asparagine has been researched along with aspartate-beta-hydroxamate in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.43) | 18.7374 |
| 1990's | 18 (51.43) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 6 (17.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flagg, SD; Littman, L; Munir, M; Robinson, MB | 1 |
| Ormandy, GC | 1 |
| Briggs, RS; Porter, RH; Roberts, PJ | 1 |
| Flott, B; Seifert, W | 1 |
| Goetsch, L; Grange, J; Hamedi-Sangsari, F; Malley, S; Navarro, C; Thomasset, N; Tournaire, R; Vila, J | 1 |
| Beacham, IR; Burns, DM; Jerlström, PG; Spring, KJ | 1 |
| Arfin, SM; Chiang, CS; Gantt, JS; Hatfield, GW | 1 |
| Andrulis, IL; Siminovitch, L | 2 |
| Hamedi-Sangsari, F; Lockhart, BP; Privat, A; Vignon, J; Vila, J | 2 |
| Ishida, M; Kataoka, K; Nakamura, Y; Shinozaki, H | 1 |
| Djamgoz, MB; Stephens, GJ; Wilkin, GP | 1 |
| Arnaud, S; Blanchet, JP; Doré, JF; Grange, J; Hamedi-Sangsari, F; Malley, S; Tournaire, R; Vila, J | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Grange, JM; Hamedi-Sangsari, F; Malley, SD; Vila, JR | 1 |
| Dore, JF; Grange, J; Hamedi-Sangsari, F; Malley, S; Thomasset, N; Tournaire, R; Vila, J | 1 |
| Fix, AS; Olney, JW; Price, MT; Romano, C; Tizzano, JP | 1 |
| Koerner, JF; Roon, RJ | 1 |
| Deitmer, JW; Schneider, HP | 1 |
| Balis, C; Kyriacou, A; Typas, MA | 1 |
| El-Sherif, Y; Khan, T; Singh, N; Wieraszko, A | 1 |
| Boos, J; Hempel, G; Lanvers, C; Vieira Pinheiro, JP; Wuerthwein, G | 1 |
| Careri, M; Dallavalle, F; Tegoni, M; Zagnoni, I | 1 |
| Lorca, G; Saier, MH; Winnen, B | 1 |
| Hou, WC; Lin, YS; Liu, DZ | 1 |
| Chantepie, J; Charlot, C; Hamedi-Sangsari, F; Quash, G; Roch, AM; Thomas, V; Vila, J | 1 |
| Bonomo, J; Gill, RT; Lynch, MD; Price, JV; Warnecke, T | 1 |
| Cígler, P; Hoffman, HE; Jirásková, J; Konvalinka, J; Sanda, M; Schraml, J | 1 |
| Caspers, P; Danel, F; Härtlein, M; Kron, MA; Nuoffer, C; Page, MG | 1 |
| Noda, T; Ortiz, V; Shimoda, M; Sirica, AE; Wands, JR | 1 |
| Chen, S; Du, J; Jin, H; Liu, Z; Tang, C; Zhao, B; Zheng, S | 1 |
| Guo, HC; Lakshminarasimhan, D; Pande, S | 1 |
| Barber, PS; Cilli, EM; Lopes, AM; Magri, A; Pereira, JFB; Pessoa, A; Soler, MF | 1 |
| Chen, J; Jiang, H; Lian, M; Liu, Y; Shan, G; Wu, M; Wu, S; Xu, Y; Zhang, H | 1 |
35 other study(ies) available for asparagine and aspartate-beta-hydroxamate
| Article | Year |
|---|---|
Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis.
Topics: Alanine; Allosteric Site; Animals; Asparagine; Biological Transport, Active; Drug Interactions; Hippocampus; Hydrolysis; Ibotenic Acid; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1992 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in rat hippocampus by L-aspartate-beta-hydroxamate.
Topics: Animals; Asparagine; Carbachol; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1992 |
L-aspartate-beta-hydroxamate exhibits mixed agonist/antagonist activity at the glutamate metabotropic receptor in rat neonatal cerebrocortial slices.
Topics: Animals; Animals, Newborn; Asparagine; Cerebral Cortex; Excitatory Amino Acid Antagonists; In Vitro Techniques; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism | 1992 |
Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain.
Topics: Animals; Asparagine; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Chlorides; Glutamates; Glutamic Acid; Ion Channels; Kinetics; Potassium; Quisqualic Acid; Rats; Sodium | 1991 |
Anti-tumoral activity of L and D isomers of aspartic acid beta-hydroxamate on L5178Y leukemia.
Topics: Animals; Asparagine; Aspartic Acid; Drug Screening Assays, Antitumor; Isomerism; Leukemia L5178; Mice; Mice, Inbred DBA | 1991 |
L-asparaginase genes in Escherichia coli: isolation of mutants and characterization of the ansA gene and its protein product.
