asparagine has been researched along with cysteine in 202 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (29.21) | 18.7374 |
| 1990's | 38 (18.81) | 18.2507 |
| 2000's | 73 (36.14) | 29.6817 |
| 2010's | 24 (11.88) | 24.3611 |
| 2020's | 8 (3.96) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Conti, SF; LaMarre, AG; Straley, SC | 1 |
| Becher, R; Gebhart, E | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Larsson, LE; Melin, P; Ragnarsson, U | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| De Groot, RJ; Levinson, R; Strauss, EG; Strauss, JH | 1 |
| Baldwin-Ferro, A; Kroon, DJ; Lalan, P | 1 |
| Asahara, H; Hasegawa, T; Himeno, H; Shimizu, M; Tamura, K | 1 |
| Broze, GJ; Miletich, JP | 1 |
| Meunier, JC; Nury, S | 1 |
| Takemoto, Y | 1 |
| Bielinska, M; Boime, I; Matzuk, MM | 1 |
| Eisenstein, E; Markby, DW; Schachman, HK | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Cullis, PM; Kleanthous, C; Lewendon, A; Murray, IA; Shaw, WV | 1 |
| Klibanov, AM; Tomazic, SJ | 1 |
| Lamm, ME; Lisowska-Bernstein, B; Vassalli, P | 1 |
| Muench, KH; Safille, PA | 1 |
| Abrol, YP; Blumenthal, SG; Conn, EE; Hendrickson, HR | 1 |
| Laycock, MV | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Litwack, G; Miller, JE | 1 |
| Suzuki, N; Tucker, D | 1 |
| Marshall, RD | 1 |
| Fitzgerald, JW | 1 |
| Castric, PA; Conn, EE; Farnden, KJ | 1 |
| Gebhart, E | 1 |
| Liao, TH; Moore, S; Salnikow, J; Stein, WH | 1 |
| Kirschbaum, J; Ratych, OT; Wriston, JC | 1 |
| Bhattacharyya, PK; Khan, AA; Pal, SP; Raghavan, SR | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Buu-Hoï, NP; Hauspie, R; Lambelin, G; Nicolle, J | 1 |
| Coan, MH; Roberts, RC; Travis, J | 1 |
| Husain, I; Norris, RF; Poupard, JA | 1 |
| Asmar, JA; Daghir, NJ; Sifri, M | 1 |
| Brocklehurst, K; Little, G | 1 |
| Grossowicz, N; Lichtenstein, N; Schlesinger, M | 1 |
| Christensen, HN; Koser, BH | 1 |
| Anthony, C; Drabble, WT; Robinson, JH | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Chang, AY; Clark, JM; Reichmann, ME; Spiegelman, S | 1 |
| Houston, MR; Meyer, KH; Thomas, N; Wolf, FT | 1 |
| Husain, SS; Lowe, G | 1 |
| Ruth, RC; Soja, DM; Wold, F | 1 |
| Hirs, CH; Jackson, RL | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Hammerstedt, RH; Robertson, DC; Wood, WA | 1 |
| Kloss, G; Schwarz, E | 1 |
| Paganou, A; Taylor-Papadimitriou, J; Yovanidis, C; Zervas, L | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Schneider, G | 1 |
| McVeigh, I; Morton, K | 1 |
| Munier, RL; Sarrazin, G | 1 |
| Christian, JH; Waltho, JA | 1 |
| Menkès, G | 1 |
| Carlisle, SA; Morse, GE; Willett, NP | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Alter, SC; Cooney, DA; Jayaram, N; Levine, M; Swengros, SG | 1 |
| Font de Valdez, G; Oliver, G; Pesce de Ruiz Holgado, A; Savoy de Giori, G | 1 |
| Johnson, AE | 1 |
| Brennan, TV; Clarke, S | 1 |
| Offer, G; Sessions, R | 1 |
| Boehlein, SK; Richards, NG; Schuster, SM | 1 |
| Blanco-Vaca, F; Gaskell, SJ; Gotto, AM; Gu, ZW; Massey, JB; Pownall, HJ; Yang, CY; Yang, M | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Krogh-Pedersen, H; Petersen, TE; Sørensen, CB | 1 |
| Dötsch, V; Oswald, RE; Wagner, G | 1 |
| Birdsall, DL; Finer-Moore, JS; Liu, L; Mau, T; Santi, DV; Schafmeister, CE; Stroud, RM | 1 |
| Anderson, DC; Brömme, D; Payan, DG; Rossi, AB; Smeekens, SP | 1 |
| Cooper, DN; Girolami, A; Henderson, SC; Kalafatis, M; Luni, S; Millar, DS; Simioni, P | 1 |
| Copeland, NG; Eagleson, B; Hustad, CM; Jenkins, NA; Nakamura, T; Perry, WL; Secrest, L; Swing, DA | 1 |
| Assmann, G; Bakker, HD; Bijvoet, SM; Bruin, T; Funke, H; Hayden, MR; Kastelein, JJ; Ma, Y; Reymer, PW; Wiebusch, H | 1 |
| McFadden, BA; Rehman, A | 1 |
| Ishizaka, K; Mikayama, T; Nakano, T; Sugie, K; Takakura, K; Tomura, T | 1 |
| Austen, KF; Baldasaro, MH; Lam, BK; Penrose, JF; Xu, K | 1 |
| Balis, C; Kyriacou, A; Typas, MA | 1 |
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Enghild, JJ; Olsen, EH; Rahbek-Nielsen, H; Roepstorff, P; Thogersen, IB | 1 |
| Kanematsu, K | 1 |
| Crawford, F; Kappler, J; Liu, CP; Marrack, P | 1 |
| Brown, LS; Dioumaev, AK; Lanyi, JK; Needleman, R | 1 |
| Ameglio, F; Biolcati, G; D'Amato, M; Griso, D; Macrí, A | 1 |
| MacArthur, MW; Thornton, JM | 1 |
| Kaerner, A; Rabenstein, DL | 1 |
| Benner, J; Chong, S; Chute, IC; Evans, TC; Liu, XQ; Mathys, S; Wu, H; Xu, MQ | 1 |
| Carey, PR; Dinakarpandian, D; Hilvert, D; McRee, DE; McTigue, M; Shenoy, BC | 1 |
| Gilman, AG; Mukhopadhyay, S; Posner, BA; Ross, EM; Tesmer, JJ | 1 |
| French, GL; Shannon, KP; Stapleton, PD | 1 |
| Frey, PA; Geeganage, S | 1 |
| Abdel Ghani, EM; Bhakdi, S; Kehoe, M; Palmer, M; Walev, I; Weis, S | 1 |
| Holden, HM; Huang, X; Raushel, FM; Thoden, JB | 1 |
| Erhardt, A; Hassan, M; Häussinger, D; Niederau, C; Osman, Y | 1 |
| Abe, Y; Kim, JH; Kohda, D; Saito, K; Sato, C; Yokoyama, S | 1 |
| Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
| Gitomer, WL; Pak, CY; Reed, BY | 1 |
| Ichishima, E; Lee, BR; Nakajima, T; Nakamura, M; Ohba, Y; Yamauchi, S | 1 |
| Imanaga, I; Iwamoto, T; Shigekawa, M; Uehara, A | 1 |
| Crowder, MW; Taylor, RA; Yanchak, MP | 1 |
| Tyler, MI | 1 |
| Chong, JM; Speicher, DW | 1 |
| Campbell, SJ; Dempsey, CE; Lamble, NV; Sessions, RB | 1 |
| Amrhein, N; Etezady-Esfarjani, T; Macheroux, P; Samland, AK | 1 |
| Chlumsky, LJ; Eschenbrenner, M; Jorns, MS; Khanna, P; Strasser, F | 1 |
| Jain, N; Kostic, M; Pejchal, R; Pochapsky, TC | 1 |
| Brandt, M; Chambers, PA; Daines, RA; Doyle, ML; Gentry, DR; Khandekar, SS; Konstantinidis, AK; Lonsdale, JT; Silverman, C; Van Aller, GS; Warren, P; Xiang, H | 1 |
| Canters, GW; Einsle, O; Jeuken, LJ; Messerschmidt, A; Ubbink, M; van Amsterdam, IM; Verbeet, MP | 1 |
| Boehlein, SK; Hiratake, J; Nakatsu, T; Richards, NG; Schuster, SM; Stewart, JD; Thirumoorthy, R | 1 |
| Chong, JM; Rubin, JS; Speicher, DW; Uren, A | 1 |
| Goto, J; Iida, H; Ikeda, M; Inoue, S; Maruoka, T; Mori, Y; Nagasoe, Y | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Malek, TR; Olosz, F | 1 |
| Carillo, P; Gibon, Y; Krapp, A; Matt, P; Morcuende, R; Müller, C; Scheible, WR; Stitt, M | 1 |
| Chang, CK; Ho, C; Simplaceanu, V | 1 |
| Palecz, B | 1 |
| Armstrong, PB; Husted, LB; Kristensen, L; Quigley, JP; Sorensen, ES; Sottrup-Jensen, L | 1 |
