available for asparagine and epidermal growth factor

ArticleYear
Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors.
    Blood, 1991, Oct-01, Volume: 78, Issue:7

    Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blood Coagulation Factors; Calcium; Epidermal Growth Factor; Humans; Molecular Sequence Data; Structure-Activity Relationship; Vitamin K

1991
How oxygen makes its presence felt.
    Genes & development, 2002, Jun-15, Volume: 16, Issue:12

    Topics: Animals; Asparagine; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Models, Biological; Nuclear Proteins; Oxygen; Proline; Protein Structure, Tertiary; Transcription Factors; Transcriptional Activation

2002

Other Studies

31 other study(ies) available for asparagine and epidermal growth factor

ArticleYear
Recognition of an antiparallel beta-sheet structure of human epidermal growth factor by its receptor. Site-directed mutagenesis studies of Ala-30 and Asn-32.
    FEBS letters, 1992, May-04, Volume: 302, Issue:1

    Topics: Alanine; Asparagine; Binding, Competitive; Epidermal Growth Factor; ErbB Receptors; Humans; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Protein Conformation

1992
Identification of erythro-beta-hydroxyasparagine in the EGF-like domain of human C1r.
    FEBS letters, 1987, Sep-28, Volume: 222, Issue:1

    Topics: Amino Acids; Asparagine; Complement Activating Enzymes; Complement C1; Complement C1r; Epidermal Growth Factor; Humans; Mass Spectrometry; Peptide Fragments; Thermolysin; Trypsin

1987
Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:22

    Topics: Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Complement Activating Enzymes; Complement C1; Complement C1r; Complement C1s; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Humans; Mucoproteins; Protein Processing, Post-Translational; Sequence Homology, Nucleic Acid; Uromodulin

1987
beta-Hydroxyaspartic acid or beta-hydroxyasparagine in bovine low density lipoprotein receptor and in bovine thrombomodulin.
    The Journal of biological chemistry, 1988, Jan-05, Volume: 263, Issue:1

    Topics: Adrenal Glands; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cattle; Epidermal Growth Factor; Molecular Sequence Data; Receptors, Cell Surface; Receptors, LDL; Receptors, Thrombin; Sequence Homology, Nucleic Acid

1988
The effect of transport system A and N amino acids and of nerve and epidermal growth factors on the induction of ornithine decarboxylase activity.
    Journal of cellular physiology, 1985, Volume: 123, Issue:3

    Topics: Amino Acids; Aminoisobutyric Acids; Asparagine; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Glutamates; Glutamic Acid; Nerve Growth Factors; Neuroblastoma; Ornithine Decarboxylase; Valine

1985
beta-Hydroxyasparagine in domains homologous to the epidermal growth factor precursor in vitamin K-dependent protein S.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:2

    Topics: Amino Acid Sequence; Animals; Asparagine; Cattle; Chromatography, High Pressure Liquid; DNA; Epidermal Growth Factor; Glycoproteins; Hydroxylation; Peptide Fragments; Protein Conformation; Protein Precursors; Protein S; Sequence Homology, Nucleic Acid

1987
Beta-epidermal growth factor is the des-asparaginyl form of the polypeptide.
    The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5

    Topics: Amino Acid Sequence; Asparagine; Cell Division; Chromatography, High Pressure Liquid; Epidermal Growth Factor; ErbB Receptors; Humans; Mass Spectrometry; Receptors, Cell Surface; Structure-Activity Relationship

1985
Evidence for isoaspartyl (deamidated) forms of mouse epidermal growth factor.
    Analytical biochemistry, 1987, Volume: 165, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Chromatography, Gel; Chromatography, High Pressure Liquid; Epidermal Growth Factor; Genetic Variation; Mice; Submandibular Gland

1987
Induction of ornithine decarboxylase activity by insulin and growth factors is mediated by amino acids.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:13

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Fibroblasts; Growth Substances; Insulin; Liver Neoplasms, Experimental; Mice; Nerve Growth Factors; Ornithine Decarboxylase; Platelet-Derived Growth Factor

