asoxime chloride has been researched along with trimedoxime bromide in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 13 (40.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dohnal, V; Dolezal, M; Jun, D; Kuca, K; Musilek, K | 1 |
| Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K | 1 |
| Cabal, J; Gunn-Moore, F; Jun, D; Kassa, J; Kuca, K; Musilek, K | 1 |
| Dohnal, V; Jun, D; Kuca, K; Kucera, J; Musilek, K; Opletalova, V | 1 |
| Dohnal, V; Dolezal, M; Gunn-Moore, F; Holas, O; Horova, A; Komloova, M; Kuca, K; Musilek, K; Pohanka, M | 1 |
| Acharya, J; Karade, HN; Kaushik, MP; Valiveti, AK | 1 |
| Balderman, D; Galron, R; Kloog, Y; Sokolovsky, M | 1 |
| Dawson, RM; Poretski, M | 1 |
| Ardab'eva, TV; Khramova, EA; Prozorovskiĭ, VB | 1 |
| Jokanović, M; Jovanović, D; Kilibarda, V; Maksimović, M; Savić, D | 1 |
| Maksimovic, M; Milic, B; Nedelijkovic, M | 1 |
| Doctor, BP; Genovese, RF | 1 |
| Calić, M; Kovarik, Z; Sinko, G | 1 |
| Cabal, J; Hrabinova, M; Jun, D; Kassa, J; Kuca, K | 1 |
| Reiner, E; Simeon-Rudolf, V | 1 |
| Bajgar, J; Jun, D; Kuca, K | 1 |
| Karasova, J; Kassa, J; Kuca, K; Musilek, K | 1 |
| Humlicek, V; Kassa, J | 1 |
| Jung, YS; Karasova, J; Kassa, J; Kuca, K; Musilek, K | 1 |
| Hasan, MY; Kuca, K; Lorke, DE; Nurulain, SM; Petroianu, GA; Schmitt, A | 1 |
| Bajgar, J; Caisberger, F; Karasova, JZ; Kassa, J | 1 |
| Bajgar, J; Blaha, V; Cabal, J; Fusek, J; Karasova, JZ; Kassa, J; Tesarova, S | 1 |
| Caisberger, F; Jung, YS; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K | 1 |
| Bajgar, J; Jung, YS; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K; Pavlikova, R | 1 |
| Fišar, Z; Hroudová, J; Korábečný, J; Kuča, K; Musílek, K | 1 |
| Caisberger, F; Karasova, JZ; Kassa, J; Sepsova, V | 1 |
| Karasova, JZ; Kassa, J; Tesarova, S | 1 |
| Kassa, J; Kuca, K; Pikula, J; Pohanka, M | 1 |
| Bajgar, J; Caisberger, F; Karasova, JZ; Kassa, J; Sepsova, V | 1 |
| Kassa, J; Kunesova, G | 1 |
| Bajgar, J; Caisberger, F; Karasová, JZ; Kassa, J; Pavlíková, R | 1 |
| Antonijevic, B; Antonijevic, E; Djukic-Cosic, D; Kosvancova, A; Kotur-Stevuljevic, J; Kuca, K; Musilek, K; Spasojevic-Kalimanovska, V | 1 |
32 other study(ies) available for asoxime chloride and trimedoxime bromide
| Article | Year |
|---|---|
Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Hydrocarbons, Brominated; Nitrogen; Oximes; Pyridinium Compounds; Rats | 2006 |
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Cholinesterase Inhibitors; Nitriles; Organophosphates; Paraoxon; Pyridinium Compounds | 2006 |
Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).
Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Kinetics; Organophosphates; Oximes; Pyridinium Compounds; Structure-Activity Relationship | 2007 |
Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators; Models, Biological; Molecular Structure; Organophosphates; Paraoxon; Pyridinium Compounds; Rats; Stereoisomerism; Structure-Activity Relationship | 2008 |
Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.
Topics: Acetylcholinesterase; Binding Sites; Catalytic Domain; Cholinesterase Reactivators; Computer Simulation; Humans; Hydrogen Bonding; Organophosphorus Compounds; Oximes; Structure-Activity Relationship | 2011 |
Synthesis and in vitro evaluation of bis-quaternary 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide derivatives as reactivators against sarin and VX inhibited human acetylcholinesterase (hAChE).
Topics: Acetamides; Acetylcholinesterase; Enzyme Assays; Humans; Kinetics; Organothiophosphorus Compounds; Oximes; Protein Binding; Pyridines; Sarin | 2014 |
Reversible and irreversible inhibition of rat brain muscarinic receptors is related to different substitutions on bisquaternary pyridinium oximes.