| Schwalbe, RA; Wingo, CS; Xia, SL | 1 |
| Colombo, G; Corti, A; Curnis, F; De Mori, GM; Gasparri, A; Longhi, R; Longoni, C; Sacchi, A | 1 |
| Smith, BJ | 1 |
| Bowen, ME; Brunger, AT; Engelman, DM | 1 |
| Gross, AK; Oprian, DD; Xie, G | 1 |
| Hemmi, H; Katsu, M; Kobayashi, Y; Kojima, S; Kumazaki, T; Kyogoku, Y; Miura, K; Shinohara, F; Yamazaki, T; Yokosawa, H; Yoshida, T | 1 |
| Capogna, M; Emptage, NJ; Ushkaryov, YA; Volynski, KE | 1 |
| Carvajal, CA; Fardella, CE; Gomez-Sanchez, CE; González, A; Gonzalez, AA; Hevia, Mdel P; Lagos, ET; Montero, JA; Mosso, LM; Perez-Acle, TO; Romero, DG; Rosati, MP | 1 |
| Boyer, JL; Harden, TK; Henry, CE; Kreda, S; Mateo, J | 1 |
| DECONNINCK, G; VOETS, JP | 1 |
| SASAKI, T; SHIMURA, K; SUGAWARA, K | 1 |
| HYATT, MT; LEVINSON, HS | 1 |
| Amicosante, G; Anne, C; Bebrone, C; Devreese, B; Franceschini, N; Frère, JM; Galleni, M; Rossolini, GM; Van Beeumen, J; Vanhove, M; Zakhem, M | 1 |
| Balashova, N; Beuve, A; Chang, FJ; Lamothe, M; Shirokov, R | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Bramlett, MR; Feng, J; Kim, EJ; Lindahl, PA | 1 |
| Anderson, KL; Bernier-Fébreau, C; Chen, HA; Cota, E; Du Merle, L; Kur, J; Le Bouguénec, C; Matthews, S; Nowicki, B; Piaatek, R; Simpson, P; Zalewska, B | 1 |
| Austin, MB; Bowman, ME; Ferrer, JL; Izumikawa, M; Moore, BS; Noel, JP; Udwary, DW | 1 |
| Campobasso, N; Gwynn, MN; Kallender, H; Patel, M; Rosenberg, M; Wilding, IE | 1 |
| Jäschke, H; Kleinau, G; Krause, G; Lättig, J; Neumann, S; Paschke, R | 1 |
| Bunn, MW; Cho, SH; Ordal, GW; Szurmant, H | 1 |
| Hirosawa, S; Koyama, T; Nakahara, M; Nakazawa, F; Nishio, M; Shibamiya, A | 1 |
| Endo, Y; Fukai, S; Hori, H; Ishii, R; Nureki, O; Okamoto, H; Watanabe, K; Yokoyama, S | 1 |
| Akerfeldt, KS; Cedervall, T; Halgand, F; Laprévote, O; Linse, S; Thulin, E; Vanbelle, C | 1 |
| Hong, E; Kang, SW; Lee, W; Shin, J; Tanaka, T | 1 |
| Huang, HW; Inoue, M; Kataoka, K; Kitagawa, R; Naruse, D; Sakurai, T | 1 |
| Brockmann, EC; Lamminmäki, U; Saviranta, P | 1 |
| Bloodworth, LM; Hamdan, FF; Han, SJ; Jacobson, KA; Kim, SK; Li, B; Wess, J | 1 |
| Bragason, BT; Palsdottir, A | 1 |
| Bonner, ER; Cahoon, RE; Jez, JM; Knapke, SM | 1 |
| Hoef-Emden, K; Melkonian, M; Tran, HD | 1 |
| Locas, CP; O'Brien, J; Wnorowski, A; Yaylayan, VA | 1 |
| Aoki, H; Ito, Y; Iwama, T; Kawagishi, I; Kawai, K; Sakamoto, H; Yamagata, S | 1 |
| Chen, Z; Liu, Y; Yan, YB; Zhao, TJ; Zhou, HM | 1 |
| Haltia, T; Okkeri, J | 1 |
| Cortes-Funes, H; Gamarra, S; Hitt, R; Manso, L; Medina, PP; Quintela-Fandino, M; Sanchez-Cespedes, M | 1 |
| Frillingos, S; Georgopoulou, E; Karatza, P; Panos, P | 1 |
| Arehart, EJ; Douville, KL; Gleim, SR; Hwa, J; Stitham, J | 1 |
| Gruschus, JM; Jeong, W; Lee, DY; Oho, T; Park, SJ; Rhee, SG; Sung, HJ; Wu, X | 1 |
| Gatti, DL; Kona, F; Kuzmic, P; Martin, P; Xu, X | 1 |
| Dideberg, O; Docquier, JD; Garcia-Saez, I; Rossolini, GM | 1 |
| Gangopadhyay, JP; Ikemoto, N | 1 |
| Basilico, F; Casadio, R; De Palma, A; Martelli, PL; Mauri, PL; Occhipinti, E; Sommaruga, S; Tortora, P; Trisciani, M | 1 |
| Devine, KM; Hohn, MJ; Jester, B; Sheppard, K; Söll, D; Yuan, J | 1 |
| Bierne, H; Bublitz, M; Cossart, P; Heinz, DW; Holland, C; Reichelt, J; Sabet, C; Schubert, WD | 1 |
| Bardien, S; Carr, J; Keyser, R; Lombard, D; Yako, Y | 1 |
| Benfatto, M; Hedman, B; Hocking, RK; Hodgson, KO; Holman, TR; Neidig, ML; Sarangi, R; Solomon, EI | 1 |
| Acton, TB; Aramini, JM; Chen, CX; Fischer, M; Honig, B; Maglaqui, M; Montelione, GT; Nair, R; Nwosu, C; Owens, LA; Rossi, P; Rost, B; Xiao, R | 1 |
| Ding, F; Dokholyan, NV | 1 |
| Gil, GC; Van Cott, KE; Velander, WH | 1 |
| Chen, LL; Qian, SS; Qu, G; Wang, W; Zhang, HY | 1 |
| Harris, JB; Jenko-Praznikar, Z; Krizaj, I; Logonder, U; Pungercar, J; Scott-Davey, T | 1 |
| Ahn, JE; Chi, YH; Dai, SY; Koo, YD; Lee, SY; Yun, DJ; Zhu-Salzman, K | 1 |
| Han, JW; Sholl, DS | 1 |
| Borghese, CM; Harris, RA; McCracken, ML; Trudell, JR | 1 |
| Kigawa, T; Koshiba, S; Matsuda, T; Yokoyama, J | 1 |
| Caspers, P; Danel, F; Härtlein, M; Kron, MA; Nuoffer, C; Page, MG | 1 |
| Aizawa, M; Hamabata, T; Kato, K; Kinjo, S; Matsui, T; Sato, T; Sawada, K; Sugiura, Y; Takita, E | 1 |
| Cantor, JR; Georgiou, G; Stone, EM | 1 |
| Adams, C; Armstrong, V; Blakely, RD; Combs, S; Dawson, ES; DeFelice, LJ; Felts, B; Field, JR; Henry, LK; Iwamoto, H; Jacobs, MT; Kaufmann, K; Meiler, J; Noskov, SY; Rudnick, G; Solis, E; Zdravkovic, I | 1 |
| Fernández, IS; Kay, RR; Neumann, CS; Peak-Chew, SY; Velazquez, F | 1 |
| Glass, AM; Jackson, TA; Krause, ME; Laurence, JS | 2 |
| Christianson, DW; Dugery, RJ; Hai, Y; Healy, D | 1 |
| Balaji, PV; Prabhakar, PK; Rao, KK | 1 |
| Alkazemi, MH; Englert, M; Haruna, K; Liu, Y; Söll, D | 1 |
| Kuang, X; Li, X; Ma, Y; Tang, B; Ye, S; Zhang, C | 1 |
| Axelsen, KB; Costa, SR; López-Marqués, RL; Marek, M; Pomorski, TG; Theorin, L | 1 |
| Andrews-Polymenis, H; Bogomolnaya, L; Chen, JS; McClelland, M; McLaughlin, PA; Porwollik, S; van der Velden, AWM; Yang, HJ | 1 |
| Cygler, M; Gehring, K; Kozlov, G; Wong, K; Xu, C | 1 |
| Liu, WB; Liu, XX; Lu, YX; Ye, BC | 1 |
| Chen, Z; Delinois, LJ; Griebenow, K; Joaquín-Ovalle, FM; Lin, S; Ramirez-Paz, J; Rojas-Nieves, VA; Saxena, M | 1 |
| Chen, H; Feng, Z; Leng, C; Liu, G; Lv, X; Qiao, Y; Sun, J; Zhang, Y | 1 |
| Liu, H; Nowak, C; Patel, R | 1 |
| Konopleva, M; Lorenzi, PL; Tabe, Y | 1 |
| Bacot-Davis, VR; Banavali, NK; Belfort, M; Gao, F; Green, CM; Hu, S; Li, H; Li, Z; Novikova, O; Smith, AD; Thiele, DJ | 1 |
| Butler, M; Ghaffari, N; Gopaluni, B; Jardon, MA; Kennard, M; Krahn, N; Piret, JM; Turner, RFB | 1 |
| Hu, G; Li, Z; Liu, Y; Tian, H; Xu, S; Ye, C; Zhang, H; Zhou, L | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Hlozkova, K; Safrhansova, L; Starkova, J | 1 |
| Cheng, ML; Hsu, WC; Lin, G; Lin, HT; Liu, FC; Lo, CJ | 1 |
| Castro-Fernández, V; Cea, PA; Cid, D; González-Ordenes, F; Guixé, V; Herrera-Morandé, A; Maturana, P; Vallejos-Baccelliere, G; Zamora, RA | 1 |
| Amirjannati, N; Bazrafkan, M; Gilany, K; Henkel, R; Hosseini, E; Moghadasfar, H | 1 |
| Boonrungsiman, S; Chailungkarn, T; Jantraphakorn, Y; Kaewborisuth, C; Lekchareonsuk, P; Lumlertdacha, B; Srisutthisamphan, K; Tanwattana, N; Wanasen, N | 1 |
9 review(s) available for asparagine and cysteine
| Article | Year |
|---|---|
Glycoproteins.