1985
A single amino acid determines the specificity of a monoclonal antibody which inhibits Plasmodium chabaudi AS in vivo.
    Molecular and biochemical parasitology, 1993, Volume: 62, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Animals; Antibodies, Monoclonal; Antibodies, Protozoan; Antibody Specificity; Asparagine; Base Sequence; DNA, Protozoan; Epidermal Growth Factor; Epitopes; Fluorescent Antibody Technique; Merozoite Surface Protein 1; Mice; Molecular Sequence Data; Mutagenesis; Plasmodium chabaudi; Polymerase Chain Reaction; Proline; Protein Precursors; Protein Structure, Secondary; Protozoan Proteins

1993
Inhibition of ornithine decarboxylase activity but not expression of the gene by cimetidine in intestinal mucosal cells.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Animals; Asparagine; Blood; Cell Division; Chlorpheniramine; Cimetidine; Duodenum; Epidermal Growth Factor; Fasting; Gene Expression Regulation, Enzymologic; Histamine; Intestinal Mucosa; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentagastrin; Ranitidine; Rats; Rats, Sprague-Dawley

1995
Low nidogen affinity of laminin-5 can be attributed to two serine residues in EGF-like motif gamma 2III4.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: Amino Acid Sequence; Asparagine; Base Sequence; Basement Membrane; Binding Sites; Cell Adhesion Molecules; Cell Line; DNA Primers; Epidermal Growth Factor; Humans; Kalinin; Kinetics; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Transfection; Valine

1995
Inhibition of rat prolactin (PRL) storage by coexpression of human PRL.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:8

    Topics: Animals; Asparagine; Biological Transport; Cell Compartmentation; Cytoplasmic Granules; Epidermal Growth Factor; Estradiol; Gene Expression; Humans; Insulin; Models, Molecular; Pituitary Neoplasms; Prolactin; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Species Specificity; Transfection; Tumor Cells, Cultured

1994
Factor IX Fukuoka. Substitution of ASN92 by His in the second epidermal growth factor-like domain results in defective interaction with factors VIIa/X.
    The Journal of biological chemistry, 1993, Nov-15, Volume: 268, Issue:32

    Topics: Adult; Asparagine; Benzamidines; Blood Coagulation Factors; Epidermal Growth Factor; Esterases; Factor IX; Factor VIIa; Factor X; Hemophilia B; Histidine; Humans; Hydrolysis; Kinetics; Male; Mutation; Peptide Mapping

1993
The role of asparagine-32 in forming the receptor-binding epitope of human epidermal growth factor.
    Protein engineering, 1993, Volume: 6, Issue:6

    Topics: Amino Acid Sequence; Asparagine; Epidermal Growth Factor; ErbB Receptors; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Radioligand Assay; Recombinant Fusion Proteins

1993
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
    Molecular and cellular biology, 1997, Volume: 17, Issue:2

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Asparagine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Growth Substances; GTP-Binding Proteins; MAP Kinase Kinase 1; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Nerve Growth Factors; Neurites; Neuropeptides; Oncogene Protein p21(ras); PC12 Cells; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Ras Homolog Enriched in Brain Protein; Rats; Recombinant Proteins; Serine; Signal Transduction

1997
Ca2+ binding to the first epidermal growth factor module of coagulation factor VIIa is important for cofactor interaction and proteolytic function.
    The Journal of biological chemistry, 1997, Jul-11, Volume: 272, Issue:28

    Topics: 1-Carboxyglutamic Acid; Alanine; Animals; Asparagine; Binding Sites; Calcium; CHO Cells; Cricetinae; Epidermal Growth Factor; Factor IX; Factor VIIa; Factor X; Glutamine; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Structure-Activity Relationship

1997
The influence of a scalar-coupled deuterium upon the relaxaton of a 15N Nucleus and its possible exploitation as a probe for side-chain interactions in proteins.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 1997, Volume: 124, Issue:1

    Topics: Asparagine; Deuterium; Epidermal Growth Factor; Fibronectins; Glutamine; Hydrogen Bonding; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Proteins; Recombinant Proteins; Tissue Plasminogen Activator