Topics: Asparaginase; Asparagine; Cross Reactions; DNA, Bacterial; DNA, Recombinant; Escherichia coli; Genes, Bacterial; Mutation; Plasmids; Recombination, Genetic; Sequence Homology, Nucleic Acid | 1986 |
Chinese hamster ovary cells resistant to beta-aspartylhydroxamate contain increased levels of asparagine synthetase.
Topics: Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartate-Ammonia Ligase; Aspartate-tRNA Ligase; Cell Division; Cell Line; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Resistance; Female; Genetic Variation; Ligases; Mutation; Ovary; RNA, Transfer, Amino Acyl | 1980 |
DNA-mediated gene transfer of beta-aspartylhydroxamate resistance into Chinese hamster ovary cells.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cricetinae; Cricetulus; DNA, Recombinant; Drug Resistance; Female; Gene Expression Regulation; Genes; Ligases; Ovary; Temperature; Transformation, Genetic | 1981 |
Isolation and characterization of Chinese hamster ovary cell mutants resistant to the amino acid analog beta-aspartyl hydroxamate.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cell Line; Cell Separation; Cricetinae; Cricetulus; Drug Resistance; Female; Gene Expression Regulation; Genes, Dominant; Genes, Recessive; Kinetics; Ligases; Mutation; Ovary | 1982 |
A N-methyl-D-aspartate receptor-mediated neurotoxic effect of aspartate-based hydroxamate compounds in rat primary neuronal cultures.
Topics: Animals; Antiviral Agents; Asparagine; Cells, Cultured; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
(2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
Topics: Amino Acids, Dicarboxylic; Animals; Anti-Bacterial Agents; Asparagine; Aspartic Acid; Astrocytes; Cell Membrane; Cells, Cultured; Depression, Chemical; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Neuroglia; Neurons; Pregnancy; Rats; Rats, Wistar; Stereoisomerism; Synaptosomes | 1993 |
A patch clamp study of excitatory amino acid effects on cortical astrocyte subtypes in culture.
Topics: Action Potentials; Animals; Asparagine; Astrocytes; Biological Transport, Active; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Rats; Receptors, Amino Acid | 1993 |
Antiproliferative effect of D-aspartic acid beta-hydroxamate (DAH) on Friend virus-infected erythropoietic progenitor cells.
Topics: Animals; Antineoplastic Agents; Asparagine; Cell Division; Depression, Chemical; Drug Screening Assays, Antitumor; Erythroid Precursor Cells; Erythropoiesis; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred DBA; Polycythemia; Retroviridae Infections; Spleen; Splenomegaly; Survival Rate; Tumor Cells, Cultured; Tumor Virus Infections | 1994 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes.
Topics: Antiviral Agents; Asparagine; Aspartic Acid; Cell Survival; Cells, Cultured; Didanosine; Drug Synergism; HIV Infections; Humans; Hydroxyurea; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Virus Replication; Zalcitabine; Zidovudine | 1994 |
Therapeutic effects of D-aspartic acid beta-hydroxamate (DAH) on Friend erythroleukemia.
Topics: Animals; Antiviral Agents; Asparagine; Cell Division; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred DBA; Polycythemia; Retroviridae Infections; Splenomegaly; Time Factors; Tumor Cells, Cultured; Tumor Virus Infections; Viremia | 1994 |
Neurotoxic effect of the anti-HIV drug D-aspartate beta-hydroxamate for rat primary neuronal cultures: attenuation by N-methyl-D-aspartate (NMDA) antagonists.
Topics: Animals; Asparagine; Cells, Cultured; Cerebral Cortex; HIV Infections; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley | 1993 |
Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents.
Topics: Alanine; Animals; Animals, Newborn; Asparagine; Brain Diseases; Excitatory Amino Acid Antagonists; Isomerism; Mice; Mice, Inbred ICR; Nerve Degeneration; Optic Nerve; Phosphoserine; Rats; Receptors, Metabotropic Glutamate; Retinal Degeneration; Second Messenger Systems | 1995 |
Persistent depression of synaptic responses occurs in quisqualate sensitized hippocampal slices after exposure to L-aspartate-beta-hydroxamate.
Topics: 2-Aminoadipic Acid; Action Potentials; Alanine; Animals; Asparagine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hippocampus; Hydroxamic Acids; In Vitro Techniques; Male; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1996 |
Intracellular acidification of the leech giant glial cell evoked by glutamate and aspartate.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Invertebrate; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Leeches; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Sodium | 1997 |
Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium Gordona bronchialis (Rhodococcus bronchialis).
Topics: Acetylene; Asparagine; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Pyruvates; Rhodococcus | 1997 |
The effect of glutamate uptake inhibitors on hippocampal evoked potentials in vitro.
