asenapine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 4 studies
| Studies (asenapine) | Trials (asenapine) | Recent Studies (post-2010) (asenapine) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 265 | 50 | 209 | 3,530 | 7 | 389 |
| Protein | Taxonomy | asenapine (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| De Boer, T; De Vos, CJ; Tonnaer, JA; Van Delft, AM | 1 |
| Henry, B; Moran-Gates, T; Shahid, M; Tarazi, FI; Wong, EH | 1 |
| Blier, P; El Mansari, M; Ghanbari, R; Shahid, M | 1 |
4 other study(ies) available for asenapine and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Neurochemical studies with the potential antipsychotic compound trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Benzazepines; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dibenzoxepins; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Membranes; Mianserin; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Yohimbine | 1990 |
Asenapine induces differential regional effects on serotonin receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Brain; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin | 2010 |
Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Amphetamines; Animals; Apomorphine; Brain; Clonidine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists | 2009 |