asoxime chloride has been researched along with hlo 7 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (62.50) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boulet, CA; Clement, JG; Hansen, AS | 1 |
| Kleine, A; Szinicz, L; Worek, F | 1 |
| Eyer, P; Klimmek, R; Spöhrer, U; Thiermann, H | 1 |
| Kirchner, T; Szinicz, L; Worek, F | 3 |
| Melchers, BP; Philippens, IH; Wolthuis, OL | 1 |
| Busker, RW; Melchers, BP; van der Wiel, HJ; van Helden, HP; Zijlstra, JJ | 1 |
| Szinicz, L; Worek, F | 2 |
| Aas, P | 1 |
| Bäcker, M; Kirchner, T; Szinicz, L; Worek, F | 1 |
| Eyer, P; Klimmek, R; Radtke, M; Spöhrer, U; Thiermann, H | 1 |
| Knopff, O; Szinicz, L; Widmann, R; Worek, F | 1 |
| Diepold, C; Eyer, P; Worek, F | 1 |
| Eyer, P; Kiderlen, D; Szinicz, L; Thiermann, H; Worek, F | 1 |
| Eyer, P; Reiter, G; Szinicz, L; Worek, F | 1 |
| Szinicz, L; Thiermann, H; Worek, F | 1 |
| Aas, P; Tansø, R; Øydvin, OK | 1 |
| Cabal, J; Hrabinova, M; Jun, D; Kassa, J; Kuca, K | 1 |
| Akfur, C; Artursson, E; Ekström, F; Hörnberg, A; Worek, F | 1 |
| Eyer, P; Thiermann, H; Worek, F | 1 |
| Baati, R; Gillon, E; Jean, L; Mercey, G; Nachon, F; Renard, PY; Saint-André, G; Verdelet, T; Wagner, A | 1 |
| Chambers, C; Luo, C; Saxena, A; Tong, M; Yang, Y | 1 |
24 other study(ies) available for asoxime chloride and hlo 7
| Article | Year |
|---|---|
Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice.
Topics: Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Imidazoles; Lethal Dose 50; Male; Mice; Neuromuscular Blocking Agents; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Sarin; Soman | 1992 |
Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning.
Topics: Animals; Atropine; Blood Pressure; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Heart Rate; Hemodynamics; Injections, Intravenous; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Pyridostigmine Bromide; Respiration | 1995 |
Pharmacokinetics of the oximes HI 6 and HLö 7 in dogs after i.m. injection with newly developed dry/wet autoinjectors.
Topics: Animals; Antidotes; Atropine; Biological Availability; Cholinesterase Reactivators; Dogs; Hematocrit; Injections, Intramuscular; Male; Oximes; Pyridines; Pyridinium Compounds; Software | 1994 |
Effect of atropine and bispyridinium oximes on respiratory and circulatory function in guinea-pigs poisoned by sarin.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Blood Pressure; Cholinesterase Reactivators; Drug Therapy, Combination; Female; Guinea Pigs; Heart Rate; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Respiration; Sarin | 1995 |
Effect of atropine, HLö 7 and HI 6 on respiratory and circulatory function in guinea-pigs poisoned by O-ethyl S-[2-(diisopropylamino) ethyl] methylphosponothioate (VX).
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Erythrocytes; Female; Guinea Pigs; Hemodynamics; Organothiophosphorus Compounds; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Respiration | 1994 |
Efficacy of HI-6 and HLö-7 in preventing incapacitation following nerve agent poisoning.
Topics: Animals; Atropine; Behavior, Animal; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Conditioning, Operant; Electroencephalography; Guinea Pigs; Lethal Dose 50; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Respiratory Mechanics; Soman | 1994 |
Comparison of the therapeutic effects and pharmacokinetics of HI-6, HLö-7, HGG-12, HGG-42 and obidoxime following non-reactivatable acetylcholinesterase inhibition in rats.
Topics: Animals; Binding, Competitive; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; In Vitro Techniques; Male; Neuromuscular Junction; Obidoxime Chloride; Oximes; Pyridines; Pyridinium Compounds; Quinuclidinyl Benzilate; Rats; Sarin; Synaptic Transmission | 1994 |
Treatment of tabun poisoned guinea-pigs with atropine, HLö 7 or HI 6: effect on respiratory and circulatory function.