Topics: Amino Acid Sequence; Asparagine; Carbohydrates; Cysteine; Glucosamine; Glycoproteins; Hydroxylysine; Models, Structural; Mucins; Polyribosomes; Protein Conformation; Serine; Threonine | 1972 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
[Ligand recognition in the opioid receptors by modeling methods and the design of opioids].
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cysteine; Drug Design; Humans; Ligands; Models, Molecular; Morphine Derivatives; Protein Structure, Tertiary; Receptors, Opioid; Receptors, Opioid, kappa | 1998 |
Steps towards an integrated view of nitrogen metabolism.
Topics: Amino Acid Oxidoreductases; Amino Acids; Asparagine; Cysteine; Gene Expression Regulation, Plant; Glutamate Dehydrogenase; Glutamine; Glycine; Ketoglutaric Acids; Malates; Nicotiana; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrogen; Oxidation-Reduction; Quaternary Ammonium Compounds; Serine; Signal Transduction | 2002 |
Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cysteine; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Palmitic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Epoprostenol; Serine | 2007 |
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Cysteine; Glutamine; Nitrogenous Group Transferases; Phosphotransferases; RNA, Transfer, Amino Acyl; Selenocysteine | 2008 |
Modifications of recombinant monoclonal antibodies in vivo.
Topics: Animals; Antibodies, Monoclonal; Asparagine; Cysteine; Disulfides; Glutamine; Glycosylation; Humans; Lysine; Pharmaceutical Preparations; Protein Processing, Post-Translational; Recombinant Proteins; Succinimides; Time Factors | 2019 |
Amino acid metabolism in hematologic malignancies and the era of targeted therapy.
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Asparagine; Cysteine; Glutamine; Hematologic Neoplasms; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Tumor Microenvironment | 2019 |
Targeting amino acid metabolism in cancer.
Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms | 2022 |
193 other study(ies) available for asparagine and cysteine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Comparative studies on the specificity of anticlastogenic action in human lymphocytes in culture.
Topics: Asparagine; beta-Aminoethyl Isothiourea; Busulfan; Cells, Cultured; Chromosome Aberrations; Chromosomes; Culture Media; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Humans; Lymphocytes; Methionine; Mutagens; Oxyquinoline; Triaziquone | 1976 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Synthesis of peptides by fragment condensation on a solid support. II. A scheme for preparation of 4,8-disubstituted vasopressins evaluated on 8-arginine-vasopressin.
Topics: Arginine Vasopressin; Asparagine; Cysteine; Peptide Fragments; Peptides; Phenylalanine; Proline; Tyrosine; Vasopressins | 1976 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
Identification of the active site residues in the nsP2 proteinase of Sindbis virus.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cysteine; Cysteine Endopeptidases; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Papain; Protein Biosynthesis; RNA, Viral; Sequence Homology, Amino Acid; Sindbis Virus; Tryptophan; Viral Nonstructural Proteins; Virulence | 1992 |
Identification of sites of degradation in a therapeutic monoclonal antibody by peptide mapping.
Topics: Amino Acid Sequence; Asparagine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Molecular Sequence Data; Muromonab-CD3; Oxidation-Reduction; Peptide Mapping; Temperature | 1992 |
The role of anticodon bases and the discriminator nucleotide in the recognition of some E. coli tRNAs by their aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Asparagine; Bacteriophage T7; Base Sequence; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer; Serine; Structure-Activity Relationship; Substrate Specificity | 1992 |
Beta protein C is not glycosylated at asparagine 329. The rate of translation may influence the frequency of usage at asparagine-X-cysteine sites.
Topics: Amino Acid Sequence; Antibodies; Asparagine; Binding Sites; Blotting, Western; Carcinoma, Hepatocellular; Cysteine; Epitopes; Glycoside Hydrolases; Glycosylation; Humans; Liver Neoplasms; Molecular Sequence Data; Oligosaccharides; Protein Biosynthesis; Protein C; Thrombin; Tumor Cells, Cultured; Warfarin | 1990 |
Molecular mechanisms of the irreversible thermal denaturation of guinea-pig liver transglutaminase.
Topics: Animals; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutamine; Guinea Pigs; Hot Temperature; Liver; Oxidation-Reduction; Protein Denaturation; Transglutaminases | 1990 |
Amino acids with central pressor effect in conscious rats.
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Blood Pressure; Cysteine; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Pressoreceptors; Proline; Rats; Rats, Inbred Strains | 1990 |
Site-specific processing of the N-linked oligosaccharides of the human chorionic gonadotropin alpha subunit.
Topics: Asparagine; Chromatography, High Pressure Liquid; Concanavalin A; Cysteine; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glycoprotein Hormones, alpha Subunit; Glycosylation; Humans; Macromolecular Substances; Mutation; N-Acetylneuraminic Acid; Oligosaccharides; Recombinant Proteins; Sialic Acids; Structure-Activity Relationship; Trypsin | 1989 |
Changes in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.
Topics: Allosteric Regulation; Amino Acids; Asparagine; Aspartate Carbamoyltransferase; Binding Sites; Catalysis; Cysteine; Drug Stability; Escherichia coli; Glutamates; Glutamic Acid; Macromolecular Substances; Mutation; Protein Conformation; Salmonella typhimurium; Structure-Activity Relationship; Zinc | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Substitutions in the active site of chloramphenicol acetyltransferase: role of a conserved aspartate.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Cysteine; Drug Stability; Escherichia coli; Histidine; Hot Temperature; Hydrogen Bonding; Kinetics; Mutation; Structure-Activity Relationship; Sulfhydryl Reagents | 1988 |
Mechanisms of irreversible thermal inactivation of Bacillus alpha-amylases.
Topics: Acetamides; alpha-Amylases; Amides; Asparagine; Bacillus; Chemical Precipitation; Chromatography, High Pressure Liquid; Cysteine; Enzyme Activation; Geobacillus stearothermophilus; Glutamine; Half-Life; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Oxidation-Reduction; Protein Conformation; Sulfhydryl Compounds; Thermodynamics | 1988 |
Cell-free synthesis of rat immunoglobulin. 3. Analysis of the cell-free made chains and of their mode of assembly.
Topics: Acrylates; Animals; Asparagine; Autoradiography; Carbon Isotopes; Cell-Free System; Chromatography; Chromatography, Gel; Cysteine; Electrophoresis; Female; gamma-Globulins; Gels; Histocytochemistry; Immunoglobulin G; Immunoglobulins; Lymph Nodes; Male; Microsomes; Molecular Biology; Rats; Ribosomes; Tritium | 1971 |
Transfer ribonucleic acids in Escherichia coli. Multiplicity and variation.
Topics: Amino Acids; Asparagine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloroquine; Chromatography; Computers; Cysteine; Escherichia coli; Glycine; Histidine; Ligases; Periodic Acid; Proline; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan | 1968 |
Cyanide metabolism in higher plants. 3. The biosynthesis of beta-cyanolanine.
Topics: Alanine; Amino Acids; Asparagine; Carbon Isotopes; Colorimetry; Cyanides; Cysteine; Hydro-Lyases; Hydrogen Cyanide; Plants; Serine; Stimulation, Chemical | 1968 |
The amino acid sequence of cytochrome c-553 from the Chrysophycean alga Monochrysis lutheri.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Autoanalysis; Bacteria; Chymotrypsin; Cysteine; Cytochrome c Group; Dansyl Compounds; Electron Transport; Eukaryota; Glycine; Horses; Hydrolysis; Mitochondria, Muscle; Pepsin A; Peptides; Photosynthesis; Species Specificity; Thiocyanates; Time Factors; Trypsin | 1972 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase.