1997
Solution structure of the N-terminal EGF-like domain from human factor VII.
    Biochemistry, 1998, Jul-28, Volume: 37, Issue:30

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography, X-Ray; Epidermal Growth Factor; Factor VII; Humans; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solutions

1998
Synergistic induction of ornithine decarboxylase by asparagine and gut peptides in intestinal crypt cells.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Animals; Asparagine; Blotting, Western; Cell Line; DNA; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Gastrins; Intestinal Mucosa; Ornithine Decarboxylase; Rats; RNA, Messenger; Transcription, Genetic

1998
Ca2+ in the first epidermal growth factor-like domain of activated factor VII.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9 Suppl 1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Calcium; Epidermal Growth Factor; Factor VIIa; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary

1998
Interaction of asparagine and EGF in the regulation of ornithine decarboxylase in IEC-6 cells.
    The American journal of physiology, 1999, Volume: 276, Issue:3

    Topics: Animals; Asparagine; Cell Line; Cycloheximide; Dactinomycin; Drug Stability; Epidermal Growth Factor; Intestinal Mucosa; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Synthesis Inhibitors; RNA, Messenger; Sirolimus

1999
The epidermal growth factor precursor. A calcium-binding, beta-hydroxyasparagine containing modular protein present on the surface of platelets.
    European journal of biochemistry, 1999, Volume: 260, Issue:1

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; Asparagine; Blood Platelets; Calcium; Calcium-Binding Proteins; Epidermal Growth Factor; Female; Fluorescence; Humans; Hydroxylation; Male; Molecular Sequence Data; Protein Folding; Protein Precursors; Protein Processing, Post-Translational

1999
Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.
    The Journal of biological chemistry, 2002, Jul-12, Volume: 277, Issue:28

    Topics: Alanine; Asparagine; Epidermal Growth Factor; Factor IX; Factor VIIIa; Factor X; Glycine; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Proteins

2002
Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blood Coagulation; Blood Platelets; Cell Line; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Factor IXa; Factor VIIIa; Factor X; Humans; Isoleucine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Platelet Activation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors; Valine

2004
Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor.
    Biochemistry, 2005, Nov-15, Volume: 44, Issue:45

    Topics: Antibodies; Asparagine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epidermal Growth Factor; ErbB Receptors; Glycosylation; Humans; Kinetics; Ligands; Point Mutation; Protein Conformation

2005
Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.
    Biochemistry, 2007, Mar-20, Volume: 46, Issue:11

    Topics: Alanine; Amino Acid Substitution; Arginine; Asparagine; Epidermal Growth Factor; Factor VIIa; Factor X; Humans; Lysine; Models, Molecular; Protein Structure, Tertiary; Thromboplastin

2007
Influences of the N700S thrombospondin-1 polymorphism on protein structure and stability.
    The Journal of biological chemistry, 2008, Jul-18, Volume: 283, Issue:29

    Topics: Amino Acid Sequence; Asparagine; Calcium; Calorimetry, Differential Scanning; Conserved Sequence; Crystallography, X-Ray; Epidermal Growth Factor; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Polymorphism, Genetic; Protein Structure, Tertiary; Sequence Alignment; Temperature; Thrombospondin 1; Thrombospondins

2008
Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding.
    Proteins, 2017, Volume: 85, Issue:4

    Topics: Acetylglucosamine; Asparagine; Binding Sites; Epidermal Growth Factor; ErbB Receptors; Glycosylation; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Thermodynamics

2017
Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.
    Nature communications, 2019, 10-28, Volume: 10, Issue:1

    Topics: Amino Acid Sequence; Asparagine; Calcium-Binding Proteins; Catalytic Domain; Crystallography; Disulfides; Epidermal Growth Factor; Ferrous Compounds; Humans; Membrane Proteins; Mixed Function Oxygenases; Muscle Proteins; Protein Conformation

2019
Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:8

    Topics: Antigens, Ly; Asparagine; Aspartic Acid; Consensus Sequence; Epidermal Growth Factor; Humans; Hydroxylation; Proteomics

2022