ascorbic-acid has been researched along with pheophorbide-a* in 1 studies
1 other study(ies) available for ascorbic-acid and pheophorbide-a
| Article | Year |
|---|---|
Preventive effects of L-ascorbic acid and calcium pantothenate against photosensitive actions induced by pheophorbide alpha and hematoporphyrin.
The preventive effects of L-ascorbic acid (V.C) and pantothenic acid (PaA) against photosensitized hemolysis in the presence of pheophorbide a or hematoporphyrin were investigated in vitro. The development of hematoporphyrin-induced photosensitivity and the preventive effects of V.C and PaA were also investigated in male mice. V.C and PaA exerted preventive effects against photosensitized hemolysis in the presence of pheophorbide a or hematoporphyrin. In such cases, V.C and PaA had not only an additive effect but also a synergistic one. The time required for the photosensitized acute shock-like death (i.e., survival time), was significantly extended by simultaneous administration of V.C and PaA. This supports the findings of in vitro experiments. Topics: Animals; Ascorbic Acid; Chlorophyll; Drug Synergism; Hematoporphyrins; Hemolysis; Light; Male; Mice; Pantothenic Acid; Photosensitivity Disorders; Rats | 1981 |