asenapine has been researched along with hp 873 in 14 studies
| Studies (asenapine) | Trials (asenapine) | Recent Studies (post-2010) (asenapine) | Studies (hp 873) | Trials (hp 873) | Recent Studies (post-2010) (hp 873) |
|---|---|---|---|---|---|
| 265 | 50 | 209 | 117 | 17 | 68 |
| Protein | Taxonomy | asenapine (IC50) | hp 873 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.009 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.11 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.009 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0004 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.009 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.11 | |
| D | Mus musculus (house mouse) | 0.75 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.21 | |
| 5-hydroxytryptamine receptor 2A | Bos taurus (cattle) | 0.009 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.064 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (92.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Richelson, E | 1 |
| Roman, MW | 1 |
| Howland, RH | 1 |
| Citrome, L | 1 |
| Grant, JS; Keltner, NL; Moore, RL | 1 |
| Stahl, SM; Tarazi, FI | 1 |
| Correll, CU; De Hert, M; Detraux, J; Sweers, K; van Winkel, R; Yu, W | 1 |
| Bobo, WV | 1 |
| Barr, AM; Boyda, HN; Hawkes, E; Honer, WG; Jin, CH; Pang, CC; Procyshyn, RM; Wong, D | 1 |
| Amrutheshwar, R; Dkhar, SA; George, M; Kattimani, S; Rajkumar, RP | 1 |
| Morrissette, DA; Stahl, SM | 1 |
| Mandrioli, R; Mercolini, L; Protti, M | 1 |
| Klein-Schwartz, W; Stassinos, G | 1 |
| Danek, PJ; Daniel, WA; Wójcikowski, J | 1 |
8 review(s) available for asenapine and hp 873
| Article | Year |
|---|---|
New antipsychotic drugs: how do their receptor-binding profiles compare?
Topics: Antipsychotic Agents; Brain; Clozapine; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Receptors, Neurotransmitter | 2010 |
Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles | 2011 |
Iloperidone, asenapine and lurasidone: a primer on their current status.
Topics: Adult; Animals; Antipsychotic Agents; Bipolar Disorder; Dibenzocycloheptenes; Drug Approval; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles; United States; United States Food and Drug Administration | 2012 |
Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.
Topics: Antipsychotic Agents; Bipolar Disorder; Blood Glucose; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lipid Metabolism; Lurasidone Hydrochloride; Paliperidone Palmitate; Piperidines; Pyrimidines; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Weight Gain | 2012 |
Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adults.
Topics: Antipsychotic Agents; Dibenzocycloheptenes; Drug Approval; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles | 2013 |
Newer antipsychotics and upcoming molecules for schizophrenia.
Topics: Antipsychotic Agents; Dibenzocycloheptenes; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperazines; Piperidines; Schizophrenia; Thiazoles | 2013 |
Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Clozapine; Dibenzocycloheptenes; Drug Therapy, Combination; Heterocyclic Compounds, 4 or More Rings; Humans; Impulsive Behavior; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Thiazoles; Violence | 2014 |
Novel Atypical Antipsychotics: Metabolism and Therapeutic Drug Monitoring (TDM).
Topics: Animals; Antipsychotic Agents; Dibenzocycloheptenes; Drug Approval; Drug Design; Drug Monitoring; Heterocyclic Compounds, 4 or More Rings; Humans; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; United States; United States Food and Drug Administration | 2015 |
6 other study(ies) available for asenapine and hp 873
| Article | Year |
|---|---|
Atypical antipsychotics: the two new arrivals.
Topics: Antipsychotic Agents; Bipolar Disorder; Dibenzocycloheptenes; Drug Approval; Heterocyclic Compounds, 4 or More Rings; Humans; Isoxazoles; Piperidines; Safety; Schizophrenia; Treatment Outcome; United States; United States Food and Drug Administration | 2011 |
Update on newer antipsychotic drugs.
Topics: Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Child; Clinical Trials as Topic; Dibenzocycloheptenes; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Male; Piperidines; Pregnancy; Schizophrenia; Thiazoles; Treatment Outcome | 2011 |
Biological perspectives: update on newer antipsychotic drugs: are they evidence based?
Topics: Antipsychotic Agents; Cyclooxygenase 2 Inhibitors; Dibenzocycloheptenes; Evidence-Based Medicine; Heterocyclic Compounds, 4 or More Rings; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Isoindoles; Isoxazoles; Lactones; Lurasidone Hydrochloride; Piperidines; Psychotic Disorders; Pyridines; Serotonin Receptor Agonists; Sulfones; Thiazoles | 2011 |
Metabolic side-effects of the novel second-generation antipsychotic drugs asenapine and iloperidone: a comparison with olanzapine.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Dibenzocycloheptenes; Fasting; Female; Glucose Clamp Technique; Glucose Tolerance Test; Heterocyclic Compounds, 4 or More Rings; Hyperinsulinism; Insulin Resistance; Isoxazoles; Metabolism; Olanzapine; Piperidines; Rats; Rats, Sprague-Dawley | 2013 |
Asenapine, iloperidone and lurasidone exposures in young children reported to U.S. poison centers.
Topics: Antipsychotic Agents; Child, Preschool; Dibenzocycloheptenes; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Infant; Isoxazoles; Lurasidone Hydrochloride; Male; Piperidines; Poison Control Centers; Retrospective Studies; United States | 2018 |
Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy.
Topics: Antipsychotic Agents; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dibenzocycloheptenes; Drug Interactions; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoxazoles; L-Lactate Dehydrogenase; Lurasidone Hydrochloride; Piperidines; RNA, Messenger | 2020 |