Page last updated: 2024-09-03

asiatic acid and fluorouracil

asiatic acid has been researched along with fluorouracil in 4 studies

Compound Research Comparison

Studies
(asiatic acid)
Trials
(asiatic acid)
Recent Studies (post-2010)
(asiatic acid)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
289323245,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomyasiatic acid (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, RZ; Li, JF; Pan, YM; Wang, HS; Xiao, JT; Yao, GY; Ye, MY1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Chaijaroonkhanarak, W; Chaisawang, P; Pannangrong, W; Sirichoat, A; Sripanidkulchai, B; Welbat, JU; Wigmore, P1
Chaisawang, P; Pannangrong, W; Welbat, JU; Wigmore, P1

Reviews

1 review(s) available for asiatic acid and fluorouracil

ArticleYear
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017

Other Studies

3 other study(ies) available for asiatic acid and fluorouracil

ArticleYear
Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Models, Molecular; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship

2014
Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Animals; Cell Count; Cell Proliferation; Cell Survival; Cognition Disorders; Dentate Gyrus; Exploratory Behavior; Fluorouracil; Hippocampus; Male; Neuroprotective Agents; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Spatial Memory; Time Factors

2017
Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model.
    Nutrients, 2018, Aug-09, Volume: 10, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Behavior, Animal; Cell Cycle Checkpoints; Disease Models, Animal; Doublecortin Protein; Fluorouracil; Hippocampus; Male; Memory; Memory Disorders; Nerve Tissue Proteins; Neurogenesis; Neuroprotective Agents; Oxidative Stress; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Signal Transduction

2018