Topics: Animals; Asparagine; Dicarboxylic Acids; Evoked Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Pyrrolidines | 1999 |
Analytical validation of a microplate reader-based method for the therapeutic drug monitoring of L-asparaginase in human serum.
Topics: Asparaginase; Asparagine; Calibration; Dickeya chrysanthemi; Drug Monitoring; Drug Stability; Escherichia coli; Humans; Hydrolysis; Kinetics; Linear Models; Microchemistry; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Pentacopper(II) 12-metallacrown-4 complexes with alpha- and beta-aminohydroxamic acids in aqueous solution: a reinvestigation.
Topics: Alanine; Antineoplastic Agents; Antiviral Agents; Asparagine; Binding Sites; Copper; Electrochemistry; Hydroxamic Acids; Molecular Structure; Solutions; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis | 2003 |
Identification of the L-aspartate transporter in Bacillus subtilis.
Topics: Amino Acid Transport Systems, Acidic; Amino Acids; Asparagine; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Cell Division; Cloning, Molecular; Glutamic Acid; Mutation; Phylogeny; Recombinant Fusion Proteins; Substrate Specificity | 2003 |
Monohydroxamates of aspartic acid and glutamic acid exhibit antioxidant and angiotensin converting enzyme inhibitory activities.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Asparagine; Biphenyl Compounds; DNA Damage; Free Radical Scavengers; Glutamates; Hydroxamic Acids; Hydroxyl Radical; Picrates; Superoxides | 2004 |
4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Asparagine; Cell Proliferation; D-Amino-Acid Oxidase; DNA Fragmentation; Fibroblasts; Glutamine; HeLa Cells; Humans; Liver; Methionine; Pyridoxal; Pyridoxamine; Rats; Transaminases | 2004 |
Genome-scale analysis of anti-metabolite directed strain engineering.
Topics: Alanine; Algorithms; Antimetabolites; Asparagine; Aspartic Acid; Cloning, Molecular; Contig Mapping; Escherichia coli; Gene Expression Profiling; Gene Frequency; Genetic Engineering; Genome, Bacterial; Genomic Library; Genomics; Lac Operon; Mutagenesis, Insertional; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Phenotype; Plasmids; Selection, Genetic | 2008 |
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor.
Topics: Animals; Asparagine; Binding, Competitive; Enzyme Inhibitors; Hydroxamic Acids; Mice; Oximes; Pyridoxal Phosphate; Racemases and Epimerases; Structure-Activity Relationship | 2009 |
Asparaginyl-tRNA synthetase pre-transfer editing assay.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartate-tRNA Ligase; Brugia malayi; Coloring Agents; Cysteine; Drug Discovery; High-Throughput Screening Assays; Plant Extracts; RNA Editing; RNA, Transfer; RNA, Transfer, Amino Acyl; Rosaniline Dyes; Staphylococcus epidermidis | 2011 |
Immunization with aspartate-β-hydroxylase-loaded dendritic cells produces antitumor effects in a rat model of intrahepatic cholangiocarcinoma.
Topics: Adoptive Transfer; Animals; Asparagine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Division; Cells, Cultured; Cholangiocarcinoma; Dendritic Cells; Disease Models, Animal; Humans; Immunization; Interleukin-12; Male; Rats; Rats, Inbred F344; Recombinant Proteins; Spleen | 2012 |
Endogeous sulfur dioxide protects against oleic acid-induced acute lung injury in association with inhibition of oxidative stress in rats.
Topics: Acetylcysteine; Acute Lung Injury; Analysis of Variance; Animals; Apoptosis; Asparagine; Aspartate Aminotransferases; Blotting, Western; Colorimetry; Fluorescence; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Oleic Acid; Oxidative Stress; Rats; Reactive Oxygen Species; Sulfur Dioxide | 2015 |
Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate.
Topics: Asparagine; Aspartylglucosaminuria; Aspartylglucosylaminase; Biocatalysis; Crystallization; Crystallography, X-Ray; Disaccharides; Glycopeptides; Humans; Hydrolysis; Lysosomes; Models, Molecular; Mutant Proteins; Mutation; Substrate Specificity | 2017 |
A critical analysis of L-asparaginase activity quantification methods-colorimetric methods versus high-performance liquid chromatography.
Topics: Asparaginase; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Colorimetry; Enzyme Assays; Humans | 2018 |
Intravenous injection of l-aspartic acid β-hydroxamate attenuates choroidal neovascularization via anti-VEGF and anti-inflammation.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Asparagine; Cells, Cultured; Choroid; Choroidal Neovascularization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Inflammation; Injections, Intravenous; Intravitreal Injections; Mice; Mice, Inbred C57BL; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A; Visual Acuity | 2019 |