ascorbic-acid and methyl-oleate

ascorbic-acid has been researched along with methyl-oleate* in 2 studies

Other Studies

2 other study(ies) available for ascorbic-acid and methyl-oleate

Article	Year
Inhibition of the bacterial mutagenicity of N-methyl-N'-nitro-N-nitrosoguanidine by ascorbic acid and ascorbyl palmitate. Mutation research, 1994, Volume: 321, Issue:1-2 The mechanism of antimutagenic activity of ascorbic acid (AA) and its derivatives was studied using the Salmonella typhimurium TA100 bacterial test system. All substances studied inhibited N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutagenesis. Ascorbyl palmitate (AP) markedly decreased the numbers of his+ revertants, behaving as a membrane-active antimutagen. A comparative study of the antioxidative activity of the investigated substances in the methyl oleate (MO) system has demonstrated that AA and its derivatives have pro-oxidant properties within the limits of the concentrations studied. The results obtained do not agree with the common view of the mode of action of these antimutagens, including both inhibition of free radical processes and MNNG reductive inactivation. Topics: Antimutagenic Agents; Antioxidants; Ascorbic Acid; Biotransformation; Dose-Response Relationship, Drug; Free Radicals; Membrane Lipids; Methylnitronitrosoguanidine; Mutagenicity Tests; Oleic Acids; Oxidants; Oxidation-Reduction; Salmonella typhimurium; Suppression, Genetic	1994
A comparison of the rates of ozonation of biological antioxidants and oleate and linoleate esters. Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2 The rates of reaction with ozone of some biological antioxidants and simple polyunsaturated fatty acids (PUFA) have been measured in water or in aqueous micellar solutions. At pH 7.0 the rate constants are ca. 10(6) M-1 sec-1 for urate, alpha-tocopherol, and PUFA, and 6 X 10(7) M-1 sec-1 for ascorbate. When ozone-containing air is breathed, ascorbate in the lung may undergo direct ozonation. However, alpha-tocopherol is probably spared direct reaction with ozone because it doesn't effectively compete with PUFA in pulmonary membranes; rather, tocopherol is used to scavenge radicals produced from the ozone-PUFA reaction. Topics: Antioxidants; Ascorbic Acid; Chemical Phenomena; Chemistry; Fatty Acids, Unsaturated; Linoleic Acid; Linoleic Acids; Oleic Acid; Oleic Acids; Ozone; Uric Acid; Vitamin E	1985

Article

Year

Inhibition of the bacterial mutagenicity of N-methyl-N'-nitro-N-nitrosoguanidine by ascorbic acid and ascorbyl palmitate.

Mutation research, 1994, Volume: 321, Issue:1-2

The mechanism of antimutagenic activity of ascorbic acid (AA) and its derivatives was studied using the Salmonella typhimurium TA100 bacterial test system. All substances studied inhibited N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutagenesis. Ascorbyl palmitate (AP) markedly decreased the numbers of his+ revertants, behaving as a membrane-active antimutagen. A comparative study of the antioxidative activity of the investigated substances in the methyl oleate (MO) system has demonstrated that AA and its derivatives have pro-oxidant properties within the limits of the concentrations studied. The results obtained do not agree with the common view of the mode of action of these antimutagens, including both inhibition of free radical processes and MNNG reductive inactivation.

Topics: Antimutagenic Agents; Antioxidants; Ascorbic Acid; Biotransformation; Dose-Response Relationship, Drug; Free Radicals; Membrane Lipids; Methylnitronitrosoguanidine; Mutagenicity Tests; Oleic Acids; Oxidants; Oxidation-Reduction; Salmonella typhimurium; Suppression, Genetic

1994

A comparison of the rates of ozonation of biological antioxidants and oleate and linoleate esters.

Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2

The rates of reaction with ozone of some biological antioxidants and simple polyunsaturated fatty acids (PUFA) have been measured in water or in aqueous micellar solutions. At pH 7.0 the rate constants are ca. 10(6) M-1 sec-1 for urate, alpha-tocopherol, and PUFA, and 6 X 10(7) M-1 sec-1 for ascorbate. When ozone-containing air is breathed, ascorbate in the lung may undergo direct ozonation. However, alpha-tocopherol is probably spared direct reaction with ozone because it doesn't effectively compete with PUFA in pulmonary membranes; rather, tocopherol is used to scavenge radicals produced from the ozone-PUFA reaction.

Topics: Antioxidants; Ascorbic Acid; Chemical Phenomena; Chemistry; Fatty Acids, Unsaturated; Linoleic Acid; Linoleic Acids; Oleic Acid; Oleic Acids; Ozone; Uric Acid; Vitamin E

1985