Topics: Animals; Atropine; Blood Circulation; Cholinesterase Reactivators; Female; Guinea Pigs; Lethal Dose 50; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridines; Pyridinium Compounds; Respiration | 1994 |
Investigation of acute cardiovascular and respiratory toxicity of HLö 7 dimethanesulfonate and HI 6 dichloride in anaesthetized guinea-pigs.
Topics: Acetylcholinesterase; Anesthesia; Animals; Atropine; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Cholinesterase Reactivators; Female; Guinea Pigs; Heart Rate; Oximes; Pyridines; Pyridinium Compounds; Respiration Disorders; Respiratory System | 1993 |
Atropine and oxime treatment in lethal soman poisoning of anaesthetized guinea-pigs: HLö 7 dimethanesulfonate versus HI 6 dichloride.
Topics: Acetylcholinesterase; Anesthesia; Animals; Antidotes; Atropine; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Female; Guinea Pigs; Hemodynamics; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Respiration; Soman | 1993 |
In vitro effects of toxogonin, HI-6 and HLö-7 on the release of [3H]acetylcholine from peripheral cholinergic nerves in rat airway smooth muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchi; Butyrylcholinesterase; Calcium Channel Blockers; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Male; Muscle, Smooth; Obidoxime Chloride; Oximes; Parasympathetic Nervous System; Peripheral Nerves; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman | 1996 |
Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Oximes; Pyridines; Pyridinium Compounds | 1996 |
Pharmacokinetics of atropine in dogs after i.m. injection with newly developed dry/wet combination autoinjectors containing HI 6 or HLö 7.
Topics: Animals; Atropine; Binding, Competitive; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Dogs; Drug Combinations; Half-Life; Injections, Intramuscular; Male; Muscarinic Antagonists; Oximes; Pyridines; Pyridinium Compounds; Radioligand Assay; Rats; Rats, Sprague-Dawley | 1996 |
Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds.
Topics: Acetylcholinesterase; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Obidoxime Chloride; Organophosphates; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Soman | 1998 |
Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Humans; Insecticides; Kinetics; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Paraoxon; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Time Factors | 1999 |
Effect of human plasma on the reactivation of sarin-inhibited human erythrocyte acetylcholinesterase.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocyte Aging; Erythrocytes; Humans; In Vitro Techniques; Obidoxime Chloride; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Sarin | 2000 |
Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.
Topics: Acetylcholinesterase; Algorithms; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Erythrocyte Membrane; Guinea Pigs; Humans; Kinetics; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rabbits; Rats; Sarin; Species Specificity | 2002 |
Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocyte Membrane; Humans; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Phosphorylcholine; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Spectrophotometry; Time Factors | 2004 |
Pre-junctional effects of oximes on [3H]-acetylcholine release in rat hippocampal slices during soman intoxication.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Male; Neuromuscular Junction; Obidoxime Chloride; Oximes; Potassium; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tritium | 2005 |
In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2006 |
Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cloning, Molecular; Humans; Molecular Structure; Mutagenesis, Site-Directed; Organophosphates; Oximes; Pyridinium Compounds; Recombinant Proteins; Sequence Analysis, DNA; Templates, Genetic | 2009 |
Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro.
Topics: Acetylcholinesterase; Animals; Diaphragm; Humans; Male; Mice; Mice, Inbred Strains; Obidoxime Chloride; Oximes; Paraoxon; Physical Phenomena; Pralidoxime Compounds; Pyridinium Compounds | 2010 |
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Erythrocytes; Humans; Molecular Structure; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Oximes; Pyridines; Pyridinium Compounds; Soman | 2011 |
Probing the role of amino acids in oxime-mediated reactivation of nerve agent-inhibited human acetylcholinesterase.
Topics: Acetylcholinesterase; Amino Acids; Animals; Cattle; Chemical Warfare Agents; CHO Cells; Cholinesterase Reactivators; Cricetulus; Humans; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds | 2015 |