Topics: Amino Acids; Animals; Antibodies; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Crystallization; Cysteine; Cytoplasm; Diffusion; Dihydroxyphenylalanine; Fenclonine; Glutamates; Isoelectric Focusing; Isoenzymes; Ketoglutaric Acids; Male; Methionine; Mitochondria, Liver; Molecular Weight; Monoiodotyrosine; Oxaloacetates; Phenylpyruvic Acids; Rats; Stereoisomerism; Tryptophan; Tyrosine; Tyrosine Transaminase; Ultracentrifugation; Vibration | 1971 |
Amino acids as olfactory stimuli in freshwater catfish, Ictalurus catus (Linn.).
Topics: Alanine; Amino Acids; Animals; Asparagine; Cysteine; Fishes; Glutamine; Methionine; Olfactory Mucosa; Stereoisomerism | 1971 |
The formation of choline O-sulphate by Pseudomonas C12B and other Pseudomonas species.
Topics: Acetates; Asparagine; Bacteriological Techniques; Choline; Chromatography; Citrates; Culture Media; Cysteine; Electrophoresis; Pseudomonas; Sulfates; Sulfur Radioisotopes; Sulfuric Acids | 1973 |
Cyanide metabolism in higher plants. V. The formation of asparagine from -cyanoalanine.
Topics: Aminohydrolases; Ammonium Sulfate; Asparagine; Bacillus megaterium; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Paper; Colorimetry; Cysteine; Gels; Kinetics; Molecular Weight; Nitriles; Plant Cells; Plants; Species Specificity; Structure-Activity Relationship; Subcellular Fractions; Transferases; Tritium | 1972 |
[Comparative studies on the influence of radioprotectors and amino acids on the chromosome-damaging activity of 8-hydroxyquinoline sulfate in human lymphocytes in vitro].
Topics: Alanine; Amino Acids; Arginine; Asparagine; beta-Aminoethyl Isothiourea; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutamates; Histidine; Humans; Lymphocytes; Methionine; Quinolines | 1973 |
Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.
Topics: Alkylation; Amino Acids; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Deoxyribonucleases; Disulfides; Histidine; Methane; Nitro Compounds; Pancreas; Peptides; Tyrosine | 1973 |
Subunit structure of L-asparaginase from Escherichia coli B.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Cysteine; Detergents; Electrophoresis; Escherichia coli; Ethanol; Formamides; Guanidines; Hydrogen-Ion Concentration; Lymphoma; Methods; Microscopy, Electron; Molecular Weight; Sodium Chloride; Sulfates; Ultracentrifugation; Urea | 1969 |
Studies on Serratia marcescens L-asparaginase.
Topics: Asparaginase; Asparagine; Cysteine; Electrophoresis; Enzyme Induction; Glucose; Glutamates; Isoenzymes; Kinetics; Methionine; Serratia marcescens | 1970 |
[Effects of various amino acids on the sensitivity of 11 strains of Staphylococcus aureus to penicillin G].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Leucine; Methionine; Penicillin G; Penicillin Resistance; Staphylococcus; Stereoisomerism; Tryptophan; Valine | 1969 |
Human pancreatic enzymes. Isolation and properties of a major form of chymotrypsin.
Topics: Acetone; Amino Acids; Animals; Asparagine; Butanones; Calcium Chloride; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis, Disc; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Quaternary Ammonium Compounds; Rabbits; Serine; Species Specificity; Spectrophotometry; Sulfates; Trypsin; Ultracentrifugation; Ultraviolet Rays | 1971 |
Influence of nutrition on the morphology of a strain of Bifidobacterium bifidum.
Topics: Acetates; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Media; Cysteine; Glutamates; Lactobacillus; Mutation; Nutritional Physiological Phenomena; Quaternary Ammonium Compounds; Serine; Surface-Active Agents; Tryptophan | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2'- and with 4,4'- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by
Topics: Asparagine; Cysteine; Disulfides; Histidine; Hydrogen-Ion Concentration; Papain; Pyridines; Sulfhydryl Compounds | 1972 |
Inhibition of murine tumors by carbobenzoxy derivatives of amino acids.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Benzyl Compounds; Carcinoma, Ehrlich Tumor; Cysteine; Formates; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Phenylalanine | 1971 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
Activity and regulation of an acidic amino acid permease of Aspergillus nidulans.
Topics: Ammonia; Asparagine; Aspartic Acid; Aspergillus; Cycloheximide; Cysteine; Glutamates; Glycine; Kinetics; Lysine; Membrane Transport Modulators; Membrane Transport Proteins; Methylamines; Nitrates; Urea | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
The in vitro translation of a monocistronic message.
Topics: Asparagine; Autoradiography; Cysteine; Electrophoresis; Escherichia coli; Genetic Code; Glutamine; In Vitro Techniques; Kinetics; Plant Viruses; RNA, Messenger; Tryptophan; Viral Proteins | 1965 |
Dimorphism in Cladosporium werneckii.
Topics: Agar; Asparagine; Carbon Dioxide; Culture Media; Cysteine; Glucose; Mitosporic Fungi; Nitrogen; Oxygen; Thioglycolates; Yeasts | 1969 |
A reinvestigation of residues 64-68 and 175 in papain. Evidence that residues 64 and 175 are asparagine.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Chromatography, Gel; Chymotrypsin; Cysteine; Histidine; Imidazoles; Papain; Protein Binding | 1970 |
Purification and characterization of enolases from coho (Oncorhynchus kisutch) and chum (Oncorhynchus keta) salmon.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Carboxypeptidases; Cysteine; Cystine; Electrophoresis; Enzyme Activation; Fluorides; Hydro-Lyases; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Magnesium; Molecular Weight; Phosphopyruvate Hydratase; Salmonidae; Tryptophan | 1970 |
The primary structure of porcine pancreatic ribonuclease. II. The amino acid sequence of the reduced S-aminoethylated protein.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Animals; Asparagine; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cyanides; Cysteine; Glutamine; Glycoproteins; Kinetics; Oxidation-Reduction; Pancreatic Juice; Papain; Peptides; Polysaccharides; Rats; Ribonucleases; Species Specificity; Spectrophotometry; Swine; Trypsin | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase. II. Chemical evidence for a three-subunit molecule.
Topics: Aldehyde-Lyases; Alkylation; Amino Acids; Asparagine; Boron Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Detergents; Electrophoresis, Disc; Gluconates; Histidine; Iodoacetates; Molecular Weight; Oxidation-Reduction; Peptides; Pseudomonas; Pyruvates; Sulfuric Acids; Trypsin | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
New methods in peptide synthesis. V. On alpha- and gamma-diphenylmethyl and phenacyl esters of L-glutamic acid.
Topics: Asparagine; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Glutamine; Peptides; Proline | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
Nutritional studies of Histoplasma capsulatum.
Topics: Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamates; Glutathione; Histoplasma; Methionine; Proline; Thioglycolates; Vitamins | 1965 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds | 1966 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
The metabolism of L-asparagine in Asparagus officinalis.
Topics: Alanine; Asparagine; Aspartate Aminotransferases; Aspartate-Ammonia Ligase; Biochemistry; Chromatography, Gel; Cyanides; Cysteine; France; History, 19th Century; Hydro-Lyases; Lyases; Plants; Substrate Specificity | 1980 |
Comparative study of the efficiency of some additives in protecting lactic acid bacteria against freeze-drying.
Topics: Asparagine; Cryoprotective Agents; Cysteine; Dairying; Dextrans; Freeze Drying; Glycerol; Glycerophosphates; Glycogen; Lactobacillus; Polyethylene Glycols; Serum Albumin, Bovine; Sodium Glutamate; Streptococcus | 1983 |
Failure of mineral-vitamin supplements to prevent tansy ragwort (Senecio jacobaea) toxicosis in cattle.
Topics: Animals; Asparagine; Cattle; Cattle Diseases; Cobalt; Copper; Cysteine; Drug Combinations; Minerals; Niacinamide; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Senecio; Vitamins | 1982 |
Effect of adjacent histidine and cysteine residues on the spontaneous degradation of asparaginyl- and aspartyl-containing peptides.
Topics: Adrenocorticotropic Hormone; Amides; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Histidine; Molecular Sequence Data; Oligopeptides; Stereoisomerism | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B. Searching for the catalytic triad.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartate-Ammonia Ligase; Base Sequence; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Glutamine; Humans; Kinetics; Molecular Sequence Data; Nitrogen; Oligodeoxyribonucleotides; Recombinant Proteins; Sequence Homology, Amino Acid | 1994 |
Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links.