Topics: Animals; Benzilates; Binding, Competitive; Brain Stem; Cell-Free System; Obidoxime Chloride; Oximes; Parasympatholytics; Piperidines; Pyridinium Compounds; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Trimedoxime | 1985 |
Carbamylated acetylcholinesterase: acceleration of decarbamylation by bispyridinium oximes.
Topics: Acetylcholinesterase; Animals; Brain; Carbamates; Cattle; Erythrocytes; Humans; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rabbits; Trimedoxime | 1985 |
[Trial of cholinesterase reactivators as proserine antagonists].
Topics: Animals; Antidotes; Atropine; Butanones; Cholinesterase Reactivators; Diphenylacetic Acids; Drug Synergism; Male; Mice; Neostigmine; Obidoxime Chloride; Oximes; Parasympatholytics; Pralidoxime Compounds; Pyridinium Compounds; Trimedoxime | 1983 |
Oxime-induced reactivation of acetylcholinesterase inhibited by phosphoramidates.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Kinetics; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Trimedoxime | 1996 |
Trimedoxime and HI-6: kinetic comparison after intravenous administration to mice.
Topics: Animals; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Half-Life; Injections, Intravenous; Mice; Oximes; Pyridinium Compounds; Trimedoxime | 1996 |
Behavioral comparison of the oximes TMB-4, 2-PAM, and HI-6 in rats using operant conditioning.
Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Trimedoxime | 1997 |
para- and ortho-Pyridinium aldoximes in reaction with acetylthiocholine.
Topics: Acetylthiocholine; Oximes; Pyridinium Compounds; Thermodynamics; Trimedoxime | 2006 |
In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2006 |
Pyridinium, imidazolium and quinuclidinium compounds: toxicity and antidotal effects against the nerve agents Tabun and Soman.
Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Mice; Obidoxime Chloride; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Trimedoxime | 2006 |
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime | 2007 |
An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Injections, Intramuscular; Lethal Dose 50; Male; Mice; Molecular Structure; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Species Specificity; Toxicity Tests, Acute; Trimedoxime | 2008 |
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, trimedoxime, HI-6) to counteract acute toxic effects of tabun and cyclosarin in mice.
Topics: Animals; Antidotes; Atropine; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Trimedoxime | 2008 |
A comparison of the therapeutic and reactivating efficacy of newly developed oximes (K117, K127) and currently available oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Cholinesterase Inhibitors; Diaphragm; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2008 |
Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6.
Topics: Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Male; Obidoxime Chloride; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2009 |
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice.
Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Male; Mice; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Trimedoxime | 2009 |
Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo.
Topics: Acetylcholinesterase; Animals; Central Nervous System; Cholinesterase Reactivators; Drug Therapy, Combination; Enzyme Activation; Female; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2010 |
A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice.
Topics: Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Mice; Obidoxime Chloride; Organophosphates; Oximes; Pyridinium Compounds; Rats; Trimedoxime | 2010 |
A comparison of reactivating and therapeutic efficacy of bispyridinium acetylcholinesterase reactivator KR-22934 with the oxime K203 and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Mice; Obidoxime Chloride; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2011 |
In vitro effects of acetylcholinesterase reactivators on monoamine oxidase activity.
Topics: Animals; Brain; Cholinesterase Reactivators; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Obidoxime Chloride; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Swine; Trimedoxime | 2011 |
The benefit of combinations of oximes for the reactivating and therapeutic efficacy of antidotal treatment of sarin poisoning in rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Chemical Warfare Agents; Drug Therapy, Combination; Male; Mice; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Trimedoxime | 2011 |
A comparison of the neuroprotective efficacy of individual oxime (HI-6) and combinations of oximes (HI-6+trimedoxime, HI-6+K203) in soman-poisoned rats.
Topics: Animals; Behavior, Animal; Drug Therapy, Combination; Male; Molecular Structure; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Trimedoxime | 2011 |
Biochemical insight into soman intoxication and treatment with atropine, HI-6, trimedoxime, and K203 in a rat model.
Topics: Animals; Antidotes; Atropine; Biomarkers; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Trimedoxime | 2011 |
A comparison of the reactivating and therapeutic efficacy of chosen combinations of oximes with individual oximes against VX in rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Lethal Dose 50; Male; Mice; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2011 |
The benefit of combination of oximes for the neuroprotective efficacy of antidotal treatment of sarin-poisoned rats.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Molecular Structure; Neuroprotective Agents; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Trimedoxime | 2012 |
The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice.
Topics: Animals; Antidotes; Cholinesterase Reactivators; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2012 |
Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain.
Topics: Animals; Aryldialkylphosphatase; Biomarkers; Brain; Cholinesterase Inhibitors; Dichlorvos; Male; Malondialdehyde; Obidoxime Chloride; Organophosphate Poisoning; Oxidative Stress; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Superoxide Dismutase; Trimedoxime | 2018 |