Page last updated: 2024-09-03

asiatic acid and corosolic acid

asiatic acid has been researched along with corosolic acid in 16 studies

Compound Research Comparison

Studies
(asiatic acid)
Trials
(asiatic acid)
Recent Studies (post-2010)
(asiatic acid)
Studies
(corosolic acid)
Trials
(corosolic acid)
Recent Studies (post-2010) (corosolic acid)
28932321553105

Protein Interaction Comparison

ProteinTaxonomyasiatic acid (IC50)corosolic acid (IC50)
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)6.245
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)0.81

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Cosentino, LM; Fujioka, T; Hu, CQ; Ikeshiro, Y; Kashiwada, Y; Kitanaka, S; Kozuka, M; Lee, KH; Nagao, T; Okabe, H; Wang, HK; Yamagishi, T; Yasuda, I; Yeh, E1
Costerton, JW; DeLancey Pulcini, E; Eldridge, GR; Garo, E; Goering, MG; Hamilton, MA; James, GA1
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Acebey-Castellon, IL; Bouthagane, N; Doan Thi Mai, H; Gangloff, SC; Hung, NV; Lavaud, C; Le Magrex Debar, E; Litaudon, M; Muhammad, D; Roseau, N; Sevenet, T; Voutquenne-Nazabadioko, L1
Chen, J; Chen, L; Cheng, K; Gong, Y; Hao, J; Jiang, H; Li, H; Li, L; Liang, Z; Liu, H; Liu, J; Luo, C; Sun, H; Wen, X; Zhang, L; Zhang, P; Zhang, X; Zheng, M; Zhu, X1
Feng, Y; Mei, Z; Wang, C; Yang, G; Yang, J; Yang, X; Zhao, P; Zhou, Q1
Li, H; Tian, S; Wang, C; Wei, X; Wu, P; Xu, L; Xue, J1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Dong, YS; Sun, WL; Wen, C; Xing, Y; Xiu, ZL; Yu, XX; Zhang, BW1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Gou, W; Guo, J; Hou, W; Li, Y; Liu, Q; Ning, H; Shang, H; Sun, X; Wei, H1
Aguirre, MC; Alegría, S; Backhouse, N; Cassels, BK; Delporte, C; Erazo, S; Letelier, ME; Negrete, R; Silva, X1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1
Baba, K; Hiramatsu, R; Kataoka, T; Koeda, S; Suradej, B; Tanigaki, R; Waku, T1

Reviews

3 review(s) available for asiatic acid and corosolic acid

ArticleYear
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017
Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure-Activity Relationship Study.
    Journal of natural products, 2022, 05-27, Volume: 85, Issue:5

    Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cisplatin; Cysteine Endopeptidases; Drug Resistance, Neoplasm; Female; Humans; Molecular Docking Simulation; Ovarian Neoplasms; Structure-Activity Relationship; Triterpenes

2022
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018

Other Studies

13 other study(ies) available for asiatic acid and corosolic acid

ArticleYear
Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.
    Journal of natural products, 1998, Volume: 61, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Humans; Oleanolic Acid; Plants, Medicinal; Triterpenes; Viral Plaque Assay

1998
Asiatic acid and corosolic acid enhance the susceptibility of Pseudomonas aeruginosa biofilms to tobramycin.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Ciprofloxacin; Drug Synergism; Microbial Sensitivity Tests; Pentacyclic Triterpenes; Pseudomonas aeruginosa; Tobramycin; Triterpenes

2007
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
Triterpenoid saponins from Symplocos lancifolia.
    Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Magnoliopsida; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Pseudomonas aeruginosa; Saponins; Staphylococcus aureus; Triterpenes; Vietnam

2011
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Enzyme Inhibitors; Glycogen Phosphorylase, Muscle Form; Models, Molecular; Molecular Conformation; Muscle, Skeletal; Pentacyclic Triterpenes; Quantitative Structure-Activity Relationship; Rabbits; Stereoisomerism

2011
Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Animals; Cell Line; Chalcones; Crystallography, X-Ray; Eucalyptus; Glucose Transporter Type 4; Models, Molecular; Molecular Structure; Plant Leaves; Rats; Xanthenes

2014
Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Animals; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Interleukin-6; Macrophages; MCF-7 Cells; Mice; Molecular Structure; Myrtaceae; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Triterpenes; Tumor Necrosis Factor-alpha

2016
Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose.
    Bioorganic & medicinal chemistry letters, 2017, 11-15, Volume: 27, Issue:22

    Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Drug Synergism; Inhibitory Concentration 50; Kinetics; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes

2017
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
Topical anti-inflammatory activity of 2alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.
    Bioorganic & medicinal chemistry, 2006, Aug-15, Volume: 14, Issue:16

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Betulinic Acid; Dose-Response Relationship, Drug; Indomethacin; Male; Mice; Myrtaceae; Otitis Externa; Pentacyclic Triterpenes; Plant Leaves; Polycyclic Compounds; Sulfonamides; Tetradecanoylphorbol Acetate; Triterpenes

2006
Asiatic Acid, Corosolic Acid, and Maslinic Acid Interfere with Intracellular Trafficking and N-Linked Glycosylation of Intercellular Adhesion Molecule-1.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:12

    Topics: A549 Cells; Cytokines; Endoplasmic Reticulum; Glycosylation; Golgi Apparatus; Humans; Intercellular Adhesion Molecule-1; Microscopy, Confocal; Pentacyclic Triterpenes; Polysaccharides; Protein Transport; Triterpenes

2018