Topics: Amino Acid Sequence; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins D; Asparagine; Chromatography, High Pressure Liquid; Chymotrypsin; Cyanogen Bromide; Cysteine; Disulfides; Glycosylation; Humans; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Trypsin | 1994 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
Determination of the disulphide bridge arrangement of bovine histidine-rich glycoprotein.
Topics: Amino Acid Sequence; Animals; Asparagine; Cattle; Cysteine; Disulfides; Glycoproteins; Humans; Molecular Sequence Data; Polymorphism, Genetic; Proteins; Sequence Homology, Amino Acid | 1993 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Topics: Asparagine; Binding Sites; Crystallography, X-Ray; Cysteine; Deoxycytidine Monophosphate; Deoxyuracil Nucleotides; Hydrogen Bonding; Kinetics; Methylation; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation; Recombinant Proteins; Substrate Specificity; Thymidylate Synthase | 1996 |
Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Bleomycin; Cell Line; Cloning, Molecular; Conserved Sequence; Cysteine; Cysteine Endopeptidases; DNA Primers; DNA, Complementary; Drug Resistance, Neoplasm; Gene Expression; Histidine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spodoptera; Substrate Specificity; Transfection | 1996 |
Compound heterozygous protein C deficiency resulting in the presence of only the beta-form of protein C in plasma.
Topics: Adult; Asparagine; Cysteine; Enzyme Activation; Factor Va; Female; Glycosylation; Heterozygote; Humans; Isoenzymes; Male; Pedigree; Point Mutation; Protein C; Protein C Deficiency; Thrombin; Thrombophlebitis; Twins, Monozygotic | 1996 |
Coupled site-directed mutagenesis/transgenesis identifies important functional domains of the mouse agouti protein.
Topics: Agouti Signaling Protein; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cysteine; Female; Hair Color; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Site-Directed; Obesity; Proteins; RNA, Messenger; Transgenes | 1996 |
Compound heterozygosity for a known and a novel defect in the lipoprotein lipase gene (Asp250-->Asn; Ser251-->Cys) resulting in lipoprotein lipase (LPL) deficiency.
Topics: Adolescent; Asparagine; Aspartic Acid; Cysteine; Denmark; DNA; Heterozygote; Humans; Hyperlipoproteinemia Type I; Hypertriglyceridemia; Lipoprotein Lipase; Male; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Serine | 1996 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
High-affinity binding of bioactive glycosylation-inhibiting factor to antigen-primed T cells and natural killer cells.
Topics: Alanine; Animals; Asparagine; Binding Sites; Cell Line; Cysteine; Escherichia coli; Humans; Hybridomas; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Lymphokines; Macrophages; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Point Mutation; Prostatic Secretory Proteins; Recombinant Proteins; Serine; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 1997 |
Site-directed mutagenesis of human leukotriene C4 synthase.
Topics: 5-Lipoxygenase-Activating Proteins; Amino Acid Sequence; Animals; Asparagine; Carrier Proteins; COS Cells; Cysteine; Dimerization; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Sequence Deletion | 1997 |
Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium Gordona bronchialis (Rhodococcus bronchialis).
Topics: Acetylene; Asparagine; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Pyruvates; Rhodococcus | 1997 |
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Posttranslational modifications of human inter-alpha-inhibitor: identification of glycans and disulfide bridges in heavy chains 1 and 2.
Topics: Alpha-Globulins; Asparagine; Carbohydrate Conformation; Cysteine; Disulfides; Glycosylation; Humans; Monosaccharides; Oligosaccharides; Peptides; Polysaccharides; Protein Processing, Post-Translational | 1998 |
T cell positive selection by a high density, low affinity ligand.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Clonal Anergy; Codon; Cysteine; Histocompatibility Antigens Class II; Hybridomas; Interleukin-2; Kinetics; Molecular Sequence Data; Peptide Fragments; Receptors, Antigen, T-Cell, alpha-beta; Restriction Mapping; T-Lymphocytes | 1998 |
Partitioning of free energy gain between the photoisomerized retinal and the protein in bacteriorhodopsin.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteriorhodopsins; Cysteine; Energy Transfer; Halobacterium salinarum; Hydrogen-Ion Concentration; Isomerism; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Retinaldehyde; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 1998 |
Are His63Asp or Cys282Tyr HFE mutations associated with porphyria cutanea tarda? Data of patients from central and southern Italy.
Topics: Asparagine; Cysteine; Histidine; Humans; Italy; Point Mutation; Porphyria Cutanea Tarda; Tyrosine | 1998 |
Protein side-chain conformation: a systematic variation of chi 1 mean values with resolution - a consequence of multiple rotameric states?
Topics: Asparagine; Aspartic Acid; Crystallography, X-Ray; Cysteine; Protein Conformation; Proteins; Rotation; Solubility; Solvents | 1999 |
Stability and structure-forming properties of the two disulfide bonds of alpha-conotoxin GI.
Topics: Animals; Asparagine; Conotoxins; Cysteine; Disulfides; Hydrogen-Ion Concentration; Models, Molecular; Mollusk Venoms; Nuclear Magnetic Resonance, Biomolecular; Peptides; Peptides, Cyclic; Proline; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protons; Structure-Activity Relationship; Sulfhydryl Compounds | 1999 |
Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: facile production of protein building blocks for protein ligation.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Base Sequence; Catalysis; Cyanobacteria; Cysteine; DNA Helicases; DNA Primers; DnaB Helicases; Hydrolysis; Mutation; RNA Splicing | 1999 |
Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins.
Topics: Acylation; Alanine; Amino Acid Substitution; Asparagine; Binding Sites; Crystallography, X-Ray; Cysteine; Esters; Glycine; Kinetics; Models, Molecular; Proline; Protein Conformation; Selenocysteine; Spectrum Analysis, Raman; Static Electricity; Substrate Specificity; Subtilisins | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.
Topics: Amino Acid Substitution; Arginine; Asparagine; Aspartic Acid; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporin Resistance; Cysteine; Enzyme Inhibitors; Leucine; Methionine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Penicillin Resistance; Phenotype | 1999 |
Significance of metal ions in galactose-1-phosphate uridylyltransferase: an essential structural zinc and a nonessential structural iron.
Topics: Asparagine; Binding Sites; Chromatography, Affinity; Circular Dichroism; Cysteine; Dialysis; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Iron; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenanthrolines; Recombinant Proteins; Serine; Structure-Activity Relationship; Triazines; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Uridine Diphosphate Glucose; Zinc | 1999 |
Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation.
Topics: Alanine; Allosteric Regulation; Animals; Asparagine; Bacterial Proteins; Cysteine; Erythrocyte Membrane; Glutamic Acid; Lipid Bilayers; Membrane Proteins; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Conformation; Rabbits; Sheep; Spectrometry, Fluorescence; Streptolysins; Temperature | 1999 |
The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Topics: Apoenzymes; Asparagine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamine; Histidine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Serine; Stereoisomerism | 1999 |
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis].
Topics: Amino Acid Sequence; Asparagine; Chromosomes, Human, Pair 6; Codon; Cysteine; Germany; Hemochromatosis; Heterozygote; Histidine; HLA Antigens; Homozygote; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tyrosine | 1999 |
Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epidermal growth factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carbohydrate Sequence; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Glycosylation; Humans; Lysine; Molecular Sequence Data; Oligosaccharides; Recombinant Proteins; Transfection | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Identification of two novel mutations [P122S (364C>T) and 1601delAC] in the SLC3A1 gene in type I cystinurics.
Topics: Amino Acid Substitution; Amino Acid Transport Systems, Basic; Asparagine; Carrier Proteins; Cysteine; Cystinuria; Female; Genes, Recessive; Homozygote; Humans; Male; Membrane Glycoproteins; Mutation, Missense; Point Mutation; Sequence Deletion; Threonine; Valine | 2000 |
Identification of copper ligands in Aspergillus oryzae tyrosinase by site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspergillus oryzae; Binding Sites; Blotting, Western; Catalysis; Circular Dichroism; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Ligands; Molecular Sequence Data; Monophenol Monooxygenase; Mutagenesis, Site-Directed; Nitrogen; Oxygenases; Peroxidases; Protein Binding; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Sulfur; Thioredoxins | 2000 |
The Na+/Ca2+ exchanger NCX1 has oppositely oriented reentrant loop domains that contain conserved aspartic acids whose mutation alters its apparent Ca2+ affinity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Calcium; Cattle; Cell Membrane; Conserved Sequence; Cricetinae; Cysteine; Dogs; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Recombinant Proteins; Repetitive Sequences, Amino Acid; Sequence Alignment; Sequence Homology, Amino Acid; Sodium; Sodium-Calcium Exchanger; Transfection | 2000 |
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc | 2000 |
Amino acid analysis. An overview.
Topics: Amino Acids; Asparagine; Cysteine; Cystine; Glutamine; Hydrolysis; Sensitivity and Specificity; Stereoisomerism; Tryptophan | 2000 |
Determination of disulfide bond assignments and N-glycosylation sites of the human gastrointestinal carcinoma antigen GA733-2 (CO17-1A, EGP, KS1-4, KSA, and Ep-CAM).
Topics: Amino Acid Sequence; Antigens, Neoplasm; Asparagine; Carcinoma; Cell Adhesion Molecules; Cysteine; Cystine; Disulfides; Epithelial Cell Adhesion Molecule; Gastrointestinal Neoplasms; Glycoproteins; Humans; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Recombinant Proteins; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
The asparagine-stabilized beta-turn of apamin: contribution to structural stability from dynamics simulation and amide hydrogen exchange analysis.
Topics: Amides; Amino Acid Sequence; Amino Acid Substitution; Animals; Apamin; Asparagine; Cysteine; Deuterium; Disulfides; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptides; Protein Conformation; Protein Structure, Secondary; Thermodynamics | 2000 |
Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae.
Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cysteine; Enterobacter cloacae; Enzyme Inhibitors; Fosfomycin; Mutagenesis, Site-Directed; Phosphates; Phosphoenolpyruvate; Recombinant Proteins; Uridine Diphosphate N-Acetylglucosamine | 2001 |
Organization of the multiple coenzymes and subunits and role of the covalent flavin link in the complex heterotetrameric sarcosine oxidase.
Topics: Acetates; Alanine; Arthrobacter; Asparagine; Coenzymes; Corynebacterium; Cysteine; Enzyme Stability; Flavin Mononucleotide; Flavins; Gene Expression Regulation, Bacterial; Glycine; Histidine; Macromolecular Substances; Mutagenesis, Site-Directed; Oxidoreductases, N-Demethylating; Pseudomonas; Recombinant Proteins; Sarcosine Oxidase; Sulfites; Valine | 2001 |
Redox-dependent conformational selection in a Cys4Fe2S2 ferredoxin.
Topics: Amino Acid Sequence; Asparagine; Carbon Isotopes; Cysteine; Ferredoxins; Glycine; Iron; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Mapping; Protein Conformation; Protons; Pseudomonas putida; Spectrophotometry, Ultraviolet; Sulfur; Thermodynamics | 2001 |
Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH).
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Amino Acid Sequence; Anti-Bacterial Agents; Asparagine; Catalysis; Chromatography; Circular Dichroism; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Guanidine; Histidine; Indoles; Inhibitory Concentration 50; Isoelectric Focusing; Kinetics; Models, Chemical; Molecular Sequence Data; Sequence Homology, Amino Acid; Streptococcus pneumoniae; Substrate Specificity; Thiophenes; Ultraviolet Rays | 2001 |
Effects of dimerization on protein electron transfer.
Topics: Algorithms; Asparagine; Azurin; Bacterial Proteins; Base Sequence; Copper; Cysteine; Dimerization; Electron Transport; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Magnetic Resonance Spectroscopy; Molecular Conformation; Mutagenesis; Plasmids; Pseudomonas aeruginosa; Zinc | 2001 |
Characterization of inhibitors acting at the synthetase site of Escherichia coli asparagine synthetase B.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Asparagine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cysteine; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Methionine Sulfoximine; Models, Chemical; Neurotransmitter Agents; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Spectrometry, Mass, Electrospray Ionization | 2001 |
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Electrophoresis, Polyacrylamide Gel; Frizzled Receptors; Glycosylation; Heparin; Humans; Lysine; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Netrin Receptors; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Proteins; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subtilisin; Time Factors; Xenopus | 2002 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Cell Separation; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; DNA, Complementary; Epitopes; Flow Cytometry; Glycine; Humans; Interleukin Receptor Common gamma Subunit; Interleukin-15; Interleukin-2; Interleukin-4; Interleukin-7; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Cytokine; Receptors, Interleukin-7; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2002 |
Effects of amino acid substitutions at beta 131 on the structure and properties of hemoglobin: evidence for communication between alpha 1 beta 1- and alpha 1 beta 2-subunit interfaces.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cysteine; Globins; Glutamine; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Mercuribenzoates; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha 2-macroglobulin. Evidence for two forms differing primarily in their bait region sequences.
Topics: alpha-Macroglobulins; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Carbohydrates; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cloning, Molecular; Cysteine; Disulfides; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Glycosylation; Hemolymph; Horseshoe Crabs; Humans; Hydrogen-Ion Concentration; Methylamines; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium Chloride; Trypsin | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif.
Topics: Amino Acid Motifs; Animals; Arginine; Asparagine; Binding, Competitive; Blotting, Western; Cysteine; Disulfides; Glycine; Humans; Immunohistochemistry; Kinetics; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Temperature; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Chemical cleavage of polypeptides.
Topics: Asparagine; Aspartic Acid; Cysteine; Glycine; Methionine; Peptides; Sequence Analysis, Protein; Tryptophan | 2003 |
Mutational analysis of synaptobrevin transmembrane domain oligomerization.
Topics: Amino Acid Sequence; Animals; Asparagine; Cysteine; Detergents; Dimerization; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Vectors; Glycophorins; Macromolecular Substances; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; R-SNARE Proteins; Rats; Recombinant Fusion Proteins; Synaptic Membranes | 2002 |
An opsin mutant with increased thermal stability.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cattle; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dithiothreitol; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Thermodynamics; Transducin; Transfection | 2003 |
Inhibitory specificity change of the ovomucoid third domain of the silver pheasant upon introduction of an engineered Cys14-Cys39 bond.
Topics: Amino Acid Substitution; Animals; Asparagine; Birds; Cattle; Chymotrypsin; Crystallography, X-Ray; Cysteine; Disulfides; Humans; Leukocyte Elastase; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Pancreatic Elastase; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine Proteinase Inhibitors; Structure-Activity Relationship; Swine | 2003 |
The alpha-latrotoxin mutant LTXN4C enhances spontaneous and evoked transmitter release in CA3 pyramidal neurons.
Topics: Amino Acid Substitution; Animals; Animals, Newborn; Asparagine; Calcium; Culture Techniques; Cysteine; Evoked Potentials; Exocytosis; Hippocampus; Nerve Tissue Proteins; Neurotransmitter Agents; Point Mutation; Pyramidal Cells; Rats; Receptors, Peptide; Spider Venoms; Synaptic Transmission | 2003 |
Two homozygous mutations in the 11 beta-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Asparagine; Aspartic Acid; Base Sequence; Child, Preschool; CHO Cells; Cricetinae; Cysteine; Homozygote; Humans; Hydroxysteroid Dehydrogenases; Male; Mineralocorticoids; Models, Molecular; Mutation; Polymorphism, Single Nucleotide; Threonine | 2003 |
Requirement of Cys399 for processing of the human ecto-ATPase (NTPDase2) and its implications for determination of the activities of splice variants of the enzyme.
Topics: 3T3 Cells; Adenosine Triphosphatases; Alternative Splicing; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Cell Line; CHO Cells; Conserved Sequence; Cricetinae; Cysteine; DNA, Complementary; Glycosylation; Humans; In Vitro Techniques; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Solubility | 2003 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores.
Topics: Alanine; Arginine; Asparagine; Bacillus; Bacillus megaterium; Culture Media; Cysteine; Hot Temperature; Leucine; Nitrates; Nitrogen; Proline; Spores, Bacterial; Valine | 1962 |
Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.
Topics: Aeromonas hydrophila; Asparagine; Bacterial Proteins; Base Sequence; beta-Lactamases; Binding Sites; Cysteine; Kinetics; Molecular Sequence Data; Structure-Activity Relationship; Zinc | 2003 |
Functional characterization of nitric oxide and YC-1 activation of soluble guanylyl cyclase: structural implication for the YC-1 binding site?
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; COS Cells; Cyclic GMP; Cysteine; Cytosol; DNA Mutational Analysis; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitric Oxide; Phenotype; Protein Subunits; Pyrazoles; Pyridines; Rats; Solubility; Tyrosine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
Complete resonance assignments of the 'donor-strand complemented' AfaD: the afimbrial invasin from Diffusely Adherent E. coli.
Topics: Adhesins, Escherichia coli; Asparagine; Bacterial Adhesion; Cysteine; Escherichia coli; Genetic Complementation Test; Glutamine; Hydrogen-Ion Concentration; Integrins; Magnetic Resonance Spectroscopy; Oxygen; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Temperature; Valine | 2004 |
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.
Topics: Acyltransferases; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codon; Crystallography, X-Ray; Cysteine; Escherichia coli; Evolution, Molecular; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Naphthols; Naphthoquinones; Oxalic Acid; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Serine; Streptomyces; Streptomyces coelicolor | 2004 |
Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Cholesterol; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Histidine; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Staphylococcus aureus | 2004 |
Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cell Separation; Computational Biology; COS Cells; Cyclic AMP; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Epitopes; Flow Cytometry; Humans; Interleukin-8; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Thyrotropin; Serine; Signal Transduction; Time Factors; Transfection | 2004 |
Ligand-induced conformational changes in the Bacillus subtilis chemoreceptor McpB determined by disulfide crosslinking in vivo.
Topics: Animals; Asparagine; Bacillus subtilis; Bacterial Proteins; Chemoreceptor Cells; Cross-Linking Reagents; Cysteine; Disulfides; Ligands; Membrane Proteins; Mutation; Protein Conformation | 2004 |
Gradually glycosylated protein C mutants (Arg178Gln and Cys331Arg) are degraded by proteasome after mannose trimming.
Topics: Animals; Arginine; Asparagine; Binding Sites; CHO Cells; Cricetinae; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Genetic Vectors; Glucose; Glutamine; Glycosylation; Immunoprecipitation; Mannose; Mutation; Oligosaccharides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein C; Recombinant Proteins; Time Factors; Transfection | 2004 |
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Chromatography; Chromatography, Affinity; Chromatography, Gel; Circular Dichroism; Cysteine; Kinetics; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; RNA, Transfer; Sequence Homology, Amino Acid; Thermus; Time Factors; tRNA Methyltransferases | 2005 |
Deamidation and disulfide bridge formation in human calbindin D28k with effects on calcium binding.
Topics: Alkylation; Amino Acid Sequence; Asparagine; Aspartic Acid; Calbindin 1; Calbindins; Calcium; Cysteine; Electrophoresis, Agar Gel; Humans; Mass Spectrometry; Molecular Sequence Data; Protein Processing, Post-Translational; S100 Calcium Binding Protein G | 2005 |
Resonance assignments and secondary structureof hPrxVI, a 25 kDa 1-cys human peroxiredoxin enzyme.
Topics: Amino Acid Sequence; Asparagine; Carbon Isotopes; Cysteine; Deuterium; Escherichia coli; Glycine; Humans; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Structure, Secondary; Protons | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Engineering dihydropteroate synthase (DHPS) for efficient expression on M13 phage.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriophage M13; Cysteine; Dihydropteroate Synthase; Immunoassay; Mutation; Peptide Library; Periplasm; Periplasmic Proteins; Protein Engineering | 2005 |
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blotting, Western; Carbachol; Cell Membrane; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dose-Response Relationship, Drug; Kinetics; Leucine; Ligands; Luciferases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Phosphatidylinositols; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, Muscarinic; Serine; Transfection | 2005 |
Processing of ovine PrP(ARQ)C-EGFP chimeras containing Asn138 and Cys151 polymorphisms.
Topics: Amino Acid Substitution; Animals; Asparagine; Cattle; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cysteine; Green Fluorescent Proteins; Mice; Mutagenesis, Site-Directed; Neuroblastoma; Polymorphism, Genetic; Protein Transport; PrPC Proteins; Recombinant Fusion Proteins; Structure-Activity Relationship | 2005 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
Mechanistic pathways of formation of acrylamide from different amino acids.
Topics: Acrylamide; Acrylamides; Acrylates; Amino Acids; Ammonia; Asparagine; Aspartic Acid; beta-Alanine; Carbohydrates; Carnosine; Creatine; Cysteine; Fructose; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Models, Chemical; Pyruvic Acid; Serine; Time Factors | 2005 |
Differential recognition of citrate and a metal-citrate complex by the bacterial chemoreceptor Tcp.
Topics: Allosteric Regulation; Amino Acid Sequence; Asparagine; Chemotaxis; Citric Acid; Cysteine; Escherichia coli; Hydroxylamine; Magnesium; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Quaternary; Protein Structure, Tertiary; Salmonella typhimurium | 2006 |
The evolution from asparagine or threonine to cysteine in position 146 contributes to generation of a more efficient and stable form of muscle creatine kinase in higher vertebrates.
Topics: Amino Acid Sequence; Animals; Anura; Asparagine; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Creatine Kinase, MM Form; Cysteine; Dogs; Enzyme Stability; Evolution, Molecular; Fishes; Humans; Lampreys; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Rats; Sequence Alignment; Skates, Fish; Snakes; Threonine | 2006 |
The metal-binding sites of the zinc-transporting P-type ATPase of Escherichia coli. Lys693 and Asp714 in the seventh and eighth transmembrane segments of ZntA contribute to the coupling of metal binding and ATPase activity.
Topics: Adenosine Triphosphatases; Asparagine; Binding Sites; Copper; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Lysine; Metals; Phosphorylation; Protein Structure, Tertiary; Substrate Specificity; Zinc | 2006 |
DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; Cisplatin; Cysteine; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Endonucleases; Female; Gene Frequency; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Glutamine; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleobase Transport Proteins; Protein Structure, Secondary; Valine; Xanthine | 2006 |
Mutagenesis and modeling of the peroxiredoxin (Prx) complex with the NMR structure of ATP-bound human sulfiredoxin implicate aspartate 187 of Prx I as the catalytic residue in ATP hydrolysis.
Topics: Adenosine Triphosphate; Asparagine; Aspartic Acid; Catalysis; Crystallography, X-Ray; Cysteine; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Peroxiredoxins; Protein Structure, Tertiary | 2006 |
Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases.
Topics: Aldehyde-Lyases; Asparagine; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Kinetics; Metals; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phosphoenolpyruvate; Protein Binding; Substrate Specificity | 2007 |
The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; beta-Lactamases; Binding Sites; Conserved Sequence; Cysteine; Escherichia coli; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Substrate Specificity; Zinc | 2008 |
Interaction of the Lys(3614)-Asn(3643) calmodulin-binding domain with the Cys(4114)-Asn(4142) region of the type 1 ryanodine receptor is involved in the mechanism of Ca2+/agonist-induced channel activation.
Topics: Animals; Asparagine; Calcium; Calcium Channels; Calmodulin; Cysteine; Lysine; Molecular Weight; Protein Binding; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2008 |
A combined approach of mass spectrometry, molecular modeling, and site-directed mutagenesis highlights key structural features responsible for the thermostability of Sulfolobus solfataricus carboxypeptidase.
Topics: Alkylation; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Carboxypeptidases; Cysteine; Disulfides; Enzyme Activation; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oxidation-Reduction; Pepsin A; Protein Engineering; Protein Structure, Secondary; Protein Subunits; Serine; Sulfolobus solfataricus; Thermodynamics; Trypsin | 2008 |
Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.
Topics: Asparagine; Bacterial Proteins; Crystallography, X-Ray; Cysteine; Evolution, Molecular; Leucine-Rich Repeat Proteins; Listeria monocytogenes; Protein Conformation; Protein Folding; Proteins; Repetitive Sequences, Amino Acid; Virulence Factors | 2008 |
Molecular analysis of the parkin gene in South African patients diagnosed with Parkinson's disease.
Topics: Adolescent; Adult; Aged; Arginine; Asparagine; Aspartic Acid; Cysteine; DNA Mutational Analysis; Exons; Female; Gene Frequency; Heterozygote; Humans; Male; Middle Aged; Parkinson Disease; Point Mutation; Sequence Deletion; South Africa; Ubiquitin-Protein Ligases; Young Adult | 2009 |
Geometric structure determination of N694C lipoxygenase: a comparative near-edge X-ray absorption spectroscopy and extended X-ray absorption fine structure study.
Topics: Absorptiometry, Photon; Amino Acid Substitution; Asparagine; Catalytic Domain; Cysteine; Glycine max; Hydrogen Bonding; Inorganic Chemicals; Lipoxygenase; Mutagenesis, Site-Directed; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2008 |
Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Cysteine; Endopeptidases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Protein Structure, Tertiary; Staphylococcus | 2009 |
Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation.
Topics: Animals; Asparagine; Cations, Divalent; Computer Simulation; Copper; Cysteine; Dimerization; Glutamine; Humans; Models, Chemical; Protein Folding; Protein Structure, Secondary; Superoxide Dismutase; Superoxide Dismutase-1; Thermodynamics; Zinc | 2008 |
N-glycosylation microheterogeneity and site occupancy of an Asn-X-Cys sequon in plasma-derived and recombinant protein C.
Topics: Animals; Animals, Genetically Modified; Asparagine; Bioreactors; Chromatography, High Pressure Liquid; Cysteine; Epithelium; Glycopeptides; Glycosylation; Humans; Mammary Glands, Animal; Mass Spectrometry; N-Acetylneuraminic Acid; Plasma; Protein C; Recombinant Proteins; Swine | 2009 |
tRNA-dependent cysteine biosynthetic pathway represents a strategy to increase cysteine contents by preventing it from thermal degradation: thermal adaptation of methanogenic archaea ancestor.
Topics: Adaptation, Physiological; Archaea; Asparagine; Cysteine; Glutamine; Hot Temperature; Methane; RNA, Transfer, Amino Acyl | 2009 |
Ultrastructural evidence for the uptake of a neurotoxic snake venom phospholipase A2 into mammalian motor nerve terminals.
Topics: Animals; Asparagine; Cysteine; Female; Hindlimb; Mice; Motor Neurons; Muscle Fibers, Skeletal; Mutagenesis, Site-Directed; Nanoparticles; Phospholipases A2; Presynaptic Terminals; Viper Venoms | 2009 |
N-glycosylation at non-canonical Asn-X-Cys sequence of an insect recombinant cathepsin B-like counter-defense protein.
Topics: Animals; Asparagine; Cathepsin B; Cysteine; Electrophoresis, Polyacrylamide Gel; Glycoside Hydrolases; Insect Proteins; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins | 2010 |
Enantiospecific adsorption of amino acids on hydroxylated quartz (10 1 0).
Topics: Adsorption; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Quartz; Serine; Stereoisomerism; Thermodynamics | 2010 |
A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics.
Topics: 1-Butanol; 1-Octanol; Alcohols; Amino Acid Substitution; Anesthetics; Animals; Asparagine; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Female; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Isoflurane; Oocytes; Patch-Clamp Techniques; Rats; Receptors, GABA-A; RNA, Complementary; Thiosulfonic Acids; Xenopus laevis | 2010 |
An economical method for producing stable-isotope labeled proteins by the E. coli cell-free system.
Topics: Amino Acids; Asparagine; Cysteine; Escherichia coli; Glutamine; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Biosynthesis; Proteins; Tryptophan | 2010 |
Asparaginyl-tRNA synthetase pre-transfer editing assay.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartate-tRNA Ligase; Brugia malayi; Coloring Agents; Cysteine; Drug Discovery; High-Throughput Screening Assays; Plant Extracts; RNA Editing; RNA, Transfer; RNA, Transfer, Amino Acyl; Rosaniline Dyes; Staphylococcus epidermidis | 2011 |
N-glycosylation at noncanonical Asn-X-Cys sequences in plant cells.
Topics: Arabidopsis; Asparagine; Cysteine; Glycosylation; Lactuca; Plant Cells; Polysaccharides; Shiga Toxin 2 | 2011 |
Expression and biochemical characterization of the human enzyme N-terminal asparagine amidohydrolase.
Topics: Amidohydrolases; Animals; Asparagine; Aspartic Acid; Biocatalysis; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Kinetics; Metals; Mice; Models, Chemical; Molecular Structure; Mutation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2011 |
A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.
Topics: Animals; Asparagine; Chlorides; Cysteine; Electrophysiology; HeLa Cells; Humans; Ions; Mutagenesis, Site-Directed; Neurotransmitter Agents; Norepinephrine; Oocytes; Patch-Clamp Techniques; Plasmids; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Xenopus laevis | 2011 |
Identification of a eukaryotic reductive dechlorinase and characterization of its mechanism of action on its natural substrate.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Base Sequence; Catalytic Domain; Conserved Sequence; Cysteine; Dictyostelium; Gene Knockout Techniques; Glutathione; Glutathione Transferase; Hexanes; Hexanones; Hydrocarbons, Chlorinated; Kinetics; Lyases; Molecular Sequence Data; Oxidoreductases; Protozoan Proteins; Substrate Specificity | 2011 |
Controlling the chiral inversion reaction of the metallopeptide Ni-asparagine-cysteine-cysteine with dioxygen.
Topics: Asparagine; Cysteine; Nickel; Organometallic Compounds; Oxygen; Peptides; Superoxides | 2012 |
Embedding the Ni-SOD mimetic Ni-NCC within a polypeptide sequence alters the specificity of the reaction pathway.
Topics: Asparagine; Cysteine; Nickel; Organometallic Compounds; Peptides; Superoxide Dismutase; Superoxides | 2013 |
Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apoenzymes; Arginase; Asparagine; Binding Sites; Conserved Sequence; Cysteine; Formiminoglutamic Acid; Hydrolases; Manganese; Metalloproteins; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Conformation; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Trypanosoma cruzi | 2013 |
The Cys78-Asn88 loop region of the Campylobacter jejuni CstII is essential for α2,3-sialyltransferase activity: analysis of the His85 mutants.
Topics: Asparagine; Campylobacter jejuni; Cysteine; Enzyme Activation; Enzyme Stability; Histidine; Mutation; Sialyltransferases; Temperature | 2014 |
Engineering the elongation factor Tu for efficient selenoprotein synthesis.
Topics: Asparagine; Bacterial Proteins; Binding Sites; Catalytic Domain; Cysteine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Peptide Elongation Factor Tu; Protein Biosynthesis; Protein Engineering; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Selenoproteins | 2014 |
A new type of surface-enhanced Raman scattering sensor for the enantioselective recognition of d/l-cysteine and d/l-asparagine based on a helically arranged Ag NPs@homochiral MOF.
Topics: Asparagine; Cysteine; Metal Nanoparticles; Models, Molecular; Organometallic Compounds; Silver; Spectrum Analysis, Raman; Stereoisomerism | 2016 |
Role of post-translational modifications at the β-subunit ectodomain in complex association with a promiscuous plant P4-ATPase.
Topics: Adenosine Triphosphatases; Asparagine; Cysteine; Mutation; Nicotiana; Plant Proteins; Plants, Genetically Modified; Protein Binding; Protein Domains; Protein Processing, Post-Translational; Protein Subunits; Protein Transport | 2016 |
Contribution of Asparagine Catabolism to Salmonella Virulence.
Topics: Animals; Asparaginase; Asparagine; Catalysis; Cysteine; Disease Models, Animal; Enzyme Stability; Female; Lymphocyte Activation; Macrophages; Mice; Mutation; Nitrogen; Salmonella; Salmonella Infections; Salmonella Infections, Animal; Salmonella typhimurium; T-Lymphocytes; Virulence; Virulence Factors | 2017 |
Crystal Structure of the Salmonella Typhimurium Effector GtgE.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Folding; Protein Structure, Secondary; rab GTP-Binding Proteins; Salmonella typhimurium | 2016 |
Identification and characterization of two types of amino acid-regulated acetyltransferases in actinobacteria.
Topics: Acetyltransferases; Asparagine; Bacterial Proteins; Cysteine; Protein Processing, Post-Translational; Streptomyces | 2017 |
Thiol-maleimide poly(ethylene glycol) crosslinking of L-asparaginase subunits at recombinant cysteine residues introduced by mutagenesis.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Binding Sites; Biocatalysis; Cross-Linking Reagents; Cysteine; Gene Expression; Glycoconjugates; Humans; Kinetics; Maleimides; Models, Molecular; Mutagenesis, Site-Directed; Polyethylene Glycols; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Solubility; Substrate Specificity; Sulfhydryl Compounds | 2018 |
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutamine; Glutathione; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Metabolome; Methionine; Nitrogen; Streptococcus thermophilus | 2018 |
Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.
Topics: Asparagine; Binding Sites; Cloning, Molecular; Copper; Cryptococcus neoformans; Crystallography, X-Ray; Cysteine; Escherichia coli; Fungal Proteins; Gene Expression; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Inteins; Maltose-Binding Proteins; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Fusion Proteins; RNA Splicing; RNA-Binding Proteins; Sequence Alignment; Spliceosomes; Structural Homology, Protein; Zinc | 2019 |
Effects of cysteine, asparagine, or glutamine limitations in Chinese hamster ovary cell batch and fed-batch cultures.
Topics: Animals; Antibody Formation; Asparagine; Batch Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Cysteine; Glutamine; Glycosylation; Humans; Immunoglobulin G | 2020 |
Metabonomic Insights into the Sperm Activation Mechanisms in Ricefield Eel (
Topics: Animals; Asparagine; China; Cysteine; Eels; Energy Metabolism; Fertilization; Male; Metabolome; Metabolomics; Oxidative Stress; Reactive Oxygen Species; Sperm Motility; Spermatozoa | 2020 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Exploring the aging process of cognitively healthy adults by analyzing cerebrospinal fluid metabolomics using liquid chromatography-tandem mass spectrometry.
Topics: Adult; Aged; Aged, 80 and over; Aging; Asparagine; Chromatography, Liquid; Cognition; Cohort Studies; Cysteine; Fasting; Female; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Metabolome; Middle Aged; Pantothenic Acid; Tandem Mass Spectrometry; Young Adult | 2023 |
Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Asparagine; Cysteine; Glucokinase; Glucose; Humans; Kinetics; Phylogeny; Sugars | 2023 |
Targeted Amino Acids Profiling of Human Seminal Plasma from Teratozoospermia Patients Using LC-MS/MS.
Topics: Amino Acids; Asparagine; Biomarkers; Case-Control Studies; Chromatography, Liquid; Cysteine; Glutamine; Glycine; Humans; Male; Semen; Tandem Mass Spectrometry; Teratozoospermia; Tryptophan; Valine | 2023 |
Human BST2 inhibits rabies virus release independently of cysteine-linked dimerization and asparagine-linked glycosylation.
Topics: Antigens, CD; Asparagine; Bone Marrow Stromal Antigen 2; Cysteine; Dimerization; Glycosylation; GPI-Linked Proteins; Humans; Rabies; Rabies virus; Virus Release | 2023 |